The Pharmanex Story

The vision of Pharmanex was conceived in 1994 by a leading pharmaceutical scientist, Dr.
Michael Chang and a successful entrepreneur, Bill McGlashan, Jr. Their vision was to create
beneficial products, which applied the methodologies and disciplines of western
pharmaceutical science to natural products, producing dietary supplements of proven safety
and efficacy. The company they formed has literally set a new industry standard for quality
and scientific integrity.

During his 15 years in the pharmaceutical industry, Dr. Michael Chang

searched for ways to protect, preserve, and improve people's health. As
Deputy Director of Medicinal Chemistry at Merck, Sharp and Dohme he
managed screening activities, which involved traveling around the world
looking for "Magic Bullets," those single chemicals that could be taken
from a natural source and turned into a drug. In that process, Michael
examined 50,000 different extracts searching for a single chemical that
could be patented and taken through the drug discovery process. "I knew
the ingredients existed, but the process was too complicated and
expensive," says Dr. Chang. Isolating individual molecules that could be
patented by the drug companies often resulted in less effective products with more side
effects. Dr. Chang found that natural substances frequently work together to benefit the
human body. He began to realize the tremendous potential of natural products created,
refined and substantiated through a scientific pharmaceutical approach. So, after 10 IND
(Investigational New Drug) and 3 NDA (New Drug Approval) filings, Michael left his position
as Director of Medicinal Chemistry at Rhone-Poulenc Rorer to pursue his vision.

His extensive experience in starting and building companies prepared Bill McGlashan, Jr. to
create and drive the vision that he and Dr. Chang defined in 1994. Mr. McGlashan invested
millions of dollars of capital with Bain Capital & Information Partners; he co-founded and
managed TRADE, Inc. and Generation Ventures. He realized that to establish the leading
nutritional health- care company he would need to involve top scientific and business
leaders. He began a search for leaders that shared their vision and determination.

The world-renowned scientist Dr. Carl Djerassi of Stanford University, a winner of both the
National Medal of Science Award and the National Medal of Technology Award, the principal
inventor of the oral contraceptive, and a founder of Syntex Corporation shared the
Pharmanex vision. He became the first investor in the new company as well as the chairman
of the distinguished Pharmanex Scientific Advisory Board.

The Pharmanex Scientific Advisory Board, along with the Medical Advisory Board chaired by
Dr. David Heber, M.D., Ph.D., Director of the Center for Human Nutrition at UCLA, include
leading scientists from around the world. These scientists are from major institutions
including: Columbia University, Kansas University, The Scripps Research Institute, Tufts
University, UC Davis, and UC Berkley. The Pharmanex Scientific Advisory Board includes
scientists from Japan, Hong Kong, Taiwan and Korea. Board members are actively involved
in clinical research and product development.

In addition, Pharmanex has more than 60 scientists on staff and more than 150
collaborating scientists at leading academic centers around the world:
 • UCLA
• UCSF
• Harvard
• Cornell
• Columbia
• Stanford
• Tufts
• Kansas University
• Shanghai Medical University
• Peking University
• Beijing Medical University
• Institute of Materia Medica

This network of scientists constitutes a product development engine unparalleled in the

marketplace. The efforts of this incredible array of scientific talent are directed by Dr.
Joseph Chang, President of Pharmanex with twenty years of experience in biotechnology
and the pharmaceutical industry, and Dr. Ray Cooper, Executive Director of Research and
Scientific Affairs with over 15 years of experience in pharmaceutical development.

Leading investment companies with major stakes in bio-technical companies also shared the
vision. Initial investors included:

• Fidelity Investments, America's largest privately held investment manager with $1

trillion in customer assets
• Chase Capital, a global private equity organization with $7 billion under
management, investing in numerous leading healthcare companies
• The Pritzker Organization, founders of Hyatt Hotels and owners of the Marman Group
• J.H. Whitney, one of the first private equity firms in the world founded in 1946

In 1998, Pharmanex joined with a major, global marketing company to help spread our
product and business benefits to millions of deserving people throughout the world.

Because of the vision of individual scientists, business leaders, investors, and individuals like
you, Pharmanex is now realizing the vision conceived in 1994 with superior products
"Provided by Nature-Proven by Science."