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MICR

BURKHOLDERIA CEPACIA
O

BACTERIA SOURCES CLINICAL FEATURES WORKUP NOSOCOMIAL INFECTIONS TREATMENT PREVENTION

...A painless lesson is one without any meaning. ^_^ shar ^_^ 1
MICR
BURKHOLDERIA CEPACIA
O

Burkholderia cepacia Source Vehicle • History Laboratory Studies Infection Predisposing • Because B. • Minimize
• Original name: Personnel Hands, o A history of the use of • Culture B. Factors cepacia is almost and
Pseudomonas antiseptic irrigant solutions that cepacia from Catheter- In-dwelling always a prevent Px
cepacia soaps, potentially may body fluids: associated urinary colonizer, to Px
• Other names: and hand contain B. cepacia is o Although B. bactereuria catheters antimicrobial is spread of B.
o P. multivorans lotions epidemiologically cepacia (+) IV line Central IV often unnecessary cepacia by
o P. kingii Respirato Respirator important cultures infections catheters and may be effective
• Original ry y tubing, from non harmful infection
classification: equipme condensa • Physical sterile sites • Resistance to control
o Pseudomonas nt and/or te o PE is referable to the (respiratory Urosepsis UT major antibiotics measures
(genus) fluids Ultrasonic organ system involved secretions, instrumentat expected esp.
nebulizer urine in the ion • Patterns of handwashin
• 2 important
Inhalation • Features from superficial setting of Primary Areterial resistance differs g
organisms form the
medicatio to deep- seated infections Foley bacteremia monitoring from P. • Use of
genus Burkholderia
ns and disseminated catheters) devices aeruginosa Foley
o B. cepacia
IV Lines IV infection are seen nearly Pseudobactere Contaminati • B. cepacia is often catheters
o B. pseudomallei
and/or solutions o Pneumonia always mia on of blood susceptible to as long as
meliodiosis represent
fluids Central  rare pulmonary during TMP-SMZ, necessary
• Transmission: venous colonization
pathogen except collection ceftazidime, • Avoid their
o Inhalation catheters , presence
in patients with and/or cefepime, use in
o Contact of cut or Pressure Pressure in sterile compromis
CF and CGD processing meropenem, or
abraided skin monitorin transduce body fluids ed hosts
 respiratory of blood imipenem, and
with g devices r fluids such as predispose
system most cultures has varying
contaminated Urine In- blood d to UTI
common site of susceptibility to
soil or water and/or dwelling mandates
isolation; majority fluoroquinolones • Preventing
 Produce abcesses fluids foley consultation
are colonizers • Drugs colonization
 Chronic infection: catheters with an of
 in the US: 6%- 7% o TMP-SMZ
mimics TB Urometer infectious respiratory
of adults CF Px o Chloramphenic
s disease secretions
are infected and ol
History Irrigation specialist to in
20% - 30% o 3rd gen.
• 1949: Walter solutions help intubated
develop cepacia differentiate cephalosporins
Burkholder of Cornell patients
syndrome colonization , esp.
Univ.- first described who are in
o Bacteremia from ciftazidime
P. cepacia (known as ICUs and on
 Portals of entry: infection. o Ureidopenicillin
B. cepacia) broad-
respiratory tract o PCR – with o Quinolones
• A phytopathogen spectrum
(most common), genotyping o Meropenem
responsible for the antibiotics
central venous o 7 • Use of
bacterial rot of is difficult
catheter genomovars combination
onions (cepa=onion) • Effective
 Asymptomatic to therapy to
fulminant septic infection
Characteristics achieve a clinical
shock (DIC) control
• Aerobic gram (-) response
o SSTI measure or
bacillus found • Combination of B
...A painless lessoninissoil,
one without any meaning. ^_^ shar ^_^ 2
MICR
BURKHOLDERIA CEPACIA
O

...A painless lesson is one without any meaning. ^_^ shar ^_^ 3

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