THE REAL ACTION

Calcicare Syrup is the only that contains the RDA of Vitamin D3.
Calcicare Syrup is the best option for strong bones & teeth.
Calcicare Syrup is essential to prevent the risk of RICKETS.
Calcicare Syrup is highly accepted due to its strawberry flavor.

Dosage:
2.5-5 ml once daily (meeting the real need for Vit. D3)

Each 5 ml contains:
Vitamin D3 (Cholecalciferol) 400 I.U. (10 µg)

Calcium Glubionate 760 mg (equiv. to 50 mg elemental calcium)

References: 1. A Dawodu, C L Wagner. Mother-child Vitamin D Deficiency: An International Perspective. Arch Dis Child 2007 92: 737-740. 2. Holick MF. Sunlight
and Vitamin D for Bone Health and Prevention of Autoimmune Diseases, Cancers and Cardiovascular Disease [Review]. Am J Clin Nutr 2004;80(6 Suppl):1678S–-
1688S. 3. S. Bowden, R. Robinson, et al. Prevalence of Vitamin D Deficiency and Insufficiency in Children With Osteopenia or Osteoporosis Referred to a Pediatric
Metabolic Bone Clinic. Pediatrics 2008;121;e1585-e1590. 4. A. Dawodu. Vitamin D status of Arab Mothers and Infants. J Arab Neonatol Forum 2004; 1:15-22. 5. C.
Wagner, F. Greer. Prevention of Rickets and Vitamin D Deficiency in Infants, Children, and Adolescents. Pediatrics 2008;122;1142-1152. 6. Canadian Paediatric
Society, Vitamin D supplementation: Recommendations for Canadian Mothers and Infants. Paediatric Child Health 2007;12(7):583-9.

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SERIOUS PROBLEMS NEED... ...SERIOUS ACTIONS
Vitamin D3 deficiency RICKETS still exists as a public health Health measures to improve the Vitamin D3 status of infants
problem with significant morbidity in the Middle East.1
should include:4 OH

Current life style severely limits skin exposure to sunlight H 3C

CH3
H
CH3

so increasing the risk of Vitamin D3 deficiency.1 CH3

It is now strongly believed that Vitamin D3 deficiency is Wide spread of Vitamin D3 supplementation. H

the main cause of Rickets & delayed dentition among CH2

children not low serum Calcium concentrations. 2 HO OH

Modest skin sunshine exposure.

90

80
Diminished Vitamin D3 supply leads to decreased 70
Increase of food fortified with Vitamin D3.
intestinal absorption of calcium, which 60
subsequently results in increased PTH secretion

PTH,pg/mL
50

and so increased bone turnover.3 40 It is now recommended that all infants and children have a minimum daily intake
30
of 400 I.U. of Vitamin D3 beginning soon after birth.5,6
20
Calcicare Syrup composed of a balanced formula of Calcium & Vit. D3
10
(active form of Vitamin D) that is important for calcium homeostasis
0
0 20 40 60 80 100 & bone mineralization during growth time.
Serum 25-OHD, ng/mL
Inverse relationship between serum 25-OHD and intact PTH levels (p<.01).