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in its usual concentration. Now the flow property of X comes in the range of 5-15. The excepient Y is& .
A) A lubricant
B) A glidant
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C) A Binder
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D) both a and b
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Correct Answer is B
EXP : Explanation: Glidant is used to enhance flow property. The percentage compressibility in 5-15 is
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excellent. (Table 8.4 Lachman). Glidants are talc-5%,corn starch 5-10 %, colloidal silica such as
Cab-o-Sil or aerosol 0.25-3 5 concentration. This part is important and to be studied with proper
attention.
Correct Answer is A
3) A weakly acidic drug A with acid dissociation constant (pKa) 1.2 was administered orally. Calculate
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A) 1%
B) 0%
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D) 1.00%
Correct Answer is B
constant, the percentage ionized fraction is equal to unionized means both are equal i.e. 50%.
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4) In disperse systems flocculation occurs when Zeta potential:
A) Increases
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B) Decreases
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C) Remains as such
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Correct Answer is B
EXP : When Zeta potential decreases flocculation occurs because of cohelesence of the particles due to
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reduced free energy.
5) Suspending agents commonly used in suspensions act through following most appropriate
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mechanism:
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C) Increases viscosity
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D) Decrease viscosity
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Correct Answer is C
EXP : Thickning agets are used as suspending agents to make particles suspended in the continuous
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phase.
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A) W/O emulsion
B) Microemulsion
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C) O/W emulsion
Correct Answer is B
EXP : in microemulsion the globule size is in microrange that is not visible with naked eyes hence looks
transparent.
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7) An o/w emulsion is stabilized with sodium stearate; upon addition of calcium chloride lead to
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formation of w/o emulsion; the phenomenon is known as
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A) Breaking of emulsion
B) Creaming of emulsion
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C) Phase inversion
D) Coalescence
Correct Answer is C
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8) Which of the following type of surfactant category is commonly used to produce stable emulsions:
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A) Anionic surfactant
B) Cationic surfactant
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C) Nonionic surfactant
Correct Answer is C
A) Surfactants
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B) Preservatives
C) Antioxidants
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Correct Answer is A
B) pH scale-Sorenson
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C) HLB scale-Fick s Theory
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Correct Answer is C
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EXP : HLB scale is concerned with Griffin
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A) Salmonella typhi
B) S. aureus m
C) Helicobector pylori
D) All of these
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Correct Answer is C
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12) A patient suffering from glaucoma. He has to travel by ship in the sea. Which of the following
should be avoided:
A) Cyclizine
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B) Diphenhydramine
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C) Promethazine
D) Scopolamine
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Correct Answer is D
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EXP : All the drugs in this category are antiemetics and used in motion sickness. Scopolamine acts by
its anticholinergic action hence is contraindicated in glaucoma. Cyclizine, buclizine are antihistaminics
and are effective in motion sickness. Promethazine is the exception from Phenothiazine categorythat is
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having activity in motion sickness by virtue of probable antihistaminic activity. Other phenothiazine
derivatives like chlorpromazine, triflupromazine are ineffective in motion sickness that occurs during
A) Sedates CTZ
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B) Accelerates gastic emptying
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C) Both a and b
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D) Act on heart to reduce anxiety
Correct Answer is C
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EXP : Metoclopromide is acts by dual mechanism; sedates Chemoreceptor trigger Zone (CTZ) and
increase contractility of smooth muscles of upper GIT hence casuse antiemetic action
A) Cimetidine
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B) Ranitidine
C) Cetrizine
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Correct Answer is C
.b
EXP : Omeprazole, lansoprazole, pantoprazole acts on (inhibit) H+ Potassium ATPase pump (proton
pump) system of the gastic parietal cells. It is ultimate step in gastic acid production.
16) Triple therapy regimen for eradication of Helicobactor pylori includes following therapy for seven
days
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A) A proton pump inhibitor, A macrolide and amoxicillin or metronidazole
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C) A PG1 blocker, amoxicillin, metronidazole
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D) Sucralfate, amoxicillin and metronidazole
Correct Answer is A
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EXP : Triple therapy regimen includes A proton pump inhibitor like omeprazole, A macrolide like
clarithromycin and amoxicillin or metronidazole for eradication of H.pylori (FSK BARAR p.538)
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17) An ideal bronchodialator would act via
Correct Answer is A
.b
18) Salbutamol is
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D) An antiallergic
Correct Answer is B
19) Zafrileukast is an
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A) Beta 2 agonist
D) H1 receptor antagonist
Correct Answer is C
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EXP : Zafrileukast is an Cystenyl-leukotriene receptor antagonist. Other drug from this category is
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monteleukast.
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20) Usually in acute asthamatic attack the following is given along with a bronchodialator:
A) Aspirin
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B) Cetrizine
C) Adrenaline
D) Beclomethasone
Correct Answer is D
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EXP : Beclomethasone is usually given with bronchodialator like salbutamol/salmeterol. This acts as
non specific anti-inflammatory agent too provide relief from congestion and exudation.
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Correct Answer is D
B) Oleo-resin
C) Balsam
D) Gum-resin
Correct Answer is A
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23) Clove contains volatile oil& .
A) Eugenol, a phenol
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B) Pinene, a sesquiterpene
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C) Eugenol, an aldehyde
D) Cineole, a ketone
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Correct Answer is C
B) Limonene (30%)
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C) Carvone (60%)
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D) Eugenol (40%)
Correct Answer is C
Correct Answer is C
Correct Answer is A
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A) Condensed tannins
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B) Condensed & hydrolysable tannins
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C) Hydrolysable tannins
D) Complex tannins
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Correct Answer is A
Correct Answer is B
A) Citral
B) Limonene
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C) Both a & b
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D) Citronellal
Correct Answer is B
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D) A Volatile oil, Anti-inflammatory & Antioxidant properties & derived from phenylalanine
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Correct Answer is A
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A) Eugenol, a sesquiterpenoidal volalile oil
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B) Eugenol, a diterpenoidal volalile oil
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D) Eugenol, a polyterpenoidal volalile oil
Correct Answer is A m
32) The chemical nature of Eugenol is& .
A) Ester
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B) Ketone
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C) Aldehyde
D) Ether
Correct Answer is B
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A) Alpha rays
B) Beta rays
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C) Gama Rays
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D) X-Rays
Correct Answer is C
A) Noradrenaline
B) Ephedrine
C) Acetylcholine
D) Adrenaline
Correct Answer is A
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35) O-Hydroxyl benzaldehyde in the presence of alkaline hydrogen peroxide gives Catechol, the
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reaction is known as....
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A) Diazen condensation
B) Dakin reaction
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C) Diels-Alder reaction
D) Dieckmann condensation
Correct Answer is A
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36) In Meerween-Ponndorf- Verly reduction reaction....
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A) Carbonyl compounds reduced to respective acid
Correct Answer is B
Correct Answer is B
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C) non-heredity disease
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Correct Answer is A
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39) Select the irrational evaluation parameters for volatile oils, specified in BP&
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B) Foreign ester content based on residue after evaporation
Correct Answer is B
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40) Fabry s Disease is& ..
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Correct Answer is A
A) Reverse of glycolysis
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D) All of these
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Correct Answer is D
B)
C) Both a & b
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D) none of the above
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Correct Answer is
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43) Select the false statement for volatile oils& .
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B) These are evaluated for their optical roatation, refractive index & Relative density units:Isoprenoid
units
Correct Answer is D
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44) Select a glycogen storage disease of type II disease
A) Phenylketourea
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B) Anderson s disease
C) Krabbe s disease
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D) All of these
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Correct Answer is B
A) Gaucher's disease
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B) Anderson s disease
D) Gluconeogenesis
Correct Answer is A
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B) Known Wild type gene sequence
C) Uracil deglycosidase
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D) All of these
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Correct Answer is A
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A) cleave within or at short specific distances from recognition site
A) RY13:Strain
B) Order of identification
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C) Restriction
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Correct Answer is A
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49) Select the RNA genetic codon for amino acid, leucine& ..
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A) UUA
B) UUC
C) CUG
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D) All of these
Correct Answer is D
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C) UAG,UGA & UGG
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D) UAG & UGG
f.c
Correct Answer is A
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