Biennial Report 2003-05

The Organization The Organization The Organization The Organization The Organization
Indian Institute of Chemical Technology (IICT),

Hyderabad, a national Laboratory and a constituent
of Council of Scientific & Industrial Research (CSIR), is
a premiere R&D Institute in India. Established in
1944,the Institute has made significant contributions
in the field of Chemical Sciences & Technology. Major
areas of research are: Agrochemicals, Drugs &
Pharmaceuticals, Organic Intermediates, Lipid Science
and Technology, Organic Coatings & Polymers,
Catalysis, Coal, Chemical Engineering and Design &
Engineering , Chemical Biology and Chemical
Informatics
The Vision The Vision The Vision The Vision The Vision
To Become an innovative global R&D provider in
the field of chemical technology with reference
to industrial and speciality chemicals
To Be an institution of international excellence in
basic research in organic chemistry and allied
adjacent chemical and engineering sciences.
The Mission The Mission The Mission The Mission The Mission
To Provide globally competitive environmentally
friendly technologies in agrochemicals,
drugs,organic intermediates, fine chemicals, lipid
sciences and technology, speciality polymers and
allied chemicals.
To Achieve world class expertise in frontier areas in
organic synthesis, heterogeneous and
homogeneous catalysis and chemical process design,
modelling and simulation.
To Build technical competence to offer science based
technical services world over in relevant areas of
chemical. biological and engineering sciences.
IICT endeavours to provide high quality analytical endeavours to provide high quality analytical endeavours to provide high quality analytical endeavours to provide high quality analytical endeavours to provide high quality analytical
services which foster international standard basic and services which foster international standard basic and services which foster international standard basic and services which foster international standard basic and services which foster international standard basic and
applied research outputs in chemical, biological and applied research outputs in chemical, biological and applied research outputs in chemical, biological and applied research outputs in chemical, biological and applied research outputs in chemical, biological and
engineering sciences with a high degree of satisfaction and engineering sciences with a high degree of satisfaction and engineering sciences with a high degree of satisfaction and engineering sciences with a high degree of satisfaction and engineering sciences with a high degree of satisfaction and
confidence to the customers with continual improvement. confidence to the customers with continual improvement. confidence to the customers with continual improvement. confidence to the customers with continual improvement. confidence to the customers with continual improvement.
28-01-2004 28-01-2004 28-01-2004 28-01-2004 28-01-2004
ISO 9001: 2000 Accredited Laboratories
Mass Spectrometry
X-ray Crystallography
Nuclear Magnetic Resonance
Analytical Chemistry
Scanning Electron Microscopy
Organic Coatings and Polymers
Coal/Gas Characterization
Thermal Analysis
Properties Evaluation
Paper Testing
Toxicology
Pharmacology
CONTENTS
Page No.
O |vt ........ I
O FOREWORD ........ II
O IICTS R&D APPROACH AND OUTPUTS - OVERVIEW ........
* R & D Approach ........ V
* Organi sat i on St ruct ure ........ VI
* Research and Management Councils ........ VII
* Human Resource St rengt hs ........ IX
* Appl i ed Research Out put s ........ XI
* IPR Prot ect ion ........ XII
* Publicat ions record ........ XIV
* Financial Performance ........ XV
* Performance Indicat ors per Scient ist ........ XVII
O tv = +t ott (t+ 5, 2003 5, 2003 5, 2003 5, 2003 5, 2003 o t+ 4, 2004 4, 2004 4, 2004 4, 2004 4, 2004) ........ 3
O DIAMOND JUBILEE CELEBRATIONS ........ 9
O SECTORIAL R&D PERFORMANCE ........
* CSIR Net work Proj ect s ........ 21
* Nat ural Product s ........ 30
* Drugs & Pharmaceut icals ........ 33
* Agrochemicals & Pheromone Chemicals ........ 43
* Specialit y & Fine Chemicals ........ 47
* Fl uoroorgani cs ........ 48
* Inorganic & Physical Chemist ry ........ 50
* Lipid Science & Technology ........ 55
* Organic Coat ings & Polymers ........ 60
* Coal, Gas & Energy ........ 62
* Chemical & Inst rument Analysis and NMR ........ 64
* Bi ol ogy ........ 70
* Pharmacol ogy ........ 73
* Chemical Engineering Sciences ........ 74
* Mechanical Design & Engineering ........ 81
* Comput er Cent re ........ 84
* Bi oengi neeri ng and Envi ronment Cent re ........ 86
* General Engineering Services ........ 89
* Pilot Plant (Upscaling) Facilit ies ........ 90
* Busi ness Management ........ 91
* Research Management ........ 95
* Inf ormat i on Management ........ 96
O OO OO HUMAN RESOURCE DEVELOPMENT
* Trai ni ng Programme ........ 99
* Symposi a, Semi nars, Workshop, et c. ........ 100
* Honours & Awards ........ 103
* St af f Li st ........ 105
* Di st i ngui shed Overseas Vi si t ors ........ 112
O ANNEXURES
* New Cont ract s Si gned/ Assi gnment s Undert aken ........ 115
* Technol ogi es / Processes Demonst rat ed ........ 128
* Technologies / Processes / Repor t s Released ........ 129
* Pat ent s Filed ........ 135
* Pat ent s Grant ed ........ 140
* Publ i cat i ons ........ 144
Compiled, Edit ed & Produced by : Busi ness Management Di vi si on
Indian Inst it ut e of Chemical Technology
Hyderabad - 500 007
|vt
=t+t+ tt+|-+ stt|++t -t- + |- t|++ |-t- +t |
.2003-2005) -+ s+t --~ i + 2003-2004 + -tt- -t- - --t
t+ ++t tt -t+t t s+t+t-t +t -~ t+ ++t | + +
: s+|+ + -tt, + |-t- + 2003-2004 + -tt- 10 | --+t+ +t-t
.2002-2007) + ++t +t+t-+- - =t s+t vt-+t i
|-t|-+ | + -tt- -t- - -+ |+ +t++/|-t/+t+t-t/
s|~ -t+/|==t+~ :-+t|- --t t+ ++t +v -t- - t+t|+
|++i t+ ++t -+|-+ --~ |-t- + -+ +t+ t +: i -
vt.+.t. t~- + +t++t- .11 -t,1996-30 |+-+, 2003) + --t+ +
-t- +t +t+ =t ++ +, 2003 =t-t, ++ -t-+ ~, t t |++ - t-,
--~ --t t|- -t- t s|+ -t- - --| st-+ +- +
|- -t- +t |-t |-- |-+i t s+t t +- - t -t- +tt |+t +t t + t t
i : + +t:- |++ ++ --- .62), -t|-+ --- .56), s+t|+ -t|-+ - .408) +t +t + t+ v .-.18.5
+t v) t. . t: . t. +t -+ s+t+t-tt s t - t s+t+t-tt +t - -t t v |-+ti
-t- - -+ ++ -|+t-t .2003-2005) t= +| t t. . t:. t. --+ -|+t-tt, .+)
+t+|-+ t+-t + |- |+ stt|++t +t |+t +t .) |+ -- s|+--t-+ t+-, s+ --t-
+ |- |+ s+t+t-t .-tv- -+t-t) +t =|+t |-=t t i + -+ --- t. . t:. t.
-|+t-tt +t -t |~ |-+t ++t i
+ t --~ -|+t-t t- s- +t - -t+t- + -t t-t -t stt|++t +t+-
+: +t -t--t =t+t+ tt+|-+ stt|++t -t- +t -t|-+ |+-+t +t |=+---t |=+t|+t +tt
+t -t= t+t i : -|+t-t stt|++t |=t+ .DBT) - =t t++t +t i : | + -tt- t=
+t +-+t-+ -t +t +: -+ --~ -|+t-t : s+t
-t +t +t .t-t| t+-), - + t - 134 . t +, -t-), +|-+ .- + t), vt
: .t: t t), +--- .t -t t - ), -t- =t +- +t vt+|-+ .-t t -t), + ++ -t -t
.+-)i +-- -+~ -+ +t+t -|+t-tt + |- t: t: t -t - s |-t + t+t |+- +t t
.t-t-), -+t |-+-t:- .++), v-t- .+) |+t-- .|---tv) :-+t|- +t =t t+|++ |++t i
-t- - -t t t - -+~t +t t t -+~ + t .+) +|+- -t |+- |-+~ +-: .CACT)
.) - - stt|++t +t+- +: .PBPC) +t .+) -t |+t- t --+-t||+ t s |tt +t =t -
|++t i :+ |+|++, vt-t + s~t-t +- -t -t+ -s~ t- -+ |+t+- +t -t -t+ +- |+t+- s~t-t
+t =t -t- - st-+ |++t i +tt- +: t t - -+|++, t-t t--- +++ -+- -t- + -
|v+ t+-tt- +t t - - -t:- |-+~ +t |t t-t +t- + tt-t+ t+ +t =t -t--t : i
|-+ -- , |-t|- + | + -t t- t: t: t -t +t --|+t - 10| - -+t + +t-t + -++ + t-
t-t tt +t-tt +t -t +- +t |-t t- + |- st-t|+ |++t i -+-+ =t+ + +t-
|-t- +t + t+t -- +- +t-t s+- s=t+ + s|+ +t -t- --t s+- s=t+t -+<
-t- |+t t -+ |=t+t tt |-+ ++ +t+ + --t t=t +++ ++ ++t +t: -+t i
-t+t-
t-, 2006
.vt . .o. =t)
|-- +
FOREWORD
The Biennial Report period (2003-2005) is significant for t he Indian Inst it ut e
of Chemical Technology in several ways. Th e In st i t u t e cel eb r at ed i t s Di amo n d
Jubilee during 2003-04 and in addit ion t o t he review of progress done by t he lab
from Golden Jubilee t o Diamond Jubilee period, t he report also t hrows light on t he
Inst it ut es mid per formance of t he 10t h Five-Year Plan (2002-07) during 2003-04.
The Inst i t ut e cel ebrat ed i t s Di amond Jubi l ee i n a bi g way wi t h speci al
programmes / semi nars / workshops/ t rai ni ng courses/ l ect ures organi zed duri ng
t he report ing period and covered in a chapt er separat ely in t his report .
I t ook over as Direct or w.e.f. Oct ober, 2003 from Dr. K.V. Raghavan who served
as Direct or for 7 years w.e.f. Januar y 11, 1996. I proposed a road map for t he Inst it ut e
t o achi eve excel l ence i n i nnovat i on and di scovery dri ven research i n heal t hcare,
indust rial research, st rat egic mat erials, et c; our effort s are bearing fruit now and t here is improvement in Inst it ut es
overall performance. The year 2004-05 has been an excellent year for us, since IICT st ood first amongst CSIR labs in
Pat ent s Filed (62), Pat ent s Grant ed (56), Scient ific Papers Published (408) and Ext ernal Cash Flow (Rs. 18.5 crores). The
Inst i t ut e i ni t i at ed mega proj ect s (2003-05) duri ng t he peri od and pl ayed maj or rol e as nodal l aborat ory f or CSIR
Net work Proj ect s, (a) Developing Green Technologies for Organic Chemicals and (b) Globally Compet it ive Chemicals,
Processes and Product s. A separat e chapt er gives det ails of t he CSIR Net work Proj ect s.
In anot her maj or i ni t i at i ve, Gover nment of AP sought IICTs sci ent i f i c exper t i se and desi gn engi neer i ng
capabilit ies t o set up a Biot echnology Incubat ion Cent re (BTIC) at Genome Valley near Hyderabad. Depart ment of
Biot echnology (DBT) is also suppor t ing t he proj ect . Some of t he ot her maj or proj ect s under t aken and successfully
compl et ed duri ng t he per i od are: TBBA (Sol ar i s Chemi cal s), HFC-134a (SRF, Navi n), Haf ni um (NFC), DME (IOC),
Esfenvalerat e (RPGLS), Degumming of rice bran oil (TMOP), Gas Cracker PP (GAIL). IICT also at t ract ed maj or overseas
client s like Aisin Cosmos (Japan), Glaxo Smit hkline (UK), Du Pont (USA), Givaudan (Swit zerland) for cust om synt hesis
and ot her collaborat ive proj ect s.
The Inst it ut e creat ed t he maj or facilit ies such as (a) Cent re for Analysis of Chemical Toxins (CACT) wit h t wo
GC-MS and GC inst rument (b) Pre-Biot echnology Incubat ion Cent re (PBPC) and (c) High Resolut ion Mass Spect romet er.
In addit ion, a high pressure cat alyt ic vapour phase react or wit h dat a acquisit ion syst em and a high pressure bat ch
react or syst em was procured. Also, GC-MS & Trackphere at t he Pheromone Cent re, Table Top X-ray Diffract omet er
wit h aut o sampler & Ion Chromat ograph wit h a special feat ure of having on-line analysis were inst alled.
In brief, IICTs per formance during t he report ing period has encouraged us t o go for successful complet ion
of 10t h Five-year Plan Programmes. I acknowledge and congrat ulat e t he Business Management Division t o bring
out t he report t o t he current shape in t he short est possible t ime and t he excellent support provided by t he Research
Management & Informat ion Management Divisions and t he concerned R&D and ot her Depart ment s.
Hyderabad
March, 2006
(Dr. J.S. Yadav)
Di rect or
V VV VV
VI VI VI VI VI
Research and Management Councils
Members:
Dr. K. Nagarajan
Direct or (R&D)
Recon Limit ed (R&D Cent re)
Bangal ore
Prof. J.B. Joshi
Direct or, UDCT, Mumbai
Dr. (Mrs) Sheela Bhide, IAS
Pri nci pal Secret ary
Indust ri es & Commerce
Govt . of Andhra Pradesh
Hyderabad
Dr. M.G. Kulkarni
Dy.Direct or, NCL, Pune
Prof. S. Chandrasekaran
Indian Inst it ut e of Science
Bangal ore
Dr. S.K. Arora
President (Drug Discovery)
Lupi n Laborat ori es Li mi t ed
Mandideep, M.P.
Dr. A.K. Bhat nagar
Direct or (R&D)
Indian Oil Corporat ion Lt d
Faridabad 121 001.
Dr. G.N. Qazi
Direct or, RRL, Jammu
Dr. K V Raghavan
Di rect or, IICT
Permanent Invi t ee
DG or his nominee
Secret ary
Shri T. Suryanarayana
Technical Officer E II, IICT
RESEARCH COUNCIL OF IICT (2001-03) RESEARCH COUNCIL OF IICT (2003-05)
Members:
Prof. Ashut osh Sharma
Indian Inst it ut e of Technology
Kanpur 208 016
Prof. Mihir Kant i Chaudhuri
Indian Inst it ut e of Technology
Guwahat i 781039
Prof. Javed Iqbal
Di st i ngui shed Research Sci ent i st
Dr. Reddys Laborat ories Lt d
Hyderabad 500 050
Dr. Sumit Bhaduri
Head of Research
M/ s Reliance Indust ries Lt d
Mumbai 400 072
Prof. D.Balasubramanian
Direct or of Research
L.V.Prasad Eye Inst it ut e
Hyderabad 500 034
Dr. P.K.Ghosh
Direct or, Cent ral Salt & Marine
Chemi cal Research Inst i t ut e
Bhavnagar 364 002
Secret ary
Dept t . of Chemicals and
Pet rochemicals, Govt . of India
New Delhi 110 001
Dr. M.K. Gurjar
Sci ent i st -G
NCL, Pune 411 008
Dr. J.S.Yadav
Di rect or, IICT
Permanent Invi t ee
DG or his nominee
Secret ary
Dr.M.Vairamani, Scient ist G, IICT
Chai rman
Prof. R.Kumar
Jawaharlal Nehru Cent re
for Advanced Scient ific Research
Bangalore 560 012
Chai rman
Prof. R. Kumar
Jawaharlal Nehru Cent re
for Advanced Scient ific Research
Bangalore 560 012
O
O
O
O
O
O
O
O
O
O
O
O
O
O
O
O
O
O
O
O
O
O
VII VII VII VII VII
Members
O Dr.M.Vairamani,
Scient ist F
IICT - Hyderabad
O Dr. G.V.M.Sharma
Sci ent i st EII
IICT - Hyderabad
O Dr. B. Sat yavat hi
Scient ist B
IICT - Hyderabad
O Dr. D.Vijay Kumar
Sci ent i st C
IICT - Hyderabad
O Dr. B.V.S.K.Rao
Technical Officer B
IICT - Hyderabad
Members
O Shri G.Sampat h Kumar
Scient ist F
IICT, Hyderabad
O Dr. P.Shant an Rao
Sci ent i st EII
IICT, Hyderabad
O Mrs. C.B.Lakshmi
Sci ent i st EII
IICT, Hyderabad
O Dr. (Mrs.) A.L.Prasuna
Scient ist EI
IICT, Hyderabad
O Dr. N. Narender
Scient ist B
IICT, Hyderabad
MANAGEMENT COUNCIL OF IICT
(1-7-2001 t o 30-06-2003)
MANAGEMENT COUNCIL OF IICT
(1-7-2003 t o 30-6-2005)
Chai rman
Dr. K.V. Raghavan
Di rect or
IICT, Hyderabad
Chai rman
Dr. J.S.Yadav
Di rect or
IICT, Hyderabad
O Dr. Veena K Parnaik,
Sci.F,
CCMB, Hyderabad
O Shri T.Krishna Reddy
Sci.G,
IICT - Hyderabad
O Sr.F&AO(SG)/
Sr.F&AO/ F&AO
IICT - Hyderabad
O Permanent Invi t ee
DG or his nominee
O Member Secret ary
IICT - Hyderabad
O Shri Uday Rangrez
Tech. Officer E
IICT, Hyderabad
O Sr. FAO/ FAO
IICT, Hyderabad
O Permanent Invi t ee
DG or his nominee
O COA
Member-Secret ary
IICT, Hyderabad
Research Council Meeting in progress
VIII VIII VIII VIII VIII
Human Resource St rengt hs
IX IX IX IX IX
Human Resource St rengt hs
X XX XX
Applied Research Outputs
XI XI XI XI XI
IPRs Prot ect ion
XII XII XII XII XII
IPRs Prot ect ion
XIII XIII XIII XIII XIII
Publicat ions Record
XIV XIV XIV XIV XIV
XV XV XV XV XV
Financial Performance
Financial Performance
XVI XVI XVI XVI XVI
XVII XVII XVII XVII XVII
Performance Indicators Per Scientist
Performance Indicators Per Scientist
XVIII XVIII XVIII XVIII XVIII
Diamond Jubilee Celebrations
(August 5, 2003 to August 4, 2004)
yN \ oy z
ETo 5, 2003 - ETo 4, 2004
2
3
-t- |+t -t- + |- t + + -+t
| i + + |+ -t- -- -t-+t +
~+ s+tt +t - -t+t +t |-t- -t- +
|+t + |- -+ t+-t --t +t+-t- |-+t , +t
-~ + t + -- t- + --~ -- i
t+ + +t -t- + |- t- , 2003 ||=t -
- ||++t + t t:. t:. t. -t. t+ ++t
tt t+- .Apex) ||+ +t +- |++t ++ti 5
+-+, 2003 +t t+ + +t ttt +t =t = ti
-t|-+, t-+|++ tt|+ ++t +t t|- +-
t- + = + ttt + |- -t: +t-t +-t- +
+-+t-t- |--+ vt. +. t. t~- +t ++t 9
s-, 2003 +t |=t - - ||++t + +t + t
t+- .Apex) ||+ +t ++ :i t+- ||+ -
+ + -tt- -+ ++t +t t+t- |++t +t +t+ +t
s+|+ +t tt +ti vt ... +t- - 1 ++ + 2003
+t t+- ||+ .Apex) + + +t =t =t-t
+t t+ ++t ttt + s+- - |-t |
+- + |- -+ + +t +t t+t- |++ti t+ + +t
+ + -tt- t+t|+ ||=t ttt +t +tt
|---t-t
1. tv = +t ott t vt t - 5 +-+, 2003
t+ ++t .1944-2004) ttt +t =t=
|-. 5 +-+, 2003 +t t+ ++t -|+ |-- +
-t~ ti vt. ttt :-t-t, +,
|- +tt, t-t- -+t|+| i t: t: t -t
- |- +tt .t-t-), + t -t .-t+t-)
+t +.-.++t-+ .-t+t-) + t : -
+t-tt - -+t |++i +t + + t-+|++
+t++ tt -t ti
2. 'tn ot + n o otv= tv |=v = o vt=
|vto t=t +t =s-=-st= =s=t ' s t t=
o- n= - 30 +-+, 2003
|-|-v |-t- stt|++t s=t+ - =t+t+ +-
stt|++t ~.OTAI) .-|~ v-) + t -t-
=t +- t- t|-+ -t- |+t t+t
+t - - --t-- -+t+ - 30 +-+, 2003 +t +
|-t+ t-t+ --- +t t+t- |++ti vt.+.t.
t~-, +-+t-t- |--+, t:.t:.t.-t. - ---
+t ++t +ti + --- vt.+.-t. -t++t - t-
t- +- |---|-t-t +t t:.t:.t.-t. + +-
t s=t+ + =+- + +t |-+ |++t ++ti
t.t.t=-t:t t, t--t+ t, +|+ |=t+,
t s- +t - : --- +t -~t-- |++ti
-t..t.-t , =t+ +t --t- t++t
+ t 50 -- s|+ |-- -t- =t +- |-+t:-t +t
-t--t + +--|+ t- + st.|-.t- -+t +t + st
t :||-+|+ |-. + t t:. t:. t.-t. tt
-+t|+ t+ + rt + t--t+ t +t |-+ ++i
s -t t -t- =t +- t- ----t--
-+t+ t|-+ -t- |+t s|-+t -
|-t | |++t ++ti --- + +t + -tt-
-t- =t +- stt|++t t+- +t =t-tt
-+|-+ |=t |++t - ||- ++tt +++ ---
- |-t | |++ti |+--, -t- +: - st t |++t
| =+t-, + | + t-+, =t+ + t +t
t..t:.t., -: |-at tt + --- st+t|+
t -+ -- st -+-t-tt st.|-. -+: tt
- st+t|+ |++t ++ti vt.t.+t.-.st-, --|--+
+, |-|-v |-t- stt|++t s=t+ : ---
+ +t+ i
3. =tsv |o ott - 5 |+-+, 2003
-t- - t s- |-t- +t-t + t 5
|+-+, 2003 +t t: t: t -t t+ + +t +t-+
|- tt +t +++ t+t- |++ti ++
- st.-.-+|+, vt- ++--t t-, t: t: -t,
+t-- tt + | + |==t+~ |-+t ++ti st .-t.+ .t:
s+t, t--t+ |-, t.s. |-t- +t-t +t vt.
+- +. -|+, +-+ t+--, : t t, t+-,
-t+t- tt tt + |- -+t +t -t|-+ t+t |+
|++ ++i
tv = +t ott (t+ 5, 2003 5, 2003 5, 2003 5, 2003 5, 2003 o t+ 4, 2004 4, 2004 4, 2004 4, 2004 4, 2004)
4
4. |-t t t= o t vt -15 |+-+, 2003
t+- t |-t- + |+- - -+ |+t |--t
+ t-t+ +tt +t t+t- |-. 15.9.2003 +t
|++t ++ti st.t.+tt, +, t.s., t-+ -t
|t -|+- : tt + -+ |+| i +tt +t
st= st- |-++ t. t+ +t t + -t++
-- ti -+ |+| - -- =t+~ |--t +
t-t st+t+ =t+tt + |+t - t |-+t t
|--t |+t|+ +t +- + |- -t|-+t +t
t t- |++ti vt . s+t t. |-t- - +t t + -t|-+-
+t -t-- |++ti
-t|-+- vt.+.t. t~-, +-+t-t- |--+,
t:.t:.t.-t. - -t-|+ =t+t+ t+ t+~-
t +t |-t t vt. +- :.--, |--+,
t.vt.+.vt. - -+ t-t |+ +t- + -= t+-
t |-t- + |+- |++t - -t|-+ -
s-++ |++, |-+t |+t|+ t-t +t +:i
vt.vt.-t, -t|-+, t:.t:.t.-t.- ++-t
= vt~ +t- s+- + |-+ |+ | |++ + |- + -+
t--, + t|-+ -- t vt. t-~t --t,
-t|-+, t:.t:.t.-t. - +t|+t - |< t+-
+tt-t |++t - -t|-+ - s-++ |++i vt.
t.+.t, -t|-+ -.t.t.t:., vt.t.+. -+-t,
-t|-+ -.t.t.t: .t vt +t +t -tt, -t|-+,
-. t:. t, +tt t|- - =t -t|-+ - - s-++
|++i -t|-+t - -- -t tt t+- t
|-t- + + |+--t - --t +t t |--t + t+
t+- t |-t- +t |+-- +t+ +v -+
t+tt + t- - +t +t| +ti
+ t-+|++ +t++ +tt +t- -t+
t-+ -t-+ +t -- |++t ++ti
5. vt v t ||v-ot vt |v s| = s
+t t= o- n= - 19 |+-+-20 |+-+, 2003
t: t: t -t, t: t - +t + - =-,
-t: tt +++ -- t+t|+ + --- 19-20
|+-+, 2003 +t t: t: t -t ti t+ +
-t- - ++t, +t-t --+, |-|+-+, |t|+t
t +-|++t - : - -- =t+ |-+ti vt .t.+ . +t +t- ,
- + --|+, +t++t+ ||t-+ - - -- +t - t--
|++ti -- - ~t-- =t+~ st . +t +t- - t + |+
+ |- vt + -t-tt|+ t +t + |+t +t t+++t
- t -+ +t |+ :-| + +t~ st-t- =t+ |
+t +-+ +-t t ti vt. .t+t) : t|t, |--+,
+t - - ~t-- tt +t ++t +ti vt + -t
t+ |+t + -+ t +t++ ||- ++tt -
vt +-t t+ |+t + :|+t t= + vt +-t
t + t-+t+~, vt + -t -+ - t |-+- +t |+t, vt
+ -t t +t +t t - + s+ |++ --t-t =t-tt
++, - + |++t - -- - =t +t t-t- s-t- |++ti
vt...t, - |--+, st+|++ --t- s=t+ - vt
+-t t+t + -t|-+ |+t + -t|-+ -<|++t +
-+t+ - =t+~ |-+ti --- +--t+ : ---
-|--t --- + -t++ + -tt- t+ ++ -+
- -t - |-t | |++t ++ti : - -- + | +-t
vt. t t, =+- t+ |-++ +, vt.+.t.
t~-, |--+, t: t: t -t, st. --t-t -t-,
t ++ st+, vt .. .t. +, st+ |++ --t-
s=t+, t: t: t -t t|- t|- i + -|+
|-~+ |-+t ++t |+ |-|+-t -tt + |-|+-t+ --
|++ =t+ +t r- +t |-t +t+ +-t -+|+
t++ i -t |-+ +-t +t --t - ++ ||=t
-+t - |- +~t-+ t-+t +t -t--t +- - |+
t |-+t ++ti : - -- + - +t + vt . ..+t-,
t.+ .t.t.. |+ t vt . s+t t. |-t- i
6. tr tr ot t tv = +t unt - 21 |+-+,
2003
vt.t..t-+, t|--+, t t: t
|-, vt t: t .=t+ +t) - 21 |+-+,
2003 +t t: t: t -t t: t: t -t t+
+ +t -t +t - ~t-- |++ti st . t. + t +,
t: t: t -t - t- -|+- - tt +t ++t
+ti |--- +t++ --t
O - --<t|+ -+ =- -: - t- s+t +t-tt
+t -~t--
O tt+|-+ -~--t |-+~ +: +t -~t--
Biennial Report 2003-2005
5
O t: t: t -t -| +t -- -tt-~ +t
|+t+~ +t -~t--
O -| +: +t -~t--
O t: t: t -t t- t- |+t s- +t
|t--
O t: t: t -t +-t|+t t tt +t t+
++t -|+ |--t +t |+~
O t s- + t vt+-t-, t.-t.. +t|-t-
tt t+ ++t -t+ |+ vt+ |-+t+ +t
|t--i
O vt.t.. t-+ tt t+ ++t |==t+~i
O vt.+.t. t~- +t s-+|+ -+t t: t:
t -t +t + |+ti
O -t|-+ - s-++t+~
7 ot.o.tr .t. tts=t |o - 26 |+-+, 2003
|-. 26 |+-+ 2003 +t -t- - -t|-+
tt|++ -t- -|+- -t--t |- -t+ti :
- st . t: +-t v vt, -+ --|+, t-t-
-- ||t-+, -t+t- -t--t+ |+| i
tt +t s +t+ |---t-t -
O -t- |--+ tt +t+ =t+~
O stt|++t +t+- |=+---tt +t -t~
O 25 + +t t t|-+ - +-t|+t +t -|+
|-- s-t- +-t
O t |--+ +-t|+t +t -t-
O +|- / | t tt +t - t- - s+t-
- --+t
O t + + |- vt. t. -. t -t+
--+t, t+ + |- t +t-t-+~ t
--- -t+ --+t
O |+-, |--t-t + tt+|-+ stt|++t
|t|+t + |- st~- +-t|+t + +-tt,
|-t- =t+t+ stt|++t+ -t- .IIT) s
st-+ |++t, + |- t|-+t +t ~t+~t
O +-t|+t + +-tt, |-t- +t| +t -tt
+t- -t|-+ -ttt s-++ 90% =t
-+t-t + st-+ |++t , + |- -+- --+t
t: t: t -t t+ ++t - --+t tt
+t t+t- =t : - |++t ++ti t. -
++, =t+t+ |++- -t + =+- --+, : +t++
+ -+ |+| i -+ |+| - -t- + -+
|-t|v+t +t --+t s-t- |++ti
8. v.t. vt==t ttv t - 6 +++, 2003
+- t + -t- |+t + |- vt.
-t++t + +t+-t- +t -+ - <t-t -- +
--+ -+ -|-- - =t+t+ +-|-- -t|-+
~ - s|+ + -t+ =t+~ t+t|+ +- +t |-~+
|-+t i t: .t: .t.-t. s t+ 6 ++ +, 2003 +t
vt.+.-t. -t++t + ~|- +t+t vt. -t. . =t+,
= +- |-- + t.t..+t. - vt + .-t. -t+ +t -t+
=t+~ |-+ti vt...+t- - s|+=t|++t +t -t++
|++t t t+t+~ +t ++t +t -|-+ |-+ti vt.+.-t.
-t++t + t- -+ t+t+~ +t -|-+ +t+t
++ti
vt. +t+vt -- -t++t +t - 6 +++, 1923
+t +|--tv + +t|--|+- +t t ti |~+
-+ st|-+ + --t+ + 1950 -t- s+t+t-t
+t+=t =t-t +t + 1971 ++ -t- v i
- |--+ +t +- t s=t+ + + + --
-t- |-|-v t+-t- stt|++t -t|-+t +t
+t +- +t st-t|+ |++t t : -: |-t -ti vt.
-t++t +t -+ t-t+ +t-t+ --+tt
-t|-+ |++t ++ti 5 |+-+, 2002 +t vt -t+ +t +t
|-- ti =t+t+ tt+|-+ stt|++t -t- +
-+ =- +t ---<t|+ -t +- vt.+.-t. -t++t
|+ + -- -t|+ |++t ++t, |+t -=+~
vt.-t..=t+, -t-+ |--+, t t +t -
-~t-- |++ti
9. t+t= tot=|=v st t |vt o tt= tts=t |o
|t - 7 --+, 2003
-..t. -+t+ + -t- t+t t+ |--t-,
|-|+-t |-+~ +t s-+ tt|+ -+-, |++
tv = +t ott (t+ 5, 2003 o t+ 4, 2004)
6
- vt.t.-. -t-, + - ||- st+,
-|-|+-+t+ -++t+ --t- +:, + +tt -t t
|-|+-t |-t- -t-, --+ tt +t 7 --+,
2003 +t |==t+~ |-+t ++ti vt...+t-, + -
|--+, t:. t:. t.-t. - tt +t ++t
+ti
10 s=t t= ot==tt s = = tvt t= s|
vt= tnt - 10-15 --+, 2003
+ +t+t-t 10 --+ 15 --+, 2003 ++
:i +--+t t+ +:, |-at tt st+t|+ -+t~t+
t+-t- - + ttt+ +t+t-t--s|~
-t++ =t+ +t + -vtt -t t-+t,
++-t- +t --t- +t |~ ++--t + |- t+t|+
|++t ++ti =t+ 12 +t t-+t 4, ++-t-
1 +t --t- 1 s|+=t+t, +- 18 s|+=t|++t - :
+t+t-t =t+ |-+ti
15 --+, 2003 + t t-- tt
vt...+t-, |--+, t:.t:.t.-t., - s|+=t|++t
+t st~ - s-+ + |++ i vt ...t-, | +t+ +
|+- -t|-+, +--+t, -: |-at : tt +
-+t|+| i vt..|~, - |--+ +,
|-+~t-+ t+- t- s=t+ - -t ++ +t |-+
-- s-++ |++ti
11 st s|v r v= o r v= v t - t t= o- n= - 4-
5 |--+, 2003
4-5 |-+, 2003 +t t+t|+ |-t, +-
-t--|+ +t -tt+ t-+ tt -st+t|+ |++t
++ti vt.+.+t..st-, +, +t+-t, + +t
s=t+, t:.t:.t.-t., -t+t- - --- +t -+t
+t |-+ -|-+ |-+ti t+ -|- + , +t+ - - -
+ +-+ -+ + s|+ -+t : t-+tt + +t~ :-
+-t stt|++t - =t -+t+ + -t--|+ +t
--t-- + + -- |+ -- t- +|+
+-t t i -t|-+t t --t-+t + --t+t
+ |+ t :- s+ s~t-t +t st-+ |++t t+, t
tt-+ -+ +t --+t - |-++ + :-t +t
-t+t + t -+ -t - :- +-t :-+-tvt tt
+~-t t++t t:vt- +++ + |-~ +t
--t + + +t|+ :- +-t |+-t =t -t-t -
-- +t t +i vt..-+, |--+, =t+t+
st t |++t -t-, -: |-at tt : |-t +t - ~t--
ti vt...+t-, |--+, t: t: t -t - :
-~t-- tt +t ++t +ti
12. =t= v-t ttv |v v =t -12-14 |--+,
2003
: --t- |---|-|+ -tt - =t+ |-+t
O --t stt|++t |=t+
O -t|=+t+ :- |-, -t+t-
O |-t- stt|++t |=t+, -: |-at
O -+t~ - |=t+, -: |-at
O t- :|v+t t..t:.t.-t
O =t+t+ t |-t- |=t+, -: |-at
O :-+-t|-+ +t-t- t+ |-|-v, -t+t-
O t..t:.t.+t -t+t- |-+ s+t+t-t
12 |--+, 2003 +t : - -t - + - ~t-- tt
+t t+t- |++t ++ti
vt...+t- - : tt +t ++t +t t
t t+ +t t, st- |-++ - ||=t |++-
-tt +t -t++ |++ti |++- - -t |--t ++ --i
-+t~ - |=t+, -: |-at : --t- +t |+t
ti t-- tt +t t+t- +v -t- - |++t
++ti t. t+ +t t, +t+ - -+t- s-++
|++ti
13. v | v |a-+t s s t+t= +t t=
o- n= (tr tr ot tr - 03) - 18-20
|--+, 2003.
t: .t: .t.-t. + tt |--+ 18-20, 2003
+t t+t |+ |++t ++t +t t: .t: .t.-t., t: .: .: .: .
|---, - v t:+- |-+ t t:-t .+ ...) --t
s+ + +t-t+ ~ .t--|-+t), t: t s
.---v) +t t+- +--+|-+ - | ~ .t-t-)
7
tt + - -- s+t |+ ti vt . ..+t-, |-- +,
t:.t:.t.-t.- : --- +t -~t-- |++t t
+| +|<-+t +t |=t t :+t -+t|++t -
s+t vt-ti +t- |-t+ --- 18 t + -tt-
126 - s-+ + |++ ++ i ++t +--+ |- + +t ++t : + |-+
++ t++~ +t +-: +- t ++ -t|-+t -
:- =t+ |-+ti
14. vt .st.o. |+ ttv t +t tot=|=v
|=t |vt s tr .tr .ot.t. tv = +t
o |=t - 10 -t, 2004.
-t- + tt+|-+ |=+t |+t s=t+ - tt+|-+
|=+t|+t-|+ --t|++t |++ - + |-t+
t-t+ |-t 10 -t, 2004 +t t+t|+ |++ti
: |-t + t+t- +t -+ --+ t+, t-t+
s+t+t-tt +t |+ -t-t +t++ tt+|-+
|=+ +tt + +t- |-tt +t t-t- s-t- t tt+|-+
|=+t|+t + t|-+ -t- |+t +
-+- - t-t t-t -+tt - |-t |
+- + |- + - -- +t-t ti |-t -++
-s+++ +t+|++t, |=|++t |=+t|+t tv|-+
+t | - -, -t- -t --tt +t +t +t s+ t
+ t|-+ :-+t|- |++t - ti : |-t +
++-t+t tt+|-+ |=+t|+t + ||=t
|+-t tt t|+ =t+~ t+t|+ |++ ++i 8 t
-t. . |+ -t+ |==t+~ vt.vt.. |-t,
||- st+, |-tt ||t-+, +t-|-++t, +
- |-+ti
15. vtt r + |vo v t t |v =s=t +t v-=
ot=v t v |v tr=-t t= v t= tnt
12-17 -t, 2004
-t- - -t++ |++ - 12-17 -t, 2004
+t |-t+ t-t+ +t+t-t +t t+t- |++ti
t + 13 |+ -t-t 13 t t- t+
s+t+t-tt 4 s|+=t|++t - : =t+ |-+ti
t+-t-, t |-t-, tt+|-+ :t|-+|+ +t
|-|+-t t|- ||=t t +t+ +-t- s|+=t+t
: |-t t|- i =t |--t ++ t~|+
tv|-+ + +tt|+ <t|++ --t -
s+t vt-t ++ti : +t+t-t -+ +t+ + t +t
s|+-+- .-v - t-) -|-+ - |+ +t- |-+t ++t
t s|+=t|++t +t =t t+-+ t. vt. + --
|+|+ |++ ++i
16. t t= |zt= |o ott - 28 +t, 2004
t s- |-t- stt|++t -|+-, -t+t- +
+t+ 28 +t, 2004 +t + tt t+t|+
|++ ++i t t t- tt t- s=t + -+~
+t ~t+~t +t -|+ s-++ + t-t+ |-t- |-
tt +t t+t- |++t t+t i vt.-t. tt t,
-t+t, |-t- st t |++t +t -t |t : tt
+ -+ |+| i st . t. +t t, +, t s-
t-+ -t |t -|+- - : tt +t ++t +ti
17. 12 t t |+ t=s ttv |t - 1 s-,
2004
vt. .t+t). t, |-t- stt|++t t
+t -t+t, =t+ +t - 12 t t |+ --- -t+
|==t+~, 1 s-, 2004 +t |-+ti vt. t - +t+
-=|+ +t t +|++t - t- + +t- |+ +t-
stt|++t t-+t +t +t-tt+~ |++
- -+|+-t++ |==t+~ |-+ti ++ +vt -+t
-t|-+, ||t-+ + +t-+ t +t -+
-t- + -t+t - =t+~ +t -t.
18. t t= st t |vt |o - 11 :, 2004
+ 11 : 1998 +t =t+ - -t- -t~ -t~
|++ +t -t~ +-+ --++t st-+ + -ti :
|- +t s-++ + t-t+ stt|++t |- + --
-t+t t+t t t:.t:.t.-t. =t s-++ + :
|- +t -t+t i : + stt|++t |- =t+~,
vt..+t. ttt, =+- |--+, t:. t:. t. -t. -
|-+ti t:..t. +t+t + t + t|-+ +t =t
t+t- ti
19. =-v v+t vt +nt - - - - - - - - - - |=tnt s
o |=t 4-5 -, 2004.
- - |+t--t .Virtual Reality) + +
tv = +t ott (t+ 5, 2003 o t+ 4, 2004)
8
+t-tt -+ t: t |-+~ +t vt:-
+|+ ++ |+t t i -- |+t--t + =+t
: stt|++t |+t |-++ +t +t -+t+ -+=+
=t -t|-+ t t+t i |+ =t : +t |+t
|++, -t- +t +|+ ++ t t|+ t
|-+|+ tt|++ -+t+ ++ :+t -t+t =t +-t
-| i
: |-t +t --+ tt-+ -+t ++ :
stt|++t +t --t- +t =t-tt - |-t +-t
+t -t- |+t -t-, |+ -t-, t,
t+ +t +t + t - t + - +tt |+t
+ |+-t +t s+t++tt + +t- |-t | +t-t
t i
vt . t. -. | , |-- + + v -t|-+, -.t.t.
t:., -t+t- - : |-t +t -~t-- |++t i :
|-t 5 ++-t+ t|- i : t|+
|==t+~t + t-t 21 - s-++ |++ ++ i
t:.t:.t.-t. tt tt+|-+ t+ --
|+|--t + -+t+ - - s-++ |++ ++ i
20. 14t |oa |zt= |t - 2 -t: 2004
st. . +. +-tt, |--+, t-t|+ +
t |-t-, -: |-at - --t, |--, :+|-+
=|+t~t |-|+-t |++ - +t, 2 -t:,
2004 +t .+t.t-, -.t.t.t:. --- tv,
-t+t- |==t+~ |-+ti
+ 1981 vt.t..|< -t--t -+t +t t=
-+ :- |t t +t |++t tt |++t ++ti : -+t
+ |++t+-t-t + + |+ -+ - |-- -
-t|-+ |++t - ||- -t|-+t tt |==t+~t
+t t+t- t+t i
21. tr .tr .ot.t. tv = +t ots= ott -
4 +-+, 2004
=t+t+ tt+|-+ stt|++t -t-, -t+t-
t+ ++t t-- tt +t t+t- 4 +-+,
2004 +t ti t. +|-- |+-, t--t+ t-+ t
.-+ -t), |-t- stt|++t +t : |+t,
=t+ +t +t -t+, t..t:.t., :
tt + -+t|+| i
t. |+- - -- t+ ++t |==t+~ +t
|+ t..t:.t. +t 21 | -t stt|++t+ +t|+
+t t+ +-t-t i stt|++t+ -t+~t +t +t +t
--t- +t =|+ - stt|+|++t +t s+t+t-t
+tt -t- + |- + |++t +t+ +t -t|-+
-t+ =t|++t |+ t++ i t. |+- -
-t|-+t tt- |++t |+ +t+t t -t-
-+=+ 70 +tv =t+t+ -+t + |-+ =t-, tt
+t --+ t +t +t+i
vt.t.. t-+, t|--+, t..t:.t.
- +t |+ |-t- stt|++t - - t-t+
+t+ |++t +t t..t:.t. t-t -t- t-
+ -t+ t:.t:.t.-t. - t+-t- +t tt+|-+
stt|++t + --t --~ -t- +-t |-+t i
-t- + 2005 t= t- t- --- t- + -=
- -t- --t-t +t t+++t - +- |-+ti
t= vt...+t-, |--+, t:.t:.t.-t. -
-t|-+t, |--|-t|-+t, |+ -t- t+ +
--+t +t t:.t:.t.-t. + +-t|+t +++ ++
=t +t -t++ |++t t -t+t- + |-t + +t-
tt -t- + t= -+ + 1989 =t+t+
tt+|-+ stt|++t -t- + -- -- -t|+
s+t+t-t + |+t +t + 1994 +t -~ + +t
++ +t +tt - s+t vt-ti : - t +|--
|+- - -t|+t +t |t -- |++t t t: .t: .t.-t.
+ t|--+ +t++ -t|-+t +t -t-- s-t-
|++t i -+ =+- |--+t t:.t:.t.-t. +
+t+t - s+t+t-t + t -- +t +t+ -
s+t vt-ti vt ..t.+ . |-- + + v -t|-+ - -+t-
s-+t s-++ |++ti
t--t+ t t - t:.t:.t.-t. t+ ++t
-t+ +t - ~t-- |++t t : - + -t +t
t-~ |++ti -t- t stt|++t +t t s|| +:
+t t -t t v-+ -t~ s+t+t-t +t =t -~t--
|++ti t- t |+|+ - -t |-|+- |-t- s+t +t-t,
+ +t-t:- |t +t st+|++ --t- t+-t-
s+t+t-t +t =t -ti
9
Si xt y year s i s a l o n g p er i o d i n t h e l i f e o f an R&D
i n st i t ut i on . It i s a momen t ous occasi on w h en t h e
i nst i t ut i on has t o p ause t o recal l t he st ruggl es and
ef f ort s of i t s f oundi ng f at hers and t hose who have
co n t r i b u t ed i n man y w ays t o t h e g r o w t h o f t h e
i nst i t ut i on.
To cel ebrat e t he Di amond Jubi l ee, an IICT Di amond
Jubilee Celebrat ions Apex Commit t ee was const it ut ed
i n t h e mo n t h o f Mar ch 2003 al o n g w i t h var i o u s
subcommi t t ees. Curt ai n rai ser ceremony was hel d on
August 5, 2003. The Apex Commi t t ee al ong wi t h t he
Chairmen of various Sub-commit t ees first met on April
9, 2003 under t he chairmanship of Dr.K.V.Raghavan, t he
t hen Di rect or, t o draw a t ent at i ve pl an f or year-l ong
cel eb r at i ons cover i ng sci ent i f i c, cul t ur al and soci al
event s. The Apex Commit t ee met several t imes during
t he year and revi ewed t he progress. Dr.J.S.Yadav t ook
over as Chairman of t he Apex Commit t ee on 1
st
Oct ober
2003 an d h el d sever al meet i n g s t o d i scu ss t h e
arrangement s of t he Diamond Jubilee celebrat ions. The
various event s conduct ed during t he diamond j ubilee
year are out lined below:
* Curtain Raiser - August 5, 2003 Curtain Raiser - August 5, 2003 Curtain Raiser - August 5, 2003 Curtain Raiser - August 5, 2003 Curtain Raiser - August 5, 2003
The Curt ain Raiser for t he IICT Diamond Jubilee (1944-
2004) Celebrat ions was held on August 5, 2003 and t he
IICT Di amond Jubi l ee l ogo was unvei l ed. Dr. Masami
Inada, President , M/ s Aisin Cosmos, Japan was t he Chief
Guest . IICT signed agreement s wit h M/ s Aisin Cosmos
(Japan), KCP (Hyderabad) and K. N. Biot ech (Hyderabad)
on t his occasion. A cult ural programme was held in t he
eveni ng.
* Independence Day Indoor Sports Independence Day Indoor Sports Independence Day Indoor Sports Independence Day Indoor Sports Independence Day Indoor Sports - August 15, August 15, August 15, August 15, August 15,
2003 2003 2003 2003 2003
The Independence Day IICT Di amond Jubi l ee Indoor
Sp o r t s meet f o r t h e emp l o yees an d t h ei r f ami l y
memb er s was hel d and t he f ol l owi ng event s wer e
conduct ed :
O Badmint on (Men & Women)
O Carrom (Men & Women)
O Table Tennis (Men & Women )
O Chess
O Track and field event s for t he resident s of t he
st af f quart ers
* National Seminar on National Seminar on National Seminar on National Seminar on National Seminar on Recent R & D Trends Recent R & D Trends Recent R & D Trends Recent R & D Trends Recent R & D Trends
in Rice Bran Oil Processing and By-Product in Rice Bran Oil Processing and By-Product in Rice Bran Oil Processing and By-Product in Rice Bran Oil Processing and By-Product in Rice Bran Oil Processing and By-Product
Utilization Utilization Utilization Utilization Utilization- August 30, 2003 - August 30, 2003 - August 30, 2003 - August 30, 2003 - August 30, 2003
Lipid Science & Technology Division along wit h t he Oil
Technol ogi st s Associ at i on of Indi a (Sout hern Zone)
organized a one-day Nat ional Seminar on Recent R&D
Trend s i n Ri ce Br an Oi l Processi ng and By-p r od uct
Ut i l i zat i on on Aug ust 30, 2003. Dr. K.V. Rag havan,
Direct or, IICT presided at t he seminar. The seminar was
dedi cat ed t o t he memor y of Dr.K.T.Achaya a wel l
known oil t echnologist and former Head of Oils & Fat s
Di vi si o n o f IICT. Sh r i V.So b h an ad r eesw ar a Rao,
Honourable Minist er, Depar t ment of Agricult ure, Govt .
o f An d h r a Pr ad esh i n au g u r at ed t h e semi n ar. The
Honourable Minist er also handed over agreement s of
MoU signed by t he IICT wit h Ganapat i Solvex Pvt . Lt d.,
Raj nandgaon and Mecpro Heavy Engineering Lt d., New
Del hi for t he est abl i shment of 50 t onnes per day ri ce
bran oil refineries wit h t he grant -in-aid assist ance from
TMOP & M, Govt . of Indi a. The f i rst t wo sessi ons were
devot ed t o t he discussion on t he recent R&D t rends in
ri ce bran oi l processi ng and by-product ut i l i zat i on. A
dist inguished panel of speakers discussed t he various
t opics relat ed t o prospect s of rice bran oil t echnology
upgrading during t he t hird session of t he seminar. The
semi nar w as sp onsor ed b y Technol ogy Mi ssi on on
Oilseeds, Pulses and Maize, Minist ry of Agricult ure, Govt .
of India and Council of Scient ific & Indust rial Research,
DIAMOND JUBILEE CELEBRATIONS (AUGUST 5, 2003 TO AUGUST 4, 2004) DIAMOND JUBILEE CELEBRATIONS (AUGUST 5, 2003 TO AUGUST 4, 2004) DIAMOND JUBILEE CELEBRATIONS (AUGUST 5, 2003 TO AUGUST 4, 2004) DIAMOND JUBILEE CELEBRATIONS (AUGUST 5, 2003 TO AUGUST 4, 2004) DIAMOND JUBILEE CELEBRATIONS (AUGUST 5, 2003 TO AUGUST 4, 2004)
During the curtain raiser, seen from left to right : Dr. J.S. Yadav,
Director, Dr. K.V. Raghavan Ex. Director & Dr. M. Inada
10
New Delhi and co-sponsored by M/ s Muez Hest Process
Technol ogi es Pvt . Lt d., Mumbai . The convener of t he
seminar was Dr. R.B.N. Prasad, Deput y Direct or and Head,
Lipid Science & Technology Division.
* Teachers Day Celebrations - September 5, Teachers Day Celebrations - September 5, Teachers Day Celebrations - September 5, Teachers Day Celebrations - September 5, Teachers Day Celebrations - September 5,
2003 2003 2003 2003 2003
The IICT Di amond Jubi l ee Teachers Day Cel ebrat i ons
wer e or gani zed j oi nt l y b y IICT and AP Akad emi of
Sci ences on 5t h Sept ember 2003. A speci al t al k was
delivered by Prof. N.Sat yamur t hy, Dean, Facult y Affairs,
IIT, Kanpur and sci ent i fi c sessi ons were conduct ed for
t he benef i t of st udent s by Prof. P. K. Sai Prakash, Hon.
Secret ar y, A. P. Academy of Sci ences and Dr. Rat an F.
Toorkey, Polymer Chemist , EMRC, CIEFL, Hyderabad.
chi l dr en and memb er s of st af f who p ar t i ci p at ed i n
various Hindi compet it ions. A scient ific Nat ional Seminar
i n Hi ndi Rasayan evam j eev vi gyan ke ant ar b i ndu,
organi zed i n connect i on wi t h t he Di amond Jubi l ee of
IICT was inaugurat ed by Prof.C.Subba Rao, Chairman, A.
P. St at e Council for Higher Educat ion. About nine papers
were present ed in Hindi support ed by mult i-media done
i n Hi nd i . Dr. S.E.Hasnai n, Dr. K.V. Raghavan, Dr.Usha
Gosw ami , Dr.An n ap ur n a, Dr.V.K.Rao, Dr.V.K.Saxen a,
Dr.Ishrat ullah Dr.D.Shailaj a were some of t he scient ist s,
who present ed t heir papers in Hindi. Some of t he t opics
p r esent ed i n t he semi nar wer e : Chemi st r y Bi ol ogy
Int er f ace, Tradi t i onal Indi an Drugs, Gl obal i zat i on-New
Dimensions, Cell-A Chemical Fact or y, Pest Management
in Groundnut wit h Cont rolled Release of Polymers- New
Di mensi ons. The programme concl uded wi t h a Hi ndi
comed y Beemar Koun st ag ed b y t h e st af f of t h e
Inst i t ut e.
* Hindi Day Celebrations - September 15, 2003 Hindi Day Celebrations - September 15, 2003 Hindi Day Celebrations - September 15, 2003 Hindi Day Celebrations - September 15, 2003 Hindi Day Celebrations - September 15, 2003
On t he occasion of t he Hindi day, celebrat ions t ook place
on Sept ember15, 2003 in collaborat ion wit h CDFD. Prof.
Mu ku l Ch an d Pan d ay, Memb er, Hi n d i Ad vi so r y
Commit t ee, Home Minist ry, Govt . of India was t he chief
guest . Dr. K. V. Raghavan, t he t hen Di r ect or of IICT,
wel comed t he gat heri ng. In hi s wel come address, Dr.
Raghavan out lined t he Hindi language implement at ion
act i vi t i es i n vo l vi n g sci en t i st s an d ad mi n i st r at o r s.
Dr.Syed E. Hasnain, Direct or, CDFD appreciat ed t he st eps
t aken b y b o t h t h e In st i t u t es an d su g g est ed t h e
scient ist s t o writ e scient ific art icles in Hindi. In his Hindi
Day message, Prof . Pandey suggest ed vari ous si mpl e
st ep s t o f ur t her t he i mp l ement at i on of t he Of f i ci al
Language. The chief guest gave away t he prizes t o t he
* International Seminar on International Seminar on International Seminar on International Seminar on International Seminar on Global Scenario of Global Scenario of Global Scenario of Global Scenario of Global Scenario of
Herbal Medicine Herbal Medicine Herbal Medicine Herbal Medicine Herbal Medicine - September 19 - September September 19 - September September 19 - September September 19 - September September 19 - September
20, 2003 20, 2003 20, 2003 20, 2003 20, 2003
The semi nar was j oi nt l y organi sed by IICT, IGNA and
Max Mul l er Bhavan, Chennai at IICT on Sept . 19 20,
2003. Th e semi n ar r ecei v ed g o od at t en t i o n f r om
r esear ch er s, acad emi ci an s, med i cal p r act i t i o n er s,
st udent s and indust rialist s from t he Pharma sect or. The
semi n ar w as i n aug ur at ed b y Dr. C. K. Kok at e, Vi ce
Chancellor, Kakat iya Universit y. In his inaugural address
Prof. Kokat e st ressed t he need for t he development of
herbal-based medicines for t he benefit of t he societ y,
which India once pioneered in ancient t imes. Dr (Mrs) E
Teachers Day Celebrations at IICT
The Chief Guest is welcomed during the Hindi Seminar
11
Rahi mi , Di r ect or, MMB p r esi d ed over t he i naugur al
funct ion. Prof. Hermann PT Ammon, Professor Emerit us,
Pharmacology and Toxicology, Universit y of Tuebingen,
Germany delivered a keynot e lect ure Boswel l i a serrat a
f r o m an ayu r ved i c med i ci n e t o a mo d er n d r u g -
p har macol ogi cal and cl i ni cal st ud i es and gave an
excel l ent exposi t i on on t ransf ormat i on of Boswel l i a
serrat a t o a modern herbal drug t hat is clinically proven.
Eminent speakers drawn from various sect ions involved
i n t h e h er b al d r u g s d evel o p men t sh ar ed t h ei r
experi ences on di verse t opi cs st art i ng from hi st ory of
herbal drug devel opment , st andardi sat i on of herbal
medicines, development of herbal nut raceut icals, safet y
of t he herbal drugs t o opport unit ies in nat ural product s.
Dr J.M Rao, Deput y Direct or, Nat ural Product s Division
of IICT gave a lect ure on applicat ion of scient ific met hods
t owards scient ific development of herbal medicines. The
semi n ar w as f o l l o w ed b y a p an el d i scu ssi o n t h at
deb at ed key i ssues rai sed duri ng t he course of t he
seminar. The panel of expert s included, Dr Sanj eeva Rao,
Ex-Drug Cont roller, Dr. K. V. Raghavan, t he t hen Direct or
of IICT, Prof. HPT Ammon, Emeri t us Professor, Dr T.S.S.
* IICT Diamond Jubilee Initiatives - September IICT Diamond Jubilee Initiatives - September IICT Diamond Jubilee Initiatives - September IICT Diamond Jubilee Initiatives - September IICT Diamond Jubilee Initiatives - September
21, 2003 21, 2003 21, 2003 21, 2003 21, 2003
Dr. R. A. Mashelkar, Di rect or General, CSIR & Secret ar y,
DSIR (GOI) i naug ur at ed t he IICT Di amond Jub i l ee
Init iat ives on Sept ember 21, 2003 at IICT. Prof. R. Kumar,
Chairman, IICT Research Council presided. Some of t he
highlight s of t he funct ion are given below:
O Inaugurat i on of new research l aborat ori es i n t he
renovat ed main building
O Inaugur at i on of t he i nci d ent cont r ol cent r e f or
chemical accident mit igat ion
O Inaugurat ion of reforest at ion and green belt ing of
IICT campus
O Launch of ENVIS cent re
O Release of IICT HRD Document
O Present at ion of Diamond Jubilee Mement os t o IICT
st aff and research scholars
O Release of IICT special post al cover commemorat ing
t he diamond j ubilee of IICT by Shri T. S. Govindraj an,
Chief Post Mast er General, A. P. Region
O Diamond Jubilee address by Dr. R. A. Mashelkar
O IICTs evolut ion in six decades by Dr. K. V. Raghavan
O Sci ent i fi c present at i ons
Dixit , Consult ant , Pharmacology Evaluat ion and Dr. J.M.
Rao, Head , Nat u r al Pr od u ct s Di vi si o n , IICT. I t w as
unanimously accept ed t hat it is highly essent ial t o work
t owards underst anding t he t herapeut ically act ive part
of med i ci nal p l ant s. A gr eat emp hasi s was l ai d on
est ab l i sh i n g an al yt i cal st an d ar d s at var i ous l evel s
wit hout deviat ing from t he philosophical concept s. The
Co-ordinat ors of t he seminar were : Dr. J. S. Yadav, Shri
K.V.R.S. Murt hy and Dr. Prakash V. Diwan of IICT.
International Seminar Global Scenario of Herbal Medicine
Dr. R.A. Mashelkar, DGSIR is presented with the special postal
cover released on the occasion of Diamond Jubilee
Diamond Jubilee Celebrations (August 5, 2003 to August 4, 2004)
12
* CSIR Foundation Day - September 26, 2003 CSIR Foundation Day - September 26, 2003 CSIR Foundation Day - September 26, 2003 CSIR Foundation Day - September 26, 2003 CSIR Foundation Day - September 26, 2003
a. This was celebrat ed on Sept ember 26, 2003 at IICT.
The Guest of Honour was Prof.Y. Venkat arami Reddy,
Vi ce Chancel l or, JNTU, Hyd er ab ad . Some of t he
highlight s are given below:
O President ial Address by Direct or, IICT
O Unveiling of Biot echnology Incubat or Designs
O Pr esen t at i o n o f memen t o s t o st af f memb er s
complet ing 25 years of service
O Honouring of ret ired st aff members
O Research papers publicat ion awards t o JRF/ SRF
O Dr. R. N. Sar ma Memor i al Award f or JRF and Shr i
Gopalakrishna Rao Vepachedu Memorial Award for
SRF
O Award of cer t i f i cat es t o MS Chemi cal Technol ogy
st udent s of BITS, Pilani
O Declarat ion of st udent ships t o children of st aff who
secured admission in Indian Inst it ut e of Technology
(IIT)
O Present at ion of cash awards t o children of st aff who
scored more t han 90% marks i n each of t he t hree
science subj ect s in t he XII st andard examinat ion. On
t his occasion, t he IICT Diamond Jubilee Sport s Award
Fu n ct i o n w as al so h el d. Sh r i Ar sh ad Ayu b, ex-
member of Indi an cri cket t eam was t he Guest of
Honour. Dr. K. V. Raghavan, t he t hen Direct or of IICT,
sp oke on t h e occasi on h i g h l i g h t i n g t h e sp or t s
act i vi t i es i n IICT. Awards were p r esent ed t o IICT
sport smen by t he chief guest .
* K.T. Achaya Memorial Lecture - October 1, K.T. Achaya Memorial Lecture - October 1, K.T. Achaya Memorial Lecture - October 1, K.T. Achaya Memorial Lecture - October 1, K.T. Achaya Memorial Lecture - October 1,
2003 2003 2003 2003 2003
The lect ure was t he first Diamond Jubilee event under
t he leadership of Dr. J. S. Yadav who t ook over as Direct or
on 1st Oct ober, 2003. The Indian Inst it ut e of Chemical
Technology and Oil Technologist s Associat ion of India,
Sout hern zone decided t o organize a memorial lect ure
ever y year on Dr. Achayas birt hday, as a fit t ing t ribut e
t o his out st anding cont ribut ions t o t he growt h of Indian
oils & fat s R & D. The K.T. Achaya Memorial lect ure was
del i vered by Dr.P. M.Bhargava, a cl ose associ at e of Dr.
K.T. Achaya on Oct ober 6, 2003 in t he IICT Audit orium.
Dr. J. S. Yadav welcomed t he par t icipant s and int roduced
t he speaker t o t he audi ence. Dr. Vi j ay Kal e, Presi dent
OTAI (SZ) i nf or med about t he genesi s of K. T. Achaya
Endowment Fund inst it ut ed by t he OTAI and how t he
finances would be raised. The shor t biodat a of Dr.K. T.
Achaya was read out t o t he august audience which is
given below:
Dr. Konganda Thammu Achaya was born on Oct ober 6,
1923 at village Kolligil in t he st at e of Tamil Nadu. Aft er
complet ing his educat ional pursuit s in 1950, he j oined
t he laborat ory and was associat ed wit h t he Inst it ut e t ill
1971. As deput y Di rect or and Head of Oi l s and Fat s
Di vi si on, he bui l t t he school of Li pi d Chemi st ry and
Technology. Dr. Achaya, a doyen in t he field of Oils and
Fat s, w as h o n o u r ed w i t h sever al n at i o n al an d
i nt ernat i onal awards. Dr. Achaya breat hed hi s l ast on
Sept emb er 5, 2002. Dr.K.V.Raghavan, Di rect or Grade
Sci ent i st , spoke about hi s associ at i on wi t h Dr. Achaya
and t he achievement s of Dr. Achaya. Dr. P. M. Bhargava
paid t ribut es t o Dr.Achaya and t hen delivered t he First
K. T. Achaya Memor i al Lect ure on The Rel at i onshi p
b et w een Sci en ce an d Ar t s. Dr.Bh ar g ava i n h i s
present at ion lucidly explained t he int ricat e relat ionship
and symmet ry bet ween art and sci ence. He kept t he
au d i en ce sp el l b o u n d w i t h h i s p r esen t at i o n . The
meet ing ended wit h a vot e of t hanks by Dr. B.V.S.K.Rao,
Honorar y Secr et ar y, OTAI (SZ). On t hi s occasi on, t he
renovat ed second f l oor of t he mai n bui l di ng of IICT,
named as K. T. Achar ya Wi ng, was decl ared open by
Padmabhushan Dr. P.M.Bhargava, Founder Di rect or of
CCMB.
Dr. P.M. Bhargava is garlanding the photo of Dr. Achaya
13
* IICT Founder IICT Founder IICT Founder IICT Founder IICT Founders Day Lecture- November 7, s Day Lecture- November 7, s Day Lecture- November 7, s Day Lecture- November 7, s Day Lecture- November 7,
2003 2003 2003 2003 2003
The lect ure was on t he t opic New Dimensions t o NMR
Applicat ions: Disease Diagnosis, Treat ment , Monit oring
and Direct Social Relevance was delivered on Friday, 7
t h
Novemb er 2003 b y Dr. C. L. Kh et r ap al , FNA &
Dist inguished Professor, Cent re for Biomedical Magnet ic
Resonance, Sanj ay Gand hi P.G.Inst i t ut e of Med i cal
Sciences, Lucknow. Dr. J. S. Yadav, Direct or, IICT presided
over t he funct ion.
* UNESCO Regional Training Workshop on UNESCO Regional Training Workshop on UNESCO Regional Training Workshop on UNESCO Regional Training Workshop on UNESCO Regional Training Workshop on
Environmental Chemistry Environmental Chemistry Environmental Chemistry Environmental Chemistry Environmental Chemistry- November 10 - - November 10 - - November 10 - - November 10 - - November 10 -
November 15, 2003 November 15, 2003 November 15, 2003 November 15, 2003 November 15, 2003
Th e w o r ksh o p w as h el d f r o m No vemb er 10 t o
November 15, 2003. This resident ial Workshop - cum -
Tr ai n i n g Cour se on Envi r on men t al Ch emi st r y w as
sponsored by UNESCO Regi onal Cent re, Del hi f or t he
t eaching facult y from India and neighbouring count ries
l i ke Sri Lanka, Bangl adesh and Nepal . 18 Part i ci pant s
from all over India and 4 from Sri Lanka, one each from
Bangladesh and Nepal at t ended t he Workshop. It was
i naugurat ed by Dr. A. C. Kunwar, Incharge Di rect or of
IICT and Dr. K. V. Raghavan, Direct or Grade Scient ist of
IICT d el i ver ed t h e In au g u r al Lect u r e o n Gr een
Technol o g i es. Exp er t s f r om IICT, Jawahar l al Nehr u
Tech n o l o g i cal Un i ver si t y (JNTU), En vi r o n men t al
Pr ot ect i o n Tr ai n i n g Resear ch In st i t u t e (EPTRI),
Pat ancheruvu Environment al Tech. Lt d (PETL) and M/ s
Sarvot ham Chemicals delivered 16 lect ures on different
t opics viz., air, wat er and soil pollut ion, ecology, safet y,
hazard t reat ment & ri sk assessment t echnol ogi es by
physi cal , chemi cal and bi ol ogi cal met hods, sampl i ng
t echniques, phyt oremediat ion et c. The par t icipant s were
t aken t o environment al facilit ies of JNTU, PETL & EPTRI
f or exp osi ng t hem t o l at est st at e of ar t f aci l i t i es i n
envi ronment al chemi st r y. At t he Val edi ct or y Funct i on
on 15t h November, 2003, Dr.J.S. Yadav, Di rect or, IICT
present ed cer t ificat es t o t he par t icipant s. Dr. M. S. Alam,
Seni or Programme Speci al i st - Sci ence, UNESCO, New
Delhi, was t he Chief Guest . The Course Coordinat or, Dr.
M. Vai r aman i , Dep u t y Di r ect o r & Head , An al yt i cal
Chemist ry Division, summarized t he proceedings of
t he course.
* National Seminar National Seminar National Seminar National Seminar National Seminar Fuel To Fuel Cells Fuel To Fuel Cells Fuel To Fuel Cells Fuel To Fuel Cells Fuel To Fuel Cells - -- --
December 4-5, 2003 December 4-5, 2003 December 4-5, 2003 December 4-5, 2003 December 4-5, 2003
The seminar which was held on Dec. 4-5, 2003 was co-
sponsored by t he Minist ry of Non-convent ional Energy
Sources. Dr. K B S Prasad, Head, Coal , Gas & Energy
Division, IICT, Hyderabad int roduced about t he seminar
an d i t s i mp o r t an ce. In t h e p r esen t scen ar i o w i t h
increased awareness on t he levels of carbon emissions,
t he fuel cel l t echnol ogy has assumed great rel evance
g l o b al l y as su b st i t u t e t o co n ven t i o n al p o w er
generat ion for all applicat ions. The fuel processor must
be small, have high reforming efficiency, give hydrogen
of high purit y and must not be expensive. To achieve
t his, it must feat ure ext ensive int egrat ion bet ween heat
and mass t r ansf er, chemi cal react i ons and i mpur i t y
removal. It is a t ask which present s t he designers and
manuf act ur er s unusual chal l enges, t hat i s evad i ng
solut ion. The overall challenge, t herefore, is t o achieve
a fully int egrat ed fuel processing syst em, which accept s
a wi de range of f uel s at normal l evel s of puri t y and
p r o d u ces a h yd r o g en r i ch g as mi xt u r e o f q u al i t y
t ol erat ed by t he f uel cel l el ect rodes at an af f ordabl e
cost so t hat fuel cell power becomes widespread and
common. The i ssues connect ed wi t h R&D sup por t ,
Gover nment s r ol e, cod es & st and ar ds, commer ci al
financing, infrast ruct ure and t ime scale of development
were ident ified as crit ical for t he development of t his
t echnol ogy. The semi nar was i naugur at ed b y Pr of.
M.S.Anant h, Di rect or, Indi an Inst i t ut e of Technol ogy,
Delhi. Dr. R K Bhat t acharya, General Manager, Corporat e
R&D, BHEL, Hyderabad gave t he Keynot e Address. The
t w o -d ay semi n ar w as d i vi d ed i n t o f i ve Tech n i cal
Sessi ons, a Panel Di scussi on, an IICT Sessi on and a
Concluding Session. Dr. J S Yadav, Direct or, IICT presided
over t h e In aug ur al Fun ct i on . Amon g t h e emi n en t
speakers of t he seminar were: Prof. B Viswanat han, Head,
Depart ment of Chemist r y, IIT, Madras, Prof. Basu, IIT, Delhi,
Dr. Devot t a, Direct or, NEERI, Nagpur, Dr. K V Raghavan,
former Direct or, IICT, Hyderabad, Dr. H S Mait i, Dierct or,
CGCRI, Ko l k at a, Dr. V V Kr i sh n an , Un i ver si t y o f
14
Pennsylvania, USA, Dr. V M Desai, E I DuPont India Lt d.,
Gurgaon, Dr. K S Dhat hat hreyan, formerly, SPIC Science
Foundat ion, Madras, Mr. Sidhar t ha Sen, GAIL, New Delhi
an d Mr R K Kashyap , GAIL, New Del h i . Dr.M
Subrahmanyam, Sci ent i st , Cat al ysi s, IICT proposed a
vot e of t hanks.
* Nayudamma M emor i al Cr i cket Tour nament
December 12- December 14, 2003
It was organi zed from December 12 t o December 14,
2003. Th e f o l l o w i n g t eams p ar t i ci p at ed i n t h e
t ournament :
O Depart ment of Informat ion Technology
O Nuclear Fuel Complex, Hyderabad
O Depar t ment of Sci ence and Technol ogy, New
Delhi
O Depart ment of Environment and Forest s, New
Delhi
O All India CSIR Labs
O Indian Met eorological Depart ment , New Delhi
O El ect r oni cs Cor p or at i on Ind ust r i es Li mi t ed ,
Hyderabad
O CSIR Laborat ories of Hyderabad
Anand, Vice-Presi dent , Hyderabad Cri cket Associ at i on
and Assist ant Commissioner of Police, Hyderabad. The
cricket mat ches were held for four days on knockout
b asi s i n t he IICT cr i cket gr ound. The wi nner of t he
t ournament was t he Depart ment of Envi ronment and
Forest s, New Delhi. The closing ceremony was arranged
i n a grand way i n f ront of t he mai n bui l di ng and t he
chief guest was Shri Ranga Reddy, President , Hyderabad
Cri cket Associ at i on. The vot e of t hanks was proposed
by Shri R.K. Sharma, Convener of t he event .
* The First Indian International Conference on The First Indian International Conference on The First Indian International Conference on The First Indian International Conference on The First Indian International Conference on
Artificial Intelligence (IICAI-03) Artificial Intelligence (IICAI-03) Artificial Intelligence (IICAI-03) Artificial Intelligence (IICAI-03) Artificial Intelligence (IICAI-03)-December 18 -December 18 -December 18 -December 18 -December 18
-20, 2003 -20, 2003 -20, 2003 -20, 2003 -20, 2003
The inaugural funct ion was held on 12 December 2003.
It was presided over by Dr. J. S Yadav, Direct or, IICT. Shri R.
K Sharma, COA welcomed t he various cricket t eams t o
IICT. The t our nament w as i naugur at ed b y Shr i C.V.
The conf erence was hel d i n IICT f rom December 18 -
December 20, 2003 and was co-sponsored by IICT, IEEE
Syst ems, Man an d Cyb er n et i cs So ci et y (USA);
Int ernat i onal Federat i on f or Inf ormat i on Processi ng
(Aust r al i a); IOS Pr ess ( The Net her l and s) and Wor l d
Federat i on on Sof t Comput i ng (Japan). Dr. JS Yadav,
Di r ect o r, IICT i n au g u r at ed t h e co n f er en ce an d
highlight ed t he import ance of art ificial int elligence and
i t s appl i cat i ons i n vari ous f i el ds. Dr. USN Mur t y, Head,
Biology Division spoke on t he genesis of t he conference
and t he possible applicat ions of art ificial int elligence in
cont rolling t he vect or borne diseases. 126 Papers were
p r esen t ed i n 18 sessi o n s d u r i n g t h e t h r ee- d ay
conf erence. Bi ocomput i ng and Bi oi nf ormat i cs sessi on
at t r act ed t h e at t en t i o n o f many sci en t i st s. The
conf erence was successf ul l y concl uded on December
20, 2003.
Shri C.V. Anand (Right) is inaugurating the Nayudamma
Cricket Tournament
Inauguration of the IICAI-03 by Dr. J.S. Yadav, Director
15
* Dr. P. S. Murti Memorial Lecture and IICT Dr. P. S. Murti Memorial Lecture and IICT Dr. P. S. Murti Memorial Lecture and IICT Dr. P. S. Murti Memorial Lecture and IICT Dr. P. S. Murti Memorial Lecture and IICT
Diamond Jubilee Seminar on Chemical Diamond Jubilee Seminar on Chemical Diamond Jubilee Seminar on Chemical Diamond Jubilee Seminar on Chemical Diamond Jubilee Seminar on Chemical
Engineering - January 10, 2004 Engineering - January 10, 2004 Engineering - January 10, 2004 Engineering - January 10, 2004 Engineering - January 10, 2004
The Chemi cal Engi neer i ng Di vi si on of t he Inst i t ut e
o r g an i zed a o n e-d ay Nat i o n al Semi n ar Ch emi cal
Engi neeri ngGl obal Chal l enges on January 10, 2004.
The basi c obj ect i ve of t hi s semi nar was t o provi de a
forum for t he chemical engineers working in indust r y,
nat i onal l ab or at or i es and acad emi c i nst i t ut i ons t o
exchange ideas and discuss problems of mut ual int erest
t o advance R&D in front ier area of chemical engineering.
The focus of t he semi nar was on t he front i er areas of
Ap p l i ed Th er mo d yn ami cs, React i o n En g i n eer i n g,
Model i ng and Si mul at i on, Fl ow of Granul ar Mat eri al s
an d Pr o cess Saf et y. Th e semi n ar t h eme i n cl u d ed
t echni cal sessi ons wi t h i nvi t ed l ect ur es b y var i ous
expert s t he field of Chemical Engineering. These lect ures
include, t he 8
t h
P.S. Murt i Memorial Lect ure delivered by
Dr. D.S. Vi sw an at h , an Emer i t u s Pr o f esso r at t h e
Uni ver si t y of Mi ssour i , Col umb i a, USA, f ol l owed b y
special lect ures by eminent chemical engineers like Dr.
K.V. Raghavan, former Direct or of IICT, Dr. B.D. Kulkarni,
Di r ect or Gr ade Sci ent i st and Head of t he Chemi cal
En g i n eer i n g Di vi si o n at t h e Nat i o n al Ch emi cal
Laborat or y, Pune, Professor D.V. Khakhar of t he Indi an
Inst it ut e of Technology, Mumbai, and Sri. V.V. Bhuj le of
Ci ba-Gei gy Pvt . Lt d, Mumbai . The semi nar had al so a
Panel Di scussi on. About 200 del egat es f rom i ndust r y,
acad emy an d R&D i n st i t ut i on s p ar t i ci p at ed i n t h e
seminar.
* National Workshop on National Workshop on National Workshop on National Workshop on National Workshop on Industrial Applications Industrial Applications Industrial Applications Industrial Applications Industrial Applications
of Chemoinformatics and Computer Aided of Chemoinformatics and Computer Aided of Chemoinformatics and Computer Aided of Chemoinformatics and Computer Aided of Chemoinformatics and Computer Aided
Drug Design Drug Design Drug Design Drug Design Drug Design - January 12 to January 17, - January 12 to January 17, - January 12 to January 17, - January 12 to January 17, - January 12 to January 17,
2004 2004 2004 2004 2004
Molecular Modeling Group, Organic-I division organized
a six-day nat ional workshop on Indust rial applicat ions
of chemoinformat ics and comput er aided drug design
from January 12 t o January 17, 2004. It had about 13
part icipant s from Indust ry, 13 from academic inst it ut es
and 4 from nat ional laborat ories. The par t icipant s were
f rom various backgrounds, such as chemist ry, biology,
comput er science, chemical engineering and medicine.
Among t he f acul t y, t here were 5 each f rom Indust r y
and Uni versi t i es and 8 f rom nat i onal l aborat ori es. Al l
t he si x-d ays, t he p ar t i ci p ant s wer e exp osed t o t he
mol ecul ar model i ng and i t s pract i cal and t heoret i cal
asp ect s. It w as an i n t en si ve, b r ai n st or mi n g an d a
t hought -provoking workshop dealing wit h most of t he
mu l t i f acet ed asp ect s o f ch emo i n f o r mat i cs an d
comput er-aided drug design. An import ant feat ure of
t he workshop was t hat it occupied almost 50% of t he
t ime schedule on hands-on sessions. In addit ion t o t he
brochure of all t he invit ed lect ures, fort y (40) int erest ing
papers running int o 400 pages were phot ocopied and
g i ven t o al l t h e p ar t i ci p an t s. Most of t h e p ub l i cl y
avai l ab l e sof t war e p ackages wer e p ut i n a CD and
di st ri but ed among t he part i ci pant s.
* National Science Day Celebrations - February National Science Day Celebrations - February National Science Day Celebrations - February National Science Day Celebrations - February National Science Day Celebrations - February
28, 2004 28, 2004 28, 2004 28, 2004 28, 2004
The cel ebrat i ons were hel d on February 28, 2004 i n
co l l ab o r at i o n w i t h A.P. Co u n ci l o f Sci en ce an d
Tech n o l o g y, Hyd er ab ad . Nat i o n al Sci en ce Day i s
celebrat ed every year on February 28 t o commemorat e
t he announcement of t he di scovery of Raman ef f ect
by Sir C.V. Raman. Dr. P. Rama Rao, Adviser, S&T and Higher
Educat i on was t he chi ef guest at t he f unct i on whi ch
was presided over by Prof. C Subba Rao, chairman, AP
St at e Counci l f or Hi gher Educat i on. Prof . J. M. Nai du
spoke about t he i mport ance of t he Nat i onal Sci ence
Day followed by t he address of Dr. A. C. Kunwar, Incharge
Di r ect or, IICT. On t hi s occasi on, t he Andhra Pradesh
Sci ent i st Award was present ed t o Dr. B.M. Choudar y,
National Science Day Celebrations - 2004
16
Represent at i ve, ISO 9001:2000 Qual i t y Management
Syst em w el co med t h e p ar t i ci p an t s. Dr. J. S.Yad av,
Di r ect or, IICT, i n hi s op eni ng r emar ks, g ave a b r i ef
descript ion of various research and analyt ical act ivit ies
at IICT. Dr. A. C. Kunwar, Direct or grade Scient ist , made a
det ailed present at ion on t he analyt ical facilit ies at IICT.
Sri A. Kri shna Reddy, Sci ent i st -In-Charge, Pi l ot Pl ant s
mad e a b r i ef p r esen t at i on on p i l ot p l an t f aci l i t i es
avai l ab l e at IICT. Twen t y t wo r ep r esent at i ves f r om
various indust ries part icipat ed in t he meet ing. They had
direct int eract ion wit h t he Direct or, Dr.A.C.Kunwar, Dr .
Shakunt hal a Madhavendra, Dr. Md. Ki f ayat ul l ah and
Sci ent i st si n-Charge of vari ous anal yt i cal cent res. The
meet i ng was qui t e usef ul i n get t i ng i nf ormat i on f or
improving t he scope and qualit y of analyt ical services.
* Seminar on Virtual Reality in Pursuit of Seminar on Virtual Reality in Pursuit of Seminar on Virtual Reality in Pursuit of Seminar on Virtual Reality in Pursuit of Seminar on Virtual Reality in Pursuit of
Excellence - June 4-5, 2004 Excellence - June 4-5, 2004 Excellence - June 4-5, 2004 Excellence - June 4-5, 2004 Excellence - June 4-5, 2004
Devel o p men t s w er e mad e i n Vi r t u al Real i t y ( VR)
t echnology ranging from walk t hroughs in plant layout
t o aircraf t simulat ions and 3D gaming. Virt ual realit y is
an emerging t echnology, which has wide pot ent ial wit h
applicat ions in almost all t he scient ific fields. However,
t he devel opment s were most l y conf i ned t o research
an d g ami n g r at h er t h an an y r eg u l ar i n d u st r i al
applicat ions. This seminar aimed t o bring exper t s and
users from R&D Inst it ut es, Academic Inst it ut es, Defence,
Indust ry and Government as well as Non-Government al
agencies t o discuss various possibilit ies of bringing t his
t echnol ogy t o t he common man. The semi nar was
inaugurat ed by Dr R N Singh, Direct or s Grade Scient ist ,
NGRI, Hyderabad. The seminar consist ed of five t echnical
scient ist , IICT by t he special invit ee Dr. A. V. Rama Rao,
Chai rman & Managi ng Di rect or, AVRA Laborat ori es i n
recogni t i on of hi s si gni f i cant cont ri but i ons t o sci ence
and t echnology. Vot e of t hanks was proposed by Mrs. C.
B. Lakshmi, Head, Research Management .
Dr. Manju Sharma is garlanding the photo of Dr. S.S. Bhatnagar
* 12th S.S.Bhatnagar Memorial Lecture - April 12th S.S.Bhatnagar Memorial Lecture - April 12th S.S.Bhatnagar Memorial Lecture - April 12th S.S.Bhatnagar Memorial Lecture - April 12th S.S.Bhatnagar Memorial Lecture - April
1, 2004 1, 2004 1, 2004 1, 2004 1, 2004
On April1, 2004 t he 12t h S.S.Bhat nagar Memorial Lect ure
was del i vered by Dr. (Mrs) Manj u Sharma, Advi ser t o
Mi ni st er for Sci ence and Technol ogy, Government of
India. Dr. Sharma gave a scint illat ing lect ure on t he t opic
Towards a Sust ai nabl e Bi of ut ure-A Synergy bet ween
In t er d i sci p l i n ar y Resear ch , En t r ep r en eu r sh i p an d
Commerci al i sat i on i n Bi ot echnol ogy
* National Technology Day - May 11, 2004 National Technology Day - May 11, 2004 National Technology Day - May 11, 2004 National Technology Day - May 11, 2004 National Technology Day - May 11, 2004
India conduct ed five nuclear t est s on May 11, 1998 and
j oi ned t he Nucl ear Cl ub. Thi s d ay i s cel eb r at ed as
Nat i onal Technol ogy Day and IICT t oo cel ebrat es t he
day every year.
a) a) a) a) a) National Technology Day lecture- 2004 National Technology Day lecture- 2004 National Technology Day lecture- 2004 National Technology Day lecture- 2004 National Technology Day lecture- 2004
On t h i s o cassi o n , Pad mash r ee Dr. A. V. RamaRao
delivered t he Nat ional Technology Daylect ure-2004. The
t opi c of t he l ect ure was Process Chemi st r y - Can an
academic lend fresh perspect ive t o t he subj ect ?
b) b) b) b) b) Interactive Meeting with ISO Clients Interactive Meeting with ISO Clients Interactive Meeting with ISO Clients Interactive Meeting with ISO Clients Interactive Meeting with ISO Clients
An i nt eract i ve meet i ng wi t h ISO cl i ent s was hel d on
May 11, 2004 as par t of Technology Day Celebrat ions.
Dr. Sh ak u n t h al a Mad h aven d r a, Man ag emen t
Dr. A.V. Rama Rao, CMD, AVRA Labs is welcomed by
Dr. J.S. Yadav, Director, IICT
17
sessi ons spread over one and a hal f days. About 98
members part icipat ed in t he seminar. The first t echnical
sessi on deal i ng wi t h concept s real i t y, st ar t ed wi t h an
invi t ed speech on Vi r t ual real i t y an advanced t ool of
vi sual i zat i on and di gi t al prot ot ype del i vered by an
exp o n en t i n vi r t u al r eal i t y t ech n o l o g i es, Sh r i K
Rag h ur am, Sen i or Dep ut y Gen er al Man ag er, BHEL
Cor porat e R&D, Hyderabad. Dr CRJ Prakash Nai du, a
st alwart from Defence Organizat ion Cent re for Art ificial
Int el l i g ence and Rob ot i cs, Bang al or e d el i ver ed an
invit ed speech on Current applicat ion of Virt ual Realit y
and Technologies Trends. Dr.K Ramanat han, Scient ist G,
ADA, Bangal ore spoke on Vi r t ual Real i t y Prot ot ypi ng
Technologies in t he development of LCA. The discussion
st ar t ed wi t h t he d evel op ment of f l i ght si mul at or s,
int erest of NASA in t he development of flight simulat ors
and molecular modeling. Maj or aspect s of Vir t ual Realit y
such as Soft ware, Dat abase, Obj ect s, Geomet ry Creat ion,
Obj ect s i n VR Envi r onment & VR Envi r onment were
O Efficient usage of MSDS using VR
O Vi r t u al Li b r ar y i s an In f o r mat i o n t o o l f o r
sci ent i st s
O VR Training for inspect ion st aff of TAC/ Fire
O Fight ing personnel for hazardous occupancies
O Vir t ual Welding, Myt h or Realit y
O Vi r t ual Environment Training
O Agi t at i on Syst ems
* 14th Sidhu Science Lecture - July 2, 2004 14th Sidhu Science Lecture - July 2, 2004 14th Sidhu Science Lecture - July 2, 2004 14th Sidhu Science Lecture - July 2, 2004 14th Sidhu Science Lecture - July 2, 2004
It was delivered by Professor S. K. Bramhachari , Direct or,
Inst it ut e of Genomics and Int egrat ive Biology, New Delhi
on SNPs, Chips, Informat ics and Predict ive Medicine, on
Friday, t he July 2, 2004 at S. B. Hall, Nat ional Geophysical
Research Inst it ut e, Uppal Road, Hyderabad.
Dr. G. S.Sidhu Foundat ion Trust was founded in t he year
1981 by some of his close associat es. One of t he act ivit ies
of t he Trust is t o organize lect ures by eminent scient ist s
on t op i cs of sci ent i f i c i nt er est t o coi nci de wi t h hi s
b i r t hday. Thi r t een such l ect ur es have al ready b een
organi sed t i l l dat e host ed by t he Indi an Inst i t ut e of
Chemical Technology.
* IICT Diamond Jubilee Valedictory Function - IICT Diamond Jubilee Valedictory Function - IICT Diamond Jubilee Valedictory Function - IICT Diamond Jubilee Valedictory Function - IICT Diamond Jubilee Valedictory Function -
August 4, 2004 August 4, 2004 August 4, 2004 August 4, 2004 August 4, 2004
Indi an Inst i t ut e of Chemi cal Technol ogy, Hyderabad
organised it s Diamond Jubilee Valedict or y Funct ion on
discussed. The invit ed lect ures were of Dr Manj unat h, a
sci ent i st of NRSA, Hyd er ab ad, on Fl y 3D Ter r ai n
Visualizat ion Soft ware; Prof.C Kameswar Rao of Deccan
College of Engineering, on Pat ent ing Trends in Virt ual
Prot ot ypi ng. Prof. P J Narayanan f rom IIIT, Hyderabad
discussed in det ail t he Modeling languages. Besides t he
above i nvi t ed l ect ures, 21 papers were present ed on
t he appl i cat i ons of Vi r t ual Real i t y. IICT present ed t he
following on applicat ions of Vir t ual Realit y in Chemical
Indust ry :
Prof. Bramhachari is delivering the lecture
Dr.J.S.Yadav, Director, IICT is welcoming the chief guest during
the Seminer on Virtul Reality in Pursuit of Excellence
18
August 4,2004. Shri Kapil Sibal, Honble Minist er of St at e
(Independent charge), S&T and Ocean Devel opment ,
Govt . of Indi a and Vi ce-Presi dent , CSIR was t he chi ef
guest . Shri Si bal , i n hi s Di amond Jubi l ee address, sai d
t hat Counci l of Sci ent i f i c & Indust ri al Research (CSIR)
sh oul d f or g e t ech n ol og i cal r evol ut i on i n t h e 21st
cent ur y. Int er-disciplinary co-operat ion and part nerships
i n t he sci ent i f i c communi t y were most i mport ant t o
real i ze t he pot ent i al of t echnol ogi cal i nnovat i ons and
f aci l i t at e t hei r t ransf er f rom t he l aborat ori es t o t he
mar ket i n t h e co mi n g d ays. Sh r i Si b al asked t h e
sci ent i st s t o f ocus on t echnol ogy t hat woul d ensure
food, shelt er, healt hcare and educat ion t o t he 700 million
people of t he count ry whose mont hly earnings are less
t han $2 a day (Rs.3000/ - per mont h). He explained t hat
if we did not t ouch t he lives of t hese people, t echnology
will be of no use. While land product ively was decreasing,
populat ion was on t he rise. He reminded t he scient ific
communit y t o solve some of t hese complex problems
of t he people. The Minist er assured t he scient ist s t hat
aut onomy of sci ent i f i c i nst i t ut i ons l i ke IICT woul d be
prot ect ed.
Dr. R.A.Mash el k ar, Di r ect or Gen er al , CSIR sai d t h at
count ry had done well in t he science and t echnology
and IICT had creat ed a ni che f or i t sel f i n t he f i el d of
chemist ry and chemical t echnology, being a Diamond
Shri Kapil Sibal is addressing the gathering during D.J. function
in t he CSIR chain. He st ressed t he need for coming wit h
newer product s in t he wake of t he pat ent regime t o be
i nt roduced f rom 2005. He sai d t hat t he l aborat ori es
shoul d ad op t t o t he emer gi ng amb i ence and new
reforms should t ake t he count ry in t he pat h of progress.
Earl i er, Dr. J.S.Yadav, Di rect or, IICT wel comed t he huge
g at h er i n g comp r i si n g of sci en t i st s, t ech n ol og i st s,
members f rom academi a and i ndust ry and IICT st af f
members and expl ai ned i n det ai l t he growt h of t he
laborat ory in t he past sixt y years, right from it s incept ion
on 5t h August 1944 t hrough t he Fi rman of Ni zam of
Hyd er ab ad t o i t s r en ami n g as In d i an In st i t u t e o f
Chemical Technology in 1989 and it s Golden Jubilee in
1994. On t hi s occasi on, Shri Kapi l Si bal rel eased t he
Di amon d Jub i l ee Souven i r an d p r esen t ed Rol e of
Honour t o ret i r ed and wor ki ng sci ent i st s of IICT. A
number of f ormer Di rect ors and IICT cl i ent s recal l ed
t heir associat ion and t he works done at t he laborat ory
earlier. Dr.A.C.Kunwar,Direct or Grade Scient ist proposed
a vot e of t hanks.
The Honbl e Mi ni st er i naugurat ed t he IICT Di amond
Ju b i l ee mo n u men t an d p l an t ed a sap l i n g o n t h i s
occasi on. He al so i naugurat ed t he Bi ot echnol ogy and
Bi oprocessi ng Cent re and OPCW t est l ab i n t he Mass
Spect romet ry Cent re. He vi si t ed t he newl y devel oped
Nanomat erials Science Laborat ory, Animal Quarant ine
Facilit ies and Nat ural Product s Chemist r y Laborat ory.
Honble Minister Shri Kapil Sibal is releasing the Souvenir
19
20
21
CSIR concei v ed and i d ent i f i ed ar ound 56 Net wor k
Programmes / Proj ect s for implement at ion during 10
t h
Fi ve Year Pl an (2005-07) by net wor ki ng among CSIR
l aborat ori es. Based on t he expert i se and compet ence
available wit h CSIR Laborat ories and specific role t o be
performed by di fferent CSIR Labs, DG has const i t ut ed
Task Force Net work Proj ect / Programme on Developing
Green Technologies for Organic Chemicals (CMM-0006)
and Gl obal l y Compet i t i ve Chemi cal s, Processes (COR-
0003) wit h Direct or, IICT as Chairman and IICT as Nodal
Lab or at o r y. Th e o t h er memb er s / p ar t i ci p at i n g
laborat ories wit h regard t o CMM-0006 are Direct ors or
t heir nominees of CECRI, CFRI, CIMAP, IIP, NCL, NEERI, RRL
(Jorhat ), RRL ( Tri .), RRL (Jam), RRL (Bhu), CSMCRI, IHBT
along wit h represent at ives and a senior scient ist of CSIR
Hq r s. The ot her memb er s / p ar t i ci p at i ng l ab s wi t h
regard t o COR-0003 are Direct ors or t heir nominees of
CFRI, CIMAP, IIP, NCL, NEERI, RRL (Tri), RRL (Jam), RRL (Bhu),
CSMCRI, IHBT al ong wi t h represent at i ve and a seni or
scient ist of CSIR Hqrs.
Par t i ci p at i n g l ab o r at o r i es i d en t i f i ed 26 p r o j ect
component s under Development of Green Technologies
f or Organi c Chemi cal s coveri ng areas l i ke (a) Green
processes for medicinal plant s (b) Value added product s
from bio-mass and agro indust rial wast es (c) Alkylat ion
an d o xi d at i o n o f ar o mat i c co mp o u n d s (d )
Fl u o r o o r g an i cs an d (e) No vel meso p h o r o u s n an o
mat eri al s and 16 proj ect component s were i dent i f i ed
under Gl obal l y Compet i t i ve Chemi cal s and Processes
covering t he areas like (a) Funct ional and nat ural dyes
ef f i ci ency processes f or bi o-act i ves (b) Novel Ti -Ti O
2
processes and (c) Alt ernat ive fuels/ fine chemicals.
Vari ous proj ect component s al ong wi t h par t i ci pat i ng
laborat ories are given in Fig. 1 and Fig. 2.
i) Devel o p i n g Gr een Tech n o l o g i es f o r Or g an i c
Chemicals (CMM-0006)
ii) Gl obal l y Compet i t i ve Chemi cal s, Processes and
Product s (COR - 0003)
Out put of t he f ol l owi ng net worki ng proj ect s duri ng
2003-05 are given in t able 1 & 2. IICT out put s are also
given in respect ive R&D sect ions and ot her part icipat ing
laborat ories may be report ing in t heir annual report s.
CSIR NETWORK PROJECTS CSIR NETWORK PROJECTS CSIR NETWORK PROJECTS CSIR NETWORK PROJECTS CSIR NETWORK PROJECTS
Dr. A.V. Rama Rao, CMD, AVRA Labs and former Director,
IICT & Dr. J.S. Yadav, Director IICT (right) are seen during the
Network Projects Meeting.
Meeting in Progress
22

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30
* APPLIED RESEARCH :
*Extraction and Isolation of Novel Synergistic
Anti-cancer Chemical Composition from Cedar
wood(US patent No. 6649650* ).
Cedar wood(Cedrus deodara), a commercial source for
cedar wood oi l i s di scovered as a source of a novel
synergist ic lignan mixt ure of non volat ile compounds
f or ant i cancer act i vi t y. The nonvol at i l e f r act i on i s
essent ially found t o be a mixt ure of t hree lignans, (-)-
mat airesinol, (-)-nort rachelogenin and a dibenzylbut y-
rol act ol l i gnan. These t hr ee comp ounds const i t ut e
about 3-4% of t he dri ed wood. Furt her when t hese
t hree compounds when t est ed over various cancer cell
lines, individually t hey are act ive only on one or t wo cell
l i nes. As mi xt ure t hey are f ound t o be act i ve over a
wide range of cell lines and also more effect ive on each
of t he cel l l i nes. Based on t hi s observat i on a process
has been developed t o isolat e t he lignan mixt ure where
t he mi xt ure of t he t hree l i gnans cont ri but e t o >96%
and present in a rat io of approximat ely 10:80:10. The
impurit y profiling shows t hat t hese t hree compounds
are responsible for t he biological act ivit y. It is also found
t hat t hese t hree compounds are present in t his rat io in
t his plant . A process is developed for t he ext ract ion of
t his lignan mixt ure from t he plant which is commercially
viable and involves no chromat ography. The LD50 value
is found t o be >2200mg/ Kg wit h signs of init ial sedat ion.
It is licensed t o M/ S Indigene Pharmaceut icals Lt d., USA
and furt her development al work is in progress.
* New Nat ural Agent f or Treat ment of
Gastrointestinal Toxicit y, Associated Symptoms
and Ulcers
The plant s creat e unexpect ed and novel st ruct ures t o
prot ect t hemsel ves f rom predat or organi sm. By t ri al
an d er r o r, sever al p l an t s an d p l an t p r o d u ct s ar e
ident ified as drugs. Nat ural Product drugs alt hough are
h i g h l y ef f ect i ve an d f r ee f r om si d e ef f ect s h ave a
di sadvant age wi t h respect t o short suppl y and of t en
have a complicat ed st ruct ure making t heir manufact ure
d i f f i cul t or somet i mes i mp ossi b l e. Nat ur al p r od uct
drugs have been a source of l ead st ruct ure i n drug
design and development . Semi synt het ic analogues or
synt het i c anal og ues cl osel y r el at ed t o t he nat ur al
product drug of lead are synt hesized and screened t o
improve t heir act ion. In t he light of above descript ions,
i sol at i on work at IICT af f orded f l avonoi d deri vat i ves
which are pot ent ant iulcer agent s increasing t he gast ric
pH, mucosal l i ni ng of st omach and rel at ed di sorders
leading t o t he ident ificat ion of plant s belonging t o t he
genus Oroxyl um, which cont ained in subst ant ial yields
pot ent ant i ul cer f l avonoi ds. Pl ant s bel ongi ng t o t he
genus Oroxyl um have been advocat ed i n t radi t i onal
medical pract ice of India for several diseases. In folklore
medicine in India, t he powdered st em bark is used t o
t reat dysent er y, diarrhoea, sore t hroat , cough and bone
f ract ures (Kausi k, P and Dhaman A. K, The medi ci nal
plant s and crude drugs of India, 2000, 398). A new pot ent
broad spect rum ant iulcer agent has been isolat ed which
d i sp l ayed r emar kab l e act i vi t y w hen t est ed i n vi vo
agai nst di f f erent model s. US, PCT and Indi an Pat ent s
have been filed.
NATURAL PRODUCTS NATURAL PRODUCTS NATURAL PRODUCTS NATURAL PRODUCTS NATURAL PRODUCTS
Accelerated Solvent Extractor
31
* Single Molecule Ant idiabet ics
In t h e co u r se o f st u d y IICT h as i d en t i f i ed sever al
t r ad i t i onal med i ci nal p l ant s t hat b ear s sub st ant i al
amount s of -g l ucosi d ase i nhi b i t or s coup l ed w i t h
ant i oxi dant act i vi t i es. These act i vi t i es t oget her may
h ave su p er i o r p r even t i ve as w el l as t h er ap eu t i c
i mport ance t han t he exi st i ng modern -gl ucosi dase
i nhi b i t or s. Some of t he wel l st udi ed, p ot ent i al and
published medicinal plant s by IICT are given below:-
1). Veera t aru ( Di chr ost yches ci nerea) i s descr i bed i n
Ayu r ved i c t ext s t o t ackl e d i ab et es b y mu l t i p l e
mech an i sms. IICT h as i so l at ed ver y p o t en t -
glucosidase inhibit or ant ioxidant molecule (-) mesquit ol
in subst ant ial yields from t his medicinal plant based on
in-vit ro st udies and IICT also prepared several analogues
of t hi s mol ecul e. Some of t he mol ecul es have al so
sh o w n an t i h yp er g l ycemi c act i vi t y i n an i mal
experi ment at i on.
(Ref: Bioorganic Medicinal Chemist ry Let t ers, 2003, 13,
2777-2780. USA 6,781,002., USA 0171674 A1, WO 054993
A1, WO 054995 A1)
2). Pippali (Pi per l ongum) also cont ains very high yields
of -glucosidase inhibit ors. Several molecules of various
cl ass have been i sol at ed and i dent i f i ed by IICT as -
glucosidase inhibit ors. IICT work was awarded first prize
in recent IUPAC int ernat ional conference held in New
Delhi ( India ), Jan 26-31,2004. (Ref: USA 2004/ 0081711
AI, WO 041295 AI, MAPA,2004,26,194(Abst ract No 2004-
02-0877)
3) Revan d ch i n i o r Rh u b ar b (Rh eu m em i od i )i s a
prescribed in several t radit ional preparat ion for various
di seases i ncl udi ng di abet es f rom t he rhi zoma of t hi s
medicinal herb. IICT has isolat ed several -glucosidase
i n h i b i t or s cou p l ed w i t h an t i oxi d an t act i vi t i es i n
subst ant ial yields (Ref: Bioorganic Medicinal Chemist ry
Let t ers, 2004, 14, 3841-3845)
4) Similarly, Tuvaraka (Hydnocarpus wi ght i ara) has been
ad vo cat ed i n Ayu r ved i c cl assi cs as ver y p o t en t
med i ci n al p l an t f o r d i ab et es. IICT i so l at ed act i ve
i ngredi ent f rom t hi s medi ci nal pl ant wi t h hi gh yi el ds
and t he -gl ucosi dase ant i oxi dant p ri nci p l e shown
mul t i pl i es act i vi t i es. (Ref : Phyt o t herapy Research
2005,19,277-281).
All t hese molecules offer excit ing opport unit y for t heir
development as ant idiabet ic t herapeut ics.
* Candi dat es f r om CSI R Coor di nat ed
Programme
Duri ng t he l ast si x t o seven years, IICT has devel oped
st at e- o f - t h e ar t an d wo r l d cl ass f aci l i t i es i n New
b i o act i ve mo l ecu l es f r o m n at u r al so u r ces an d
St andardizat ion of Herbal Drugs. The facilit ies include
Per so n al Sep b o x, an au t o mat i c ch r o mat o g r ap h i c
purificat ion syst em and Accelerat ed Solvent Ext ract or.
IICT has al so ent ered i nt o st rat egi c al l i ance wi t h M/ S
Ar ya Vai d ya Sal a, Kot t akal , Ker al a f or new bi oact i ve
mo l ecu l e r esear ch an d p r o cess & p r o d u ct
st an d ar d i zat i o n o f cer t ai n cl assi cal an t i ar t h r i t i c
Ayur vedi c Drugs. The l at er programme i s suppor t ed
by DST under R&D pharmaceut ical Sect ion and will help
t his Ayurvedic Indust ry in modernizat ion and globalize
t hei r p r od uct s. The d evel op ment of new b i oact i ve
mol ecul es f rom nat ural sources i s carri ed out under
t h e u mb r el l a o f CSIR co o r d i n at ed p r o g r amme
Discovery, Development and Commercializat ion of New
Bioact ives & Tradit ional Preparat ions:
Under t his programme IICT is exclusively dealing wit h
Ayurvedic Preparat ions from Arya Vaidya Sala, Kot t t akal.
So far 72 Ayurvedic preparat ions were fract ionat ed and
about 220 fract ions were screened for 20 diseases. Based
on t he In Vi t r o & In Vi vo st udi es of t hese f ract i ons 23
d i sco ver y g r o u p s h ave b een f o r med u n d er Dr u g
Di scovery Programme. Some achi evement s of t hese
discovery groups are described below:
Natural Products
32
Ant igast ric Ulcer:
Originally AP-19 & AP-20 have shown ant igast ric ulcer
act ivit y. Fract ionat ion of t hese t wo preparat ions led t o
loss of act ivit y. Hence several herbal formulat ions have
been designed in collaborat ion wit h AVS. Out of t hese
75k and 76p have shown excel l ent ant i gast ri c ul cer
act i vi t y. 76p i s t aken up f or f ur t h er d evel op men t
because of it s superiorit y over allopat hic drugs such as
o mep r azo l e. CDRI h as co n d u ct ed t h e In vi vo
experi ment s on f i ve model s 1. Col d Rest rai nt i nduced
Ul cer t est (CRU) 2. Aspi ri n Induced Ul cer 3. Hi st ami ne
Induced Ulcer 4. Pyloric ligat ion and 5. Et hanol Induced
Ulcer and IICB has conduct ed H. Pylori i n vi t ro t est . In all
t hese models 76p has shown equal or bet t er act ivit y.
76p is originally designed wit h eleven const it uent s. The
n ecessi t y o f each an d ever y co n st i t u en t i s n o w
est ablished. From t hese st udies effort s are t hen made
t o minimize t he number of const it uent s. 76p Bat ch-18
wit h t he five const it uent s in equal proport ions is found
t o be equally effect ive. The final composit ion of 76p is
t hus est abl i shed. Precl i ni cal t oxi col ogy st udi es are i n
progress.
* Memory Enhancing Act ivit y:
AP- 20 h as o r i g i n al l y sh o w n Memo r y En h an ci n g
propert ies in In vi vo models at CDRI. Fract ionat ion led
t o l oss of act i vi t y. However, based on t he l i t erat ure
report isolat ion of act ive ingredient in t he maj or plant
used in AP-20 is t aken up. A single molecule is ident ified
which has shown Acet ylcholine est erase inhibit ion in In
vi t ro model at CDRI. Racemic form of t his compound
has been synt hesized at IICT and found t o be act ive in
Acet ylcholine est erase model t hough t he inhibit ion is
l ess. Ef f or t s ar e t hen mad e t o op t i mi ze t hi s l ead -
molecule. About 25 analogues were synt hesized. All of
t hem were t est ed bot h i n In vi t ro & In vi vo model s at
CDRI. Four compounds, AP-20am13, AP-20am14, AP-
20am15 and AP-20am16 were i dent i f i ed f or f urt her
devel opment . The f i rst t wo comp ounds have al so
shown posi t i ve resul t s f or ant i depressant act i vi t y at
ITRC i n vi t ro model.
Leishmania:
Two single chemical ent it ies, AP-38PL10 & AP-38PL15
are al so report ed t o be st rongly act ive by IICB. AP-
38PL15 and AP-38PL10 are t est ed in vivo at IICB and
found t o be act ive.
New Bi oact i ve Mol ecul es(nat ural ) di scovered duri ng
2003-05 are as below:
a. Single molecule ant ioxidant s: No.
Free Radical Scavengers(DPPH): 21
Xant hine Oxidase Enzyme Inhibit ors: 10
b. -Glucosidase Inhibit ors: 13
c. Hepat oprot ect i ve agent : 1
d. Ant i cancer compounds: 5
e. Acet ylcholine est erase inhibit ors: 2
f . Ant i bact eri al Compounds: 8
g. Ant i f ungal Compounds: 6
h. Lei shmani a 2
i. Ant i gast ri c ul cer 1
j. Ant i di abet i c 1
& anal ogues 2

Tot al : 72

These mol ecul es are avai l abl e f or rel ease t o i ndust ry
on case t o case basis.
33
* BASIC RESEARCH BASIC RESEARCH BASIC RESEARCH BASIC RESEARCH BASIC RESEARCH
* Designer Molecules from Sugar Amino Acids
and Other Scaffolds:
O Cyclic and acyclic homooligomers of furanoid
sugar amino acids: Cycl i c homool i gomers of
f uranoi d sugar ami no aci ds were synt hesi zed,
e.g, cyclic dimer (left ) and t rimer (right ) of Gaa.
Co n f o r mat i o n al an al ysi s b y NMR an d
const rai ned MD st udi es reveal ed t hat al l t he
cycl i c product s had symmet ri cal st ruct ures (J.
Org. Chem. 2003, 68, 6257-63).
DRUGS & INTERMEDIATES DRUGS & INTERMEDIATES DRUGS & INTERMEDIATES DRUGS & INTERMEDIATES DRUGS & INTERMEDIATES
di -O-myr i st oyl at ed Gaa i nt o Leu-enkep hal i n
est abl i shed a wel l -def i ned -t urn st ruct ure i n
t he molecule (Tet rahedron Let t . 2004, 45, 5623-
5627).
O Conformational analysis of the linear tetramer
of a glucose-derived furanoid sugar amino
acid:
Gaa revealed t hat t he fully prot ect ed t et ramer
h ad a w el l -d ef i n ed st r uct ur e i n CDCl
3
w i t h
r ep eat i n g b - t u r n s (I ), each i n vo l vi n g a 10-
membered ri ng st ruct ure wi t h i nt ramol ecul ar
h yd r o g en b o n d s b et w een NH
i
C= O
i -2
. It s
deprot ect ed versi ons showed aggregat i on i n
or g ani c sol vent s (I I and I I I ) w i t h st r uct ur es
similar t o t hat of t he prot ect ed one
(Tet rahedron Let t . 2004, 45, 3573-3577).
I II III
O 3,4-Di -O-acyl at ed deri vat i ves of f uranoi d
sugar ami no aci ds: 3,4- Di - O- acyl at ed
deri vat i ves of Gaa were synt hesi zed as novel
pept i de bui l di ng bl ocks t o st udy t hei r ef f ect s
on pept i de conf ormat i on. Int roduct i on of t he
O Conformational studies of peptides containing
ci s- 3 - hydr oxy- D- pr ol i ne: Co n f o r mat i o n al
anal ysi s of pept i des cont ai ni ng ci s-3-hydroxy-
D-proline (D-ci s-3-Hyp) by NMR st udies revealed
t hat t he 3-hydroxyl group i n t hi s ami no aci d
p l ays a si gni f i cant r ol e i n t he over al l t hr ee-
d i men si o n al st r u ct u r es o f t h e p ep t i d es
exhibit ing hydroxyl-assist ed t urn st ruct ures, in
pol ar sol vent s, si mi l ar t o t hose f ound i n t hei r
f ur anoi d congener s (J. Or g. Chem. 2004, 69,
7399-7402).
* Organic Synthesis and Synthesis of Natural
Product s
O Total synthesis of (+)-crocacin A: Tot al synt hesis
of t he pot ent ant i f ungal and cyt ot oxi c agent
(+ )-cr ocaci n A has b een car r i ed out , w her e
crucial (Z)-5,6-enoic amide moiet y was built by
st ereosel ect i ve part i al reduct i on of a ski pped
diyne precursor. The diene, t hus obt ained, was
t r an sf o r med i n t o a si l yl ep o xi d e t h at w as
regi osel ect i vel y opened wi t h an azi de i on t o
f u r n i sh an - azi d o - - h yd r o xyal kyl si l an e
i nt ermedi at e. Pet erson el i mi nat i on of t hi s b-
h yd r oxysi l an e comp on en t i n t h e f i n al st ep
result ed in t he format ion of t he (Z)-8,9-enamide
moiet y of t he molecule leading t o a successful
co mp l et i o n o f i t s f i r st t o t al syn t h esi s.
(Tet rahedron Let t . 2003, 44, 4989-4992).
34
O Synt hesi s of -l ct ones: Rad i cal -med i at ed
opening of a chiral t risubst it ut ed epoxy alcohol
using cp
2
Ti Cl furni shed t he 2-met hyl -1,3-di ol
moiet y wit h t he desired st ereochemist ry which
l ed t o a t ot al synt hesi s of (3R,4S,5S,9S)-3,5,9-
t ri hydroxy-4-met hyl undecanoi c aci d -l act one
(I) (Tet rahedron Let t . 2004,45, 7637-7639) and 3,5-
d i h yd r o xy- 2,4- d i met h yl - n - h ep t an o i c aci d
lact one (II) (Arki voc 2005, i i i , 170-178).
(Lys) (x 2.7). In o si t o l sh o w ed excep t i o n al
p rop ert y t o sol ub i l i ze si l i ca (x 5). Desi gned
p yr i d i n e- N o xi d es al so so l u b i l i ze si l i ca
(J.Chem.Sci ., 2004,116,169-174).
O Det ai l ed SEM st udi es shown t hat t he carri er
i mi dazol e si gni f i cant l y enhances t he orderl y
deposit ion of silica at bundle sheat h sit es in t he
l eaf an d t h at t h er e i s a d i r ect co r r el at i o n
bet ween t he si l i con deposi t ed and t he carri er
efficiency. The SEM of t he leaves of rice plant
grown wit h all t he carriers have been secured
and all of t hem show t he expect ed silica upt ake
(biologia plant areem, 2005).
O Acyl azides are valuable synt het ic int ermediat es
in preparat ive organic chemist r y. They undergo
f aci l e t hermal rearrangement t o i socyanat es
from whi ch uret hanes, t hi ouret hanes, ami nes,
u r eas, car b o d i i mi d es can b e co n ven i en t l y
prepared. A new met hod is developed for t he
one-pot oxi dat i on of al dehydes t o acyl azi des
by using Dess-Mart in periodinane and sodium
azi de of 0
0
C. ( Tet Let t ., 2003, 44, 3543-3545).
Tegrahhedron LeH. 2003, 443543-3545.
O A general and pract ical green chemist ry rout e
t o t he Bi gi nel l i cycl ocond ensat i on r eact i on
usi ng CeCl
3
. 7H
2
O as t he cat al yst (25% mol ) i s
d escr i b ed u n d er t h r ee set s o f r eact i o n
condi t i ons et hanol , wat er and sol vent f ree
condit ions (J.Org.Chem. 2003,68, 587-590).
O Enant iomerically pure (S)- and (R)-naft opidil and
(S)- at en o l o l w as syn t h esi zed b y u t i l i zi n g
Jaco b sens Hyd r o l yt i c Ki n et i c Reso l u t i o n
met h o d (Bi oor g .Med .Ch em .2005, 627- 630;
Chem. Let t . 2004, 1212-1213).
O Envi ronment al l y beni gn sel ect i ve met hod f or
t he regenerat ion of carbonyl compounds from
o xi mes an d N,N- d i met h yl h yd r azo n es i n
acet onit rile at ambient t emperat ure of aqueous
media has been carried in excellent yields under
K
5
C
o
W
12
O
40
.3H
2
O (0.01 equiv) cat alysis (Synt hesi s
2003, 1883-1885).
O Synt hesi s of hi ghl y subst i t ut ed t et r ahy-
dropyrans: A propi onat e-deri ved pol yket i de
b ui l d i ng b l ock cont ai ni ng 2-met hyl -1,3-d i ol
moi et y w as b u i l t b y a Ti (III)-med i at ed r i ng
openi ng react i on of a t ri subst i t ut ed 2,3-epoxy
al co h o l p r ecu r so r an d u sed as a co mmo n
st art i ng mat eri al f or t he synt heses of hi ghl y
sub st i t ut ed t et r ahyd r op yr ans, one of t hem
being t he C20-C28 fragment of cyt ot oxic nat ural
p roduct s, p horb oxazol es (Tet r ahedr on 2003,
59, 8613-8622).
O Solubilizat ion of silica: The abilit y of each of
t he coded a-amino acids t o solubilize silica under
ambi ent condi t i ons has been carri ed out by
st andard anal yt i cal procedures t o enabl e t he
desi gn of pept i des t hat coul d sol ubi l i ze si l i ca.
Not ewort hy enhancement was observed wit h
imidazole (lm) (x 5), Hist idine (His) (x 3), Glut amine
(Gln) (x 3.5), Glut amic acid (Glu) (x 2.6) and Lysine
35
O Glycochemistry: New disaccharides were synt hesized from
t he chirons derived from easily and abundant ly available
monosac char i d es as chi r al b ui l d i ng b l ocks. Met al
mediat ed react ions such as RCM prot ocol has been very
ef f i ci ent l y ut i l i zed t o synt hesi ze t he cycl i c pyran ri ng
syst ems, while, anot her met al mediat ed react ion such as
ci s-hydroxyl at i on was l at er used t o convert t hem i nt o
deoxy disaccharides. Spiro saccharides also were prepared
using t he RCM prot ocol on t he sugar-derived chirons.
Similarly, int ramolecular nit rone cycloaddit ion prot ocol
was used for t he const ruct ion of a variet y of isoxazolidine
saccharides, having fused pyran and oxepene ring syst ems.
O Synt hesis of carbo--pept ides and ident ificat ion
of new secondar y st r uct ur es: A n ew ar ea of
ch emi st r y o n car b o - b - p ep t i d es w as i n i t i at ed ,
wherein, C-linked carbo-b-amino acids (Caas) having
carbohydrat es as si de chai ns were prepared and
conver t ed i nt o pept i des. These were t horoughl y
analyzed by ext ensive NMR, MD and CD st udies t o
ident ify new helical st ruct ures, such as, right - and
l ef t - h an d ed 12/ 10- an d 10/ 12- h el i ces i n t h e
p ep t i d es w i t h al t er n at i n g ch i r al i t y an d mi xed
pept ides, while a new helix namely 9/ 11-(11/ 9-)-helix
w as f or t h e f i r st t i me i d en t i f i ed i n a/ b -h yb r i d
pept ides. The cyclic pept ides derived have shown
t h e p r esen ce o f n an o t u b es t h r o u g h t h e TEM
st udi es.
O Synt hesi s of bi oact i ve nat ural product s and
development of new synthetic methods: Synt hesis
of ant i-cancer act ive mocrot riolide class of nat ural
product s, namel y, macrosphel i des (16-membered
l act ones) A, C, E and F was achi eved b y chi ron
approach, usi ng Yamaguchi macrol act oni sa- t i on
met hod. Synt hesis of verbalact one and at t empt ed
synt hesi s and st ruct ure det ermi nat i on of nat ural
product s such as, feigrisolide, cladospilide and iso-
cl adospi l i de, acremonol and acremodi ol resul t ed
in non-nat ural product s, while iso-avenaciolide, iso-
canad ensol i d e and i so-sp or o- t hr i ol i d e ar e t he
o t h er n o n - n at u r al p r o d u ct s t h at h ave b een
synt hesi zed.
Tr i ch l or ot r i azi n e an d zi r con i um ch l or i d e w er e
u t i l i zed as Lew i s aci d s f o r t h e p r o t ect i o n /
deprot ect ion chemist r y, besides being used for t he
ef f i ci en t o n e- p o t mu l t i co mp o n en t co u p l i n g s
r eact i o n s t o p r ep ar e co u mar i n s an d o t h er
gl ycoconj ugat es.
O St ereoselect ive synt hesis of L-733,060
Enant i osel ect i ve synt hesi s of non-pept i di c neuroki ni n
NK1 recept or ant agoni st L-733,060 i s descri bed usi ng
ri ng-cl osi ng met at hesi s as a key st ep, st art i ng f romL-
phenyl gl yci ne.
Tet rahedron Let t ers, 2003, 915-917
O A short, simple and general approach for the
synt hesis of (3S,4S)-3-met hoxy-4-met hyl
amino pyrrolidine and (3S,4R)-3-methoxy-
4-methyl amino pyrrolidine
A general and efficient st ereoselect ive approach for t he
syn t h esi s o f (3S,4S) an d (3S,4R)- 3- met h o xy- 4-
met hylamino pyrrolidines, a part of t he st ruct ure of AG-
7352, a napht hyri di ne ant i t umor agent and qui nol i ne
ant ibact erial compounds has been described.
Tet rahedron Let t ers 2003, 5687-5689
O An ef f i ci ent synt hesi s of pr ot ect ed
( 2 R , 3 R , 4 S ) - 4 , 7 - d i a m i n o - 2 , 3 -
dihydroxyheptanoic acid, a constituent of
callipeltins A and D
Drugs & Intermediates
N
H
O
CF3
CF3
L-733,060
N
N
S
N N
O
MeHN
MeO
COOH
N N
O
MeO
COOH
2HN
F
F
MeHN
36
O Stereoselective synthesis of (-)-cytoxazone
and (+)-5-epi-Cyt oxazone
St er eosel ect i ve synt hesi s of (-)-cyt oxazone an
Immuno mod ul at or and i t s epi mer (+ )-5-epi -
Cyt oxazone has been achieved from 4-hydroxy
p h en yl g l yci n e. They al so f o u n d t o h ave
ant ibact erial act ivit y.
Synt het ic Communicat ions, 2003, 2907
O A versatile and efficient synthesis of (2S)-2-
(hydroxymet hyl )- N-Boc-2,3-di hydro-4-
pyridone
A versat ile and efficient met hod for t he preparat ion
of (2S)-2-(hydroxymet hyl )-N-Boc-2,3-di hydro-4-
p yr i done f r om L-(-)-p henyl al ani ne ut i l i si ng t he
aromat ic syst em as a masked -ket o aldehyde was
devel op ed. The key st ep i n t he sequence i s an
i n t r amo l ecu l ar cycl i sat i o n t o g i ve 2,3-
di hydropyri di n-4-ones
Tet rahedron Let t ers: 2003, 4261-4263
O St ereoselect ive synt hesis of 1,4-dideoxy-
1,4-imino-L-allit ol and formal synt hesis of
(2S,3R,4S)-3,4-dihydroxyproline
A st er eosel ect i ve synt hesi s of 1,4-d i d eoxy-1,4-
imino--allit ol and formal synt hesis of (2S,3R,4S)-3,4-
dihydroxyproline was achieved via t he addit ion of
vi n yl mag n esi u m b r o mi d e t o t h e b en zyl i mi n e
d er i ved f r o m (R)- 2,3- O- i so p r o p yl i d en e
g l ycer al d ehyd e f ol l ow ed b y N-al l yl at i on, r i ng -
closing met at hesis (RCM), and dihydroxylat ion.
O A short est st ereosel ect i ve synt heses of
Chloramphenicol and Thiamphenicol:
A co mmo n st r at eg y f o r t h e syn t h esi s o f (- )-
ch l o r amp h en i co l an d (+ )- t h i amp h en i co l i s
described These ant ibiot ics have been synt hesized
from commercially available 4-nit robenzaldehyde
and 4-(met hylt hio)benzaldehyde in t hree and four
st eps, respect ively.
Tet rahedron:Asymmet r y 2004, 1279-1283
An efficient and st ereoselect ive synt hesis of prot ect ed
(2R,3R,4S)-4,7-di ami no-2,3-di hydroxyhept anoi c aci d, a
const it uent of t he depsipept ides, callipelt ins A and D,
from L-ribose is described.
Tet rahedron Let t ers, 2003, 5645
O St ereoselect ive synt hesis of (-)- and (+)-
pentenomycins using RCM
An effi ci ent synt hesi s of enant i opure (-)- and (+)-
pent enomyci ns are descri bed by reduct i ve i odo
eliminat ion and ring-closing met at hesis (RCM), as
t he key st eps. The fi rst synt hesi s of t he unnat ural
(+)-isomer is described.
Tet rahedron Let t ers, 2003, 5103
N
H
N
H
NH
2HN
NH
OH
OH O
HN
O
OH
O
O
NH2
H
N
O
O
O
N
H
O
MeN
O
MeO
OH
N
H
O
NMe
CONH2
O
NH
O
HN
OH
N
H
NH
NH2
Callipeltin A
N
Boc
OH
O
NHBoc
OH
3 steps
OMe
H
HO
O
O
4 5
NH
H
OMe
H
HO
O
O
4 5
NH
H
O
OH
OH
OH
O
OH
OH
OH
D-Mannose
D-Ribose
(-)-Pentenomycin
(+)-Pentenomycin
N
H
HO
OH
HO
HO
N
H
HO
OH
COOH
and
D-Mannitol
37
O Chiron approach t o (1R,2R,5S,7R)-2-hydroxy-
exo-brevicomin
Chiron approach t o t he synt hesis of (1R, 2R, 5S, 7R)-
2-hydroxy-exo--brevicomin 1, a component of t he
vo l at i l es o b t ai n ed f r o m mal e mo u n t ai n p i n e
b eet l es, Den d r oct on u s p on d er osae h as b een
achieved. Our synt hesis st art ed wit h commercially
avai l ab l e D- Man n i t o l an d i n vo l ved Wi t t i g
oleifinat ion, acid cat alysed one pot hydrogenat ion
and int ernal acet alizat ion as key st eps.
O St er eosel ect i ve synt hesi s of (3 R,4S)- 3-
met hoxy - 4-met hylaminopyrrolidine
An ef f i ci en t st er eo sel ect i ve ap p r o ach f o r t h e
synt hesi s of (3R,4S)-3-met hoxy-4 met hyl ami no
O Stereoselective synthesis of (-)-pestalotin
Th e asymmet r i c syn t h esi s o f (- )- p est al o t i n i s
d escr i b ed u si n g OsO
4
- cat al yzed asymmet r i c
d i h yd r oxyl at i on an d ut i l i zat i on of sub st i t ut ed
aromat ic syst em as masked -ket oest er as t he key
st eps in t he react ion sequence.
ARKIVOC, 2005, 74-82
O Asymmet ric synt heses of (1R, 1R, 5R, 7R)
and (1S, 1R, 5R, 7R)-1- hydroxy- exo-
brevicomin and a formal synt hesis of (+)-
exo-brevicomin:
Asymmet ric synt heses of (1R, 1R, 5R, 7R) and (1S,
1R, 5R, 7R)-1-hydroxy-exo-brevi comi ns 1 and 2,
volat iles of t he male mount ain pine beet le and a
f o r mal syn t h esi s o f (+ )- exo- b r evi co mi n 3, a
component of t he at t ract i ng pheromone syst em
of several bark beet les has been achieved. The key
st eps are Birch reduct ion of commercially available
a-picoline, select ive Wit t ig olefinat ion and Sharpless
asymmet ri c di hydroxyl at i on.
pyrrol i di ne, a part of t he st ruct ure of qui nol i ne
ant ibact erial compound (1a) and t he napht hyridine
ant it umour agent (1b) has been described.
O The first stereoselective synthesis of natural
anhydrophyt osphi ngosi ne Pachast ri ss
amine (Jaspine B):
Th e syn t h esi s o f t h e n at u r al an h yd r o p h yt o
sphingosine pachast rissamine (j aspine B) 1a from
Garner_s aldehyde is described.
O
O
OH
O
O
OH
O
O
OH
O
O BnO
O
H2, Pd/C
aq HCL(cat)
MeOH
D-Mannitol
(1R, 2R, 5S, 7R)-
2-hydroxy-exo- brevicomin
N
O
O
O
O
OH
O
O
OH
5 steps
7 steps
+
(+)-exo-brevicomin
(1R, 1'R, 5'R, 7'R) and (1S, 1'R, 5'R, 7'R)
-1-hydroxy-exo-brevicomins
2ON
OH
OH
NHCOCHCl2
MeS2O
OH
OH
NHCOCHCl2
(-)-Chloramphenicol
(+)-Thiamphenicol
O O
O
H
N
H
MeO NHMe
(R,S)-2
.2HCl
O NBOC
O
H
O O
RHN OR
C
14
H
29
RHN OR
C
14
H
29
+
9 steps
1a R=H
2a R=Ac
1b R=H
2b R=Ac
O
O
OEt
OH
OH
OMe
OH
OMe
O
(-)-Pestalotin
38
O A shor t , st er eosel ect i ve and common
approach for the synthesis of 4,5-disubstitu
t ed -lact ones simplact one B and it s C-5
analogue:
A short , st ereoselect ive, and a common approach
f or t he synt hesi s of 4,5-di subst i t ut ed d-l act ones
si mp l act o n e B an d i t s an al o g u e u si n g Evan s
prot ocol is described.
Bioorganic Medicinal Chemist ry let t ers, 2005, 2085-
2086
O A new approach to (+)-anisomycin
An ef f i ci en t ap p r o ach t o o p t i cal l y p u r e (+ )
deacet yl ani somyci n 2a and a f ormal synt hesi s of
(+ )-ani somyci n 2 have b een achi eved t hr ough
simple and good yielding react ions, st art ing from
1,2:3,4:5,6-t r i - O-i sop r op yl i d en e-D-man n i t ol 3.
Gri gnard react i on and i nt ramol ecul ar cycl i sat i on
react ions are key st eps in our st rat egy.
Tet rahedron: Asymmet r y: Ar t i cl e i n press 2005
O A chi r on appr oach t o (1 R, 2 R, 5 S, 7 S)- 2-
hydroxy-endo-brevicomin:
A chiron approach for t he synt hesis of (1R,2R,5S,7S)-
2-hydroxy-endo-brevicomin 1, a component of t he
vo l at i l es o b t ai n ed f r o m mal e mo u n t ai n p i n e
b eet l es, Den d r o ct o n u s p o n d er o sae h as b een
O St ereoselect ive synt hesis of (2S,7S)-7-(4-
phenoxymethyl)-2-(1-N-hydroxyureidyl-3-
butyn-4-yl)oxepane:
We have achieved a short , efficient st ereoselect ive
synt hesis of 7-membered oxepane derivat ives wit h
p o t en t i al ag ai n st ast h ma. Hi g h l i g h t s o f o u r
synt het ic st rat egy are regioselect ive oxidat ion of a
hydroxyl group and efficient ring closure of an open
chai n al dehyde t o a 2-benzenesul f onyl oxepane
derivat ive wit h PhSO
2
H. Surprisingly t he ci s-isomer
showed bet t er act ivit y t han t he t rans-isomer.
Tet rahedron: Asymmet ry 2005, 935-939
O Stereoselective synthesis of (-)-gabosine C:
An efficient synt hesis of (-)-gabosine C and a formal
synt hesi s of (-)-COTC 4 are descri bed usi ng t he
Nozaki HiyamaKishi (NHK) react ion and RCM as
t he key st eps.
achieved. Our synt hesis st art ed wit h commercially
available D-ribose and involves a Wit t ig olefinat ion,
an acid cat alyzed one-pot hydrogenat ion and t he
int ernal acet alizat ion as key st eps.
Tet rahedron: Asymmet r y 2005, 1611-1614
O
N
O
NH2
OH
O F
H H
(2S,7S)-7-(4-phenoxymethyl)-2-(1-N-hydroxyureidyl-3-butyn-4-yl)oxepane
O
OH
H
3
C
O
O
OH
C
14
H
29
O
O NH
Bn
O
Simplactone B 2
C-5 analogue of
simplactone 3
HO
O
OH
OH
OH
O
O
O
HO
MOMO
HO
O O
OTHP
(-)-gabosine C
O
O
OH
H
D-Ribose
7 steps
(1R,2R,5S,7S)-2-hydroxy
-endo-brevicomin
N
R'
RO OH
MeO
D-(+)-Mannitol
R = Ac, R' = H (+)-anisomycin
R = R' = H (+)-deacetylanisomycin
39
O Ast hma and allergic disorders mit igat ion mission-
Synt hesis of PDE-4 inhibit ors: Ast hma i s a compl ex,
mult ifact orial disease charact erized by reversible airway
obst ruct i on, ai rway-i nf l ammat i on, non-speci f i c ai rway
hyperact i vi t y wi t h a vari et y of pharmacol ogi cal and
en vi r o n men t al ch al l en g es. Cycl i c 3, 5 - ad en o si n e
monop hosp hat e (cAMP) and cycl i c 3, 5 -guanoci ne
monophosphat e (cGMP), are second messengers t hat
are involved in a wide range of physiological processes.
It has been est ablished t hat PDE-4 enzyme is responsible
f or t he breakdown of cAMP/ cGMP i n many t ypes of
i nf l ammat ory cel l s and generat e 5-AMP and 5-GMP
resp ect i vel y, as i nact i ve product s. Thus, t he obvi ous
b i och emi cal con seq uen ce of cAMP sp eci f i c PDE-4
inhibit ion is t he increase in t he int ra-cellular level of cAMP.
Hence, desi gn and synt hesi s of PDE-4 i nhi bi t ors was
undert aken for t he development of pot ent ial drugs for
* APPLIED RESEARCH APPLIED RESEARCH APPLIED RESEARCH APPLIED RESEARCH APPLIED RESEARCH
O DST- DABUR- I I CT col l abor at i ve pr oj ect on
devel opment of pept i de based ant i - cancer
compounds : In t hi s proj ect , several pept i domi met i c
analogs of t he VIP recept or binding inhibit or Leu-Met -
Tyr-Pro-Thr-Tyr-Leu-Lys wer e p r ep ared by i nser t i ng
furanoid sugar amino acids int o t he molecule at various
places. The result ing analogs were t est ed for t heir ant i-
cancer act i vi t i es i n vi t ro, fol l owi ng t he st andard MTT
assay on a panel of human cancer cell lines. One of t he
pot ent analogs was t est ed i n vi vo for t umor regression
on primary colon t umor xenograft ed nude mice, which
showed t hat t he percent age inhibit ion of t umor growt h
cau sed b y t h at p ar t i cu l ar an al og as comp ar ed t o
cont rols on day 21 was 57%. The experiment al result s
su g g est t h at man y o f t h ese an al o g s sh o w ei t h er
r et en t i o n o r en h an cemen t o f b i o l o g i cal act i vi t y
(Tet rahedron 2004, 60, 8329-8339).
t he t reat ment of ast hma. A large number of NCEs were
synt hesi zed and subj ect ed t o t est i ng. 30 NCEs have
shown promising PDE act ivit y, which are under fur t her
i n vest i g at i o n f o r t h e l ead g en er at i o n an d l ead
opt i mi zat i on.
O New rout e ident ificat ion for fragranc e chemicals
(Givaudan, Swit zerland): A collaborat ive proj ect was
i ni t i at ed bet ween IICT and Gi vaudan, Swi t zerl and, f or
t he i d ent i f i cat i on of new synt het i c r out es f or t w o
f r ag r an ce mo l ecu l es an d d evel o p i n g t h em i n t o
economically viable process rout es. Innovat ive chemical
r o u t es f o r t h e Gi vau d an mo l ecu l es ar e al r ead y
est ablished. Simple and high yielding condit ions were
est ablished for reducing double bond, while t he yields
i n t he aci d cat al ysed cycl i sat i on were i mproved f rom
6% t o 40%. Fu r t h er w o r k i s i n g o o d p r o g r ess t o
complet e t he synt hesis.
O Synt hesi s of combi nat or i al l i br ar i es f or t he
evaluat ion as agrochemicals (Dupont , USA): Four
proj ect s were undert aken wi t h DuPont , USA, f or t he
syn t h esi s of l i b r ar i es of NCEs t o eval uat e t h em as
ag r och emi cal s. New ch emi st r y w as d evel op ed f or
prepari ng t he scaf f ol ds and t he t hus made scaf f ol ds
were ef f i ci ent l y convert ed i nt o NCEs, wherei n several
modificat ions were brought about in chemical react ions.
* BIOTRANSFORMATIONS:
IICT has been act ively involved in biot ransformat ions/
biot echnology wit h a view t o develop greener and safer
p r o cesses/ t ech n o l o g i es cat al yzed b y en zymes. In
cont i nuat i on of our ef f ort s t owards t he synt hesi s of
bi ol ogi cal l y i mport ant compounds, new and si mpl e
met hodologies have been developed for t he synt hesis
some drugs, drug int ermediat es and for commercially
i mport ant chi ral compounds.
O Enantiomerically pure -hydroxy nitriles
Op t i cal l y act i ve - h yd r o xy n i t r i l es ar e u sef u l
int ermediat es in t he preparat ion of funct ionalized chiral
synt hons and have wide applicat ions in t he preparat ion
of a l ar ge numb er of nat ur al p r od uct s, ant i b i ot i cs,
serot oni n reupt ake i nhi bi t ors (f l uoxet i ne, dul oxet i ne
et c.) and chiral auxiliaries. Various met hodologies have
been report ed in lit erat ure for t he preparat ion of t hese
ni t ri l es. Nevert hel ess, t here i s a scope f or prepari ng
t h ese o p t i cal l y act i ve co mp o u n d s b y emp l o yi n g
enzymat ic approaches. In t his cont ext , different lipases
Superimposition of the H-bonded regions of the VIP
antagonist (blue) and its analogs (other colors)
40
O
S
NHCH
3
(S)-Duloxetine
US patent Appl. No. 10/393,406
Tetrahedron Lett. 2003, 44, 4783
O Amino alcohols
Op t i cal l y act i ve seco n d ar y ami n o al co h o l s ar e
i mport ant i nt ermedi at es f or asymmet ri c synt hesi s of
b i ol og i cal l y act i ve sub st an ces such as ad r en er g i c
agent s, ant ihelmint ics, ant idepressant s, -blockers and
an t i ar r h yt h mi c ag en t s. A n ew on e-p ot en zymat i c
resolut ion met hod has been developed which provides
an al t ernat e short synt het i c rout e for t he preparat i on
of enant iopure propranolol and sot alol.
US Pat ent Appl. No. 11/ 022,275
Tet rahedron: Asymm, 2005, 16, 1485
S-Levami sol e
Bioorg. Med. Chem. Let t . 2005, 15, 613
Tet rahedron: Asymm. 2004, 15, 3939
have been invest igat ed for t he kinet ic resolut ion of 3-
aryl -3-hydroxypropane ni t ri l es by t ransest eri f i cat i on
process. The resolved hydroxy nit riles have been ut ilized
f or t he preparat i on of f l uoxet i ne and dul oxet i ne. Thi s
ap p r oach has b een ext end ed f or chemoenzymat i c
synt hesi s of di f f erent -bl ockers and al so GABOB and
car t i ni ne. Fur t her, t hi s met hod ol ogy has al so b een
ut ilized for t he preparat ion of opt ically pure -hydroxyl
ni t ri l es and t hei r appl i cat i on t owards t he synt hesi s of
l evami sol e.
US pat ent Appl. No. 10/ 393,406
Tet rahedron Let t . 2003, 44, 4783
US pat ent Appl. No. 10/ 393,406
Tet rahedron Let t . 2003, 44,4783
Bioorg. Med. Chem. Let t . 2004, 14,4581
O Azido alcohols
Azi doal cohol s are commerci al l y usef ul i nt ermedi at es
f or di f f erent pharmaceut i cal l y i mport ant compounds.
A si mpl e and hi ghl y ef f i ci ent met hodol ogy has been
developed for t he preparat ion of opt ically act ive -azido
al co h o l s, w h i ch h ave b een u t i l i zed t o w ar d s t h e
preparat ion of biologically act ive amino alcohols such
as t embamide, aegeline and denopamine.
HO OCOR
OCOR
HO OCOR
OCOR
R= C
15
H
31
H
N
O
OH
MeO
H
N
O
OH
MeO
H
N
OH
MeO
OCH
3
OCH
3
Tembamide
Aegeline Denopamine
N
N
S
COOH H
2
N
OH
COOH N
OH
Cl
-
(R) - GABOB
Carnitine hydrochloride
+
O
H
N
OH
(S)- Propranolol
H
N
OH
N
H
S
Me
O
O
(S)-Sotalol
NHCH
3
O
F
3
C
(R)-Fluoxetine
PCT Appl. No. WO 02/057475
O
S
NHCH
3
(S)-Duloxetine
US patent Appl. No. 10/393,406
Tetrahedron Lett. 2003, 44, 4783
(S)-and (R)-O-(4-met hoxyphenyl)-glycidol
Tet rahedron: Asymm. 2005, 16, 1485
41
Indian Pat ent Applied.
A large number of organisms have been screened for
t hi s t ransf ormat i on and some of t he posi t i ve st rai ns
are being invest igat ed for t heir pract ical ut ilit y in t his
t ype of t ransf ormat i on. Some mi crobes bel ongi ng t o
Candida, Pichia, Rhodot orula, and Gordonia sp. have been
invest igat ed for t he product ion of brassylic acid from
t ridecane and found t hem t o be posit ive.
O Pre-Biot ech Incubat or Process Generat or
(PBG)
This cent re, which is in t he process of complet ion, will
house f aci l i t i es f or carryi ng out bi ot echnol ogy based
research. Thi s wi l l al l ow f er ment at i on and enzymat i c
r eact i on s t o b e car r i ed out at b en ch scal e. It al so
i n cl u d es au xi l i ar y f aci l i t i es f or cel l cu l t u r e, med i a
preparat ion and relat ed down st ream facilit ies.
O OO OO Design and Synthesis of Anticancer Agents:
Molecular Recognition of DNA
In recent years t here has been considerable int erest in
t he design and development of DNA int eract ive ligands
t hat are capabl e of bi ndi ng t he DNA i n a sequence
sel ect i ve manner. These gene-t arget i ng comp ounds
have pot ent ial in t he t herapy of genet ic based diseases
i ncl udi ng some cancers, di agnost i cs and val i dat i on of
DNA seq u en ces. Nat u r al l y o ccu r r i n g p yr r o l o [ 2,1-
c] [ 1,4] b en zo d i azei p n es (PBDs) h ave at t r act ed t h e
at t ent i on of many researchers l argel y because of t he
p ot ent ant i cancer act i vi t y exhi b i t ed i n most of t he
co mp o u n d s w i t h t h i s r i n g syst em. As a p ar t o f
cont i nui ng research on desi gn and synt hesi s of new
an t i can cer ag en t s, a n u mb er of h yb r i d mol ecu l es
cont aining PBD ring syst em have been synt hesized t o
i mp r o ve u p o n t h e b i n d i n g ab i l i t y an d seq u en ce
select ivit y. During t his process some new and efficient
synt het ic st rat egies including t he solid phase synt hesis
have also been developed.
Some of t he not abl e f i ndi ngs of t hi s research act i vi t y
i ncl ude t he l i nkage of DNA i nt eract i ve moi et i es l i ke
napht hal i mi des and al kyl ami no compounds, pyrene,
acr i d o n e, f l u o r o ar yl su b st i t u t ed p yr i mi d i n es an d
benzi mi dazol es t hrough di f f erent t ype of spacers. A
number of compounds from t he new cl ass of hybri ds
have promising i n vi t ro ant icancer act ivit y wit h efficient
DNA binding abilit y and base pair sequence select ivit y.
Few new molecules are undergoing i n vi vo st udies for
ant icancer act ivit y.
O Intermediate for antitumour compound AG
7352
Tet rahedron Let t . 2004, 45, 8057
Co mp o u n d AG 7352 cl ai med t o p o ssess eq u al o r
superi or ant i t umor act i vi t y t o t hose of ci spl at i n and
et oposi de agai nst human breast , ovari an and col on
cancers implant ed in nude mice. The st ereo chemist ry
of 3-met hoxy-4-met hyl aminopyrrolidine group at t he
C-1 posit ion of AG-7352 is responsible for it s ant it umor
act ivit y. An efficient chemoenzymat ic met hod has been
devel oped f or t he synt hesi s of 3-met hoxy-4-met hyl
amino pyrrolidine in high enant ioselect ivit y.
O OO OO Microbial oxidat ion of long chain alkanes
The t ermi nal oxi dat i on of l ong chai n al kanes such as
dodecane and t ri decane (pet rochemi cal f eed st ocks)
provides t he indust rially import ant dicarboxylic acids.
Microbial oxidat ion of such alkanes is a pot ent ial and
versat i l e met hod.
COOH HOOC
Brassylic acid
N N
S N
N
MeHN
CO
2
H
AG-7352
MeO
O
N
R
1
MeO NHR
(S,S)
R=Me, R
1
=H
R= R
1
=Boc
42
O OO OO Design and Synt hesis of Ant it ubercular
Agents
Th e r esear ch i n d r u g r esi st an t t u b er cu l o si s h as
generat ed a renewal of int erest in a st rat egic search for
Bioorg. Med. Chem. Let t . 2005, 15, 1927-1929
Bioorg. Med. Chem. Let t . 2005, 15, 1923-1926
O IP Licensing
IICT/ CSIR ent ered i nt o an excl usi ve agreement wi t h
M/ s. Ind US Pharmaceut i cal s, USA, for l i censi ng of US
pat ent s [US 6884799, US 6800622, US 6362331 & US
6683073 and US pat ent applicat ion US2004/ 0192678A
of Dr. Ahmed Kamal , et al ] wi t h respect t o phar ma-
ceut icals, drug discovery and drug development of new
molecule ent it y.
Cont ract Value: US $ 1,00,000 (including pat ent cost s)
followed by milest one payment s at different st ages.
prot ot ype leads. Many st udies are being at t empt ed t o
devel op new ant i -t ubercul ar compounds t o resol ve
some of t he p r ob l ems wi t h t he cur r ent l y avai l ab l e
ant it ubercular drugs. In t his connect ion a proj ect was
i ni t i at ed i n t hi s l aborat ory t o desi gn and synt hesi ze
st r uct ur al l y mod i f i ed new mol ecul es b ased on t he
exi st i ng l eads. In t hi s ef f ort a number of compounds
such as pht halimido, napht halimido linked phenazines,
t h i o l act o n es, b en zo t h i ad i azi n es, co u mar i n es an d
qui nal ones have been synt hesi zed and eval uat ed f or
t h ei r an t i t u b er cu l ar act i vi t y. Amo n g st t h ese,
b en zo t h i ad i azi n e b ased scaf f o l d s h ave exh i b i t ed
promi si ng ant i mycobact eri al act i vi t y.
N
N
O
H
H
3
CO
O
O (CH
2
)
n
n = 3-5
R = H, N-methylpiperazine
R
H
N
N
R
N
N
O
H
H
3
CO
O
O
(CH
2
)
n
N
H
n = 3, 4
N
N
O
H
H
3
CO
O
O
(CH
2
)
n
N
H
n = 3, 4
N
N
O
H
N
N
O
H
H
O
OCH
3
O
H
3
CO
n = 1, 3
n
N
N
H
N
N
N N Cl N
O
O
( )
2
( )
n
Cl
S
O
O
S
OCH
3
O
n
CH
3
H
3
C
N
N
O
H
H
3
CO
O
N
H
N
O
O
O
N
O
O
43
Esfenvalerate
IICT has devel oped a t echnol ogy f or manuf act ure of
chiral esfenvalerat e an insect icide wit h export pot ent ial
and Indi an market . The i nt roduct i on of si ngl e i somer
pest icides has become a requirement t o achieve higher
act ivit y, lower requirement per hect ar and minimizat ion
o f r esi d u al t oxi ci t y. A b en ch scal e p r o cess w as
devel op ed and t ransf er red t o Vi rchow Lab orat or i es
Lt d., Hyderabad and Bharat Rasayan Ld., New Delhi.
The si gni f i cant achi evement i n t he process i s ki net i c
cont rol / dynamic resolut ion t echnique t hat gives high
chi ral puri t y product . Thi s cl ai m has been appl i ed for
grant of pat ent in PCT, India.
Indoxacarb
Pr ocess f or man uf act ur e of In d oxacar b i s n ear i n g
complet ion. The proj ect was sponsored by a consort ium
of Pest icide Formulat or and Manufact urers Associat ion
of India (PFMAI). The t echnology will be t ransferred soon.
Bio-Pest icides from Neem
Market need based t echnol ogy upgraded process t o
prepre high azadiracht in was developed on t he bench
scale and t ransferred t o Myt hri Agro Indust ries, Kerala.
Th e exp or t g r ad e azad i r ach t i n r eq u i r ed st r i n g en t
specificat ion requirement s such as 40% 5 azadiracht in
cont ent (assay by HPLC & PTLC), charact erizat ion of ot her
const i t uent s p r esent ab ove 0.2%, st ab i l i t y d at a of
several export grades of azadiracht in on st orage; t oxicit y
dat a for applicat ion in healt h care product s preparat ion;
variat ion of azadiracht in cont ent in various variet ies of
neem seeds and kernel s procured at di f f erent agro
climat ic condit ions. Much of t he crit ical dat a required
for ot her t han agrochemical use was developed at IICT
and t he work has already been pat ent ed in t he US, EP,
Canada, Japan and Aust ral ia.
AGROCHEMICALS AGROCHEMICALS AGROCHEMICALS AGROCHEMICALS AGROCHEMICALS
Director, IICT (left) is seen with the project team of the process
for biopesticide formulation from neem seed/kernel
Field Pheromone Lures developed by IICT
Bio-pest icides t echnologies developed on bench scale
ar e f or an n on a an d kar an j a an d t r an sf er r ed t o Sr i
Bi ot ech, Hyderabad. These t echnol ogi es meet due t o
meet ing of specificat ion requirement s for export .
*PHEROMONE CHEMICALS
Insect pheromones wi t h t hei r uni que mode of act i on
offer an excellent pot ent ial for monit oring and cont rol
of i nsect pest s and are consi dered as an i mport ant
co mp o n en t i n In t eg r at ed p est man ag emen t
programmes. Insect pheromones are highly specific in
act i on, l ow t oxi c t o human, easi l y bi odegradabl e and
l eave negl i gi bl e or zero resi dues i n t he envi ronment .
Cont inuous research on Isolat ion and ident ificat ion of
p h er o mo n e syst ems o f p est s h avi n g eco n o mi c
i mp o r t an ce p er t ai n i n g t o In d i a an d syn t h esi s o f
commerci al l y si gni f i cant pheromone component s i n
t h ei r p u r est f o r m i s essen t i al f o r p r act i cal
i mpl ement at i on of t echnol ogy. In t hi s di rect i on, t he
pheromone group at IICT as a package programme is
act i vel y en g ag ed i n al l asp ect s o f p h er o mo n e
t echnology right from isolat ion, ident ificat ion, synt hesis
of pheromone component s, di spenser devel opment
and finally t he field applicat ion.
O I sol at i on and I dent i f i cat i on of Pher omone
Component s: Pheromone syst ems of t en insect
species of Indian origin have been ident ified during
t he previous years. Current ly work on isolat ion and
i d en t i f i cat i o n o f p h er o mo n e syst ems o f
p omeg r an at e f r u i t p est s Eu ci d oma mat er n al /
fullonia and Deudorix isocrat es is under progress.
O Synt hesi s of Pher omone Component s:
Ph er o mo n e co mp o n en t s o f t h e f o l l o w i n g
co mmer ci al l y i mp o r t an t cr o p p est s w er e
syn t h esi zed at 25 g m b at ch si ze an d t h e
t echnol ogi es are ready for t ransfer t o i ndust ry:
44
Insect Pheromone components Crop
1. Chi l o sacchari phagous i ndi cus Z
13
Oct adecenyl acet at e (7) Sugarcane
(Sugarcane int er node borer ) Z
13
Oct adecenol (1 )
2. Scirpophaga excerpt alis E
11
Hexadecenal (70) Sugarcane
(Top shoot borer) Z
11
Hexadenol (30)
3. Chilo infesculat us Z
11
Hexadenol Sugarcane
(Earl y shoot borer)
4. Plut ella xylost ella Z
11
Hexadecenyl acet at e (10) Cabbage &
(diamond back mot h) Z
11
Hexadecenal (10 ) Caul i fl ower
Z
11
Hexadecenol (0.1)
5. Leuci nodes orbonal i s E
11
Hexadecenyl acet at e (10) Brinj al
(Brinj al fruit & Shoot borer) E
11
Hexadecenol (1)
6. Hel i coverpa armi gera Z
11
Hexadecenal (97) Cot t on
(Ameri can bol l worm) Z
9
Hexadecenal (3)
7. Pect i nophora gossypi el l a Z
7,
Z
11
Hexadecadienyl acet at e (50) Cot t on
(Pink bollworm) Z
7
,E
11
Hexadecadienyl acet at e (50)
8. Earias vit ella E
10
,E
12
Hexadecadienal (10) Cot t on
(Spiny bollworm) Z
11
Ooct adecenal (2)
Z
11
Hexadecenal (2)
9. Aproaerema modi cel l a E
7
Decadienyl acet at e (20) Groundnut
(Groundnut l eaf mi ner) Z
7
Decadienyl acet at e (100)
Z
7
Decenyl acet at e (14)
10 Musca domest i ca Z
9
Tricosene Domest i c
(Common housef l y)
O Dispenser Development : Ident i f i cat i on of sui t abl e
di spenser i s i mport ant for t he successful rel ease rat es
of pheromone blend over a period of t ime during t he
crop cycle. Trap cat ch dat a, release rat es and persist ence
of p heromone b l end i n t he di sp enser are t aken as
paramet ers f or t he sel ect i on of proper di spenser f or
part i cul ar i nsect pest . Sol vent pret reat ment and l ure
i mpregnat i on met hods f or each di spenser t ypes are
al so st an d ar d i zed w h i l e i d en t i f yi n g t h e su i t ab l e
dispenser. Ant i oxidant was always added t o t he lures
in order t o prot ect t he pheromone component s from
l i ght , t emperat ure et c. The fol l owi ng i s t he summar y/
achievement s of t he work carried out during 2003-2005
45
S.No. Insect Dispenser Type
1. Groundnut l eaf mi ner Pl ast i cvi al
2. Pink bollworm Plast ic vial
3. American bollworm Yellow/ whit e rubber sept a
4. Sugarcane i nt ernode borer Bl ack rubber sept a
5. Spiny bollworm Green rubber sept a
6. Brinj al fruit and shoot borer Rubber sept a
7. Diamond back mot h Rubber sept a
Field Evaluat ion and Popularizat ion: Field evaluat ion of synt hesized component s is t he crucial and most import ant
st ep t o bring t he developed t echnology t o t he end user for t he benefit of societ y. This challenge was t aken up at
village level basis in farmers fields wit h t he help of various Agricult ural universit ies, NGO groups and ICAR inst it ut es.
Laborat ory synt hesized pheromone lures were placed in cost effect ive t rapping devices/ t raps designed (part icularly
f or groundnut l eaf mi ner) and prepared wi t h l ocal l y avai l abl e raw mat eri al . Di f f erent t rap t ypes were desi gned
depending upon t he size and flight act ivit y of par t icular insect pest . Weekly t rap cat ch dat a was recorded in different
t rap t ype t o sel ect t he best sui t abl e t rap f or each t arget ed i nsect The vari ous f i el d experi ment s conduct ed at
different locat ions are summarized below.
S.No. Insect Crop Location Mode of Cont rol Collaborating
Inst it ut e/ NGO
1.
2.
3.
4.
5.
Yellow
St emborer
Gram Pod
Borer
Groundnut
leaf miner
Sugarcane
i nt ernode
borer
Spiny boll
worm
Rice
Cot t on
Groundnut
Sugarcane
Cot t on
West Godavari (A.P.)
Nizamabad (A.P.)
Warangal & Ni zamabad
(A.P.)
Dhul e (Maharasht ra)
Mahboobnagar and Nal gonda
(A.P.)
Dindivanam (TN)
Coi mbat ore ( TN)
Mahaboob nagar (A.P.)
Moni t ori ng
Mass
t rappi ng
Moni t ori ng
Moni t ori ng
and Mat i ng
Di srupt i on
Moni t ori ng
and Mass
t rappi ng
- do -
Moni t ori ng
and Mass
t rappi ng
Moni t ori ng
& Mass
t rappi ng
- do -
Di rect orat e of
Ri ce Research
(DRR)
PEACE (NGO)
MPKV Dhule
IICT SDDPA
and KVK
(NGO)
NRCG,
Junagadh
Raj ashree
Chemicals Pvt .
Lt d.
MPKV, Dhule
IICT
P PP PPheromone Chemicals heromone Chemicals heromone Chemicals heromone Chemicals heromone Chemicals
Agrochemicals
46
The feed back from t he farmers was encouraging and
t he farmers during t he farmers meet were found eager
and fully co-operat ive t o adopt pheromone t echnology
for t he pest management .
O OO OO Qual i t y Assessment : Su ccessf u l ap p l i cat i on of
pheromone t echnology in IPM depends on t he purit y
an d sp eci f i c r at i o o f each o f t h e p h er o mo n e
component of t he specific blend. Slight variat ion in t he
purit y or t he blend rat io may influence t rap cat ches in
t he field. Hence, a careful check / qualit y assurance of
t he product i s needed at t he l aborat ory l evel , bef ore
being brought in t o t he market . Laborat ory evaluat ion
f o r t h e p r esen ce o f p h er o mo n e co mp o n en t s b y
analyt ical met hods before and aft er field exposure of
t h e l u r e i s i mp o r t an t t o ascer t ai n t h e ef f i cacy
persist ence of pheromone formulat ions. Sophist icat ed
analyt ical t echniques like Gas Chromat ograph (GC) and
GC-linked Mass Spect romet er (GC- MS) are employed
for t he purpose of analysis. St ruct ure confirmat ion and
puri t y prof i l es of t he synt het i c i nt ermedi at es of t he
p r o cess t ech n o l o g y ar e d o n e b y st an d ar d
spect roscopic met hods (NMR, IR, MS and GC). This also
h el p s i n avo i d i n g t h e u sag e o f sp u r i o u s l u r es.
Pheromone group at IICT regularly provides it s service
t o Depar t ment of Agricult ure (Govt . of A.P.) and ot her
Pr i vat e en t r ep r en eu r s t o at t ai n q u al i t y assu r an ce
cert ificat ion for t he different pheromone lures.
OInt ernat ional Collaborat ion : Pheromone group has
est ab l i sh ed sever al co l l ab o r at i ve l i n kag es w i t h
int ernat ional research inst it ut es and universit ies. TNO
t he Net herl ands, was t he f i rst col l aborat i ve i nst i t ut e
w h i ch h el p ed i n est ab l i sh i n g t h e r eq u i r ed
elect rophysiological equipment and t he expert ise in t he
f i el d o f p h er o mo n e r esear ch . Sever al su ccessi ve
l i n kag es w i t h Dep ar t men t o f Bi o l o g i cal Or g an i c
Chemi st ry IIQAB/ CSIC Spai n under DST programme
an d Un i ver si t y o f Keel e U.K. u n d er DFID h i g h er
educat i on l i nks al so hel ped f or successf ul t ransf er of
expert ise. During t his period t he CID-CSIC, Barcelona,
Spain research programme wit h t he support of Minist ry
of Spain and Universit y of Keele, UK programme under
sp o n so r sh i p o f Br i t i sh Co u n ci l ar e act i vel y
i mpl ement ed.
O Tr ai ni ng Pr ogr ammes Or gani zed: Tr ai n i n g i n
p h er o mo n e l u r e p r ep ar at i o n an d i mp r eg n at i o n
t echniques is provided t o ent husiast ic personnel from
Go ver n men t (NCIPM, Del h i ) No n g o ver n men t
organizat ions and indust ry (Raj ashree Sugars Pvt . Lt d.)
o n p aymen t an d n o n p aymen t b asi s i n o r d er t o
popul ari ze pheromone t echnol ogy.
6.
7.
8.
Brinj al
shoot and
f rui t borer
Di amond
back mot h
Pink
bol l worm
Brinj al
Cabbage
Cot t on
Bhuvaneswar (Ori ssa)
Rangareddy (A.P.)
Rangareddy (A.P.)
Rangareddy &
Mahaboob nagar (A.P.)
Moni t ori ng
& Mass
t rappi ng
- do -
Moni t ori ng
&Mass
t rappi ng
Moni t ori ng
& Mass
t rappi ng
- do-
IIHR
IICT
IICT
MPKV
IICT
47
O Value upgradation and Byproduct Utilit y for n-But ylbenzene
SPECIALITY AND FINE CHEMICALS SPECIALITY AND FINE CHEMICALS SPECIALITY AND FINE CHEMICALS SPECIALITY AND FINE CHEMICALS SPECIALITY AND FINE CHEMICALS
applicat ion for resolut ion of 1-arylalkymaines in 74-99%
enant iomeric puri t y has been demonst rat ed. This work
finds applicat ion in manufact ure of single isomer drugs
an d p est i ci d es b y d i ast er eo mer i c cr yst al l i zat i o n
met hod.
O New Photolabile Molecules
Phot olabile prot ect ing group find applicat ion in biology
for st udy of biological processes t hrough labeling. The
st udy makes use of t riggering t he molecule wit h light
and t rack t he product wit h det ect ion at 350 nm and
400 n m. A n ew ef f i ci en t Bi s(4,5-d i met h t oxy-2-
nit rophenyl) et hylene glycol prot ect ing group has been
synt hesi zed and shown i t s p ot ent i al f or b i ol ogi cal
appl i cat i on.
O St rat egi c Mat eri al s f or Manuf act ure of
Photoresists
Ph o t o r esi st s ar e u sed i n man u f act u r e o f
mi croel ect roni cs requi red for devel opi ng st rat egi cal l y
import ant inst rument s. Such mat erials are not available
in public domain for use. Hence, IICT has t aken up t his
act i vi t y and prepared phot o act i vat i ng compounds
(PAC) and filed several pat ent s world over. This work is
done in collaborat ion wit h several ot her inst it ut es (NCL,
Pune, Def ence Depart ment s, et c.) t o f ormul at e t hen
before t hey are found suit able for end use.
O Design and Development of New Chiral
Resolving Agents: Phthalate Esters of Sugar-
Derivatives
Several aci di c chi ral resol vi ng agent s deri ved f rom
carb ohydr at e t emp l at es have b een desi gned. Thei r
n - Bu t yl b en zen e i s a b yp r o d u ct o b t ai n ed i n t h e
manufact ure isobut ylbenzene, t he key raw mat erial for
ant i -i nf l ammat or y dr ug Ib up r of en. Ab out 250 MT /
annum of n-but yl benzene i s obt ai ned i n t he process.
IICT h as d evel o p ed a p r o cess t o man u f act u r e si x
p r o d u ct s n amel y Bu t yr o p h en o n e, 1- p h en yl n -
but ylamine (recemic) (R)1-phenyl n-but ylamine (1), (S)1-
p henyl b ut yl ami ne (2), 4-n-But yl ani l i ne (3)and 2-n-
b u t yl an i l i n e (4), w i l l b e avai l ab l e i n co mmer ci al
quant i t i es. The chi ral versi ons of t he same i s l i kel y t o
f i nd market i n drug di scovery research as a resol vi ng
agent and development of new chiral scaffolds.
(3) (3) (3) (3) (3)
48
Fluoroquinolones- Ant ibact erial agent s
APPLIED RESEARCH
O 2,2,2-Trifluoroet hanol (TFE)
TFE i s an i mport ant f l uoroorgani c compound used as
heat absorpt i on l i qui d i n pumps, an i nt ermedi at e f or
anaest het i c desf l urane et c. IICT has ent ered i nt o an
agreement wi t h M/ s. Navi n Fl uori ne Indust ri es, Surat ,
on non-excl usi ve basi s t o devel op a cat al yt i c process
f or TFE st ar t i n g f r o m HCFC- 133a. Th e IICT h as
successf ul l y devel oped and demonst rat ed a l ab scal e
process on 250g scal e and submi t t ed demonst rat i on
r ep or t t o M/ s. Navi n Fl uor i ne. The p r oj ect i s und er
implement at ion by t he firm.
O Hept afluoropropane (FM-200)
Hept afluoropropane (HFP) is a hydrofluoro carbon, has
been accept ed world over for many applicat ions due t o
it s zero ODP, low GWP and t oxicit y and is one of t he best
ch emi cal su b st i t u t es f o r h al o n s. HFP h as w i d e
applicat ions where halon-1301 was used in t he past .
IICT has ent ered int o an agreement wit h M/ s. Cent re for
Expl osi ve and Envi ronment Saf et y (DRDO) Del hi f or
Development of process for HFP on non-exclusive basis.
An opt imized process is developed on bench scale and
pl anned t o demonst rat e duri ng Oct ober-November
2005. CFEES i s l ooki ng f or an i ndust r i al p ar t ner f or
commerci al i zat i on of process.
O 1,1,1-Trifluoro,2,2-dichloroet hane (HCFC-123)
It i s a hydrof l uorochl orocarbon ai med at usi ng as an
int ermediat e range subst it ut e for banned chlorofluoro
arbons. HCFC-123 is used as refrigerant foam blowing
FLUOROORGANICS FLUOROORGANICS FLUOROORGANICS FLUOROORGANICS FLUOROORGANICS
ag en t . Th e p r o cess f o r HCFC-123 i s d evel o p ed at
l aborat ory scal e and ready f or rel ease. Upscal i ng of
p r o cess o n p i l o t p l an t scal e may b e t aken u p o n
sponsorshi p bai s.
O HFC-134a
HFC-134a pilot plant st udies have been complet ed
sat i sfact ori l y. A commerci al l y accept abl e qual i t y HFC-
134a product (99.8%) i s produced. Al l t he t echni cal
informat ion is compiled and submit t ed demonst rat ion
report .
O BASIC RESEARCH
The synt hesis of fluorinat ed het erocyclic molecules of
b i ol ogi cal i mp or t ance wer e p l anned and execut ed
under basi c r esearch programme. The cont r i but i on
t owards basi c research resul t ed i n good number of
publicat ions and pat ent s. Some of t hem are highlight ed
below:
Lab-scale unit for Fluoroorganics process development
Bench scale unit for fluoroorganics process development
N
N
N
NHCH
3
O O
F
C H
3
Ar
Et
NHCH
3
F
H
3
C-N
O O
N
N
Ar
H
NHCH
3
F
O O
Et
N H
3
C-N
NH
R
R
1
NHCH
3
F
O O
Et
N H
3
C-N
NH
CF
3
N
H
N
Ar
O
2
N
CF
3
N
H
O
2
N NH
R
R
1
CF
3
N
H
O
2
N NH
(CH
2
)
n
(CH
2
)
n
49
O 16 compounds sent t o Bayer Crop Science,
Germany
(Herbicidal, Fungicidal, Insect icidal)
O Benzo[b]furans
O Quinazolinones
Tot al compounds = ~ 50
Synt h. Commun. 32, 2467 (2002)
J Fluorine Chem. 124, 203 (2003)
Product pat ent s - 2
Process pat ent s - 3
O Benzoxazepines
(Cholest erol regulat ing agent s)
O 1,3-oxazino[5,4-b] Indoles
(Synt hon for Benzoxazepines)
Tet rahedron 60 (2004) 12231-12237
Fluoroorganics
R
NH
2
CF
3
CONH
2
CONH
2
CF
3
N
H
NH
H
R'
O
R
CONH
2
+
MnO
2
MnO
2
N
NH
CF
3
R
O
CONH
2
R
1
R
NH
2
CF
3
CN
CN
R
N
H
NH
R'
H
O
CONH
2
F
3
C
N
NH
R
F
3
C
O
CONH
2
R
1
J Flourine Chem. 118, 73 (2002)
Tet rahedron 61 (2005) 3999-4008
(Synthon for Benzoxazepines)
N
O
O
CF
3
R
R"
CN
R'
H
COOH
CF
3
NH
2
CN
CN
R
PhMgBr
CF
3
NH
2
CN
R
Ph
NH
+
(Major)
R
NH
2
CN
NH
Ph
F
3
C
(Minor)
CF
3
NH
2
CN
Ph
OH
H
Ph
CF
3
NH
2
CN
Ph
O
Ph
Z
n
(
B
H
4
)
2
50
*Applied Research
In n o vat i ve p r o cesses emp l o yi n g cat al yst s w er e
developed for t he first t ime which were unique in nat ure
i n al l r esp ect s, b asi c & en g i n eer i n g , an d t h ese
t echnol ogi es opened up new front i ers i n t he areas of
Asymmet ric synt hesis, Solid acid-bases and Oxidat ion.
The new cat alyt ic mat erials perform cat alyt ic react ions
t o achi eve t he hi ghest possi bl e at om economy i n an
effort t o realize cut t ing edge t echnologies and t o meet
st r i ng ent envi r onment al sp eci f i cat i on i n p ol l ut i on
ab at emen t . Th e f o l l o w i n g p r ocess t ech n o l o g i es
culminat ed out of t he effort s in t his direct ion.
O Synt hesis of TBBA
Syn t h esi s o f TBBA, a f i r e r et ar d an t h as b een
demonst rat ed t o BILT Indust ries on a lab scale in bat ch
mode. This process is a mimic of haloperoxidase enzyme
observed in nat ure, ut ilising bot h t he at oms of bromine
molecule. This is an unique t echnology wit h t he cat alyst
developed by IICT. Cont inuous pilot plant st udies wit h
a cap aci t y o f 1.2 t o n n es p er d ay ar e co mp l et ed .
Commercial plant wit h t he capacit y of 10,000 t pa is being
set up, based on t he t echnol ogy devel op ed by IICT.
(Sponsored by : M/ S. Solaris)
O Select ive air oxidat ion of t oluene t o benzal
dehyde
Select ive air oxidat ion of t oluene t o benzaldehyde has
been demonst rat ed t o M/ s. Vinat i Organics Lt d. The pilot
plant st udies are at an advanced st age for compilat ion
of dat a t o set up commercial plant by Vinat i Organics
Lt d. wit h t he capacit y of 15,000 t pa.
O Solid acid cat alyst s for nit rat ion
Fri edel -Craf t s react i ons are very i mport ant t o obt ai n
i nt er med i at es f or d r ug s, p est i ci d es, p er f umes and
f ragrances, et c. The maj or disadvant ages encount ered
wit h t he use of classical AlCl
3
and H
2
SO
4
include corrosion,
envi ronment al l y unf ri endl y and expensi ve due t o t he
r eq u i r emen t o f excess o f r eag en t an d w ast e b y-
product s.
Nit rat ion of t oluene: The most significant achievement
is t he select ivit y i.e., t he nit rat ion of t oluene provided a
product mixt ure cont aining >60% p-isomer as against
t he 34% by convent ional met hod. The present process
has been demonst rat ed t o M/ s. Vasant Chemicals Lt d.
Pi l o t p l an t st u d i es f o r co n t i n u o u s p r o cess ar e
complet ed and due for demonst rat ion. Sponsored by
Vasant Chemicals Lt d. and Deepak Nit ri t es Lt d.
O Development of LPG gas sensor using Nano
technology (DST, New Delhi)
Nan osi zed Sn O
2
p ow d er s w er e syn t h esi zed u si n g
ani oni c sur f act ant as t empl at e. The par t i cl e si ze was
cont rolled in t he range bet ween 4 12 nm wit h a BET
surf ace area of 125m
2
g
-1
.Thi ck f i l m LPG sensor was
fabricat ed using t he synt hesized SnO
2
nanopowder and
it s elect rical response of t he sensor t o LPG t o 200 ppm
was st udied by sensit ivit y measurement .The Sensit ivit y
of nano - SnO
2
was hi gh compared t o convent i onal
SnO
2
powder at t he same operat ing t emperat ure.
O OO OO Nanost ruct ured Semiconduct ing Oxide
based mat er i al s f or devel opment of
Ammoni a Gas Sensor. (Depar t ment of
Atomic Energy)
Meso p o r o u s Zi n c o xi d e w as i d en t i f i ed as g o o d
candidat e for ammonia gas sensing synt hesized by Sol-
gel rout e wit h part icle size of 8 nm which increased t o
14 nm at elevat ed t emperat ure of 500
o
C. Gas Sensing
charact erist ics were carried using t he synt hesized ZnO
powder t owards NH
3
gas. Furt her ef f ect of addi t i ves
i.e.,choice of addit ives on t he bases of different chemical
react ions bet ween t he sensor and t est gas, it s select ivit y
and fabri cat i on of prot ot ype of sensor el ement usi ng
ZnO and WO
3
mat erial are ongoing.
O OO OO Pre-commercial studies on adsorbed natural
gas technology (Gas Authority of India Ltd
(GAIL), New Delhi sponsored project)
This proj ect is execut ed as a collaborat ive proj ect wit h
INORGANIC & PHYSICAL CHEMISTRY INORGANIC & PHYSICAL CHEMISTRY INORGANIC & PHYSICAL CHEMISTRY INORGANIC & PHYSICAL CHEMISTRY INORGANIC & PHYSICAL CHEMISTRY
51
Coal, Gas and Energy Division of IICT. Charact erizat ion
of comp osi t e b l ocks f or p or e si ze d i st r i b ut i on and
surface area carried out in order t o check t he maximum
met h an e st o r ag e. Ad so r b en t co mp o si t e b l o cks
prepared by mast ering t he manufact ure procedure of
composi t e bl ocks t o t hei r appl i cat i on i n t he f i l ed of
n at u r al g as ad so r p t i o n ar e b ei n g car r i ed o u t .
Furt hermore charact eri zat i on of adsorbent i s carri ed
out t o evaluat e and correlat e t heir efficiency.
*BASIC RESEARCH
O Synt hesi s new dye mol ecul es f or Dye
Sensit ized Solar Cells (DSSC) applicat ions
(IICT- Ai si n Cosmos R&D Co., Lt d Japan Col l aborat i ve
Proj ect )
O OO OO Nanoparticles in Catalysis
Nanopart icles, very act ive cat alyst s are t o be st abilized
vi a i mmo b i l i zat i o n p r o cess i n o r d er t o p r even t
ag g l o mer at i o n d u r i n g cat al yt i c r eact i o n . In t h i s
d i r ect i o n , n an o p ar t i cl e i mmo b i l i zed cl ays an d
n an ozeol i t es w er ed evel op ed f or cat al yt i c or g an i c
t ransf ormat ions. These cat alyst s successfully displayed
superi or act i vi t y t o t he t une of 5-20 f ol d excess t han
t he cur r ent l y known cat al yst s i n t he al dol , Heck ,
Michael, nit roaldol, Wadswor t h-Emmons react ions and
synt hesi s of t et razol es.
O Solid Acid Cat alyst s
Mont mori l l oni t e and zeol i t es are versat i l e host s f or
var i ous Br nst ed and Lewi s aci d cat al yzed or gani c
t ransformat ions such as nit rat ion, acylat ion, alkylat ion,
sul f onyl at i on, et c. Mol ybdenum or t ungst en oxi de
mo d i f i ed zi r co n i a cat al yst s o b t ai n ed b y an
unconvent i onal met hod exhi bi t very st rong aci di t y
and int erest ing cat alyt ic act ivit y for t he facile synt hesis
of 1,1di acet at es from al dehydes under sol vent free
condit ions. The maj or advant age of Mo- or W- modified
zirconia, over sulfat ed cat alyst s, is t hat t he former does
not suffer from dopent loss during t hermal t reat ment s
and al so undergoes si gni f i cant l y l ess deact i vat i on
duri ng cat al yt i c runs. An ef f i ci ent synt hesi s of 1,5-
benzodi azepi ne deri vat i ves cat al yzed by t he sol i d
su p er - aci d su l f at ed zi r co n i a cat al yst w as al so
devel oped.
O Solid Base Cat alyst s
C-C bond format ion react ions are of prime import ance
f or f i ne chemi cal and bul k chemi cal synt hesi s. Sol i d
bases conceived, designed and synt hesised are found
t o b e ver y good cat al yst s i n C-C b ond f or mat i on
r eact i ons such as Al d ol , ni t r oal d ol , Knoevenag el ,
Mi chael , Wi t t i g-Hor ner, aza-Mi chael , ar yl at i on and
cyanosilylat ion of carbonyl compounds . These are t he
promising candidat es t o replace soluble bases, which
ar e co n t r i b u t i n g f o r t h e ef f l u en t g en er at i o n i n
enormous amount s.
O OO OO Asymmetric Catalysis
The wor k i nvol ves a desi gn and synt hesi s of new
complexes homogeneous as well as het erogenisat ion
vi a i mmob i l i sat i on of t he r esul t i ng comp l exes on
n at u r al an d syn t h et i c zeo l i t es, an i o n i c cl ays,
n an omat er i al s f or asymmet r i c cycl op r op an at i on ,
ep oxi d at i on, d i hyd r oxyl at i on and hyd r og enat i on
r eact i ons. Desi gn and devel op ment of i nnovat i ve
ani on exchange t echni que t o i mmobi l i se OsO
4
2-
on
h yd r o t al ci t e, r esi n , si l i ca su p p o r t s t o p er f o r m
asymmet ric hydroxylat ion successfully is t he landmark
in t he asymmet ric dihydroxylat ion area. The diols t hus
ob t ai n ed h ave w i d e sp ect r um of ap p l i cat i on s as
int ermediat es in drugs such as t axol and dilt iazem.
Transmission Electron Microscope (TEM)
Inorganic & Physical Chemistry
52
O Cat alysis in Ionic Liquids
Ioni c l i qui ds of f er t he opport uni t y of combi ni ng t he
advant ages of bot h homogeneous and het ero geneous
cat alysis in one syst em. That is t o say, immobilizat ion of
a cat alyst ( met al/ oxide/ complex) by support ing it in an
ionic liquid rat her t han on a surface may creat e highly
f ree, t hree-di mensi onal cent ers as i n a homogeneous
cat alyst but t he cat alyt ic react ion occurs at t he int erface
bet ween t he ionic liquid and t he react ant s in eit her t he
gas or i mmi sci bl e l i qui d phase. Appl i cat i on of i oni c
liquids in chemical processes has blossomed only wit hin
t he last decade. Met al complexes immobilized in ionic
l i qui ds are used i n Aza-Mi chael , sul f i mi dat i ons and
azi ri dnat i ons react i ons.
O Si l ver Cat al yst s i n Cont r ol l i ng Mi cr o-
or ganism in Water
Ag cat al yst s support ed on carbon and carbon coverd
alumina, prepared by elect rochemical deposit ion exhibit
superior act ivit y in cont rolling microorganism in wat er
co mp ar ed t o t h o se p r ep ar ed b y i mp r eg n at i o n
t echni que.
O Cat alyst s for Ammoxidat ion
A new t ype of cat alyst , based on het eropolyacid, was
d evel o p ed f o r o b t ai n i n g h i g h (mo r e t h an 90 %)
select ivit y t o t he nit rile. A novel met hod, called t he in
si t u syn t h esi s met h o d , w as d evel o p ed f o r t h e
p r ep ar at i on of ammon i um sal t of h et er op ol yaci d .
Car ri ed out ext ensi ve wor k on VPO cat al yst s f or t he
ammo xi d at i o n o f met hyl p yr azi n e. Th e st u d i y w as
ext ended t o ammoxidat ion of cresol using mixed met al
p h o sp h at e cat al yst s. Est ab l i sh ed t h e n o val
p o t en t i o met r i c t i t r at i o n t ech n i q u e f o r aci d i t y
det ermi nat i on.
O Catalytic Chlorination of Ethane
Development of a cat alyst syst em t hat could convert
et hane and chlorine int o vinylchloride, et hylene and
hydrogen chl ori de was t aken up. Af t er separat i on of
VCM, t he ot her t wo product s could be easily convert ed
again int o addit ional VCM by t he est ablished cat alyt ic
processes. This process is a bet t er opt ion compared t o
t h e al t er n at i ve p r o cess b ased o n et h an e
dehydrogenat ion which is highly energy int ensive and
o f f er s l o w er yi el d s. A l ab - scal e r eact o r f o r t h e
preliminary cat alyst evaluat ion was set up wit h on-line
analyt ical facilit ies. Several cat alyst s were prepared and
t heir preliminar y evaluat ion was carried out . The best
cat alyst was ident ified. St andardizat ion of t he react ion
condit ions t o obt ain opt imum yields of VCM, et hylene
and HCl . Reproduci bi l i t y st udi es were conduct ed on
cat alyst preparat ion.
O Pd based Cat alyst s for t he Hydrodechlori
nat ion of Chloroaromat ics & CFC-12
Pd based cat alyst for HDC react ion was synt hesized by
ad o p t i n g t h r ee d i f f er en t met h o d s n amel y
i mp r eg n at i o n , d ep o si t i o n p r eci p i t at i o n an d
mi cr owave h eat i n g. Th e sup p or t ed cat al yst s wer e
prepared by i mpregnat i ng t he commerci al support s
ZrO
2
, Al
2
O
3
, CeO
2
, Nb
2
O
5
, Si O
2
and CeO
2.
Two t ypes of
cat alyst s were evaluat ed for act ivit y st udies. (i) cat alyst
wit h high Pd cont ent (up t o 10 wt . % Pd) and (ii) cat alyst s
wit h low Pd cont ent (1 wt . % Pd). The HDC runs were
carried out on t hese cat alyst s. Cat alyst s prepared by
DP met h o d w i t h ch l o r i d e p r ecu r so r p r o vi d ed a
convenient approach for t he preparat ion of act ive and
st able cat alyst s wit h low Pd cont ent . The nat ure of t he
act i ve si t e w as eval u at ed af t er a t h o r o u g h
charact eri zat i on.
O Devel opment of Sol i d Cat al yst s f or
Biodiesel Synthesis
Th e exi st i n g cat al yst s f o r t h e est er i f i cat i o n an d
t r an sest er i f i cat i o n o f veg et ab l e o i l s f o r b i o d i esel
p r od uct i on ar e essent i al l y b ased i n homogeneous
cat al yst s o r mi n er al aci d s an d al kal i es. Si n ce t h e
processes based on t hese convent i onal cat al yst s are
53
not eco-friendly, at t ent ion was focused on development
o f so l i d cat al yst s. As a p ar t o f t h i s p r o g r amme
est erificat ion of palmit ic acid wit h met hanol was carried
out on vari ous sol i d cat al yst s l i ke zeol i t es, sol i d super
acids and het eropolyacids and t heir salt s.
O Novel nano-sized CeO
2
based mixed oxide
catalysts for three way catalysts (TWC) and
other applications
Novel nano-sized CeO
2
/ ZrO
2
and CeO
2
/ TiO
2
combinat ion
carri ers were prepared and charact eri zed by vari ous
physi cochemi cal t echni ques. The rel at i ve i nf l uence of
SiO
2
, TiO
2
and ZrO
2
on t he OSC propert ies CeO
2
was also
syst emat i cal l y i nvest i gat ed.
Microwave assist ed combust ion synt hesis of
nano-oxides
A nanocryst al l i ne t i t ani a-si l i ca (1:1 mol ar rat i o) bi nary
o xi d e w as syn t h esi zed b y mi cr o w ave i n d u ced
combust ion process in a modified domest ic microwave
oven (operat ed at 2.45 GHz frequency and 700 W power)
in ~60 minut es from i n si t u synt hesized t it anyl nit rat e
and siliconyl nit rat e using urea as fuel. For t he purpose
of comparison, t wo different t ypes of TiO
2
-SiO
2
powders
were also synt hesized by t he sol-gel and coprecipit at ion
met hods. The TEM in par t icular confirmed t he presence
o f n an o si zed p ar t i cl es i n t h e mi cr o w ave i n d u ced
comb ust i on synt hesi zed p owd er. Among t he t hr ee
an al o g i es, mi cr o w ave syn t h esi s w as f o u n d t o b e
superior in t erms of ease of processing leading t o t ime
and power savings.
O Cat alyst Design for one St ep Synt hesis of
2,6-Dimethylphenol
Novel V
2
O
5
/ In
2
O
3
-TiO
2
cat alyst syst em was designed and
t horoughly invest igat ed for t he met hylat ion of phenol
react ion .
O Aromatization of Isophorone to 3,5-xylenol
The role of acidic and basic sit es of t he cat alyst s were
st ud i ed i n t he ar omat i zat i on of i sop hor one t o 3,5-
xylenol by select ively blocking eit her acidic or basic sit es
by pumping NH
3
or CO
2
respect ively.
O NO
x
Abatement Catalysts
A syst emat i c i nvest i gat i on was undert aken t o make
t it ania-based mixed oxide support s for select ive cat alyt ic
reduct i on (SCR) and ot her appl i cat i ons. In t hi s st udy
various mixed oxide support s were designed and were
charact erized by different physicochemical t echniques.
O Defluoridation of Ground water
Adsorbent t echnol ogy i s adopt ed f or t he removal of
excess of f l uor i de i on i n gr ound wat er. Carb on and
al umi na based adsorbent s wi t h dopant s are st udi ed
for t his purpose and t he result s are quit e encouraging.
O Nonlinear Optics
Comput at i onal eval uat i on of nonl i near opt i cal (NLO)
propert ies of some Donor-Bridge-Accept or (D-B-A) t ype
of molecules have been carried out . The syst ems st udied
are eit her 3D molecules (or oct upolar), zwit t erionic and
nonzwit t erionic Push-Pull t ype of organic molecules. The
main focus of t his work was t o model efficient organic
mol ecul es wi t h ver y l ar ge NLO act i vi t y, ab sor p t i on
t ransparency t o t he vi si bl e regi on and vari ous ot her
spect roscopi c and charge t ransf er rel at ed propert i es.
Besi des t he t heoret i cal model i ng, some of t hese NLO
molecules are also synt hesized and t heir charact erist ic
proper t i es were al so est i mat ed experi ment al l y. These
r esu l t s sh o w t h e exi st en ce o f a g o o d co r r el at i o n
bet ween t he modeling and experiment .
O Molecular Electronics
Front i er Mol ecul ar Orbi t al (FMO) st udi es have been
applied t o analyze t he elect ron t ransport charact erist ics
of some D-B-A t ype of molecules. The st udies show t hat
t he el ect ron t ransf er and conduct ance propert i es of
t hese mol ecul es l argel y depend on t hei r di f f erent i al
bondi ng pat t erns and st ruct ural ori ent at i ons. In t hi s
Inorganic & Physical Chemistry
54
regard some pot ent ial molecular wires and molecular
rect ifier are suggest ed.
O Organic Light Emitting Diode
The main int erest lies in modeling of suit able organic
mo l ecu l ar mat er i al s, w h i ch p r o b ab l y can f i n d
applicat ions in elect ro luminescent (EL) layer of organic
l i g h t emi t t i n g d evi ces (OLED). In t h i s r eg ar d o u r
model i ng st udi es suggest some ? and ? subst i t ut ed
ant hracene derivat ives as act ive EL mat erials.
O Transient Molecules
Theoret i cal as wel l as mass spect ral anal ysi s of some
elusive molecules, which have lifet ime in pico second
r an g e h ave b een u n d er t aken . Th ese st u d i es h ave
si gni f i cant i mport ance i n t he f i el d mappi ng organi c
react ion mechanism (i.e., possible finding t he nat ure of
var i o u s i n t er med i at es an d t r an si t i o n s st at es),
i nt erst el l ar and ci rcumst el l ar react i ons (t hese st udi es
can give some clue in finding new st ellar ent it ies).
O Functional Dyes
The st udi es are di rect ed i n t he i nvest i gat i ons of new
funct ional dyes, which can find applicat ions in various
fields like solar cell and various opt ical devices.
O Binary Clusters
St udi es on Au-Cu cl ust er s ar e car r i ed out b y usi ng
var i o u s co mp u t at i o n al t ech n i q u es f o r smal l
clust ers[clust ers wit h fixed size of n=6 while varying t he
composit ion of t he clust er from pure Cu (Cu
6
) t o pure
Au (Au
6
) t h r o u g h Au
x
Cu
6-x
(x= 1- 5)] an d t h e
o b ser vat i o n s ext r ap o l at ed t o l ar g er cl u st er s t o
underst and t he ef f ect of t he shape of t he cl ust er on
co mmo n p r o p er t i es l i ke d i p o l e mo men t an d
absorpt ions which give us a fair underst anding of t he
nat ur of cryst al l i zat i on i nt o such mat ri xes as not onl y
energy but also dipoles which play an import ant part
i n cryst al l i zat i on.
O Separation of Hf from Zr Tailings
Wit h t he general view of underst anding t he int eract ions
of Zr and Hf met al compl exes wi t h t he sol vent s and
wi t h t he more speci fi c ai m of devel opi ng an effi ci ent
ext ract ant , t heoret i cal st udy was done. Our ai m i s t o
get t he quant it at ive pict ure of t he int eract ion energies
(pri mary i nt eract i ons), whi ch wi l l gi ve an i nsi ght i nt o
t he nat ure of Zr/ Hf int eract ing wit h TBP/ MIBK. Here t he
mai n g o al i s t o u n d er st an d t h e mo l ecu l ar l evel
i nt eract i ons (gas phase) of Zr and Hf compl exes wi t h
P= O g r o u p an d t h e C= O g r o u p s, an d w h at
conf ormat i ons do t hese comp l exes adop t wi t h t he
ligands. For t his we define some energy t erms, which
should help t o underst and which met al complex (Hf or
Zr) has more preference in t he solvent and what would
be t he gain or loss in energy when it passes from t he
aqueous medi a t o t he organi c phase. St udi es were
carried out using t he ab init io/ DFT soft ware, Gaussian
98(G98) whi ch i s based on t he Gaussi an orbi t al s and
al so usi ng Amst er dam Densi t y Funct i onal p ackage
(ADF) which is based on t he Slat er t ype orbit als.
O Bandgap engineering: Doping t it ania wit h anions
l i ke C, S, N ext ends t he ab sor p t i on i nt o t he vi si b l e
spect rum. This shif t is accompanied by a concomit ant
narrowing of t he band gap.
O Phot ocat alysis Ag-TiO
2
: Using TiO
2
nanopart icles
as t he phot ocat alyst , reduct ion of silver nit rat e t o silver
met al was done t o make a new met al -met al oxi de
nanocomposi t e.
O Nanost ruct ured morphol ogy by t empl at i ng:
Synt hesi s of nanost ruct ured -FeOOH and t hereby a-
Fe
2
O
3
wit h different archit ect ures by a simple process
by cont rol l i ng t he synt hesi s paramet ers.
55
The Li p i d Sci ence & Technol ogy Di vi si on has b een
t ransf ormed i nt o more i ndust ry-f ri endl y duri ng t hi s
p er i o d. Th e Di vi si o n h as r ef o cu sed i t s R & D i n
upgradat i on of t radi t i onal processi ng met hods and
n ew t ech n o l o g i es f o r d o w n st r eam p r o d u ct s o f
commercial import ance using modern approaches like
biot echnology and membranes. The Division ushered
l i p i d b i o t ech r evo l u t i o n d u r i n g t h i s p er i o d b y
developing enzymat ic degumming t echnology for rice
bran oil.
* ENZYMATIC DEGUMMING OF RICE BRAN
OIL
Ri ce bran i s a val uabl e co-product of t he ri ce mi l l i ng
i n d u st r y an d i t s o i l co n t en t r an g es f r o m 12- 25%
dependi ng upon t he qual i t y of t he bran. Chemi cal
r ef i ni ng of r i ce b r an oi l g ener al l y r esul t s i n l osses
consi derabl y hi gher t han t hose encount ered i n ot her
veget abl e oi l s due t o t he presence of l arger amount s
of free fat t y acids and non-t riacylglycerol const it uent s.
Refi ni ng l osses can be consi derabl y reduced by usi ng
physi cal ref i ni ng. For successf ul i mpl ement at i on of
physi cal ref i ni ng, t he most i mport ant pre-requi si t e i s
t h e ef f i ci en t r emo val o f g u ms. Man y In d i an o i l -
p r o cessi n g u n i t s h ave ad o p t ed p h ysi cal r ef i n i n g
w i t h o u t t aki n g measu r es t o l o w er t h e co n t en t o f
phosphorus. This is result ing in producing dark colored
oi l s, whi ch f et ch l ess val ue i n t he market . Enzymat i c
p r ocess i s t he answ er f or t he ent i r e p r ob l em as i t
cat al yzes t h e co n ver si o n o f n o n - h yd r at ab l e
phosphol i pi ds i nt o wat er-sol ubl e l yso-phosphol i pi ds,
whi ch are t hen removed by cent ri f ugat i on, yi el di ng
degummed oi l wi t h l ower phosphorus. Duri ng t hi s
p er i o d IICT came o u t w i t h an ef f i ci en t en zymat i c
degumming t echnology for rice bran oil (pat ent filed)
empl oyi ng a commerci al l y avai l abl e enzyme t o bri ng
down t he resi dual phosphorus l evel s t o 0 t o 5 ppm
af t er bl eachi ng and dewaxi ng. Thi s oi l , i f ref i ned i n a
well-maint ained physical refining unit , will produce good
qualit y edible rice bran oil. The enzymat ic degumming
process i s l ess energy i nt ensi ve, mi ni mi zes t he l oss of
o i l , an d r ed u ces w at er co n su mp t i o n an d mo r e
envi ronment al fri endl y.
This is one of t he out st anding proj ect s of IICT in t erms
of i t s reach and i mpact on t he Indi an Veget abl e Oi l
Indust r y. During t he last t hree years IICT has t ransferred
t his process t o about 14 rice bran refineries and 8 Proj ect
Engi neeri ng Comp ani es (as l i censee) sp read over 9
st at es f or i mpl ement at i on of enzymat i c degummi ng
t echnol ogy. Execut i on of t he proj ect at anot her f our
indust ries is in advanced st age. The Technology Mission
on Oilseeds, Pulses and Maize ( TMOP & M) came for ward
t o ext end a grant -in-aid assist ance of Rs.75 lakhs each
t o 15 indust ries (out of t he above 19) for est ablishing
50 t p d r i ce b r an o i l r ef i n er y b y emp l o yi n g IICTs
degummi ng process.
* ECO- FRI ENDLY SYNTHETI C AVI ATI ON
LUBRICANTS
En vi r o n men t al co n si d er at i o n s an d d w i n d l i n g
pet roleum reserves are likely t o see t he emergence of
LIPID SCIENCE & TECHNOLOGY LIPID SCIENCE & TECHNOLOGY LIPID SCIENCE & TECHNOLOGY LIPID SCIENCE & TECHNOLOGY LIPID SCIENCE & TECHNOLOGY
Degumming Commercial Unit from Industry Synthetic Aviation Lubricant (SAL) experimental unit
56
ol eochemi cal s as vi ab l e al t er nat i ve f eed st ocks f or
syn t h et i c l u b r i can t s. IICT h as i n i t i at ed sever al
programmes i n t hi s di rect i on and one such proj ect i s
t he devel opment of synt het i c avi at i on l ubri cant s. A
consort ium of six leading Indian Inst it ut es wit h IICT as
t he nodal agency was f ormul at ed wi t h a p rop osed
p r oj ect cost of over Rs.17 cr or es f or execut i ng t hi s
proj ect . The proj ect i s sponsored by Cent re f or Hi gh
Technology (CHT), Minist ry of Pet roleum & Nat ural Gas,
Govt . of India t o t he ext ent of Rs.8.4 crores. CSIR, DRDO
and part icipat ing organizat ions share rest of t he proj ect
cost . The proj ect was init iat ed in December 2002. The
rol e of IICT i n t he proj ect i s t o devel op a pi l ot scal e
process f or t he preparat i on of SVS 1 and SVS 2 base
st ocks f or syn t h et i c avi at i on l u b r i can t s. Ph ysi co-
chemical propert ies like TAN, Viscosit y, Pour point , Flash
point et c., are t he inherent propert ies of t he base st ock.
So p h i st i cat ed an al yt i cal t est i n g eq u i p men t s t o
det er mi ne Vi scosi t y (at l ow and hi gh t emperat ures),
Pour poi nt , Fl ash poi nt , Foam Tendency, Evaporat i on
loss, Corrosiveness and Oxidat ion st abilit y. During t his
period, laborat ory scale experiment s were carried out
f or t he synt hesi s of b ase st ocks w i t h t he r eq ui r ed
sp eci f i cat i ons. A 5 kg/ b at ch est er i f i cat i on r eact i on
syst em h as b een d esi g n ed , f ab r i cat ed an d
commissioned t o collect dat a for t he design of t he pilot
plant .
* BIODIESEL
Bi o d i esel i s an eco - f r i en d l y f u el o r i g i n at i n g f r o m
renewabl e source. It can part l y or t ot al l y repl ace t he
pet rol eum based di esel . Present l y bi odi esel i s bei ng
used by several count ri es l i ke Germany, Aust ri a, USA,
Canada, France. In order t o hast en t he biodiesel usage,
t he Pl anni ng Commi ssi on of Indi a has recommended
launching of Nat ional Mission t o init iat e t he plant at ion
of oilseed crops like Jat ropha and Karanj a followed by
gradual i nt roduct i on of bi odi esel bl endi ng i n di esel
upt o 20% by 2011. IICT was act ively part icipat ed in t he
p r ep ar at i o n o f Bi o d i esel Rep o r t o f Pl an n i n g
Commission and also helping AP St at e Government by
p ar t i ci p at i n g i n i t s Task Fo r ce f o r med f o r t h e
i mpl ement at i on of bi odi esel programme i n t he st at e.
TMOP&M has provi ded a f undi ng of Rs. 40 l akhs f or
execut i ng a proj ect on Devel opment of pi l ot scal e
process for biodiesel from high FFA oils and acid oils
during 2004-06. Work was init iat ed on t wo st ep cat alyt ic
p r ocess usi ng aci d i c cat al yst f or est er i f i cat i on and
t ransest erificat ion of glycerides in t he Jat ropha oil at 5
and 50 kg oi l per bat ch. Work has been i mi t at ed on
ot her cat alyst s such as biocat alyst s (lipases) and solid
ch emi cal cat al yst s. Bo t h est er i f i cat i o n an d
t ransest erificat ion met hodologies are being opt imized
using all t he pot ent ial oil sources like Karanj a. Work
h as al so b een i n i t i at ed f or t h e d evel op men t of a
cont i nuous process f or handl i ng mul t i -f eed st ock. A
proj ect proposal ent it led St udies on Physico-Chemical
Propert i es of Jat ropha Seeds and Cont i nuous Process
Devel opment f or t he Preparat i on of Bi odi esel was
submit t ed t o AP St at e Government for financial grant .
IICT is also looking at developing pot ent ial applicat ions
of by-product s such as unsaponifiable mat t er, oilseed
cake, gl yceri ne et c., The sci ent i st s of IICT del i vered a
numb er of i nvi t ed l ect ur es at di f f er ent wor kshop s,
conf erences, brai n st ormi ng meet i ngs t o st rengt hen
t he biodiesel movement in t he count r y.
* VALUE- ADDED PRODUCTS FROM
VEGETABLE OILS AND BY-PRODUCTS OF
PROCESSING INDUSTRIES
' Rice bran wax: Rice bran wax (3 t o 6% of crude
oil) is a by-product obt ained during dewaxing
process. A si mpl e and ef f i ci ent bench-scal e
Biodisel experimental unit
57
process (pat ent f i l ed) was devel oped f or t he
upgradat i on and bl eachi ng of crude ri ce bran
wax. The upgr aded wax may subst i t ut e t he
i mpor t ed carnauba wax f ul l y or par t i al l y. The
p r o cess h as b een d emo n st r at ed t o f o u r
i ndust ri es. One Proj ect Engi neeri ng Company
has t aken license for t his proj ect .
' Hydrogenat ed rice bran wax: A Process for t he
hyd r ogenat ed wax was al so d evel op ed and
t ransferred t o one i ndust r y.
' Triacont anol / polycosanol: Triacont anol and
pol ycosanol are present l y bei ng market ed as
p l an t g r o w t h st i mu l an t an d ch o l est er o l
reducing agent respect ively. IICT has developed
a bench-scale pat ent ed process for t he recovery
of t hese t wo product s from crude rice bran wax
and t ransferred t he process t o t hree indust ries.
' Oyrzanol: The soap-st ock generat ed dur i ng
alkali refining is a good source for g-oryzanol, a
bi ol ogi cal l y act i ve component used i n f oods
an d p h ar maceu t i cal s. A p r o cess w as
st an d ar d i zed o n l ab o r at o r y scal e f o r t h e
i sol at i on of oryzanol i n about 70% yi el ds wi t h
about 65-95% puri t y (Two Pat ent s grant ed).
' Leci t hi n and Lysol eci t hi n: Leci t h i n an d
l ysol eci t hi n are t he by-product s of wat er and
enzymat i c degummi ng processes of ri ce bran
oil. These product s have lot of pot ent ial in food
and pharmaceut icals applicat ions. A laborat ory
scal e-process was devel oped f or bl eachi ng of
t hese p r od uct s and t he p r od uct s ar e b ei ng
ch ar act er i zed an d eval u at ed f o r n ew er
applicat ions using a financial grant of TMOP&M
i n col l ab or at i on wi t h Pr oj ect Di r ect or at e on
Poult r y, ICAR, Hyderabad
' Phyt ic acid and Inosit ol: Phyt ic acid is present
t o t he ext ent of 3-10 in rice bran and is endowed
wit h at t ract ive biological propert ies. A bench-
scale process was successfully developed for t he
ext ract ion of phyt ic acid from deoiled rice bran.
A l aborat ory scal e process was al so opt i mi zed
f or t he preparat i on myo-i nosi t ol f rom phyt i c
acid (TMOP&M sponsored proj ect )
' Preparation of novel phospholipids from soya
lecit hin: Duri ng t he execut i on of t hi s proj ect ,
main t hrust was given t o add value t o soybean
oil gums as t here is lot of scope for t he Indian
soybean oil indust ry t o exploit soya lecit hin for
t heir economic growt h by preparing food grade
and modified lecit hins for various applicat ions.
React i on condi t i ons wer e op t i mi zed f or t he
p r ep ar at i on of var i ous p r od uct s f r om soya
l eci t h i n n amel y No n - h yd r o g en at ed so l i d
l eci t hi n, Hydroxl at ed l eci t hi n, Epoxy l eci t hi n,
Lyso l eci t h i n , an d Devel o p men t o f ch emo -
en zymat i c met h o d f o r t h e p r ep ar at i o n o f
phosphat i dyl chol i ne wi t h desi red f at t y aci ds
(DBT sponsored proj ect )
' Synt hesis and evaluat ion of reduced calorie
fat s: Reduced calorie fat s are not being prepared
i n o u r co u n t r y an d t h er e i s n o i n d i g en o u s
t echnology available for t he preparat ion of such
t ype of compounds. A novel st ruct ured fat was
syn t h esi zed en zymat i cal l y w i t h i mp r o ved
nut ri t i on and reduced cal ori fi c val ue (5.3 kcal /
mole) from easily available renewable sources.
Th e r ed u ced - cal o r i e p l ast i c f at h as t h e
co n si st en cy o f van asp at i w i t h o u t an y
del et er i ous t rans f at t y aci ds. The presence of
essent i al f at t y aci ds and nat ural ant i oxi dant s
makes t he reduced cal ori e f at superi or t o t he
o t h er r ed u ced cal o r i e f at s avai l ab l e i n t h e
int ernat ional market . This is complet ely a new
area of research in our count r y. The upscaling
st udies of some select ed novel reduced calorie
f at s ar e i n p r ogr ess wi t h t he f i nanci al gr ant
received from DBT.
' Synt hesis of alkyl ricinoleat es and 12-hydrocy
st earat es: A si mp l e enzymat i c met hod was
Lipid Science & Technology
58
developed for t he preparat ion of cosmet ic base
mat erials like alkyl ricinoleat es and 12-hydroxy
st earat es wit hout format ion of est olides. These
co mp o u n d s w er e su l p h at ed an d f o u n d t o
exhibit good surfact ant propert ies.
' Preparat ion of ricinoleic acid and 12-hydroxy
st earic acid est olides and evaluat ion of t heir
sodi um and sul f at ed sodi um sal t s f or
surfact ant propert ies: Est ol i des exhi bi t hi gh
vi scosi t y i ndi ces, good oxi dat i ve st abi l i t y and
are bi odegradabl e. These compounds have a
var i et y o f p o t en t i al ap p l i cat i o n s as b ase
mat eri al s i n l ubri cant s, greases, pl ast i cs, i nks,
cosmet ics, and surfact ant s. In t he present st udy
ricinoleic and 12-hydroxy st earic acid est olides
were prepared wit h varying molecular weight s
and evaluat ed for t heir surfact ant propert ies as
t heir sodium salt s and sulfat ed sodium salt s. The
sul f at ed sodi um sl at s of monomer, di mer and
t rimer exhibit ed superior surfact ant s propert ies
compared t o t heir corresponding sodium salt s
' Enzymat i c f at spl i t t i ng: En zymat i c f at
hydrolysis is a very mild process and has many
advant ages over t he convent ional fat split t ing.
A l aborat ory scal e met hod was devel oped f or
t he enzymat i c fat spl i t t i ng usi ng soybean and
r i ce b r an o i l s an d al so f o r h ar d f at s l i ke
hydrogenat ed cast or oi l , sal and mango f at s
usi ng t hermost abl e l i pases. Furt her work i s i n
progress t o upscale t he process (Sponosred by
Direct orat e of Vanaspat i, Veget able Oils & Fat s)
' Sebaci c Aci d: Seb aci c aci d i s u sed i n t h e
man u f act u r e o f co mmer ci al l y i mp o r t an t
p l ast i ci zer s and l ub r i cant s. The p rocess has
been opt imized in cont inuous mode (0.5 kg/ hr)
using t he funding of TIFAC (DST).
' Miscellaneous projects: During t his period Lipid
Sci ence & Technol ogy Di vi si on has i ni t i at ed
w o r k i n var i et y o f sp eci f i c ar eas l i ke
Devel o p men t o f Sp eci al t y f at l i q u o r s
(Sp on osr ed b y Bal mer Law r i e Lt d ., Leat h er
Chemi cal s Di vi si on, Chennai ), Eval uat i on of
Bb end ed ed i b l e oi l s cont ai ni ng EPA & DHA
(Sp o n so r ed b y M/ s Reco n Oi l In d u st r i es,
Mumbai ), Recombi nant approach t o produce
-l i n ol en i c aci d an d d ocosah exaen oi c aci d
(DHA) in Sunflower and Yeast (NMITLI proj ect ,
Avest hagen Lt d., Bangal or e as an i ndust r i al
part ner), Explorat ive st udies on eripupae and
er i p r e-p up ae Oi l (Sp onsor ed b y Cent r al Si l k
Board, Bangal ore)
' Value-added product s from glycerol pit ch:
Glycerol pit ch is a by-product of fat split t ing and
t he indust ry is st ruggling t o even dispose t his
mat er i al . Wo r k w as i n i t i at ed t o p u r i f y an d
prepare variet y of est ers wit h good surfact ant s
p r o p er t i es (Sp o n o sr ed b y Di r ect o r at e o f
Vanaspat i, Veget able Oils & Fat s).
* TASK FORCE PROJECTS
The Li p i d Sci ence and Technol og y Di vi si on i s al so
par t icipat ing in t he following from Task Proj ect s of CSIR
f or t he devel opment of new generat i on l ubri cant s,
nut raceut icals and enzymat ic ext ract ion of oil from rice
bran.
Task Force on Technologies for Organic Chemicals
Enzymat ic Ext ract ion of Rice Bran Oil (IICT & RRL-T)
Gamma Linolenic acid from agro product s (RRL-
J, RRL-T & IICT)
Pi l o t scal e p r o cess f o r t h e i so l at i o n o f
p hyt ost er ol s f r om veget ab l e oi l d eod or i zer
dist illat e (RRL-J, IICT)
Task Force on New Generat ion Fuels and Lubricant s
(Nodal Agency IIP)
Development of Biodegradable lubricant s from
veget able oils (IICT, IIP)
Task Force on Nat ure and nat ure-l i ke bi o-act i ve
molecules (Nodal Agency-CFTRI)
59
Pot ent ial synt hesis of oryzanol (IICT, CFTRI)
Task Fo r ce o n Po si t i o n i n g Nu t r aceu t i cal s an d
nut ragenomics in global plat form (Nodal Agency:
CFTRI)
Devel opment of scal e-up of l aborat ory scal e
p r o cess f o r t h e p r o d u ct i o n o f l eci t h i n an d
glycolipids (IICT, CFTRI)
Enzymat ic modificat ion of specific oils and fat s
f or t ai l or made nut ri t i onal and f unct i onal f at s
(IICT, CFTRI)
* MEMBRANE SEPARATIONS
Membrane Separat i on sci ences i s one of t he newer
separat i on t echni ques used i n t he i ndust ri es. Though
t he use of t hi s t echni que i n aqueous syst em i s wel l
known, informat ion regarding it s uses in non-aqueous
syst em is t oo sparse and t here exist t remendous scopes
for developing some uses for non-aqueous syst em like
i n veg et ab l e o i l . IICT h as i n i t i at ed a p r o j ect i n
col l ab or at i on wi t h CGCRI wi t h a f i nanci al g r ant of
TMOP&M on Development of t echnology package for
cer ami c memb r an e mo d u l e f o r u l t r af i l t r at i o n o f
veget able oils for physical refining. In t his proj ect , CGCRI
has t o develop t he UF ceramic membranes and IICT has
t o eval uat e t hei r perf ormance f or degummi ng of ri ce
bran and soybean oils and work is in progress.
IICT has developed a process for recycling/ reuse of t he
wast ewat er coming out of a physical refining unit of a
veget abl e oi l ref i nery and present l y IICT i s t ryi ng t o
upscal e t he process. It has al so devel oped a si mi l ar
process for Dair y wast ewat er also. The wat er quant it y
obt ained aft er t he membrane t reat ment was found t o
be very good and t hat can be recycl ed back t o t he
process.
* BASIC RESEARCH
Lipid Science & Technology Division has t aken up many
init iat ives t o spread t heir research base int o variet ies of
ar eas l i ke l ow cal or i e f at s, i n f an t mi l k sub st i t ut es,
st ruct ured fat s for novel applicat ions, oleochmical-based
lubricant s, sur fact ant s, cosmet ics and per fumery, novel
met hodol ogi es f or deri vat i zat i on of unsat urat i on and
carboxylic group of fat t y acids, leat her chemicals, animal
f at s f o r p o ssi b l e ap p l i cat i o n s i n i n d u st r i al an d
nut raceut i cal sect ors.
O Development of New Lipid based Delivery
Syst ems for Bio-act ives
A ser i es of n ovel cat i on i c amp h i p h i l es h ave b een
designed & synt hesized and t he gene t ransfer propert ies
of t hese new generat ion of cat ionic t ransfect ion lipids
have been eval uat ed. Our resul t s have enri ched t he
field of liposomal gene deliver y. (DBT-funded proj ect ).
Six novel cat ionic t ransfect ion lipids have been designed
& synt hesized and sent t o Dabur for evaluat ion of t heir
gene t ransf er propert i es (Dabur Research Foundat i on
(DRF) sp o n so r ed p r o j ect ). A ser i es o f n o vel
hist idinylat ed cat ionic amphiphiles have been designed
an d syn t h esi zed . St u d i es ai med at exp l o r i n g t h e
p o t en t i al o f t h ese n o vel cat i o n i c l i p i d s i n DNA
vacci nat i on are i n progress (DBT sponsored proj ect ).
Bulk preparat ion of t wo of our most in vivo promising
cat ionic t ransfect ion lipids have been complet ed aimed
at exp l or i ng t hei r p ot ent i al use i n heal i ng chr oni c
wounds (IICT-Virchow Biot ech-DST proj ect ). The init ial
in vit ro experiment s using cult ured animal cells t owards
exp l o r i n g t h e p o t en t i al o f o u r n o vel RGD-l i p i d i n
t arget ing t umor vasculat ures have been complet ed. A
number of publicat ions in high impact fact ors j ournals
and overseas pat ent s have result ed from t his import ant
research carried out bot h independent ly by IICT and in
collaborat ive research wit h CCMB, Hyderabad and CNRS,
France.
Lipid Science & Technology
60
* APPLIED RESEARCH
O Devel opment of speci al gr ade epoxy
novolac system suitable for canister ( PJ-10)
appl i cat i on, Def ense Resear ch and
Devel opment Labor at or y (DRDL),
Hyderabad
Filament winding is an import ant fabricat ion t echnique
f or maki ng l arge comp osi t e st ruct ural p art s. Ep oxy
resins are being widely used for t his purpose because
of good mechanical and ret ent ion of propert ies under
severe oper at i ng condi t i ons. Thi s t echnol ogy i s not
avai l ab l e t o In d i a d u e t o st r at eg i c r easo n s. The
d evel o p men t o f t h i s t ech n o l o g y i s cr i t i cal t o o u r
su p er so n i c mi ssi l e t ech n o l o g y f o r l au n ch i n g t h e
mi ssi l es f r o m su b mar i n es. IICT h as i d en t i f i ed t h e
const it uent s of t he resin syst em of Russian origin and
devel oped a resi n syst em sui t abl e for manufact ure of
p rep regs meet i ng t he sp eci f i cat i ons of t he Russi an
made samples. Technical repor t has been submit t ed t o
sponsor on complet ion of t he proj ect .
O Low loss polyester resin for aircraft radomes
Radome, a t hi n cover prot ect i ng radar, i s a funct i onal
comp osi t e st r uct ur e mad e up of r ei nf or ci ng f i b er s
embedded in a resin mat rix. IICT has developed a resin
syst em u sef u l f o r t h e f ab r i cat i o n o f Rad o me. The
p er f o r man ce o f r ad ar d ep en d s o n t h e q u al i t y o f
radome, which t ransmit s t he signals back and fort h for
ident ifying t he t arget s. The resin syst em has passed all
t h e t est p ar amet er s an d t h e p r o cess h as b een
approved by ADA af t er st ri ngent t est i ng procedure.
The resin was produced in our pilot plant s and supplied
t o sp onsor s, ADA, Bangal or e (500Kg) and t o HAL,
Bangal ore (350Kg).
O Synt hesi s and Devel opment of new
Biodegradable and Biocompat ible poly
mers for Tissue Contacting Applications
Wor k has b een comp l et ed successf ul l y and r ep or t
sub mi t t ed t o sp onsor Dep ar t ment of Sci ence and
Technology, DST, New Delhi
O Synt hesis and Development of Cyanat e
Est er Based Resins for Advanced Aircraft
Applications
Wor k has b een comp l et ed successf ul l y and r ep or t
submi t t ed t o sponsor ADA, Bangal ore
O Development of Solder resistant Cfoating
This coat ing formulat ion has been developed which is
a dual curing syst em ie., t hermal as well as UV curing
and report submit t ed t o an overseas client .
ORGANIC COATINGS AND POLYMERS ORGANIC COATINGS AND POLYMERS ORGANIC COATINGS AND POLYMERS ORGANIC COATINGS AND POLYMERS ORGANIC COATINGS AND POLYMERS
Polymer developed in IICT used in the radome of
Light Combat Aircraft (LCA)
61
O Development of Polymeric Materials for PU
coatings
Two polyols based on cast or and linseed oils developed
b y IICT have shown g ood p r op er t i es comp ar ed t o
i mp or t ed samp l es. Th e p r o d u ct s ar e r ead y f o r
commercial exploit at ion.
O Development of Polymeric Binder for t he
preparat ion of composit es from t annery
waste
A pol ymeri c emul si on was devel oped t o be used as
binder for t he preparat ion of composit es using wast e
mat er i al f r om ani mal ski ns. These comp osi t es have
shown promi si ng resul t s. Process may be rel eased t o
i nt erest ed part i es on sponsorshi p basi s.
O Devel opment of Rai n Erosi on resi st ant
Coating
A series of segment ed polyuret hane resins have been
prepared and formulat e a rain erosion resist ant coat ing,
which has shown promising result s. Furt her work is in
progress. Some of t he panels have passed 180 mt s. of
rain erosion t est at 1 mm rain drop size and 1800 RPM
as per MIL specificat ion.
* BASIC RESEARCH
' Biomaterials
Pol ymer adhesi ves and seal ant s have been used f or
several years in medical pract ice for j oining and sealing
t i ssues. Duri ng surgeri es or i nj ury a surgeon needs t o
arrest fluid leaks in a pat ient and sut ures or st aples are
rout i nel y used t o cont rol such fl ui d l eaks. But several
i nt er nal or gans ar e ei t her t oo del i cat e or smal l f or
surgeons t o use met hods ef f ect i vel y wi t hout causi ng
ad d i t i o n al t r au ma. Devel o p men t o f b i o l o g i cal l y
accep t ab l e seal an t s co u l d i mp r o ve a su r g eo n s
efficiency eit her by complet ely replacing sut ures or by
augment ing t hem. In t his work a series of hydrophobic
ally graded, in sit u polymerizable liquid sealant s were
prepared and invest igat ed for sealant and drug delivery
applicat ions. They were also found t o be bio compat ible
upon subcut aneous implant at ions in Swiss albino rat s.
' Fiber reinforced composites
Fiber reinforced composit es made wit h synt het ic resins
ar e w i d el y u sed i n au t o mo b i l e an d aer o n au t i cal
i ndust ri es f or t hei r advant ageous st rengt h t o wei ght
rat i o. For el evat ed t emperat ure servi ce appl i cat i ons,
hi gh T
g
t hermo set resi ns are normal l y used. Cyanat e
est er r esi n s h ave r ecen t l y at t r act ed at t en t i o n o f
composi t e f abri cat ors wi t h t hei r hi gh T
g
and rel at i ve
easy, epoxy like processing. Like any ot her highly cross
linked t hermoset t ing resin, cyanat e est ers also t end t o
be brit t le and need t o be modified suit ably t o be able
t o serve mechanical or st ruct ural funct ions. In t his work
effort s have been made t o improve t he basic propert ies
of cyanat e est er b ased comp osi t es usi ng r eact i ve
b l en d i n g an d t h er mo p l ast i c mo d i f i cat i o n w i t h
pol ysul f one.
Organic Coatings and Polymers
62
* Direct Sourcing of Coal for Value-added
Chemicals:
Coal i s predomi nant l y aromat i c, coal mat ri x cont ai ns
basic aromat ic building blocks wit h 2-6 condensed rings,
which ot herwise are not available in any ot her nat ural
source i ncl udi ng pet rol eum. These aromat i cs fi nd use
in indust ry - or engineering plast ics e.g. fibers, aromat ic
pol yami des and l i qui d cr yst al l i ne pol ymers (LCP). The
met hodology of t his proj ect is t o select ively obt ain t he
ar o mat i cs an d p h en o l s b y cat al yt i c cl eavag e o f
met hylene and et her bridges int erspersed bet ween t he
polycyclic aromat ic rings. The residual coal fuel value is
al so enhanced by t appi ng t hese compounds. Resul t s
of exp er i ment s w i t h Co-W/ Al
2
O
3
and CO-Mo/ Al
2
O
3
cat alyst s, at react ion t emperat ures 150-375
0
C and <50
kg/ cm
2
p r essur es on cat al yt i c d eg r ad at i on of coal
showed t hat i) t he cat alyst s are effect ive t o cleave t he
met hyl ene bri dges i n coal , i i ) aromat i c ri ngs are not
hydrogenat ed, i i i ) t he al kyl groups on aromat i c ri ngs
are cleaved. iv) pressures in t he range 30-50 kg/ cm
2
are
n ecessar y f or i mp r oved yi el d s, v) i t i s p ossi b l e t o
enhance t he yield of low boiling aromat ics, part icularly
2- and 3-ri ng aromat i cs by choosi ng proper cat al yst s
and process condi t i ons.
(sponsored by Minist ry of Coal, Govt . of India)
* Hot Gas Clean-up:
This is a collaborat ive work bet ween IICT and t he Cent re
f or Energy Technol ogy (CET) of Osmani a Uni versi t y,
Hyderabad. The aim is product ion of clean fuel gas from
coal-derived gases using react ive, regenerable sorbent s
f or sul f ur removal and cerami c candl e f i l t ers f or f i ne
par t iculat es cont rol. The hot gas desulphurizat ion set up
made of Inconel-600 alloy designed t o operat e at 850
o
C,
20 bar pressure and 20 Nl pm f l ow was f ound t o be
durable during t he repeat ed heat ing/ cooling cycles. The
sorbent s sel ect ed f or t he st udi es on sul f ur removal
f rom coal gas mi xt ures i ncl ude 3 mm pel l et s of Zi nc
oxide (on Zeolit e) and Zinc ferrit e wit h high affinit y t o
sulphur while t hose wit h low affinit y t o sulphur include
Iron Ort ho-si l i cat e and Iron Chromi t e. Onl i ne anal ysi s
of di f f erent process gas st reams such as Feed, Cl ean
gas, sour gas is done by an on-line Gas Chromat ograph
wi t h ( TCD + FID + FPD) assembl y. Dust removal t ri al s
are complet ed and sulphur removal/ recovery t rials are
i n progress.
Trial runs of adding coal ash using a Dust y Gas Simulat or
i nt o t he hot ai r st ream at 20 bar pressure and 850
o
C
and subsequent removal of dust i n t he candl e f i l t ers
were successful l y compl et ed. Removal of t he dust by
dedust ing t he candle filt er surfaces by frequent back-
pul si ng wi t h hot ni t rogen (40 bar, 200
o
C) was carri ed
COAL, GAS AND ENERGY COAL, GAS AND ENERGY COAL, GAS AND ENERGY COAL, GAS AND ENERGY COAL, GAS AND ENERGY
Hot gas clean up unit for IGCC application
63
o u t an d d u st co l l ect ed i n t h e f i l t er vessel w as
successf ul l y recl ai med. Number of experi ment s usi ng
ai r were compl et ed. Experi ment s usi ng si mul at ed gas
mi xt ures coul d not be compl et ed as t he heat er coi l s
got snapped during t he experiment at ion. Collect ion of
p r ocess & anal yt i cal dat a on Desul p hur i sat i on i s i n
progress. One high-affinit y sorbent (ZnO) and one low-
affi ni t y sorbent (Fe
2
SiO
4
) were packed i n t he dual bed
ad sor b er s. Si mul at ed gas mi xt ur es cont ai ni ng CO
2
,
h yd r o g en , n i t r o g en an d COS w er e p r ep ar ed ,
compressed and st ored at 60 bar in t he st orage cylinder.
Gas at 20 Nlpm flow rat e and 20 bar pressure was heat ed
t o 850
o
C in t he gas heat er, passed t hrough t he adsorbers
at 850
o
C and out l et gas was anal ysed. 100% carbonyl
sul f i de removal was achi eved. Wor k i s i n progress f or
evaluat ion of dat a and preparat ion of Technical Repor t .
(Sponsored by Minist ry of Coal, Govt . of India).
* CO
2
Free Hydrogen (NMITLI)
Th e p r o j ect i s ai med at st u d y, eval u at i o n an d
development of carbon / Ni cat alyst s t o obt ain CO
2
free
h yd r o g en b y t h er mo cat al yt i c d eco mp o si t i o n o f
met hane. IICT prepared and evaluat ed cat alyst s of IICT
along wit h IIP and commercial Engelhard cat alyst s in
f l ui d i zed b ed r eact or. 10 hour s cat al yst l i f e wi t h a
met hane conversion of 140-40 mol/ gr 1/ S-1 is achieved
whi l e produci ng pure H
2
and C. The carbon deposi t s
mat ch ed w i t h met h an e co n ver si o n . Cat al yst
ch ar act er i zat i o n st u d i es ar e i n p r o g r ess t o sel ect
suit able cat alyst t o meet t he proj ect obj ect ives.
* Fuel Cell Power Pack (50 kW) with Methanol
as Primary Fuel
This proj ect is sponsored by Minist ry of Non-Convent io
nal Energy Sources (NMEs), New Delhi.
The exi st i ng 10 kW met hanol ref ormi ng syst em was
modi f i ed for bet t er heat t ransfer and more ef f i ci ency.
Aft er modificat ion, t he reforming unit was cont inuously
operat ed t ot ally about 500 hours for syst em endurance.
During operat ion design dat a was generat ed for scaling
up t he unit t o 50 kW level. The hydrogen rich gas was
p r od uced f r om t he met hanol r ef or mer cont ai ni ng
about 1% of CO. It has t o be reduced t o about 10 ppm
level t o suit for t he PEMFC applicat ion. Work has been
car r i ed out usi n g b ot h l ow t emp er at ur e sh i f t an d
preferent ial oxidat ion of CO. Based on t he result s it was
p rop osed t o i nt egrat e t he ref ormer wi t h t wo st age
PROX. The mechanical design of t he met hanol reformer,
gas cl ean up, equi pment , and heat t ransf er uni t and
ot her sub-syst ems has been complet ed. Specificat ions
were drawn f or al l t he i nst rument s. Order has been
placed for fabricat ion of t he 50 kW met hanol reforming
syst em. The uni t i s expect ed t o be del i vered shor t l y.
Work i s i n progress f or commi ssi oni ng and t est i ng of
t he 50 kW Met hanol Ref ormer and demonst rat i on of
t he reformer Fuel Cell int egrat ed unit .
Coal, Gas and Energy
64
Chemi cal and Inst rument Anal ysi s pl ays a pi vot al rol e
in R&D and manufact uring pract ices. It has developed
t r emen d o u sl y o ver t h e year s w i t h t h e h el p o f
sophi st i cat ed anal yt i cal i nst rument s. R&D f or NCEs,
nanot echnol ogy, bi ot echnol ogy, composi t e mat er i al s
and pol l ut i on cont rol coul d not have been possi bl e
w i t h out t h e l ever ag e of ch emi cal an d i n st r umen t
anal ysi s. It has i mmensel y cont r i b ut ed t o p r od uct
q u al i t y, co st con t r o l , mi n i mi zat i o n o f w ast e an d
envi ronment al regul at i ons.
Chemi cal & Inst rument Anal ysi s Di vi si on at IICT pl ays
an import ant role in providing analyt ical services in t he
process development act ivit ies in different areas of R&D.
The Division, in brief, provides t he following services:
1. Analyt ical support t o R&D proj ect s
2. Sup p or t s d i f f er en t g over n men t al ag en ci es
t hrough anal yt i cal servi ces
3. Gi ves q ual i t y assur ance and assessment of
i ndust ri al and consumer goods
4. Car r i es o u t b asi c an d ap p l i ed r esear ch i n
analyt ical chemist ry and
5. Sup p or t s human r esour ce d evel op ment b y
o r g an i zi n g t r ai n i n g co u r ses, semi n ar s,
workshops, et c.
Th e Di vi si on p r ovi d ed ser vi ce t o man y i n d ust r i es,
government agencies and consumers in assessing t he
qualit y of indust rial and consumer product s.
* APPLIED RESEARCH
O Synt hesis and charact erizat ion by EI, CI and ESI
Mass Sp ect r a o f t h e p r ecu r so r s f o r su l f u r
must ards, schedule compounds under CWC.
O Synt hesis and different iat ion of isomeric O, O-
d i al kyl N,N- d i al kyl p h o sp h o r ami d at e
compounds by EI mass spect roscopy.
O Ident ificat ion and fingerprint ing of aroma and
volat ile organic compounds in short grain and
Basmat i r i ce b y GC-MS. Th e maj o r ar o ma
comp oun d 2-acet yl p yr r ol i d i n e (2-AP) w as
quant i f i ed. Met hyl ni cot i nat e was al so f ound
and monit ored by GC-MS.
O Isoprot uron and chl oroyri phos pest i ci des as
Cert i f i ed Ref erence Mat eri al s were made and
rel eased. Cypermet hri n and Fenvel arat e are
under process for release.
O HPLC met hod f or r esi d ue d et er mi nat i on of
Azadiract in in t obacco leaves was developed.
O HPLC met hod f or f l avonoi d comp ound s i n
Pigeonpea (Caj anus caj an) was developed.
O An HPLC met hod was validat ed for Topiramat e.
O Impuri t y prof i l i ng and val i dat i on as per ICH
guidelines for Cyclosporin A
O HPLC met hod for lact ic acid and GPC met hod
for polymeric lact ic acid
O Charact eri zat i on of homo pol ymers/ copol y
mers of acrylic acid and acrylamide using GPC.
* BASIC RESEARCH
O Gas phase acidit ies for a series of dicarboxylic
acids were est imat ed
O Gas p h ase b asi ci t y val u es f o r g al act o se,
mannose and t al ose were measured f or t he
fi rst t i me
O A chemi cal i oni zat i on met hod f or mol ecul ar
w ei g h t i n f o r mat i o n o f ch l o r o p i cr i n (CP) a
kn o w n w ar f ar e ag en t an d i n sect i ci d e w as
devel oped
O Prot on affinit y values for fift y common mat rices
used in MALDI were det ermined.
O ESI mass spect ral st udies of lact ic acid and it s
met hyl est er in presence of CO
2+
, Ni
2+
, Cu
2+
and
Zn
2+
O Gas phase generat ion and charact erizat ion of
di-coordinat ed phosphorus species, [HS-P-OH],
S=P(OH)
2
CH
3
OPO
+
,CH
3
OPNH
2
+
, Sel enoket ene
(H
2
C=C=Se), Selenoket yl Cumulenes (HC=C=Se)
Sel en o cu mu l en e HC
3
Se,Met h yl en e
i sot hi ocyanat e [ CH
2
NCS] ,Neut ral prot onat ed
silanoic acid HSi(OH)
2
by NRMS was done.
O El ect r o sp r ay i o n i zat i o n t an d em mass
spect romet ry was used t o charact eri ze some
Boc prot ect ed non-nat ural amino acid pept ides
CHEMICAL & INSTRUMENT ANALYSIS CHEMICAL & INSTRUMENT ANALYSIS CHEMICAL & INSTRUMENT ANALYSIS CHEMICAL & INSTRUMENT ANALYSIS CHEMICAL & INSTRUMENT ANALYSIS
65
and t hei r gas p hase i nt er act i on wi t h al kal i
met al ions.
O Preparat i on, i sol at i on and charact eri zat i on of
minor impurit ies of Ast axant hin by HPLC
O Moni t ori ng phot odegradat i on pat hways wi t h
PDA, MS-MS det ect ors for St ilbene sulfonic acids
indust rial wast e wat ers using HPLC
O Sep ar at i o n an d d et er mi n at i n o f syn t h et i c
i mp u r i t i es i n Si l d en af i l , No r f l o xaci n an d
Difloxacin by HPLC
O Bi o d eg r ad at i o n an d b i so r p t i o n st u d i es o f
ar o mat i c su l f o n i c aci d s i n i n d u st r i al
wast ewat ers
O Enant iomeric purit y of chiral drugs by cellulose
and amyl ose b ased p hases usi ng PDA and
pol aromet ri c det ect ors
O Zeol i t e and met al i ncor p or at ed zeol i t es as
st at i onar y phases i n TLC f or cat al yt i c i n-si t u
synt hesis of complex molecules
O Ti ssu e cu l t u r e o f Ur g i n ea co n g est a an d
charact erizat ion of glycosidic component s
O Eval uat i on of Chl oroxyl on swi et eni a DC f or
insect icidal and larvicidal act ivit y
O Syn t h esi s an d At r o p i so mer i sm o f meso -
t et raki s(4-chl orocoumari n-3-yl )porphyri ns
O Ph ysi co ch emi cal p r o p er t i es l i ke act i vi t y
coefficient s, heat s of solut ion were det ermined
f o r co mmo n l y u sed o r g an i c so l ven t s o n
di mmer aci d met hyl and t ri t ol yl p hosp hat e
est ers
O Tr ace l evel i n or g an i c i mp ur i t y p r of i l i n g of
pharmaceut ical subst ances by ICP-MS
O Met hod validat ion for bulk drug and impurit ies
f o r In d i n avi r, Zud ovi d i n e, Lami vu d i n e an d
Gabapant in by Capillary Elect rophoresis
O St udi es on rai n wat er sol chemi st ry usi ng i on
chromat ography and el ect rophorosi s
O Heavy Met al Sp eci at i o n f o r mo n i t o r i n g
pol l ut i on i n t he cont ami nat ed areas around
Hyderabad
O Phyt of i l t rat i on f or t he removal of arseni c (III)
species from arsenic cont aminat ed wat ers
O St at ist ical and Mat hemat ical modeling t o assess
t he ext ent of pol l ut i on i n t he i ndust ri al areas
and t o predict t he movement of arsenic in t he
geological layers
O Ph yt o ext r act i o n f o r t h e r emed i at i o n o f
pest i ci des cont ami nat ed soi l s
O At mo sp h er i c ch emi st r y st u d i es i n n o r t h -
east ern Indi a
O Det ect i o n o f cel l u l ar ch an g es d u r i n g
different iat ion of PCC4 cells by curcumin.
O El ect r o sp r ay i o n i zat i o n , t an d em mass
spect romet ry and ion-molecule react ions were
u sed t o ch ar act er i ze t r an si t i o n met al
co mp l exes o f 2- acet yl b en zi mi d azo l e
t hi osemi carbazone.
O The ef f ect of spacer chai n l engt h on Li
+
i on
bi ndi ng t o , w-di ami ne was st udi ed usi ng
el ect r o sp ar y i o n i zat i o n an d t h eo r et i cal
cal cul at i ons.
List of Processes / Technologies Developed and
their Importance
O A process usi ng Zeol i t e as st at oonary phase
h as b een d evel o p ed f o r t h e syn t h esi s o f
Po r p h r i n s, Cal i x(4, Pyr r l e an d 2 met h yl
napt hoqui nol i ne (vi t ami n K-3)
O An act ive mosquit o repellant process has been
d evel o p ed u si n g Ch l o r o xyl o n sw i et en i a
essent i al oi l s.
Chemical & Instrument Analysis
MALDI - TOF Mass Spectrometer
66
* X-RAY CRYSTALLOGRAPHY CENTRE
The Cent er has est ablished a st at e-of-t he-art facilit y for
t hree-dimensional st ruct ure elucidat ion (APEX SMART
CCD Si ngl e Cryst al X-ray Di ffract omet er) and mat eri al
char act er i zat i on (Br uker D8 Advance Powder X-r ay
Di f f r act o met er ). To d ay, t h e g r o u p en j o ys a w el l -
est ablished reput at ion amongst indust ry and academia
f o r i t s co n t r i b u t i o n s i n d r u g p o l ymo r p h i sm an d
elucidat ion of complex molecules (ambiguous t hrough
spect roscopi c t echni ques).
The Cent er has built up an excellent Inst it ut e Indust ry
n et w o r k. Fr o m j u st samp l e an al ysi s an d
ch ar act er i zat i o n i n t h e ear l i er year s, t h e X- r ay
Cryst al l ographi c Cent er has t oday met amorphosi zed
i n t o a w el l - est ab l i sh ed cen t er f o r co n d u ct i n g
p ol ymor p hi sm st ud i es of d r ug mol ecul es t ow ar d s
Regulat ory, IPR and US FDA requirement s. A not ewor t hy
cl i ent el e of maj or p har maceut i cal comp ani es vi z.,
Merck, Ind-swif t , Torrent , Cadila, Lupin, IPCA, USV, Nat co,
Dabur, et c., st and t est i mony t o t he exper t i se of t he
Cen t er i n d r u g p o l ymo r p h i sm st u d i es, p r o d u ct
charact erizat ion and qualit y cont rol issues.
The current research on novel drug molecule t owards
st r u ct u r e act i vi t y r el at i o n sh i p u si n g x- r ay
cr yst al l og r ap h i c st ud i es h as f et ch ed t h e Cen t er a
u n i q u e i d en t i f i cat i o n i n t h e ar ea o f ch emi cal
cr yst al l ography. It i s not ewor t hy t hat several cr yst al
st ruct ures el uci dat ed by t he Cent er has resul t ed i n
p u b l i cat i o n i n l ead i n g i n t er nat i o n al j o u r n al s. The
Cen t er s o w n cr yst al l o g r ap h i c r esear ch h as al so
r esu l t ed i n 23 r esear ch p ap er s i n i n t er n at i o n al
cryst al l ographi c j ournal s.
* HPLC/ UV GROUP OF ACD
* BASIC RESEARCH
O Isol at i on, puri fi cat i on and charact eri zat i on of
High Resolution ESI - Q TOF Mass Spectrometer
A Close view & Gas Chromatograph - Mass
Spectrometer (GC-MS) vis Micromass 70-70H
Gas Chromatograph - Mass Spectrometer (GC - MS)
AUTOSPEC M
Ion Chromatograph
67
minor impurit ies and degradat ion product s of
bul k drugs (vi z; Ast raxant hi n, Cycl ospori n A,
Cef uroxi me Axet i l , Bi sacodyl et c.) by Prep LC,
FT-IR, MS and NMR.
O Enant iomeric resolut ion st udies of chiral drugs
and t heir synt het ic precursors (viz; Mosapride
ci t r at e, Ci t al o p r am, d o xazo si n mesyl at e,
Rab ep r azo l e, Bi cal t ami d e et c.) b y
polysaccharide based chiral st at ionary phases
(CSPs) u si n g p h o t o d i o d e ar r ay an d
p o l ar i met r i c d et ect o r s. Co mp ar i so n o f
resol ut i on st udi es usi ng b-CDs, crownet hers
as mobile phase addit ives by HPLC.
O Devel o p men t an d val i d at i o n o f l i q u i d -
chromat ographi c met hods for det ermi nat i on
of process rel at ed i mpuri t i es of Mosapri de,
Venalafaxine, doxazosin, Valdecoxib, et oricoxib,
Paracet amol et c.
*APPLIED RESEARCH
O Devel opment of ext ract i on procedures (i .e.
soxlet t and liquid phase) and det erminat ion of
Solanesol from t obacco leaves by RP-HPLC.
O Devel op ment of ext r act i on p r oced ur es (i .e.
l i qui d phase) and resi dual det ermi nat i on of
Azadi racht i n from neem cake oi l and t obacco
leaves by RP-HPLC.
* NUCLEAR MAGNETI C RESONANCE
SPECTROSCOPY
The act i vi t i es of t he group i nvol ve t he st udy of t he
mol ecul ar st ruct ure, conf ormat i on and dynami cs of
molecules of int erest in chemist ry and biology and t o
provide efficient and st at e of t he art analyt ical support
t o t h e sci en t i f i c p r o j ect s i n t h e i n st i t u t e an d t h e
academic and indust rial users all over t he count r y. IICT
h as d evel o p ed exp er t i se i n t h e ar ea o f NMR
spect roscopy i n l i qui ds, l i qui d cryst al s and sol i d st at e
and magnet i c resonance i magi ng. St udy of st ruct ures
and conformat i ons of novel mol ecul es and mol ecul ar
mot ions in confined geomet ries are t he niche research
areas of t he group.
OResearch act ivit y: The main emphasis of t he research
act i vi t y h as b een o n t h e st u d y o f t h e st r u ct u r e,
co n f o r mat i o n an d d yn ami cs o f p ep t i d es,
p ep t i domi met i cs and novel or gani c mol ecul es and
mo t i o n o f mo l ecu l es i n r est r i ct ed g eo met r i es.
Conf or mat i onal r est r i ct i ons, ami d e b ond i sost er es,
modificat ions of nat ive pept ide backbone are very oft en
used in t he mimicry of t he pept ide scaffolds. This group,
desi gned and carri ed out ext ensi ve st ruct ural st udi es
on pept ides cont aining higher homologues of - amino
acids, which is a nat ural ext ent ion in t he backbone space
o f t h e p ep t i d o mi met i cs an d al l evi at es t h e
d i sad van t ag es o f t h e co n ven t i o n al p ep t i d es as
t h er ap eu t i c ag en t s. Th e act i vi t y i n t h i s ar ea
encompasses st udies of bot h linear, cyclic and pseudo
pept ides. The capabilit y of NMR spect roscopy t o probe
syst ems at molecular level and providing bot h st ruct ural
and dynamical informat ion was ut ilized t o invest igat e
liquid cryst als, polymers and t hin films.
O Pept i des wi t h - ami no aci ds: Th e -p ep t i d es,
ol i gomers of -ami noaci ds, adopt a vari et y of novel
seco n d ar y st r u ct u r es. Mi xed 10/ 12- h el i ces, w i t h
int ert wined 10- and 12- membered H-bonds, are unique
t o t hi s cl ass of mol ecul es. NMR and CD spect roscopy
were used t o show t hat very small oligomers of a new
f ami l y of C-l i nked carbo -pept i des obt ai ned f rom C-
l i nked carbo b-ami no aci ds (Caa) depi ct ri ght handed
10/ 12- and 12/ 10- helices. The observat ion of such short
hel i ces i n t ri and t et ra pept i des was unprecedent ed.
The uni que desi gn uses t he concept of al t ernat i ng
chiralit y. Two epimers of Caa, wit h R and S chiralit y at
t he -carbon, were alt ernat ingly used in t he sequence.
In order t o relieve t he st eric st rain caused by t he bulky
sugar rings, mixed pept ides cont aining Caa and h-Gly, a
-ami no aci d wi t h no si de chai ns, were i nvest i gat ed.
These resul t s demonst rat ed t hat Caa resi dues di ct at e
t he conformat i on of -h-Gl y, l eadi ng t o t he mol ecul es
depi ct i ng novel 10/ 12- and 12/ 10- l ef t handed mi xed
helices in addit ion t o t he right handed mixed helices.
14-h el i x i s an ot h er i n t er est i n g cl ass of secon d ar y
st r uct ur es ob ser ved i n -p ep t i d es. A new f ami l y of
oligomers from ci s--sugars (Saa) showed well defined
r i g h t h an d ed h el i ces. Accommod at i on of h -Gl y i n
68
ol i gomers arranged wi t h al t ernat i ng Saa and h-Gl y
showed t hat very robust 14-helices can be obt ained in
pept i des cont ai ni ng as f ew as t hree resi dues. A new
family of 9/ 11 helices were obt ained from a/ - pept ides
der i ved f rom di pept i de repeat of L-Al a and Caa. The
availabilit y of such a wide variet y of short helices is an
import ant st ep in creat ing and designing well defined
t ert iary st ruct ures, a necessary requirement for having
new family of molecules wit h t he funct ional propert ies
like t hose of biopolymers.
O Pept ides wit h -amino acids: In addi t i on t o t he
helices, ot her ubiquit ious class of secondary st ruct ures
present i n pept i des and prot ei ns i s a -hai rpi n. These
st ruct ural element s, specially t he segment , t hat enables
t he change in t he direct ion of t he pept ide chain, play a
O Pept i des wi t h - ami no aci ds: Th e p ep t i d es
cont ai ni ng -ami no aci ds, bel ongi ng t o t he f ami l y of
conf ormat i onal l y rest ri ct ed sugar ami no aci ds, were
ext ensi vel y st udi ed. The O-benzyl pr ot ect ed l i near
t et ramer of 6-ami no-2,5-anhydro-6-deoxy-D-gl uconi c
aci d (Gaa) was shown t o t ake a wel l def i ned hel i cal
st ruct ure wi t h t hree repeat ed -t urns ari si ng due t o
t he 10- membered H-bonds bet ween t he carbonyl of
first Gaa wit h t he amide prot on of t he t hird Gaa residue,
Pyrroleamino acid (Paa), which behaves like a rest rict ed
di pept i de i sost ere of Gl y-dehydroal ani ne, was shown
t o t ake an ext ended conformat ion and pept ides having
t hem generat e st abl e -hai rpi n wi t h appropri at e t urn
mot i f. Cycl i c t ri -pept i de of mannose deri ved furanoi d
sugar amino acids showed a conformat ion where t he
ami de and t he carboxyl f unct i onal i t i es were on t he
op p osi t e si de of t he r i ng. Cycl i c d i p ep t i d e of Gaa
result ed in an unusual six membered H-bond bet ween
Gaa NH and neighbouring Gaa C3OH.
very import ant role in t he prot ein funct ion. In an effort
t o invest igat e t he st abilit y of such st ruct ures, 3 amino-
benzoic acid (Aba), a -amino acid, was incorporat ed in
a designed -hairpin. It was found t hat Aba is very well
t ol erat ed i n t he -hai rpi ns and does not compromi se
t hei r st abi l i t y. Addi t i onal l y, i t was observed t hat Aba
permit s generat ion of st able -hairpins for a variet y of
t urn mot ifs, due t o dampening of t he nat ural t wist of
t he st rands because of t he planar ext ended geomet ry
of Aba. A vinylogous proline (V Pro) mot if wit h a ci s
amide bond was used t o nucleat e a novel 12-membered
t urn mot i f i n t he desi gned pept i des, whi ch st abi l i zes
t he -hai rpi n st ruct ure.
69
O Ot her pept ides: Several ot her pept ides and pseudo
pept ides, bot h linear and cyclic, were invest igat ed. The
drive for such st udies arises from t he usual observat ion
t h at t h e co n f o r mat i o n al r est r ai n t s ar i si n g d u e t o
cycl i zat i o n may p r e- i n t r o d u ce t h e b i o act i ve
co n f o r mat i o n i n t h e mo l ecu l e. Cycl i c p ep t i d es
cont aining het erochiral D-Pro-L-Pro di-pept ide t emplat e
were shown t o t ake 3
10
hel i cal st ruct ure. Ut i l i zi ng t he
hi gh propensi t y of prol i ne t o have ci s ami de bonds,
st ruct ures of several cycl i c pept i des wi t h very l arge
p o p u l at i o n s w i t h ci s ami d e b o n d s, w h i ch d i sp l ay
int erest ing t urns, were st udied.
O Novel organic molecules: Mol ecul ar st ruct ures of
several i nt erest i ng organi c mol ecul es were deri ved.
Del i neat i on of t he mol ecul ar st ruct ures has hel ped i n
u n d er st an d i n g t h e i n t r i caci es o f t h e r eact i o n
mechani sms i nvol ved i n t he chemi cal react i ons. The
unusual f ormat i on of benzof used het erocycl es i n t he
ami nogl ycosi dat i on of C-gl ycosi des was underst ood
wi t h t he hel p of some det ai l ed and i nci si si ve NMR
experi ment s, whi ch hel ped i n deci pheri ng t he novel
react i on pat hway.
O NMR st udies of soft solids :
129
Xe NMR is a versat ile
t o o l t o st u d y mo l ecu l ar mo t i o n s i n co n f i n ed
geomet ries.
129
Xe chemical shift s and relaxat ion t imes
w er e u sed t o i n vest i g at e t h e p h ase t r an si t i on s i n
nemat ic and smect ic liquid cryst als. A t heoret ical model
was developed for underst anding t he xenon chemical
shi f t s and was appl i ed t o 4-4-di hept yl azoxybenzene.
The monit oring of t he hydrophilic-hydrophobic t hermal
swit ching in polymer gels using
129
Xe NMR,
1
H magnet ic
resonance i magi ng and f i el d-cycl i ng NMR has been
i nvest i gat ed.
1
H mul t i pl e quant um NMR was used t o
st u d y u l t r a t h i n l i p i d an d p o l ymer f i l ms f o r
under st andi ng t he dynami c het er ogenei t y and t he
su r f ace i n d u ced o r d er. Mo l ecu l ar d yn ami c
het erogenei t y of monol ayer t o submonol ayer l eci t hi n
f i l ms conf i ned i n sub mi cr on cyl i ndr i cal p or es wer e
i n vest i g at ed b y mag n et i zat i o n exch an g e u si n g a
double quant um dipolar filt er.
O St udies on minerals : These invest igat ions are part of
an act i ve co l l ab or at i o n w i t h Dr. G. Par t h asar at h y,
Nat ional Geophysical Research Inst it ut e. The result s on
Prot erozoic shungit e from shungit e mines, Russia and
Cret aceous Ter t iary boundry layer in Anj ar, India, solved
t he cont roversy around t he prevalence of fullerenes in
nat ure. In Anj ar samples, t he associat ion of fullerenes
wit h high iridium concent rat ion suggest s t hat t hey can
be used as marker of an ext ra t er rest r i al i mpact . The
st ud i es r esul t ed i n f i nd i ng t he new occur r ence of
moganit e, a fibrous form of microcryst alline silica, and
ferrous saponit e in Deccan flood basalt .
O S&T Services : NMR group has provided spect ra for
more t han 75,000 samples t o t he users in t he laborat or y,
in addit ion, NMR spect ra for about 3,700 samples were
run for ext ernal users during t his period.
* ISO QUALITY ASSURANCE CELL
IICT ISO Cell is accredit ed wit h ISO-9001-2000. This cell
has cat ered t o t he needs of nat ional indust ry, academia
an d ot h er g over n men t ag en ci es. It h as p r ovi d ed
ser vi ces t o 277 cl i en t s w h o ut i l i zed i n st r umen t al ,
analyt ical ser vices such as HPLC, XRD,SEM, Paper t est ing,
NMR, DSC et c. Maj or client s who ut ilized services are
Het ero Drugs Lt d. (Hyderabad), Sandoz Pvt . Lt d. (Thane),
AVRA Lab or at o r i es Lt d. (Hyd er ab ad ), Neu l an d
Lab or at or i es Lt d . (Med ak), Jub i l ant Or ganosys Lt d .
(Myso r e) Vi r ch o w Lab s Lt d. (Hyd er ab ad ), Nect ar
Laborat ories Lt d. (Hyderabad), SMS Pharmaceut icals Lt d.
(Med ak), APL Resear ch Cen t r e (Hyd er ab ad ), Di vi s
Laborat ories Lt d., (Hyderabad), Dr. Reddys Laborat ories
Lt d. (Bol l aram), Bi ol ogi cal E.Lt d. (Hyder abad), VIMTA
Laborat ori es Lt d. (Hyderabad) and Ni chol as Pi ramal
India Lt d. (Hyderabad) and academic inst it ut es such as
Un i ver si t y o f Hyd er ab ad (Hyd er ab ad ) An d h r a
Universit y (Visakhapat nam), NIN (Hyderabad) et c.
70
* AN INTEGRATED INFORMATION SYSTEM
FOR THE CONTROL OF BANCROFTI AN
FILARIASIS IN ANDHRA PRADESH
Fi l ari asi s has been est i mat ed t hat i n Indi a about 454
mi l l i on p ersons are exp osed t o t he ri sk of Fi l ari asi s
disease. Nearly 28 million persons harbor microfilariae
in blood and about 21 million persons suffer from filarial
di sease mani f est at i ons.
To cont rol t he disease it is necessary t o communicat e
t he disease spect rum t o t he concerned healt h officials,
hence t he present st udy has been t aken up. The main
obj ect ive of t he program is t o develop t he Geographic
Inf ormat i on Syst em f or mappi ng of epi demi ol ogi cal
zones and pri ori t i zat i on of epi demi c zones by usi ng
cl ust er anal ysi s t echni ques.
OMapping of Endemic Zones: A Geographic Informat ion
Syst em (GIS) is a comput er-based t ool for mapping and
analyzing t hings t hat exist and event s t hat happen on
eart h. GIS t echnol ogy i nt egrat es common dat abase
operat i ons such as query and st at i st i cal anal ysi s wi t h
t he unique visualizat ion and geographic analysis benefit
o f f er ed b y map s. Fo u r d i st r i ct s f r o m AP i .e., East
Godavari , West Godavari , Kari mnagar and Chi t t or are
select ed for t he st udy. Nearly 8,000 blood samples were
col l ect ed f rom 40 vi l l ages of t hree di st ri ct s i .e., East
Godavar i (10), West Godavar i (10), Chi t t oor (10) and
Kari mnagar (10) t o anal yze t he parasi t i c l oad i n t he
communi t y. Ind oor -r est i ng mosq ui t oes ar e b ei ng
co l l ect ed at mo n t h l y i n t er val s w i t h t h e h el p o f
mechani cal aspi rat ors (Hausherr s machi ne Works, NJ,
USA) during 06:00 t o 09:00 hours from t he st udy areas.
Applicat ion of Self Organizing Map (SOM) t o priorit ise
t he endemic zone is under progress.
O An Integrated rural development programme
t hrough sericult ure at Kandukuru village of RR
Dist., AP
Thi s rural devel opment proj ect has sanct i oned under
CSIRs Rural Act i on Pl an. The proj ect si t e i s l ocat ed at
Kan d u ku r u vi l l ag e, RR Di st , AP, 32 Kms f r o m IICT,
Hyderabad. This village is a non-t radit ional sericult ure
area. Hence, t his project is proposed in Kandukuru village
for t he uplift ing rural economy of t his village.
Farmers of t his village are progressive and found t o be
more int erest ed t owards implement at ion of sericult ure.
Ten t housand mulberry cut t ings were plant ed in 2 acres
of a l and and proper i rri gat i on f aci l i t y has provi ded.
BIOLOGY BIOLOGY BIOLOGY BIOLOGY BIOLOGY
Management of mulberry plantation at Kandukuru village
High yielding VI Mulberry Plantation
71
This proj ect has commenced wit h specific obj ect ives t o
creat e self employment and income generat ion for t he
rural peopl e. The mai n obj ect i ves of t he proj ect s are
est abl i shment of mul berry garden wi t h hi gh yi el di ng
mulberry variet y,Implement at ion of package of pract ice
for mulberry cult ivat ion, rearing act ivit ies of silkworms
f o r o b t ai n i n g b et t er co co o n cr o p an d t r ai n i n g
programs on various act ivit ies in sericult ure.
For conduct ing t raining on rearing act ivit ies, a low cost
model rearing house has been const ruct ed. Nearly 40
farmers (progressive and new) were t rained in different
act ivit ies on mulberry cult ivat ion and disease and pest
management in sericult ure.
* CSIR CO-ORDINATED PROJECT
Isolation of collagen from marine sponges
Col l agen i s a fi brous prot ei n found ubi qui t ousl y i n al l
mul t i cel l ul ar an i mal s. It i s a p ar t i cul ar l y r i g i d an d
inext ensible ext racellular mat rix prot ein t hat serves as
a maj or const it uent of many connect ive t issues. Many
pharmaceut ical applicat ions are known for collagen, e.g.
sh i el d s, i n j ect ab l e d i sp er si o n s, sp o n g es an d
mi cr op ar t i cl es. Fur t her mor e, col l ag en i s used as a
moi st ur i zer i n cosmet i c creams. Cur rent l y, cat t l e are
t he main source for collagen because of t he reasonable
cost s f or t he mat eri al and t he avai l ab l e knowl edge
about i t s use. The use of bovi ne ori gi nat ed col l agen
has t o b e reconsi dered b ecause of t he ri sks of BSE
(b ovi n e sp o n g i f o r m en cep h al o p at h y) an d TSE
(t ransmi ssi bl e spongi f orm encephal opat hy). It has
been banned by most of t he advanced count ri es and
f ocused t hei r at t ent i on t o search f or an al t ernat i ve
origin of suit able collagen. During t his process we have
concent rat ed on marine sponges as a source of collagen
f rom mari ne ori gi n. We have i dent i f i ed few pot ent i al
candidat es and t heir cell cult ures are also init iat ed by in
vi t ro met hods.
O DOD-Sponsored project
Bi o-eval uat i ons f or newer pest i ci dal mol ecul es f rom
marine origin Marine organisms provide a very pot ent ial
source f or bi ol ogi cal l y act i ve compounds, and i nt er
di sci pl i nary approach by bi ol ogi st s and chemi st s can
pay rich dividends in t he exploit at ion of t his source t o
derive many act ive compounds. Usefulness of marine
fl ora and fauna as ant i -bact eri al , ant i -vi ral , ant i -t umor
an d o t h er b i o l o g i cal l y act i ve ag en t s h ave b een
report ed. Less at t ent i on has been f ocused t o screen
t he mari ne nat ural product s as pest i ci dal mol ecul es.
Th oug h t h e l i t er at ur e i n d i cat es t h at sever al l ar g e
number of novel mari ne nat ural product s, onl y a f ew
have r ecei ved ad eq uat e at t ent i on w i t h r esp ect t o
pest icidal screening. Past t wo decades, Biology division
of IICT has evaluat ed t housands of marine crude ext ract s
and ident ified t hree novel st ruct ures as insect growt h
regulat ors (US - Pat ent has been grant ed).
O Development of alt ernat ives t o t radit ional
acute toxicity tests
Worl d wi de, i n t he l ast 10 years numerous al t ernat i ve
t o xi co l o g i cal met h o d s h ave b een d evel o p ed an d
p r o p o sed i n p l ace o f st an d ar d an i mal t est s f o r
regulat ory safet y evaluat ions. Alt ernat ive t est met hods
are t hose t hat incorporat e some aspect of replacement ,
reduct ion or refinement of animal use compared t o t he
corresponding t radit ional t est . Irrit at ion and corrosion
st udi es f or t he eye assess t he short t erm ef f ect s of
mat eri al s whi ch ei t her have a si gni f i cant pot ent i al t o
accident ally end up on t he eye, or are int ended t o do
so , f o r examp l e, p h ar maceu t i cal s, p er so n al car e
product s. These t est s have been in exist ence since t he
1030s. These i n vi vo met hods used rabbit s and guinea
pi gs f or eval uat i on of mat eri al s f or t hei r pot ent i al t o
cause eye irrit at ion. The necessit y of using t hese whole
animal models has been t he subj ect of debat e among
scient ist s and ant ivivisect ionist s over t he last 20 years.
Hen ce, w i t h t h e vi ew o f set t i n g u p f aci l i t i es f o r
al t ernat i ve t oxi col ogi cal met hods f or al t ernat i ves f or
Biology
72
ocul ar t oxi ci t y, work has been i ni t i at ed. Eval uat i on of
acut e ocular t oxicit y of some of t he pest icides using i n
vi vo red cell t est syst em has been carried out and will
be sent for publicat ion short ly.
O Post Harvest Prot ect ion of Maize from Pest s
and Diseases in Southern India. TMOP (MAIZE)
It is aimed at developing plant based pest icide t o combat
bot h i nsect pest s as wel l as fungal pat hogens i n fi el d
condit ions so, t hat t he t oxic synt het ic pest icides can be
avoided in food product s.
Leaves of si x i ndi genous pl ant s were col l ect ed and
Soxhl et ext ract ed. The crude ext ract s were separat ed
on si l i ca gel col umn. The resul t ant chromat ographi c
fract ions as well as crude ext ract s were bioassayed. In a
f umi g at i on met hod f or i nsect i ci d al act i vi t y and Y-
olfact omet er for repellent act ivit y against t he t wo maj or
pest s of st ored maize, Si t ophi l us oryzae and Rhi zopert ha
domi ni ca.
The aqueous ext ract s of t he above pl ant s were al so
evaluat ed for t heir ant ifungal act ivit y t o t he t oxigenic
st r ai n of Asper gi l l us f l avus. Bi ochemi cal st ud i es on
qual i t at i ve & quant i t at i ve changes of t he pest s and
f ungal i nf est ed mai ze are i ni t i at ed. About f our pl ant
ext ract s exhibit ed excellent insect icidal act ivit y and are
promising for t he development of a bot anical pest icides
for t he use in st ored maize. Pat ent s were submit t ed for
approval .
OAdvanced Course in Bioinformat ics
A u n i q u e p r o g r am o n Ad van ced Co u r se i n
Bioinformat ics (ACB) was init iat ed in collaborat ion wit h
Cent re f or Advanced Comput i ng (CDAC) Hyderabad
and JNTU Hyderabad in 2002. The main obj ect ive of t his
course is t o provide an insight int o t he value of rapid
access t o sci ent i f i c i nf or mat i on f or ed ucat i on and
research purposes. It i s desi gned i n such a way t hat
st udent will get an exposure t o t he various import ant
modules of bioinformat ics and st at e of art facilit ies like
opport unit y t o work on Super comput er PARAM 10000
and PARAM PADMA - The program i s a Fi ve mont hs
fullt ime course consist ing of t hirt een modules includes
Inf or mat i on Technol ogy, Bi ost at i st i cs, Genomi cs &
Prot eomics, St ruct ural Biology, Prot ein folding, Medical
In f o r mat i cs, Mo l ecu l ar Mo d el i n g , Seq u en ce
An al ysi s, Ph ar maco Ki n et i cs & En zyme Ki n et i cs
and Inst rument at i on Techni ques.
24 Candi dat es wi l l b e admi t t ed i nt o t he Advanced
Cour se i n Bi oi nf or mat i cs out of w hi ch 6 seat s ar e
r eser ved f o r i n d u st r y sp o n so r ed can d i d at es.
Can d i d at es w i l l b e ad mi t t ed on l y af t er q ual i f yi n g
Common Ent rance Test (CET). Thi s CET i s b ased on
Comp ut er Fund ament al s, Pr og r ammi ng Concep t s,
Biology Concept s and General Apt it ude.
Advanced Course in Bioinformatics - 2004 Batch, Dr. J.S. Yadav,
Director is presenting a memento to Dr. Javed Iqbal,
Director,Dr.Reddy Research Foundation
As on dat e t hree bat ches have been complet ed in t he
years 2002-2003,2003-2004,2004-2005, and t he present
bat ch for t he academic year 2005-2006 is ongoing. The
st udent s who have compl et ed t he course have been
wel l pl aced i n good i ndust ri es l i ke Ranbaxy, Rel i ance,
Jubl i ant Bi osys, Oci mum sol ut i ons et c. Some of t he
successful st udent s have gone abroad t o pursue higher
st udi es i n reput ed uni versi t i es.
73
The Pharmacol ogy Di vi si on of IICT i s i nvol ved i n t he
basi c, appl i ed and t echnol ogy ori ent ed research. The
pharmacol ogy di vi si on cat ers t o t he need of vari ous
pharma i ndust ri es, academi c i nst i t ut i ons and act i vel y
collaborat es wit h government agencies. The division is
engaged in screening t he new chemical ent it ies in t he
ar ea o f ar t h r i t i es, d i ab et es an d at h er o ch l o r o si s,
i dent i f i ed f ew new l eads i n t he area of art hri t i s and
diabet es. The basic research is in t he area of novel drug
delivery syst ems concerning t o t ransdermal, liposomal,
nanopar t i cl es and mi cro spheres et c.. The oral i nsul i n
t echnol ogy wi t h Vi t B12 has been grant ed US pat ent
and t he commercial negot iat ions are in progress. There
are ot her areas of invent ion, which are wit h respect t o
dendrimer as ant i-inflammat ory and herbal formulat ion
for diabet es. The pharmacology division involved in t he
CSIR net wor k program Ani mal model s and ani mal
subst i t ut e t echnol ogi es. The basi c i nf rast ruct ure has
b een d evel o p ed an d est ab l i sh ed a t i ssu e cu l t u r e
l aborat or y f or screeni ng t he compounds. There has
been excellent relat ions wit h pharma indust ry and t he
ECF earned by t he division is mainly from commercial
organizat ions. The division has been recognized by Drug
Co n t r o l Ad mi n i st r at i o n o f An d h r a Pr ad esh i n f o r
eval uat i ng t he qual i t y of t he f i ni shed product s f or a
pharma indust r y. The division has rendered ser vices t o
APHMHIDC and AIDS Cont rol Board, Hyderabad and
JIPMER, Pondicherry. Overall about 250 drugs have been
st and ar d i zed accor d i ng t o IP, BP and USP et c. The
di vi si on has qual i f i ed GLP and NABL i nsp ect or and
implement at ion of GLP and NABL is in progress.
O Techni cal ser vi ces provi ded t o Phar ma
Indust ries
' Acut e oral t oxi ci t y st udy of SMSRC 0401 t o M/ s
SMS Pharmaceut icals Lt d, Hyderbad
' Ant i-Inflammat ory Act ivit y Of Divi s Compounds By
Carragennan Induced Rat Paw Edema Model M/ s
Di vi s Laborat ori es Li mi t ed,, Hyderabad.
' Sub acut e t oxicit y st udy of wound healing pept ide
(GENOPEP) in rat s and rabbit s, Issar Pharmaceut icals
Pvt Lt d, Hyderabad
' Acut e Oral Toxicit y Of Cefpodoxime Proxet il In Mice
And Rat s t o M/ s APL Research Cent re, Hyderabad
' Acut e Oral Toxi ci t y St udy Of Lami vudi ne In Mice
And Rat s M/ s APL Research Cent re, Hyderabad .
OFinished Product evaluation services provided
t o
(a) APHMHIDC (b) AIDS Cont rol Board (c) 3.Jawaharlal
Inst it ut e of Post graduat e Medical Educat ion & Research
O Phar maceut i cal scr eeni ng of Her bal
formulation for
(a) Immunomodul at or y act i vi t y (b) Precl i ni cal Toxi ci t y
of Bhasmas provi ded t o Cent ral Counci l For Research
in Ayurveda & Siddha, Dept t . Of Ayush, Minist ry of Healt h
& Family Welfare, Govt of. India, New Delhi.
PHARMACOLOGY PHARMACOLOGY PHARMACOLOGY PHARMACOLOGY PHARMACOLOGY
Automatic Tissue Processor
74
* ENGI NEERI NG I NTENSI VE CHEMI CAL
PROCESSES AND SEPARATIONS
The group ai ms at t he devel opment of engi neeri ng
int ensive and eco-friendly processes of commercial or
st r at egi c i mp or t ance, ut i l i zi ng t he exp er t i se of t he
members i n t he speci al i sed subj ect s such as: react i on
en g i n eer i n g an d p r o cess d evel o p men t , p r o cess
d yn ami cs an d co n t r o l , p r o p er t i es eval u at i o n an d
membrane separat i ons.
* REACTION ENGINEERING AND PROCESS
DEVELOPMENT
* APPLIED RESEARCH
O Mononitrotoluenes
Pi l ot pl ant scal e process f or t he cont i nuous opt i mal
p r o d u ct i o n o f p ar a- n i t r o t o l u en e u si n g so l i d aci d
cat al yst , at 2-4 kg / hr of mi xed moni t r ot ol uenes i s
developed and ready f or demonst rat ion t o sponsor,
O Xylose and Xylotol
In vi ew of t hei r i mpor t ance as subst i t ut es f or sugar,
process devel opment act i vi t y f or t he product i on of
Xylose and Xylt ol have been init iat ed. The work aims at
t he product i on of Xyl ose or Xyl et ol f rom agri cul t ural
wast e product s. The i ni t i al r esul t s are encouragi ng.
St udies aiming at t he opt imizat ion of process condit ions
are i n progress. Scal e-up and f urt her st udi es wi l l be
t aken up on sponsorshi p.
* BASIC RESEARCH
As a corrolary t o t he problems encount ered during t he
on going proj ect s, as well as t he academic int erest s basic
st u d i es i n Ch emi cal React i o n En g i n eer i n g o n t h e
following t opics has been init iat ed.
O Mi cr o React o r Tech n o l o g y, w i t h t h e p r i mar y
obj ect ive of set t ing-up of a general purpose Micro-
react or Syst em f ol l owed by experi ment at i on on
sel ect ed react i ons.
O St u d i es o f Mu l t i p h ase React i o n s w i t h Sp eci al
Ref er en ce t o t h e Fo r mat i o n o f Ket azi n e(an
i n t er med i at e i n t h e eco-f r i en d el y p r ocess f or
hydrazi ne).
O OO OO Regio-select ive cat alyt ic Vapor Phase Al kylat ion of
Aniline using Clays
O OO OO Select ive Vapor Phase Et hylat ion using Zeolit es
O OO OO Bi o-r eact or s f or Cyan oh yd r i n Pr od uct i on w i t h
Novel Porous Vessel Bio-react or for react ions wit h
Immobilized Enzymes and Microbial Cells
O OO OO Microbial Oxidat ion of Alkanes
PROCESS DYNAMICS AND CONTROL
* APPLIED RESEARCH
Novel met hods have been devel oped i n t he f i el ds of
advanced process cont rol and on-line opt imizat ion, and
t hei r perf ormances are eval uat ed t hrough dynami c
si mul at i on i nvol vi ng t ransi ent and cont i nuous t i me
domain chemical processes.
Advanced Real-Time Cont rol Technology for Bat ch
React ors and Technology Upgradat ion
O OO OO Advanced Real -t i me Process Cont rol Technol ogy
C CC CCHEMICAL HEMICAL HEMICAL HEMICAL HEMICAL ENGINEERING SCIENCES ENGINEERING SCIENCES ENGINEERING SCIENCES ENGINEERING SCIENCES ENGINEERING SCIENCES
O Titanium Dioxide
Process for t he product ion of Tit anium Dioxide has been
t aken up under t he t ask f orce p roj ect s f or Gl ob al l y
Comp et i t i ve Technol o g i es. Chl or i ne r ecover y f r om
hydrochloric acid has been chosen for t he first phase of
t he i nvest i gat i on. Rel evant l i t erat ure survey has been
complet ed and good progress has been made t owards:
Procurement of Raw Mat erials and React or Fabricat ion
and Set -up. Some preliminary experiment s have been
con d uct ed maki n g use of a g l ass r eact or an d t h e
essent ial equipment s are being procured.
Mononitrotoluene pilot plant
75
f o r Bat ch React o r s a p r o j ect sp o n so r ed b y
Dep ar t men t o f Sci en ce an d Tech n o l o g y,
Go ver n men t o f In d i a h as b een su ccessf u l l y
complet ed and final report submit t ed.
O OO OO Aut ot uni ng PID cont rol has been est abl i shed f or
NMSM f ormat i on react i on and t he t echnol ogy i s
d emo n st r at ed t o SMS p h ar maceu t i cal s Lt d ,
Hyderabad.
Real - t i me p r o cess co n t r o l t ech n o l o g y h as b een
developed for a bat ch react or syst em by set t ing up an
exp er i ment al b at ch r eact or and connect i ng i t t o a
personal comput er f or on-l i ne dat a acqui si t i on and
co n t r o l . Op t i mal o p er at i n g co n d i t i o n s h ave b een
est ablished and aut omat ed operat ion has led t o higher
yi el d s an d con si st en t p r od uct q ual i t y i n b ot h t h e
i ndust ri al react i ons.
Aut omat ed solid pot assium hydroxide feeding wit h t he
help of a fabricat ed screw feeder arrangement coupled
wit h aut omat ic cont rol of t emperat ure wit h t he help of
co o l an t f l o w as t h e man i p u l at ed i n p u t h as b een
demonst rat ed t o SMS Pharma Indust ry t hat t he yi el d
has improved from 50 t o 65%.
St r eaml i n i n g an d mi n i mi zi n g t h e n u mb er o f
t emperat ure set point changes, reduct ion in bat ch t ime
from 12 t o 10 hours, modificat ion of t he feeding st rat egy
from bot h solid and liquid feeds t o only liquid feeding
st rat egy, improvement in yield from 48 t o 55% are some
of t he main achievement s in NMSM format ion react ion.
Real-t ime Cont rol t echnology has been demonst rat ed
t o SMS Pharmaceut i cal s Lt d. f or aut omat i on of sol i d
f eed and advanced cont rol of t emperat ure f or bet t er
and consist ent yield in dipot assium format ion react ion,
whi ch i s t he f i rst st ep i n t he preparat i on of t he drug,
ranit idine. Process is available for release t o ot her client s
on sponsorshi p.
O Artificial Intelligence Based Tools for Process
Modeling, Optimization and Control
A new dat a dri ven approach has been proposed f or
model i ng and t raj ect ory opt i mi zat i on of a bat ch or a
semi-bat ch process. The effect iveness of t he proposed
Art ificial Neural Net (ANN) based modeling and t raj ect ory
opt imizat ion scheme is demonst rat ed using simulat ion
st ud i es on a b enchmar k MIMO semi -b at ch p r ocess
repor t ed i n t he l i t erat ure. The resul t s of t hi s work are
included in a research paper published in Indust rial and
Engi neeri ng Chemi st ry Research.
EKF(Ext ended Kalman Filt er) is proposed as a cont roller
for cont rol est imat ion by incorporat ing different levels
of process knowledge for chemical engineering syst ems.
The concept of Ext ended Kal man Fi l t er cont rol l er i s
f u r t h er ext en d ed t o i n co r p o r at e t i me- d el ay
comp ensat i on. New p redi ct i ve and op t i mal cont rol
f ormul at i ons have al so been proposed usi ng t he EKF.
Part of t he work i s al so i ncl uded i n a t echni cal paper
communicat ed t o CHEMCON 2004, Dec. 27-30, 2004.
Two d at a-d r i ven mo d el b ased t r aj ect o r y t r ack i n g
cont rol al gori t hms have been proposed usi ng i nput -
out put dat a-dri ven model s (l i near-i n-paramet ers t i me
ser i es mo d el s w i t h t i me- var yi n g p ar amet er s an d
nonl i near Art i f i ci al Neural Net works) wi t hi n a Generi c
Model Cont rol(GMC) framework, and are evaluat ed by
applicat ion t o a mult i-product semi-bat ch polymerizat -
i on t emp er at ur e cont r ol chal l eng e p r ob l em and a
mu l t i var i ab l e semi -b at ch r eact o r p r o b l em. The
p er f o r man ce o f t h e EKF b ased GMC al g o r i t h m i s
compared t o t hat of an aut o-t uned PI cont rol l er f or
t emperat ure cont rol of t he exot hermi c bat ch react or
involving format ion of hexyl monoest er of maleic acid.
The result s of t his work are included in a t echnical paper
at CHEMCON 2004, Dec. 27-30, 2004.
Off-line opt imal cont rol approaches have been explored
for a t ernary bat ch dist illat ion column wit h slop recycle
for separat ion of a mixt ure of cyclohexane, n-hept ane
and t oluene using Pont r yagins Maximum Principle and
Cont rol Vect or Paramet eri zat i on. The st udy has been
f urt her ext ended t o evol ve on-l i ne opt i mal cont rol of
bat ch dist illat ion.
O Plant-Wide Control Design Procedure
The mai n obj ect i ves f or t hi s proj ect recent l y i ni t i at ed
are - t o design a plant -wide cont rol st ruct ure based on
d i f f er ent i al g eomet r i c ap p r oach, and t o ap p l y t he
pr oposed met hod t o Tennessee East man Chal l enge
Problem. The st udy has est ablished t hat incorporat ion
Chemical Engineering Sciences
76
of i nt eract i on f or cont rol can resul t i n consi derabl e
i mprovement i n cont rol performance.
* Facilit y Set-up
Experi ment al Bat ch React or real -t i me cont rol syst em
wit h PC based on-line dat a acquisit ion & cont rol wit h
sever al accesso r i es i n cl u d i n g a scr ew f eed er f o r
aut omat i c sol i d-f eedi ng and remot e-operat ed l i qui d
feed and cooling wat er pumps.
* BASIC RESEARCH
O OO OO Heat Release Est imat or Based Globally
Linearizing Control of a Chemical Reactor
Chemi cal react ors, especi al l y bat ch react ors occupy a
speci al posi t i on i n chemi cal processi ng i ndust ri es.
Real i zi ng t he advant ages of f er ed b y t he advanced
cont rollers, various model based cont rollers involving
rigorous process models have been report ed for bat ch
react ors. Al t hough ri gorous process model i s qui t e
useful in deriving efficient cont rollers, developing and
val i d at i n g r i g o r o u s mo d el s i n vo l vi n g r eact i o n
mechanisms and react ion kinet ics require considerable
t ime and effor t . Therefore, cont rol st rat egies based on
models t hat avoid react ion kinet ics and inst ant aneous
co mp o si t i o n measu r emen t s, b u t p r eser ve t h e
r i g o u r essn ess b y i n st an t an eo u s est i mat i o n o f
unknown informat ion are quit e beneficial. In t his st udy,
an energy model based globally linearizing cont roller
(EMBGLC) su p p o r t ed b y a d et er mi n i st i c f i l t er i s
present ed f or t emperat ure cont rol of an exot hermi c
bat ch react or. The det erminist ic filt er is used t o est imat e
t he rat e of heat release required for t he cont roller. The
result s of t he EMBGLC suppor t ed by t he det erminist ic
fi l t er are compared wi t h t he EMBGLC based on ot her
det erminist ic heat release est imat ors including a direct
energy balance and a kinet ic rat e expression. The result s
show t hat t he EMBGLC based on det er mi ni st i c f i l t er
p r ovi d es b et t er p er f or man ce f or t h e t emp er at ur e
con t r ol of t he exot her mi c b at ch chemi cal r eact or.
[ Indi an Journal of Chemi cal Technol ogy, 10, 539-544
(2003)]
O OO OO Fuzzy Adapt ive Cont roller for pH
Cont r ol of p H Pr ocesses i s ver y d i f f i cu l t d u e t o
nonl i near dynami cs, hi gh sensi t i vi t y at t he neut r al
point , and changes in t he concent rat ions of known or
unknown chemi cal speci es. In t hi s st udy, a d ynami c
fuzzy adapt ive cont roller (DFAC) wit h a new inference
mechanism is proposed and applied for t he cont rol of
nonlinear pH processes. The DFAC consist s of a low level
basi c cont rol phase wi t h a mi ni mum rul e base and a
hi gh l evel dynami c l earni ng phase wi t h an updat i ng
mechani sm t o i nt eract and modi f y t he cont rol rul e
base. The DFAC can sel f adj ust i t s f uzzy cont rol rul es
usi ng i nf or mat i on f r om t he p r ocess dur i ng on-l i ne
cont rol and creat e new f uzzy cont rol rul es or modi f y
t he present cont rol rul es usi ng i t s l earni ng capabi l i t y
from past cont rol t rends. The cont roller is evaluat ed by
applying it t o a weak acid-st rong base pH process wit h
input dist urbances and anot her pH process t hat involve
changes in acidic/ buffering st reams. The result s of t he
DFAC wit h t he new inference mechanism is compared
w i t h t h e kn ow n i n f er en ce mech an i sms, t h e f uzzy
cont roller, t he convent ional PI cont roller and also wit h
t h e ad ap t i ve PID con t r o l l er. Th e p r o p o sed DFAC
provi des bet t er perf ormance f or set poi nt t racki ng of
t he pH and rej ect ion of load dist urbances and buffering
af f ect s.[ Chemi cal Engi neeri ng Communi cat i ons, 191,
1564-1588 (2004)]
O OO OO Dat a Driven Modeling and Opt imizat ion of
Semibatch Reactors Using Artificial Neural
Net works
In t his st udy, a dat a driven approach has been proposed
for modeling and t raj ect ory opt imizat ion of a bat ch or
a semi b at ch p r o cess. Th e ap p r o ach i s b ased o n
paramet ri zat i on of i nput and out put t raj ect ori es as
f i n i t e d i men si o n al vect o r s u si n g o r t h o n o r mal
polynomials. Using input / out put t raj ect ory informat ion
avai l abl e i n hi st ori cal dat a bases, an art i f i ci al neural
net work (ANN) based model has been devel oped f or
cap t u r i n g t h e d yn ami cs o f semi b at ch p r o cesses
operat ed over a fixed int erval of t ime. The paramet rized
input t raj ect ories, init ial st at es, and process paramet ers
are considered input s t o t he ANN model, which predict s
out put s i n t erms of f ouri er coef f i ci ent s. The resul t i ng
algebraic model is used t o formulat e an opt imal cont rol
p r ob l em, whi ch can b e sol ved usi ng convent i onal
nonlinear programming t echniques t o generat e open-
loop opt imal input policies. The proposed ANN based
77
mo d el i n g an d t r aj ect o r y o p t i mi zat i o n sch eme i s
evaluat ed t hrough simulat ion st udies using a mult iple
i nput -mul t i pl e out put semi bat ch process. The resul t s
show t he ef f ect i veness of t he proposed scheme f or
t r aj ect o r y o p t i mi zat i o n o f semi b at ch p r o cesses.
[Indust rial & Engineering Chemist ry Research, 43, 7539-
7551 (2004)]
O OO OO Dynamic Recurrent Radial Basis Funct ion
Net wor k Model Pr edi ct i ve Cont r ol of
Unstable Nonlinear Processes.
Model predict ive cont rol (MPC) is known t o be a very
powerful cont rol st rat egy for a variet y of chemical and
biochemical processes. In t his st udy, A mult ist ep model
p r ed i ct i ve co n t r o l st r at eg y b ased o n d yn ami cal l y
recurrent radi al basi s f unct i on net works i s proposed
for single-input single-out put (SISO) cont rol of uncert ain
nonlinear processes. The cont rol syst em consist s of t wo
aut omat ically configured radial basis funct ion net works,
a t rained net work represent ing t he plant model and a
net work wit h on-line learning t o funct ion as cont roller.
Th e au t o mat i c co n f i g u r at i o n an d l ear n i n g o f t h e
net works i s carri ed out by usi ng a hi erarchi cal l y sel f
organi zi ng l earni ng al gori t hm. Thi s cont rol st rat egy i s
st ruct urally simple and comput at ionally efficient since
a si ngl e out p ut nod e of each r ad i al b asi s f unct i on
net wor k (RBFN) i s conf i gur ed t o p r ovi d e mul t i st ep
p r ed i ct i o n s f o r p l an t o u t p u t an d con t r o l l er. The
p er f or mance of t he p r op osed r ad i al b asi s f unct i on
net work model predi ct i ve cont rol (RBFNMPC) st rat egy
i s eval uat ed by appl yi ng t o t wo unst abl e nonl i near
ch emi cal p r o cesses, a ch emi cal r eact o r an d a
bi ochemi cal react or, and al so a st abl e pol ymeri zat i on
react or. Furt her, t he result s of t he RBFNMPC is compared
wit h similar RBFN model based cont rol st rat egies and
also wit h well t uned PID/ PI cont roller. The result s show
t he bet t er performance of t he proposed RBFNMPC for
t he cont rol of open-loop unst able nonlinear processes
t hat exhi bi t mul t i pl e st eady st at e behavi or. [Chemi cal
Engineering Science, 60, 6717-6731(2005)]
* PROPERTIES EVALUATION
Measurement of t hermophysical propert ies t o cat er t o
t he requi rement s of i n-house or out si de users and of
academic int erest , employing t he available facilit ies is
cont inued. During t he period, dat a on - densit y, viscosit y
and specific heat of liquids, solid-liquid phase t ransit ions,
specific heat and t hermal conduct ivit y of solids - of over
125 sampl es at t he condi t i ons of i nt erest (most l y of
out side users) has been provided. Result s of t he work,
carried out on t he basis of academic int erest (most ly on
isobaric vapor-liquid equilibria and excess ent halpies of
binay liquid mixt ures) at ambient pressure, have been
published in int ernat ional j ournals.
O Monographs
Pr ep ar at i o n o f mo n o g r ap h s o n t h er mo p h ysi cal
p r op er t i es of gases, l i qui ds and mi xt ur es has b een
init iat ed in associat ion wit h ot her int erest ed colleagues.
Fi rst draf t of t he manuscr i pt of a book Vi scosi t y of
Li q ui d s i n cor p or at i n g met h od s of : measur emen t ,
correl at i on and predi ct i on and avai l abl e expri ment al
dat a is ready and effort s are on t o complet e it and send
it t o t he publisher.
Aiming at improvement t o t he act ivit ies, t he following
b asi c st ud i es have b een i ni t i at ed wi t h t he hel p of
research fel l ows.
O OO OO PVT Relat ions of Fluids
O OO OO Vap or-Li qui d Equi l i br i a of Sel ect ed Bi nar y
Mixt ures.
* MEMBRANE SEPARATIONS
Thi s act i vi t y i s cent red round t he devel opment and
t est ing of membrane based separat ion t echniques for
p r act i cal l y i mp or t ant mi xt ur e syst ems. The st ud i es
en co mp ass b o t h l i q u i d an d g as mi xt u r e syst ems
i nvol vi n g i on s an d r ad i cl es an d t h ei r t r an sf er. The
following import ant proj ect s have been complet ed.
O OO OO Inst al l at i on of Pervaporat i on, Gas Separat i on and
El ect rodi al ysi s Membrane Syst ems f or Cent re of
Excellence in Polymer Science, Karnat ak Universit y,
Dharwad
O OO OO In st al l at i o n o f El ect r o d i al ysi s Pi l o t Pl an t f o r
Demi n er al i zat i o n o f Mi l k f o r Per mi o n i cs
Membranes Privat e Limit ed, Vadodara
O OO OO Development of Membrane Technology for Nat ural
Gas Separat ion for ONGC (DSIR-PATSER)
78
O OO OO Ext ract i on of Impur i t y-Free Sodi um Thi ocyanat e
Aq u eo u s So l u t i o n o f No n o f i l t r at i o n f o r
Consolidared Fibres and Chemicals(CFCL), Haldia
To st rengt hen t hei r knowl edge base, t he members of
t he group init iat ed syst emat ic basic st udies on:
O OO OO Membrane Technol ogy for Pur i f i cat i on of nat ural
gas, and
O OO OO Syn t h esi s an d Ch ar act er i zat i o n o f Pr o t o n
Conduct ing Polymer Membranes.
* * * * *CHEMICAL PLANT DESIGN AND ENGINEERING
This group is engaged in upscaling processes developed
by R&D divisions of IICT i.e. drugs, agrochemicals, bulk
organi cs, cat al ysi s et c., and col l ect s desi gn dat a f or
providing basic design for commercial plant s
Commercial soft ware packages like ASPEN PLUS, B-JAC
as wel l as t he sof t ware devel oped i n-house are now
used i n t hi s act i vi t y. Proper t y dat a bank i ncorporat ed
i nt o Aspen pl us i s of great hel p and reduces search
t i me co n si d er ab l y. Mod er n CAD p ack ag es ar e
ext ensi vel y used f or synt hesi s of process f l ow sheet s,
equi pment speci f i cat i ons pl ant l ay out drawi ngs, P&I
di agrams, pi pel i ne rout i ng di agrams and si ngl e l i ne
el ect r i cal d i agr ams and ot her r el at ed i t ems. Maj or
act ivit ies of t his group is given below:
* Plant Design and Basic Engineering
O OO OO Synthetic Aviation Lubricants:
On t he b asi s of d at a ob t ai ned on l ab or at or y scal e
experiment s conduced by Lipid Science and Technology
d i vi si on of IICT, a 5kg/ b at ch est er i f i cat i on r eact i on
syst em h as b een d esi g n ed , f ab r i cat ed an d
commi ssi oned t o p rep are p roduct samp l es of 5 kg
bat ch and also t o collect dat a for t he design of t he pilot
pl ant . The base oi l s meet i ng t he speci f i cat i ons were
short list ed for formulat ion and t est ing at consort ium
par t ner. As per t he mi cro pl an f our sampl es of SVS.1
base oil and one sample of SVS.2 base oil were sent t o
consort ium part ner for furt her evaluat ion, formulat ion
an d t est i n g. Th e SVS.1 samp l es wer e meet i n g t h e
sp eci f i cat i ons of MILPRF 23699F. SVS.2 samp l e was
meet ing t he specificat ions as per t he requirement s of
consor t i um par t ner. Desi gn of pi l ot pl ant of capaci t y
75-100 kg/ bat ch has been i ni t i at ed. Furt her work i n
opt imizing t he process paramet ers on 5-kg scale is in
progress.
O OO OO Biodiesel
Process development work for bio diesel from high FFA
oils and acid oils has been carried out in collaborat ion
wi t h l i p i d sci ence & t echnol ogy gr oup . A t wo-st ep
process of est erificat ion of FFA/ t rans-est erificat ion of
glycerides (Jat ropha) has been carried out on 1 kg per
bat ch scale. This process has been scaled up t o 50 kg oil
per bat ch and t he know-how is available for commercial
exploit at ion. The work on similar line using karanj a oil is
i n p r o g r ess. Sp o n so r ed b y TMOP & M mi n i st r y o f
agricult ure govt . of India, New-Delhi.
O OO OO Hydroxyet hyl Cellulose: A bench scale process for
HEC was developed. The bat ch size was 20 grams.
A know-how report has been prepared. Furt her
work t o develop a dry process for PIL is in progress.
(sponserer M/ s Pidilit e Indust ries Lt d., (PIL) Mumbai)
O OO OO Vinyl Chloride Monomer: Designed a cont inuous
laborat ory scale react or set up for t he preparat ion
of vinyl chloride monomer by t he oxychlorinat ion
of et hane. The rect or set up is t o be operat ed wit h10
g r am cat al yst . A t en d er d o cu men t h as b een
prepared f or f l oat i ng t ender f or t he f abri cat i on,
erect ion and commissioning of set up on a t urnkey
basis. This is a par t of t he proj ect Funct ionalizat ion
of al kanes awarded by CSIR t o IICT under New
Millennium Indian Technology Leadership Init iat ive
(NMITLI). Work is in progress.
Membrane separation bench scale unit
79
O OO OO Pyrazinamide: Engineering design report for 500
TPA pyrazinamide plant for SPIC Tut icorine, chennai,
have been prepared & submit t ed t o DSIR. Proj ect is
compl et ed.
O OO OO Government Opium & Alkaloids works: Det ailed
report s on t he following processes were prepared
and submit t ed t o GOAW.
a) Th e val i d at i o n o f p r o cess st u d i es o n t h e
ext ract ion of alkaloids from opium..
b) The improvement of t he efficiency of t he solvent
recovery in t he plant .
O Tet ra Bromo Bi s Phenol - A ( TBBA): The
cont inuous pilot plant for t he manufact ure of TBBA
50kg / h r w as er ect ed an d co mmi ssi o n ed
successf ul l y at Kar war. The p r ocess p ar amet er s
w er e o p t i mi zed b y o p er at i n g t h e p i l o t p l an t
con t i n uousl y. Fur t h er some mor e b en ch scal e
experiment s were conduct ed for recovery of DCE
sol vent and t o generat e t he necessary dat a f or
reduci ng t he consumpt i on of sodi um sul phi t e i n
mult i st age count er current ext ract ion syst em. The
d at a f r om t hese exp er i ment s w i l l b e usef ul i n
improving t he economics of t he process. The pilot
pl ant was successf ul l y demonst rat ed, guarant ee
runs were complet ed. The product from t he pilot
p l ant f ound t o meet al l t he sp eci f i cat i ons. The
reparat ion of DPR for 10000 TPA commercial plant
is in progress for evaluat ion of economic feasibilit y
for cont inuous as well as bat ch process. Sponsored
by M/ s Solaris Chemicals Lt d, Kar war, Karnat aka
O Nat ural Product s Ext ract ion Pilot plant :
Thi s p r oj ect i s ai med at st andar di zat i on of t he
process and set t ing up of t he solid liquid ext ract ion
syst em facilit y at Aryavaidyasala, Kot t akkal as a part
of t he on going DST-IICT-AVS j oint program. A five-
st ag e co u n t er cu r r en t co n t i n u o u s ext r act i o n
syst em i s d esi g ned , f ab r i cat ed and er ect ed at
Aryavaidyasala, Kot akkal. Mechanical commission-
ing was complet ed successfully. Experiment s were
conduct ed t o opt imize t he process paramet ers viz,
t ime of ext ract ion, t emperat ure, and part icle size,
wat er t o solid rat io.
O OO OO Process Improvement for Aspirin Plant of
M/ s Andhra Sugars Limit ed, Tanuku, AP
Present ly M/ s Andhra Sugars are manufact uring Aspirin,
a basi c drug and export i ng as per FDA regul at i ons of
USA. However, t he consumpt i on of r aw mat er i al s i s
observed t o be on t he higher side, when compared wit h
t he Int ernat ional Manufact uring Pract ices. IICT t aken up
t h e assi g n men t f o r l o o ki n g i n t o t h e p r o cess/
manufact uring det ails and workout met hodologies t o
i mprove t he conversi ons/ yi el ds/ recover y, f i rst i n t he
l aborat or y l evel . The pi l ot l evel experi ment s shal l be
co n d u ct ed at An d h r a Su g ar s Li mi t ed an d f i n al l y
i mp l emen t ed i n t h e co mmer ci al p l an t , u n d er t h e
g u i d an ce/ co n su l t an cy o f IICT. IICT co mp l et ed t h e
laborat ory experiment s successfully and designs of pilot
plant equipment is in progress.
* PROCESS MODELLING AND SIMULATION
IICT has been act i ve i n t he area of process model i ng
and simulat ion of chemical process plant s for t he last
t wo and hal f decades. The i nst i t ut e has under t aken
several process i mprovement opt i mi zat i on st udi es of
ch emi cal p r o cess p l an t s t h r o u g h mo d el i n g an d
si mul at i on and d evel op ment of si mul at i on/ d esi g n
soft ware for vari ous uni t operat i ons.
O OO OO Design and Supply of Gas Cracker Pilot Plant
This proj ect has been awarded by M/ s Gas Aut horit y of
Indi a Lt d., (GAIL) f or t he Desi gn and Suppl y of Gas
Cracker Pi l ot Pl ant of 5 kg/ hr cap aci t y f or t hermal
cr acki n g of et h an e or et h an e/ p r op an e mi xt ur e t o
et hyl ene. Fl ow sheet f or t he pi l ot pl ant i s devel oped
GAIL Pilot Plant
80
and t he equi pment such as t he f urnace, react or coi l s
heat exchangers are desi gned al ong wi t h t he pi pi ng
and inst rument at ion. The t ender document for t he skid
mount ed pi l ot pl ant i s prepared, and t he cont ract for
t he fabri cat i on, suppl y and erect i on of t he pi l ot pl ant
has been awarded t o M/ s Xyt el India Pvt . Lt d. Suit able
onl i ne gas anal yzers f or product gas anal ysi s duri ng
cracki ng and decoki ng are procured. Ri sk anal ysi s of
t his pilot plant is done t o ident ify hazards and suit able
d esi g n mo d i f i cat i on s ar e mad e. Th e p i l ot p l an t i s
cont rolled by a PC/ PLC syst em. The pilot plant is erect ed
and commissioned and it is working sat isfact orily. This
is a first of it s kind assignment under t aken by IICT.
* PROCESS SAFETY CENTRE
Th e Pr o cess Saf et y Cen t r e (PROSAC) d evel o p ed
exp er t i se i n t h e ar eas o f Hazar d an al ysi s, Ri sk
assessmen t an d Di sast er man ag emen t p r o g r ams.
PROSAC of f ers i t s exp ert i se and servi ces t o vari ous
chemi cal , pet rochemi cal and agrochemi cal i ndust ri es.
The chemical plant indust rial act ivit ies associat ed wit h
processi ng, st orage and t ransport at i on of hazardous
chemi cal s where fi re, expl osi on and t oxi c hazards are
likely t o t ake place and reasonable risk t o societ y exist s
ar e st u d i ed i n d et ai l . Th e p r o j ect t aken u p an d
su ccessf u l l y co mp l et ed b y t h i s g r o u p i s g i ven i n
Annexure.
IICT Process Safet y Cent er is equipped wit h t he following
t est f aci l i t i es and provi des t echnol ogi cal servi ces on
payment basi s.
O OO OO Dust Explosion Tests
Laborat ory Apparat us of t he t ype KSEP 20L is used for
t he det erminat ion of Explosion Indices of Combust ible
Dust s and gases.
O OO OO Ignition Test for airborne Dust BAM-Oven
Th i s t est i s d esi g n ed t o d et er mi n e t h e i g n i t i o n
t emperat ure of airborne dust on a hot surface (e.g. spray
dri er)
O OO OO Test for Exothermic Reaction in an open cup
Lutolf Oven Type MP-4
Th i s t est i s d esi g n ed t o d et er mi n e t h e l o w est
t emperat ure at which a subst ance shows an exot hermic
react i on under def i ned oxygen-l ean condi t i ons. Wi t h
t his t est , t he maximum permissible t emperat ure of t he
heat ing medium can be derived.
O TRAINING PROGRAMMES IN PROSAC
PROSAC i s or gani zi ng t he t r ai ni ng p r ogr ammes t o
various chemical and pet rochemical indust ries in t he
f i el d of Saf et y, Hazard and Ri sk anal ysi s. The Process
Saf et y Cent re successf ul l y compl et ed more t han 100
Hazard Anal ysi s and Ri sk Assessment assi gnment i n
2003-2005 period. In addit ion about 40 t o 50 samples of
vari ous chemi cal s were anal yzed f or t he hazardous
propert ies, such as flash point s, flammable limit s, aut o
ignit ion, t emperat ures and pressure waves generat ed
when explosion t akes place.
Present l y Process Saf et y Cent re i s j oi nt l y worki ng i n
collaborat ion wit h Inst it ut e of Engineering and Ocean
Technology (IEOT) ONGC for t hree assignment s relat ed
t o sof t wave and dat a-base development . They are:
1. Reliabilit y of safet y syst em in Off-shore plat form.
2. Failure frequency dat a base.
3. Toxi c gas di sp ersi on model s f or of f -shore pl ant
f orms
The nat ure of work i s undert aken f i rst of i t s ki nd i n
India and Int ernat ional applicat ion, specially in t he Off-
shore operat ions is expect ed.
A view of ONGC off-shore platform
81
*APPLIED RESEARCH
O Det ailed Engineering Designs f or pilot
plants
For Ni t rat i on of Tol uene for M/ s Vasant Chemi cal s Lt d
an d M/ s Deep ak Ni t r at es; Pyr azi n ami d e f o r SPIC;
Benzaldehyde for Vinat i Organics Lt d; HFC-134a for M/ s
Navi n Fl our i nes; TBBA f or M./ s BILT Chemi cal s Lt d,
Hyderabad; RWOOD Pilot Plant for RRL-Bhopal includes
engi neeri ng support i n f orm of desi gns, i nspect i on,
t est i ng and commi ssi oni ng of equi pment and rel at ed
machinery; Base Frame and Machine Mount ed t urbine
and compressor pi pi ng 3D l ayout s consul t ancy work
carried out for BHEL, Hyderabad. Set t ing-up of a pilot
an d t est i n g f aci l i t y f o r p r ep ar i n g an d t est i n g o f
l ubri cant s for avi at i on i ndust ry
O OO OO Det ail Engineering Design for Commercial
Plants
The process know-how f or t he ext ract i on of nat ural
col or s f r om t ur mer i c; ch i l l i an d an n at o seed s w as
d evel o p ed an d d emo n st r at ed b y Cen t r al Fo o d
Tech n o l o g i cal Resear ch In st i t u t e (CFTRI), Myso r e.
Det ai l ed En g i n eer i n g Desi g n s f o r t h e i n t eg r at ed
commercial plant were provided by IICT. The int egrat ed
co mmer ci al p l an t i s d esi g n ed t o h ave al l t h e
infrast ruct ure facilit ies for processing of 1.0TPD of raw
mat erial t urmeric, chilli and annat o separat ely in t hree
different sect ions at same t ime.
O Safety Assignments with PROSAC
O OO OO St udi es on Vul nerabi l i t y and Ri sk Assessment of
Tr ansp or t at i on of hazar dous sub st ances i n t he
St at e of Andhra Pradesh - A survey was done on
NH9 &7 t o acquire informat ion relat ed t o accident s
i nvol vi ng t ankers carryi ng hazardous chemi cal s
and t o col l ect i nf ormat i on on t he i nf rast ruct ure
facilit ies available. The dat abase was fur t her used
in carrying out t he QRA st udies.
O OO OO HAZOP st udi es were carri ed out f or Rayal seema
Alkalis Plant Complex, Kurnool; But adiene st orage
facilit y and React or for M/ s Andhra Sugars Pvt Lt d.,
Tanuku; UDMH p r ocess f or M/ s And hr a Sugar s
Li mi t ed, Tanuku; St orage f aci l i t y of POL product s
and pi pel i ne Transpor t POL product s by pi pel i ne
f r om Mang al or e r ef i ner y t o Bang al or e f or M/ s
PETRONET, Mangalore
O OO OO Safet y Audit was carried out for M/ s RALCHEM Pvt
Lt d , Hyd er ab ad ; Rayal seema Al kal i s and al l i ed
Chemicals Plant Complex, Kurnool and Cherlapally
POL Product s Depot , Hyderabad
O OO OO Quant i t at i ve Ri sk Assessment st udi es of t he f i el d
r ooms f or M/ s HPCL Ref i n er y Vi sak h ap at n am-
What -i f Anal ysi s was carri ed out f or PRU, DHDS,
Hydrogen st orage and SRU f aci l i t i es t o i dent i f y
hazards associat ed in t he process. As part of QRA
st udy f or f i el d rooms most credi bl e hazardous
scenar i os w er e i d ent i f i ed i n al l t he f our uni t s.
MECHANICAL DESIGN AND ENGINEERING MECHANICAL DESIGN AND ENGINEERING MECHANICAL DESIGN AND ENGINEERING MECHANICAL DESIGN AND ENGINEERING MECHANICAL DESIGN AND ENGINEERING
Natural Color Extraction Plant for M/s KCP Biotech Private Limited, Hyderabad
82
Co n seq u en ce an al ysi s an d d et er mi n at i o n o f
individual and societ al risk values were found out .
O OO OO Development of failure frequency dat abase: for M/
s Inst i t ut e of Engi neeri ng and Ocean Technol ogy,
Mumbai .
* Rain Erosion Facilit y
O The rain erosion t est rig set up is t he first of it s kind
i n t h e co u n t r y t o t est t h e r ai n er o si o n
charact erist ics of paint s developed and applied on
t he hi gh sp eed rot or bl ades of t he ai rcraf t . The
paint s such as for t he wings / blade of aircraft have
t o conform t o int ernat ional st andards such as MIL-
C-83231A. Hence i t i s mand at or y f or t he p ai nt
manuf act urers t o get erosi on t est cl earance f or
t heir paint s by well-est ablished cert ifying agencies.
Th i s r ai n er o si o n t est h as t o b e i n var i ab l y
conduct ed bef ore t he wel l -est abl i shed qual i f yi ng
& Cert ifying agencies of t he Minist ry of Defence like
M/ s RCMA, Hyderabad. Consi deri ng t he nat i onal
i mport ance i n devel opi ng a sui t abl e rai n erosi on
r esi st an t p ai n t man y cl i en t s b ot h p r i vat e an d
government i ncl udi ng def ense agenci es such as
KCMA, Hyderabad t est ed t he paint s.
O OO OO The paint samples are t o be evaluat ed for 1" Rainfall
condit ions wit h 2mm diamet er rain droplet s falling
cont inuously on t he paint samples and when t he
p ai nt samp l es are sub j ect ed t o sust ai ned wi nd
simulat ion speed of 500 miles per hour. Present ly,
t he t est ri g has achi eved 350 mi l e per hour wi nd
si mul at i on at 1r ai n f al l con d i t i on s w i t h 2 mm
droplet s. The t est rig is successfully demonst rat ed
t o t he i nspect i ng agenci es of M/ s Aeronaut i cal
Development Agency, Bangalore.
Number of IICT pai nt sampl es were t est ed and pai nt s
wit h bet t er rain erosion qualit ies have been developed.
The t est Ri g was al so successf ul l y demonst rat ed t o
evaluat e t he rain erosion charact erist ics of indigenous
p ai n t s d evel o p ed b y p r i vat e an d d ef en se cl i en t s
recent l y.
* DESIGN OF SPECIAL EQUIPMENT
O Rot a Disc Dryer/ Cooler Special Equipment
O OO OO The equi pment consi st s of a cent ral y mount ed
rot at ing screw t ype mechanism wit h many screw
t ype leaves arranged in concent ric fashion wit h a
p r o vi si o n t o ci r cu l at e f l u i d s t h r o u g h i n n er
p er i p h er y o f t h e scr ew t yp e mech an i sm.Th e
roat ing screw mechanism is also provided wit h a
fluid circulat ing j acket .The process solids while in
t he screw are being pushed forward by means of
p usher s cl amp ed t o t he i nd i vi d ual scr ew t yp e
leaves while hot / cold fluid is circulat ed in t he inner
and out er j ackect of t he screw t ype mechanism t o
enabl e t he process sol i ds t o be heat ed / cool ed
while being processed in t he unit .
O OO OO The screw t ype mechani sm assembl y i s powered
by means of an elect rical 3HP mot or provided wit h
a hand operat ed variable speed mechanism drive
t o enable t o increase/ reduce t he speed of t he screw
t yp e mech an i sm.Ro t ar y f l u i d j o i n t s h el p i n
successf ul l y ci rcul at i ng f l ui ds f rom t he st at i onary
pipe t o t he const ant ly rot at ing inner j acket of screw
t ype mechanism. The unit can be ideally operat ed
f or process sol i ds heat i ng , cool i ng and dryi ng
Paint testing Unit
83
op er at i on s. Th i s can al so b e used f or t h er mal
st abilisat ion of Rice-Bran
Project planning activity
Proj ect Pl anni ng and moni t ori ng act i vi t y was carri ed
for a number of proj ect s by using a met hod called ZOPP,
which st ands for Obj ect ives Orient ed Proj ect Planning.
This met hod emphasizes part icipat ion of all concerned
agencies t o evolve in det ail, a proj ect planning mat rix
(PPM) followed by a comprehensive plan of operat ions
(POP), which is t he micro schedule of t he proj ect . This
i s f ol l owed by a det ai l ed met hod of moni t ori ng and
evaluat ion of t he process of t he proj ect .
The p roj ect p l anni ng usi ng t he ab ove met hod was
carried out for t he following proj ect s
O OO OO A mult i-inst it ut ional proj ect NINE plus t hat st ands
for NGRI, IICT, NRSA, EPTRI and ot her agencies. This
proj ect ai ms t o st udy t he Carr yi ng Capaci t y, of
Vi sakhapat nam regi on.
O OO OO Bi ot echnol ogy i ncub at i on cent er (BTIC) p roj ect
ai ms t o est ab l i sh a st at e of t h e ar t f aci l i t y f or
incubat ing biot echnologies and t o provide world-
class facilit ies t o different client s and designing t o
upscale t heir bioprocesses.
* BASIC RESEARCH
O OO OO Simulat ion and modeling t hrough virt ual
realit y wit h special emphasis on chemical
lab safet y and hazards
Most of t he acci dent s t hat occur i n chemi cal l ab and
chemi st ry are due t o l ack of knowl edge / pract i ce of
saf et y pr i nci pl es. Regul ar and peri odi cal Hands on
r ef r eshment t r ai ni ng cour se t o t he st af f i s l i kel y t o
reduce t hese accident s drast ically. However, organizing
t raining programs can be t edious and t ime consuming
and exp ensi ve t o t he or gani zat i ons / Inst i t ut i ons /
Indust r y.
Use of comput eri zed Vi r t ual Real i t y (VR) i mmersi ons
can come t o t he rescue of t hi s si t uat i on t hrough t he
development of t raining simulat ors. Virt ual Realit y (VR)
i s cut t i n g ed g e t ech n ol og y t h at al l ow s us t o st ep
t hrough t he comput er screen int o a t hree dimensional,
i nt er act i ve envi ronment . Vi r t ual Real i t y provi des an
opport unit y t o t he user t o get immersed t ot ally in t he
required / suit able scenario and offer spont aneous reflex
act i ons t o t he comp ut er si mul at ed scenes. Besi des
g r ap hi c scenes t hr oug h sui t ab l e d i sp l ay d evi ces a
p hysi cal i n t er f ace i s p ossi b l e i n VR t o r ep r esen t /
simulat e physical reflexes of users.
O OO OO Transverse vibrat ions of mult iply bellows
expansi on j oi nt el ast i cal l y r est r ai ned
against rotation
Dynami c aspect s of si ngl e and mul t i pl y bel l ows wi t h
el ast i cal l y rest rai ned ends and under rot at ory i nert i a
were st udi ed. The ef f ect of r ot at i onal r est rai nt s and
int ernal pressure loading on response of such bellows
configurat ion is at t empt ed. The exact coupled response
obt ained is compared wit h previous works. Two cases
ar e consi d er ed - b el l ows havi ng same mat er i al and
different mat erials for plies. An at t empt has been made
t o derive and est ablish expressions t hat are simple and
compat i bl e i n comput i ng t he nat ural f requency and
mo d e sh ap es of b el l o w s. Th e Rayl ei g h Qu ot i en t
met hod i s al so used for t hi s purpose. (Journal of Thi n
Wal l ed St ruct ures, 42(2004) 415-426, El sevi er Appl i ed
Science Publishers, Great Brit ain)
Mechanical Design and Engineering
84
The IICT Comp ut er Cent r e und er t akes ap p l i cat i on
soft ware development in areas of scient ific import ance
t o i n st i t u t i o n al r esear ch p r o g r ammes, b esi d es
provi di ng sci ent i f i c i nput s based on comput er ai ded
t echni ques t o ongoi ng R&D proj ect s and conduct i ng
t r ai n i n g p r o g r ammes i n ad van ced co mp u t er
programmi ng.
O Ranking of Indian Coals by Fuzzy Mult i
Attribute Decision Making(FMADM)
Co al r an ki n g p r o b l em i s mo d el ed as f u zzy mu l t i
at t ribut e decision making problem. Proximat e analysis
of coal is t aken as basis. Saat y Analyt ic Hierarchy Process
(AHP) was empl oyed t o come out wi t h i mport ance
rat i ngs for 4 coal qual i t y vari abl es vi z. Fi xed Carbon,
Volat ile Mat t er Moist ure Cont ent & Ash Cont ent . Then
modi f i ed Yager s FMADM model i s i nvoked t o come
out wi t h rat i ngs f or di f f erent cooki ng & non-cooki ng
coalfields in India. The st udy was conduct ed for t hree
memb er sh i p s f u n ct i o n s an d 4 ag g r eg at o r s. In
conclusions, t he modified FMADM model yielded bet t er
rat i ngs f or coal f i el ds t han t he ones gi ven by f act or
anal ysi s st udy.
O Fuzzy Rul e Based Cl assi f i cat i on wi t h
Feat ure Select or and Modified Threshold
Accepting
Thi s st udy hi ghl i ght s t he paramount i mport ance of
f eat ure sel ect i on i n t he cont ext of f uzzy rul e based
cl assi f i cat i ons. Feat ure sel ect i on i s t aken care of by a
soft ware Feat ure Select or. Then t he modified fuzzy rule
based classifier is developed and invoked for classificat -
i o n t ask. Lat er t h e mo d i f i ed t h r esh o l d accep t i n g
algorit hm is developed and invoked t o solve t he result -
i n g co mb i n at o r i al o p t i mi zat i o n p r o b l em w i t h 2
obj ect i ve f unct i ons t o maxi mi ze cl assi f i cat i on power
and t o minimize t he size of t he rule base. The efficacy of
t he model is demonst rat ed on wine classificat ion and
Wi sconsi n breast cancer probl ems yi el di ng very good
resul t s.
O Principal Component Analysis and Fuzzy
Rule Based Classification.
For t he f i rst t i me, Pri nci pal Component Anal ysi s was
combined wit h fuzzy rule based classificat ion. PCA was
used a feat ure select ing module. Then t he modified fuzzy
rule based classifier invoked. The ent ire sof t ware is t est ed
for i t s ef f i cacy on wi ne and Wi sconsi n breast cancer
problems yielding good result s.
O Fuzzy Global Opt imizat ion of Complex
System Reliability
The opt imizat ion problem of complex syst em reliabilit y
is modeled in a fuzzy environment . The result ing crisp
versions are solved by t hreshold accept ing algorit hm.
Th e st u d y i s co n d u ct ed f o r 6 d i f f er en t t yp es o f
aggregat ors. The st udy yielded more efficient solut ions
compared t o t he ones conduct ed in t he single obj ect ive
envi ronment .
O Prediction of Treatment Concentrations for
t he Reduct ion of COD of t he Effluent s of
Pesticide Plant by LOGIT Models.
The necessi t y of reduci ng t he COD cont ent s of t he
ef f l uent s of t he pest i ci de pl ant t o accept abl e l i mi t s
bef ore rel easi ng i t t o t he envi ronment i s very much
essent ial. Treat ment met hods for reducing COD values
are developed and t he reduced COD values for various
concent rat i ons of act i vat ed coconut shel l (ACC) are
eval uat ed exp er i ment al l y. A novel st at i st i cal model
cal l ed l ogi t model i s devel oped f or est abl i shi ng t he
r el at i o n sh i p b et w een ACC co n cen t r at i o n s an d
percent age COD reduct i on. The model was f ound t o
g i ve ver y accu r at e r esu l t s f o r p r ed i ct i n g ACC
concent rat ion requirement s for t he reduct ion of COD
values by 50,60,70,80,90,95 and even 99% of t he original
COD values.
O Correl at i ons Among Physi co-Chemi cal
Properties of Effluents of Various Chemical
Process Indust ries.
Ver y good correl at i ons were ob ser ved among t he
p h ysi co-ch emi cal p r op er t i es l i ke p H, con d uct i vi t y
(COND), Tot al Di ssol ved Sol i ds ( TDS), and Chemi cal
COMPUTER CENTRE COMPUTER CENTRE COMPUTER CENTRE COMPUTER CENTRE COMPUTER CENTRE
85
Oxygen Demand (COD) f or t he ef f l uent s of vari ous
chemical process indust ries and IICT processes. These
cor r el at i ons ar e ver y hel p f ul i n und er st and i ng t he
associ at i ons among t he physi co-chemi cal propert i es
of effluent s. Also, good predict ion equat ions have been
developed for predict ing COD in t erms of pH, COD and
TDS.
O Software Development
Several web sit es were developed for various seminars
and MIS Applicat ions.
O Data Mining
A pilot st udy was carried out successfully for t he dat a
sup p l i ed by M/ s Sat yam Comp ut er s Lt d. The dat a
p er t ai n i n g t o CD b u yer s i n f o r mat i o n l i ke ag e,
educat ion, occupat ion, race, relat ion, sex, working class,
marit al st at us, et c. was analyzed. The obj ect ive of t his
st udy was: 1) t o devel op a predi ct i ve model f or t he
above dat a (ii) t o ident ify t he pot ent ial CD buyers. The
d at a mi n i n g t ech n i q u es l i ke f u zzy r u l e b ased
cl assi f i cat i on, neural net s and mul t i vari at e st at i st i cal
models, were applied t o analyze t he dat a.
The Comput er Cent re has developed new expert ise in
t he following mult i disciplinary area:
Fuzzy Comput i ng
Fuzzy cl ust er anal ysi s, Fuzzy rul e based syst ems
for pat t ern classificat ion
Neuro Comput i ng
ANN & i t s var i an t s f o r f o r ecast i n g & p at t er n
classificat ion, neuro-fuzzy hybrids
Evol ut i onary Comput i ng
Global opt imizat ion met a heurist ics, combinat orial
opt imizat ion, Mult i obj ect ive opt imizat ion.
St at ist ical Modelling
MLR Techni ques, Uni vari at e Met hods, Dat a Reduct i on
Techniques, Time Series Models, Pat t ern Ident ificat ion
and Cl ust eri ng.
Computer Centre
86
* * * * * BASIC RESEARCH
O OO OO Hydr ogen Pr oduct i on f r om Anaer obi c
Process
Bi o h yd r o g en p r o d u ct i o n t h r o u g h an aer o b i c
f er men t at i o n u si n g ch emi cal w ast ew at er w as
successf ul l y achi eved on a l ab scal e react or. React or
co n f i g u r at i o n , i n o cu l u m p r et r eat men t , st ar t u p
procedure, co-subst rat e addit ion, nut rient composit ion,
et c were opt imized for effect ive hydrogen product ion.
Suspended growt h and bi of i l m conf i gured syst ems
were designed and operat ed in periodic discont inuous
mode for t he product ion of hydrogen using composit e
chemical and bulk drug wast ewat er. By way of process
opt imizat ion, effect ive hydrogen yield was achieved in
b o t h t h e co n f i g u r ed syst ems h o w ever, b i o f i l m
conf i gured syst em showed superi or perf ormance.
O OO OO Anaer obi c Pr ocess Opt i mi zat i on by
Dynamic Taguchi DOE Methodology
Taguchi robust experiment al design met hodology was
applied on dynamic anaerobic process t reat ing complex
wast ewat er by anaerobi c sequenci ng bat ch bi of i l m
react or (AnSBBR). For opt i mi zi ng t he process and t o
evaluat e t he influence of different fact ors on t he process
t he uncont rol l ab l e (noi se) f act ors were consi dered.
Taguchi met hodol ogy adopt i ng dynami c approach i s
applied for t he first t ime for st udying anaerobic process
eval u at i o n an d p r o cess o p t i mi zat i o n . In t h e
experiment al design, five cont rollable fact ors i.e., organic
loading rat e (OLR), inlet pH, biodegradabilit y (BOD/ COD
rat i o), t emperat ure and sul f at e concent rat i on, al ong
wit h t he t wo uncont rollable (noise) fact ors viz., volat ile
f at t y aci d s ( VFA) an d al k al i n i t y at t wo l evel s wer e
consi dered f or opt i mi zat i on of t he anaerobi c syst em.
Thirt y t wo anaerobic experiment s were conduct ed wit h
d i f f er en t co mb i n at i o n o f f act o r s an d t h e r esu l t s
obt ained in t erms of subst rat e degradat ion rat es were
processed i n Qual i t ek-4 sof t ware t o st udy t he mai n
ef f ect of i ndi vi dual f act ors, i nt eract i on bet ween t he
i ndi vi dual f act ors, si gnal t o noi se (S/ N) rat i o anal ysi s
an d f i n al l y, at t emp t s wer e mad e t o ach i eve t h e
o p t i mu m co n d i t i o n s. Co n si d er i n g t h e o b t ai n ed
opt i mum fact ors, furt her val i dat i on experi ment s were
car r i ed o u t , w h i ch sh o w ed en h an ced p r o cess
performance (3.04 Kg COD/ m
3
-day from 1.99 Kg COD/
m
3
-day) account ing for 52.13% improvement wit h t he
opt i mi zed process condi t i ons. The proposed met hod
f aci l i t at ed a syst emat i c mat hemat i cal ap p r oach t o
und er st and t he comp l ex mul t i -sp eci es mani f est ed
an aer o b i c p r o cess t r eat i n g co mp l ex ch emi cal
wast ewat er by considering t he uncont rollable fact ors.
O OO OO Production of Enzymes
Laccase Pr o d u ct i o n b y su b mer g ed f er men t at i o n :
Product i on of l accase usi ng pl eurot us ost reaus 1804
was st udi ed under vari ous experi ment al condi t i ons.
Among t he carbon sources st udi ed, gl ucose resul t ed
i n hi gher l accase yi el d whereas dext ran and gl ycerol
suppl ement ed brot h showed rel at i vel y l ess l accase
induct ion. In immobilized mycelia influence of various
paramet ers on laccase expression was also examined.
It is evident from t he st udy t hat t he cult ure condit ions
st udied viz., biomass level, pH, subst rat e concent rat ion,
Evaluating treatment of Industrial Wastewater by Lab Designed
and Fabricated reactor
Biohydrogen Production by Lab Designed and Fabricated Reactor
BIOENGINEERING AND ENVIRONMENTAL CENTRE BIOENGINEERING AND ENVIRONMENTAL CENTRE BIOENGINEERING AND ENVIRONMENTAL CENTRE BIOENGINEERING AND ENVIRONMENTAL CENTRE BIOENGINEERING AND ENVIRONMENTAL CENTRE
87
yeast ext ract concent rat i on, Cu
+2
concent rat i on and
nat ure of alcohol showed significant influence on t he
laccase yield. Enhanced laccase yield was also evidenced
due t o immobilizat ion.
O OO OO Different Immobilization Matrices for Lactic
Acid Production
Di f f er en t p o l ymer mat r i ces w er e p r ep ar ed f o r
i mmob i l i zat i on st ud i es f or l act i c aci d p r od uct i on .
Evaluat ion of t he mat rices was carried out . The mat rix
showed higher bact erial cell loading, higher product ivit y
and higher st abilit y under acidic pH condit ions.
O OO OO Bioaugmentation
Bioaugment at ion st rat egy by augment ing immobilized
sul fat e reduci ng bact eri a (SRB) i n pol ymer mat ri x was
successf ul l y appl i ed f or enhanci ng anaerobi c process
efficiency t reat ed sulphat e bearing composit e chemical
wast ewat er. Bioaugment at ion t echnique was also used
successf ul l y b y i nocul at i ng wi t h ETP mi cr of l or a f or
enhanci ng degradat i on abi l i t y of nat i ve mi crof l ora i n
b i o-sl ur r y p hase r eact or i n t he p r ocess of t r eat i ng
pendi met hal i n cont ami nat ed soi l .
O OO OO Laccase Production optimization by Taguchi
orthogonal OA approach
The ap p l i cat i on of a st at i st i cal met hod ol ogy usi ng
d esi g n o f exp er i men t al (DOE) ap p r o ach f o r t h e
opt imizat ion of cult ure condit ions of laccase product ion
by SMF. Sub mer ged cul t ur e cond i t i ons f or l acasse
p r od uct i on b y P. ost r eat us 1840 w as op t i mi zed b y
employing Taguchi ort hogonal array (OA) experiment al
desi gn (DOE) approach. The obt ai ned opt i mal cul t ure
condit ion for t he laccase product ion from t he proposed
met h o d o l o g y w as val i d at ed b y p er f o r mi n g t h e
exp er i men t s w i t h t h e o b t ai n ed co n d i t i o n s. Th i s
approach al so faci l i t at ed t he st udy of i nt eract i on of a
l ar g e numb er of var i ab l es w i t h a smal l numb er of
designed experiment al region spanned by fact ors and
t hei r set t i ngs l eadi ng t o consi derabl e savi ng i n t i me
an d co st f o r t h e p r o cess o p t i mi zat i o n . Tag u ch i
experi ment al desi gn resul t ed i n eval uat i ng t he mai n
an d i n t er act i o n ef f ect s o f t h e sel ect ed f act o r s
i n d i vi d ual l y an d i n comb i n at i on i n t h e p r ocess of
enzyme synt hesi s. Thi s met hodol ogy al so f aci l i t at ed
analysis of t he result ing experiment al dat a t o est ablish
t he opt imum condit ions for t he process, est ablish t he
cont ri but i on of i ndi vi dual fact ors and t o est abl i sh t he
response under opt imal condit ions.
* * * * *APPLIED RESEARCH
O OO OO Development of Pilot Level Anaerobic Reactor for
Pharmaceut ical Wast e : The IICT has under t aken t hi s
proj ect under PATSER programme from DSIR for NATCO
Pharma, Hyderabad. Ext ensive laborat ory experiment s
were conduct ed and process variables were opt imized
in t he laborat ory. 2.5m
3
pilot scale anaerobic fixed bed
react or was desi gned i nst al l ed and commi ssi oned at
t he indust ry t o generat e in-sit u dat a for scale up. Pilot
Pl ant exp er i ment s wer e successf ul l y cond uct ed t o
opt i mi ze t he process vari abl es. Frequent changes i n
product prof i l e of modern pharmaceut i cal i ndust ry
usually result s in change of wast e wat er charact erist ics.
St able react or performance was achieved by following
sp eci al l y p r o g r ammed p r o t o co l s f o r mai n t ai n i n g
suit able consort ia t hat can absorb shock loads due t o
changi ng wast ewat er charact eri st i cs. The t echnol ogy
is proved t o be a feasible and at t ract ive opt ion for t he
t r eat ment of r ecal ci t r ant wast ewat er b y an ener gy
efficient syst em.
O OO OO Treat ment of effluent s from CETP : An upf l ow
anaerobic sludge blanket react or (UASB) was fabricat ed
i n t he l ab orat or y. Treat ment of comp osi t e chemi cal
wast ewat er havi ng hi gh sul phat e cont ent and l ow-
Bioengineering and Environmental Centre
1.5 letre Microbial Fermentor (B.Braun)
88
b i o d eg r ad ab i l i t y w as su ccessf u l l y d evel o p ed an d
demonst rat ed t o M/ s. Pat ancheru Efflulent Treat ment
Plant in a laborat ory st udies scaled UASB react or. Also,
UASB syst em int egrat ed wit h ASP and air st ripper t o
su p p r ess t h e su l p h i d e i n h i b i t i o n w as al so
d emon st r at ed at l ab or at or y scal e. Th e i n t eg r at ed
t reat ment syst em wit h pilot scale facilit y was designed
and submit t ed.
O OO OO Enzyme Mediat ed Degradat ion : Transformat ion
o f xen o b i o t i c co mp o u n d s w i t h en zymes as a
pret reat ment opt i on t o enhance t he bi odegradabi l i t y
of wast ewat er was successfully achieved wit h free and
i mmobi l i zed f orm of enzymes. Lacasse and HRP were
used as oxidat ive enzymes in t he degradat ion st udies.
Degradat i on of azo dye and ant hracene was st udi ed
and very efficient degradat ion of azo dye and ant hrcene
was observed using t he enzymes.
O OO OO Development of High performance Biological
Fluidized Bed React or f or Ant ibiot ic Product ion :
Product ion of ant ibiot ics is one of t he import ant areas
of research in applied microbiology. A high per formance
b i ol ogi cal f l ui di zed b ed r eact or was devel op ed f or
an t i b i o t i c p r o d u ct i o n u si n g i mmo b i l i zed cel l s o f
St r ept omyces sp. DST awarded t hi s as a grant -i n-ai d
proj ect . Cont inuous fluidized bed react or was operat ed
aft er init ial opt imizat ion st udies involving pH, aerat ion,
ag i t at i o n , i mmo b i l i zat i o n mat r i ces, n u t r i en t
requi rement et c. f or t he product i on of st rept omyci n
an d o xyt et r acycl i n e. As p ar t o f b asi c r esear ch
component several new act inomycet e st rains also were
al so i sol at ed and t he compound charact eri zat i on was
est ablished which result ed in pat ent s and publicat ions.
O OO OO Periodic Discontinuous Process Development for
t heTreat ment of Complex Chemical Wast ewat er :
Periodic discont inuous process was successfully applied
for t he complex chemical wast ewat er t reat ment . Various
seq u en ci n g b at ch r eact o r (SBR) co n f i g u r at i o n s
(suspended/ bi of i l m/ f i xed bed/ i mmobi l i zed bed/ GAC
car r i er ) wer e st ud i ed and op t i mi zat i on al ong wi t h
var yi n g r eact o r mi cr o en vi r o n men t al co n d i t i o n s
(aerobic/ anoxic/ anaerobic) and phase variat ions (filling/
r eact i o n / set t l i n g / w i t h d r aw al ). Resu l t s sh o w ed
en h an ced p er f or man ce of p er i od i c d i scon t i n uous
p r ocess over t he cor r esp ond i ng cont i nuous mod e
operat i ng syst ems. Rapi d st art up phase, resi st ance t o
shock and t ransient loads, relat ively less HRT, flexibilit y
of car r yi ng al l uni t op er at i ons i n a si ngl e r eact or,
feasibilit y t o operat e at higher organic loading, flexibilit y
t o provide required redox condit ions, et c are some of
t he maj or advant ages of t he peri odi c di scont i nuous
operat ion. Biofilm configured syst ems showed effect ive
p er f or mance over al l ot her conf i gur at i ons st udi ed.
Aerobic met abolic funct ion provided effect ive subst rat e
yi el d. Incl usi on of anoxi c p hase i nb et ween aerob i c
met abolic funct ion showed t o have posit ive influence
on t he perf ormance. One pat ent was f i l ed on bi of i l m
con f i g ur ed seq uen ci n g b at ch r eact or op er at ed i n
peri odi c di scont i nuous process.
O OO OO Decont aminat ion of Soil by Bio-slurry Phase
React or : Bi o-sl u r r y syst em op er at i n g i n p er i od i c
d i sco n t i n u o u s o p er at i o n w as d evel o p ed f o r t h e
t r eat men t of con t ami nat ed soi l . The ab i l i t y of t he
react or was successfully st udied wit h chlorpyrifos, DEP
and pendimet halin cont aminat ed soil. The slurry phase
syst em showed enhanced degradat i on rat e over t he
co r r esp o n d i n g i n si t u syst ems. So i l w at er r at i o ,
subst rat e part i t i on, aqueous phase pH, co-subst rat e
addi t i on, sub st rat e sorp t i on mechani sm, met ab ol i c
pat hway elucidat ion was st udied.
O OO OO Cont ami nat ed Soi l Remedi at i on : Mer cu r y
moni t or i ng i n soi l mat r i x and wat er b od i es i n and
around a chemical fact ory was est imat ed along wit h it s
TCLP ch ar act er i st i cs. Remed i al measu r es w er e
suggest ed. Mercury anal ysi s was carri ed out at t race
levels in soil and wat er mat rices.
89
The Engineering Services Division cat ers t o t he needs
of all t he R&D Divisions and support ing services of t he
Inst it ut e by ensuring t he supply of ut ilit ies like power,
st eam, wat er, gas and manages refrigerat ion services. It
al so u n d er t akes f ab r i cat i o n o f sp eci al l y d esi g n ed
equipment for lab, bench scale st udies in R&D divisions
and pilot plant / up-scaling divisions. It also t akes charge
of i nst al l at i on and mai nt enance of ut i l i t y servi ce l i nes
i n t he l ab orat or y and p i l ot p l an t s. The Engi neeri ng
Ser vi ces Di vi si on has p ar t i ci p at ed i n t he f ol l owi ng
act ivit ies of t he laborat ory R&D proj ect s:
O OO OO Desi g n & d evel o p men t o f mo d er n w et
chemi cal l aborat ori es
O OO OO Er ect i o n & co mmi ssi o n i n g o f 500k VA
t ransformer, 11 kV VCB panel,
GENERAL ENGINEERING SERVICES GENERAL ENGINEERING SERVICES GENERAL ENGINEERING SERVICES GENERAL ENGINEERING SERVICES GENERAL ENGINEERING SERVICES
Autoclave designed by Nanomaterial group & fabricated
at the workshop
Rice bran stabilisation unit fabricated at the workshop
O OO OO Development of out door 11k V swit ching yard
O OO OO Design & Execut ion of elect rical power
O OO OO Li ght i ng di st ri but i on syst ems f or l aborat ory
R&D proj ect s
O OO OO Erect i on and commi ssi oni ng of Sebaci c aci d
react or
O OO OO Renderi ng S&T servi ces t o BHEL R&D Uni t i n
Moulali Complex on cont ract ual agreement
O OO OO Engineering support t o Pyrazinamide proj ect
O OO OO Par t i ci p at ed as t ech n i cal memb er f o r
inspect ion of equipment for degumming and
dewaxi ng of ri ce bran oi l (RBO) suppl i ed by
Proj ect Engineering Companies t o various RBO
Processing Indust ries across India under TMOP
grant -i n-ai d assi st ance proj ect .
90
The Pi l ot Pl ant f aci l i t y i s an essent i al i nf rast ruct ural
support for upscaling of laborat ory scale process for
t echnol ogy devel opment act i vi t y at IICT. The general
and mult ipurpose pilot plant s are basically ut ilised for
up scal i ng l ab or at or y knowhow p r i or t o t r ansf er t o
client s. A significant feat ure of t he upscaling act ivit y is
t he generat i on and col l ect i on of dat a f or basi c and
det ai l ed desi gn engi neer i ng. The pi l ot pl ant f aci l i t y
consi st s of equi pment f or a whol e spect rum of uni t
operat ions of chemical process indust ries. The facilit y
i s equi pped wi t h al l -gl ass, gl ass- gl ass-l i ned and S.S.
react or syst ems and all-glass dist illat ion columns wit h
cap aci t i es var yi n g f r o m 20 t o 200 l i t r es; r o t ar y
evaporat ors, dryers, sieve shakers of various capacit ies,
mixing unit s, spray dryers et c. At t imes modificat ions
t o exi st i ng uni t s are cal l ed f or t o sui t cert ai n speci al
p r ocess p ar amet er s and t hi s i s done wi t h i n-house
exp er t i se. Maki ng t he p i l ot p l ant cond uci ve t o t he
process operat i ons i s prerequi si t e f or any upscal i ng
st udy. Thi s f aci l i t y has been ext ensi vel y used duri ng
t h e r ep o r t i n g p er i o d f o r u p scal i n g / o p t i mi si n g
processes developed in all applied R&D area of research
at t he Inst it ut e.
The ot her component of t he upscal i ng f aci l i t y at IICT
comprises need based dedicat ed pilot plant s specifically
designed, fabricat ed and erect ed, most ly wit h inohouse
expert i se. Such f aci l i t i es are devel oped f or process
evaluat ion wit h respect t o it s feasibilit y and commercial
p l an t con d i t i on s f or t h e st ud i es. In var i ab l y t h i s i s
undert aken wi t h sponsorshi p f rom i ndust ry desi rous
of commerci al i si ng t he t echnol ogy. IICT has set up
dedi cat ed p i l ot p l ant s f or Mononi t r ot ol unes, TBBA,
Benzal dehyde et c.
* Disposal of Toxic Gases
IICT has p rovi ded t echni cal consul t ancy servi ces t o
Bharat Elect ronics Limit ed., Bangalore for disposing of
chemicals and t oxic gases such as Hcl and silane. IICT
also provided t raining t o BEL st aff for safet y procedures
for handling gas cylinders. Based on t his expert ise ot her
organisat ions approached IICT for similar services and
negot i at i ons are i n progress.
* Cane Bagasse Hydr ol ysi s and Al cohol
Fermentaion
IICT has provided pilot plant facilit ies and consult ancy
services for M/ s Reliance Life Sciences Pvt . Lt d., Mumbai
f o r co n d u ct i n g t r i al s f o r p r o d u ci n g al co h o l u si n g
bagasse hydrolysis. IICT modified t he IICT exist ing pilot
p l an t eq u i p men t t o su i t t h e p r o cess o p er at i n g
condit ions of Reliance for t rial runs. IICT scient ist s also
p art i ci p at ed i n t ri al runs and p rovi ded consul t ancy
servi ces f or upscal i ng of t he process. M/ s Rel i ance
approached IICT f or f urt her ut i l i zat i on of Pi l ot Pl ant
f aci l i t i es f or ot her product s based on t hi s experi ence.
IICT also provided pilot plant facilit ies t o out side part ies
on payment basis. Some of t hem are:
O OO OO E&M Chemicals Pvt . Lt d., Hyderabad
O OO OO AVRA Laborat ori es Pvt . Lt d., Hyderabad
O OO OO Saraca Laborat ories, Gaddapot haram, Medak Dt .
AP
O OO OO Vishnu Chemicals, Jeedimat la, Hyderabad
O OO OO Med ch al Ch emi cal s & Ph ar maceu t i cal s,
Hyderabad.
Some of t he maj or sponsored proj ect s ut ilized pilot plant
facilit ies are:
O OO OO Mononi t ro t ol uenes
O OO OO Esf enval erat e
O OO OO Pheromones
O OO OO Cast or oil based derivat ives
O OO OO Hydroxy et hyl cellulose
O OO OO Drug i nt ermedi at es
O OO OO Specialit y chemicals
O OO OO Degumming of rice bran oil
PILOT PLANT (UPSCALING) FACILITIES PILOT PLANT (UPSCALING) FACILITIES PILOT PLANT (UPSCALING) FACILITIES PILOT PLANT (UPSCALING) FACILITIES PILOT PLANT (UPSCALING) FACILITIES
All glass Pilot Plant unit for process upscaling
91
BUSINESS MANAGEMENT BUSINESS MANAGEMENT BUSINESS MANAGEMENT BUSINESS MANAGEMENT BUSINESS MANAGEMENT
Th e Bu si n ess Man ag emen t Di vi si o n co n t i n u ed t o
f u n ct i o n ef f ect i vel y w i t h t h e f o l l o w i n g b u si n ess
development and relat ed act ivit ies:
* BUSI NESS DEVELOPMENT ( NATI ONAL &
OVERSEAS)
O Bu si n ess Devel o p men t w i t h t h e ar ms f o r
l ooki ng af t er nat i onal and overseas busi ness
i nt erest s of t he organi zat i on.
O Publicit y including Publicat ions, Phot ography &
i nd ust r i al camp ai gns and i s r esp onsi b l e f or
proj ect i ng t he i mage of t he Inst i t ut e out si de,
which in t urn helps it s business int erest s.
Th i s Di vi si on i s w el l eq ui p p ed w i t h comp ut er i zed
informat ion, mult imedia and document at ion facilit ies.
It is in t ouch wit h past and present client s and helps in
providing cont ract research, consult ancy services and
t echni cal servi ces t o t he cl i ent s bot h overseas and
nat i onal i ndust r y.
It is in close t ouch wit h t he Indian Business Associat ions
like ICMA, IDMA, BDMA and FICCI. A special brochure
Port folio of IICT Technologies and Ser vices is brought
out every year and sent t o t he part i es keepi ng t hem
abreast wit h t he lat est t echnologies and services of t he
Inst i t ut e.
Fo r o ver seas b u si n ess i n t er est s, t h e Di vi si o n h as
est ab l i sh ed f o r mal l i n kag es w i t h t h e o ver seas
consult ing companies looking aft er it s int erest in USA
and Europe. Inst it ut e also part icipat es in maj or business
fairs and assemblies t o showcase it s capabilit ies in t he
field of chemical t echnology. During 2003-05, IICT has
ent ered int o cont ract wit h t he following maj or Indian
and overseas compani es:
Overseas
O Aisin Cosmos R&D Co. Lt d., Japan
O Glaxo Smit hkline Beecham, UK
O Confluent Surgicals, USA
O Givaudan, Swit zerland
O Dupont , USA
O Asian Adhesive Udyog Lt d., Nepal
O InnoCent ive, USA.
Nat i onal
O Neuland Labourat ories Lt d. Hyderabad
O Anus Labourat ories Lt d., Hyderabad
O Rajshree Sugars & Chemicals Lt d.,
Coimbat ore
O KCP Biot ech Lt d., Hyderabad
O DRDL, Hyderabad
O Navine Flourine Indust ries Lt d., Mumbai
O Tripura Biot ech Lt d., Hyderabad
O Cent ral India Lt d., Ghaziabad
O Indus Biosciences Pvt . Lt d., Hyderabad
O Sai Life Sciences Lt d., Hyderabad
O USV Lt d., Mumbai
O Max Bond, Bangalore
O Balmer & Lawrie Co. Lt d., Chennai
O Ashian Herbex Lt d., Chennai
O Alchem Int ernat ional Lt d., New Delhi and
Bangal ore
92
Signing of agreement with Inno Centive, USA
Signing of agreement with Asian Adhesive Udyog Ltd., Nepal Signing of agreement with M/S SMS Pharmaceuticales
DST / IICT / Dabur Drug Programme Initiation
Exchange of agreements with M/S Indo - Swift Ltd.,
93
In addi t i on, t he f ol l owi ng i ni t i at i ves were t aken f or
growt h in cont act wit h out side agencies:
O OO OO Overseas business delegat ions were invit ed t o
vi si t IICT t aki ng i n vi ew t hei r st rengt hs and
weaknesses in chemical research compared t o
IICT.
O OO OO Web based cont act s were made wi t h buyers
int erest s in chemical research.
IICT Web si t e w as mad e mo r e vi b r an t w i t h t h e
i n t r o d u ct i o n o f Bu si n ess Man ag emen t act i vi t y as
separat e f ol der.
Di st i ngui shed vi si t ors f or b usi ness are gi ven i n t he
Annexure :
* PUBLICATIONS
Busi ness Management Di vi si on pl ayed proact i ve rol e
i n t he publ i cat i ons and phot ography act i vi t i es. Maj or
publicat ions brought out during t he report ing period
are given below:
- IICT Bullet in, April 2001 March 2003
- Diamond Jubilee Book, IICT 60 Years of Service t o
t he Nat i on
- Pouch Folder & Leaflet s on IICT Act ivit ies
- Br o ch u r e: Po r t f o l i o o f IICT Tech n o l o g i es an d
Servi ces
Business Management
94
* INDUSTRIAL CAMPAIGNS & SEMINARS
Business Management Division act ively part icipat ed as
organi si ng commi t t ee member, i n organi si ng t he IICT
Di amo n d Ju b i l ee Cel eb r at i o n s w h i ch i n cl u d ed
i mp o r t an t semi n ar s, w o r ksh o p s, memo r i al
t ournament s & l ect ures, et c., Det ai l s are gi ven i n t he
Diamond Jubilee Chapt er separat ely.
The inst it ut e also part icipat ed in a number of Indust rial
Camp ai g n s t o p u b l i ci se i t s R&D act i vi t i es an d
achievement s made. Some of t hese are:
O India Composit e Seminar-cum Exhibit ion (Oct .
2003), Hyderabad.
O Indian Int ernat ional Trade Fair (Nov 14-29, 2003),
New Delhi
O Pharma Expo-2003 (Dec 19-21, 2003), Chennai
O Save En er g y Exh i b i t i o n (Feb 17-19, 2004),
Inst it ut ion of Engineers, Hyderabad
O India Composit e Expo-2005 (Feb. 25-26, 2005),
Hyderabad
* PHOTOGRAPHIC SERVICES
IICT has developed expert ise in scient ific phot ography
needed for R&D proj ect s. Business Management Division
has provided phot ographic input s t o X-ray, biology and
t oxicology proj ect s. Phot ographs given below are t aken
by digit al camera and comput er:
(a) Pu r i t y o f si l ver i n co i n (X-Ray), p i ct u r e t aken
wi t hout usi ng phot ographi c camera.
(b) Fu n g u s/ b act er i a (Bi o l o g y), p i ct u r e b y d i g i t al
camera highlight ing wit h cross light ing.
(c) Plant eat en by insect s/ worms (t oxicology), pict ure
by digit al camera.
IICT Pavilian in tha Save Energy Exhibition at Hyderabad
95
RESEARCH MANAGEMENT RESEARCH MANAGEMENT RESEARCH MANAGEMENT RESEARCH MANAGEMENT RESEARCH MANAGEMENT
The Resear ch Management Di vi si on of IICT p l ays a
pi vot al rol e i n t he management of research proj ect s
and vi t al act i vi t i es of t he Inst i t ut e. The pr oj ect s ar e
pl anned, moni t ored and eval uat ed by t he Research
Pl anni ng and Budget Commi t t ee and t he Resear ch
Co u n ci l o f t h e In st i t u t e. Th e Hu man Reso u r ce
Management Commi t t ee l ooks af t er t he depl oyment
of human resources. Vari ous act i vi t i es and f unct i onal
perf ormance duri ng t he peri od (2003-05) are gi ven
below:
*PROJECT MANAGEMENT
(a) CSIR Net woking Project s
IICT has been i dent i f i ed as t he nodal l aborat ory f or
coordinat ing 56 net working programmes / proj ect s for
i mp l ement at i on dur i ng t he X Fi ve Year Pl an p er i od
(2005-07) by net worki ng among t he CSIR l abs. These
l aborat ori es are: CIMAP, RRL( T), IHBT, RRL(Jorhat ), RRL
(Jammu), NCL, CFRI, IIP, CECRI, CSMCRI, and RRL (Bhu).
The t ot al out l ay of t hese proj ect s i s Rs.49.37 crores.
Research Management Di vi si on i s coordi nat i ng t hese
p r oj ect s and d et ai l s ar e g i ven i n CSIR Net w or ki ng
Proj ect s chapt er of t he report .
(b) Major Laborat ory Project s
IICT undert ook over 150 proj ect s / assignment s during
t he period in t he area of cont ract R&D / consult ancy /
Grant s-in-aid proj ect s. Overall ECF received during t hese
years and t he ECF chart s are given in t he beginning of
t he repor t . This division monit ors progress of proj ect s,
and communicat es wit h client s for receiving payment s.
Thi s di vi si on al so ar r anges f or hi r ed manp ower i .e.
proj ect assi st ant s and research f el l ows f or worki ng i n
t he proj ect s.
DATA BASE MANAGEMENT: This Division also maint ains
management i nf ormat i on syst em f or (a) proj ect s (b)
st aff (c) awards / honours (d) pat ent s filed / grant ed, (e)
cust omers sat isfact ion report s, et c. for monit oring t he
proj ect and provi di ng det ai l s t o Di rect or, IICT and t o
CSIR Hq.
*INTELLECTUAL PROPERTY RIGHTS
IICT has recognized t he import ance of t he IPRs by filing
pat ent applicat ions in India and overseas. This Division
ent huses scient ist s working in various divisions of t he
l aborat ory f or f i l i ng pat ent appl i cat i ons by renderi ng
assi st ance i n draf t i ng, scrut i ni zi ng and sendi ng t he
pat ent applicat ions t o IPM Division of CSIR Hq. The list
of t he pat ent s filed / grant ed is given in t he annexure.
* I NTERNATI ONAL S&T ACTI VI TI ES ( FOREI GN
DEPUTATIONS)
IICT scient ist s are deput ed t o at t end various import ant
int ernat ional seminars/ workshops and also for t raining
on sophi st i cat ed anal yt i cal i nst rument s and t o work
wit h fellow scient ist s in reput ed overseas universit ies.
Mor e t han 50 sci ent i st s / p er sonnel wer e d ep ut ed
abroad during t he last 2 years. RM Division coordinat es
wi t h CSIR Hq f or obt ai ni ng necessary approval s and
clearances for t hese deput at ions.
* * * * *SEMINARS
RM Di vi si on coor di nat ed t he act i vi t i es of Di amond
Jubilee Celebrat ions including seminars, curt ain raising
event on August 4,2003 and val edi ct ory f unct i on on
Aug ust 4,2004. Ever y year RM Di vi si on or g an i zes,
Nat i o n al Sci en ce Day, Nat i o n al Tech n o l o g y Day,
Founder s Day, Dr. Si dhu Sci ence Foundat i on and Dr.
P.S.Mu r t i Memo r i al Lect u r es. Emi n en t sci en t i st s/
i ndust ri al i st s/ academi ci ans are i nvi t ed t o del i ver key
not e address duri ng t hese days. Det ai l s are gi ven i n
Diamond Jubilee Celebrat ions chapt er.
National Science Day National Technology Day
Founders Day Lecture
96
The IICT-CCMB Library wit h it s rich reference collect ion
i n t he front i er areas of chemi cal , engi neeri ng and l i fe
sciences is consult ed not only by t he inst it ut ional users
but by researchers in and around Hyderabad.
The pri nt hol di ngs i ncl ude books, di ct i onari es, hand
books, encyclopedias, reference book series, et c and t he
back volumes of j ournals which are around one lakh in
number. The librar y subscribes t o around 430 Nat ional
and Int ernat i onal j ournal s.
The l i brary i s one of t he very f ew l i brari es i n Andhra
Pradesh whi ch has a compl et e col l ect i on of Chemi cal
Abst ract s from t he year of it s incept ion i.e 1907.
The l i brary has t aken act i ve st eps t o comput eri se i t s
operat ions and acquire digit al resources.
*DATABASE
This includes Chemical Abst ract s on CD , Indian, Brit ish
an d ASTM st an d ar d s o n CD, a CD co l l ect i o n o f
Companys Annual Rep or t s and ot her CDs r ecei ved
t hrough subscri pt i on of pri nt j ournal s. Dat abase are
made available t hrough t he Inst it ut es int ranet t o users
at user room facilit ies recent ly creat ed.
SCOPUS: It i s t he l ar g est ab st r act i ng and i nd exi ng
dat ab ase coveri ng more t han14,000 p eer revi ewed
j ournals from 4000 int ernat ional publishers along wit h
cit at ions search facilit y.
Sci Fi nder: It is a paid dat abase from American Chemical
Societ y for specific search by aut hor, t it le, st ruct ure, et c
in Chemical Sciences. Lect ure -cum-demo were arranged
for IICT scient ist s t o use t his facilit y from t he Publishers.
Fo l l o w i n g w er e t h e sp eci al t asks t h at h ave b een
achieved during t he period:
E-resources: In addi t i on t o Sci ence Di rect by El sevi er
Science Publishers , e-j ournals from 8 more publishers
have been added t hrough CSIR consort ium. In all, more
t han 3,700 j ournals can be accessed now at user s desk
t ops t hrough IICT int ranet . Some more e- j ournals have
also been made available for access by virt ue of IICTs
print subscript ion .
Training Programme : This was arranged for t he Librar y
and Inf or mat i on Of f i cer s of CSIR Lab or at or i es f r om
Cent ral India at t he request of NISCAIR of CSIR in using
t he e- j ournal s whi ch i ncl ude l ect ure-cum-demo by
publishers and officers from NISCAIR along wit h hands
on t rai ni ng.
INFORMATION MANAGEMENT INFORMATION MANAGEMENT INFORMATION MANAGEMENT INFORMATION MANAGEMENT INFORMATION MANAGEMENT
Library Homepage: A homepage of Library viz ht t p:/ /
libdoc was designed using Macromedia dream waiver
MX2004 and Macromedia fire works MX2004 t o bring
digit al and e-resources of library on a single plat form.
Library home page can be accessed via int ranet by users.
Through t his homepage user can access
- e-j o u r n al s- b o t h su b scr i b ed an d f r ee i n t er n et
j ournals,
- Daily new arrivals of j ournal issues in t he library
- List of IICT publicat ions wit h abst ract s
- Int ernet pat ent si t es
- Free Chemical Informat ion sit es on int ernet
* REORGANIZATION AND COMPUTERISATION OF
INDIAN PATENTS
As a measure of savi ng space and al so t o make t he
available Indian pat ent s ret rievable from t he year 1943
t o 1994 (2407pat ent s), l oose sheet s of Indi an pat ent s
were bound i nt o vol umes and shel ved accordi ng t o
t hei r pat ent speci f i cat i on number and comput eri zed
which are hit hert o irret rievable.
Remot e Access Service t o I CI CI Knowledge Park:
Consult ancy Proj ect sponsored by ICICI Knowledge Park
has been complet ed successfully as per t he t erms and
condi t i ons.
ECF Generat ion : Through Indust r i al membershi ps,
consult ancy and ot her services, t he division has earned
more t han Rs.40 Lakhs during t he period.
Archiving of IICT Publicat ions: Repri nt s of research
publicat ions from t he st aff of IICT were collect ed, indexed
and bound i nt o vol umes have been di spl ayed i n t he
Li brar y f or ready ref erence of t he Inst i t ut es research
out put .
Ot her Ser vices: Reprogr aphi c, Transl at i on, Bi ndi ng,
Documen t d el i ver y, et c Li b r ar y ser vi ces ar e b ei n g
cont inued for t he benefit of users.
97
98
99
HUMAN RESOURCE DEVELOPMENT HUMAN RESOURCE DEVELOPMENT HUMAN RESOURCE DEVELOPMENT HUMAN RESOURCE DEVELOPMENT HUMAN RESOURCE DEVELOPMENT
TRAINING PROGRAMMES
___________________________________________________________________________________________________
Course Date
___________________________________________________________________________________________________
Training Need Analysis, Human Pot ent ial Development 28
t h
t o 30
t h
Sept . 2004
Cent re, New Delhi
Insect Pheromones Research & Development Aspect s, 16
t h
t o 28
t h
Feb. 2004
Raj shree Sugars & Chemicals Lt d., Coimbat ore
Qualit y Cont rol of Herbal medicines, Sri J S Ayurvedic 19
t h
t o 24
t h
July 2004
College, Chennai
One day programme on coal t est ing and finger print ing of coal, 16
t h
July 2004
Si ngareni Col l eri es, Kot hagudam
Nat ional Workshop on Modern Chromat ographic 29
t h
Dec 2003 t o 2
nd
Jan. 2004
Techniques and t heir Applicat ions in Chemist r y, Biochemist r y
and Pharmacy, Dept . of Chemist r y, NIT, Warangal
Training programme for Sect ion Officers on Vigilance 7t h t o 9t h April, 2005
& relat ed issues, Human Resource Development Cent re,
Ghazi abad
Annual Meet 2004, of Coordinat ors, PME & 23rd & 24t h Jan. 2004
Finance Officials, CSIR, New Delhi
Advanced Course in Bioinformat ics Two Courses of long durat ion
(about 5 mont hs) conduct ed
during 2003- 04 and 2004-05
Training Programme for Section Officers Conducted by HRDC,
Ghaziabad at IICT
Dr. J.S.Yadav, Director, IICT(Seated third from left) at the National
Workshop - Modern Chromatographic Techniques at IICT
100
SYMPOSIA/ SEMINARS/ WORKSHOPS SYMPOSIA/ SEMINARS/ WORKSHOPS SYMPOSIA/ SEMINARS/ WORKSHOPS SYMPOSIA/ SEMINARS/ WORKSHOPS SYMPOSIA/ SEMINARS/ WORKSHOPS
ORGANISED BY IICT ORGANISED BY IICT ORGANISED BY IICT ORGANISED BY IICT ORGANISED BY IICT
2003 - 2004 2003 - 2004 2003 - 2004 2003 - 2004 2003 - 2004
Dr. R. K. Arora, Execut ive Direct or, C-DAC visit ed IICT as a Chief Guest on t he inaugural funct ion of Advanced Course
in Bioinformat ics (ACB) held on 25
th
June 2003 and Prof. Y. Venkat rami Reddy, Vice Chancellor, JNTU delivered a
speci al address.
Hi s excel l ency Shri Surj it Singh Barnala, t he Governor of Andhra Pradesh visit ed IICT and delivered t he 13
t h
Dr. G. S.
Sidhu Science Lect ure on Indian Science and it s Societ al Impact on 16
th
July 2003.
Dr. Mrs. Manj u Sharma, Secret ary, Dept . of Biot echnology, Minist ry of Science and Technology, Govt . of India, New Delhi
visit ed IICT and delivered Prof. Y. Nayudamma Memorial Lect ure on Biot echnology Research and Development
Towards Excellence and Self-Reliance for Human Welfare on 18
th
July 2003.
Shri Vadde Sobhanadreeswara Rao, Honble Minist er of Agricult ure, Govt . of Andhra Pradesh visit ed IICT as a Chief
Guest for t he Nat ional Seminar held on Recent R&D Trends in Rice Bran Oil Processing and By-product Ut ilizat ion
by IICT and Oil Technologist s Associat ion of India, Sout hern Zone on 30
th
August 2003.
Dr. Masami Inada, President M/ s Aisin Cosmos, Japan visit ed IICT as a chief Guest for t he Curt ain Raiser funct ion IICT
Diamond Jubilee Celebrat ions (1944-2004), held on 5
th
August 2003.
Prof. Chandrakant h Kokat e, Vi ce Chancel l or, Kakat i ya Uni versi t y, War angal vi si t ed IICT as a Chi ef Guest f or t he
Int ernat ional Seminar on Global Scenario of Herbal Medicine on 19
th
September 2003.
Dr. R. A. Mashelkar, Direct or General, CSIR & Secret ary, DSIR (GOI) visit ed IICT and launched t he IICT Diamond Jubilee
Init iat ives on 21
st
Sept ember 2003. Prof. R. Kumar, Chairman, IICT Research Council presided over t he funct ion.
Prof. Y. Venkat rami Reddy, Vice Chancellor, Jawaharlal Nehru Technological Universit y, Hyderabad visit ed IICT as a Chief
Guest for t he CSIR Foundat ion Day Celebrat ions held on 26
th
Sept ember 2003.
Dr. B. Chandra Kant Rao, Dent al Surgeon, Mahaveer Hospit al, Hyderabad visit ed IICT on 18
th
November 2003 delivered
a lect ure on Healt h Hazards of Tobacco Smoking as a part of Nat ional Pharmacy Week Celebrat ions.
Prof. M. S. Anant h, Direct or, Indian Inst it ut e of Technology, Chennai visit ed IICT t o inaugurat e t he Nat ional Seminar on
Fuel t o Fuel Cells from 4
th
t o 5
th
December 2003.
Shri C. V. Anand, IPS, Vice Presi dent , HCA, Hyderabad vi si t ed IICT as Chi ef Guest for t he Inaugural f unct i on of t he
Nayudamma Memorial Cricket Tournament from 11 14 December 2003.
Prof. N. Sat yamur t hy, Dean, Facul t y Af f ai rs, IIT, Kanpur vi si t ed IICT t o del i ver a t al k on t he IICT Diamond Jubilee
Teachers Day Celebrat ions organized j oint ly by IICT and AP Akademi of Sciences on 5
th
Sept ember 2003. Prof. P. K. Sai
Prakash, Hon. Secret ary, APAS and Dr. Rat an F. Toorkey, Polymer chemist , EMRC, CIEFL, Hyderabad conduct ed scient ific
sessions for t he benfit of st udent s.
Prof. Mukul Chand Panday, Member, Hindi Advisor Commit t ee, Home Minist r y, Govt . of India and Prof. C. Subba Rao, AP
St at e Higher Educat ion Board, Hyderabad visit ed IICT as t he Chief Guest s for t he Hindi Day Celebrat ions on 15
th
Sept ember 2003.
SYMPOSIA/ SEMINARS/ WORKSHOPS SYMPOSIA/ SEMINARS/ WORKSHOPS SYMPOSIA/ SEMINARS/ WORKSHOPS SYMPOSIA/ SEMINARS/ WORKSHOPS SYMPOSIA/ SEMINARS/ WORKSHOPS
101
Dr. P. M. Bhargava, Former Direct or of CCMB visit ed IICT as a Chief Guest for launching of K T Achaya Endowment Fund
and t o deliver t he 1
st
K T Achaya Memorial Lect ure on 6
th
October 2003.
Dr. C. L. Khet rapal , FNA & Di st i ngui shed Professor, Cent re f or Bi omedi cal Magnet i c Resonance, Sanj ay Gandhi P. G.
Inst it ut e of Medical Sciences, Lucknow visit ed IICT t o deliver IICT Founders Day Lect ure on 7
th
November 2003.
Dr. D. S. Viswanat h, Emerit us Professor and Dowell Chair at t he Universit y of Missouri, Columbia (USA), visit ed IICT as
Chief Guest and delivered 8
th
P. S. Murt i Memorial Lecture on 10t h January, 2004.
Dr. R. N. Singh visit ed IICT as a Chief Guest for t he Six Day Nat ional Workshop on Indust rial Applicat ions of Chemo-
informat ics and Comput er Aided Drug Design held on 12 17 January 2004. Prof. E. D. Jemmis was t he keynot e
speaker.
Prof. Kl abunde, Uni versi t y Di st i ngui shed Professor, Kansas St at e Uni versi t y, USA vi si t ed IICT t o del i ver a l ect ure on
Nanoscale Mat erials on 23
rd
January 2004.
2004 - 2005 2004 - 2005 2004 - 2005 2004 - 2005 2004 - 2005
Dr. (Mrs.) Manj u Sharma, Adviser t o Minist er for Science & Technology, Govt . of India visit ed IICT t o deliver 12
th
S S
Bhat nagar Memorial Lect ure, on 1
st
April 2004.
Dr. D. P. Rao, Former Direct or, NRSA visit ed IICT as t he Chief Guest for t he World Eart h day at IICT on 22
nd
April 2004.
Dr. S. Jeevananda Reddy, Agricult ural Met eorologist delivered a lect ure on t his occasion.
Dr. A. V. Rama Rao, Former Direct or and Chairman & Managing Direct or of M/ s AVRA Labs, Hyderabad visit ed IICT t o
deliver a lect ure on Nat ional t echnology Day at IICT on 11
th
May 2004.
Dr. R. N. Singh, Ex-Direct or, NEERI, Nagpur visit ed IICT as t he Chief Guest for t he seminar on Virt ual Realit y in Pursuit
of Excellence held at IICT on 4
th
June 2004 as part of t he IICT Diamond Jubilee celebrat ions.
Prof.S.K.Brahmachari , Direct or, IGIB, New Delhi visit ed IICT t o deliver t he 14
t h
Sidhu Science Lect ure on SNPs, Chips,
Informat ics and Predict ive Medicine on 2
nd
July, 2004 at NGRI, Hyderabad.
Prof. Ab r aham Cl ear f i el d, Texas A & M Uni ver si t y, USA vi si t ed IICT t o del i ver a l ect ure on A New Fami l y of
Supermicroporous Oxides on 21
st
August 2004.
Inauguration of the Workshop Industrial Applications of
Chemoinformatics and Computer aided Drug Design at IICT
Symposia / Seminars / Workshops
102
Prof.Nit yananda Saha, Vice Chancellor, Kalyani Universit y, West Bengal was t he Chief Guest for t he CSIR Foundat ion
Day celebrat ions held on 26
th
September, 2004.
Prof.Animesh Chakravort hy, IACS, Kolkat a visit ed IICT t o deliver Founder s Day lect ure on A Port rait of Met al Ions
on 9
th
November, 2004 in memory of Lat e Dr.S.Husain Zaheer, Ex-Direct or, IICT and Ex-DG, CSIR.
Prof. Javed Iqbal of Dr.Reddys Research Foundat i on of Hyderabad was t he chi ef guest for t he one day nat i onal
seminar on Indust rial Perspect ive of Bioinformat ics organised on 18
th
November, 2004 and several eminent
speakers from TCS, IISc, Jubilant Biosys, V-Life Sciences, Schroeindger and Ocimum Biosolut ions part icipat ed in t he
seminar.
Prof.Jayant M.Modak, IISc, Bangalore delivered t he 9
t h
Dr.P.S.Murt i Memorial Lect ure on 10
th
January, 2005 at IICT on
Biot echnology for Refract ory Gold Ores.
Prof.S.Jayarama Reddy, Vice-Chancellor, S.V.Universit y, Tirupat i delivered an invit ed lect ure on 27
th
January, 2005 at
IICT on Elect rochemical Techniques: Their Pot ent ialit ies in Analysis and Synt hesis.
Nobel laureat e Prof. Shirakawa delivered lect ure on Synt hesis of Polyacet ylene at IICT on 9
th
February 2005.
Dr.B.M.Choudar y, Ex-Deput y Di rect or, IICT delivered a lect ure on Nat ional Science Day celebrat ed in collaborat ion
wit h APCOST on Asymmet ric synt hesis in commemorat ion of Einst ins discover y in 1905 being celebrat ed wit h
focus on physics in 2005, held on 28
th
February 2005.
Dr.S.Si ddi qui , Uni versi t y of Il l i noi s , Chi cago (USA) del i vered a l ect ure on TGF- Signaling in Development and
Wound healing on 14
th
March, 2005.
Prof. Lakshmi Kot ra, Di rect or, Molecular Design and Informat ion Technology Cent re, Universit y of Toront o, Canada
delivered a lect ure on Structure based Design of Insulin Receptor ligands on 18
th
March 2005.
Dr. Pat rice Rannous from Synt het ic Met als Laborat or y, France delivered a lect ure on Ionically Self-Organized and
Hierarchize Met allic and Thermo st ab Poly (aniline) Comb-Shaped Supramolecules: From Basic Science t o
Plastic Electronic Applications on 22
nd
March 2005.
Prof. Pierre H. Dixneuf, Universit y of Rennes, France delivered a lect ure On Ruthenium Catalysts And Fine Chemistry
on 29t h March, 2005.
Prof. D.S. Viswanath, Emeritus Professor & Dowell Chair at the University & Missouri,
USA (second from left) delivered the 8th P.S. Murti Lecture at IICT (10-01-2004)
103
AWARDEE(S) AWARDEE(S) AWARDEE(S) AWARDEE(S) AWARDEE(S) AWARD/ RECOGNITION AWARD/ RECOGNITION AWARD/ RECOGNITION AWARD/ RECOGNITION AWARD/ RECOGNITION
* Dr. J.S. Yadav Dr. J.S. Yadav Dr. J.S. Yadav Dr. J.S. Yadav Dr. J.S. Yadav O Goyal Prize (2003) in Chemist ry by t he Kurukshet ra
Uni versi t y
O Vi gyan Rat na Award (2002-03) by t he Counci l of
Science & Technology, UP.
O Vigyan Gaurav Samman (2004) by t he Council of
Science & Technology, UP
O Upgradat ion in t he Addl. Secret arys Grade based
o n t h e r eco mmen d at i o n s o f Hi g h Po w er ed
Commit t ee const it ut ed by t he Vice President , CSIR.
* Dr. T.K.Chakraborty Dr. T.K.Chakraborty Dr. T.K.Chakraborty Dr. T.K.Chakraborty Dr. T.K.Chakraborty O AP Scient ist Award 2005 by t he AP Akademi of
Sciences
* Dr. B.M. Choudary Dr. B.M. Choudary Dr. B.M. Choudary Dr. B.M. Choudary Dr. B.M. Choudary O Fellow, Indian Nat ional Science Academy
O Andhra Pradesh scient ist Award (2004) by t he AP
St at e Council of Science & Technology
* Dr. Prakash V Diwan Dr. Prakash V Diwan Dr. Prakash V Diwan Dr. Prakash V Diwan Dr. Prakash V Diwan O C K Dandiya Award in Pharmacology (2003)
O Prof . B N Ghosh Orat i on Award f rom t he Indi an
Pharmacological Societ y, New Delhi
O Compl et ed Laborat or y Assessor Trai ni ng Course
or gani zed b y Nat i onal Accr edi t at i on Boar d f or
Test ing & Calibrat ion Laborat ories, New Delhi.
* Dr. R.B.N. Prasad Dr. R.B.N. Prasad Dr. R.B.N. Prasad Dr. R.B.N. Prasad Dr. R.B.N. Prasad O Edit or, Journal of Oil Technologist s Associat ion of
India (OTAI)
O Dr S Husain Zaheer Award (2002) OTAI
O Dr S D Thirumala Rao Memorial Award (2003) OTAI
O FAPCCI Award (2003-04) (Chel i kani At chut a Rao
Memorial Cash Award)
* Shri K.V.R.S. Murthy Shri K.V.R.S. Murthy Shri K.V.R.S. Murthy Shri K.V.R.S. Murthy Shri K.V.R.S. Murthy O Chairman, Indian Inst it ut ion of Plant Engineers-
AP chapt er and Vice President , Indian Inst it ut ion
of Plant Engineers- Chennai (Sout hern Region)
* Dr. D. Krishna Dr. D. Krishna Dr. D. Krishna Dr. D. Krishna Dr. D. Krishna O Hon. Member, Board of St udies in St at ist ics under
Facult y of science, Osmania Universit y, Hyderabad.
O Joi nt Secret ar y, Soci et y f or t he devel opment of
St at i st i cs
HONOURS AND AWARDS HONOURS AND AWARDS HONOURS AND AWARDS HONOURS AND AWARDS HONOURS AND AWARDS
104
* Dr. U.S.N. Murthy Dr. U.S.N. Murthy Dr. U.S.N. Murthy Dr. U.S.N. Murthy Dr. U.S.N. Murthy O Member, Governi ng Counci l & Research Counci l ,
AP St at e Sericult ure Development Inst it ut e
* Dr. S.Chandrasekhar Dr. S.Chandrasekhar Dr. S.Chandrasekhar Dr. S.Chandrasekhar Dr. S.Chandrasekhar O AVRA Young Scient ist Award 2004
* Dr. J.V. Rao Dr. J.V. Rao Dr. J.V. Rao Dr. J.V. Rao Dr. J.V. Rao O Memb er, Bo ar d o f St u d i es, Bi o t ech n o l og y,
Osmani a Uni versi t y, Hyderabad
* Dr. (Mrs) P.Usha Rani Dr. (Mrs) P.Usha Rani Dr. (Mrs) P.Usha Rani Dr. (Mrs) P.Usha Rani Dr. (Mrs) P.Usha Rani O Dr. (Mrs) Jagdi shwar i Rao Award 2004 by t he
Appl i ed Zool ogi st s Research Associ at i on (AZRA)
* Dr. V.J. Rao Dr. V.J. Rao Dr. V.J. Rao Dr. V.J. Rao Dr. V.J. Rao O Chemical Research Societ y of India, Bronze Medal-
2004
* Dr. R. Nageswara Rao Dr. R. Nageswara Rao Dr. R. Nageswara Rao Dr. R. Nageswara Rao Dr. R. Nageswara Rao O Out st anding Pharmaceut ical Analyst Award (2004)
by t he Indi an Drug Manuf act urers Associ at i on
(IDMA)
* Dr. Ch. Venkateswarlu Dr. Ch. Venkateswarlu Dr. Ch. Venkateswarlu Dr. Ch. Venkateswarlu Dr. Ch. Venkateswarlu O Associat es Fellow, AP Akademi of Sciences
* Dr. K.V.S.N. Raju & Dr. K.V.S.N. Raju & Dr. K.V.S.N. Raju & Dr. K.V.S.N. Raju & Dr. K.V.S.N. Raju & O Indian Paint Associat ion (IPA) Award-2004
Shri D.K. Chatopadhyay Shri D.K. Chatopadhyay Shri D.K. Chatopadhyay Shri D.K. Chatopadhyay Shri D.K. Chatopadhyay
* Dr. Paramjit Grover Dr. Paramjit Grover Dr. Paramjit Grover Dr. Paramjit Grover Dr. Paramjit Grover O Fellow, Academy of Sciences for Animal Welfare
* Dr. U.C. Kulshrestha Dr. U.C. Kulshrestha Dr. U.C. Kulshrestha Dr. U.C. Kulshrestha Dr. U.C. Kulshrestha O CSIR Young Scient ist Award (2004) in Eart h,
At mosphere, Ocean & Planet ary Sciences
O M S Krishnan Gold Medal (2004) inst it ut ed by t he
Indian Geophysical Union
* Dr. M.S.L. Karuna Dr. M.S.L. Karuna Dr. M.S.L. Karuna Dr. M.S.L. Karuna Dr. M.S.L. Karuna O O P Narula Young Scient ist Award (2003) OTAI
* Dr. P.P. Chakrabarti Dr. P.P. Chakrabarti Dr. P.P. Chakrabarti Dr. P.P. Chakrabarti Dr. P.P. Chakrabarti O Jt . Edit or, Journal of Oil Technologist s Associat ion
of India (OTAI)
* Shri S. Sridhar Shri S. Sridhar Shri S. Sridhar Shri S. Sridhar Shri S. Sridhar O Amar Dye-Chem Award of IIChE (2003)
O Nat ional Award for Excellance in R & D for Chemical
Engineering by IIChE in 2003
* Dr. Sanjit Kanjilal Dr. Sanjit Kanjilal Dr. Sanjit Kanjilal Dr. Sanjit Kanjilal Dr. Sanjit Kanjilal O O P Narula Young Scient ist Award (2002)-OTAI
* Shri K.V.S. Ranganath Shri K.V.S. Ranganath Shri K.V.S. Ranganath Shri K.V.S. Ranganath Shri K.V.S. Ranganath O Dr K V Rao Scient ific Societ y Award
* Shri A. Prabhakar Shri A. Prabhakar Shri A. Prabhakar Shri A. Prabhakar Shri A. Prabhakar O Dr.K.V.Rao Scient ific Societ y Award
* Miss B. Smitha Miss B. Smitha Miss B. Smitha Miss B. Smitha Miss B. Smitha O Lat e Laxmi Nan d ku mar Aw ar d f o r b est
Present at ion at CHEMCON-2004
105
DIRECTOR
DR. J.S. YADAV
SCI ENTI ST-G
DR. A. C. KUNWAR
DR. M. VAIRAMANI
SCIENTIST-F
DR. G.S. SALVAPATI
SRI. VEDANTA CHARY
DR. K.B.S. PRASAD
DR. K. BABU RAO
DR. C.V.S. MURTY
DR. B. VISHWANADHAM
DR. P.S. SAI PRASAD
SRI. K.B.S. SAIBABU
DR. P. NAGESHWARA SHARMA
SRI. PRADEEP KUMAR
DR. Y. BHASKAR RAO
SRI. G. SAMPATH KUMAR
SRI. AHMED KHAN
SRI. S. NARAYAN REDDY
SRI. VIJAY KALE
SRI. B. SANKARIAH
SRI. K. VENKATESHWARLU
DR. N.KISHAN REDDY
SRI. K. PREM KUMAR
SRI. S. VENKATESWARA RAO
DR. MOHD. KIFAYATULLAH
DR. B.B. GAWALI
SRI. A. KRISHNA REDDY
SRI. K. RAJESWARA RAO
SRI. B. BAL REDDY
SRI. M.R.K. MURTHY
SRI. K.V.R.S. MURTHY
DR. R.B.N. PRASAD
DR. M. RAMAKRISHNA
SRI. C.V. SUBBA RAO
DR. D.H.L. PRASAD
SRI. K.V. RAMANAYYA
DR. V.V. NARAYANA REDDY
DR. AHMED KAMAL
DR. D. KRISHNA
DR. B. NARSAIAH
DR. B. VITTAL RAO
DR. PRAKASH V. DIWAN
DR. K. RAMA RAO
DR. R. ADAPA SRINIVAS
DR. U.S.N. MURTHY
DR. M. LAKSHMI KANTAM
SRI S.J.D. VARAPRASAD
DR. M. SUBRAHMANYAM
DR. T.K. CHAKRABORTY
DR. M. HARI BABU
DR. J. MADHUSUDANA RAO
DR. I. SURYANARAYANA
DR. B. RAMACHANDRA REDDY
SRI. G.A. REDDY
SCIENTIST-EII
DR. S. CHANDRASEKHAR
DR. G.V. MADHAVA SHARMA
DR. T.N. SRINIVASAN
SRI. K.S. RAGHUNANDAN
SRI. K.V.S.A. RAO
DR. MS. P. SITADEVI
MS. KRUPADEVI OMPRAKASH
SRI. S.V.S. RAJU
SRI. T.E. VITTAL PRASAD
SRI. R.K. VENKATA RAMANA
SRI. T. RAJAIAH
SRI. G. RAVINDRANATH
SRI. T. SURYANARAYANA
SRI. K.V.L.N. PRAKASH
SRI. V. RAJAGOPAL
DR. CH. VENKATESWARLU
DR. A.S.R. KRISHNA MURTHY
SRI. P.S. BHASKAR
DR. B.S. SITARAMAM
SRI. M.G.V. CHALAPATHI RAO
DR. M. MARTHANDA MURTHY
DR. MS. B. KRISHNAKUMARI
SRI. G. NARSIMHA REDDY
DR. Y.V.D. NAGESWAR
DR. V. VENKAT RAO
MS. SAKTIMAYEE MITRA ROY
SRI. I. BALAKISHAN RAO
DR. V. VIJAY KUMAR
SRI. K. RADHAKRISHNAN
DR. MS. ANNAPURNA JETTY
SRI. B. BHOOLOKA RAO
SRI. C.P. RAMULU
DR. MS. C. SNEHALATHA NAIR
DR. P. VIJAYALAKSHMI
SRI. SHARAD SHIRADKAR
SRI. J.V. PRASAD
MS. USHA VIRENDRA REDDY
SRI. D.M. AKKEWAR
SRI. B. MADHUSUDHAN
DR. A. SESHU KUMAR
DR. K. ISHRATULLA
DR. M.S.R. MURTHY
DR. L.V. SIVAJI
DR. MS. V. DURGA KUMARI
SRI. P. RAVI PRASAD
SRI. K.H.V. PRASAD
SRI. T. KRISHNUDU
SRI. D.V. MOHAN RAO
DR. A. BHASKAR RAO
SRI. K. RAVINDRANATH
DR. K. JEEVA RATNAM
DR. P. SHANTHAN RAO
DR. MS. P. USHA RANI
DR. R. NAGESWAR RAO
DR. A.R. PRASAD
DR. Y. RAM BABU
DR. B. MAHIPAL REDDY
DR. R. SRINIVAS
DR. MS. S.S. MADHAVENDRA
DR. B. JAGANNADH
DR. R. NARENDER
DR. IMTIAZ AHMED ANSARI
DR. H.M. MESHRAM
DR. M. RADHAKRISHNA
DR. Y. VENKATESWARULU
SRI. N.W. FADNAVIS
DR. J. VENKATESWARA RAO
DR. V. VISWANATHAN
DR. S.J. KULKARNI
DR. V. JAYATHIRTHA RAO
DR. K. RAVI KUMAR
DR. B.S. RAO
DR. BISWANATH DAS
DR. K. BHANU PRAKASH
DR. PARICHAY KUMAR DAS
DR. B. VENKATESWARA RAO
DR. K.V.R. CHARY
DR. ARABINDA CHAUDHURI
MS. C.B. LAKSHMI
DR. K. CHANDRA SEKHAR
SCIENTIST-EI
DR. K.V.S.N.RAJU
SRI. C.L.N. MURTHY
DR. K.S. RAMA RAO
DR. MS. PARAMJIT GROVER
DR. B. RAMA RAO
DR. K. SIVAJI
STAFF AS ON 01/ 04/ 2005 STAFF AS ON 01/ 04/ 2005 STAFF AS ON 01/ 04/ 2005 STAFF AS ON 01/ 04/ 2005 STAFF AS ON 01/ 04/ 2005
106
DR. R. SEKHAR
DR. A. KRISHNAIAH
SRI. HARISIMHA
DR. U. ASHUTOSH
DR. MS. K. YAMUNARANI
DR. D. VIJAYAKUMAR
DR. P. RADHAKRISHNA
SRI. D.V.R. MURTHY
DR. K. NAGAIAH
MS. D. SHAILAJA
DR. D. SUBHAS BOSE
DR. MS. LALITHA KUMARI
DR. MS. G. SABITHA
SRI. K. SATYANARAYANA
DR. R.S. PRAKASAM
SRI. M.H. UPADHYAYA
SRI. G.A. RAJU
DR. G. KUMARASWAMY
SRI T. SHEKHARAM
DR. S. RAGHAVAN
DR. S. PALANIAPPAN
DR. B. JAGADEESH
DR. A.K. TIWARI
SRI. JOHNY JOSEPH
DR. MRS. K.N. JYOTHI
DR. MRS. A.L. PRASUNA
DR. G. NARAHARI SASTRY
DR. MS. S.V. MANORAMA
DR. B. SREEDHAR
MR. A. GANGAGNI RAO
SCI ENTI ST-C
DR. TAIMUR ATHER
SRI. PRAVIN RABAJI LIKHAR
SRI. M. RAMULU
SRI. P. SAMMAIAH
SRI. T. PRATAP KUMAR
DR. B. DAVID RAJU
DR. K.SRINIVAS
SRI. B.V.SATYA RAMESH
DR. K.I. SURESH
MS. S.INDU KUMARI
DR. B.L.A. PRABHAVATHI DEVI
DR. S. RAMA MOHAN
DR. MS. B. SATYAVATHI
SRI. S. ANAND KUMAR
SRI. S. SRIDHAR
DR. M. SRIDHAR
DR. N. LINGAIAH
DR.PRADOSH P. CHAKRABARTI
MS. A. MANJULA
SRI. S. PRABHAKAR
DR. U.C. KULSHRESTHA
DR. MS. GHOUSIA BEGUM
MS. K.N. PRASANNA RANI
DR. MS. G. SARALA DEVI
DR. M. MOHAN RAO
DR. S. RAMAKRISHNA
SRI. M. CHANDRASEKHARAM
SRI. T.V.S.N. MURALI KRISHNA
SRI. M. PRADEEP KUMAR
DR. RAJIV TRIVEDI
DR.(MRS) MONIKA J. KULSHRESTHA
DR. RAJKUMAR BANERJEE
DR. A.V. SUBRAHMANYA SARMA
DR. ROHIT KUMAR RANA
SCIENTIST-B
DR. P. ARUNA
DR. B. SRIDHAR
DR.(Mrs) SOUJANYA YARASI
DR. B. CHINNA RAJU
MS. M. SRI LAKSHMI KARUNA
MS. SUTAPA GHOSH
SRI. SAMUEL L. RALTE
DR. N. NARENDER
DR. H. MAHESWARAN
DR. A. VENUGOPAL
DR. K. RAJENDER REDDY
SRI G. UMA SANKAR
DR. N. LINGAIAH
SRI. U.V.R. VIJAYA SARATHI
SRI. R. SRINIVASAN
MRS. C. SUMANA
DR. S. VENKATA MOHAN
SRI. P.V. SRINIVAS
TECHNICAL OFFICER EII
SRI. K.V. AVADHANULU
SRI. B. PRAKASH RAO
SRI. UDAY RANGREZ
DR. MS. BHARATHI DEVKUMAR
TECHNICAL OFFICER EI
SRI. K. BHUPAL REDDY
SRI. C.R.C. RAJU
DR. A.R.K. SASTRY
SRI. P. DATTATREYA SARMA
SRI. K. RAMACHANDRA RAO
SRI. AHMED HUSSAIN
SRI. M. RAGHUVIR
SRI. B. VASUDEVA
MS. T.S. CHANDRA KALA
SRI. J. NARASIMHA CHARY
SRI. D. RAMAKRISHNA
SRI. C. LAKSHMI KANT RAO
SRI. P. YOGENDRANATH
SRI. G. RAJESHWAR RAO
SRI. P. RAMA RAO
SRI. ARIVENI SATYANARAYANA
SRI. K.V. RAMANAMURTHY
SRI. S. TAJUDDIN
SRI. R. NARSIMHA
SRI. N.S. SWAMY
DR. V.S. KISHAN PRASAD
SRI. ARUN KANTI DAS
DR. M. VENKATESWARA RAO
SRI. A. KUMAR
SRI. K. NARSIMAIAH
SRI. A.P. RUDRA DASS
SRI. S.K. ROY
DR. MS. K. PARVATI
SRI. HARSHA VARDHAN
SRI. B. KRISHNAMACHARYULU
DR. N. PRASADA RAJU
SRI. P.V.K. RAJU
SRI. E.V.R. HANUMANTH RAO
DR. K. KOTESWARA RAO
SRI. C. EFREM
SRI. K. SITARAMA RAO
DR. K. RAMAKRISHNAM RAJU
SRI. P. NAGESWAR RAO
TECHNICAL OFFICER-C
SRI. MOHD. RIAZUDDIN
SRI. B.R. VENKATESHAM
SRI. ARADADA SATYANARAYANA
SRI. C. RAMACHANDRAN
SRI. N. PREM KUMAR
SRI. V.G. JACOB
SRI. S. CHANDRA REDDY
SRI. M. SOMESWAR REDDY
DR. B.V.S.K. RAO
SRI. A. RAMACHANDRA RAO
SRI. M. SUBRAMANYAM
DR. MS. I. MARGARET
SRI. K.V. VENKATESWAR RAO
SRI. K. GOPI KRISHNA
107
SRI. A. VISHWANATH
SRI. G. RANGA RAO
SRI. G. VIJAYA MURTHY
SRI. CH. BABU RAO
SRI. P. KRISHNA MURTHY
SRI. N. NALINI SEKHAR
SRI. ATUL NANDEDKAR
SRI. K. SHANMUGAM
MS.SHOBHA RAJENDRAPATHAK
SRI. A. MADHAVA RAO
DR. MOHD. MAHBOOB
SRI. A. NARASIMHA RAO
SRI. Y.V.L. RAVI KUMAR
SRI. A.S.P. RANGA PRASAD
DR. D. RAJA GOPAL
DR. G.Y.S. KUMARA SWAMY
SRI. A. RADHAKRISHNA
SRI. P. SIVAJEE
SRI. C. SUDHAKAR
DR. RAJEEV ARAB
SRI. P. RAMAKRISHNA RAO
SRI. G. VASUDEVA RAO
DR. MOHD. FAZLUR RAHMAN
TECHNICAL OFFICER-B
SRI. Y. CHANDRASEKHAR
SRI. K.V. SATYANARAYANA MURTHY
SRI. D. KRISHNA
SRI. A. SUDHAKAR REDDY
SRI. P. BICHAPPA
SRI. V. SIVARAMA SASTRY
MS. D. GAYATRI
SRI. G. NAGI REDDY
SRI. S. HEMANT KUMAR
MS. K.B. AMITA
DR. MS. M. SATYAKALA
SRI. T. PRABHAKAR RAO
SRI. T. VENUGOPAL RAJU
SRI. K. SRIRAM
SRI. DAMODAR JOSHI
DR. HAFEEZ - UR - REHMAN
SRI. T. NAGESHWAR RAO
MS. SARA KHALID
MS. K. BHUVANESHWARI
MRS. G. SHEELU
SRI. S. SRIKAMAL
DR. G. BASKAR RAJAN
TECHNICAL OFFICER-A
SRI. Y. SRI RAMA MURTHY
SRI. RAVILUKE BABU
SRI. T. MAHESH BABU
SRI. K.S.A. VISHNUVARDHAN
SRI. P. RAVINDER GOUD
DR. MS. M. SHYAMALA
DR. S. RAJARAM
SRI. B.S. SASTRY
SRI. U. SAMPATH KUMAR
DR. K. VENKATRAM REDDY
SRI. B. ASHOK KUMAR
SRI. CH. RAMESH
SRI. M. SRIDHAR KUMAR
SRI. K. SHIVA KUMAR
SRI. L. SATYANARAYANA
SRI. J. LAXMI KANTH RAO
SRI. A. RAMA KRISHNA REDDY
SRI. K. SUGNANA SUNDER
SRI. A. VENKATA NARSAIAH
SRI. B. RAJA SHAKER
MS. B. RENUKA
SRI. K. SARAVANAN
SRI. SUNIL KUMAR
SRI. B.V. DEVENDRA RAO
EXECUTIVE ENGINEER
SRI. P. NARAYANA RAO
ASSISTANT ENGINEER
SRI. CH. SRINIVAS
MEDICAL OFFICER
DR. MS. V. VARSHA GAYDHANKAR
SR.TECHNICAL ASSISTANT
(GR.III)
SRI. K. KIRAN
SRI. R.BOOPATHY
SRI. G. RADHA KRISHNA MURTHY
TECHNICAL ASSISTANT (GR.VIII)
(GR.III)
MRS. BHAGYA LAKSHMI M.G.
SRI. KIRAN KUMAR A.
SRI. MADHU SUDHANA K.
SRI. MURTY MRVS.
SRI. NARSINGH K.
SRI. NIRANJAN A.
SRI. RAVI KIRAN I.
SRI. RAVINDER T.
MS. ROHITHA C.N.
SRI. SATISH KUMAR D.
SRI. SATYA RAO D.
SRI. P. SIVA NARAYANAN
SRI. SRINIVAS PVSS
TECHNICAL OFFICER A
(GR.II)
SRI. S. JANAKIRAMAN
SRI. V. KRISHNAMA CHARY
SRI. MOHD. ISHAQ ALI
SRI. SYED KURSHEED AHMED
SRI. S. NARSING RAO
SRI. D.PENTAIAH / NARASIMHA
SRI. MOHD. IQBALUDDIN
SRI. P. YADAGIRI / DURGAIAH
SRI. P. RANGAIAH / KISTAIAH
SRI. M. SANJEEVA RAO
SRI. SALAHUDDIN
SRI. SALLAHUDDIN AHMED
SRI. P. VEERABHADRA RAO
SRI. K. YADGIRI / MALLIAH
SRI. R.RAMULU / MUTHAIAH
SRI. G. CHANDRAIAH
SRI. B. VENKATESHAM /
NARASIMHA
SRI. K. MALLA REDDY
MS. FATIMA ALI KHAN
SRI. P. NIRANJAN RAO
SRI. SYED KAREEMUDDIN
SRI. P. SATHYA PRASAD
SRI. P. C. LOHAR
SRI. J. ASHAIAH
SRI. RAJ BHOOMAIAH
SRI. M.C. THOMAS
SR. TECHNICAL ASSISTANT
(GR.II)
SRI. ABBAS ALI/ LIAQAT ALI
SRI. ABDUL AZEEM/ RAOFF
SRI. ABDUL REHMAN
SRI. ADISHESHU Y.
SRI. AMARENDRA KUMAR P.
SRI. ATHER MEHDI S.
SRI. BABU
SRI. BALARAJ E.
SRI. MD. BHAVALISHA
SRI. BHIKSHAPATHI K.
Staff As on 01/ 04/ 2005
108
SRI. BIKSHAPATHI D.
SRI. CHANDRAPAL M.R.
SRI. CHARAVANDA REDDY E.
SRI. DANAIAH K.
SRI. EASHWARAIAH K.
SRI. EASHWARJI N.
SRI. GOVERDHAN R.
SRI. KAMALAIAH C/ RAMASWAMY
SRI. KAMESHWAR RAO K.
SRI. LACHAIAH
SRI. LINGAM D.
SRI. J.V. S.N. MURTHY
SRI. MAHBOOB SHAREEF
SRI. MALLESHAM K.
SRI. MOHAN RAO R.
SRI. MOHD. GHOUSUDDIN
SRI. MOHD. IQBALUDDIN
SRI. T. SRINIVASAN
SRI. MOHD. ISHAQ ALI
SRI. MOHD. SARDARUDDIN
SRI. MOHD. TAJUDDIN
SRI. MOHD.HAYAT/ OSMAN
SRI. MURARILAL N.
SRI. NAGESHWAR RAO V.
SRI. NANDA GOPALAM G.
SRI. NARASIMHA D/ RAMULU
SRI. D. SHANKARIAH / MYSAIAH
SRI. BALAIAH / POCHAIAH
SRI. MOHD. WAHIUDDIN
SRI. P.V. SAIBABU
SRI. M. KHADEER KHAN
SRI. NARASIMHA REDDY E.
SRI. NARASIMHA/ MAISHAIAH B.
SRI. NASEERUDDIN ALVI DR. S.
SRI. OOSHAIAH/ THRUPATAIAH S.
SRI. PRASADA RAO D.
SRI. QAISER ALI
SRI. RAJA RATHNA N.
SRI. RAM MOHAN RAO P.
SRI. RAMACHANDRAIAH B.
SRI. RAMESH P.
SRI. RAMULU M/ RAJAIAH
SRI. RAMULU R/ MUTHAIAH
SRI. RAVI P.V.
SRI. RAVINDER A.
DR. K.V. RAMPRASAD
SRI. M. SYAM SUNDER
SRI. SANJAY B.D.
SRI. SAYED AZIZ
MS. SHASHIREKHA V.
SRI. SHIVAJI G.R.
SRI. SIDDIRAMULU M.
SRI. SRIDHAR B.
SRI. SUGREEVA REDDY N.
SRI. SWAMY J.
SRI. SWAMY/ SOMAIAH N.
MRS. SYEDA BEGUM
SRI. SYED KURSHEED AHMED
SRI. SYED MASID MIAN
SRI. SYED ZAFAR ALI
SRI. UTTAM KUMAR M.
SRI. VARDHARAJAN S.
SRI. VEERAIAH/ ELLAIAH
SRI. VENKATESHWARA RAO M.
SRI. VIJAY KUMAR B.
SRI. VIJAYA KUMAR CH.
SRI. VIJAYAN K.V.
SRI. VIVEKANANDA T.G.
SRI. YADAGIRI G/ MANKAIAH
SRI. YADAGIRI P/ DURGAIAH
SRI. YOUSUF ALI
SRI. ABDUL MANNAN
SRI. AHMED BIN ABUBAKER
SRI. JAI PRAKASH
MS. SUMATHI REDDY S.
MS. SURYA KUMARI K.
SRI. SYED BABU
SRI. UMA MAHESWARA SARMA V.
MS. URMILLA REDDY
SRI. K.V.N. SATYA SRINIVAS
SRI. J. SRI RAM MURTHY
SRI. T. RAMESH BABU
SRI. G. VEERAIAH
SRI. B. CHANDRASEKHAR
SRI. LAKSHMI PATHI RAJU V.
TECHNICAL ASST. GR.VII (GR.II)
SRI. ACHAL SINGH
SRI. ANJAIAH N.
SRI. FARHATH HUSSAIN
SRI. KALIDAS S. S/ O YADAGIRI
SRI. MADAN KUMAR S/ O SAMBIAH
SRI. MADHUSUDAN RAO K.
MS. MERCY JOSEPH
SRI. P.B. GAWALI
SRI. R. MAHESHWAR RAO
SRI. K. VENKATA NARAYANA
MRS. CH. JAGADESWARI
SRI. T. KRISHNA REDDY
SRI. MOHD. WAHIUDDIN
SRI. MOHD. AKBAR
SRI. NAQVI S.B.A.
MS. NILOFER RAHMAN
MS. PARVATHI D.
SRI. PAVANRAJ B.
SRI. PRASAD K.S.S.CH.
SRI. PULYA NAIK M.
SRI. RAJENDAR S.
SRI. RAMA KRISHNA K.V.S.
SRI. RAMA KRISHNA M.
SRI. RAMESH N.
SRI. RAMULU P.
SRI. RAMULU K.
SRI. ROHINI KUMAR D.B.
SRI. SATYADEV G.
MS. SHAILAJA S.
SRI. SRINIVAS B.
MRS. SWAPNA V.
MS. SWARAJYA LAKSHMI V.V.
MS. SWARNA LATHA CH.
MS. SWARNALATHA Y.
MS. VIJAY MARY A.
SRI. VIJAYAKUMAR K.
MS. ZEHRA ALI MS.
MS. A.V.L. SUBHADRA
TECHNICIAN ASST. GR.VII (GR.I)
SRI. BALAIAH K. / ELLAIAH
SRI. ACHAIAH/ PENTAIAH
SRI. ASHOK G/ MANKAIAH
SRI. BABU RAO P/ ACHIAH
SRI. BADIUDDIN
SRI. BALAIAH G/ JANGAIAH
SRI. BALRAJ B/ POCHAIAH
SRI. BIKSHAPATHI G/ BALAIAH
SRI. BIKSHAPATHI/ NARASIMHA
SRI. CHENNAYYA B.
SRI. DARSHAN B/ AGAIAH
SRI. DASARATH J.
SRI. M. SHABBIR ALI
SRI. M.A. RASHEED
SRI. DASHRATH D.
SRI. DEVASHAYYAM
SRI. EASHWAR/ ELLAIAH N.
109
MS. G. YENKAMMA / MOGLIAH
MS. GANGAMMA R.
SRI. GEORGE ANTHONY DAS
MS. GHOUSIA BEE/ BASHEERU
SRI. GHOUSUDDIN JAFFAR
SRI. HUSSAIN S.K./ AFZAL S.K.
SRI. ISMAIL KHAN/ KAREEM
SRI. JAHANGIR S/ SD. AHMED
SRI. JANGAIAH M/ BABAIAH
MS. KAREEMUNISA BEGUM
SRI. KRISHNA B/ MAISHIAH
SRI. KRISHNA B/ SATHAIAH B.
MS. LAKSHMI P/ NARASIMHA
SRI. MAISAIAH B/ LAKSHMAIAH
SRI. MAISIAH K/ ACHAIAH
SRI. MALLAIAH B/ CHENNAIAH
SRI. MALLESH A/ BALAIAH
SRI. MALLESH B/ GANDAIAH
SRI. MALLESH S/ RAMAIAH
MS. MANIKYAMMA N.
SRI. MIRZA MD. BAIG/ MORAD
SRI. MOHAN RAO P/ SWAMY
SRI. MOHD. GHOUSE/ SHARFUDDIN
SRI. MOHD. HUSSAIN
SRI. MOHD. IQBAL / MD. YAKOOB
SRI. YADAGIRI / BABAIAH
SRI. N. YADAGIRI / RAJAIAH
SRI. MOHD. JAFFAR
SRI. MOHD. KHAN / ISMAIL KHAN
SRI. MOHD. MAQBOOL
SRI. MOHD. NASIRUDDIN
SRI. MOHD. YOUSUF/ GALIB MOHD.
SRI. MOHD. YOUSUF/ ISMAIL MOHD.
SRI. MUMILL M.A/ M.A.HAI
SRI. MUMTAZ AHMED
SRI. NAGAIAH/ KISHTAIAH K.
SRI. NARASIMHA CHARI G.
SRI. NARASIMHA K/ BALAIAH K.
SRI. NARSING RAO K.
SRI. NARSING RAO T/ KUMARAIAH
SRI. NISAR HUSSAIN/ ABIDI
SRI. PANDU M/ MYSAIAH
SRI. POCHAIAH B/ ACHAIAH
SRI. N. YADAGIRI / ELLAIAH
SRI. A. YADAGIRI / KODAIAH
SRI. T.H. NARASIMHA
SRI. N. YADAGIRI / THIRUPAIAH
SRI. S. SHARFUDDIN
SRI. PARVATHULU / NARASIMHA
SRI. PRABHAKAR K.
SRI. RAJVEERAIAH A/ ISTARI
SRI. RAMSINGH/ KISHAN SINGH
SRI. RAMULU E/ POCHAIAH
SRI. RAMULU G/ NARASAIAH
SRI. RAMULU M/ CHANDRAIH M.
SRI. RAMULU K / MANKAIAH
SRI. RAMULU S/ DURGAIAH
SRI. RASHEED M.A./ S.K.KHAN
MS. RATNAMMA MS. D/ KRISHNA
SRI. RAVINDER C/ RAMASWAMY
SRI. SHAIK MUNEER / MAQDOOM
SRI. SAMSON B/ ISMAIL B.
SRI. SANDAIAH G/ PAPAIAH
SRI. SATHYANARAYANA G/ RAJU
SRI. SATHYANARAYANA K.
SRI. SATHYANARAYANA REDDY G.
MS. CH. VENKATARATNAM
SRI. G. VENKATESH / G. SWAMY
TECHNICIAN GR. II
(GR.I)
SRI. AZIZ PASHA
SRI. BHUPAL S.
MS. JAGADESWARI CH.
SRI. MAHESHWAR RAO R.
SRI. MEHARBAN SINGH S.
SRI. NARSING RAO N.
SRI. POCHAIAH B.
SRI. PRASAD P. L.
SRI. SATYANARAYANA
SRI. VENKATESHWARLU P.
SRI. ABDUL HAFEEZ
SRI. ALIMULLAH KHAN
MS. ANASUYA V.
SRI. ANTHAIAH D/ MAISAIAH
SRI. BABUL A.
SRI. BALAIAH A/ RAMASWAMY
SRI. BHIMLA/ LINGAIAH
MS. CHANDRAMMA S/ MALLAIAH
SRI. DAMODAR G.
SRI. ELLAIAH R./ RAMAIAH
SRI. FAREED AHMED S.
SRI. GAJULA SAI GANESH
SRI. GANESHWAR C.
SRI. GOPALAKRISHNA D.
SRI. HARISH CHANDER/ SOMULA
MS. M. SHUKLAMMA
SRI. H.K. HUSSAIN / AFZAL
MS. D. SHIVA PARVATHI
SRI. JAIKISHAN D/ NAGAIAH
SRI. KRISHNA
SRI. LAKSHMAN RAO M.
SRI. MADHUSUDAN RAO V.
SRI. MALLESH T/ RAJAIAH
MS. MANIAMMA MS. K.
MS. MEERABAI
SRI. MIRZA MOHD HABEEB
SRI. MOHD. AHEMED/ AKBAR
SRI. MOHD. AKBAR/ A.SUKOOR
SRI. MOHD. MOINUDDIN/
MD.JAFFAR
SRI. MOHD. ODUD/ MD.YOUNUS
MS. NARSAMMA D/ RAJAIAH
SRI. NARSING RAO N/ RAMULU
MS. NIRMALA MS. M.
SRI. OMPRAKASH K.
SRI. PANDU E/ RAMAIAH
SRI. PEDDULU B.
SRI. RAMAMURTY G.
SRI. G. SRIRAMULU / RAGAIAH
SRI. RAMJEE/ PARTHAIAH
SRI. SAIANNA G.
SRI. SD. MOINUDDIN/ SD
ASADULLA
SRI SHAIK DAWOOD
SRI. SUDERSHAN L/ BAGAYYA
MS. SUJATHA R.
SRI. SYED SHARIEF
SRI. SYED ABDUL KHADEER
SRI. SHAIK AHMED / MAHBOOB
SRI. SURENDER G.
SRI. SYED ALI RAZA
SRI. THREEMURTHULU S.
SRI. VENKATESHAM P
SRI. YADAGIRI T / BALAIAH
SRI. YADAGIRI A / RAMULU
SRI. YADAGIRI A / VENKAIAH
SRI. M. YADAIAH / POCHAIAH
SRI. YADAIAH D/ RAJALINGAIAH
MS. YADAMMA M/ PENTAIAH
SRI. YELLAIAH S./ BAGAIAH
SRI. ZAHEED HUSSAIN M
SRI. ABDUL HAFEEZ
SRI. SHAIK YOUSUF
SRI. R. ELLAIAH / RAMAIAH
Staff as on 01/ 04/ 2005
110
HELPER-B
SRI. MAHBOOB ALI
SRI. K.M. EASHWAR RAO
SRI. SALIM BIN MAHBOOB
SRI. D.ANTHAIAH / MAISAIAH
SRI. BHIMLA / LINGAIAH
SRI. KHAJA MOINUDDIN
SRI. ASADULLAH
SRI. T.MALLESH / RAJAIAH
SRI. V.P.SRINIVASA RAO
MS. M. ANASUYA / KRISHNA
MS. K. YELLAMMA
MS. K. GOKARAMMA
HELPER-A
SRI. J. VENKATESH
SRI. BHIKSHAPATHI T.
SRI. MUSHTAQ AHMED
SRI. RAMULU P.
SRI. RAMULU P.
SRI. SATYANARAYANA RAJU R
ADMINISTRATION
CONTROLLER OF ADMINISTRATION
SRI. RAKESH K. SHARMA
ADMINISTRATIVE OFFICER
SRI. N. PRAKASHAM
STORES & PURCHASE OFFICER
SRI. S. GNANAPRAKASAM
MS. B. SANDHYA RANI
FINANCE & ACCOUNTS OFFICER
SRI. M.R.K SASTRY
SRI. K.CHANDRASHEKAR
SECTION OFFICERS (G,F&A,S & P)
SRI. BINOD DUBEY
SRI. JAGANNADHA RAO R.L.V.
MS. JYOTHI RANI K
SRI. MURTHY DS
MS. SUDHA RANI P.
SRI. SUNIL KUMAR
SRI. V.VIDYA BHASKAR
SRI. M. ANANDA KUMAR
MRS. M.P. GEETHA
MRS. P.RAJYALAKSHMI
SRI. Y. SANYASI RAO
MS. T. MANOJA PRASAD
SRI. R. DEVARAJULU CHETTY
SRI. B. SRINIVAS
SRI. MAHIPAL SINGH
SR. HINDI OFFICER
MRS. V. SAILAJA GIRI RAO
HINDI OFFICER
DR. (MS) S. NASEEMA
SECURITY OFFICER
SRI. P.R. CHITNAVIS
PRIVATE SECRETARY
SRI. V.S.N. MURTHY
SRI. G. NARSING RAO
SRI. P.G.K. MURTHY
SRI. M. MALLIKARJUNA RAO
SRI. A. RAGHURAMAN
MRS. V.V. SUBBALAKSHMI
MRS. B. MALLIKAMBA
ASSISTANT GR I
(GEN. / F&A/ S&P)
SRI. GULAM MURTUZA
SRI. K.SEETHARAMAIAH
SRI. V.MUTHENDER
MRS. A. SITAMAHALAKSHMI DEVI
SRI. K.V.S.PRABHAKAR
SRI. P.VISHVESHWARA RAO
MRS. L.RATNA MANIKYAM
SRI. GYANENDRA PRASAD
SRI. N. RAMA RAO
SRI. S.N. MURTHY RAJU
SRI. Y.S.SHANKAR
SRI. M.A.SAJID KHAN
MRS. C.V.SREELATHA
SRI. M.ANNAJI RAO
SRI. V.KARUNAKAR
SRI. C.NARSING RAO
SRI. N.SHASHIKUMAR
MRS.SAYEEDA NASEEM BANU
MRS. T.ANNAPURNA
SRI. M.S. MURTHY
SRI. NEERAJ KUMAR
SRI. V. BASAVARAJU
SRI. B. RAJENDER KUMAR
SRI. B.C. SRINIVAS
SRI. N. ANAND
SRI. RAVI RAJALINGAM
SENIOR STENO (ACP)
SRI. G.B.S. MURTHY
SRI. V. NAGAMUNI
SRI. T. JAYARAJ
SRI. M. SUBBA RAO
SRI. D.V.V.R.K. ACHARYULU
SRI. V.V. RAMANA RAO
SRI. A.V. SRIHARI
MS. V. USHA
SENIOR STENO
SRI. I. JITHAMANMADHA RAO
SRI. V. MOHAN RAO
MRS. Y. SUJATHA
SRI. A. NAGESWARA RAO
MRS. N.N.S.S.V.B.T. SUNDARI
SRI. B. GNANESHWAR
SRI. ABDUL HAFEEZ
MRS. Y. MADHAVI
MRS. M. SAROJA
MRS. K. SESHALAKSHMI
MRS. M.S. SHASHIKALA
MRS. P. HARATHI JAWAHAR
SRI. Y. MURALIKRISHNA
MRS. N. SANJEEVA RANI
MRS. V. JAISHI RANI
SRI. R.R. YADU KRISHNA
MRS. M. SARITHA KUMARI
SRI. N.K. NAVEEN KUMAR
MRS. D. SHAMANTHA
SRI. D. KRISHNARAO
ASSISTANT GR II
(GEN. / F&A/ S&P)
SRI. VEERA PRAKASH
SRI. T.N. PRADHAN
SRI. Y.V. RAMESH
SRI. M. NARSING RAO
MRS. B. KOTESHWARI
SRI. R. SHESHI KUMAR
MRS. S.PRABHAVATHI
MRS. C.S.GEETHA
MRS. T.S. INDIRA
MRS. D.VENKATA LAKSHMI
MRS. S.HUSN AFROZE
SRI. P. RATAN RAJ
SRI. C. NATARAJU
MRS. G.V.LAKSHMI
MRS. A.UMA DEVI
111
SRI. S. KRISHNAIAH
SRI. P.SHANKER
SRI. K.YADAIAH
SRI. S.SHUJATH HUSSAIN
MS. D.UMA MAHESHWARI
SRI. K. SUDHAKAR
SRI. MOHD. ABDUL ZAFFAR
SRI. V.S.N. MURTHY
MRS. S. SAI BHAVANI
MRS. C. ANNAPURNA
ASSISTANT GR III
(GEN. / F&A/ S&P)
SRI. C. SATYASEELAN
SRI. A. VENKATESWARA RAO
SRI. A. SHIV SHANKAR
MISS. SUNITA DEVI
SRI. VINCENT THOMAS
MRS. J. SARASWATHI
MRS. R.A. KALAIMATHI
MS. J. LATHA
SRI. V.GANESH
SRI. M. NAGA RAJU
JUNIOR STENO
MRS. N. LAKSHMI SUNITHA
MISS. K.L. KAVITHA
SRI. G. SAINADH
SRI. SHIV SHANKAR KUMAR
SRI.S. REVATHI KUMAR
MS. T. RAMA DEVI
SECURITY ASSISTANT GR. VII
SRI. P. SUDERSAN
RECEPTIONIST
MS. USHA A.
SECURITY ASSISTANT GR. II
SRI. K. VEERAIAH
SRI. LAXMAIAH / MALLAIAH
SRI. K. YADAIAH / LAXMAIAH
COOK (GUEST HOUSE)
SRI. P. SHASHI NAIR
SRI. M. MOHAN RAO
RECORD KEEPER
SRI. L.B. SURYA PRAKASH
SECURITY GUARD (ACP)
SRI. PREM SINGH
SRI. M.D. KHALID ALI
SECURITY GUARD
SRI BH.V.GOPALKRISHNA
SRI. P. APPA RAO
SRI. T. S. NEEDHI
SRI. M. MADAN
SRI. D. SHIVARAMUDU
SRI K. NARSINGAPPA
SRI. T. KRUPPAIAH
SRI. P.S. PANICKER
SRI. A. BAL NARSIMHA
SRI. B. CHINNA
SRI. PRASAD LIMBO
SRI. K. SOMI NAIDU
SRI. G. MADHAVA REDDY
SRI. M. BALARAJU
SRI. T. VENKAT RAO
SRI. D. JAMES PAUL
SRI. S. TRINADHA RAO
SRI. P. ANANDA RAO
SRI. K.P. THAPA
OTHER STAFF
MS. Y. LAKSHMI DEVI
MS. ASGHARI BANU
SRI. G. CHANDRASHEKAR
MS. SUNDARI KAUR
MS. B. KALPANA
SRI. MD. YOUSUF/ ISMAIL KHAN
SRI. SHAIK ISMAIL/ AFZAL
SRI. K. RAMESH
MS. POCHAMMA / K. YADAIAH
SRI. MIR MUMTAZ ALI
SRI. S. CHITTAIAH
MRS. K.C. YESUPADAMMA
MRS. J. LAXMI
MRS. RENI BAI
MS. SYEEDA SIRAJUNNISA BEGUM
SRI. GHULAM TAHER
SRI. RAZAK ALI/ SADIQ ALI
MRS. U. SATYAMMA
SRI. P. VENKATESHAM
SRI. P. KRISHNA
SRI. HAFEEZ
SRI. P. SANGEETA RAO
SRI. SHAIK JAHANGIR
SRI. J. LEWIS
MRS. S. SWARNALATHA
SRI. PARUSHAIAH
MRS. A. SHASHIKALA
SRI. M. NARSIMHA S/ O MUTHIAH
SRI. R. NARSIMHA S/ O R. SWAMY
SRI. D. LAXMAIAH
MS. M. DEVAMMA
MS. P. RAMULAMMA
MRS. R. LAXMI W/ O SUDARSAN
MRS. S. POCHAMMA W/ O S.
SRI. MALLESH
MRS. P. RENUKA W/ O P.N. KUMAR
MRS. P. LAXMI W/ O T.B. NARASIMHA
MRS. M. LAXMAMMA W/ O RAMULU
SRI RAMULU S/ O SARAVAIAH
SRI. O. LAXMAIAH S/ O LACHAIAH
MRS. G. VENKATAMMA
SRI. A. VENKANNA
SRI. D. MANKIAH
SRI. N. KRISHNA
MS. P. YADAMMA
MS. CH. NARSAMMA
SRI. PANDARI
SRI. NARSING RAO C.K.
SRI. VENKATESH
SRI. M. SURYANARAYANA
SRI. B. MAHENDER
SRI. B. SURESH KUMAR
SRI. P. RAJAIAH
SRI. K. VAMAN RAO
SRI. K. SATYANARAYANA
SRI. M. DASARATH
SRI. NARENDAR. V
SRI. BALAIAH M
MS. NAGAMANI. C
SRI. SHABUDDIN MD.
Staff as on 01/ 04/ 2005
112
DISTINGUISHED OVERSEAS VISITORS DISTINGUISHED OVERSEAS VISITORS DISTINGUISHED OVERSEAS VISITORS DISTINGUISHED OVERSEAS VISITORS DISTINGUISHED OVERSEAS VISITORS
2004-05 2004-05 2004-05 2004-05 2004-05
* Dr Bong Yong Lee, Chi ef Sci ent i f i c Of f i cer and
Dr S J Choi , f rom Daewoong Pharmaceut i cal Co,
Sout h Korea
* Dr Crai g M Kni ght , Regi onal Busi ness Manager
f rom East man Chemi cal Co, USA
* Dr Wang Ji n Xu, General Manager and Dr Serene
On g , Bu si n ess Devel op men t Execu t i ve f r om
NIPSEA Technol ogi es, Si ngapore
* Dr Inder Jaggi , CEO f rom Novakos Corporat i on,
USA
Business Delegat ions from:
* DOW Chemi cal Int ernat i onal , USA
* Shi zi azhung Pharamaceut i cal Co, Si ngapore
* At l ant a Pharma Pvt Lt d
* Innocent i ve, USA
* VCCS Sdn Bhd, Mal ayasi a
* D&O pharmachem, USA
* St rem Chemi cal s, USA
2003-04 2003-04 2003-04 2003-04 2003-04
* St rem Chemi cal s, USA
* Dr Geor g e Fr aser, Head , Fr ag r an ce Resear ch
f rom Gi vuadan, Swi t zerl and
* Dr Masami , Inada, Presi dent , Ai si n Cosmos R&D
Co Lt d., Japan
Business Delegat ions from:
* Merck, USA
* Uquifa, Spain
* PPG Inc.,. USA
* P&G, USA
* Kansai Pai nt s, Japan
* Honeywel l Speci al i t i es, USA
* At l ant a, USA
* East man Chemi cal Co, USA
* Eli Lilly, USA
Prof. Shirakawa, Nobel Laureate from Japan (Centre) is seen
with Dr. J.S. Yadav, Director
Director IICT (left) with members of the French Delegation
Director IICT is presenting a plaque to a Pakistan Scientist
who visited IICT.
113
114
Blank
115
Aisin Cosmos R&D Co Lt d, Japan New funct ional mat erials
Glaxo Smit hKline Beecham, UK Hi gh t hroughput synt hesi s
Confluent Surgicals, USA Drug delivery
Givaudan, Swit zerland New Processes
DuPont , USA Focussed compound l i brary Devel opment
Kansai Paint s, Japan Process for phot o acid generat or
NATIONAL PROJECTS
Minist ry of Agricult ure, New Delhi PHT in oilseeds & pulses
NMITLI, CSIR, New Delhi Funct i onal i zat i on of al kanes
Minist ry of Science & Technology, New Delhi Field evaluat ion & demonst rat ion of
pheromones
NMITLI, CSIR, New Delhi Dicarboxylic acids
Direct orat e of Rice Research (ICAR), Genet ic enhancement of aromat ic short
Hyderabad grain rice for higher product ivit y & export
Neul and Laborat ori es Lt d., Hyderabad Process knowhow for met hane
sulfonic acid from mercapt an
effluent generat ed in Ranit idine
Manuf act ure
DBT, New Delhi Field evaluat ion of pheromones
demonst rat i on
Minist ry of Healt h & Family Welfare, Use of modern t echnology &
New Delhi biot echnology in Ayurveda, Siddha,
Unani & Homeopat hy drugs development
Muez-Hest Process Technologies (P) Lt d., Enzymat ic degumming & dewaxing of
Mumbai/ Ramcharan Oil Indust ries, Hyd. rice bran oil
Muez-Hest / Process Technologies, Mumbai/ Enzymat ic degumming & dewaxing of
Bhat inda Chemicals Lt d., Bhat inda. rice bran oil
Mecpro Heavy Engg. Lt d. N. Delhi/ Saraiwala Agro Enzymat ic degumming & dewaxing of
Refineries Limit ed, Hyderabad rice bran oil
NEW CONTRACTS SIGNED/ ASSIGNMENTS UNDERTAKEN NEW CONTRACTS SIGNED/ ASSIGNMENTS UNDERTAKEN NEW CONTRACTS SIGNED/ ASSIGNMENTS UNDERTAKEN NEW CONTRACTS SIGNED/ ASSIGNMENTS UNDERTAKEN NEW CONTRACTS SIGNED/ ASSIGNMENTS UNDERTAKEN
(2003-05) (2003-05) (2003-05) (2003-05) (2003-05)
OVERSEAS PROJECTS
PARTY PROJECT
NEW CONTRACTS SIGNED/ ASSIGNMENTS UNDERTAKEN NEW CONTRACTS SIGNED/ ASSIGNMENTS UNDERTAKEN NEW CONTRACTS SIGNED/ ASSIGNMENTS UNDERTAKEN NEW CONTRACTS SIGNED/ ASSIGNMENTS UNDERTAKEN NEW CONTRACTS SIGNED/ ASSIGNMENTS UNDERTAKEN
116
Mect ech Process Engg. Pvt . Lt d, New Delhi Enzymat ic degumming & dewaxing of
rice bran oil
Anus Laborat or i es, Hyderabad Process rout e opt imizat ion for 4
i nt ermedi at es
Isaagro (Asia) Agro Chemicals Pvt . Lt d., Field t rial efficiency of Elofenprox 20%
Mumbai W/ P on larva & adult A. St ephensi
Bharat Elect ronics Lt d, Bangalore Det oxificat ion & neut ralizat ion of various
gas cylinders of BEL at Bangalore
KCP Biot ech Lt d. Hyderabad Engg. services for set t ing up a
commercial plant t o manufact ure
t urmeric, chillies & annat t o
Unit ed Insurance Lt d., Hyderabad Chemical report on fire accident of M/ s
Roopa Indust ri es Lt d.
Precision Elect ronic Component s Mfg. Co. Providing assist ance in developing t he
Hyderabad fi re ret ardant coat i ngs
DRDL, Hyderabad Special Grade Epoxy Novalac syst em
suit able for canist er (PJ-10) applicat ion
Raj shree Sugars & Chemicals Lt d, Development of process knowhow for
Coi mbat ore t wo pheromone Chemicals
Sami Labs Lt d, Bangalore Development of process knowhow for
Sol anesol (98%) Decaprenol & Co-
Enzyme Q-10
Alfa Laval (India) Lt d, Pune / Sarda Agro Oils Lt d Enzymat ic degumming & dewaxing of
rice bran oil
Mecpro Heavy Engg. Lt d., New Delhi/ Enzymat ic degumming & dewaxing
AP Organic Oils Pvt . Lt d, of rice bran oil
Mit t al Musli Farms & Research Cent re, Charact erizat ion of ext ract of safed
Hyderabad musl i
Balmer & Lawrie Lt d, Chennai Consult ancy on R&D aspect s of
Lipid Science &Tech proj ect s of int erest
PARTY PROJECT
117
Hindust an Reserch Cent re, Mumbai Collect ion of explosion on t est s dat a for
t he given 5 samples
The Andhra Sugars Lt d, Kovvur REIA st udy for t he const ruct ion of
secured land fill at mercury based caust ic
soda pl ant
HAL, Bangal ore Supply of low loss polyst er resin &
benzoyl peroxide
Navin Fluorine Indust ries Lt d, Mumbai Process knowhow for 2,2,2-Trifluoro
Et hanol on lab scale
Saket Biot echnologies Lt d, Hyderabad Explorat ory st udies for novel drug
delivery syst em for newer moiet y
The Andhra sugars Lt d, Kovvur Risk analysis of HAZOP st udy of UDMH
plant at Tanuku, AP
Nicholas Piramal India Lt d, Hyderabad Process knowhow for coenzyme Q-10
Glampt ech Agro Process Pvt . Lt d, Mumbai Process knowhow for enzymat ic
degumming & dewaxing of rice bran oil
Tripura Biot ech Lt d., Hyderabad Development of process knowhow
for five product s
Novozymes Sout h Asia (P) Lt d, Preparat i on of t rans-f ree vanaspat hi
using enzymat ic int erest erificat ion of
veget able mixt ure
Hermes Chemicals Co. Pvt . Lt d, Secunderabad Samples of Toprimat e
Kiran Adhesives & Chemicals, Adhesives for aut omat ic labeling
Hyderabad machi nes
Godavari Sugar Mills Lt d., Mumbai Biocryst al demonst rat ion on 20,000 KL
react or
K N Agri Biot ech, Hyderabad Bi ocompat i bl e pol ymer membrane for
cont rol rel ease appl i cat i ons
DST, New Delhi Implement at ion of Indo-Sout h African
Joint Proj ect
PARTY PROJECT
New Contracts Signed/ Assignments Undertaken
118
Bharat Rasayan Lt d, New Delhi Licensing of knowhow for Esfenvalerat e (t ech)
Vinat i Organics Lt d, Mumbai Value addit ion for N-but ylbenzene by
preparat i on of four i nt ermedi at es
Krebbs Bi ochemicals Lt d, Hyderabad Preparat ion and providing 5 gms sample
of Di hydro Lovast i n
DST, New Delhi Synt hesis and development of new
biodegradable and biocompat ible
Pol ymers for t i ssue cont act i ng
appl i cat i ons
Rhizome Dist illeries (P) Lt d, Hyderabad Est ablising and validat ing QC Laborat ory
Biological (E) Lt d., Hyderabad Acut e, Sub-acut e chronic t oxicit y
st udies of haemophiles t ype-b conj ugat e vaccine
in different animal model
Cent re for Excellence in Polymer Science, Fabricat ion of membranes for conduct ing
Karnat aka Uni versi t y, Dhar wad R&D St udies in specialit y, organic
coat ings and polymer areas
Hindust an Lever Lt d, Mumbai SEP-Box service charges for analysis of
client samples
Ganapat hi Solvex (P) Lt d, Process knowhow for enzymat ic
degumming and dewaxing of rice bran oil
Bagari a Agro Product s, Aurangabad Process knowhow for enzymat ic
degumming and dewaxing of rice bran oil
Jubi l i ant Organosys Lt d, Mysore AZM proj ect work
Amchem Product s Lt d, Noida Accelerat ing weat hering t est and salt
spray cl i ent
Jayshree Indust ries (P) Lt d, Chhat t isgarh/ Process knowhow for enzymat ic
Mecpro Heavy Engg. Lt d, New Delhi degumming and dewaxing of rice bran oil
PARTY PROJECT
119
TMOP & M, New Delhi Pilot plant scale process for biodiesel
from high FFA veget able oils and acid oil
TMOP & M, New Delhi Cont rolled release polymer devices for
pest management i n groundnut st orage
TMOP & M, New Delhi Cycl odext ri nes as sensors
Balmer Lawrie & Co Lt d, Chennai Process knowhow for t wo formulat ions
equivalent t o a) B 101 high performance
Rat iquor and (b) B 102 a premium segment
fish oil Rat iquor
DBT/ CSIR-IICT & Govt . of AP Bi ot echnol ogy Incubat or Cent re
Raj shree Sugars & Chemicals Lt d, Synt hesizing & providing 200 gms of
Coi mbat ore pheromone mi xt ure
Indigene Pharmaceut icals Pvt . Lt d, Development of novel bioact ive
Hyderabad from plant mat erials & ext ract s in t he
t herapeut ic molecules area of ant i
cancer drugs
Gland Pharma Lt d., Hyderabad To provide R&D solut ions in NMR
t echni ques
CFEES (DRDO), New Delhi Development of process knowhow for
Hept a f l uoropropane
AP Pollut ion Cont rol Board, Hyderabad St udy on wat er consumpt ion and wast e
wat er generat ion in M/ s. Mahalaxmi Text -
Print s Pvt . Lt d., Madanapally (V), R.R.
Di st .
PEG Consult ant s & Engineers Pvt . Lt d, Process knowhow for enzymat ic
Mumbai degumming and dewaxing of rice bran oil
on 50 TPD scale
BHEL, Hyderabad Engineering of base frame & mechanic
mount ed piping for indust rial t urbines
NIMITLI/ CSIR, New Delhi Development of Novel fungicides
PARTY PROJECT
120
SMS pharmaceut icals Lt d, Hyderabad Development of process knowhow for
t wo int ermediat es : a) Dilt iazem HCl by
asymmet ric synt resis and b) Taxol C-13
side chain (API Int ermediat e)
Cent ral Silk Board, Bangalore St udies on ut ilizat ion of Erisilk worm
pupae by ext ract ion of oil from pupae
and prepupae
Cent ral Silk Board, Bangalore St udies on ut ilizat ion of Erisilk
worm pupae by ext ract ion of surface
waxes from pupae and prepupae
Zenenpep Biot echnologies, Hyderabad Toxicological st udies on efficacy and
safet y i n vi vo experiment s on t heir
propri et ary pept i de mol ecul e
used for t reat ment of wounds and burns
INGA Pharmaceut icals, Mumbai Synt hesis of R-S-Noscapine
The Andhra Sugars Lt d, AP To conduct st udies on improvement of
aspirin react ion and plant
Tarak Chemicals Pvt . Lt d., Guj arat Development of zinc di acrylat e
NOCIL, Mumbai Development of process and suit able
cat alyst for react ion of Aniline wit h Para-
Nit ro-Chlorobenzene (PNCB) t o give 4-
Nit ro-Diphenylamine (4NDPA)
and subsequent reduct ion t o 4-Amino
diphenylamine (4-ADPA) (99.8% puri t y)
Tribal Welfare Dept ., Hyderabad Prot ect ion of communit y & t radit ional
knowledge relat ing t o plant s and
medicines wit h STs of AP
DST / IICT/ Virchow Chemicals Lt d, First preclinical invest igat ion in India on Hyderabad
non viral gene t herapy of chronic wounds
DST / IICT/ Indian Medicines & Qualit y assurance and validat ion of some
Pharmaceut ical Corporat ion Lt d, Mohan ayurvedic formulat ions for lifest yle relat ed
and gyneacol ogi cal di sorders
PARTY PROJECT
121
DART Manufact uring Co. Lt d, Hyderabad Ident ificat ion of fungus at t acking product
& suggest ion of suit able remedial measures
CMPDI, Ranchi Direct sourcing of coal for value added
Chemicals
Rayudu Laborat ories (P) Lt d, Hyderabad Technology for Indelible ink
Recon Oil Indust ries (P) Lt d, Mumbai Evaluat ion of blended edible oils
The Andhra Sugars Lt d, Kovvur, AP To prepare REIA report for t he
conversion of mercury cell membrane
t echnology for caust ic pot ash product
Apot hecaries Lt d, New Delhi Met hod development for t he quant isat ion
of Acomprosat e in plasma samples
RR Indust ries, Hyderabad To carry out paint erosion t est as per MIL
specificat ions of t wo pair of paint sampl es
Reliance Life Sciences (P) Lt d, Mumbai Providing pilot plant facilit ies and
t echnical services
Virchow Chemicals Lt d, Hyderabad Evaluat ion & cert ificat ion of wast e wat er
recycling syst em in t he product ion of
Acet yl Phanilyl Chloride
Si va Kishore Sevashram, Tenali. Solvent solut ion for manufact ure of wool
pol i sh
Bhagiradha Chemicals, Hyderabad St andardizat ion of impurit ies in
chl orpyri phos t echni cal
MSPL, Hospet To fire t he given samples at 1350
o
C,
1450
o
C and 1500
o
C
Sat yam Comput er Services Lt d, Hyderabad Providing t echnical consult ancy and
undert aki ng anal yt i cal and t est i ng
services for evaluat ion of samples
Bharat Rasayan Lt d, New Delhi Demonst rat i on of Esfenval erat e ( Tech.)
process on 50 gm scale
Virchow Chemicals Lt d, Hyderabad Licensing of Esfenvalerat e ( Tech.) on
scale of 2 Kg product
PARTY PROJECT
122
Myt hri Agro Indust ries, Kerala Process knowhow for biopest icide
f ormul at i ons f rom neem seeds/ kernel s
AP Geet a Parsrami ka Sahakara Art hi k Spray drying of Neera sample
Sankshema Samst ha, Hyderabad
Vishnu chemicals (P) Lt d, Hyderabad Ut ilizing facilit ies at Pilot Plant -II
Saraca Laborat ori es Lt d, Hyderabad Ut i l i zing facilit ies at Pilot Plant -II
Oil & Nat ural Gas Corporat ion Lt d, Reliabilit y st udy of crit ical cont rol and
Inst it ut e of Engineering and Ocean saf et y syst em
Technology, Mumbai
Oil & Nat ural Gas Corporat ion Lt d, Development of failure frequency dat a
Inst it ut e of Engineering and Ocean base for ONGC offshore process
Technology, Mumbai equi pment
DBT, New Delhi Hydrogen product ion by anaerobic
t reat ment process f rom ef f l uent s
Minist ry of Informat ion Technology, New Delhi Development of an int egrat ed informat ion
syst em for t he cont rol of Bancroft ian
filariasis in Andhra Pradesh
DST, New Delhi Cont rol of Malaria t hrough Int egrat ed
Inf ormat ion Technology t ools in
Arunachal Pradesh
DBT, New Delhi Int egrat ed cont rol of Filariasis and
Malaria t hrough Decision Support
Syst em (BTIS net work programme)
in Andhra Pradesh
DST, New Delhi Super capacit ors based on conduct ing
polymers An energy st orage device
DST, New Delhi St andardizat ion of hi-frequency plant
regenerat ion from different explant s of
Chl orophyt um bori vi l i anum, an i mport ant
medicinal plant of India
TMOP&M, New Delhi Post harvest prot ect ion of maize from
pest s and diseases in Sout hern India
PARTY PROJECT
123
CMPDI, Ranchi Direct sourcing of coal for value added
chemicals (in collaborat ion wit h CFRI)
DST, New Del hi Enzyme medi at ed resol ut i ons and
deracemizat ions in ionic liquids
MNES, New Delhi Solar hydrogen product ion from wat er for
fuel cell
DST, New Delhi Boyscot fellowship programme in t he
area of het ero-geneous cat alysis t o be
held at Lehigh Universit y, Bet hlehem,
Pennsylvania, USA for a durat ion of 12
mont hs
Raj ashree Sugars Lt d, Process for pheromone chemicals used
Coi mbat ore in IPM for sugarcane crop pest s
Anus Laborat or i es Lt d, Process for 4-Vinyl aniline
Hyderabad
Shri Arihant Pet rochem (P) Lt d, Process knowhow for Hydrogenat ion of
Bangal ore crude rice bran wax
Abhay Solvent s (P) Lt d, Knowhow for enzymat ic process for
Koppal , Karnat aka degumming of rice bran oil
Kamal Solvent Ext ract ions (P) Knowhow for enzymat ic process for
Lt d., Raj nandgaon degumming of rice bran oil
Chemi cal Const ruct i on
Int ernat ional Pvt . New Delhi (Proj ect Engg. Co.)
Jay Shree Solvex (I) Pvt . Lt d, Durg, Chhat t ishgarh Knowhow for enzymat ic process for degumming
Mecpro Heavy Engg. Lt d., New Delhi of rice bran oil
(Proj ect Engg. Co.)
SMS Pharmaceut icals Lt d, PC based real t ime process cont rol
Hyderabad t echnology for aut omat ion & cont rol of
NMSM (Ranit idine Int ermediat e)
format i on react or of Rani t i di ne
product i on process
PARTY PROJECT
124
The Godavari Sugar Mills Lt d, Sameerwadi Alcohol product ion using free yeast and
yeast cryst als in modified bioreact or
VSSC, Trivandrum Synt hesis of comput at ional design of
macrocyclic ligands on process for
separat ion of hafnium from
zirconium t ailings by molecular
recogni t i on t echnol ogy
Consolidat ed Fibres, Kolkat a Ext ract ion of impurit y-free sodium
t hi ocyanat e (Nanofi l t rat i on Technol ogy)
Vinat i Organics Lt d, Mumbai Process for one-pot conversin of N-
But ylbenzene (NBB) (92%) a
byproduct t o value added int ermediat e 1-
phenyl but alamine (PBA) (98%)
Sanmar Specialit y Chemicals Lt d., Bench-scale process for Hydrazine
Chennai Hydrat e (ket azi ne rout e)
Dabur Research Foundat i on, New Ant i -cancer compounds synt hesi s
Ghazi abad
NMITLI, CSIR, New Delhi HERBOPRINT Chromat ographi c
fingerprint ing of herbal based
preparat i ons f or degenerat i ve
di sorders
NMITLI, CSIR, New Delhi A novel chromat ographic finger print ing
met hod for chemical and t herapeut ic
st andardi zat i on of food
IFCPAR (Indo-French Novel synt het ic met hodologies in
Cooperat ion), New Delhi combinat orial chemist ry for t he
preparat ion of bioact ive molecules
VSSC, Ti ruvanant hapuram Preparat ion of 4,4
-
met hylene bis
Kerel a (cyclohexylamine) a solid propellant
generat ed from 4,4
-
met ylene-dianiline
(MDA)
PARTY PROJECT
125
IFCPAR (Indo-French Development of t oxic wat er pollut ion by
Cooperat ion), New Delhi advanced oxidat ion process.
Gas Aut horit y of India Lt d, New Delhi Pre-commercializat ion st udies of ANG
t echnol ogy
Aeronaut i cal Devel opment Synt hesis & development of cyanat e
Aut hori t y, Bangal ore est er based resins for advanced aircraft
appl i cat i ons
Indian Oil Corporat ion, The possible ill-effect s over exposure of
Fari dabad popul at i on t o exhaust emi ssi on
Mit t al Musli Farm & Research Subacut e t oxicit y st udy of safed musli in
& Swiss Cent re, Maharasht ra wist ar rat s mice
Tablet s India Lt d, Chennai Evaluat ion of DSA-5 for ant idiabet ic
act ivit y in rat s
Relisys Medical Devices Lt d, Est imat in on paclit axel release from
Hyderabad coat ed st ent s
Lyka Labs Lt d, Mumbai Rabeprazole inj ect ion-A 14 day
int ravenoust oxicit y st udy in mice and rat s
Kol hapur Muni ci pal Corporat i on, Bi ological cont rol of wat er hyacint h at
Maharasht ra Rankala, lake
SPIC, Tut icorin Engineering design for 500 TPA
pyrazi nami de pl ant
Pidilit e Indust ries Knowhow on bench scale process for
Mumbai hydroxy et hyl cellulose
DBT, New Delhi Development of high performance
biological fluidized react or for ant i-biot ic
product i on
Gas Aut horit y of India Lt d, New Del hi Set t i ng up nat ural gas l aborat ory
Nat co Pharma Lt d, Hyderabad Development of pilot level anerobic
react or for t he Treat ment of
pharmaceut i cal wast e
PARTY PROJECT
126
MNES, New Delhi Advanced Bi omass Gasi f i cat i on
IFCPAR, New Delhi (Indo- Novel synt het ic met hodologies in French
col l aborat i on proj ect ) combi nat ori al chemi st ry for t he
preparat ion of bioact ive molecules
l i brari es
Dart Manufact uring (P) Lt d, Designing novel liposomal gene delivery
Hyderabad reagent s & invest igat ing t he
role of size & surface change of lipid-DNA
V Life Sciences Technologies Ant i -i nfl ammat ory pot ent i al of synt het i c
Pvt . Lt d., Pune compounds in rat paw edema model
DST, New Delhi Design, Synt hesis & evaluat ion of
Nonl i near Opt ical Propert ies of New
DelhiNovel Organic & Met alic Molecular
Mat eri al s
MSN Laborat ories Lt d, Sub-acut e Toxicit y st udy of Ezet imibe
Hyderabad and Resuvast at in calcium in Mice and
Rat s
DBT, New Delhi Product ion of Alkaline Prot eases by using
Immobi l i zed Baci l l us Li cheni f ormi s i n
st irred t ank and zed bed React ors
DST, New Delhi Signal Chemicals in Plant s during
Nodul at i on
DST, New Delhi Process and product st andardizat ion of
classical ayurvedic drugs wit h special
reference t o rheumat i sm
DST, New Delhi Designing novel liposomal gene delivery
reagent s & invest igat ing t he role of size &
surface change of lipid-DNA complex in
liposomal gene delivery
PARTY PROJECT
127
X-Ray Studies on Drug Molecules for Industries
O Sandoz Pvt . Lt d, Thane
O Mat ri x Laborat ori es Lt d, Hyderabad
O Jubi l i ant Organosys Lt d, Mysore
O Torrent Pharmaceut i cal s Lt d, Guj arat
O Lupin Lt d., Pune
O IPCA Laborat ories Lt d., Mumbai
O USV Lt d., Mumbai
O Cadila Pharmaceut icals Lt d., Ahmedabad
O In d - Sw i f t Lab o r at o r i es Lt d ., Bh ag w an p u r
(Punj ab)
O Dabur Research Foundat i on Lt d., Ghazi abad
(UP)
O Emcure Pharmaceut icals Lt d., Pune
Hazop, Risk and EIA Studies for industries
O Bayer India Lt d, Mumbai
O Wonder Gas India Lt d, Hyderabad
O Unit ed Chemicals, Hyderabad
O Ana Bond India, Chennai
O Bhart h Pet roleum Corporat ion Lt d, Chennai
O Indian Oil Corporat ion Lt d, Ahmedabad
O Hindust an Lever Research Cent re, Mumbai
O Andhra Sugars Lt d, Tanuku, AP
O Hi n d u st an Pet r o l eu m Co r p o r at i o n Lt d ,
Vi sakhapat nam
O Minist ry of Environment and Forest s, New Delhi
O IBB Co. Lt d, Cherlapally, Hyderabad
O Coromandel Fer t i l i zers Lt d, Vi sakhapat nam
Advisory Consutancy Services rendered to industry:
O Dabur India Lt d, Ghaziabad, UP
O Balmer & Lawrie Co. Lt d., Chennai
O Alkali Met als Lt d, Hyderabad
O AVRA Laborat ori es (P) Li mi t ed, Hyderabad
O Indigene Pharaceut icals Lt d, Hyderabad
O Indus Biosciences (P) Lt d, Hyderabad
O Gland Pharma Lt d, Hyderabad
O Max Bond, Bangalore
O USV Lt d, Mumbai
O Bezwada Biomedical Co. Lt d, Secunderabad
O Ogene Syst ems India (P) Lt d, Hyderabad
O Supreme Chemical Vent ures (P) Lt d, Hyderabad
O Rallis India Lt d, Rallis Research Cent re, Bangalore
O Alchem Int ernat ional Lt d, New Delhi
O Orchid Chemicals & Pharmaceut icals Lt d, Chennai
O Ashian Herbex Lt d, Hyderabad
O Sai Life Sciences Lt d, Hyderabad
O Vishnu Chemicals Pvt . Lt d, Hyderabad
O Biological (E) Lt d, Hyderabad
O Sarracca Labs (P) Lt d, Hyderabad
Exchange of agreement with M/S. SMS Pharmaceuticals,
Hyderabad.
Natural colour extraction plant of M/S. KCP Biotech, Hyderabad.
128
TECHNOLOGIES / PROCESSES DEMONSTRATED TECHNOLOGIES / PROCESSES DEMONSTRATED TECHNOLOGIES / PROCESSES DEMONSTRATED TECHNOLOGIES / PROCESSES DEMONSTRATED TECHNOLOGIES / PROCESSES DEMONSTRATED
O Raj ashree Sugars Lt d, Process for Pheromone chemicals used in IPM for
Coi mbat ore sugarcane crop pest s
O Neuland Labs Lt d, Hyderabad Process knowhow for t he conversion of met hyl
mercapt an, an effluent gas, t o a value added
product (met hane sulphoic acid)
O Anus Laborat or i es Lt d, Process for 4-Vinyl aniline
Hyderabad
O Shri Arihant Pet rochem (P) Lt d, Process knowhow for Hydrogenat ion of Crude
Bangal ore Rice Bran wax
O Abhay Solvent s (P) Lt d, Process for enzymat ic process for degumming
Koppal , Karnat aka of rice bran oil on 50 TPD
O Saraiwala Agro Refineries Process for enzymat ic process for degumming
Lt d, Hyderabad of rice bran oil on 50 TPD
O Ramacharan Oi l Indust ri es, Process for enzymat ic process for degumming
Hyderabad of rice Bran oil on 50 TPD
O Kamal Solvent Ext ract ions (P) Process for enzymat ic process for degumming
Lt d., Raj nandgaon of ri ce bran oil on 50 TPD
O AP Organics Pvt Lt d, Dhuri, Process for enzymat ic process for degumming
Punj ab of rice bran oil on 50 TPD
O Jay Shree Solvex (I) Pvt . Lt d, Process for enzymat ic process for degumming
Durg, Chat t i shgarh of ri ce bran oil on 50 TPD
O SMS Pharmaceut icals Lt d, PC based real t ime process cont rol t echnology for
Hyderabad aut omat ion & cont rol of NMSM (Ranit idine
Int ermediat e) format ion React or of Ranit idine
product i on process
O The Godavari Sugar Mills Lt d, Alcohol product ion using free yeast and yeast
Sameerwadi cryst als in modified bioreact or
O Vinat i Organics Lt d, Mumbai Process for one-pot conversion of N-But ylbenzene
(NBB) (92%) a byproduct t o value added
int ermediat e 1-phenyl but alamine (PBA) (98%)
2003-04 2003-04 2003-04 2003-04 2003-04
PARTY PROJECT
129
2004-05 2004-05 2004-05 2004-05 2004-05
PARTY PROJECT
O Sarda Agro Oils Lt d., Pune Process for enzymat ic degumming and
dewaxing of rice bran oil on 50 TPD
O S.S.D. Oil Mills Co. Lt d., Process for enzymat ic degumming and
Chennai dewaxing of rice bran oil on 50 TPD.
O VSSC, Trivandrum Synt hesis of comput at ional design of
macrocyclic ligands on process for separat ion of
Hafnium from zirconium t ailings by molecular
recogni t i on t echnol ogy
O Consolidat ed Fibres, Kolkat a Ext ract ion of impurit y-free sodium Thiocyanat e
(Nanofi l t rat i on Technol ogy)
O Navi n Fl uori ne Indust ri es 2,2,2-Tri fl uoroet hanol
Mumbai
O SRF Lt d, New Delhi Pilot plant process on HFC-134a
O Navin Fluorine Indust ries, Pilot plant process on HFC-134a
Mumbai
O Sanmar Specialit y Chemicals Lt d., Bench-scale process for Hydrazine Hydrat e
Chennai (ket azi ne rout e)
O Dabur Research Foundat i on, New Ant i -cancer compounds synt hesi s
Ghazi abad
O NMITLI, CSIR, New Delhi HERBOPRINT Chromat ographic fingerprint ing
of herbal based preparat ions for degenerat ive
di sorders
O NMITLI, CSIR, New Delhi A novel chromat ographic finger print ing met hod
for chemical and t herapeut ic st andardizat ion of
f ood
O IFCPAR (Indo-French Novel synt het ic met hodologies in combi-
Cooperat ion), New Delhi nat orial chemist ry for t he preparat ion of bioact ive
mol ecul es
O Bharat Rasayani k Chemi cal s Process knowhow for Esfenvalerat e (chiral
Lt d., New Delhi synt het i c pyret hroi d)
TECHNOLOGIES / PROCESSES / REPORTS RELEASED TECHNOLOGIES / PROCESSES / REPORTS RELEASED TECHNOLOGIES / PROCESSES / REPORTS RELEASED TECHNOLOGIES / PROCESSES / REPORTS RELEASED TECHNOLOGIES / PROCESSES / REPORTS RELEASED
2003-04 2003-04 2003-04 2003-04 2003-04
PARTY PROJECT
Technologies / Processes Demonstrated
130
PARTY PROJECT
O Kansai Paint s, Japan Process for phot o acid generat or
O VSSC, Ti ruvanant hapuram Preparat ion of 4,4
-
met hylene bis
Kerel a (cyclohexylamine) a solid propellant generat ed
from 4,4
-
met ylene-dianiline (MDA)
O IFCPAR (Indo-French Development of t oxic wat er pollut ion by
Cooperat ion), New Delhi advanced oxidat ion process.
O Gas Aut horit y of India Lt d, Pre-commercializat ion st udies of ANG (Adsorbed)
New Delhi Nat ural Gas) t echnol ogy
O Aeronaut i cal Devel opment Synt hesis & development of cyanat e est er
Aut hori t y, Bangal ore based resins for advanced aircraft applicat ions
O Indian Oil Corporat ion, The possible ill-effect s over exposure of
Fari dabad popul at i on t o exhaust emi ssi on
O Mit t al Musli Farm & Research Subacut e t oxicit y st udy of safed musli in wist ar
Cent re, Maharasht ra rat s &mice
O Tablet s India Lt d, Chennai Evaluat ion of DSA-5 for ant idiabet ic act ivit y in
r at s
O Relisys Medical Devices Lt d, Est imat in on paclit axel release from coat ed
Hyderabad st ent s
O Lyka Labs Lt d, Mumbai Rabeprazole inj ect ion-A 14 day int ravenous
t oxicit y st udy in mice and rat s
O Kol hapur Muni ci pal Corporat ion, Biological cont rol of wat er hyacint h at Rankala
Maharasht ra l ake
O SPIC, Tut icorin Engineering design for 500 TPA pyrazinamide
pl ant
O Pidilit e Indust ries, Mumbai Knowhow on bench scale process for hydroxy
et hyl cellulose
O DBT, New Delhi Development of high performance biological
fluidized react or for ant i-biot ic product ion
O Gas Aut horit y of India Lt d, Set t i ng up nat ural gas l aborat ory
New Delhi
O Nat co Pharma Lt d, Hyderabad Development of pilot level anerobic react or for
t he Treat ment of pharmaceut ical wast e
O KCP Biot ech, Hyderabad Det ailed design report for 1 TPD (raw mat erial)
Commercial plant t o manufact ure t urmeric,
annat t o and chilies
131
PARTY PROJECT
O Saket Bi ot echnol ogi es Process knowhow for a herbal cream for
(P) Lt d., Hyderabad skin and cosmet ic applicat ion
O Kansai Paint s, Japan Sol der resi st mat eri al s
O MNES, New Delhi Development of a met hanol reformer cat alyst
for 10 W fuel cell
O DST, New Delhi Synt hesis of carbohydrat es based signal
chemicals for nodulat ion (in plant s)
O DST, New Delhi Designing efficient non-lionear opt ical
organic molecules A quant um Chemical
Approach
O DST, New Delhi Role of highly polarized / charge t ransfer
excit ed st at e-quant um chain isomerizat ion
O Technology Misson on Mat erials for posit ive phot o resist s
Elect ronics Mat erials (DOE)
Process Safet y Cent er has undert aken and submit t ed t he report on Risk Analysis and HAZOP
studies for following clients.
O BPCL-Mumbai Risk Analysis of proposed LPG bot t ling plant of
BPCL
O EPTRI-Hyderabad Mult ipat h Risk Analysis of Break Linings Plant
O IOCL-Ahmedabad Risk Analysis of Aut o LPG dispensing syst em at IOCL,
Vejalpur (Set elight ) Ahmedabad
O Wonder Gas India Limit ed, Risk Analysis of proposed hexane filling St at ion of
Kondapally, A.P Wonder Gas India Lt d., Kondapally
O Bayer India Limit ed, Consequence Analysis of Boilers, Rot ary Klin,Incinerat or
Thane, Mumbai and Aniline & Nit rogen St orages
O Bharat Pet roleum HAZOP St udies of proposed LPG t ransfer line from
Corporat ion Lt d., Hazira. ONGC t o Bot t ling Plant of BPCL, Haziara , Surat .
O BPCL, Chennai Risk Analysis of proposed LPG siding facilit y of BPCL,
at Cherlapally
O BPCL, Cherlapally, Risk Analysis of conversion of FO TO HSD St orage
Hyderabad and proposed MS, ATF, and Et hanol St orage Tanks of
BPCL, POL Depot at Cherlapally
Technologies/ Processes / Reports Released
132
O Bayer India Lt d., Consequence Analysis of PSCl
3
Met hyl Parat hion,
Thane, Mumbai. Met a Syst ox-R, CTA & Thiosalt React ors
O The Andhra Sugars HAZOP St udy and FTA, ETA of HTPB Plant at
Limit ed, Tanuku, A.P. Tanuku
O Unit ed Chemicals Risk analysis of proposed pest icides t echnical and
Hyderabad formulat ion plant at Indriyala (V), Pochampally (M),
Nalgonda Dist A.P.
O IOCL-Cuddapah Damage cont ouring of ident ified hazardous scenarios
for LPG bot t ling plant , Cuddapah
O BPCL-Cherl apal l y Risk Analysis and HAZAOP st udies of proposed
LPG siding facilit y at Cherlapally
O Unilever Inida Limit ed, Explosion St udy Of Soap- Ipa- H
2
O
2
Mixt ure
Mumbai
O Unilever India Limit ed, Explosion St udy Of Un-Op varnish in t he mist form at
Mumbai elevat ed t emperat ure
O Ciba India Pvt . Ignit ion Temperat ure, DTA Open Cup And Gas Evolut ion
Limit ed, Mumbai Test For Irganox And 3-Met hyl 4-Nit rophenol
O Unilever India Explosion St udy Of Chlorinat ed Isocyanurat es
Limit ed, Mumbai at elevat ed t emperat ures
O IOCL-Ahmedabad Risk Analysis of Aut o-LPG filling syst em at IOCL,
Gokulesh Pet roleum, Narol, Ahmedabad
O IOCL-Ahmedabad Risk Analysis of Aut o-LPG dispensing syst em at IOCL
Guj arat Aut o Cent re, Usmanpura, Ahmedabad
O IOCL-Ahmedabad Risk Analysis of Aut o-LPG filling syst em at IOCL,
Rasht riya Aut o, Behrampur, Ahmedabad
O OO OO IOCL-Ahmedabad Risk Analysis of Aut o LPG filling syst em at IOCL,
Sarda Pet rol eum Chandkheda, Gandhi nagar
O OO OO Bayer (India) Limit ed Consequence Analysis of Vulkanox 4688
Thane, Mumbai Hydrogenat i on
O IOCL-Bangalore Risk Analysis and HAZOP st udies of LPG Bot t ling plant
O SRAACL, Kurnool Safet y Audit of Caust ic Soda and Fat t y Acid Division
of Sree Rayalaseema Alkalies & Allied Chemicals
Limit ed.
PARTY PROJECT
133
PARTY PROJECT
O Navin Fluorine Indust ries, Pilot Plant process on HFC-134a
Mumbai
O SRF Lt d, New Delhi Pilot Plant process on HFC-134a
O MNES, New Delhi Advanced Bi omass Gasi f i cat i on
O IFCPAR, New Delhi - Novel synt het ic met hodologies in combinat orial
(Indo French collaborat ion chemist ry for t he preparat ion of bioact ive
proj ect ) molecules libraries
O Dart Manufact uring (P) Lt d, Ident ificat ion of t he fungus at t acking t he product
Hyderabad and suggest ion of suit able remedial measures for
t he cont rol of t he fungus
O V Life Sciences Technologies Ant i -i nfl ammat ory pot ent i al of synt het i c
Pvt . Lt d., Pune compounds in rat paw edema model
O DST, New Delhi Design, Synt hesis & evaluat ion of Nonlinear
Opt ical Propert ies of Novel Organic & Met allic
Molecular Mat erials
O MSN Laborat ories Lt d, Sub-acut e Toxicit y st udy of Ezet imibe and
Hyderabad Resuvast at in calcium in Mice and Rat s
O DBT, New Delhi Product ion of Alkaline Prot eases by using
Immobi l i zed Baci l l us Li cheni f ormi s i n st i rred t ank
and zed bed React ors
O DST, New Delhi Signal Chemicals in Plant s during Nodulat ion
O DST, New Delhi Process and product st andardizat ion of classical
ayurvedic drugs wit h special reference t o
rheumat i sm
O DBT, New Delhi Designing novel liposomal gene delivery reagent s
& invest igat ing t he role of size & surface change
of lipid-DNA complex in liposomal gene delivery
Process Safet y Cent er has undert aken and submit t ed t he report on Risk Analysis and HAZOP
studies for following clients..
O Anabond Limit ed, Chennai Risk Analysis and HAZOP st udies of Proposed
PC
4
at Ezhichur Village, Sriperumbudur Taluk,
Chengalpat t u Dist , Tamilnadu
O Bayer (India) Limit ed, Hazard and Operabilit y st udies of NaMBT Plant
Thane, Mumbai
Technologies/ Processes/ Reports Released
134
PARTY PROJECT
O OO OO BPCL, Bangalore Risk Analysis of Aut o-LPG filling syst em at
Arunodaya filling st at ion, Gangadhara Nagar,
Bangal ore
O OO OO BPCL, Bangalore Risk Analysis of Aut o-LPG dispensing syst em at
Chanders fi l l i ng st at i on, Gandhi nagar, Bangal ore.
O BPCL, Bangalore Risk Analysis of Aut o-LPG dispensing syst em at
Sankara Servi ce st at i on, Mal l eswaram,Bangal ore.
O M/ s. I.T.C Limit ed, Paper Risk Analysis of LPG st orage facilit ies at Sarapaka,
Boards & Specialt y Papers Khammam Di st .
Division, Sec-bad.
O IOCL, Ahmedabad Risk Analysis of Aut o LPG dispensing st at ion at
M/ s. Vij ay Pet roleum Ret ail out let , Rakhial,
Ahmedabad
O The Andhra Sugars Limit ed, Risk Analysis of t he proposed UH-25 Plant at Tanuku
Tanuku
O BASF India Limit ed Mangalore A Report on Evaluat ion of Safet y Propert ies of t he
Dyes/ Col orant s.
O IOCL, Ahmedabad Risk Analysis of Aut o-LPG dispensing st at ion at
M/ s. Dhanalaxmi Pet roleum, Vij aynagar,
Ahmedabad.
O IOCL, Ahmedabad Risk analysis of Aut o-LPG dispensing st at ion at
M/ s. Omkar Pet roleum, Subhanpura, Vadodara.
O IOCL, Ahmedabad Risk analysis of Aut o-LPG dispensing st at ion at
M/ s. Shreenat hj i Aut o point , Amraiwadi,
Ahmedabad.
O BPCL, Cherlapally, Hyderabad. Ext ernal Safet y Audit of POL Depot Cherlapally
O CIBA India Pvt .Lt d, Mumbai. DTA, Gas evolut ion & BAM Oven t est Repor t
O HPCL, Visakhapat nam Quant it at ive Risk Analysis of t he field rooms
locat ed in different process unit s (PRU-DHDS &
FCCU-I(R)
O BPCL, Cherlapally, Hyderabad Damage cont ours and basis of LPG leakage in
LPG unloading Gant ry at Cherlapally
O ASL, Tanuku HAZOP st udies of t he proposed liquid Hydrogen
pl ant at Saggonda
135
O New a-gl ucosi dase i nhi bi t ors and t hei r synt hesi s
from a nat ural source by J M Rao, R Jagadeeshwar
Rao, U Sampat h Kumar, S Venkat Reddy, A K Tiwari ,
J S Yadav, V Raghavan Patent US (1/ 4/ 03) dat ed
10/ 403034
O A n o vel met h o d f o r ch r o mat o g r ap h i c f i n g er
pri nt i ng and st andardi zat i on of si ngl e medi ci nes
and formulat ions by D Vij aya Kumar, K V Raghavan
Yugoslavia Patent 255/ 2003 (3/ 4/ 03), Korea (2/ 6/
03), UAE (8/ 6/ 03) 178/ 2003
O A process f or t he preparat i on of b-ket o al i phat i c
acid est er useful as t herapeut ic agent by Annapurna
Jet t y, D M Akkewar, K V Raghavan. Pat ent [PT-327]
US (16/ 5/ 03) 10/ 439174 (Divisional)
O An i mp r oved p r ocess f or t h e p r et r eat men t of
veg et ab l e o i l s f o r p h ysi cal r ef i n i n g b y P P
Chakrabart i, B V S K Rao, S K Roy, BLA Prabhavat hi
Devi , K N Prasanna Rani , V Vandana, C Kal yani , K
Gaddam, Vij ay Kale, R B N Prasad Pat ent [PT-371]
PCT (30/ 5/ 03) PCT/ IN03/ 00203 US (30/ 5/ 03) 10/
449698
O A novel herbal composi t i on f or t he t reat ment of
cancer b y J M Rao, P V Sr i ni vas, J S Yad av, K V
Raghavan, A K Saxena, M Shanmugavel, H Kampasi,
G N Qazi. Pat ent [PT-351] US (17/ 6/ 03) 10/ 463060
(Divisional) India (6/ 11/ 03) 1837/ DELNP/ 03
O Imp r oved p r ocess f or t he synt hesi s of cal i x (4)
p yr r ol es over mol ecul ar si eve cat al yst s b y K V
Raghavan, S J Kulkarni, M Radha Kishan, N Srinivas.
Pat ent [PT-306] US (29/ 7/ 03) 10/ 609151 France
( 2 5 / 8 / 0 3 ) 1 9 1 5 6 5 1 . 2 US ( 2 9 / 7 / 0 3 ) / 6 0 9 1 5 1
France (25/ 8/ 03) 1915651.2
O Enzymat i c process f or prepari ng reduced-cal ori e
fat s cont aining behenic acid by T N B Kaimal, Sanj it
Kanj i l al , R B N Prasad, Gaf oorunni sa. Pat ent [PT-
192] US (28/ 8/ 03) (Divisional)
O A chemoenzymat i c process f or t he st erosel ect i ve
p r ep ar at i on of b ot h r and s enant i omer s of 3-
hydroxy-3-phenyl propanenit rile by Ahmed Kamal,
G B Ramesh Kh an n a, M Ven k at esw ar Rao, K V
Rag h avan . Pat ent [ PT- 3 0 0 ] GB ( 2 5 / 7 / 0 3 )
0317492.7 Japan (19/ 9/ 03) 2002-558527
O An improved process for t he enhancement of cycle-
l i f e of t he zi nc chromi um based cat al yst used i n
t he synt hesis of 2-met hylpyrazine by P S Saiprasad,
K V Raghavan, P Kant a Rao, S J Kulkarni, K Narasimha
Rao, R Gopinat h, S Farsinavis, H M Meshram. China
dat ed (27/ 9/ 03), Pat ent 01823096.2 Japan dat ed
(29/ 9/ 03), Pat ent 2002-577798, Korea dat ed (29/
9/ 03) Pat ent 2003-7012759, EP dat ed (29/ 9/ 03),
Pat ent 01934298.9
O An i mp r oved p r ocess f or t he synt hesi s of ar yl
pyridine base over zeolit e cat alyst s by S J Kulkarni,
K V Raghavan, V Radha Rani , N Sri ni vas EP dat ed
(29/ 9/ 03) Patent No. 1934301.1 Japan dated (29/
9/ 03) Pat ent 2002-577788
O Process for t he preparat ion of 2-met hyl 1,4- napt ho
q u i n o n e b y S Nar ayan an , KVVSBSR Mu r t h y, K
Madhusudan Reddy, N Premchandar Japan dat ed
(29/ 9/ 03) Pat ent 2002-577762 India dat ed (11/
9/ 03)
O An i mp r o ved p r o cess f o r t h e syn t h esi s o f
oct ahydro acri di ne (annul at ed pyri di nes) by S J
Kul karni , K V Raghavan, V Radha Rani , N Sri ni vas
Pat ent Japan (29/ 9/ 03) EP (29/ 9/ 03) 1934295.5
O An improved process for t he synt hesis of porphyrin
compounds over mol ecul ar si eve cat al yst s under
microwave irradiat ion by S J Kulkarni, K V Raghavan,
M Radha Kishan, N Srinivas. Japan (29/ 9/ 03) Pat ent
2002-577829 EP (29/ 9/ 03) Pat ent 1932048
O An improved process for t he synt hesis of aliphat ic
cyclic amines by S J Kulkarni, K V Raghavan, V Radha
Rani, N Srinivas Japan (29/ 9/ 03) 2002-577787 EP
(29/ 9/ 03) 1934304.5
O Novel her b al comp osi t i on f or t he t r eat ment of
gast r i c ul cer by J M Rao, A K Ti war i , U Sampat h
Kumar, B S Sast ry, J S Yadav, K V Raghavan, Gaut am
Pal i t , D N Bh al l a, Deep ak Rai , P M Var i er, T S
Mural eedharan, K Mural eedharan
O Pr o cess f o r si mu l t an eo u s p r ep ar at i o n o f
nanocryst al l i ne t i t ani um di oxi de and hydrazi ne
mo n o h yd r o ch l o r i d e b y S V Man o r ama, K
Madhusudana- Reddy, P Basak, C K Nisha, C V Gopal
Reddy US (13/ 11/ 03) 10/ 714290 PCT (20/ 11/ 03)
PCT/ IB03/ 05251 India (11/ 12/ 03) 1538/ DEL/ 03
PATENTS FILED IN INDIA AND OVERSEAS PATENTS FILED IN INDIA AND OVERSEAS PATENTS FILED IN INDIA AND OVERSEAS PATENTS FILED IN INDIA AND OVERSEAS PATENTS FILED IN INDIA AND OVERSEAS
2003-04. 2003-04. 2003-04. 2003-04. 2003-04.
136
O Pr o cess f o r t h e d evel o p men t o f i n exp en si ve,
al t er n at i ve, o xyg en b ar r i er mat er i al f o r t h e
packaging indust r y by K V S N Raj u, K I Suresh, B S
Si t aramam, S Sri dhar, Asad Al i Khan PCT (29/ 12/
03) PCT/ IN03/ 00407 US (30/ 12/ 03) 10/ 747616
India (27/ 2/ 04
O Novel (2-fluoropyrrolo [2,1-c] [1,4] benzodiazepine
di mmers usef ul as ant i cancer agent s by Ahmed
Kamal, P S Murali Mohan- Reddy, D Rajasekhar Reddy
US (31/ 12/ 03) PCT (31/ 12/ 03) PCT/ IN03/ 00448
O Ti r uchend ur ami ne and d er i vat i ves -car b ol i ne
d er i ved g u an i d i n e al kal o i d s as - g l u co si d ase
inhibit ors by Y Venkat eswarlu, K Ravinder, J S Yadav,
Y Sar at h Ku mar, S Ramak r i sh n a, P V Di w an , J
Venkat eswara Rao, P Ramesh, Har t mut Laat sch -
US (31/ 12/ 03) PCT (31/ 12/ 03) PCT/ IN03/ 00444
O Novel nonnat ural c-l i nked carbo-b-pept i des wi t h
robust secondar y st ruct ures by G V M Sharma, K
Ravi nder Reddy, P Radha Kri shna, A C Kunwar, A
Ravi Shankar, B Jagannadh, P Jayaprakash - India
(31/ 3/ 04) 641/ DEL/ 04
O New a-glucosidase inhibit ors from a nat ural source
by J M Rao, P V Sri ni vas, V Anuradha, A K Ti war i ,
Amt ul Zehra Al i , J S Yadav, K V Raghavan - India
(27/ 2/ 04)
O C8-l i nked p yrrol [ 2,1-C] [ 1,4] b enzodi a zep i ne -
Acridone Acridine Hybrids as Ant i-Tumour Agent s
by Ahmed Kamal, O Srinivas, P Ramulu, G Ramesh,
P Praveen Kumar - US (31/ 12/ 03) PCT (31/ 12/ 03)
PCT/ I N03/ 00464
O Subst it ut ed benzimidazoles linked t o pyrrolo [2,1-
c] [1,4] benzodi azepi nes as ant i cancer agent s by
Ahmed Kamal , P Ramul u, O Sri ni vas - US (31/ 12/
03) PCT (31/ 12/ 03) PCT/ IN03/ 00462
O A p r o cess f o r t h e p r ep ar at i o n o f su b st i t u t ed
d i h yr o p yr i d i n o n es u si n g p o l yan i l i n e sal t s as
cat alyst s by S Palaniappan, V J Rao, B Gangadasu -
US (31/ 12/ 03) PCT (31/ 12/ 03) PCT/ IN03/ 00455 -
India (20/ 2/ 04)
O Ph ar maceu t i cal co mp o si t i o n co mp r i si n g (- )-
seco i so l ar i ci r esi n o l b y J M Rao, A K Ti w ar i , U
Sampat h Kumar, J S Yadav, K V Raghavan - China
(20/ 1/ 04) Canada (22/ 1/ 04) Korea (26/ 1/ 04)
2004-7001130
O (+)-cycloolivil as ant ioxidant obt ained from nat ural source
namely st ereospermum personat um by J M Rao, A K Tiwari,
U Sampat h Kumar, J S Yadav, K V Raghavan - China (20/ 1/
04) 1823501.8 Canada (23/ 1/ 04)
O (-)-ol i vi l as ant i oxi dant whi ch i s obt ai ned f rom a
n ew n at u r al so u r ce n amel y st er eo sp er mu m
personat um by J M Rao, A K Ti war i , U Sampat h
Kumar, J S Yadav, K V Raghavan - China (20/ 1/ 04)
Japan (26/ 1/ 04) 2003-516509 Korea (27/ 1/ 04)
2004-7001212.
O Recovery of sodi um t hi ocyanat e f rom i ndust ri al
p r o cess so l u t i o n b y memb r an e b ased
nanofilt rat ion t echnique by S Sridhar, G S Murt hy,
D Suhanya, B Smit ha, M Ramakrishna - US (29/ 3/ 04)
O A process f or t he i nsi t u synt hesi s of support ed
ammoni um sal t s of het er op ol yaci ds b y P S Sai
Pr asad , K V Rag h avan , I Su r yan ar ayan a, K
Narasi mha Rao, Ch. Sri l akshmi , M Sant osh Kumar,
K Bhupal Reddy - Korea (31/ 3/ 04) Japan (31/ 3/
04) Korea (31/ 3/ 04) Japan (31/ 3/ 04) EP (31/ 3/ 04)
EP (31/ 3/ 04)
O Syn t h esi s of ch i r al f ur an ami n oaci d s as n ovel
p ep t i d e b ui l d i ng b l ocks b y T K Chak r ab or t y S
Tapadar - US (31/ 3/ 04)
O New p yr i mi d i n e l i n ked p yr r o l o (2,1- c) (1,4)
benzodi azepi nes as pot ent i al ant i t umour agent s
by Ahmed Kamal, K Laxma Reddy - India (29/ 5/ 03)
747/ DEL/ 03
O Part it ioned bat ch react or for improved product ion
o f al co h o l u si n g i mmo b i l i zed yeast b y R S
Prakasham, P N Sarma, J Joseph, M Ramakrishna,
Vedant achar y, K V Raghavan - India (17/ 6/ 03) 810/
DEL/ 03
137
O Novel cat ionic amphiphiles for int racellular delivery
of t herapeut ic molecules molecules it s composit ion,
p r o cess an d u se t h er eo f b y M Bh ar at Ku mar,
Arabi nda Chaudhuri , Y Ramdas, N Madhusudana
Rao - India (11/ 9/ 2003)
O Novel vit amin b12 - biodegradable micro part iculat e
conj ugat e carri er syst ems f or peroral del i very of
i nj ect abl e drugs, t herapeut i c pept i des/ prot ei ns
and vaccines by Kishore B Chalasani, P V Diwan, K V
Raghavan, G J Russell Jones, S K Jain, K Kot eshwar
Rao - India (25/ 8/ 03)
O A p r o cess f o r i n - si t u d ep o si t i o n o f si l ver o n
act ivat ed carbon by K S Rama Rao B David Raj u, P
Venkat eswar Rao, V Siva Kumar, A H Padmasri, K V
Raghavan - India (28/ 8/ 03)1055/ DEL/ 03
O Al kyl xant hat es and t hei r use as a pest i ci des by J
Venkat eswara Rao, Y Venkat eswarlu, K V Raghavan
- India (24/ 9/ 03) 1530/ DELNP/ 03
O An i mp r oved p r ocess f or t he p r ep ar at i on of n-
p h o sp h o n o met h yl g l yci n e b y D S Iyen g ar
P Neelakant an, B Vit t al Rao, D Subhash Reddy, Sri
Kumar an Thamby, R Rangar aj an, D K Kohi l , B S
Makwana - India (30/ 9/ 03) 1223/ DEL/ 03
O A p r ocess f or p r ep ar at i on of b i oact i ve cat i oni c
amp h i p h i l es. b y M Bh ar at Ku mar Ar ab i n d a
Chaudhuri, Y Ramdas, N Madhusudana Rao - India
(6/ 11/ 03) 1836/ DELNP/ 03
O A novel met hod of st andardizat ion of chemical and
t herapeut i c val ues of f oods and medi ci nes and
pat hol ogi cal propert i es/ condi t i ons i n bi ol ogi cal
sampl es by chromat ographi c f i ngerpri nt i ng by D
Vij ayakumar, K V Raghavan - India (28/ 1/ 04) 137/
DEL/ 04
O A process f or t he i n si t u synt hesi s of support ed
ammoni um sal t s of het er op ol yaci d s b y P S Sai
Pr asad, K V Rag h avan , I Su r yan ar ayan a, K
Narasimha Rao, Ch. Srilakshmi, M Sant osh Kumar, K
Bhupal Reddy (China)
O A novel herbal composi t i on f or t he t reat ment of
cancer by J Madhusudana Rao, P V Srinivas, J S Yadav,
K V Rag havan, A K Saxena, M Shanmug avel , H
Kampasi, G N Qazi (Canada, Korea, Japan).
O A novel C6-subst it ut ed furanoid sugar amino acids
and improved process for preparing t he same by T
K Chakrabor t y, G Sudhakar (India, US, PCT)
O Process for preparing nanosized, t hermally st able,
and hi gh sur f ace ar ea mul t i -comp onent met al
oxi des by B Mahi pal Redd y, At aul l ah Khan, P M
Sreekant h, P Lakshmanan (India, US)
O Pyrrol o [2,1-c][1,4] benzodi azepi ne-napt hal i mi de
conj ugat es linked t hrough piperazine moiet y and
process for preparat ion t hereof by Ahmed Kamal,
R Ramu, G B Ramesh Khanna (India, PCT, US)
O Syn t h esi s of ch i r al f u r an ami n oaci d s as n ovel
p ep t i d e b u i l d i n g b l o cks b y T K Ch ak r ab or t y,
Subhasish Tapadar (India, PCT)
O Recovery of sodi um t hi ocyanat e f rom i ndust ri al
p r o cess so l u t i o n b y memb r an e b ased
n an o f i l t r at i o n t ech n i q u e b y S Sr i d h ar, G
Sur yanar ayana Mur t hy, D Suhanya, B Smi t ha, M
Ramakri shna (PCT).
O Pr o cess f o r p r ep ar i n g (s)- al p h a- cyan o - 3-
phenoxybenzyl -(s)-2-(4-chl orophenyl )-i soval erat e
by V V Narayana Reddy, K Ishrat ullah, PV K Raj u, T
Ramesh Babu, M Mahesh, C Venkat eswara Reddy
2004-05 2004-05 2004-05 2004-05 2004-05
Patents Filed in India and Overseas during
138
O An enant ioconvergent chemoenzymat ic synt hesis
of ( R)--amino-b- acid ((R)- GABOB) by Ahed Kamal,
G B Ramesh Khanna, T Krishnaj i, R Ramu (US)
O A cat al yt i c p r o cess f o r si mu l t an eo u s f u r f u r al
hydrogenat i on-cycl ohexanol dehydrogenat i on i n
vap or p hase b y K S Rama Rao, B Davi d Raj u, S
Nar ayan an , B M Nag ar aj a, A H Pad masr i , V
Sivakumar, V Shashikala, P Seet haramulu, S S Reddy
(India, US)
O Immobilized FR(III) over HY zeolit e: An ecofriendly
p hot o-f en t on cat al yst b y M Sub r ahmanyam, V
Durga Kumari , M Noorj ahan (India, US, PCT)
O An improved liquid phase process for t he synt hesis
of oct ahydroacridine and oct ahydrphenant hridine
(annulat ed pyridines) over molecular sieve cat alyst .
by S J Kulkarni, KVV Krishna Mohan, N Narender, K V
Raghavan (India, PCT, US)
O An improved met hod for adsorpt ion and reduct ion
of hexaval ent chr omi um. by G Par t hasar at hy, B
Sreedhar, B M Choudary (US)
O A n ovel 1-(ar yl oxy) p r op i on oyl -2-ar yl sul f on yl
hydrazi nes usef ul as hyp ogl ycemi c agent s by T
Ramal i ngam, Y V D Nageswar, S Ramakri shna, A
Bhaskar Rao, P V Di wan, S Yadav, K V Raghavan
(India)
O New 4b - 1" - [ 2" - (su b st i t u t ed b en zo yl an i l i n o ]
podophyl l ot oxi n anal ogues usef ul as ant i -cancer
agent s b y Ahmed Kamal , P S M Mohan Red d y
(India)
O A process for racemi sat i on of undesi red opt i cal l y
act i ve i somer (R) 2(4- Chl orop hynyl )-3-met hyl
but anoic acid (R ) CPMBA by V V Narayana Reddy,
K Ishrat ullah, P V K Raj u, T Ramesh Babu, M Mahesh,
C Venkat eswara Rao (India)
O Process for t he preparat ion of polyuret hane polyol
f rom cardanol and ri gi d f oams t heref rom by K I
Suresh, V S Kishan Prasad (India, PCT, US)
O A novel met hod for t he evaluat ion of porphyrins,
calix(4) pyrroles and allied macrocyles over zeolit e
backed t lc plat es using high performance t hin layer
ch r o mat o g r ap h y(h p t l c) u n d er mi cr o w ave
irradicat ion by P Sit a Devi, K V Raghavan, S J Kulkarni,
M Radha Kishan, V Radha Rani, MRVS Murt hy (EP)
O New p yr r o l o [ 2,1- c] [ 1,4] b en zo d i azep i n e-
ant hraqui none conj ugat es usef ul as ant i t umour
agent s b y Ahmed Kamal , R Ramu, G B Ramesh
Khanna (India, US, PTC)
O New herbal composit ion for t reat ing gast ric ulcer
by J Madhusudana Rao, U Kumar B S Sast r y, J S
Yadav, K V Raghavan, Gaut am Palit , Madhu Dikshit ,
Deep ak Rai , P M Var i er, T S Mu r al eed h ar an , K
Muraleedharan (India, China, Canada, EP, JP)
O An i mp r oved p r ocess f or t h e p r et r eat men t of
veg et ab l e o i l s f o r p h ysi cal r ef i n i n g b y P P
Chakrabar t i , BVSK Rao, S K Roy, BLA Prabhavat hi
Devi , K N Prasanna Rani , V Vandana C Kal yani , K
Gaddam, Vij ay Kale, R B N Prasad (Indonesia)
O An improved process for t he preparat ion of et hyl
2,3-dihydrobenzo [1,4] dioxin -2- carboxylat e by M
Pardhasaradhi, G Kumaraswamy, A K Das, Nivedit a
Jena, C J Snehalat ha Nair (China, GB, Korea, Poland)
O Nat urally occurring coumarins and t heir precursors as
acet ycholineest erase inhibit ors by J Madhusudana Rao, B
Chinaraju, P V Srinivas, K S Babu, J S Yadav, K V Raghavan, H
K Singh Chandiswar Nat h (US)
O An i mproved process f or t he synt hesi s of novel
cat i oni c amphi phi l es f or i nt racel l ul ar del i very of
t h er ap eu t i c mo l ecu l es b y M Bh ar at Ku mar,
Arabinda Chaudhuri, Y Ramadas, N M Rao (JP)
139
O New pyrrolo [2,1-C] [1,4] benzodiazepines useful as
ant it umour agent s by Ahmed Kamal, P S M Mohan
Reddy (India)
O New n o n - cr o ss- l i n ki n g p yr r o l l o [ 2,1- C] [ 1,4]
benzodi azepi nes usef ul as pot ent i al ant i -cancer
agent s by Ahmed Kamal, G Ramesh, O Srinivas, P
Ramulu (India)
O New a-gl ucosi dase i nhi bi t ors and t hei r synt hesi s
f rom a nat ural source by J Madhusudana Rao, R
Jagadeeshwar Rao, U Sampat h Kumar, S Venkat
Reddy, A K Tiwari , J S Yadav, K V Raghavan (India)
O Inclusion complex of ant i-t ubercular rifampicin wit h
b et a- cycl o d ext r i n o r 2- h yd r o xyp r o p yl b et a-
cyclodext rin and a process for producing t he same.
b y K Rama Rao N Bh an u mat h i , J S Yad av, N S
Krishnaveni (India)
O Sequent i al b at ch react or wi t h t echnol ogy wi t h
b i o f i l m co n f i g u r at i o n f o r t r eat men t co mp l ex
chemi cal and p har maceut i cal ef f l uent s b y SVR
Venkat a Mohan, P N Sarma, N Chandrasekhara Rao,
K Krishna Prasad, K V Raghavan (India)
O A p r o cess f o r t h e p r ep ar at i o n o f 1,1,1,2-t et r a
f l uoroet hane f rom 1,1-di chl oro t et raf l uoroet hane
by S Narayan Reddy, P Shant an Rao, G Anuradha, B
Narsaiah Y Rambabu, PVSS Srinivas, K Ravindranat h
(India)
O An i mp r o ved p r o cess f o r 2,2- d i ch l o r o - 1,1,1-
t ri f l uoroet hane (HCFC-123) by P Shant an Rao, Y
Ramb ab u , S Nar ayan Red d y, M Sr i d h ar, PVSS
Srinivas,T Yakaiah, BPV Ligaiah (India)
O An improved process for t he preparat ion of 2,2,2-
t ri f l uoroet hanol by B Narsai ah P Shant an Rao, S
Narayan Reddy, PVSS Srinivas (India)
O Ti r uchendur ami ne and der i vat i ved b -car b ol i ne
d er i ved g u an i d i n e al kal o i d s as a- g l u co si d ase
i nhi b i t or s b y Y Venkat eshwar l u, K Ravi nder, J S
Yadav, Y Sarat h Kumar S Ramakrishna, P V Diwan, J
V Rao, P Ramesh, Hart mut Laat sch (India)
O C2- f l u o r o p yr r o l o [ 2,1- C] [ 1,4] b en zo d i azep i n e
dimers by Ahmed Kamal P S Murali Mohan Reddy,
D Raj asekhar Reddy (India)
O C8-l i n ked p yr r ol o[ 2,1-C] [ 1,4] b en zod i azep i n e-
acridone/ acridine hybrids by Ahmed
Kamal, O Srinivas, P Ramulu, G Ramesh Khanna, P
Praveen Kumar (India)
O A process f or t he preparat i on of hi ghl y ef f i ci ent
si l ver d ep o si t ed o n car b o n co ver ed al u mi n a
cat alyst in cont rolling microorganism in wat er by
K S Rama Rao, B Davi d Raj u , A H Pad masr i , V
Si vakumar, A Naga Rat nakar, P Seet haramul u, V
Shashikala, B M Nagaraj a, S Sreevardhan Reddy, P
N Sar ma, K Kr i shna Prasad, S R Venkat a Mohan
(India)
O Th er ap eu t i c ed i b l e co mp o si t i o n f o r t r eat i n g
hyperglycemia by A S Chauhan, Ch Kishore Babu, S
Sridevi, Y Sharat h Kumar, K Raj asekhar, G M Char y
(India)
Patents Filed in India and Overseas during
140
O An i mp r o ved p r o cess f o r t h e p r ep ar at i o n o f
pyri di ne and pyri di ne deri vat i ves f rom et hanol .
Pat ent No: 188716 Dt : 14/ 8/ 03
O A p r o cess f o r t h e p r ep ar at i o n o f 5-o xy 1-1,3-
dioxepanes. Pat ent No: 188717 Dt : 14/ 08/ 03
O A process for preparat ion of novel N-hydroxy alkyl
co n t ai n i n g cat i o n i c amp h i p h i l es. Pat ent No:
189751 Dt : 27/ 01/ 04
O A p r o cess f o r t h e p r ep ar at i o n o f n o val
di pyranoqui no-l i nones usef ul as ant i -HIV agent s.
Pat ent No: 190036 Dt : 03/ 02/ 04
O An i mp roved p rocess f or t he p rep arat i on of N-
met hylpiperazine. Patent No: 189382 Dt: 03/ 02/ 04
O An i mp r o ved p r o cess f o r t h e si mu l t an eo u s
preparat ion of pyridine and picolines. Pat ent No:
189373 (24/ 02/ 04
cyanopyridines. Pat ent No: 190432 Dt : 24/ 02/ 04
O A p r o cess f o r t h e p r ep ar at i o n o f cr yst al l i n e,
van ad i u m si l i co - al u mi n o p h o sp h at e cat al yst s
usef ul f or aci d cat al ysed r eact i ons. Pat ent No:
190239 Dt : 12/ 03/ 04
acet onit rile. Pat ent No: 190763 Dt : 15/ 3/ 04
benzonit rile. Pat ent No: 190760 Dt : 15/ 03/ 04
car b amat es usef ul f or ag r och emi cal s, p h ar ma
ceut icals and pept ide synt hesis. Pat ent No: 190827
Dt : 16/ 03/ 04
2004-05 2004-05 2004-05 2004-05 2004-05
acet onit rile from et hanol over vanadium alumino
phospat e cat alyst . Patent No: 191169 Dt: 12/04/04
acet onit rile. Pat ent No: 191083 Dt : 12/ 4/ 04
amides. Pat ent No: 191100 Dt : 12/ 4/ 04
O A new process for t he preparat ion of aromat ic nit ro
compounds. Pat ent No: 191095 Dt : 12/ 4/ 04
O An improved process of preparat ion of propanola
mines as t herapeut ic agent s. Pat ent No: 191210
Dt : 26/ 04/ 04
O An i mp r o ved p r o cess f o r t h e en zymat i c
p r ep ar at i on of op t i cal l y p ur e g l yci d at e est er s.
Pat ent No: 191208 Dt : 26/ 04/ 04
O A process f or t he preparat i on of novel hydroxy
al kyl cont ai ni ng cat i oni c amphi phi l es usef ul f or
i n t r acel l u l ar d el i ver y o f b i o l o g i cal l y act i ve
molecules. Pat ent No: 191266 Dt : 26/ 04/ 04
O A p r ocess f or t he p r ep ar at i on of ant i mi cr ob i al
f ract i on f rom mi l l i ngt oni a hort ensi s. Pat ent No:
191243 Dt : 26/ 4/ 04
O An i mproved process f or t he preparat i on of 4,4
diaminobenzanilide (DABA). Patent No: 191481 Dt:
30/ 06/ 04
O A process f or t he synt hesi s of new het erocycl i c
sub st i t ut ed sul f ami d es usef ul as an t i b act er i al
agent s. Pat ent No: 191416 Dt : 24/ 05/ 04
O An i mproved process f or acyl at i on of napht hyl
et hers. Pat ent No: 191514 Dt : 30/ 06/ 04
O An improved process for preparat ion of ferrocene
capped olefins. Pat ent No: 191497 Dt : 30/ 06/ 04
O An i mproved process f or t he preparat i on of 4b-
su b st i t u t ed ep i p o d o p yl l o t o xi n s. Pat ent No:
191366 Dt : 16/ 11/ 04
O A process for t he preparat ion of novel N-hydroxy
al kyl cont ai ni ng cat i oni c amphi phi l es usef ul f or
i n t r acel l u l ar d el i ver y o f b i o l o g i cal l y act i ve
molecules. Pat ent No: 192393 Dt : 08/ 02/ 05
PATENTS GRANTED IN INDIA PATENTS GRANTED IN INDIA PATENTS GRANTED IN INDIA PATENTS GRANTED IN INDIA PATENTS GRANTED IN INDIA
2003-04 2003-04 2003-04 2003-04 2003-04
141
O Process for synt hesis of novel cat ionic amphiphiles
cont ai ni ng N-hydroxyal kyl group f or i nt racel l ul ar
delivery of biologically act ive molecules. Pat ent No:
US 6541649 Dt : 1/ 4/ 03
O Process for t he preparat ion of support ed osmat es.
Pat ent No: US 6559291 Dt : 06/ 05/ 03
O Process f or t he preparat i on of et hyl 2,3-di hydro
b en zo [ 1,4] d i o xi n - 2- car b o xyl at e. Pat ent No:
6555695 Dt : 29/ 04/ 03
O Pr ocess f or t h e p r ep ar at i on of d i azon ap h t h o
quinone sulfonyl-chlorides using diphosgene and
t riphosgene. Patent No: US 6559291 Dt: 06/ 05/ 03
O (+) cycloolivil as ant ioxidant obt ained from nat ural
so u r ce n amel y st er eo sp er mu m p er so n at u m.
Pat ent No: US 6562381 Dt : 13/ 05/ 03
O Process for t he enhancement of t he cycle life of a zinc-
ch r o mi u m b ased cat al yst i n t h e syn t h esi s o f 2-
met hylpyrazine. Patent No: US 6566292 Dt: 20/ 05/ 03
O Process f or preparat i on of 2-Met hyl -1, 4-napht ho
quinone. Pat ent No: US 6579994 Dt : 17/ 06/ 03
O Al kyl xant hat es and use of al kyl xant hat es i n t he
i nt egr at ed p est man ag emen t . Pat ent No: US
6583175 Dt : 24/ 06/ 03
O Process f or t he preparat i on of a pol yani l i ne sal t .
Pat ent No: US 6586565 Dt : 01/ 07/ 03
O (-)-Ol i vi l as ant i oxi dant whi ch i s obt ai ned f rom a
n ew n at u r al so u r ce n amel y st er eo sp er mu m
personat um. Patent No: US 6592911 Dt: 15/ 07/ 03
O Subst i t ut ed cal yx (4 pyrrol es and process f or t he
synt hesis of calyx (4 pyrroles over molecular sieve
cat alyst s. Pat ent No: US 6605194 Dt : 12/ 08/ 03
O Process for t he preparat ion of N-(2,3-Dihydrobenzo
[1,4] dioxin-2-carbonyl) piperazine. Pat ent No: US
6608200 Dt : 19/ 08/ 03
O Preparat i on of al kyl at ed aromat i c ami nes. Pat ent
No: EP 1002789 Dt : 18/ 06/ 03
O Process for t he preparat ion of amine oxides. Pat ent
No: US 6617454 Dt : 09/ 09/ 03
O Enzymat i c process f or prepari ng reduced-cal ori e
fat s cont aining behenic acid. Pat ent No: US 6617141
Dt : 09/ 09/ 03
O Process for t he preparat ion of nit rot oluenes. Pat ent
No: US 6620981 Dt : 16/ 09/ 03
O Process for t he synt hesis of highly act ive modified
carbon support ed pal l adi um cat al yst . Pat ent No:
US 6624109 Dt : 23/ 09/ 03
O Pr ocess f or t he p r ep ar at i on of p ol yani l i ne sal t .
Pat ent No: US 6630567 Dt : 07/ 10/ 03
O Process for simult aneous alkyl est erificat ion of oil
and regenerat ion of spent oil purificat ion medium.
Pat ent No: US 6635595 Dt : 21/ 10/ 03
O Process for t he preparat ion of hydroxylat ed lecit hin
f r om cr u d e soyab ean l eci t h i n . Pat ent No: US
6638544 Dt : 28/ 10/ 03
O Support ed osmat es, process for preparat ion t here
of, and a process for t he preparat ion of chiral vicinal
diols using support ed osmat e cat alyst . Pat ent No:
US 6646168 Dt : 11/ 11/ 03
O Herbal chemical composit ion for t he t reat ment of
cancer. Pat ent No: US 6649650 Dt : 18/ 11/ 03
PATENTS GRANTED OVERSEAS PATENTS GRANTED OVERSEAS PATENTS GRANTED OVERSEAS PATENTS GRANTED OVERSEAS PATENTS GRANTED OVERSEAS
2003-04 2003-04 2003-04 2003-04 2003-04
142
O Met hod of processi ng of hydrogen f or reduct i ve
acylat ion of nit ro, azido and cyano arenas. Pat ent
No: US 6649650 Dt : 06/ 01/ 04
O Pyr i mi di ne l i nked p yr r ol o [ 2,1-C] [ 1,4] b enzodi a
zepines as pot ent ial ant it umour agent s. Pat ent No:
US 6683073 Dt : 27/ 01/ 04
O An i mproved process f or t he preparat i on of t he acyl
napt hyl et hers. Patent No: US 1149819 Dt: 16/ 04/ 03
O A process for t he preparat ion of acyl het ro aromat ic
compounds f rom het roaromat i c compounds by
met al ion exchanged clays. Pat ent No: EP 1138681
Dt : 15/ 10/ 03
O Process f or t he ni t rat i on of xyl ene i somers usi ng
zeolit es cat alyst . Pat ent No: US 6703532 Dt : 09/
03/ 04
O Process for t he preparat ion of support ed osmat es.
Pat ent No: US 6703531 Dt : 09/ 03/ 04
O Process for t he preparat ion of rice bran oil low in
phosphorous cont ent . Pat ent No: US 6706299
Dt : 16/ 03/ 04
O Process for preparing t axol side chain using het ero
g eneous t r i f unct i onal cat al yst . Pat ent No: US
6706901 Dt : 16/ 03/ 04
O Process f or t he separat i on of racemi c mi xt ures.
Pat ent No: US 6709597 Dt : 23/ 03/ 04
O Met h o d f o r t h e syn t h esi s an d eval u at i o n o f
porphyrins, calix (4 pyrroles and allied macrocycles.
Pat ent No: US 6712972 Dt : 30/ 03/ 04
2004-05 2004-05 2004-05 2004-05 2004-05
O Pr ocess f or p r ep ar i n g su b st i t u t ed cou mar i n s.
Pat ent No: US 6716996 Dt : 06/ 04/ 04
O Pr o cess f o r t h e p r ep ar at i o n o f 2- ch l o r o - 5-
met hyl pyri di ne-3-carbal dehyde. Pat ent No: US
6737529 Dt : 18/ 05/ 04
O 1-(aryl oxy) propi onoyl -2-aryl sul f onyl hydrazi nes,
process f or preparat i on t hereof and use t hereof
as hypoglycemic agent s. Pat ent No: US 6730704
Dt : 04/ 05/ 04
O Process for t he preparat i on of vi nyl pyri di ne from
p i col i ne over modi f i ed zeol i t es Pat ent No: US
6727365 Dt : 27/ 04/ 04
O Sel ect i ve l i qui d p hase ai r oxi dat i on of t ol uene
cat al ysed by composi t e cat al yt i c syst em. Pat ent
No: US 6743952 Dt : 01/ 06/ 04
O Process for t he t ransest erficat ion of ket o est er wit h
alcohol using polyaniline salt s as cat alyst s. Pat ent
No: US 6743942 Dt : 01/ 06/ 04
O Process for t he preparat ion of amine oxides. Pat ent
No: EP 6743952 Dt : 28/ 04/ 04
O Process for t he product ion of nit roarenes wit h high
para sel ect i vi t y f rom monosubst i t ut ed aromat i c
hydrocarbons usi ng al umi nosi l i cat es as cat al yst s.
Pat ent No: EP 1004570 Dt : 06/ 05/ 04
O A process for t he preparat ion of 4 -isobut y lacet o
p henone b y f r i edel cr af t s acyl at i on of i sob ut yl
benzene. Pat ent No: EP 1138662 Dt : 30/ 06/ 04
O Process for synt hesis of bis-(subst it ut ed-4-quinolyl)
disulphides. Pat ent No: US 6777553 Dt : 17/ 0804
O Mul t i funct i onal cat al yst useful i n t he synt hesi s of
chiral vicinal diols and process for t he preparat ion
of chi ral vi ci nal di ol s usi ng sai d mul t i f unct i onal
cat alyst s. Pat ent No: US 6780810 Dt : 24/ 08/ 04
143
O Process f or t he preparat i on of 2-ni t rot hi ophene
select ively from t hiophene using met al exchanged
clay cat alyst . Patent No: US 6794521 Dt: 21/ 09/ 04
O Pr ocess f or t he p r ep ar at i on of ZSM-5 cat al yst .
Pat ent No: US 6800272 Dt : 05/ 1004
O Pyrene-linked pyrrolo [2,1-c] [1,4] benzodiazepine
hybri ds usef ul as ant i -cancer agent s. Pat ent No:
US 6800622 Dt : 05/ 10/ 04
O Su p p o r t ed o smat es, p r o cess f o r p r ep ar at i o n
t hereof, and a process for t he preparat ion of chiral
vi ci nal d i ol s usi ng sup p or t ed osmat e cat al yst .
Pat ent No: US 6815566 Dt : 09/ 11/ 04
O Pr ocess f or t he p r ep ar at i on of nanocr yst al l i ne
zeolit e bet a. Pat ent No: US 6827924 Dt : 07/ 12/ 04
O Pr ocess f or t he p r ep ar at i on of nanocr yst al l i ne
zeolit e bet a. Pat ent No: US 6827924 Dt : 07/ 12/ 04
O Process for t he preparat ion of b-ket o aliphat ic acid
est er. Pat ent No: US 6838083 Dt : 04/ 01/ 05
O Process for t he preparat ion of (-)-epicat echin from
a new nat ural source namely dichrost achys cinerea.
Pat ent No: US 6841687 Dt : 11/ 01/ 05
O Composit ion for t reat ing gast ric ulcer and a process
f or prepari ng t he same. Pat ent No: US 6855347
Dt : 15/ 02/ 05
O Process for t he direct preparat ion of 5-alkoxy and
5- acyl o xy an al o g u es o f camp t o t h eci n s o r
mappicene ket ones. Pat ent No: US 6872829 (Dt :
29/ 03/ 05
O Pr ep ar at i on of new l ayer ed doub l e hydr oxi des
exch an g ed w i t h o smat e f o r asymmet r i c
dihyfroxylat ion of olefins t o vicinoldiols Pat ent No:
EP 1209142 Dt : 26/ 03/ 05
acylaromat ic et hers Pat ent No: JP 532824 Dt : 31/
05/ 04 EP 1149818 Dt : 29/ 12/ 04
O An i mp r oved p r ocess f or t h e p r ep ar at i on of t et r a
bromobisphenol-A. Patent No: JP 3532825 Dt: 31/ 5/ 04
O A novel chromat ographic finger print ing of herbal
medicines and formulat ions. Pat ent No: EA 004663
(24/ 6/ 04
O Process for t he preparat ion of acylferrocenes. Pat ent No:
JP 3574805 Dt : 9/ 7/ 04 Patent No: EP 1268501 Dt: 21/ 7/ 04
Patent No: CN 116674C (15/ 9/ 04
O Process for t he preparat ion of Malononit rile. Pat ent
No: EP 1184369 (11/ 8/ 04
O A process for t he preparat ion of 1,1,12-t et ra fluoroe
t hane. Pat ent No: GB 2375974 Dt : 11/ 8/ 04
O A new ant ioxidant from nat ural source. Pat ent No:
US 6781002 Dt : 24/ 8/ 04
O Pr ocess f or t he p r ep ar at i on of p ol yani l i ne sal t .
Pat ent No: AU 002242943 Dt : 26/ 8/ 04
O An ecof r i en d l y p r ocess f or t h e p r ep ar at i on of
dinit ramidic acid and salt s by met al ion exchanged
clay cat alyst s. Pat ent No: US 6787119 Dt : 7/ 9/ 04
Pat ent No: EP 1344748 Dt : 15/ 12/ 04
O A process for t he alkylat ion of dihydroxy benzene
wi t h t ert i ary but yl al cohol usi ng sol i d aci d and
p o l yan i l i n e su l f i d e cat al yst s. Pat ent No: GB
2378441 Dt : 22/ 9/ 04 Pat ent No: FR 2822822 Dt :
24/ 9/ 04
O Process for t he preparat ion of amine oxides Pat ent
No: EP 1213280 Dt : 29/ 9/ 04
O Al kyl xant hat es and use of al kyl xant hat es i n t he
i nt egr at ed p est man ag emen t . Pat ent No: EP
1373238 Dt : 3/ 11/ 04
O St ereoselect ive preparat ion of 3-hydroxy-3-phenyl
propionit rile. Pat ent No: GB 2387597 Dt : 10/ 11/
04
O Vi t ami n B12-b i o d eg r ad ab l e mi cr o p ar t i cu l at e
conj ugat e carri er syst ems f or peroral del i very of
drugs, t herapeut ic pept ides / prot eins and vaccines.
Pat ent No: GB 2374010 Dt : 29/ 12/ 04
Patents Granted Overseas During
144
ARAVINDAN, PG;SELVANAYAGAM, S;YOGAVEL, M; VEL
MURUGAN, D; RAVIKUMAR, K;NAGARAJAN, N;PERUMAL,
PT, 3-ch l o r o -3-(9-et hyl -6-met hyl -9H-car b azo l -3-yl )
propenal Act a Cryst al l o graphi ca
Sect ion E(St ruct ure Report s Online) (2003) 59(9) :
O1432-O1434
ARAVINDAN, PG;SELVANAYAGAM, S;VELMURUGAN,
D;RAVIKUMAR, K; NAGARAJAN, R;PERUMAL, PT, C-
Hal ogen cent er dot cent er dot cent er dot pi i nt eract i
ons in 4-chloro-2-(9-et hylcarbazol-3-yl)quinoline-1(2H)-
carbal dehyde
Act a Cryst allo graphica, Sect ion E (St ruct ure Report s
Online) (2003) 59(10):O1564-O1566
BABU, KS;SRINIVAS, PV;PRAVEEN, B;KISHORE, KH;MURTY,
US;RAO, JM, An t i mi cr o b i al co n st i t u en t s f r o m t h e
rhizomes of Rheum emodi
Phyt ochemist ry (2003) 62(2) : 203-207
BABU, KS;RAJU, BC;PRAVEEN, B;KISHORE, KH;MURTY,
US;RAO, JM, Mi cr o w ave assi st ed syn t h esi s an d
ant imicrobial act ivit y of 2,2-dimet hylchromenes
Het erocyclic Communicat ions (2003) (9) : 519-526
BABU, KS;RAJU, BC;SRINIVAS, PV;RAO, JM, Highly efficient
and chemosel ect i ve cl eavage of prenyl et hers usi ng
ZrCl
4
/ NaBH
4
Tet rahedron Let t ers (2003) 44(12) : 2525-2528
BABU, KS;RAJU, BC;SRINIVAS, PV;SRIDHAR, A;KUMAR, SP;
RAO, JM, A simple, efficient and highly select ive cleavage
o f 3- met h yl b u t - 2- en yl (p r en yl )et h er s u si n g p -
t oluenesulfonic acid
Chemist ry Let t ers (2003) 32(8) : 704-705
BANERJEE, RAJKUMAR; KUMAR DAS, PRASANTA;
SRILAKSHMI, GOLLAPUDI VENKATA; RAO, NM;
CHAUDHURI, A, Novel Cat i oni c Transfect i on Li pi ds For
Use In Liposomal Gene Delivery
Surfactant Science Series (Adsorption And Aggregation Of
Surfactants In Solution) (2003) 109 : 603-617
2003 2003 2003 2003 2003
ALAM, MM, (S)-(-)-1-amino-2-met hoxypyrrolidine (SAMP)
and (R)-(+)-1-amino-2-met hoxypyrrolidine (RAMP) as
versat ile chiral auxiliaries
Synlet t (2003) (11) : 1755-1756
ALAM, MM, (S)-(-)-1-Amino-2-met hoxymet hylpyrrolidine
(Samp ) an d (R )- (+ )- 1- Ami n o - 2 met h o xyme
t hyl pyr rol i di ne (Ramp) as Versat i l e chi ral auxi l l i ar i es
(Sept , Pg. 1755, 2003)
Synlet t (2003) (13) : 2099-2100
ALAM, MM;VARALA, R;ADAPA, SRINIVAS R, Conj ugat e
addi t i on of i ndol es and t hi ol s wi t h el ect ron-def i ci ent
olefins cat alyzed By Bi(OTf )3 -
Tet rahedron Let ters (2003) 44(27) : 5115-5119
ALAM, MM;ADAPA, SRINIVAS R, A f aci l e synt hesi s of
phenylacet ic acids via Willgerodt -Kindler react ion under
PTC Condit ion -
Synt het ic Communicat ions (2003) 33(1) : 59-63
ALAM, MM;VARALA, R;ADAPA, SRINAVAS R, Bi (Ot f )3-
cat al yzed Baeyer - Vi l l i g er o xi d at i o n o f car b o n yl
compounds wit h m-CPBA -
Synthetic Communications (2003) 33(17) : 3035-3040
ANAND, P;SRIDHAR, J;VENKATESWARLU, Ch, Heat release
est i mat o r b ased g l o b al l y l i n ear i zi n g co n t r o l o f a
chemical react or
Indian Journal of Chemical Technology (2003) 10 : 539-544
ANNAPURNA, JETTY;AMARNATH, PVS;KUMAR, DA; RAMA
KRISHNA, SV; RAGHAVAN, KV, Ant i mi crobi al act i vi t y of
Ixora coccinea leaves
Fit ot erapia (2003) 74(3) : 291-293
ANU, SJ;RAO, JM, New norfriedelene-1,3-dione from t he
root bark of Salacia oblonga, Indian Journal of Chemist ry
Sect ion B-Organic Chemist ry Including Medicinal
Chemist ry (2003) 42(5) : 1180-1182
PUBLICATIONS PUBLICATIONS PUBLICATIONS PUBLICATIONS PUBLICATIONS
145
BASAK, P;NISHA, CK;MANORAMA, SV;MAITI, S;JAYA
CHANDRAN, KN, Probi ng t he associ at i on behavi or of
p ol y(et hyl ene gl ycol )-b ased amp hi p hi l i c Comb -l i ke
polymer in NaCl solut ion
Journal of Colloid and Interface Science (2003) 262(2):
560-565
BHASKAR, G;RAO, BV, St ereosel ect i ve synt hesi s of L-
733,060
BHASKARAN, S;SELVANAYAGAM, S;VELMURUGAN, D;
RAVIKUMAR, K; ANNIYAPPAN, M;MURALIDHARAN,
D;PERUMAL, PT, N- (4a- mo r p h o l i n o - 2,3,4,4a,9,9a-
hexahydro-1H-xant hen-9-yl )phenyl ami ne
Act a Cryst allographica , Sect ion E(St ruct ure Report s
Online) (2003) 59(9) : O1301-O1303
BHASKARAN, S;SELVANAYAGAM, S;RAJAKANNAN,
V;VELMURUGAN, D;RAVIKUMAR, K;RASHEED,
AMA;RAJAKUMAR, P, 34,35-dimet hyl-13,20-dioxa-10,23-
d i aza-3,30 d i t hi ap ent acycl o[ 30.4.0.0(4,9).0(14,19).0
(24,29)] hexat ricont a -(36),4,6,8,14,16,18,24,26,28,32,34-
dodecane-11,22-dione
Act a Cryst allographica , Sect ion E(St ruct ure Report s
Online) (2003) 59(9) : O1304-O1306
BHASKARAN, S;SELVANAYAGAM, S;RAJAKANNAN,
V;VELMURUGAN, D;RAVIKUMAR, K;RASHEED, AMA; RAJA
KUMAR, P, 30,31-dimet hyl-3,26-dioxa-11,18- diazapent a
cycl o [26.4.0.0(4,9).0(12,17).0(20,25)] dot ri cont a-1(32),
4,6,8, 12,14,16,20,22,24,28,30- dodecane-10,19-di one -
Act a Cryst allographica, Sect ion E(St ruct ure Report s
Online) (2003) 59(9) : O1429-O1431
BHATTACHARYA, RAJARSHI;PHANIRAJ, TN;SHAILAJA, D,
Pol ysul f one and pol yvi nyl pyrrol i done bl end membra
n es w i t h r ever se p h ase mor p h ol og y as con t r ol l ed
release syst ems: experiment al and t heoret ical st udies
Journal of Membrane Science (2003) 227(1-2) : 23-37
BORUAH, A;RAO,IN;NANDY, JP;KUMAR, SK;KUNWAR,
AC;IQBAL, J, Synt hesi s of a novel ci s-prol i ne-deri ved
cycl i c t yp e VI b et a- t u r n mi mi c vi a Ri n g - cl o si n g
met at hesi s
Journal of Organic Chemist ry (2003) 68(12) : 5006-
5008
BOSE, DS;FATIMA, L;MEREYALA, HB, Green Chemi st r y
approaches t o t he synt hesis of 5-Alkoxycarbonyl-4-aryl-
3,4-Di hydrop yri mi di n-2(1H)-ones by a Three-Comp o
n en t Co u p l i n g o f On e- Po t co n d en sat i o n r eact i o n :
Co mp ar i so n o f Et h an o l , w at er an d so l ven t f r ee
condi t i ons
Journal of Organic Chemist ry (2003) 68(2) : 587-590
BOSE, DS;KUMAR, KK;REDDY, AV, NARSIMHA, A new
p r o t o co l f o r sel ect i ve d ep r o t ect i o n o f N- t er t -
but oxycarbonyl prot ect ive Group (t -boc) wit h Sn(OTf )(2)
BOSE, DS;REDDY, AV NARSIMHA, Iodi ne(V) reagent s i n
organi c synt hesi s. DessMart i n peri odi nane medi at ed
Efficient one-pot oxidat ion of aldehydes t o acyl azides
BOSE, DS;REDDY, AV NARSIMHA;DAS, APR, Si mp l e,
economi cal and envi r onment al l y b eni g n sel ect i ve
regenerat ion of carbonyl compounds from oximes and
N,N-di met hyl hydrazones
Synt hesis-St ut t gart (2003) (12):1883-1885
CHAKRABORTY, TK, Grow a head from wit hin
Current Science (2003) 84(1) : 7
CHARKABORTY, TK;GHOSH, A;KUMAR, SK;KUNWAR, AC,
Nucl eat i on of bet a-Hai rpi n st ruct ures wi t h Ci s Ami de
Bonds in E-Vinylogous Proline-cont aining Pept ides
CHAKRABORTY, TK;GHOSH, A;RAJU, TV, Ef f i ci ent r i ng
opening react ions of N-t osyl aziridines wit h amines and
wat er i n presence of cat al yt i c amount of cer i um(IV)
ammoni um ni t rat e
Publications
146
CHANDRA SEKHAR, K;CHARY, NS;TIRUMALA,
KC;APARNA, V, Det er mi nat i on of t r ace met al s i n sea
wat er by ICP-MS aft er mat rix separat ion
Act a Chimica Slovenica (2003) 50(3) : 409-418
CHANDRA SEKHAR, K;KAMALA, CT;CHARY, NS;
ANJANEYULU, Y, Removal of heavy met als using a plant
biomass wit h reference t o environment al cont rol
Int ernat ional Journal of Mineral Processing (2003)
68(1-4) : 37-45
CHANDRA SEKHAR, K;CHARY, NS;KAMALA,
CT; ANUPAMA, M, Role of cer t ified reference mat erials in
chemical speciat ion st udies
MAPAN Metrology Societ y of India (2003) 18 : 25-35
CHANDRA SEKHAR, S;BABU, BN;REDDY, CHR, Single-st ep
conversion of N-benzyl, N-t rit yl and N-diphenylmet hyl
ami n es t o t - b u t yl car b amat es u si n g p o l ymet h yl
hydrosi l oxane
CHANDRA SHEKAR, S;MURTHY, JK;RAO, PK;RAO, KSR, Pd
sup p or t ed on f l uor i nat ed car b on cover ed al umi na
(FCCA) a h i g h p er f o r man ce Cat al yst i n t h e
hydrodechl ori nat i on of di chl orodi f l uoromet hane
Cat alysis Communicat ions (2003) 4(2) : 39-44
CHANDRA SHEKAR, S;MURTHY, JK;RAO, PK;RAO, KSR, Select ive
hydrogenolysis of dichlorodifluoromet hane on carbon covered
alumina Support ed palladium cat alyst
Journal of Molecular Cat alysis A: Chemical (2003)
191(1) : 45-59
CHANDRA SHEKAR, S; NARASIHMULU, CH; JAGADESHWAR, V;
REDDY, KV ; The f i rst Cor eyChaykovsky epoxi dat i on and
cyclopropanat ion in ionic liquids
CHANDRA SHEKAR, S;NARSIHMULU, CH;REDDY,
NR;REDDY, MS, Triet hylborane t riggered int ermolecular
d omi n o Mi ch ael -al d ol t h r ee-comp on en t Coup l i n g
react i ons
CHAKRABORTY, TK;MOHAN, BK;KUMAR, SK;KUNWAR, AC,
Nucleat ion of bet a-hairpin st ruct ure in a pyrrole amino
acid cont aining pept ide
CHAKRABORTY, TK;LAXMAN, P, Tot al synt hesi s of (+)-
crocacin A
CHAKRABORTY, TK;PURKAIT SUBHAS;DAS, S, Synt hesi s
o f ch i r al 4- h yd r o xy- 2,3- u n sat u r at ed car b o n yl
comp oun d s f r om 3,4-ep oxy al ch ol s b y oxi d at i on :
Applicat ion in t he formal synt hesis of macrosphelide-A
Tet rahedron (2003)59(46):9127-9135
CHAKRABORTY, TK;TAPADAR, S, Synt hesis of (+)-prelact one B
Tetrahedron Letters (2003) 44(12) : 2541-2543
CHAKRABORTY, TK;REDDY, V RAMAKRISHNA;REDDY, T
JAGADESHWAR, Syn t h esi s o f h i g h l y su b st i t u t ed
t et rahydropyrans: preparat i on of t he C20-C28 Moi et y
of phorboxazol es
Tet rahedron (2003) 59(43) : 8613-8622
CHAKRABORTY, TK;SRINIVASU, P;BIKSHAPATHY,
E;NAGARAJ, R; VAIRAMANI, M;KUMAR, SK;KUNWAR, AC
Cyclic homooligomers of furanoid sugar amino acids
6263
CHANDRA SEKHAR, G;RAO, MVP;PRASAD, DHL;KUMAR,
YVLR, Excess mo l ar en t h al p i es o f N,N- d i met h y
lacet amide wit h subst it ut ed benzenes at 298.15 K
Thermochimica Act a (2003) 402(1-2) : 99-103
CHANDRA SEKHAR, K;CHARY, NS;KAMALA, CT;RAO,
J VENKATESWARA; BALARAM, V;ANJANEYULU, Y, Ri sk
assessment and pat hway st udy of arsenic in indust rially
cont aminat ed sit es of Hyderabad: a case st udy
Environment Int ernat ional (2003) 29(5) : 601-611
147
CHANDRA SHEKAR, S;MURTHY, JK;RAO, PK;RAO,
KSR;KEMNITZ, E, Sel ect i ve h yd r o g en o l ysi s o f
di chl orodi fl uoromet hane (CCl
2
F
2
) over CCA support ed
palladium bimet allic cat alyst s
Applied Cat alysis A: General (2003) 224(1) : 39-48
CHANDRA SHEKAR, S;NARSIHMULU, C;SULTANA,
SS;SARITHA, B; PRAKASH, SJ, Solvent and cat alyst free
t hree-component coupl i ng of carbonyl compounds,
Amines and t riet hylphosphit e; a new synt hesis of alpha-
ami nophosphonat es
Synlet t (2003) (4) : 505-506
CHANDRA SHEKAR, S;NARSIHMULU, C;SULTANA,
SS;REDDY, NR, Osmium t et roxide in poly(et hylene glycol)
(PEG): a r ecycl ab l e r eact i o n med i u m f o r r ap i d
asymmet ric dihydroxylat ion under sharpless condit ions
Chemical Communicat ions (2003) (14) : 1716-1717
CHANDRA SHEKAR, S;SRINIVAS, C;SRIHARI, P, Phenyl
sul phonyl acet al dehyde di et hyl acet al : A new robust
1,2-diol prot ect ive group - Synt het ic Communicat ions
(2003) 33(6) : 895-902
CHARY,KVR; RAMESH,K; VIDYASAGAR, G;RAO,VV, Vapour
p h ase al kyl at i o n o f p h en o l w i t h met h an o l o ver
vanadium oxide support ed on zirconia
188(1-2) : 195-204
CHARY, KVR;KISHAN, G;KUMAR, CP;VIDYASAGAR, G;
NIEMATSVERDRIET, JW - Charact erizat ion and react ivit y
of vanadiuim oxide cat alyst s support ed on niobia
CHARY,KVR; KISHAN,G; KUMAR,CP; VIDYASAGAR,G,
St ruct ure and cat al yt i c propert i es of vanadi um oxi de
support ed on al umi na
CHARY, KVR;KISHAN, G;RAMESH, K;KUMAR, CP; VIDYA
SAGAR, G, Synt hesi s, char act er i zat i on and cat al yt i c
proper t i es of Vanadi um oxi de cat al yst s suppor t ed on
AlPO
4
Langmuir (2003) 19(11) : 4548-4554
CHARY, KVR; LAKSHMI, KS;MURTHY, MRVS;RAO,
KSR;PAPADAKI, MARIA, Hydrodechl ori nat i on of 1,2-4-
t richlorobenzene over niobia support ed nickel cat alyst s
CHAUHAN, AS;SRIDEVI, S;CHALASANI, KB;JAIN, AK;JAIN,
SK; JAIN, NK;DIWAN, PV Den d r i mer - med i at ed
t r an sd er mal d el i ver y: en h an ced b i o avai l ab i l i t y o f
i ndomet haci n
Journal of Cont rolled Release (2003) 90(3) : 335-343
CHAUDHURI, A, Cat ionic Transfect ion Lipids-Preface
Current Medicinal Chemist ry (2003) 10(14) : U2-U2
CHOUDARY, BM;MULUKUTLA, RS;KLABUNDE, KJ,
Benzyl at i on of ar omat i c comp ound s wi t h d i f f er ent
cryst allit es of MgO
Journal of t he American Chemical Societ y (2003)
125(8) : 2020-2021
CHOUDARY, BM;JYOTHI, K;MADHI, S;KANTAM, ML,
Cat al yt i c asymmet r i c d i h yd r o xyl at i o n o f al i p h at i c
olefins wit h reusable Resin-osmium t et roxide
Advanced Synthesis & Catalysis (2003) 345(11) : 1190-
1192
CHOUDARY, BM;KANTAM, ML;REDDY, CRV;BHARATHI,
B;FIGUERAS, F, Wad sw o r t h Emmo n s r eact i o n : t h e
unique cat alyt ic react ion by a solid base
Journal of Cat alysis (2003) 218(1) : 191-200
CHOUDARY, BM;REDDY, CRV;PRAKASH, BV;KANTAM,
ML;SREEDHAR, B, The first example of direct oxidat ion
of sulfides t o sulfones by an osmat e Molecular oxygen
syst em
CHOUDARY, BM;KANTAM, ML;RAHMAN, A;REDDY,
VENKAT CHINTA, Sel ect i ve reduct i on of al dehydes t o
alcohols by calcined Ni-Al hydrot alcit e
Journal of Molecular Cat alysis-A : Chemical (2003)
206(1-2) : 145-151
Publications
148
DEVI, P SITA; TLC as a t ool for quant it at ive isolat ion of
conj ugat e t rienoic FA
Journal of American Oil Chemist s Societ y (2003) 80(4)
: 315-318
DEVI, SS;MALATHI, R;RAJAN, SS;ARAVIND, S;KRISHNA
KUMARI, GN; RAVIKUMAR, K; A new clerodane dit erpene
wi t h ant i feedant act i vi t y from Teucri um t oment osum,
Act a Cryst allographica - Sect ion C
Cryst al St ruct ure Communicat ions (2003) 59(9) :
O530-O532
DHEVI, DM;PRIYAKUMAR, UD;SASTRY, GN; Silaaromat icit y
in polycyclic syst ems: A comput at ional st udy
1171
DINADAYALANE, TC;GEETHA, K;SASTRY, GN; Ab init io and
d en si t y f u n ct i o n al t h eo r y (DFT) st u d y o n [ 1,5]
si gmat ropi c, Rearrangement s i n pyrrol es, phosphol es,
and siloles and t heir Diels-Alder react ivit ies,
Journal of Physical Chemist ry- A (2003) 107(28) :
5479-5487
DINADAYALANE, TC;DEEPA, S;SASTRY, GN; Is p er i
hydrogen repul si on responsi bl e f or f l at t eni ng bucky
bowls? The effect of Ring annelat ion t o t he rim of coran
nulene,
Tet rahedron Let t ers (2003) 44 (24) : 4527-4529
DINADAYALANE, TC; PUNNAGAI, M;SASTRY, GN; A
t heoret i cal st udy on cycl oaddi t i on react i ons bet ween
[c]-annelat ed het erocyclic Five-membered dienes and
acet yl ene,
Journal of Molecular St ruct ure: THEOCHEM (2003)
626(1-3) : 247-262
DINADAYALANE, TC;SASTRY, GN; Isolat ed pent agon rule
i n buckybowl s: a comput at i onal st udy on t hermody
namic st abilit ies and bowl-t o bowl inversion barriers
Tet rahedron (2003) 59(42) : 8347-8351
CHOUDARY, BM;SOMESHWAR,T;REDDY, ChV;KANTAM, M
LAKSHMI; RATNAM, JEEVA, K;SIVAJI, LV, The first example
of bromi nat i on of aromat i c compounds wi t h unprece
dent ed at om Economy using molecular bromine
CHOUDARY,BM;CHOWDARI,NS;JYOTHI, K;KANTAM, ML,
Het er o g en eo u s cat al yt i c asymmet r i c ami n o h y
droxylat ion of olefins using LDH-Support ed OsO
4
196(1-2) : 151-156
CHOUDARY, BM;CHOWDARI, NS;MADHI, S;KANTAM ,ML,
A t ri f unct i onal cat al yst f or one-pot synt hesi s of chi ral
d i o l s vi a Heck co u p l i n g - N- Oxi d at i o n - asymmet r i c
d i h yd r o xyl at i o n : ap p l i cat i o n f o r t h e syn t h esi s o f
dilt iazem And t axol side chain
DANADEVI,K; ROZATI,R; BANU,BS; RAO,PH;GROVER,P,
DNA damage in workers exposed t o lead using comet
assay
Toxicology (2003) 187(2-3) : 183-193
DANADEVI, K;ROZATI, R;REDDY, PP;GROVER, P, Semen
qual i t y of Indi an wel ders occupat i onal l y exposed t o
nickel and chromium
Reproduct ive Toxicology (2003) 17(4) : 451-456
DAS, B;BANERJEE, J;RAMU, R;PAL, R;RAVINDRANATH,
N;RAMESH, C; Ef f i ci en t , sel ect i ve d ep r o t ect i o n o f
aromat ic acet at es cat alyzed by Amberlyst -15 or iodine
DAS, B;KASHINATHAM, A;VENKATAIAH, B;SRINIVAS, KVNS;
MAHENDER, G;REDDY, MR Cleomiscosin A, a coumarino-
lignoid from Jat ropha gossypi fol i a
Biochemical Syst emat ics and Ecology (2003) 31(10) :
1189-1191
DEVI, BLAP;KARUNA, MSL;RAO, KN;SAIPRASAD,
PS;PRASAD, RBN; Mi crowave-assi st ed cat al yt i c t ransfer
hydrogenat ion of safflower oil
Journal of t he American Oil Chemist s Societ y (2003)
80(10) : 1003-1005
149
DINADAYALENE, TC; SASTRY, GN; Densi t y f unct i onal
t heory st udy on dimerizat ions of phospholes,
Organomet allics (2003) 22(26) : 5526-5533
DURGAKUMARI, V;SAROJA, G;RATNAMAL,
A;SUBRAHMANYAM; Vapour phase acylat ion of phenol
over HB, CeHB and SO
4
2-
/ ZrO
2
React ion Kinet ics & Cat alysis Let t ers (2003) 79 : 43-51
ETTI, S; SHANMUGAM, G;PONNUSWAMY, MN;SRIDHAR,
R;MURUGAN, R; PERUMAL, PT;RAVIKUMAR, K; Et hyl 3-
met hyl-1-(2,4-dinit rophenyl)-1H-pyrazole-4-carboxylat e
Act a Cryst allographica , Sect ion E (St ruct ure Report s
Online) (2003) 59(Part 11) : O1835-O1837
FADNAVIS, NW;BHASKAR, V;KANTAM, ML;CHOUDARY,
BM; Highly efficient Tight Fi t Immobilizat ion of alpha-
Ch ymo t r yp si n i n Meso p o r o u s, MCM- 41: A n o vel
ap p r o ach u si n g Pr ecu r so r i mmo b i l i zat i o n an d
act i vat i on
Biot echnology Progress (2003) 19(2) : 346-351
FADNAVIS, NW;SHEELU, G;KUMAR, BM;BHALERAO,
MU;DESHPANDE, AA; Gelat in blends wit h alginat e: gelsfor
lipase immobilizat ion and purificat ion
Biot echnology Progress (2003) 19(2) : 557-564
GADI, R;KULSHRESTHA, UC;SARKAR, AK;GARG,
SC;PARASHAR, DC; Emi ssi ons of SO2 and NOx f rom
biofuels in India Tellus Series B
Chemical & Physical Met eorology (2003) 55(3) : 787-
795
GEETHA, K;DINADAYALANE, TC;SASTRY GN; Ef f ect of
met h yl an d vi n yl sub st i t ut i on on t h e g eomet r i es,
r el at i ve st ab i l i t i es an d Di el s- Al d er r eact i vi t i es o f
phospholes: a DFT st udy
Journal of Physical Organic Chemist ry (2003) 16(5) :
298-305
GEORGE, JOHN;SASTRY, NV;PRASAD, DHL; Excess molar
ent halpies and excess molar volumes of met hyl met ha
cr yl at e, +benzene+Tol uene+P-xyl ene,+ cycl ohexane
an d + al i p h at i c d i et h er s (d i et h yl , d i i sop r op yl an d
di but hyl )
Fluid Phase Equlibria (2003) 214(1) : 39-51
GNANAKUMARI, P;RAO, MVP;PRASAD, DHL;KUMAR,
YVLR; Vap o r - l i q u i d eq u i l i b r i a an d excess mo l ar
en t h al p i es f o r N- met h yl - 2- p yr r o l i d o n e w i t h
chl oroet hanes and chl oroet henes
Journal of Chemical and Engineering Dat a (2003)
48(3), 535-540
GOPINATH, N RAJESH;LINGAIAH, B;SREEDHAR,
B;SURYANARAYANA, I; PRASAD, PS SAI;OBUCHI, AKIRA;
Highly st able Pd/ CeO2 cat alyst for hydrodechlorinat ion
of chl orobenzene
Applied Cat alysis B: Environment al (2003) 46(3) :
587-594
GOPINATH,R;LINGAIAH, N;SURYANARAYANA, I;PRASAD,
PSS; St u d i es o n mi cr o w ave i r r ad i at ed Pd / Nb 2O5
cat alyst s: Effect of palladium chloride precursor on t he
chl orobenzene hydrodechl ori nat i on act i vi t y
Reaction Kinetics & Catalysis Letters (2003) 79(1) : 61-67
GOUD, T VENKATESWAR;SRINIVASULU, M;REDDY, VLNR;
REDDY, ADELLI V;RAO, TP;KUMAR, DS;MURTY, U
SURYANARAYANA;VENKATESWARLU, Y; Tw o n ew
Bromot yrosi ne deri ved met abol i t es f rom t he Sponge
Psammapl ysi l a Purpurea
Chemical and Pharmaceut ical Bullet in (2003) 51(8) :
990-993
GOUD, T VENKATESWAR; REDDY, N SRINIVASA;SWAMY,
NR;TEJOMOORTULA, SIVA RAM; VENKATESWARLU, Y;
Ant i -HIV act i ve p et r osi ns f r om t he mar i ne sp ong e
Pet rosia similis
Biological and Pharmaceut ical Bullet in (2003) 26(10)
: 1498-1501
GOVIND, MM;SELVANAYAGAM, S;VELMURUGAN,
D;RAVIKUMAR, K;SRIDHAR, G;RAGHUNATHAN, R; 4 -(p-
Met h ox yp h enyl )-1 - met h yl - 1H- i n d o l e- 3- sp i r o - 2 -
pyrrolidine- -spiro-1 -cyclopent ane-2(3H),2 dione
Online) (2003) 59(Part 10):O1438-O1440
Publications
150
JAYANTY, S;PRASAD, GK;SREEDHAR, B;RADHAKRISHNAN,
TP; Po l yel ect r o l yt e t emp l at ed p o l yan i l i n e- f i l m
morphol ogy and conduct i vi t y
Polymer (2003) 44(24) : 7265-7270
KAMAL, A;CHOUHAN, G; Chemosel ect i ve t hi oacet al i
zat i o n an d t r an st h i o acet al i zat i o n o f car b o n yl
compounds cat al yzed by i mmobi l i zed scandi um(III)
t riflat e in ionic liquids,
KAMAL, A;KHANNA, GBR;RAMU, R;KRISHNAJI, T; Chemo
enzymat ic synt hesis of duloxet ine and it s enant iomer:
l i pase-cat al yzed Resol ut i on of 3-hydroxy-3-(2-t hi enyl )
propaneni t ri l e
KAMAL, A;KUMAR , B ASHWINI;ARIFUDDIN, M; A one-pot ,
efficient and facile synt hesis of 4b-arylaminopodophy
l l o t o xi n s: Syn t h esi s o f NPF an d GL- 331 as DNA
t opoi somerase II i nhi bi t ors
KAMAL, A;RAMANA, K VENKATA;RAMANA, A VENKATA;
HARI BABU, A; Ch emoen zymat i c en an t i o sel ect i ve
syn t h esi s o f 3- h yd r o xy- 2- p yr r o l i d i n o n es An d 3-
Hydroxy-2-pi perdi nones
Tet rahedron: Asymmet ry (2003) 14(17) : 2587-2594
KAMAL, A;RAMESH, G;RAMULU, P;SRINIVAS, O;REHANA,
TASNEEM; SHEELA, G; Desi gn and synt hesi s of novel
chrysene-l i nked p yrrol o[ 2,1-c] [ 1,4] -b enzodi azep i ne
Hybrids as pot ent ial DNA-binding agent s
Bioorganic and Medicinal Chemist ry Let t ers (2003)
13(20) : 3451-3454
KAMAL, A;RAMULU, P;SRINIVAS, O;RAMESH, G; Synt hesis
of C-8 met hanesul p honat e sub st i t ut ed p yr r ol ob en
zodiazepines as Pot ent ial ant it umour agent s
Bio organic and Medicinal Chemist ry Let t ers (2003)
13(20) : 3517-3519
D;RAVIKUMAR, K; SRIDHAR, ;RAGHUNATHAN, R; 1N-
Met hyl-spiro[2-3 ]indan-1,3-dione-spiro[3-3 ]-5 -benzy
lidene-N-met hyl-piperidinone-4-phenylpyrr olidine
Online) (2003) 59 (Part 11):O1680-O1681
D;RAVIKUMAR, K;DURGA, RR;RAGHUNATHAN, R; 1,2,3,4-
Tet rahydro-4 -f ur f ur yl -1 -met hyl napht hal ene-2-spi ro-
3-pyrrolidine-2 -spiro-1 -acenapht hene-1,2 -dione
Online) (2003) 59(Part 12):O1875-O1877
D;RAVIKUMAR, K; SRIDHAR, G;RAGHUNATHAN, R; 5 -
Benzyl i dene-1 -met hyl -4 -p henyl i ndol e-3-sp i r o-2 -
pyrrolidine-3-spiro-3 -piperidine-2(3H),4 -dione
Online) (2003) 59(Part 12):O1878-O1880
GROVER, P;DANADEVI, K;MAHBOOB, M;ROZATI, R;BANU, BS;
RAHMAN, MF; Eval uat i on of genet i c damage i n workers
employed in pest icide product ion Ut ilizing t he Comet
Assay Mut agenesis (2003) 18(2) : 201-205
HEYDORN, LN;WONG, CY;SRINIVAS, R;TERLOUW, JK; The
isobaric ions CH
3
OP=O.
+
and CH
3
OPNH
2
+
and t heir
neut ral Count erpart s: a t andem mass spect romet ry and
CBS-QB3 comput at i onal st udy
Int ernat ional Journal of Mass Spect romet ry (2003)
225(1) : 11-23
JAYACHITRA, G;YASMEEN, N;RAO, KS;RALTE,
SL;SRINIVASAN, R; SINGH, AK; Boront rifluoride et herat e
promot ed one-pot conversion of nit riles t o est ers
JAYALAKSHMI, M;RAO, MM;SCHOLZ, F; El ect rochemi cal
b ehavi or of sol i d l i t hi um manganat e (Li Mn2O4) i n
aqueous neut ral el ect rol yt e sol ut i ons
Langmuir (2003) 19(20) : 8403-8408
151
KAMAL, A;RAMULU, P;SRINIVAS, O;RAMESH, G; Synt hesis
and DNA-bi ndi ng af f i ni t y of A-C8/ C-C2 al kaxyami do-
linked pyrrolo [2,1-C][1,4] benzodiazepine dimers
Bioorganic & Medicinal Chemist ry Let t ers (2003)
13(22) : 3955-3958
KAMAL, A;REDDY, PSMM;REDDY, DR; An efficient cat alyt ic
deprot ect ion of t hioacet als employing bismut h t riflat e:
Synt hesis of pyrrolo[2,1-c] [1,4] benzodiazepines
KAMAL, A;REDDY, L;DEVAIAH, V;REDDY, GSK; Faci l e
reduct ion of aromat ic nit ro/ azido funct ionalit y on solid
su p p o r t emp l o yi n g Al / Ni Cl 26H2O an d Al / NH4Cl :
synt hesi s of pyrrol o[2,1-c][1,4]benzodi azepi nes
KAMAL, A;SANDBHOR, M;SHAIK, AA; Appl i cat i on of a
one-pot lipase resolut ion st rat egy for t he synt hesis of
chiral And lact ones
KAMAL, A;SANDBHOR, M;SHAIK, ALI AHMED;SRAVANTHI,
V; One-pot synt hesi s and resol ut i on of chi ral al l yl i c
al cohol s
Tet rahedron Asymmet ry (2003) 14(18) : 2839-2844
KAMAL, A;SANDBHOR, M;AHMED, KALEEM;ADIL,
SF;SHAIK, AHMAD ALI; Chemoenzymat i c synt hesi s of
enant iomerically pure t erminal 1,2-diols
KAMAL, A;SRINIVAS, O;RAMULU, P;RAMESH, G;KUMAR,
P PRAVEEN; Synt hesis of novel C2 and C2 – C8
l i n ked p yr r o l o [ 2,1- c] [ 1,4] Ben zo d i azep i n e-
Napht halimide hybrids as DNA-binding agent s
13(20) : 3577-3581
KAMAL, A;ASHWINI KUMAR, B; ARIFUDDIN, M; DASTIDAR,
SUNANDA G; Synt hesi s of 4b et a-ami do and 4b et a-
su l p h o n ami d o an al o g u es o f p o d o p h yl l o t o xi n as
pot ent i al ant i t umour agent s
Bioorganic and Medicinal Chemist ry (2003) 11(23) :
5135-5142
KANTAM, M LAKSHMI;HARITHA, Y;REDDY, NM;
CHOUDARY, BM; FIGUERAS, F; Cl ar i f i cat i on f or t h e
comment s on our ar t i cl e Cycl opropanat i on of ol efi ns
Usi n g a si l i ca g el an ch o r ed p al l ad i u m p h o sp h i n e
complex Cat al. Let t , 83, 187, 2002 by Jose M. Fraile, Jose
I. Gar ci a, and Jose A. Mayoral , Cycl op r op anat i on of
olefins wit h het erogeneous cat alyst s
Cat al. Let t , 88, 31, 2003 Cat alysis Let t ers (2003) 90(3-
4) : 231
KANTHAM, M LAKSHMI;JAYALAKSHMI, KAK;LIKHAR, PR;
Bis(Cyclopent adienyl) zirconium dichloride, an efficient
cat al yst f or hi ghl y sel ect i ve Format i on of bet a-al koxy
alcohols via ring opening of 1,2-epoxides wit h alcohols
Cat alysis Let t ers (2003) 89(1-2) : 95-97
KANTHAM, M LAKSHMI;KAVITHA, B;NEERAJA, V;HARITHA,
Y; CHAUDHURI, MK; DEHURY, SK;Mi cr oen cap sul at d
Cu (acac)
2
: a r eco ver ab l e an d r eu sab l e p o l ymer -
support ed copper cat alyst for aziridinat ion of olefins
KARLE, I; GILARDI, RD;RAO, CC; MURALEEDHARAN,
KM;RANGANATHAN, S; Unique assemblies of alt ernat ing
posi t i vel y and negat i vel y charged l ayers, di rect ed by
hydrogen bonds, ionic int eract ions, and pi-st acking in
t he cryst al st ruct ures of compl exes bet ween mel l i t i c
aci d (b enzenehexacar b oxyl i c aci d ) and f i ve p l anar
aromat i c bases
Journal of Chemical Cryst allography (2003) 22 (10) :
727-749
KARLE, I;RANGANATHAN, D; Const ruct ion of polar and
hydrophobic pores and channels by assembly of Pept ide
mol ecul es
Journal of Molecular Structure (2003) 647(1-3) : 85-96
KAZINCZY, B;KOTAI, L;GACS, I;SAJO, IE;SREEDHAR,
B;LAZAR, K; St udy of t he preparat i on of zi nc(II) f erri t e
and ZnO f r om zi nc- and i r on-cont ai ni ng Ind ust r i al
wast es
Industrial and Engineering Chemistry Research (2003)
42(2) : 318-322
Publications
152
KULSHRESTHA, MJ;KULSHRESTHA, UC;PARASHAR,
DC;VAIRAMANI, M; Est i mat i on of SO4 cont ri but i on by
dry deposit ion of SO2 ont o t he dust Part icles in India
Atmospheric Environment (2003) 37(22) : 3057-3063
KUMAR, AR;BHASKAR, G;MADHAN, A;RAO, BV;
St ereosel ect i ve synt hesi s of (-)-cyt oxazone and (+) 5-
epi -cyt oxazone
KUMAR, AR;RAO, BV; An efficient synt hesis of prot ect ed
(2R,3R,4S)-4,7-di ami ns-2,3-di hydroxyhept anoi c Aci d, A
const it uent of callipelt ins A&D
KUMAR, AR;REDDY, JS;RAO, BV; A shor t , si mp l e and
g en er al ap p r o ach f o r t h e syn t h esi s o f (3S,4S)- 3-
met hoxy-4-met hyl ami no Pyrrol i done
KUMAR, AS;HARITHA, B;RAO, BV; A versat ile and efficient
synt hesis of (2S)-2-(hydroxymet hyl)-N-Boc-2,3-Dihydro-
4-pyri done
KUMAR, HMS;RAO, MS;JOYASAWAL, S;YADAV, JS;
Condensat ion of ort hoacet at es wit h aldehydes: a new
st rat egy for t he Preparat i on of ,-unsat urat ed est ers
KUMAR, VV;SINGH, RS;CHAUDHURI, A; Cat i o n i c
Transf ect i on Li pi ds i n Gene Therapy: Successes, Set -
backs, Challenges and Promises
Current Medicinal Chemist ry (2003) 10(14) : 1297-
1306
KUMAR, VV;PICHON, C;REFREGIERS, M;GUERIN,
B;MIDOUX, P; CHAUDHURI, A; Si n g l e Hi st i d i n e
f unct i onal i t y i s suf f i ci ent t o i mpart remarkabl e gene
t ransfect ion propert ies t o Cat ionic Lipids: Evidence for
membrane fusion at acidic pH
Gene Therapy (2003) 10(15) : 1206-1215
KIRUMAKKI, SR; NAGARAJU, N;CHARY, KVR;NARAYANAN,
S Kinet ics of est erificat ion of aromat 0ic carboxylic acids
over zeolit es H and HZSM5 using dimet hyl carbonat e
Applied Cat alysis A: General (2003) 248(1-2) : 161-
167
KISHORE, PH;REDDY, MVB;GUNASEKAR, D;MURTHY,
MM;CAUX, C; BODO, B; A n ew co u mest an f r o m
Tephrosi acal ophyl l a
194-196
KRISHANAVENI, NS;SURENDRA, K;REDDY, MA;
NAGESHWAR, YVD; RAO, KR; Highly efficient reproduct ion
of aromat ic acet als and neut ral condit ions using Bet a-
cyclodext rin in wat er
Journal of Organic Chemist ry 2003 68(5) : 2018-2019
KRISHNAVENI, NS;SURENDRA, K;NAGESWAR, YVD;RAO,
KR; Deoximat ion of oximes wit h 2-iodylbenzoic acid in
wat er in t he presence of bet a-cyclodext rin
Synt hesis St ut t gart (2003) (13) : 1968-1970
KRISHNAVENI, NS;SURENDRA, K;NAGESWAR, YVD;RAO,
KR; Mild and efficient hydrolysis of aromat ic t hioacet als/
t hioket als using o-iodoxybenzoic acid (IBX) in presence
bet a- cyclodext rin in wat er
KOTAI, L;GACS, I;KAZINCZY, B;SAJO,IE;SREEDHAR, B;
Quasi -i nt ramol ecul ar aci d-base react i ons i n aqueous
so l u t i o n s o f met al - Co mp l exes o f b asi c l i g an d s I.
Gen er al i zed t h eo r et i cal co n si d er at i o n s o n t h e
deammoniat ion of [MLm] X-n t ype ammonia complexes
Transit ion Met al Chemist ry (2003) 28(3) : 292-295
KULSHRESTHA, UC;KULSHRESTHA, MONIKA J;SEKAR,
R;SASTRY, GSR; VAIRAMANI, M; Chemical charact erist ics
of rainwat er at an urban sit e of sout h cent ral India
Atmospheric Environment (2003) 37(21) : 3019-3026
153
KUMARASWAMY, G;RAMESH, S; So aked Ph aseo l u s
au r eu s L: an ef f i ci en t b i o cat al yst f o r asymmet r i c
reduct ion of prochiral aromat ic ket ones
Green Chemist ry (2003) 5(3) : 306-308
KUMARASWAMY, G;SASTRY, MNV;JENA, N;KUMAR,
KR;VAIRAMANI, M; En an t i o en r i ch ed (S)- 6,6 -
diphenylbinol-Ca: a novel and efficient chirally modified
met al co mp l ex f o r asymmet r i c ep o xi d at i o n o f
al pha,bet a-unsat urat ed enones
Tet rahedron-Asymmet ry (2003) 14(23):3797-3803
KUMARASWAMY, G;DAS, AK;JENA, N; A r el i ab l e
mult igram synt hesis of (+/ -) doxazosin
Organic Preparat ions and Procedures Int ernat ional
(2003) 35(6) : 603-608
KUMARI, GN KRISHNA;ARAVIND, S;BALACHANDRAN,
J;GANESH, MR; SOUNDARYA DEVI, S;MALATHI,
R;RAVIKUMAR, K; Ant i f eedant neo-cl eor odanes f rom
Teucri um t oment osum Heyne(Labi at ae)
Phyt ochemist ry (2003) 64(6) : 1119-1123
MADHAN, A;RAO, BV; St ereosel ect i ve synt hesi s of 1,4-
d i d eoxy-1,4-i mi no-D-al l i t ol and f or mal Synt hesi s of
(2S,3R,4S)-3,4-di hydroxyprol i ne
Tetrahedron Lett ers (2003) 44(30) : 5641-5643
MADHAVI, G;KULKARNI, SJ;MURTHY, KVVSBSR; VISWA NATHAN, V;
RAGHAVAN, KV; Si d e-chai n al kyl at i on of 4-p i col i ne wi t h
formaldehyde over alkali-modified Zeolit es
MAHENDER, G;RAMU, R;RAMESH, C;DAS, B; A simple and
f aci l e ch emo - an d r eg i o sel ect i ve d ep r o t ect i o n o f
acet oni des usi ng si l i ca support ed sodi um hydrogen
sul fat e as a het erogeneous cat al yst
MAHESWARI, R;SHANTHI, K;SIVAKUMAR, T;NARAYANAN,
S; Mesoporous molecular sieves: Part 1. Isopropylat ion
of napht halene over AlMCM-41
MAHESWARI, R; HANTHI, K; IVAKUMAR, T; ARAYANAN, S;
Beckmann rearrangement over phosphot ungst ic acid/
SiMCM-41 cyclohexanone oxime t o -caprolact am
Applied Cat alysis A: General (2003) 248(1-2) 291-301
MANJULA, A; AO, BV; EELAKANTAN, P; One pot synt hesis
of a -Aminophosphonat es: An inexpensive approach
MANJULA, A;REDDY, GN;RAO, BV; Oxidat ive deoximat ion
wi t h cat al yt i c sodi um t ungst at e
MEHTA, G;SINGH, SR;PRIYAKUMAR, UD;SASTRY, GN; The
t ricyclo[2.1.0.0
2,5
]pent an-3-one syst em: a new probe for
t he st udy of -facial select ivit y in nucleophilic addit ions
MEREYALA, HB;POLA, P; Cont rol l ed acet ol ysi s of 3,6-
an h y d r o - 5 - o - b en zy l - 1 , 2 - o - i so p r o p h l i d en e- A- D
g l u co f u r an o se: Syn t h esi s o f 1- (3,6 - an hyd r o - A- D-
gl ucof uranosyl ) t hymi ne
MEREYALA, HB;MAMIDYALA, SK;CHIGURUPATI, KP;
SRINIVASA, SR; Di scr i mi n at i v e g l yco syl at i o n o f 3-
(aryloxy)propane-1,2-diols by choice of a glycosyl donor
MEREYALA, HB;BANTU, R; Synt hesis of met hyl 3-deoxy-
alpha/ bet a D-ribofuranoside by regioselect ive reduct
i ve op en i n g of met h yl 2,3-an h yd r o-al p h a/ b et a-D-
ribofuranoside - Indian Journal of Chemist ry Sect ion B
Organic Chemist ry Including Medicinal Chemist ry
(2003) 42(12) : 3071-3074
MEREYALA, HB;POLA, P; Resolut ion of 1-Arylet hylamines
w i t h 5-(1,2-0-Isop r op yl i d ene-3,6-anhyd r o-al p ha D-
gl ucof uranosyl ) hydrogen pht hal at e
Publications
154
MOHAN, SR;RAO, A RAMAKRISHNA; Early ident ificat ion
of i nnovat i ve and market accept abl e t echnol ogi es: a
model f or i mprovi ng t echnol ogy t ransf er capabi l i t i es
in public research inst it ut e
Journal of Scient ific & indust rial Research (2003)
62(9): 865-875
MOHAN, SR;KRISHNA, D;MURTHY, BSN;RAO, A
RAMAKRISHNA; Pr o d u ct i vi t y eval u at i o n o f p u b l i c
research i nst i t ut e usi ng fact or anal ysi s
Indust rial Engineering (2003) 32(9) : 22-28
MOHAN, SR; Tech n ol ogy i n cub at or s-A st r at eg y f or
commercializing knowledge of public R&D Inst it ut es
Pharma Bio World (2003) 2(2) : 72-80
MOHAN, SR;MAHENDRANATH, D; Ap p l i cat i o n o f
st at ist ical modeling in invent ory management of a Ware
House
Indust rial Engineering Journal (2003) 32(3) : 2-4
Moh an , SV;Si st l a, S;Gu r u, RK;Pr asad , KK;Ku mar, CS;
Ramakri shna, SV;Sarma, PN; Mi crobi al degradat i on of
pyridine using Pseudomonas sp. and isolat ion of Plasmid
responsi bl e for degradat i on
Waste Management (2003) 23(2) : 167-171
MOHAN, SV;RAO, NC;PRASAD, KK;KARTHIKEYAN, J;
Errat um t o Treat ment si mul at ed react i ve yel l ow 22
(Azo) dye ef f l uent s usi ng Spi r ogyra sp eci es [ Wast e
Management , 22(6) 575582 (2002)]
Wast e Management (2003) 23(2) : 195
MOHAN, SV;SARMA, PN; Hazardous wast e management
an d t r eat men t t ech n o l o g i es i n p h ar maceu t i cal
i ndust ri es
Pharma Bio World (2003) 2(4) : 134-140
MOHAN, SV;SARMA, PN; Sel ect i o n o f ap p r o p ei at e
p h ysi o ch emi cal t r eat men t t ech n o l o g i es f o r
pharmaceut i cal wast ewat er
Pharma bioworld (2003) 2(3) : 82-86
MESHARAM, HM;GANESH, YSS;MADHAVI, AV; ESHWARAIAH, B;
YADAV, JS;GUNASEKAR, D; Clay suppor t ed ammoni um
ni t rat e Cl ayan : A new reagent for sel ect i ve Ni t rat i on
of arenas
MESHRAM, HM;REDDY, GS;REDDY, MM;EESHWARAIAH,
B;YADAV, JS; Mi crowave t her mol ysi s: Par t III - A rapi d
and convenient coupling of2-napht hols in solvent -free
condi t i on
I ndi an Jour nal of Chemi st r y Sect i on B, Or gani c
Chemi st ry I ncl udi ng Medi ci nal Chemi st ry (2003)
42(10) : 2615-2617
MIRZA, SP;KRISHNA, P;PRABHAKAR, S;VAIRAMANI,
M;GIBLIN, D; GROSS, L MICHAEL The ki net i c met hod
reveal s secondary deut eri um i sot ope ef f ect s on t he
prot on af f i ni t y and gas-phase basi ci t y of gl yci ne and
al ani ne met hyl est ers
230(2-3) : 175-183
MOHAN, K CHANDRA;RAVIKUMAR, K;SHETTY, MM;
Cryst al st ruct ures of t wo subst it ut ed key int ermediat es
of phenot hi azi ne Deri vat i ves
Journal of Chemical Cryst allography (2003) 33(2) :
97-103
MOHAN, K CHANDRA;RAVIKUMAR, K;SHETTY, MM;
THIYAGARAJAN, S; RAJAN, SS; Cr yst al and mol ecul ar
st r u ct u r es o f 1,4- d i h yd r o - 6- met h yl - 5- N,N- d i et h yl
carbamoy l -4-phenyl -2(3H)-pyri mi di net hi on e (1) and
1,4-d i hyd r o-6-met hyl -5-N-met hyl car b amoyl -4-(2 -
ni t rophenyl )-2(3H)-pyri mi di net hi one hemi hydrat e (2)
Journal of Chemical Cryst allography (2003) 33(2) :
113-121
MOHAN,K CHANDRA;RAVIKUMAR, K;SHELLY, MM;
VELMURUGAN, D; Cryst al and mol ecul ar st ruct ures of
4-aryl -1,4-di hydropyri mi di nes: Novel cal ci um channel
ant agoni st s
Zeit schrift fur Krist allographie (2003) 218(1) : 46-55
155
MOHAN, SV;SARMA, PN; Anaerobic t reat ment process
for pharmaceut i cal wast ewat er
Pharma bioworld (2003) 2(1) : 101-108
MOIZUDDIN, Md;VENKATESWARLU, Ch; Temp er at ur e
Traj ect or y Tracking of a Chemical React or using Fuzzy
linguist ic Cont roller
Indian Chemical Engineering Sect ion A (2003) 45(2) :
84-87
MOULI, PC;MOHAN, SV;REDDY, SJ; A st ud y on maj or
inorganic ion composit ion of at mospheric aerosols at
Ti rupat i
Journal of Hazardous Materials (2003) 96(2-3) : 217-228
MURTY, MSR;JYOTHIRMAI, B;KRISHNA, PR;YADAV, JS; Zinc
mediat ed alkylat ion of cyclic secondary amines
NACHARAYA, YV;WATTIAU, P;WERUTZ, S;BATHE,
S;MOHAN, SV;WILDERER, PA;HAUSNER, M; Dual labeling
of Psedomonas put i da wi t h f l uroscent prot ei ns f or i n
sit u monit oring of conj ugal t ransfer of TOL plasmid
Applied Environment al Microbiology (2003) 69(8) :
4846-4852
NAGARAJA, BM;KUMAR, VS;SHASIKALA, V;PADMASRI,
AH;SREEDHAR, B; RAJU, BD;RAO, KSR; A highly efficient
Cu/ MgO cat al yst f or vapour phase hydrogenat i on of
f urf ural t o f urf uryl al cohol
Catalysis Communications (2003) 4(6) : 287-293
NAGARAJU, V;SREENATH, D;RAO, JT;RAO, RN; Separat ion
an d d et er mi n at i o n o f syn t h et i c i mp u r i t i es o f
sildenafil(vliagra) by reversed-phase high-performance
l i qui d chromat ography
Analyt ical Sciences (2003) 19(7) : 1007-1011
NAGRAPU, L;NARENDER, R;SUCHETA, K; Benzot hiazepine
fused het erocycles VI: A convenient synt hesis of 2-aryl-
4 (4-hydroxy-6-met hyl-2-pyrone-3-yl)-2,3-dihydro-1, 5-
benzot hiazepines using MCM-41(H) zeolit e
Het erocyclic Communicat ions (2003) 9(1) : 35-38
NARAYANAN, S; Select ive hydrogenat ion of unsat urat ed
al dehydes and ket ones
Bullet in of t he Cat alysis Societ y of India (2003) 2 :
107-121
NAIR, VIJAY;MATHEW, B;VINOD, AU;MATHEN, JS;ROS,
S;MENON, RS; VARMA, R L SRINIVAS, R; [4+1] cycloaddit ion
react i ons of o-t hi oqui nones wi t h i socyani des: Novel
synt heses of 2-imino-1,3-oxat hioles
Synt hesis-St ut t gart (2003) (5) : 662-664
NAIR, VIJAY;SREEKANTH, AR;ABHILASH, N;BIJU, AT;DEVI,
BR; MENON, RS;RATH, NP;SRINIVAS, R; Novel pyri di ne-
cat alyzed react ion of dimet hyl acet ylenedicarboxylat e
wi t h al dehydes and N-t osyl i mi nes: Ef f i ci ent synt hesi s
of 2-enzoylfumarat es and 1-azadienes
Synt hesis-St ut t gart (2003) (12):1895-1902
NAIR, VIJAY;VINOD, N UNNI;RAJEEV, S ABHILASH;MENON,
V;VARMA, SANTHI R LUXMI;VIJI, S;MATHEW,
SAUMINI;SRINIVAS, R; Mu l t i comp o n en t r eact i o n s
i n vo l vi n g zw i t t er i o n i c i n t er med i at es f o r t h e
const ruct ion of het erocyclic syst ems: one pot synt hesis
of ami nofurans and i mi nol act ones
Tet rahedron (2003) 59(51) : 10279-10286
NAIR, VIJAY;BALAGOPAL, L;MENON, RS;ROS, S;SRINIVAS,
R; Oxi dat i ve i nt r amol ecul ar cycl i zat i on r eact i ons of
ci nnamyl et hers medi at ed by ceri um(IV) ammoni um
ni t rat e (CAN): a st ereosel ect i ve synt hesi s of 3,4-t rans-
di subst i t ut ed t et rahydrof uran deri vat i ves
Arkivoc (2003) (Part 8):199-210
NANDA, S;YADAV, JS; Asymmet ric synt hesis of unnat ural
(Z,Z,E)- o ct ad ecat r i an o i d an d Ei co sat r i en o i d b y
l i poxygenase-cat al yzed oxygenat i on
NANDY, JP;PRABHAKARAN, EN;KUMAR, SK;KUNWAR,
AC;IQBAL, J; Reverse t urn i nduced pi -f aci al sel ect i vi t y
during polyaniline-support ed cobalt (II) salen cat alyzed
aerobi c epoxi dat i on of N-ci nnamoyl L-prol i ne deri ved
pept i des
1692
Publications
156
PALANIAPPAN, S;AMARNATH, CA; Pyr i di ni um chl or o
chromat e oxidat ion rout e t o polyaniline
Polymers for Advanced Technologies (2003) 14(2) :
122-128
PALANIAPPAN, S;NARENDER, P;SARAVANAN, C;RAO, VJ;
Pol yani l i ne-support ed sul f uri c aci d sal t as a powerf ul
cat alyst for t he prot ect ion and deprot ect ion of carbonyl
compounds
Synlet t (2003) (12) : 1793-1796
PARTHASARATHY, G;CHOUDARY, BM;SREEDHAR,
B;KUNWAR, AC; SRINIVASAN, R; Ferrous saponit e from
t he Deccan Trap, India, and it s applicat ion in Adsorpt ion
and reduct ion of hexavalent chromium
American Mineralogist (2003) 88(11-12 Part 2):1983-1988
PARTHASARATHY, G;VAIRAMANI, M; Test in for fullernes
i n geol ogi c mat eri al s: Okl o carbonaceous subst ances,
Karel i an shungi t es, Sudbury Bl ack Tuf f : Comment and
Repl y
Geology (2003) : e32-e33
PRASAD, TEV;KUMAR, SS;GOUD, MBP;KUMAR,
PA;SRINIVAS, A;REDDY, PS;PRASAD, DHL; Bu b b l e
t emperat ure measurement s on binary mixt ures formed
by cyclohexane at 94.7 kPa
Journal of Chemical and Engineering Data (2003) 48(2)
: 351-353
PRASAD, TEV; KUMAR, BS; NAVEEN, PG;PRASAD, VVJ;
PRASAD, DHL; Boi l i ng t emperat ure measurement s on
t he bi nary mi xt ures of n-hexane wi t h Some al i phat i c
al cohol s
Physics And Chemist ry Of Liquids (2003) 41(1) : 39-43
PRASAD, TEV;RAMSERISH, GV;SATYAKISHORE, P;PRASAD,
DHL; Boiling Point Temperat ures of t he Binary Mixt ures
of 1,3-Dimet hylbenzene Wit h Met hanol, 1-Propanol or
2-Propanol at 95 kPa
Chemical Engineering Communicat ions (2003) 190 :
171-176
NARENDER, N;MOHAN, KKVV;REDDY, RV;SRINIVASU,
P;KULKARNI, SJ; RAGHAVAN, KVLi q u i d p h ase
brominat ion of phenols using pot assium bromide and
hydrogen Peroxide over zeolit es
192(1-2) : 73-77
NARENDER, N;MOHAN,KVVK;KULKARNI, SJ;RAGHAVAN,
KV; Mi l d and regi osel ect i ve oxi dat i ve bromi nat i on of
aromat i c compounds usi ng ammoni um bromi de and
oxone
Journal of Chemical Research Part S (2003) (9) : 597-
598
NARSAIAH,AV;NAGAIAH, K; Ant i mony p ent achl or i de-
promot ed regenerat i on of carbonyl compounds f rom
oximes
NARSAIAH, AV;NAGAIAH, K; Lan t h an u m ch l o r i d e
medi at ed-regenerat i on of carbonyl compounds f rom
oximes in wat er - Indian Journal of Chemist ry Sect ion B
Organic Chemist ry I ncludingMedicinal Chemist ry
(2003) 42(9) : 2045-2047
NARSAIAH, AV;NAGAIAH, K; An ef f i ci ent Knoevenagel
condensat ion cat alyzed by LaCl3 cent er dot 7H(2)O in
het erogeneous medi um
NISHA, CK;BASAK, P;MANORAMA, SV;MAITI, S; JAYA
CHANDRAN, KN; Wat er-soluble complexes from random
co p o l ymer an d o p p o si t el y ch ar g ed Su r f act an t . 1.
Comp l exes of p ol y(et hyl ene g l ycol )-b ased cat i oni c
random Copol ymer and sodi um dodecyl sul f at e
Langmuir (2003) 19(7) : 2947-2955
NOORJAHAN, M;REDDY, MP;KUMARI, VD;LAVDRINE,
B;BOULE; P;SUBRAHMANYAM, M Ph o t o cat al yt i c
degradat ion of H-acid over a novel TiO
2
t hin film fixed
bed React or and in aqueous suspensions
Journal of Phot ochemi st ry and Phot obi ol ogy A:
Chemist ry (2003) 156(1-3) : 179-187
157
PRASAD, TEV;SANKAR, B;KUMAR PAVAN;PRASAD, DHL;
Boi l i ng t emp er at ur e measur ement s on t he b i nar y
mixt ures formed by t ert -but anol wit h some chloret ha
nes and chloroet hylenes at 94.6 kPa
Fluid Phase Equilibria (2003) 213(1-2) : 147-152
PRIYAKUMAR, UD;SASTRY, GN; Measur es t o eval uat e
h et er o ar o mat i ci t y an d t h ei r l i mi t at i o n s: St o r y o f
skel et al l y Subst i t ut ed benzenes - Proceedi ngs Of The
Indian Academy of Sciences
Chemical Sciences (2003) 115(1) : 49-66
PRIYAKUMAR, UD;SASTRY, GN; Cat i on-i nt eract i ons of
cu r ved p o l ycycl i c syst ems: M+ (M= Li an d Na) i o n
Complexat ion wit h buckybow
RADHAKRISHNA, P;KANNAN, V;SHARMA, GVM;RAO,
MHVR; Di ast ereosel ect i ve Bayl i s-Hi l l man react i on: Use
of sugar derived aldehydes as Chiral elect rophiles
Synlet t (2003) (6) : 888-889
RADHAKRISHNA, P;LAVANYA, B;SHARMA, GVM; St ereo
sel ect i ve synt hesi s of C-phenyl - and -gl ycero hept o
pyranosi des
RADHAKRISHNA, P;EMPATI RAJA SEKHAR;KANNAN, K;
The use of acet yl eni c al d ehyd es i n Bayl i sHi l l man
react ions: synt hesis of Versat ile allyl propargyl alcohols
RADHAKRISHNA, P;REDDY, VVR;SHARMA, GVM; A
versat i l e prot ocol f or t he synt hesi s of oxazol e and 3-
nit ro/ 3-carbet hoxy pyrrole C-nucleosides using TOSMIC
Synlet t (2003) (11) : 1619-1622
RADHAKRISHNA, P;LAVANYA, B;JYOTHI, Y;SHARMA, GVM;
Rad i cal - med i at ed d i ast er eo sel ect i ve syn t h esi s o f
benzot hiazole sulfonyl Et hyl C-glycosides
Journal of Carbohydrate Chemistry (2003) 22(6) : 423-
431
RAGHAVAN, SADAGOPAN;ANURADHA, K; Sol i d-phase
synt hesi s of het erocycl es from 1,4-di ket one synt hons
Synlet t (2003) (5) : 711-713
RAGHAVAN, SADAGOPAN;JOSEPH, SC; Th e su l f i n yl
mo i et y as an i n t r amo l ecu l ar n u cl eo p h i l e. Par t 3:
Synt hesis of (-)
Muricat acin Tet rahedron: Asymmet ry (2003) 14(1) :
101-105
RAGHAVAN, SADAGOPAN;JOSEPH, SC; Th e su l f i n yl
moi et y as an i nt er nal nucl eop hi l e. Par t 8: Ef f i ci ent ,
st ereospecific Synt hesis of (+)-polyoxamic acid
RAGHAVAN, SADAGOPAN;JOSEPH, SC; A n ovel an d
st ereospecific synt hesis of (+)-exo-brevicomin
RAGHAVAN, SADAGOPAN;RAJENDER, A; Novel , shor t ,
st er eo sel ect i ve syn t h esi s o f l yxo - (2R,3R,4R)-
phyt osphi ngosi ne and Eryt hro-(2R,3S)- Sphi ngosi ne
7097
RAGHAVAN, SADAGOPAN;RAJENDER, A; RASHEED,
M ABDUL;REDDY, SR; Synt hesis of t et rahydrofurans via
silicon promot ed Pummerer t ype react ion
RAGHAVAN, SADAGOPAN;RAJENDER, A;YADAV,
JS; Novel, efficient and st ereospecific synt hesis of xylo-
(2R,3S,4S)- p h yt o sp i n g o si n e An d Th r eo - (2R- 3R)-
sphi ngosi ne
RAGHAVAN, SADAGOPAN;RASHEED, M ABDUL; Sul fi nyl
moiet y as an int ernal nucleophile. Part 6: St ereospecific
synt hesi s of 3-ami no-2-hydroxy-4-phenyl but anoat e -
Trahedron Asymmet ry (2003) 14(10) : 1371-1374
Publications
158
RAMANA, GV;RAO, BV; St ereoselect ive synt hesis of (-)-
and (+)-pent enomycins using RCM
RAMESH, CHIMMANI;BANERJEE, J;PAL, R;DAS, B; St udies
o n n o vel syn t h et i c met h o d o l o g i es, Par t 25- Si l i ca
sup p or t ed sodi um Hydr ogen Sul f at e and amer l yst -
15:Two ef f i ci en t h et er og en ou s cat al yst s f or f aci l e
synt hesi s of bi s-and t ri s(1H-i ndol -3-yl )met hanes f rom
indoles and carbonyl compounds
Advanced Synthesis and Catalysis (2003) 345(5) : 557-559
RAMESH, CHIMMANI;MAHENDER, G;RAVINDRANATH,
N;DAS, B; A mild, highly select ive and remarkably easy
procedure for deprot ect ion of Aromat ic acet at es using
ammoni um acet at e as a neut ral cat al yst i n aqueous
Medium
Tet rahedron (2003) 59(7) : 1049-1054
NASI;DAS, B; A simple, mild and efficient procedure for
sel ect i ve cl eavag e o f p r en yl est er s Usi n g si l i ca-
su p p o r t ed so d i u m h yd r o g en su l p h at e as a
het erogenous cat al yst
NASI;DAS, B; A convenient , rapid, highly select ive and
eco-f ri endl y met hod f or deprot ect i on of aryl acet at es
Usi ng si l i ca gel support ed ammoni um f ormat e under
mi crowave i rradi at i on
Green Chemist ry (2003) 5(1) : 68-70
RAMESH, CHIMMANI; RAVINDRANATH, NASI; DAS,
B; El ect rophi l i c subst i t ut i on react i ons of i ndol es wi t h
carbonyl compounds using ceric ammonium nit rat e: A
novel and efficient met hod for t he synt hesis of di-and
t ri -i ndol yl met hanes
Journal of Chemical Research-S (2003) (2) : 72-74
RAMESH, CHIMMANI; RAVINDRANATH, NASI; DAS,
B; Simple, efficient and select ive deprot ect ion of phenolic
met hoxymet hyl et hers usi ng si l i ca-Support ed sodi um
hydrogen sul f at e as a het erogenours cat al yst (1)
7103
RAGHAVAN, SADAGOPAN;RASHEED, M ABDUL; A novel
and st ereospecific synt hesis of (+)-preussin
Tet rahedron (2003) 59(51) : 10307-10312
RAGHAVAN, SADAGOPAN;REDDY, SR; The sulfinyl Moiet y
as an i nt ernal nucl eophi l e 2.St ereosel ect i ve synt hesi s
of (-)-Galant inic Acid via 1,3-asymmet ric induct ion
The Journal of Organic Chemist ry (2003) 68(14) :
5754-5757
RAGHAVAN, SADAGOPAN;REDDY, S RAMAKRISHNA;
Pract i cal , effi ci ent , st ereosel ect i ve, formal synt hesi s of
(2R,3R,4R) 3-hydroxy-4-Met hyl prol i ne
RAGHAVAN, SADAGOPAN;TONY, KA; Sul f i nyl moi et y as
an i nt er nal nucl eop hi l e. 1. Ef f i ci ent st er eosel ect i ve
synt hesis of fragment a of crypt ophycin 3
5005
RAGHUNATH, P;SITHA, S;BHANUPRAKASH, K;CHOUDARY,
BM; Format ion of t he silicon analogues of isocyanic acid,
HNSiO, and it s isomers by Neut ral-neut ral react ions of
t he fragment s: A comput at ional st udy
Journal of Physi cal Chemi st ry A (2003) 107(51) :
11497-11504
RAHMAN, MF;SIDDIQUI, MKJ; Bi och emi cal en zyme
act i vi t y i n di fferent t i ssues of rat s exposed t o o Novel
phosphorot hinoat e - Journal of Environment al Science
Healt h Part B
Pest icides, Food Cont aminant s and Agricult ure Waste
(2003) 38(1) : 59-71
RAJGOPAL, K;KRISHNA KUMAR, RV;NANDHINI,
MS;RAVIKUMAR, K; NATRAJAN, S; Bi s (DL- al an i n e)
t et raaquacobal t (l l ) di ni t rat e
Act a Cryst allographica , Sect ion C (2003) 59(Part -8)
: M562-M564
RAM, SR;CHARY, KP;SALAHUDDIN, S;IYENGAR, DS; An
ef f i ci ent chemosel ect i ve product i on of ami nes f rom
azides using AlCl
3
/ NaBH
4
I ndi an Jour nal of Chemi st r y Sect i on- B Or gani c
Chemistry Including Medicinal Chemistry (2003) 42(4)
: 935-937
159
RAMESH, CHIMMANI; RAVINDRANATH, NASI;DAS,
B;PRABHAKAR, A; BHARATAM, J; RAVIKUMAR,
K; KASHINATHAM, A;McMORRIS, TC; Pseudoguainolides
from t he flowers of Part henium hyst erophorus
Phyt ochemist ry (2003) 64(4) : 841-844
RAMESH, CHIMMANI; RAVINDRANATH, NASI; RAM,
TEJOMOORTULA SIVA; DAS, B; Arylnapht halide Lignans
from Cleist ant hus collinus
Chemical & Pharmaceut ical Bullet in (2003) 51(11) :
1299-1300
RANGANATHAN, S;KUNDU, D;VUDAYAGIRI, SD; Prot ei n
evo l u t i o n - i n t r i n si c p r ef er en ces i n p ep t i d e- b o n d
format ion-A comput at ional and experiment al-analysis
Journal of Biosciences (2003) 28(6) : 683-690
RAO, AG;PRASAD, K KRISHNA;NAIDU, GV;RAO,
CHANDRASHEKAR N; SARMA, PN; Removal of sulfide in
i nt egrat ed anaerobi c-aerobi c wast ewat er t reat ment
syst em
Clean Technological Environment al Policy (2003) (6) :
66-71
RAO, AG;ANNAPURNA, JETTY; Pur i f yi ng wast e gas i n
pharmaceut i cal i ndust ry
Pharma Bio World (2003) Feb-Apr : 84-89
RAO, AG;ANNAPURNA, JETTY; Biofilt ers promise bet t er
odour removal i n pharma i ndust ry
Pharma Bio World (2003) May-Jul : 87-91
RAO, AG;ANNAPURNA, JETTY; Bi o t ech n o l o g i cal
processes for hydrogen sulfide removal from gaseous
st reams
Pharma Bio Wold (2003) Aug-Oct : 141-144
RAO, JL;BHANUPRAKASH, K; Comput at ional st udies of
t h e n o n - l i n ear o p t i cal p r o p er t i es o f so me t h r ee-
Di mensi onal mol ecul es: ef f ect of t hr ough b ond
int eract ion on t he first Hyperpolarizabilit y
Synt het ic Met als (2003) 132(3) : 315-324
RAO, JV;KAVITHA, P;RAO, AP; Comparat i ve t oxi ci t y of
t et ra et hyl lead and lead oxide t o eart hworms, Eisenia
fet i da (Savi gny)
Environment al Research (2003) 92(3) : 271-276
RAO, JV;KAVITHA, P;MAKKAPATI, AK; Ef f i cacy o f
i mi d acl o p r i d g el (MAXFORCE ) b ai t t o co n t r o l
cockroach infest at ion in food st orage godowns
Pest ology (2003) XXVII (2) : 7-12
RAO, JV;PAVAN, YS;MADHAVENDRA, SS; Toxi c effect s of
chl orpyri f os on morphol ogy and acet yl chol i nest erase
act ivit y in t he eart hworm, Eisenia foet ida
Ecot oxi col ogy and Envi ronment al Saf et y (2003)
54(3) : 296-301
RAO, JV;RANI, CHS;KAVITHA, P;RAO, RN;MADHAVENDRA,
SS; Toxi ci t y of Chl or p yr i f os t o t he f i sh Oreochr omi s
mossambi cus
Bul l et i n of Envi r onment al Cont ami nat i on &
Toxicology (2003) 70(5) : 985-992
RAO, JV; SHILPANJALI, D;KAVITHA, P;MADHAVENDRA,
SS; Toxi c ef fect s of prof enofos on t i ssue acet yl chol i ne
st er ase an d g i l l mo r p h o l o g y i n a Eu r yh al i n e f i sh ,
Oreochromi s mossambi cus
Archives Of Toxicology (2003) 77(4) : 227-232
RAO, KN;LINGAIAH, N;SURYANARAYANA, I;PRASAD, PSS;
A compari son of st ruct ure and cat al yt i c f unct i onal i t y
of 12-molybdophosphoric Acid and it s ammonium salt
i n t h e ammo xi d at i o n o f 2- met h yl p yr azi n e t o 2-
cyanopyrazi ne
RAO, K VENKATA SUBBA;RACHEL, A;SUBRAHMANYAM,
M;BOULE, P; Immobi l i zat i on of Ti O2 on pumi ce st one
f or t he phot ocat al yt i c degradat i on Of dyes and dye
i ndust ry pol l ut ant s
77-85
Publications
160
RAO, RN;RAJU, DN;VENKATESWARLU, N;RAO, BV;
PARVATHI, N;MANJULA, A;REDDY, GN;GAWALI, PB;
SREEKANTH, M; RAO, PN; Development and validat ion
of a liquid chromat ographic met hod for monit oring of
p r o cess- r el at ed syn t h esi s o r g an i c i mp u r i t i es o f
profenofos in t echnical product s
Journal of Chromat ographic Science (2003) 41(8) :
418-421
RAO, RN;VENKATESWARLU, N; KHALID, S;NARASIMHA, R;
Liquid chromat ographic separat ion and det erminat ion
of aromat ic Sulfonat es in an aquat ic environment using
a phot odi ode array and El ect rospray i oni zat i on-mass
spect romet er as det ect ors Analyt ical Sciences
The Int ernat ional Journal Of The Japan Societ y For
Analyt ical Chemist ry (2003) 19(4) : 611-615
RAO, RN;VENKATESWARLU,N;RAO, BV;RAJU, PVC;
KRISHNAIAH, A; Separat ion and det erminat ion of small
amount s of sul f ur i n t echni cal Thi opharat e-met hyl by
r ever sed -p hase hi gh-p er f or mance l i q ui d chr omat o
graphy
Journal of Separat ion Science (2003) 26(9-10) : 932-
934
RAO, VVVNSR;RAVIKANTH, S;REDDY, GV;MAITRAIE,
D;YADLA, R;RAO, PS; Microwave assist ed int ramolecular
Wi t t i ng react i on: A f aci l e met hod f or t he synt hesi s of
conj ugat ed acet yl enes
RAO, SHAILAJA, K;ACHAR, PN;RAHMAN, MF; Biochemical
changes i nduced i n Li ver and Serum of Di pl odi at oxi n
(St enocarpella maydis) Treat ed Male and Female Rat s
Drug and Chemical Toxicology (2003) 26(4) : 231-243
RATHNA; GVN;CHATTERJI, PR; Cont rol l ed drug rel ease
f r om g el at i n-sod i um car b oxymet hyl cel l ul ose Int er
p en et r at i n g p ol ymer n et w or ks - Jour n al of Macr o
molecular Science
Pure & Applied Chemist ry A40(6) : 629-639
RAO, K VENKATA SUBBA;KANDAVELU, V;SRINIVAS, B;SUBRAH
MANYAM, M;THAMPI, KR; A novel rout e for t he synt hesis of
piperazine from N-(2,3-dihydroxy propyl) et hylenediamine over
composit e phot ocat alyst s
RAO, K VENKATA SUBBA;SRINIVAS, B;SUBRAHMANYAM, M; Titanium
oxide loaded zeolit es as phot ocat alyst s for t he cyclizat ion of
Et hylenediamine wit h propylene glycol
RAO, K VENKATA SUBBA;SUBRAHMANYAM, M; BOULE, P;
Phot ocat alyt ic t ransformat ion of dyes and by-product s
in t he presence of hydrogen-Peroxide
Environment al Technology (2003) 24(8) : 1025-1030
RAO, MHV RAMANA;KUMAR, S KIRAN;KUNWAR, AC;
Format ion of b- hairpins in L-Pro-Gly cont aining pept ides
facilit at ed by 3-amine Benzoic acid
Tetrahedron Letters (2003) 44(39) : 7369-7372
RAO, PK;RAO, KSR;PADMASRI, AH; Transf ormat i on of
chl orof l uorocarbons t hrough cat al yt i c Hydrodehal o
genat i on
Cat t ech (2003) 7(6) : 218-225
RAO, PR;REDDY, MN;RAMAKRISHNA, S;DIWAN, PV;
Co mp ar at i ve i n vi vo eval u at i o n o f p r o p r an o l o l
h yd r o ch l o r i d e af t er o r al An d t r an sd er mal ad mi n i
st rat i on i n rabbi t s
Eur opean Jour nal of Phar maceut i cs and
Biopharmaceut ics (2003) 56(1) : 81-85
RAO, R JAGADEESHWAR;TIWARI, ASHOK K; KUMAR, U
SAMPATH; REDDY, S VENKAT;ALI, AMTUL Z;RAO, J
MADHUSUDANANovel 3-O-acyl mesqui t ol anal ogues as
f r ee- Rad i cal scaven g er s an d en zyme i n h i b i t o r s:
synt hesi s, b i ol ogi cal eval uat i on and st r uct ur e-act i vi t y
r el at i on sh i p
13(16) : 2777-2780
RAO, RN;NAGARAJU, V; A over view of t he recent t rends
in development of HPLC met hods for det erminat ion of
impurit ies in drugs
Journal of Pharmaceut ical and Biomedical Analysis
(2003) 33(3) : 335-377
161
RAVIKANTH, V;REDDY, VLN;RAMESH, P;RAO, TP;DIWAN,
PV;KHAR, A;VENKATESWARLU, Y; Cor ri gendum t o An
immunosuppressive t rypt ophan-derived alkaloid from
Lepidagat his crist at a [Phyt o chemist ry 58 (2001) 1263
1266]
Phyt ochemist ry (2003) 62(2) : 243
RAVIKANTH, V; REDDY, VLN; REDDY, AV; DIWAN,
PV; VENKATESWARLU, Y; Di t erpenes from t he lat ex of
Euphorbia nivulia,
447-449
RAVIKANTH, V;REDDY, VLNR;REDDY, AV;KODELA,
R;TADIKAMALLA, VR;TEJOMOORTY, SR;KONDAPI,
AK;DIWAN, PV;VENKATESWARLU, Y; Three New Ingol
Di t er p en es f r o m Eu p h o r b i a n i vu l i a: Eval u at i o n o f
Cyt ot oxi c Act i vi t y
431-434
RAVINDRANATH, NASI;RAMESH, C;DAS,B; A r ar e
di nordi t erpene from Jat ropha curcas
431-432
RAVINDRANATH, NASI;RAMESH, C;KISHORE, KH;MURTY,
USN;DAS B; Cl er od end r one, a novel hyd r oq ui none
dit erpenoid from Clerodendrum indicum
Journal of Chemical Research-S (2003) (7) : 440-441
RAVINDRANATH, NASI;RAMESH, C;REDDY, MR;DAS, B; A
f aci l e an d con ven i en t t h r ee-comp on en t cou p l i n g
prot ocol for t he synt hesis of Pyrano and furoquinolines
RAVINDRANATH, NASI;VENKATAIAH, B;RAMESH,
C;JAYAPRAKASH, P;DAS, B; Jat r o p h en o n e, a Novel
Macr o cycl i c Bi o act i ve Di t er p en e f r o m Jat r o p h a
gossypi f ol i a
870-871
RAVINDRANATH, NASI;RAMESH, C;REDDY, MR;DAS, B;
Sel ect i ve r emoval of n-b oc p r ot ect i ng g r oup f r om
aromat i c ami nes usi ng Si l i ca gel -support ed sodi um
hyd r ogen sul f at e and HY-zeol i t e a het er ogeneous
cat al yst s
Advanced Synt hesis & Cat alysis (2003) 345(11):1207-
1208
RAVINDRANATH, NASI;RAMESH, C;REDDY, MR;SRINIVAS,
KVNS;DAS, B; Acet yl at i on of camp t ot h eci n s u si n g
lit hium bromide as cat alyst
RAVIPRASAD, P;BHUVANESWARI, K;SASTRY, GSR;
Sp ect r op hot omet r i c d et er mi nat i on of ker osone i n
ground wat ers
Indian Journal of Environment al Prot ect ion (2003)
23(9) : 964-965
RAVIPRASAD, P;SASTRY, GSR;SARMA, PN;St udies on t he
charact eri zat i on and ut i l i zat i on of sol i d wast e f rom a
bat t ery Manuf act uri ng i ndust ry
Pollut ion Research (2003) 22(1) : 73-75
REDDY, AV;RAVINDER, K;REDDY, VLN;GOUD,
TV; RAVIKANTH, V; VENKATESWARLU, Y; Zeo l i t e
cat alyzed synt hesis of bis(indolyl) met hanes
Synt het i c Communi cat i ons (2003) 33(21) : 3687-
36942
REDDY, AV;RAVINDER, K;REDDY, VLN;RAVIKANTH, V;
VENKATESWARLU, Y; Amber l yst -15cat al yzed ef f i ci ent
synt hesis of 1,1-diacet at es from aldehydes
REDDY, AV;RAVINDER, K;GOUD, TV;KRISHNAIAH, P;RAJU,
TV; VENKATESWARLU, Y; Bi smut h t r i f l at e cat al yzed
conj ugat e addit ion of indoles t o-enones
REDDY, BM;GANESH, I;KHAN, A; Pr ep ar at i o n an d
charact eri zat i on of In2O3-Ti O2 and V2O5/ In2O3-Ti O2
Composit e oxides for cat alyt ic applicat ions
Applied Catalysis A: General (2003) 248(1-2) : 169-180
Publications
162
REDDY, GV;RAO, VVVNS RAMA;MAITRAIE, D;RAVIKANTH,
S;YADLA, R; REDDY, SN;NARSAIAH, B;RAO, P SHANTHAN
St ud i es on t he r eact i on of unsymmet r i cal t r i f l uor o
met hyl 1,2-phenyl enedi ami ne wi t h vari ous ket ones
leading t o novel fluorinat ed het erocycles
Journal of Fluorine Chemist ry (2003) 124(2) : 203-209
REDDY, KM;MANORAMA, SV;REDDY, AR; Ban d g ap
st udies on anat ase t it anium dioxide nanopart icles
Materials Chemistry and Physics (2003) 78(1) : 239-245
REDDY, KR;RAMESH, K; SEELA, KK; RAO, VV; CHARY, KVR
Alkylat ion of phenol wit h met hanol over molybdenum
oxide support ed on NaY zeolit e
REDDY, KR;REDDY, CV;MAHESH, M;RAJU, PVK; REDDY, VV
NARAYANA; New environment ally friendly solvent free
synt hesi s of di hydrop yri mi di nones Cat al ysed b y N-
but yl -N,N-di met hyl -phenyl et hyl ammoni um bromi de
REDDY, KR;BHASKAR, T;CHARY, KVR; St r u ct u r e an d
react i vi t y of mol ybdenum oxi de cat al yst s support ed
on LA203 St abilized t et ragonal ZrO2
Langmuir (2003) 19(26) : 10795-10802
REDDY, M ARJUN;SURENDRA, K;BHANUMATHI, N; RAO,
KR; Co r r i g en d u m t o Hi g h l y f aci l e b i o mi met i c
regioselect ive ring opening of epoxides t o halohydrins
in t he presence of
cycl odext r i n: [ Tet r ahedr on 5 8 ( 2 0 0 2 ) 6 0 0 3 ]
Tet rahedron (2003) 59(13) : 2363
REDDY, MK; REDDY, MVB; GUNASEKAR, D; MURTHY, MM;
CAUX, C;BODO, B; A flavone and an unusual 23-carbon
t erpenoi d f rom Andrographi s pani cul at a
Phyt ochemist ry (2003) 62(8) : 1271-1275
REDDY, MVB;REDDY, MK;GUNASEKAR, D;MURTHY,
MM;CAUX, C;BODO, B; A new sesqui t erpene l act one
from Bombax-Mal abari cum
458-459
REDDY, BM;KHAN, A;YAMADA, Y;KOBAYASHI, T; LORIDANT,
S;VOLTA, JC; Raman an d X- r ay p h o t o el ect r on
spect roscopy st udy of CeO2-ZrO2 and V2O5/ CeO2-ZrO2
cat al yst s
Langmuir (2003) 19(7) : 3025-3030
REDDY, BM;KHAN, A;YAMADA, Y;KOBAYASHI, T;
LORIDANT, S;VOLTA, JC; St ruct ural Charact eri zat i on of
CeO2-Ti O2 and V2O5/ CeO2-Ti O2 Cat al yst s by Raman
and XPSTechniques
Journal of Physical Chemisty B (2003) 107(22) : 5162-
5167
REDDY, BM;SREEKANTH, PM; An efficient synt hesis of 1,5-
b en zo d i azep i n e d er i vat i ves cat al yzed b y a so l i d
Superacid sulfat ed zirconia
REDDY, BM;KHAN, A;YAMADA, Y;KOBAYASHI, T; St ruct ural
charact erizat ion of CeO2-MO2 (M = Si4+, Ti4+, and Zr4+)
mi xed oxi d es by Raman sp ect r oscop y, X-r ay p hot o
elect ron spect roscopy, and ot her t echniques
Journal of Physi cal Chemi st ry B (2003) 107 (41):
11475-11484
REDDY, CS;SMITHA, G;CHANDRASEKHAR, S; ZrCl 4 as a
mi l d and effi ci ent cat al yst for t he one-pot conversi on
of TBS and THP et hers t o acet at es
REDDY, GSN;PRAKASH, JSS;SRINIVAS, R;MATSUMOTO,
GI;SHIVAJI, S; Leifsonia-Rubra Sp-Nov and Leifsonia-Aurea
Sp-Nov. Psychrophiles from a pond In Ant arct ica
Int ernat ional Journal of Syst emat ic and Evolut ionary
Microbiology (2003) 53(JUL) : 977-984
REDDY, GV;BABU, PR;KOMARAIAH, P;ROY, KRRM;
KOTHARI, IL Ut i l i zat i o n o f b an an a w ast e f o r t h e
product i on of l i gnol yt i c and cel l ul ol yt i c enzymes by
so l i d su b st r at e f er men t at i o n u si n g t w o Pl eu r o t u s
species (P. ost reat us and P. saj or-caj u)
Process Biochemist ry (2003) 38(10) : 1457-1462
163
REDDY, NK;RAO, KS;MULAY, VN; Magnet i c behavi or of
La(0.5)Ka(0.5)Me(2)Fe(16)O(27) hexagonal ferrit es
Journal of Mat erials Science Let t ers (2003) 22(22) :
1563-1565
REDDY, SV;RAO, RJ;KUMAR, US;RAO, JM; Highly efficient
and convenient deprot ect ion of met hoxymet hyl et hers
and est ers using bismut h t riflat e in an aqueous medium
REDDY, TJ;MIRZA, SP;SARADHI, UVRV;RAO, VJ;
VAIRAMANI, M; Mass sp ect r al st u d i es o f N,N-
di al kyl ami noet hanol s
Rapid Communicat ions in Mass Spect romet ry (2003)
17(7) : 746-752
REDDY, VL NIRANJAN;RAVINDER, KODELA;SRINIVASULU,
MASUNA; GOUD, T VENKATESHWAR;REDDY, SM; SRUJAN
KUMAR, D;RAO, T PRABHAKAR;MURTY, U SURYA
NARAYANA; VENKATESWARLU, Y; Two new macrocyclic
diaryl et her hept anoids from Boswellia ovalifoliolat a
1081-1084
REDDY, VL NIRANJAN;RAVIKANTH, V;JHANSILAKSHMI,
VVNS;MURTY, U SURYANARAYANA;VENKATESWARLU, Y;
In h i b i t o r y act i vi t y o f h o mo i so f l avo n o i d s f r o m
Caesal pi ni a Sappan agai nst Beauveri a Bassi ana
Fit ot erapia (2003) 74(6) : 600-602
SABITHA, G;REDDY, GS KIRAN KUMAR; REDDY, Ch
SRINIVAS;YADAV, JS; A novel TMSI-medi at ed synt hesi s
o f Han t zsch 1,4- d i h yd r o p yr i d i n es at amb i en t
Temperat ure
SABITHA, G;REDDY, Ch SRINIVAS;REDDY, ChMEV;YADAV,
JS; Bi Cl 3-cat al yzed di ast ereosel ect i ve i nt ramol ecul ar
[ 4,2] cycl oad d i t i on React i ons l ead i ng t o p yr azone
annulat ed new sulfur het erocycles
SABITHA, G;REDDY, GS KIRANKUMAR;REDDY, Ch
SRINIVAS;YADAV, JS; On e- p o t syn t h esi s o f
dihydropyrimidinones using iodot rimet hylsilane. Facile
and new improved prot ocol for t he Biginelli react ion at
room t emperat ure
Synlet t (2003) (6) : 858-860
SABITHA, G;REDDY, GSKIRANKUMAR;REDDY, Ch
SRINIVAS;FATIMA, N; YADAV, JS; Zr(NO3)(4) : A versat i l e
oxi d i zi ng agent f or ar omat i zat i on of Hant zsch 1,4-
di hydropyri di nes and 1,3,5-t ri subst i t ut ed pyrazol i nes
SABITHA, G;REDDY, GS KIRANKUMAR, RAJKUMAR,
M;YADAV, JS; RAMAKRISHNA, KVS;KUNWAR, AC;
Io d o t r i met h yl si l an e i n d u ced d i ast er eo sel ect i ve
syn t h esi s o f t et r ah yd r o p yr an o n es b y a t an d em
knoevenagel Michael react ion
SABITHA, G;REDDY, GSKK;REDDY, KB;YADAV, JS;
Vanadi um(III) chl ori de-cat al yzed preparat i on of bet a-
amino alcohols from epoxides
SABITHA, G;REDDY, GS KIRANKUMAR;REDDY, K
BHASKAR; YADAV, JS; Vanadi um (III) chl ori de cat al yzed
Bi g i n el l i co n d en sat i o n : so l u t i o n p h ase l i b er al
Generat i on of di hydropyri mi di n-(2H)-ones
SABITHA, G;REDDY, CS;SRIHARI, P;YADAV, JS; St er eo
select ive t ot al synt hesis of (+)-virol C
SAIESWARI, A;PRIYAKUMAR, UD;SASTRY, G NARAHARI;
On t he use of NICS crit erion t o evaluat e aromat icit y in
het eroaramat i cs i nvol vi ng III and IV row mai n group
el ement s
663(1-3) : 145-148
SAIRAM, M;PALANIAPPAN, S; Benzoyl peroxide oxidat ion
rout e t o pol yani l i ne sal t and i t s use as cat al yst i n t he
Est eri fi cat i on react i on
201(1-2) : 289-296
SAIRAM, M;SREEDHAR, B;RAO, DVM;PALANIAPPAN, S;
Synt hesis and t hermal degradat ion kinet ics of cellulose
est ers
477-485
Publications
164
SESHADRI, PR;SELVANAYAGAM, S;VELMURUGAN,
D;RAVIKUMAR, K; SURESHBABU, AR;RAGHUNATHAN, R;
2 -Benzoyl-1 ,2,2 ,3,4 ,5 ,6 ,6a -oct ahydro-1H-indan-2-
spi ro-3 -(3 H-pyrrol i zi ne)-1 -spi ro-3 -1H-i ndol i ne-1,2
,3-t r i one
Online) (2003) 59(Part 10) : O1559-O1561
D;RAVIKUMAR, K SURESHBABU, AR;RAGHUNATHAN, R;
2 -(p-Met hoxybenzoyl)-1 ,2,2 ,3,5 ,6 ,7 ,7a -oct ahydro-
1H-i ndan-2-spi ro-3 -(3 H-pyr rol i zi ne)-1 -spi ro-3-1H-
indoline-1,2 ,3-t rione
Online) (2003) 59(Part 11) : O1783-O1785
1-Met hyl -4 -(3-ni t r op heny1)-1H-i nd ol e-3-sp i r o-2 -
pyrrolidine-3 -spiro-2 -indan-2,1 ,3 t rione
Online) (2003) 59(Part 12):O2025-O2027
SHARMA, GVM;BEGUM, ASRA;REDDY, K RAVINDER;
SANKAR, A RAVI; KUNWAR, AC; Hi ghl y st ereosel ect i ve
synt hesi s of f urano-oxepanes: i nt ramol ecul ar ni t rone
cycl oad d i t i on (INC) r eact i on s on su g ar d er i ved 2-
subst it ut ed allylic et hers
SHARMA, GVM;CHANDRA MOULI, Ch; A t ot al synt hesis
of macrosphelides C and F from (+)-arabinose
SHARMA, GVM;GOPINATH, T; Rad i cal cycl i sat i o n
ap p r oach f or t he synt hesi s of (+ ) d i hyd r o canad en
solide,(+) Dihydrosporot hriolide and t heir C-3 epimers
from xyl ose
Tet rahedron (2003) 59(34) : 6521-6530
SAMPATH KUMAR, U;APARNA, P;RAO, RJ;RAO, TP;RAO,
JM; 1-Met hyl ant hr aq ui nones and t hei r b i ogenet i c
p r ecu r so r s f r o m st er eo p er mo n e p er so n at u m
Phyt ochemist ry (2003) 63(8) : 925-929
SAMPATH KUMAR, U;APARNA, P;RAO, R JAGADEESHWAR;
RAO, T PRABHAKAR;RAO, J MADHUSUDANA Errat um t o
1- Met h yl an t h r aq u i n o n es an d t h ei r b i o g en et i c
precursors f rom St ereospermum personat um
Phyt ochemist ry (2003) 64(4) : 907
SASTRY, G MADHAVI; Applicat ion of N-part icle random
walk t o geminat e recombinat ion of a hemeprot ein Wit h
a ligand
Chemical Physical Let t ers (2003) 379(5-6) : 547-554
SASTRY, G NARAHARI; Organi c chemi st s conquer t he
synt hesis of C-60
Current Science (2003) 85(2) : 125-126
SATYANARAYANA, L;REDDY, KM;MANORAMA, SV;
Syn t h esi s o f n an o cr yst al l i n e Ni
1-x
Co
x
Mn
x
Fe
2-x
O
4
: a
mat erial for liquefied Pet roleum gas sensing
Sensors and Act uat ors B : Chemical (2003) 89(1-2) :
62-67
SATYANARAYANA, L;REDDY, KM;MANORAMA, SV;
Nanosi zed spi nel Ni Fe2O4: A novel mat eri al f or t he
det ect ion of liquefied pet roleum gas in air mat erials
Chemist ry and Physics (2003) 82(1) : 21-26
SATYAVATHI, B;PATWARI, AN;RAO, M BHAGWANTH;
Reg i o-sel ect i ve cat al yt i c vap or p hase al kyl at i on of
aniline: Preparat ion of 2,6-diet hylaniline
Spi r o-[ 2-3] oxi ndol e-spi ro-[ 3-3] oxi ndol e-4[ p-met hyl
benzyl ]pyrrol i di zi ne
Online) (2003) 59 (Part 10) : O1458-O1460
165
SHARMA, GVM;ILANGOVAN, A;NARAYANAN, VL;GURJAR,
MK; Fi rst synt hesi s of aza-cal anol i des- a new cl ass of
ant i-HIV act ive compounds
Tet rahedron (2003) 59(1) : 95-99
SHARMA, GVM;RAKESH;SUBHASH CHANDER,
A;GOVERDHAN REDDY,V; RAO, MHV RAMANA;KUNWAR,
AC; Radical react ions on enol-est ers: facile synt hesis of
3-ulosonic acid derivat es And chiral spiroacet als
SHARMA, GVM;REDDY, CG;KRISHNA, PR; Zi rconi um(IV)
Chl ori de cat al yzed new and ef f i ci ent prot ocol f or t he
select ive Cleavage of p-Met hoxybenzyl et hers
4575
SHARMA, GVM;REDDY, CG;KRISHNA, PR; A si mpl e and
effi ci ent prot ocol for t he deprenyl at i on of et hers and
est er s cat al ysed b y Zi r coni um(IV) chl or i d e-sod i um
iodide
Synlet t (2003) (11) : 1728-1730
SHARMA, GVM;REDDY, K RAVINDER;RADHAKRISHNA, P;
SANKAR, A RAVI;NARSIMULU, K;KUMAR, S KIRAN;
JAYAPRAKASH, P; JAYA PRAKASH, P;JAGANNADH,
B;KUNWAR, AC Robust Mi xed 10/ 12 Hel i cs promot ed
by Al t ernat i on chi ral i t y i n a New Fami l y Of C-Li nked
Carbo-bet a-pept i des
125(45) : 13670-13671
SHARMA, GVM;SRINIVAS, B;KRISHNA, PALAKODETY RADHA; A facile
zirconium(IV) chloride cat alysed select ive deprot ect ion of t -
but yldimet hylsilyl ( TBDMS) et hers
SMITHA, B;SRIDHAR, S;KHAN, AA; Synt hesi s of and
ch ar act er i sat i o n o f p r o t o n co n d u ct i n g p o l ymer
membranes for fuel cells
Journal of Membrane Science (2003) 225(1-2) : 63-76
SREEDHAR, B;BHASKAR, V;SRIDHAR, CH;SRINIVAS,
T;KTAI, L; SZENTMIHLYI, K; Acylat ion of alcohols and
amines wit h carboxylic acids: a first report cat alyzed by
iron(III) oxide-cont aining act ivat ed carbon
191(1) : 141-147
SRIDEVI, KV;VENKATESHAM, U;REDDY, AV; VENKATESWARLU, Y;
Chemical const it uent s of t he red alga Nit ophyllum marginat a
335-337
SRIDEVI, S;CHAUHAN, AS;CHALASANI, KB;JAIN, AK;
DIWAN, PV; En h an cemen t o f d i sso l u t i o n an d o r al
bioavailabilit y of gliquidone wit h hydroxy Propyl-bet a-
cycl odext ri n
Pharmazie (2003) 58(11) : 807-810
SRIDHAR, S;PRASAD, KK;MURTHY, GS;RAO, AG, KHAN, AA;
Processing of composit e indust rial effluent by reverse
osmosi s
Journal of Chemical Technology and Biotechnology
(2003) 78(10) : 1061-1067
SRIDHAR, S;SRINIVASAN, T;VIRENDRA, U;KHAN, AA;
Pervaporat ion of ket azine aqueous layer in product ion
of hydrazine hydrat e by peroxide process
Chemical Engineering Journal (2003) 94(1) : 51-56
SRIDHAR, S;SUSHEELA, G;MURTHY, GS;VEERAIAH,
G;RAMKRISHNA, M; Per vap or at i on p er f or man ce of
Deacet yl at ed Chi t osan membrane i n t he Dehydrat i on
of Acet one
Journal of Polymer Mat erials (2003) 20(1) : 9-16
SRINIVAS, K;MAITRAIE, D;RAO, PS;NARSAIAH, B; A facile
synt hesi s of 4-oxo-1,2,3,4-t et rahydropyri do [3 ,2 : 4,5]
f uro[3,2-d] Pyri di nes: A new t ri cycl i c het erocycl i c ri ng
syst em
I ndi an Journal of Chemi st ry Sect i on B - Organi c
Chemi st ry I ncl udi ng Medi ci nal Chemi st ry (2003)
42(3) : 605-610
Publications
166
SRINIVAS, KVNS;DAS, B; 9-Met hoxy-20-O-acet yl campt o
t hecin, a minor new alkaloid from Not hapodit es foet ida
85-87
SRINIVAS, KVNS;DAS, B; St ud i es on Novel Syn t het i c
met hodologies. Part 17. A highly convenient , efficient ,
And sel ect i ve process f or preparat i on of Est ers and
Ami d es f r o m Car b o xyl i c Aci d s Usi n g Fe3+ - K- 10
Mont mori l l oni t e Cl ay
1167
SRINIVAS, KVNS;MAHENDER, I;DAS, B; Efficient and rapid
one-p ot conver si ons of al d ehyd es i nt o ni t r i l es and
ket o n es i n t o ami d es u si n g si l i ca ch l o r i d e u n d er
mi crowave i rradi at i on
SRINIVAS, KVNS;MAHENDER, I;DAS, B; Si l i ca chl ori de: A
versat i l e het erogeneous cat al yst for est eri fi cat i on and
Transest eri f i cat i on
SRINIVAS, KVNS;RAO, YK;MAHENDER, I;DAS, B;RAMA
KRISHNA, KVS; HARA KISHORE, K;MURTY, USN;
Flavanoids from Caesalpinia pulcherrima
Phyt ochemist ry (2003) 63(7) : 789-793
SRINIVAS, KVNS;MAHENDER, I;DAS, B; Sel ect i ve
monoacet yl at i on of symmet ri cal di ol s and sel ect i ve
monodeacet ylat ion of symmet rical diacet at es using HY-
zeol i t e as reusabl e het erogenous cat al yst
Synlet t (2003) (15) : 2419-2421
SRINIVAS, S;PRAKASHAM, RS;SARMA, PN; Aer o b i c
ferment at ion of D.xylose present I sugarcane molasses
t o et hanol by Clavispora opunt iae
Asian J Microbiol. Biotechnol Environmental Sciences
(2003) 5(3) : 367-368
SUNDER, MS;PRASAD, DHL; Phase equilibria of wat er plus
furfural and dichloromet hane plus n-hexane
Journal Of Chemical And Engineering Dat a (2003)
48(2) : 221-223
SUNITA, M;RAO, DG; Bioconversion of mango processing
wast e t o f i sh-f eed by mi croal gae Isol at ed f rom f rui t
processi ng i ndust ri al ef f l uent s
Journal of Scient ific & Indust rial Research (2003)
62(4) : 344-347
SURENDRA, K;KRISHNAVENI, NSRILAKSHMI;NAGESWAR,
YVD; RAO, K RAMA; Highly Regioselect ive Ring Opening
of Oxiranes wit h Phenoxides in t he presence of bet a -
Cyclodext rin in Wat er
4995
SURENDRA, K;KRISHAVENI, N SRILAKSHMI;REDDY, M
ARJUN;NAGESHWAR, YVD;RAO, K RAMA; Mild oxidat ion
of al cohol s wi t h o-Iodoxybenzoi c aci d (IBX) i n wat er/
acet one mixt ure in t he presence of bet a-cyclodext rin
2059
SURENDRA, K; KRISHNAVENI, N SRILAKSHMI; REDDY, M
ARJUN; NAGESWAR, Y V D; RAO, K RAMA; Highly Select ive
Oxi d at i ve Cl eavag e of b et a-Cycl od ext r i n -Ep oxi d e/
Aziridine Complexes wit h IBX in Wat er
9121
SURESH, KI;SITARAMAM, BS;RAJU; Ef f ect of copol ymer
composit ion on t he dynamic mechanical and t hermal
bevavi our of but yl acryl at e-Acryl oni t ri l e copol ymer
Macromolecular Mat erials and Engineering (2003)
288(12) : 980-988
SWAMY, NR;VENKATESWARLU, Y; Mi l d and ef f i ci ent
met hod for regioselect ive ring opening of aziridines wit h
amines by Bismut h t richloride
SWAROOPA RANI, A;ANNAPURNA, JETTY; RAMA
KRISHNA, SV; Penicillin Product ion in cont inuous st irred
t ank react or by Penicillium chrysogenum Immobilized
in Agar
Chemical and Biochemical Engineering Quart erly
(2003) 17(2) : 119-122
167
THIMMA, REDDY T;REDDY, NS;TAMMISHETTI, S; Synt hesis
and charact eri zat i on of guar gum-graf t -pol yacryl oni
t ri l e
663-668
THIMMA, REDDY T;TAMMISHETTI, S; St udy of compl ex
coacervat i on of gel at i n wi t h sodi um carboxymet hyl
g u ar g u m: mi cr o en cap su l at i o n o f cl o ve o i l an d
sul phamet hoxazol e
Journal Of Microencapsulat ion (2003) 20(2) : 203-
210
TIETZE, LF;BELL, HP;CHANDRASEKHAR, S; Nat u r al
p r o d u ct h yb r i d s as n ew l ead s f o r d r u g d i sco ver y
[Review]
Angewandt e Chemie I nt ernat ional Edit ion (2003)
42(34) : 3996-4028
TIWARI, AK; Adverse effect s of ant ioxidant s
VARALA, R;ALAM, MM;ADAPA, SR; Ch emosel ect i v e
Michael t ype addit ion of aliphat ic amines t o alpha,bet a-
et hyl eni c Compounds usi ng bi smut h t ri f l at e cat al yst
Synlet t (2003) (5) : 720-722
VARALA, R;ALAM, MM;ADAPA, SR; Bi smut h t r i f l at e
cat alyzed one-pot synt hesis of 3,4-dihydropyrimidin-2
(1H)-on es: An i mp r oved p r ot ocol f or t h e Bi g i n el l i
react i on
Synlet t (2003) (1) : 67-70
VAIRAMANI, M;GROSS, ML; G-Quadruplex format ion of
t hrombi n bi ndi ng apt amer det ect ed by el ect rospray
i noi zat i on mass spect romet ry
125(1) : 42-43
VENKATAIAH, B;RAMESH, C;RAVINDRANATH, N;DAS, B;
Ch ar mi n ar o n e, a seco - p seu d o g u ai an o l i d e f r o m
Part heni um hyst erophorus
Phyt ochemist ry (2003) 63(4) : 383-386
VENUGOPAL, A;ALUJA, J;SCURRELL, MS; The wat er-gas
shi f t react i on over Au-based, bi met al l i c cat al yst s. The
Au-M (M= Ag, Bi, Co, Cu, Mn, Ni, Pb, Ru, Sn, Tl) on Iron (III)
oxi de syst em
VIJAYARAGHAVAN, R;SURIANARAYANAN, M;RAGHAVAN,
KV; St udies on synt hesis and charact erizat ion of charge
t ransfer pol ymeri zat i on of st yrene and al kyl met hacry
l at es
Journal of Macromolecular Science-Pure & Applied
Chemist ry (2003) A40(10):1057-1080
VOLETI, N;VAIRAMANI, M; Prot on af f i ni t y di f f erences
among t hr ee N-acet yl hexosami nes st ud i ed b y t he
ki net i c met hod
17(10) : 1089-1091
WULFF, H;RAO, MM;SCHOLZ, F; Cryst allographic Evidence
f or t he f or mat i on of a cont i nuous ser i es of mi xed
0Cryst als bet ween NiO and LiNiO
2
Chemist ry of Mat erials (2003) 15(4) , 988-993
YADAV, JS;ANURADHA, K;REDDY, BV SUBBA;
EESHWARAIAH, B; Mi cr owave-accel er at ed conj ugat e
addi t i on of al dehydes t o ,-unsat urat ed ket ones
YADAV, JS;BABU, RS;SABITHA, G; St ereosel ect i ve t ot al
synt hesi s of (+)-art emi si ni n
,
YADAV, JS;BABU, R SATHEESH;SABITHA, G; Tot al synt hesis
of (+) art emisinin
ARKIVOC (Gainesville, FL, Unit ed St at es) (2003) (3) :
125-139
YADAV, JS;GEETHA, V;RAJU, AK;GNANESHWAR, D;
CHANDRASEKHAR, S; The first t ot al synt hesis of t he 6-
hydroxy-4E-sphi ngeni nes
Publications
168
YADAV, JS;RAJAIAH, G;RAJU, AK; A conci se and st ereo
select ive synt hesis of bot h enant iomers of alt holact one
and i soal t hol act one
YADAV, JS;REDDY, BVS; Mi cr ow ave- assi st ed r ap i d
syn t h esi s o f n eu r o t r an smi t t er r el ease en h an cer
linopiridine And it s new analogues
YADAV, JS;REDDY, BVS;BAISHYA, GAKUL; InBr3-[bmi m]
PF6: a novel and recycl abl e cat al yt i c syst em f or t he
synt hesis of 1,3-dioxane derivat ives
Green Chemist ry (2003) 5(2) : 264-266
YADAV, JS;REDDY, BVS;BAISHYA, GAKUL; Green prot ocol
f o r co n j u g at e ad d i t i o n o f t h i o l s t o al p h a, b et a-
unsat urat ed ket ones Using [Bmim] PF(6) IF (2) O syst em
7100
YADAV, JS;REDDY, BVS;BAISHYA, GAKUL; In d i u m
t ribromide: A novel and highly efficient reagent for t he
conversion of Oxiranes t o t hiiranes
Synlet t (2003) (3) : 396-398
YADAV,JS; REDDY, BVS; BASAK, AK;NARSAIAH, AV; Aza-
Michael react ions in ionic liquids. A facile synt hesis of
bet a-ami no compounds
Chemist ry Let t ers (2003) 32(11):988-989
YADAV, JS;REDDY, BVS;BASAK, AK;NARSAIAH, AV; [Bmim]
PF
6
and BF
4
ionic liquids as novel and recyclable react ion
media for aromat ic aminat ion
YADAV, JS;REDDY, BVS;BASAK, AK;NARSAIAH, AV; [Bmim]
BF
4
i on i c l i q u i d : a n ovel r eact i on med i u m f or t h e
synt hesis of -amino alcohols
YADAV, JS;REDDY, BVS;BASAK, AK;NARSAIAH, AV; Three-
comp onent coup l i ng r eact i ons i n i oni c l i q ui d s: An
i mp roved p rot ocol f or t he synt hesi s of 1,4-di hydro
pyri di nes
Green Chemist ry (2003) 5(1) : 60-63
YADAV, JS;REDDY, BVS;ESHWARAIAH, B;SRINIVAS, M;
VISHNUMURTHY, P; Th r ee-comp o n en t co u p l i n g
r eact i o n s i n i o n i c l i q u i d s: a f aci l e syn t h esi s o f a-
Ami nononai t ri l es
New Journal of Chemist ry (2003) 27(3) : 462-465
YADAV, JS;REDDY, BVS;GAYATHRI, KU;PRASAD, AR;
[ Bmi m] PF6/ RuCl 3 cen t er d ot xH(2)O: a n ovel an d
recycl abl e cat al yt i c syst em f or t he oxi dat i ve coupl i ng
of bet a-napht hol s
YADAV, JS;REDDY, BVS;GEETHA, V; Scand i um t r i f l at e
cat alyzed t hioglycosidat ion of glycals: A facile synt hesis
of 2,3-Unsat urat ed t hi ogl ycopyranosi des
YADAV, JS;REDDY, BVS;GNANESHWAR, D; In Cl 3
i mmobi l i zed i n i oni c l i qui ds: a novel and recycl abl e
cat al yt i c syst em f o r t et r ah yd r o p yr an yl at i o n an d
furanylat ion of alcohols
YADAV, JS;REDDY, BVS;KONDAJI, G; InCl3-cat alyzed [3+2]
cycl oaddi t i on react i ons: A f aci l e synt hesi s of t rans-
d i h yd r ob en zof u r an s an d su b st i t u t ed cycl ob u t an e
deri vat i ves
YADAV, JS;REDDY, BVS;KONDAJI, G; Eco-f r i endl y and
h i g h l y ch emo sel ect i ve 1,3- o xat h i o - an d 1,3-
dit hioacet alizat ion of Aldehydes using ionic liquids
YADAV, JS;REDDY, BVS;KRISHNA, AD;SADASIV, K;CHARY,
CJ; Ceric(IV) ammonium nit rat e: A novel reagent for t he
synt hesi s of homoal l yl al cohol s
Chemistry Letters (2003) 32(3) : 248-249
YADAV, JS;REDDY, BVS;KRISHNA, AD;SWAMY, T; InBr3-
cat alyzed sulfonat ion of indoles: a facile synt hesis of 3-
sul fonyl i ndol es
169
YADAV, JS;REDDY, BVS;RAJU, AK; [Bmim]BF
4
ionic liquid:
A novel and recyclable react ion media for t he synt hesis
of homoallylic amines
YADAV, JS; REDDY, BVS; NARSIMHASWAMY, D; NARSIMULU,
K;KUNWAR, AC; LiClO
4
- or LiOTf-accelerat ed 1,3-dipolar
cycl oaddi t i on react i ons: a f aci l e synt hesi s of ci s-f used
chromano[4,3-c]i soxazol es
YADAV, JS;REDDY, BVS;PARIMALA, G; LiClO4-cat alysed C-
al kyl at i on of pyrrol e and i ndol es wi t h azi ri di nes and
epoxides
Journal of Chemical Research - S (2003) (2) : 78-81
YADAV, JS;REDDY, BVS;PREMALATHA, K; 1- Bu t yl - 3-
met hylimidazolium t et rafluoroborat e ([Bmim]BF
4
) ionic
liquid: A novel and recyclable react ion medium for t he
synt hesis of vic-diamines
Advanced Synt hesis & Cat alysis (2003) 345(8) : 948-
952
YADAV, JS;REDDY, BVS;RAJ, KS;PRASAD, AR; Room t empe rat ure
ionic liquids promot ed t hree-component coupling react ions: a
facile synt hesis of cis-isoquinolonic acids
Tet rahedron (2003) 59(10) : 1805-1809
YADAV, JS; REDDY, BVS; RAO, CV; REDDY, MS; Molecular
i odi ne-cat al yzed hi ghl y st ereosel ect i ve synt hesi s of
sugar acet yl enes
YADAV, JS;REDDY, BVS; RAO, KV; RAJ, KS; PRASAD, AR;
KUMAR, SK; KUNWAR, AC;JAYAPRAKASH, P;JAGANNATH,
B; InBr3-cat al yzed cycl i zat i on of gl ycal s wi t h aryl ami nes
Angewandt e Chemie-I nt ernat ional Edit ion (2003)
42(42) : 5198-5201
YADAV, JS;REDDY, BVS;RAO, MS;REDDY, PN; Li Cl O
4
-
cat al yzed hi ghl y di ast ereosel ect i ve synt hesi s of ci s-
aziridine carboxylat es
YADAV, JS;REDDY, BVS; RAO, RS;NAVEENKUMAR, V;
NAGAIAH, K; Mi crowave-assi st ed one-pot synt hesi s of
2,4- d i su b st i t u t ed q u i n o l i n es u n d er so l ven t - f r ee
condi t i ons
YADAV, JS; REDDY, BVS; REDDY, CHS; RAJASEKHAR, K; Bmim] PF(6):
A Novel and Recyclable Ionic Liquid for Conversion of
Oxiranes t o Thiiranes in Aqueous Media
The Journal of Organic Chemist ry (2003) 68(6) : 2525-
2527
YADAV, JS;REDDY, BVS;REDDY, KB;GAYATHRI, KU;PRASAD,
AR; Gl aser o xi d at i ve co u p l i n g i n i o n i c l i q u i d s: an
improved synt hesis of conj ugat ed 1,3-diynes
YADAV, JS;REDDY, BVS;SUNITHA, V;REDDY, KS; Novel use
o f Sel ect f l u o r ( TM) f o r t h e syn t h esi s o f ci s- f u sed
pyranoand Furanot et rahydroqui nol i nes
1206
YADAV, JS;REDDY, BVS;REDDY, JSS;RAO, RS; Aza-Di el s
Al der react i ons i n i oni c l i qui ds: a f aci l e synt hesi s of
pyrano- and Furanoqui nol i nes
Tet rahedron (2003) 59(9) : 1599-1604
YADAV, JS; REDDY, BVS; REDDY, KS; Ul t r aso u n d -
accelerat ed synt hesis of chiral allylic alcohols promot ed
by Indium met al
Tet rahedron (2003) 59(28) : 5333-5336
YADAV, JS;REDDY, BVS;REDDY, MS; El ement al i odi ne-
cat alyzed coupling of alkynylsilanes wit h acid chlorides:
A facile synt hesis of alpha,bet a-acet ylenic ket ones
Synlet t (2003) (11) : 1722-1724
YADAV, JS;REDDY, BVS;REDDY, MS;NIRANJAN, N;PRASAD, AR; Lewis
acidic chloroaluminat e ionic liquids: Novel react ion media for
t he Synt hesis of 4-chloropyrans European
Journal of Organic Chemist ry (2003) (9) : 1779-1783
Publications
170
YADAV, JS;REDDY, BVS;REDDY, PN;RAO, MS; Bi (OTf )(3)-
[Bmi m]PF6: A novel and reusabl e cat al yt i c syst em f or
t he synt hesis of cis-aziridine carboxylat es
Synt hesis-St ut t gart (2003) (9) :1387-1390
YADAV, JS;REDDY, BVS;REDDY, MS;PARIMALA, G; InBr3-
cat alyzed alkynylat ion and allylat ion of acid chlorides:
A facile Synt hesis of alkynyl and allyl ket ones
YADAV, JS;REDDY, BVS;REDDY, PSR;REDDY, KS;REDDY,
PN; A novel approach f or t he synt hesi s of di pyrrol yl
alkanols and dipyrrolyl alkylamines
Synlet t (2003) (3) : 417-419
YADAV, JS;REDDY, BVS;SATHEESH, G; Bi(Ot f )3-cat alyzed
al l yl at i on of epoxi des:a faci l e synt hesi s of homoal l yl i c
al cohol s
YADAV, JS;REDDY, BVS;SATHEESH, G; In Br 3/ Cu (Ot f )2-
cat al yzed C-al kyl at i on of p yr r ol es an d i n d ol es w i t h
d i azo car b o n yl
YADAV, JS;REDDY, BVS;SATHEESH, G;PRABHAKAR,
A;KUNWAR, AC; Un p r eced en t ed In Cl
3
-cat al yzed
format i on of ci s-fused perhydrofuro[2,3-b]oxepi nes
YADAV, JS;REDDY, BVS;SREEDHAR, P; Three-component
one-pot synt hesis of alpha-hydroxylamino phosphat es
using ionic liquids
Advanced Synthesis and Catalysis (2003) 345(5) : 564-
567
YADAV, JS;SRINIVAS, C; Ring expansion approach for t he
synt hesi s of t he (3S,4S)-hexahyd r oazep i ne cor e of
balanol and ophiocordin
Tet rahedron (2003) 59(51) : 10325-10329
YADAV, JS; REDDY, BVS; SRINIVAS, M; Green prot ocol for
t he O-H insert ion of alpha-diazoket ones wit h alcohols
And wat er using ionic liquid [bmim]BF4
Chemist ry Let t ers (2003) 32(11):1060-1061
YADAV, JS;REDDY, BVS;SUNITHA, S; Ef f i ci ent and eco-
f ri endl y process f or t he synt hesi s of bi s(1H-i ndol -3-
yl)met hanes Using ionic liquids
352
YADAV, JS;REDDY, BVS;SWAMY, T; Bi (OTf )3-cat al yzed
allylat ion of quinones wit h allylt rimet hylsilane
YADAV, JS;REDDY, BVS;SWAMY, T; Bi(OTf )(3)-cat alyzed a
f aci l e conj ugat e addi t i on of i ndol es t o p -qui nones:
synt hesis of 3-indolyl quinines
Tet rahedron Let t ers (2003) 44(51): 9121-9124
YADAV, JS;REDDY, BVS;VISHNUMURTHY, P; LIBF4: a mild
a novel reagent f or t he OH i nsert i on react i ons of -
di azoket ones
171
ABBO, HS; TINTINCHI, SJJ; CHAND, S; PRASAD, R;
Invest i gat i on of [Ni {Me4Bzo2[14]aneN4}]Cl 2 cat al yzed
select ive hydroxylat ion of phenol t o cat echol by H202
in t he homogeneous medium
218(2) : 125-132
AMARNATH, CA; SARAVANAN, C;PALANIAPPAN, S;
Preparat ion of benzyl acet at e using polyaniline salt s as
cat alyst s Part II
Polymers for Advanced Technologies (2004) 15(3): 18-
121
AMINABHAVI, TEJRAJ M;VIJAYA KUMAR NAIDU,
B;SRIDHAR, S; Comput er si mul at i on and comparat i ve
st udy on t he pervaporat i on separat i on charact eri st i cs
of sod i um al gi nat e and i t s b l end memb r anes wi t h
poly(vinyl alcohol) t o separat e aqueous mixt ures of 1,4-
di oxane or t et rahydrof uran
Journal of Applied Polymer Science (2004) 94(4) :
1827-1840
ANITHA, K;MOHAN, SV;REDDY, S JAYARAMA; Devel op-
ment of acet ylcholinest erase silica solgel immobilized
b i o sen so r an ap p l i cat i o n t o w ar d s o xyd emet o n
met hyl det ect i on
Biosensors and Bioelect ronics (2004) 20(4) : 848-856
ANJAIAH, SIDDAM;CHANDRASEKHAR, SRIVARI;GREE,
RENE Synt hesi s and prel i mi nary use of novel acryl i c
est er-derived t ask-specific ionic liquids
ANJAIAH, SIDDAM;CHANDRASEKHAR, S;GREE, RENE;
Carbon-Ferri er rearrangement s i n i oni c l i qui ds usi ng
Yb(OTf )
3
as cat al yst
214(1) : 133-136
2004 2004 2004 2004 2004
ANJAIAH, SIDDAM;CHANDRASEKHAR, S;GREE, RENE;
St et t er react ion in room t emperat ure ionic liquids and
applicat ion t o t he synt hesis of haloperidol
Advanced Synt hesis and Cat alysis (2004) 346(11) :
1329-1334
ANNAPURNA, JETTY;CHOWDARY, IP;LALITHA, G;
RAMAKRISHNA, SV; IYENGAR, DS; Ant imicrobial act ivit y
of euphorbia nivulia leaf ext ract
Pharmaceut ical Bot any (2004) 42(2) : 91-93
ANNAPURNA, JETTY;KRISHNA PRASAD, G;VENKAT
NAIDU, G;RAO, A GANGANI; Enumerat ion of anaerobic
bact eria from upflow anaerobic sludge blanket (uasb)
r eact o r f o r t h e t r eat men t o f ch emi cal i n d u st r y
wast ewat er
Asian Jl of Microbiol. Biot ech. Env. Science (2004)
6(2) : 253-258
ANURADHA, V;SRINIVAS, PV;RAO, J MADHUSUDANA;
Isolat ion and synt hesis of isodihydropiperlonguminine
Nat ural Product Research (2004) 18(3) : 247-251
BARUMATI, BABITA;REDDY, K MADHUSUDAN REDDY;
SUNKARA, V MANORAMA; Tai l o r ed co n d u ct i vi t y
behavior in nanocryst alline nickel ferrit e
Applied Physics Let t ers (2004) 85(14) : 2833-2835
BASAK, PRATYAY;MANORAMA, SUNKARA V; PEO-PU/ PAN
semi -i nt er p enet r at i ng p ol ymer net w or ks f or SPEs:
i n f l u en ce o f p h ysi cal p r o p er t i es o n t h e el ect r i cal
charact eri st i cs
Solid St at e Ionics (2004) 167(1-2) : 113-121
BASAK, PRATYAY; MANORAMA, SUNKARA V; Po l y
(et h yl en e o xi d e)p o l yu r et h an e/ p o l y(acr yl o n i t r i l e)
semi -i n t er p en et r at i n g p ol ymer n et w or ks f or sol i d
polymer elect rolyt es: vibrat ional spect roscopic st udies
in support of elect rical behavior
European Polymer Journal (2004) 40(6) : 1155-1162
Publications
172
BEGUM, GHOUSIA; Car b of ur an i nsect i ci d e i nd uced
bi ochemi cal al t erat i ons i n l i ver and muscl e t i ssues of
t he fish Clarius bat rachus (linn) and recovery response
Aquat ic Toxicology (2004) 66(1) : 83-92
BINDU, P HIMA;SASTRY, G MADHAVI;MURTY, US;SASTRY,
G NARAHARI; St ruct ural and conf ormat i onal changes
concomit ant wit h t he E1E2 t ransit ion in H
+
K
+
-ATPase:
a comparat ive prot ein modeling st udy
Bi ochemi cal and Bi ophysi cal Resear ch
Communicat ions (2004) 319(2) : 312-320
BINDU, P HIMA;SASTRY, G MADHAVI;SASTRY, G
NARAHARI; Charact erizat ion of calcium and magnesium
binding domains of human 5-lipoxygenase
Bi ochemi cal and Bi ophysi cal Resear ch
Communicat ions (2004) 320(2) : 461-467
BHASKAR, G;SATISH KUMAR, V;RAO, B VENKATESWARA;
A short st ereoselect ive synt hesis of (-)-chloramphenicol
and (+)-t hiamphenicol
BHOGA, UMADEVI;MALI, RS;ADAPA, SRINIVAS R; New
synt hesis of linear furoquinoline alkaloids
BOSE, DS;KUMAR, RK;FATIMA, L; A r emar k ab l e r at e
accel erat i on of t he one-pot t hree-component cycl o-
co n d en sat i o n r eact i o n at r o o m t emp er at u r e: An
expedi ent synt hesi s of mi t ot i c Ki nesi n Eg5 i nhi bi t or
monast rol
Synlet t (2004) (2) : 279-282
CHAKRABORTY, TK; Crorepat i Sci ent i st
CHAKABORTY, TK;KRISHNA MOHAN, B;KUMAR, A
UDAY;PRABHAKAR, A;JAGADEESH, B; Synt hesi s of 3,4-
di -O-acyl at ed gl ucose-deri ved f uranoi d sugar ami no
aci d s (Gaa): Co n f o r mat i o n al an al ysi s o f a Leu -
enkephalin analog cont aining di-O-myrist oylat ed Gaa
CHAKRABORTY, TK;SRINIVASU, P;SAKUNTHALA
MADHAVENDRA, S; KIRAN KUMAR, S;KUNWAR, AC;
Conf ormat i onal st udi es of t he l i near homool i gomers
of a glucose-derived furanoid sugar amino acid
CHAKRABORTY, TK;SRINIVASU, P;SAKUNTHALA
MADHAVENDRA, S;KIRAN KUMAR, S;KUNWAR, AC;
Conf ormat i onal st udi es of t he l i near homool i gomers
of a gl ucose-deri ved f uranoi d sugar ami no aci d ( VOL
45, PG 3573, 2004)
CHAKRABORTY, TK;SRINIVASU, P;TAPADAR, S;MOHAN,
BK; Sugar ami no aci ds and rel at ed mol ecul es: Some
recent devel opment s
Journal of Chemical Sciences (2004) 116(4) : 187-207
CHAKRABORTY; TK; GOSWAMI,K RAJIB; Synt hesi s of
(3R,4S,5S,9S)-3,5,9-t rihydroxy-4-met hylundecanoic acid
-lact one
CHAKRABORTY, TK;TAPADAR, S;RAJU, TV;ANNAPURNA,
T;SINGH, H; Cyclic t imers of chiral furan amino acids
Synlet t (2004) : 2484-2488
CHAKRABORTY, TK;REDDY, VR;SUDHAKAR, G;KUMAR,
SU;REDDY, TJ; KUMAR, SK;KUNWAR, AC;MATHUR,
A;SHARMA, R;GUPTA, N;PRASAD, S; Conf or mat i onal
st u d i es of 3,4-d i d eoxy f u r an oi d su g ar ami n o aci d
cont aining analogs of t he recept or binding inhibit or of
vasoact i ve i nt est i nal pept i de
Tet rahedron (2004) 60(38) : 8329-8339
CHAKRABORTY, TK;SRINIVASU, P;RAO, R VENGAL;
KUMAR, S KIRAN; KUNWAR, AC; Conformat ional St udies
of Pept ides Cont aining cis-3-Hydroxy-d-proline
7399-7402
173
CHANDRASEKAR, DURAIRAJ; RAMAKRISHNA, SISTLA;
DIWAN, PRAKASH V; A rapi d, sensi t i ve and val i dat ed
met h o d f o r t h e d et er mi n at i o n o f o n d an set r o n i n
human plasma by reversed-phase high-pressure liquid
chromat ography
Arzneimit t el-Forschung (2004) 54(10) : 655-659
CHANDRASEKHAR, K;CHARY, NS;KAMALA, CT;SUMAN
RAJ, DS; RAO, A SREENIVASA; Fract ionat ion st udies and
bi oaccumul at i on of sedi ment -bound heavy met al s i n
Kolleru lake by edible fish
Environment Int ernat ional (2004) 29(7) : 1001-1008
CHANDRASEKHAR, K;KAMALA, CT;CHARY,NS; SASTRY,
ARK; RAO, T; NAGESWARA; VAIRAMANI, M; Removal of
lead from aqueous solut ions using an immobilized bio
mat erial derived from a plant bio mass
Journal of Hazardous Mat erials (2004) 108(1-2) : 111-
117
CHANDRASEKHAR, K;CHARY, NS;KAMALA, CT; ANJANEYULU, Y;
Ut ilizat ion of plant met al int eract ions for environment al
management : f r om a gener al di sb el i ef t o uni ver sal
accept ance
Proceedings of t he Indian Nat ional Science Academy,
Part B: Biological Sciences (2004) 70(1) : 13-30
CHANDRASEKHAR, K;GUPTA, KK;BHATTACHARYA,
S;CHAKRAVARTHY, S; The det ermi nat i on of gol d i n ore
samples by induct ively coupled Plasma Opt ical Emission
Spect romet ry
At omic Spect roscopy (2004) 25(4) : 165-169
CHANDRASEKHAR, S;CHANDRASHEKAR, B;NAGENDRA
BABU, K;VIJEENDER; REDDY, K VENKATRAM; Reduct i ve
et h er i f i cat i o n o f car b o n yl co mp o u n d s w i t h al kyl
t r i met hyl si l yl et her s usi ng p ol ymet hyl hydr osi l oxane
(PMHS) and cat alyt ic B(C6F5)3
CHANDRASEKHAR, S;JAGADESWAR, V;NARSIHMULU,
Ch;SARANGAPANI, M; KRISHNA, DR;VIDYASAGAR, J;VIJAY,
DOLLY;SASTRY, G NARAHARI; Desi gn, syn t hesi s and
cyt ot oxi c st u d i es on t h e si mp l i f i ed oxy an al og of
el eut herobi n
14(14) : 3687-3689
CHANDRASEKHAR, S;MURTHY, J KRISHNA;RAO, PK;RAO,
K S RAMA; St udies on t he modificat ion of Pd/ Al203 and
Pd / C syst ems t o d esi g n hi g hl y act i ve cat al yst s f or
hydrodechlorinat ion of CFC-12 t o HFC-32
Applied Cat alysis A: General (2004) 271(1-2) : 95-101
CHANDRASHEKAR, S;NAGENDRABABU, B;REDDY, M
VENKATA;SRIHARI, P;PRABHAKAR, A;JAGADEESH, B; Safe
and conveni ent r ed uct i on of
2
Isoxazol i nes wi t h
PHMS-Pd(OH)
2
/ C
Synlet t (2004) (7) : 1303-1305
CHANDRASEKHAR, S;NARSIHUMULU, Ch; CHANDRA
SHEKAR, G; SHYAMSUNDER; Pd / CaCO3 i n l i q u i d
poly(et hylene glycol) (PEG): an easy and efficient recycle
syst ems f or part i al reduct i on of al kynes t o ci s-ol ef i ns
under a hydrogen at mosphere
Tet rahedron Let t ers (2004) 45(11) 2421-2423
CHANDRASEKHAR, S;NARSIHMULU, Ch;REDDY, N RAMA
KRISHNA; SULTANA, S SHAMEEM; Asymmet r i c al d ol
react ions in poly(et hylene glycol) cat alyzed by -proline
CHANDRASEKHAR, S;NARSIHMULU, Ch;REDDY, N RAMA
KRISHNA;SULTANA, S SHAMEEM; l -Prol i ne cat al yzed
asymmet ric t ransfer aldol react ion bet ween diacet one
alcohol and aldehydes
Chemical Communicat ions (Cambridge, England)
(2004) (21) : 2450-2451
CHANDRASEKHAR, S;NARSIHMULU, Ch ;SARITHA,
B;SULTANA, S SHAMEEM; Pol y(et hyl enegl ycol ) (PEG): a
rapid and recyclable react ion medium for t he DABCO-
cat alyzed Baylis-Hillman react ion
Publications
174
CHARY, KVR;KUMAR, CHINTHALA PRAVEEN;RAO,
PENDYALA VENKAT; RAMANA;RAO, VATTIKONDA
VENKAT; Di sp er si on and r eact i vi t y of V
2
O
5
cat al yst s
support ed on Al
2
O
3
-ZrO
2
CHARY, KVR;RAJENDER REDDY, KONDAKINDI;KISHAN,
GURRAM; NIEMANTSVERDRIET, JW;MESTL, GERHARD;
St ruct ure and cat al yt i c propert i es of mol ybedenum
oxide cat alyst s support ed on zirconia
CHARY, KVR;RAJENDER REDDY, KONDAKINDI;KUMAR;
CHINTHALA PRAVEEN;NARESH;DHACHAPALLY;RAO,
VATTIKONDA VENKAT;MESTL, GERHARD Charact eri zat -
i on an d r eact i vi t y of mol yb d en um oxi d e cat al yst s
support ed on Nb
2
O
5
TiO
2
223(1-2) : 363-369
CHARY, KVR;SEELA, KK;SAGAR, GV;SREEDHAR, B;
Charact eri zat i on and react i vi t y of ni obi a support ed
copper oxide cat alyst s
Journal of Physical Chemist ry B (2004) 108(2) : 658-663
CHARY, KVR;SRI LAKSHMI, KATAR;RAO, P VENKAT
RAMANA;RAO, K SEETHA RAMA; PAPADAKI, MARIA;
Char act er i zat i on and cat al yt i c p r op er t i es of ni ob i a
support ed ni ckel cat al yst s i n t he hydrodechl ori nat i on
of 1,2,4-t richlorobenzene
223(1-2) : 353-361
CHATTOPADHYAY, DK;KUMAR, DBR;SREEDHAR, B;RAJU,
KVSN; Th er mal st ab i l i t y an d d yn ami c mech an i cal
behavior of acrylic resin and acrylic Melamine coat ings
Journal of Applied Polymer Science (2004) 91(1) : 27-34
CHATTOPADHYAY, DK;PANDA, SIVA SANKAR;RAJU, KVSN;
Propert i es of di ami ne chai n ext ended pol yuret hane
urea coat i ngs
Journal of t he Japanese Societ y of Color Mat erial
(2004) 77(12) : 540-547
CHANDRASEKHAR, S;NARSIHMULU, Ch ;SULTANA, S
SHAMEEM;REDDY, M SRINIVASA; The first st ereoselect ive
t ot al synt hesis of (6S)-5,6-dihydro-6-[(2R)-2-hydroxy-6-
phenylhexyl] -2H-pyran-2-one
CHANDRASEKHAR, S;PRAKASH, S;JAYA;SHYAMSUNDER,
T;RAMACHANDAR, T; Tant al um( V) chl ori de-cat al yzed
ring opening of aziridines wit h aromat ic amines
CHANDRASEKHAR, S;SHYAMSUNDER, T;CHANDRA
SHEKAR, G;NARSIHUMULU, C; Hyd r o g en at i o n an d
hydrogenolysis wit h Pd/ C in poly(et hylene glycol) (PEG):
A pract ical and recyclable medium
Synlet t (2004) (3) : 522-524
CHANDRASEKHAR, S;RAMACHANDAR, T;SHYAM
SUNDER, T; Appl i cat i ons of t ri val ent and pent aval ent
t ant al um i n organi c synt hesi s
I ndi an Jour nal of Chemi st r y Sect i on B Or gani c
Chemistry including Medicinal Chemistry (2004) 43(4)
: 813-838
CHANDRASEKHAR, S;REDDY, Ch RAJI;CHANDRASHEKAR,
G; Tr i s(p ent af l uorop henyl ) b orane cat al yzed Ferr i er
azagl ycosyl at i on wi t h Sul fonami des and carbamat es
CHANDRASEKHAR, S;REDDY, MAREPALLY SRINIVASA;
JAGADEESH, BHARATAM; PRABHAKAR, ANABATHULA;
RAMANA RAO, MALLEM HV; JAGANNADH, BULUSU
Format i on of a St abl e 14-Hel i x i n Short Ol i gomers of
Furanoi d ci s-bet a-Sugar-Ami no Aci d
Journal of t he American Chemical Societ yy (2004)
126(42) : 13586-13587
CHARY, KVR; KUMAR, CHINTHALA PRAVEEN; MURALI, AYALURU;
TRIPATHI, AKHILESH;CLEARFIELD, ABRAHAM; St udies on cat alyt ic
funct ionalit y of V2O5/ Nb2O5 cat alyst s
216(1) : 139-146
175
CHATTOPADHYAY, DK;SREEDHAR, B;RAJU, KVSN; Ef f ect
o f ch ai n ext en d er o n p h ase mi xi n g an d co at i n g
propert i es of pol yuret hane ureas
IEC Phase Mixing and Coat ing Propert ies (2004) : A-H
CHAUHAN, AS;JAIN, NK;DIWAN, PV;KHOPADE, AJ;
So l u b i l i t y en h an cemen t o f i n d o met h aci n w i t h
p o l y(ami d o ami n e) d en d r i mer s an d t ar g et i n g t o
i nfl ammat ory regi ons of art hri t i c rat s
Journal of Drug Target ing (2004) 12(9-10) : 575-583
CHOUDHARY, BM; Preface
223(1-2) : 15
CHOUDARY, BM;JYOTHI, K;KANTAM, ML;SREEDHAR, B;
Achi ral di hydroxyl at i on of ol efi ns by osmat e (OsO42-)
st abilized on nanocyst alline magnesium oxide
Advanced Synt hesis & Cat alysis (2004) 346(1) : 45-48
CHOUDARY, BM;JYOTHI, K;MADHI, S;KANTAM, ML;0
Allylat ion of aldehydes, aldimines and ring opening of
t erminal aromat ic epoxides by scandium t riflat e using
p ol yet hyl ene gl ycol (PEG) as an ef f i ci ent recycl ab l e
medi um
Synlet t (2004) (2) : 231-234
CHOUDARY, BM;JYOTHI, K;ROY, M;KANTAM, ML;
SREEDHAR, B; Bi f u n ct i o n al cat al yst s st ab i l i zed o n
nanocryst alline magnesium oxide for one-pot synt hesis
of chiral diols
1471-1480
CHOUDARY, BM;KANTAM, ML;RANGANATH, KVS;
MAHENDER, K;SREEDHAR, B; Bifunct ional nanocryst alline
Mg O f or chi r al ep oxy ket ones vi a Cl ai sen-Schmi d t
condensat i on-asymmet ri c epoxi dat i on react i ons
126(11) : 3396-3397
CHOUDARY, BM;KANTAM, ML;RANGANATH, KVS;RAO,
KK; Hyd r o g en p r o cessi n g b y FeIII- exch an g ed
mo n t mo r i l l o n i t e: A u n i q u e g eo ch emi cal p r o t o co l
Angewandt e Chemie I nt ernat ional Edit ion (2004)
44(2) : 322-325
CHOUDARY, BM;MADHI, S;KANTAM, ML;SREEDHAR,
B;IWASAWA, Y; Synt hesi s of sur f ace organopal l adi um
i nt ermedi at es i n coupl i ng react i ons: The mechani st i c
i nsi ght
126(8) : 2292-2293
CHOUDARY, BM;MADHI, S;KANTAM, ML;SREEDHAR,
B;IWASAWA, Y; Synt hesi s of sur f ace organopal l adi um
i nt ermedi at es i n coupl i ng react i ons: t he mechani st i c
insight . [Errat um t o document cit ed in CA140:321498]
126(21) : 6833
CHOUDARY, BM;REDDY, Ch VENKAT;VEDA PRAKASH,
B;BHARATHI, B;KANTAM, ML; Oxidat ion of secondar y and
t ert iary amines by a solid base cat alyst
217(1-2) : 81-85
CHOUDARY, BM;SRIDHAR, C;KANTAM, ML;SREEDHAR, B;
Hydroxyapat it e support ed copper cat alyst for effect ive
t hree-component coupl i ng
Tet rahedron Let ters (2004) 45(39) :7319-7321
CHOUDARY, BM;SRIDHAR, C;SATEESH, M;SREEDHAR, B;
Mi cr oencap sul at ed b i smut h (III) t r i f l at e cat al yst f or
organi c t ransf ormat i ons
Journal of Molecular Cat alysis A-Chemical (2004)
212(1-2) : 237-243
CHOUDARY, BM;SOMESHWAR, T;LAKSHMI KANTAM,
M;REDDY, Ch VENKAT; Mol ybdat e-exchanged MgAl
LDH cat alyst : an eco-compat ible rout e for t he synt hesis
of -bromost yrenes i n aqueous medi um
Publications
176
DAS, B;HOLLA, HARISH;MAHENDER, GURRAM;BANERJEE,
JOYDEEP; REDDY, M RAVINDER; Hyp er val en t i odi ne-
med i at ed i n t er act i on of al d oxi mes w i t h act i vat ed
al kenes i ncl udi ng Bayl i s-Hi l l man adduct s: a new and
ef f i ci ent met hod f or t he preparat i on of ni t ri l e oxi des
from al doxi mes
DAS, B;MAHENDER, GURRAM;KUMAR, VOOTURI
SUNIL;CHOWDHURY, NIKHIL; Chemoselect ive deprot ect -
i o n o f t r i t yl et h er s u si n g si l i ca-su p p o r t ed so d i u m
hydrogen sul f at e
DAS, B;REDDY, M RAVINDER;RAVINDRANATH, N;REDDY,
V SAI;VENKATESWARLU, K A; si mp l e an d ef f i ci en t
t et rahydropyranyl at i on usi ng N-bromosucci nami de
Indian Journal of Chemist ry B (2004) 43 B : 1711-
1712
DAS, B;REDDY, M RAVINDER;REDDY, V SAIDI;RAMU, R;
Novel and ef f i ci ent Lewi s aci ds as cat al yst s f or si ngl e
st ep synt hesis of pyrano and furnoquinolines
DAS, B;REDDY, V SAIDI;REDDY, M RAVINDER; An efficient
and sel ect i ve t osyl at i on of al cohol s wi t h p -t ol uene
sulfonic acid
DAS, B;REDDY, V SAIDI; ZrCl
4
as an efficient cat alyst for
select ive t osylat ion of alcohol s wit h p-t oluenesulfonic
acid
DAS, B;SRINIVAS, KVNS;MAHENDER, I;RAVINDRANATH,
N;RAMESH, C; A convenient met hod for t he preparat ion
of 7-cyan ocamp t ot h eci n s an d 7-cyan om ap p i ci n e
ket ones
DANADEVI, K;ROZATI, R;BANU, BS;GROVER, P; Genot oxic
eval u at i o n o f w el d er s o ccu p at i o n al l y exp o sed t o
ch r o mi u m an d n i ckel u si n g t h e co met an d
mi cronucl eus assays
Mut agenesis (2004) 19(1) 35-41
DANADEVI, K;ROZATI, R;BANU, B SALEHA;GROVER, P; In
vi vo Gen o t o xi c ef f ect o f n i ckel ch l o r i d e i n mi ce
l eukocyt es usi ng comet assay
Food And Chemical Toxicology (2004) 42(5) : 751-757
DAS, B;BANERJEE, JOYDEEP; Si l i ca support ed sodi um
hydrogen sul f at e and amberl yst -15: Two ef f i ci ent and
het erogeneous cat al yst s for si ngl e-st ep synt hesi s of 4
(3H)-quinazolines from ant hranilic acid, ort hoest ers and
amines under solvent free condit ions
DAS, B;BANERJEE, JOYDEEP;MAHENDER, GURRAM;
MAJHI, A; Organic react ions in wat er: An efficient Zinc
med i at ed st er eo sel ect i ve syn t h esi s o f (E)- an d (Z)-
t ri subst i t ut ed al kenes usi ng unact i vat ed al kyl hal i des
Organic Let t ers (2004) 6( 19) : 3349-3352
DAS, B;BANERJEE, JOYDEEP;MAJHI, ANJOY;MAHENDER,
GURRAM; An effi ci ent st ereosel ect i ve synt hesi s of (E)-
and (Z)-t risubst it ut ed alkenes from unact ivat ed Baylis
Hillman adduct s using NaBH
4
/ CuCl
2
2H
2
O
DAS, B;BANERJEE, JOYDEEP;RAVINDRANATH, NASI; A
si mpl e and faci l e st ereosel ect i ve synt hesi s of (Z)- and
(E)-al l yl hal i des cat al yzed by si l i ca support ed sodi um
hydrogen sul f at e: f act ors i nf l uenci ng t he yi el ds and
st ereochemist ry of allyl halides
Tet rahedron (2004) 60(38) : 8357-8361
DAS, B; BANERJEE, JOYDEEP; RAVINDRANATH, NASI;
VENKATAIAH, BOLLU; Conven i en t an d ef f i ci en t
st ereoselect ive synt hesis of (2Z)-2-(chloromet hyl)alk-2-
enoat es using iron(III) or indium(III) chloride
177
DAS, B;VENKATESWARLU, K;MAHENDER, G;HOLLA, H;
Synt hesis of coumarins via a Pechmann condensat ion
usi ng het erogeneous cat al yst s
Journal of Chemical Research (2004) (12) : 836-837
DAS, R;REDDY, V SAIDI;VENKATESWARLU, K;DAS, B; New
an h yd r o p o r t h en i n an al o g u es f r o m Par t h en i u m
hyst erop horus
I ndi an Journal of Het erocycl i c Chemi st ry (2004)
14(1) : 59-60
DAS, PIYALI;SREELATHA, T;GANESH, ANURADDA; Bio oil
from pyrolysis of cashew nut shell-charact erizat ion and
rel at ed propert i es
Biomass and Bioenergy (2004) 27(3) : 265-275
DEVI, SS;MALATHI, R;RAJAN, SS;ARAVIND, S;KRISHNA
KUMARI, GN;RAVIKUMAR, K; A neo-clerodane dit erpene
from Teucri um t oment osum
Act a Cryst allographica Sect ion E (St ruct ure Rep.
Online) (2004) 60(Part 1) : 0117-0119
DINADAYALANE, TC; DEEPA, S; REDDY, A SRINIVAS; SASTRY,
G NARAHARI; Densi t y f unct i onal t heory st udy on t he
effect of subst it ut ion and ring annelat ion t o t he rim of
corannul ene
8111-8114
DINADAYALANE, TC;PRIYAKUMAR, UD;SASTRY, GN;
Exp l o r at i o n o f C6H6 p o t en t i al en er g y su r f ace: A
comput at i onal effort t o unravel t he rel at i ve st abi l i t i es
and synt het ic feasibiligy of new benzene isomers
Journal of Physi cal Chemi st ry A (2004) 108(51) :
11433-11448
FADNAVIS, NW;RADIHIKA, R KASIRAMAN ;Enant i o- and
r egi osp eci f i c r educt i on of et hyl 4-p henyl -2,4-di oxo
but yrat e wit h baker s yeast : preparat ion of (R) HPB est er
FADNAVIS, NW;RADHIKA, R KASIRAMAN;MADHURI, KV;
Gelozymes in organic synt hesis Part 3: Lipase mediat ed
synt hesi s of enant i omeri cal l y p ure ( R ) and (S)
enant iomers of 2-acet oxy-4-phenyl-(E)-but 3-enenit rile
Tet rahedron : Asymmet ry (2004) 15(3) : 549-553
GANGADASU, B;PALANIAPPAN, S;RAO, VJ; On e-p ot
synt hesi s of di hydropyri mi di nones usi ng pol yani l i ne-
bi smocl i t e compl ex. A f aci l e and reusabl e cat al yst f or
t he Biginelli react ion
Synlet t (2004) (7) : 1285-1287
GANGADASU, B.; NARENDER, P.; RAJU, B. CHINA; RAO, V.
JAYATHIRTHA; ZrCl
4
cat alyzed solvent free synt hesis of
coumari ns
GANESH, I;JOHNSON, R;MAHAJAN, YR;KHAN,
A;MADHAVENDRA, SS;REDDY, BM; Mi crowave-i nduced
comb ust i on syn t h esi s of n an ocr yst al l i n e Ti O
2
-Si O
2
binary oxide mat erial
Journal of Mat erials Research (2004) 19(4) : 1015-
1023
GARCIA, A;PRABHAKAR, S;BROCK, CJ;PEARCE, AC;DWEK,
RA;WATSON, SP;EBESTREIT, HF;ZITZMANN, N; Ext ensive
an al ysi s of t h e h uman p l at el et p r ot eome b y t w o-
d i men si o n al g el el ect r o p h o r esi s an d mass
spect romet ry
Prot eomics (2004) (4) : 656-668
GARCIA, A;PRABHAKAR, S;HUGHAN, S;ANDERSON,
TW;BROCK, CJ; PEARCE, AC;DWEK, RA;WATSON,
SP;HEBESTREIT, HF;ZITZMANN, N; Different ial prot eome
anal ysi s of TRAP-act i vat ed pl at el et s: i nvol vement of
DOK-2 and phosphorylat ion of RGS prot eins
Blood (2004) 103 : 2088-2095
Publications
178
JAGADEESH, B;DEMCO, DE;BLUMICH, B; Sur face induced
order and dynamic het erogeneit y in ult ra t hin polymer
films: A 1
H
mult iple-quant um NMR st udy
Chemical Physics Let t ers (2004) 393(4-6) : 416-420
JAGADEESH, B;PRABHAKAR, A;RAO, MHV RAMANA;
MURTY, CVS;PISIPATI, VGKM;KUNWAR, AC;BOWERS, CR;
Pr ob i n g an i sot r op i c en vi r on men t of t h er mot r op i c
liquidcryst al using
129
Xe NMR spect roscopy
Journal of Physical Chemist ry B (2004) 108(31) :
11272-11279
JAGANNADH, B;REDDY, SS;THANGAVELU, RP;
Co n f o r mat i o n al p r ef er en ces o f 1,4,7-
t rit hiacyclononane: a molecular mechanics and densit y
f unct i onal t heory st udy
Journal of Molecular Modeling (2004) 10(1) : 55-59
JAMIL, K;SHAIK, AP;MAHBOOB, M;KRISHNA, D; Effect of
or g anop hosp hor us and or g anochl or i ne p est i ci d es
(mo n o cr o t o p h o s, ch l o r p yr i p h o s, d i met h at e an d
endosulfan) on hum lymphocyt es in vit ro
Drug and Chemical Toxicology (2004) 27(2) : 133-144
JAYALAKSHMI, M;RAO, M MOHAN;CHOUDARY, BM;
Ident i f yi ng nano SnS as a new el ect rode mat eri al f or
elect rochemical capacit ors in aqueous solut ions
El ect rochemi st ry Communi cat i ons (2004) 6(11) :
1119-1122
KAMAL, A;CHOUHAN, GAGAN; Invest i gat i ons t owards
t h e ch emo sel ect i ve t h i o acet al i zt i o n o f car b o n yl
co mp o u n d s b y u si n g i o n i c l i q u i d [ b mi m] Br as a
recyclable cat alyt ic medium
582
GOPINATH, RAJESH;LINGAIAH, N;BABU, N
SESHU;SURYANARAYANA, I;SAI PRASAD, PS;OBUCHI,
AKIRA; A h i g h l y act i ve l o w Pd co n t en t cat al yst
synt hesi zed by deposi t i onpreci pi t at i on met hod f or
hydrodechl ori nat i on of chl orobenzene
223(1-2) : 289-293
GOVIND, MM;SELVANAYAGAM, S;VELMURUGAN, D;
RAVIKUMAR, K; SURESH BABU, AR; RAGHUNATH, R; 1-(2-
Chlorophenyl)-1H-indan-2-spiro2-pyrrolizidine-3-spiro-
3-1H-indole-1,3,2 (2H,3H)-t rione
Online) (2004) 60(Part 1) : 054-056
D;RAVIKUMAR, K;SURESH BABU, AR;RAGHUNATH, R;
1-benzoyl acenapht hyl ene-1-spi ro-3-pyrrol i zi di ne-2-
spiro-3-1H-indole-2,2 (1H,3 H)-dione
Act a Cryst allographica Sect ion E (St ru Rep Online)
(2004) 60(Part 1):057-059
D;RAVIKUMAR, K;SURESHBABU, AR;RAGHUNATHAN, R;
1 -(4-met h ox yb en zo yl )acen ap h t h en e-1-sp i r o -3 -
pyrrolizidine-2 -spiro-3-1H-indole-2,2 (1H,3 H)-dione
Acta Crystallographica, Section E (Stru Reports Online)
(2004) 60(Part 5) :O873-O875
1 - m e t h y l - 4 - p h e n y l ac e n ap h t h e n e - 1 - sp i r o - 2 -
pyrrolidine-3 -spiro-2-indan-2,1 3 ,-t rione
Act a Cryst allographica, Sect ion E (St ru Rep Online)
(2004) 60(Part 4):O547-O549
HEMA, R;PARTHASARATHI, V;RAVIKUMAR, K;SARKUNAM,
K; NALLU, M; Di met h yl 3-b en zo yl -7-(N,N-d i met h y
l ami no)i ndol i zi ne-1,2-di carboxyl at e
Act a Cryst allographica, Sect ion E (St ru Rep Online)
(2004) 60(Part -4):O479-O480
179
KAMAL, A;CHOUHAN, GAGAN; Ch emo en zymat i c
synt hesis of enant iomerically pure 1,2-diols employing
immobilized lipase in t he ionic liquid [bmim]PF
6
KAMAL, A;KUMAR, B ASHWINI;ARIFUDDIN, M;PATRICK,
MIDOUX; An efficient and facile nit rat ion of phenols wit h
nit ric acid/ zinc chloride under ult rasonic condit ions
Ult rasonics Sonochemist ry (2004) 11(6) : 455-457
KAMAL, A; LAXMAN, E; KHANNA, GB RAMESH; REDDY,
PSMM; TASNEEM, REHANA; ARIFUDDIN, M; NEELIMA, K;
KONDAPI, ANAND K; DASTIDAR, SUNANDA G; Design,
synt hesi s, bi ol ogi cal eval uat i on and QSAR st udi es of
novel bisepipodophyllot oxins as cyt ot oxic agent s
Bioorganic and Medicinal Chemist ry (2004) 12(15) :
4197-4209
KAMAL, A; RAMANA, A VENKATA; REDDY, K SRINIVAS
A; RAMANA, K VENKATA; HARI BABU; A; RAJENDRA
PRASAD, B; One pot conversi on of azi do arenes t o N-
arylacet amides and N-arylformamides: synt hesis of 1,4-
b en zo d i azep i n e- 2,5- d i o n es an d f u sed
[2,1-b]qui nazol i nones
KAMAL, A;RAMESH, G;SRINIVAS, O;RAMULU, P; Synt hesis
an d an t i t u mo u r act i vi t y o f p yr en e-l i n ked p yr r o l o
[2,1-c][1 and 4] benzodiazepine hybrids
14(2) : 471-474
KAMAL, A; RAMESH, G;SRINIVAS, O; RAMULU,P; LAXMAN,N; REHANA,
TASNEEM; DEEPAK, M; ACHARY, MS; NAGARAJARAM, HA; Design,
synt hesis, and evaluat ion of mixed imine-amine pyrroloben
zodi azepi ne di mers wi t h ef f i ci ent DNA bi ndi ng af f i ni t y and
pot ent cyt ot oxicit y
Bioorganic & Medicinal Chemist ry (2004) 12(20) :
5427-5436
KAMAL, A; SHAIK, AHMAD ALI; SANDBHOR, M; MALIK,
M SHAHEER; Synt hesi s of enant i opure-azi doal cohol s
f rom t hei r ket oazi des by reduct i on wi t h NaBH
4
i n t he
presence of alumina and in sit u lipase resolut ion
KAMAL, A;REDDY, PSMM;REDDY, RAJASEKHAR D; The
ef f ect of C
2
-f l uoro group on t he bi ol ogi cal act i vi t y of
DC-81 and it s dimmers
14(10) : 2669-2672
KAMAL, A;REDDY, K LAXMA;REDDY, G SURESH
KUMAR;REDDY, BS NARAYAN; Sel ect i ve reduct i on of
aromat ic azides wit h hexamet hyldisilat hiane: synt hesis
of new 2-azidopyrrolo[2,1-c][1,4]benzodiazepines
KAMAL, A;RAJENDRA PRASAD, B;VENKATA RAMANA,
A;HARI BABU, A; REDDY, K SRINIVAS; FeCl
3
NaI mediat ed
react i ons of aryl azi des wi t h 3,4-di hydro-2H-pyran: a
convenient synt hesis of pyranoquinolines
KAMAL, A;RAMULU, P;SRINIVAS, O;RAMESH, G;KUMAR, P
PRAVEEN; Syn t hesi s of C
8
-l i nked p yr rol o[ 2,1-c] [ 1,4]
b en zo d i azep i n e- b en zi mi d azo l e co n j u g at es w i t h
remarkable DNA-binding affinit y
14(18) : 4791-4794
KAMAL, A;RAMU, R;KHANNA, GB RAMESH;SAXENA, AJIT
KUMAR; SHANMUGAVEL, M;PANDITA, RENU MOTI ;
Py r r o l o [ 2,1- c] [ 1,4] b en zo d i azep i n e- an t r aq u i n o n e
conj ugat es. Synt hesis, DNA binding and cyt ot oxicit y
14(19) : 4907-4909
Publications
180
KAMAL, A;REDDY, PSMM;REDDY, D RAJA SEKHAR;
LAXMAN, E;MURTHY, YLN; Syn t h esi s of f l uor i n at ed
analogues of SJG-136 and t heir DNA-binding pot ent ial
14(22) : 5699-5702
KAMAL, A;SHAIK, AHMAD ALI;SANDBHOR, MAHENDRA;
MALIK, M SHAHEER; KAGA, HARUMI; Chemoenzymat ic
syn t h esi s o f (3S,4S)- an d (3R,4R)- 3- met h o xy- 4-
met hyl ami nopyrrol i di ne
KAMAL, A; SHAIK, AHMAD ALI; SANDBHOR, MAHENDRA;
MALIK, M SHAHEER; Chemoenzymat ic synt hesis of (R)-
and (S)-t embamide, aegeline and denopamine by a one-
pot lipase resolut ion prot ocol
KANNAN, V; Diazabicyclo[2.2.2]oct ane DABCO;
Synlet t (2004) (6) : 1120-1121
KANTAM, ML;AZIZ, KHATHIJA;LIKHAR, PRAVIN R; Bi s
(cycl opent adi enyl ) zi rconi um di chl ori de f or al kyl at i on
o f h et er o ar o mat i cs an d syn t h esi s o f b i s(i n d o l yl )
met hanes
KANTAM, ML;NEEREJA, V;KAVITA, B;HARITHA, Y; Cu(acac)
(2) immobilized in ionic liquids: A novel and recyclable
cat al yt i c syst em f o r azi r i d i n at i o n o f o l ef i n s u si n g
PhI=NTs as nit rene donor
Synlet t (2004) (3) : 525-527
KANTAM, ML;NEELIMA, B;REDDY, CV;CHAUDHURI,
MK;DEHURY, SK; VO(acac)(2) supp or t ed on t i t ani a: a
het erogeneous prot ocol for t he sel ect i ve oxi dat i on of
sulfides using TBHP
KANTI, P;SRIGOWRI, K;MADHURI, J;SMITHA, B;SRIDHAR,
S; Dehydrat i on of et hanol t hrough bl end membranes
of chit osan and sodium alginat e by pervaporat ion
Separat ion and Purificat ion Technology (2004) 40(3) :
259-266
KAMAL, A;REDDY, K SRINIVASA;PRASAD, B RAJENDRA;
HARI BABU, A; VENKATA RAMANA, A; Mi cr o w ave
enhanced reduct i on of ni t ro and azi do arenes t o N-
aryl formami des empl oyi ng Zn-HCOONH
4
: synt hesi s of
4(3H)-quinazolinones and pyrrolo[2,1-c][1,4] benzodia-
zepi nes
AMAL, A;SANDBHOR, MAHENDRA;ALI SHAIK, AHMAD;
Chemoenzymat ic synt hesis of (S) and ( R )-propranolol
an d so t al o l emp l o yi n g o n e- p o t l i p ase r eso l u t i o n
prot ocol
14(17) : 4581-4583
KAMAL, A;SRINIVAS, O;RAMULU, P;RAMESH, G;KUMAR, P
PRAVEEN; Syn t h esi s o f C8- l i n k ed p yr r o l o [ 2,1-
c] [ 1,4] b enzodi azep i ne-acr i done/ acr i di ne hyb r i ds as
pot ent ial DNA-binding agent s
14(15) : 4107-4111
KAMAL, A;SRINIVAS, O;RAMULU, P;RAMESH, G;KUMAR, P
PRAVEEN; KUMAR, M SHIVA; Synt hesis and DNA binding
af f i ni t y of novel A-C
8
/ C-C
2
-exo unsat urat ed al koxyami
do- linked pyrrolo[2,1-c][1,4]benzodiazepine dimmers
Bioorganic and Medicinal Chemist ry (2004) 12(16) ;
4337-4350
KAMAL, A; REDDY, K LAXMA;DEVAIAH, V; SHANKARAIAH,
N; Faci l e and ef f i ci ent sol i d-phase synt hesi s of DNA-
Int eract i ve pyrrol o[2,1-c][1,4] benzodi azepi nes
Synlet t (2004) (10) : 1841-1843
KAMAL, A;REDDY, K LAXMA;DEVAIAH, V;SHANKARAIAH,
N; Synt hesi s of DNA-i nt er act i ve p yr r ol o[ 2,1-c] [ 1,4]
b enzodi azep i nes b y emp l oyi ng p ol ymer-sup p ort ed
reagent s:
Preparat ion of DC-81 - Synlet t (2004) (14) : 2533-
2536
KAMAL, A;REDDY, K LAXMA;DEVAIAH, V;SHANKARAIAH,
N;REDDY, Y NARASIMHA; A; new approach for t he solid-
phase synt hesi s of pyrrol o[2,1-c][1,4]benzodi azepi nes
involving reduct ive cleavage
181
KARMALI, PRIYA P; KUMAR, VALLURIPALLI V;CHAUDHURI,
ARABINDA ; Design, synt heses and in vit ro gene delivery
efficacies of novel mono-, di- and t rilysinat ed cat ionic
lipids: a st ruct ure-act ivit y invest igat ion
Journal of Medicinal Chemist ry (2004) 47(8) : 2123-
2132
KIRUMAKKI, SHARATH R;NAGARAJU, N;CHARY,
KOMANDUR, VR; NARAYANAN, SANKARASUBBIER;
A facile O-alkylat ion of 2-napht hol over zeolit es H, HY
and HZSM5 using dimet hyl carbonat e and met hanol
KIRUMAKKI, SHARATH R;NAGARAJU, N;NARAYANAN,
SANKARASUBBIER; A comp ar at i ve est er i f i cat i on of
benzyl alcohol wit h acet ic acid over zeolit es H, HY and
HZSM5
Applied Cat alysis A: General (2004) 273(1-2) : 1-9
KRISHNA, GP;REDDY, RS;RAGHUNATH, P;BHANU
PRAKASH, K;KANTAM, ML; CHOUDARY, BM; A
co mp u t at i o n al st u d y o f l i g an d i n t er act i o n s w i t h
hafnium and zirconium met al complexes in t he liquid-
liquid ext ract ion process
Journal of Physical Chemist ry B. 108(19) : 6112-6120
KRISHNAIAH, P; REDDY, VLN; VENKATARAMANA,
G; RAVINDER, K; SRINIVASULU, M;RAJU, TV;RAVIKUMAR,
K; CHANDRASEKAR, D;RAMAKRISHNA, S; VENKATES
WARLU ET AL. New Lammel l ar i n al kal oi ds f r om t he
In d i an Asci d i an Di d em n u m ob scu r u m an d t h ei r
ant i oxi dant propert i es
Journal of Nat ural Product s (2004) 67(7) : 1168-1171
KRISHNA MOHAN, KVV;NARENDER, N;SRINIVASU,
P;KULKARNI, SJ;RAGHAVAN, KV; Novel b r omi nat i on
met hod for anilines and anisoles using NH 4Br/ H
2
O
2
in
CH
3
COOH
KRISHNA MOHAN, KVV;NARENDER, N;KULKARNI, SJ;
Si mpl e and regi osel ect i ve oxyi odi nat i on of aromat i c
compounds wit h ammonium iodide and Oxone

KRISHNAVENI, NS;SURENDRA, K;NARENDER,
M;NAGESWAR, YVD;RAO, KR; Hi g h l y ef f i ci en t
r eg i osel ect i ve r i n g op en i n g of azi r i d i n es t o b et a-
haloamines in t he presence of bet a-cyclodext rin in wat er
KRISHNAVENI, NS;SURENDRA, K;RAO, KR; A si mpl e and
hi ghl y sel ect i ve bi omi met i c oxi dat i on of al cohol s and
epoxides wit h N-bromosuccinimide in t he presence of
bet a-cyclodext rin in wat er
Advanced Synt hesis & Cat alysis (2004) 346(2-3) :346-
350
KRISHNAVENI, NS; SURENDRA, K; REDDY, MS; NAGESWAR,
YVD; RAO, KR; Synt hesi s of t hi ranes f rom oxi ranes i n
t he presence of bet a-cyclodext rin in wat er
397
KULKARNI, SJ;KRISHNA MOHAN, KVV;RADHA RANI,
V;NARENDER, N;RAGHAVAN, KV; Syn t h esi s o f
h et er o cycl i c t h r ee- f u sed r i n g co mp o u n d s u si n g
molecular sieve cat alyst s
St udies in Surface Science and Cat alyst s (2004) 154 C
: 2781-2787
KULKARNI, SJ;SRINIVASU, P;RAGHAVAN, KV; Fast and
efficient synt hesis of zeolit es under high pressure
St udi es i n Surf ace Sci ence and Cat al ysi s (2004)
154 A : 184-188
KULSHRESTHA, UC;RAO, T NAGESWARA;AZHAGUVEL, S;
KULSHRESTHA, MJ; Emi ssi ons and accumul at i on of
met als in t he at mospheres due t o crackers and sparkles
during Diwali fest ival in India
At mospheric Environment (2004) 38(27) : 4421-4425
KUMAR, D NAVEEN;RAO, B VENKATESWARA; Asymmet ric
syn t h esi s of (1R,1 R,5 R,7 R) an d (1S,1 R,5 R,7 R)-1-
hydroxy-exo-brevicomin and a formal synt hesis of (+)-
exo-brevi comi n
Publications
182
KUMAR POTLURI, SRINAGESH;RAGHU RAMULU,
A;PARDHASARADHI, M; Synt hesis of new unsymmet rical
opt ically act ive (s)-(+)-naproxen dendrimers
Tet rahedron (2004) 60(48) : 10915-10920
KUMAR, V SIVA;NAGARAJA, BM;SHASHIKALA, V; SEETHA
RAMULU, P;PADMASRI, AH;RAJU, B DAVID;RAO, KS RAMA;
Role of acidic and basic sit es of Al
2
O
3
in predict ing t he
react i on pat hway of i sophorone t ransf ormat i on
223(1-2) : 283-288
KUMAR, V SIVA; NAGARAJA, BM; SHASHIKALA, V; PADMASRI, AH;
MADHAVENDRA, S SHAKUNTALA;RAJU, B DAVID;RAO, KS RAMA
Highly efficient Ag/ C cat alyst prepared by elect ro-chemical
deposit ion met hod in cont rolling microorganisms in wat er
Journal of Molecular Catalysis A: Chemical (2004) 223(1-2) :
313-319
KUMARA SWAMI, G;NIVEDITA, J;SASTRY, MNV;ASHOK
KUMAR, B; An expedit ions, pract ical large scale synt hesis
of 4-amino-2-chloro-6,7-dimet hoxyquinazoline
(2004) 36(4) : 341-345
LINGAIAH, BPV;REDDY, G VENKAT;YAKAIAH, T;NARSAIAH,
B;REDDY, SN;YADLA, R;RAO, P SHANTHAN Efficient and
co n ven i en t met h o d f o r t h e syn t h esi s o f p o l y
funct ionalised 4H-Pyrans
LUCKE, B;NARAYANA, KV;MARTIN, A;JAHNISCH, K;
Oxidat ion and ammoxidat ion of aromat ics
1407-1424
MADHAVI, G;KULKARNI, SJ;RAGHAVAN, KV; Si de-chai n
al kyl at i on of het erocycl i c compounds over modi f i ed
zeol i t es
Journal of Molecular Cat alysis A: Chemical (2004) 154
C : 2760-2766
MAHBOOB, M;SIDDIQUI, MKJ; Ef f ect s o f a n o vel
organophosphorus pest icide (RPV-V) on eut ra hepat ic
det oxifying enzymes aft er repeat ed oral doses in rat s
Toxicology (2004) 202 : 159-164
KUMAR, D NAVEEN;RAO, B VENKATESWARA; A chi r on
approach t o (1R,2R,5S,7R)-2-hydroxy-exo-brevicomin, a
comp onent of t he vol at i l es p r od uced b y t he mal e
mount ain pine beet le, Dendroct onus ponderosae
KUMAR, HMS;RAO, M SHESHA;CHAKRAVARTHY, P
PAWAN;YADAV, JS; En zymat i c r eso l u t i o n o f N-
aryl azi ri di ne carboxyl at es
KUMAR, HMS;CHAKRAVARTHY, P PAWAN; RAO, M
SHESHA; JOYASAWAL, SIPAK;YADAV, JS; Sol i d p hase
synt hesi s of hyd r oxy b enzot hi azep i nones t hr oug h
cycl at i ve rel ease under t hermol ysi s.
KUMAR, K KOTHAKONDA;BOSE, DS; Synt hesis of a novel
t et rahydroisoquinolino[2,1-c][1,4] benzodiazepine ring
syst em wit h DNA recognit ion pot ent ial
14(17) : 4371-4373
KUMAR, K KOTHAKONDA;BOSE, DS; Th e f i r st
en an t i o mer i cal l y p u r e syn t h esi s o f (S)- an d ( R )-
Naft opidil ut ilizing hydrolyt ic kinet ic resolut ion of (+)-
(a-Napht hyl) Glycidyl et her
KUMAR, MK; PRABHAKAR, S; KUMAR, MR; REDDY,
TJ; PREMSINGH, S; RAJAGOPAL, S; VAIRAMANI, M;
Coordinat ion chemist ry of chromium-Salen complexes
st udi ed by el ect rospray i oni zat i on mass spect romet ry
Rapid Communicat ions in Mass Spect romet ry: RCM
(2004)18(10) : 1103-1108
KUMAR, M RAVI;PRABHAKAR, S;KUMAR, M KIRAN;REDDY,
T; JAGADESHWAR;VAIRAMANI, M; Neg at i ve i o n
el ect r o sp r ay i o n i zat i o n mass sp ecr al st u d y o f
dicarboxylic acids in t he presence of halide ions
(2004)18(10) : 1109-1115
KUMAR POTLURI, SRINAGESH;RAGHU RAMULU, A;
PARDHA SARADHI, M; Synt hesis of new unsymmet rical
pol yaryl est er dendri mers
Tet rahedron (2004) 60(17) : 3739-3744
183
MAHESH, M;VENKATESHWAR REDDY, Ch;SRINIVASA
REDDY, K;RAJU, PVK; NARAYANA REDDY, VV; Imino Diels-
Al d er r eact i o n s: Ef f i ci en t syn t h esi s o f p yr an o an d
furoquinolines cat alyzed by ZrCl
4
MAHIDHAR, YENUGONDA VENKATA;RAJESH,
MUKTHAVARAM;CHAUDHURI, ARABINDA Spacer-arm
modul at ed gene del i very ef f i cacy of novel cat i oni c
glycolipids: design, synt hesis, and in vit ro t ransfect ion
bi ol ogy
3948
MAHIDHAR, YENUGONDA VENKATA; RAJESH, MUKTHA VARAM;
MADHAVENDRA, SS;CHADHURI, ARABINDA; Dist ance of hydroxyl
f unct i onal i t y f rom t he quat erni zed cent er i nf l uence DNA
binding and in vit ro gene delivery efficacies of cat ionic lipids
wit h hydroxyalkyl headgroups
5728
MAJETI, BHARAT KUMAR; SINGH, RAJKUMAR SUNIL; YADAV,
SUDHEER KUMAR; BATHULA, SURENDAR REDDY;RAMAKRISHNA,
SISTLA; DIWAN, PV; MADHA VENDRA, SURKARA SAKUNTHALA;
CHAUDHURI, ARABINDA; Enhanced i nt ravenous t ransgene
expression in mouse lung using cyclic-head cat ionic lipids
Chemist ry & Biology (2004) 11(4) : 427-437
MANJULA, A;RAO, BV;NEELAKANTAN, P; An inexpensive
prot ocol for Biginelli react ion
MEREYALA, HB;BASEERUDDIN, MOHD;REDDY K
SREENIVASULU; For mal synt hesi s of f ur anodi ct i ne B
from D-glucose
MEREYALA, HB;FATIMA, LIYAKAT; PALLAVI, POLA;
Resol ut i on of 1-aryl al kyl ami nes wi t h 6-(1,2:3,4-di -O-
isopropylidene- galact opyranosyl) hydrogen pht halat e
MEREYALA, HB;MAMIDYALA, SREEMAN KUMAR; Simple
ent r y i nt o i sonucl eosi d es: synt hesi s of 6-ami no-9-
[ ( 3 S, 4 S, 5 R) - 4 - h y d r o x y - 5 - ( h y d r o x y m e t h y l )
t et rahydrof uran-3-yl ] puri ne
MEREYALA, HB;MAMIDYALA, SREEMAN KUMAR; The
syn t h esi s o f [ ([ b et a- D- r i b o f u r an o syl o xy) met h yl ]
nucleosides Nucleosides,
Nucleaot ides & Nucleic Acids, (2004) 23(4) : 655-669
MEREYALA, HB;BHAVANI, S;RUDRADAS, AP; Di r ect i ng
ef f ect of axi al and equat ori al anomeri c subst i t uent i n
sit e specific glycosylat ion of glucopyranosides
MEREYALA, HARI BABU; POLA, PALLAVI; Con t r ol l ed
Acet ol ysi s of 3,6-Anhydro-5-O-benzyl -1,2-O-i sopropy
lidene-a-D-glucofuranose: Synt hesis of 1-(3',6'-Anhydro-
a-D-gl ucof uranosyl )t hymi ne
MESHRAM HM;PREMALATHA K;RAMESHBABU K;
EESHWARAIAH B;YADAV JS; Zi r coni um(IV) chl or i d e
cat alyzed cyclizat ion of ort ho-allylphenols: Synt hesis of
2-met hyl -2,3-di hydrobenzof urans
Synt het ic Communicat ions (2004) (17) : 3091-3097
MIRZA, SHAMA PARVEEN;RAJU, N PRASADA;
MADHAVENDRA, SS;VAIRAMANI, M ; 5-Ami n o -2-
mercapt o-1,3,4-t hiadizole: a new mat rix for t he efficient
mat ri x-assi st ed l aser desorpt i on/ i oni zat i on of neut ral
carbohydrat es
(2004) 18(14) : 1666-1674
MIRZA, SHAMA PARVEEN;RAJU, N PRASADA;VAIRAMANI,
M ; Est i mat i on of t he prot on af f i ni t y val ues of f i f t een
mat r i x-assi st ed l aser desor p t i on/ i oni zai on mat r i ces
und er el ect r osp r ay i noi zai on cond i t i ons usi ng t he
ki net i c met hod
Jour nal of t he Amer i can Soci et y f or Mass
Spect romet ry (2004) 15(3) : 431-435
Publications
184
MURTHY, J KRISHNA;CHANDRA SHEKAR, S; RAO, KS
RAMA;KISHAN, G;NIEMANTSVERDRIET, JW; Advant ages
of FCCA and Bi promot i on i n Bi -Pd/ FCCA cat al yst s for
t he hydrodechlorinat ion of CCl
2
F
2
MURTHY, J KRISHNA;CHANDRA SHEKAR, S;PADMASRI,
AH;VENUGOPAL, A; SIVA KUMAR, V;NAGARAJA,
BM;SHASHIKALA, V;RAJU, B DAVID;RAO, P KANTA; RAO,
KS RAMA; Promot ional effect of magnesia addit ion t o
act i ve car b o n su p p o r t ed Pd cat al yst o n t h e
char act er i st i cs and hyd r od echl or i nat i on act i vi t y of
CCl
2
F
2
MURTY, US;PRAVEEN, B;SATYA KUMAR, DVR;SRIRAM,
K;RAO, K MADHUSUDHAN;SAI, KSK; A baseline st udy of
rural Bancroft ian filariasis in sout hern India
Sout heast Asian Journal of Tropical Medicine and
Public Healt h (2004) 35(3) : 583-586
NAGARAJA, BM;KUMAR, V SIVA;SHASHIKALA,
V;PADMASRI, AH;REDDY, S SREEVARDHAN;RAJU, B
DAVID;RAO, KS RAMA; Effect of met hod of preparat ion
o f co p p er mag n esi u m o xi d e cat al yst o n t h e
dehydrogenat i on of cycl ohexanol
223(1-2) : 339-345
NAGAVENI, V;PRABHAKAR, S;VAIRAMANI, M;
Di f f er en t i at i o n o f Un d er i vat i zed d i ast er eo mer i c
hexosamine monosaccharides and t heir quant ificat ion
i n a mi xt u r e u si n g t h e ki n et i c met h o d u n d er
el ect rospray i oni zat i on condi t i ons
Analyt ical Chemist ry (2004) 76(13) : 3505-3509
NARASHIMAMURTHY, J;RAM RAO, AR;SASTRY, GN;
Aromat ase inhibit ors: A new paradigm in breast cancer
t reat ment
Current Medicinal Chemisty Anti-Cancer Agents (2004)
4(6) : 523-534
MOHAN, SV;BHASKAR, YV;KARTHIKEYAN, J; Bi ol ogi cal
decolourisat ion of simulat ed azo dye in aqueous phase
by algae Spirogyra species
Int ernat ional Journal of Environment and Pollut ion
(2004) 21(3) : 211-222
MOHAN, SV;SIRISHA, K;RAO, N CHANDRA SEKHARA;
SARMA, PN;REDDY, S JAYARAMA Deg r ad at i o n o f
chl orp yri f os cont ami nat ed soi l b y b i osl urry react or
o p er at ed i n seq u en ci n g b at ch mo d e: b i o p r o cess
moni t ori ng
Journal of Hazardous Mat erials (2004) 116(1-2) : 39-
48
MOHAN, SV;KARTHIKEYAN, J; Adsor pt i ve removal of
react ive azo dye an aqueous phase ont o charfines and
act i vat ed carbon
Clean Technological Environ Policy (2004) 6 : 196-200
MOULI, PC;KUMAR, MP;REDDY, S JAYARAMA;MOHAN, SV;
Monit oring of air pollut ion in Indian met ropolit an cit ies:
Modelling and qualit y indexing
Int ernat ional Journal of Environment and Pollut ion
(2004) 21(4) : 365-382
MOULI, PC;MOHAN, SV;REDDY, S JAYARAMA;
El ect r och emi cal p r ocesses f or t h e r emed i at i on of
w ast ew at er an d co n t ami n at ed so i l : Emer g i n g
t echnol ogy
Journal of Scient ific and Indust rial Research (2004)
63(1) : 11-19
MURTHY, BSN;RAO, R NAGESWARA; Global opt imizat ion
f or predi ct i on of bl end composi t i on of gasol i nes of
desired oct ane number and propert ies
Fuel Processing Technology (2004) 85(14) : 1595-1602
MURTHY, J KRISHNA;CHANDRA SHEKAR, S;KUMAR, V
SIVA;RAJU, B DAVID; SREEDHAR, B;SAI PRASAD, PS;RAO,
P KANTA;RAO, KS RAMA;BERRY, FJ;SMART, LE Ef f ect of
t u n g st en ad d i t i o n t o Pd / Zr O
2
syst em i n t h e
hydrodechlorinat ion act ivit y of CCl
2
F
2
223(1-2) : 347-351
185
NARAYANA, KV;RAJU, B DAVID;KHAJA MASTHAN, S;RAO,
V VENKAT;RAO, P KANTA;SUBRAHMANIAN, R;MARTIN, A;
ESR sp ect r o sco p i c ch ar act er i zat i o n o f V2O
5
/ Al F
3
ammoxi dat i on cat al yt s
NARAYANA, KV;RAJU, B DAVID;KHAJA MASTHAN, S;RAO,
V VENKAT;RAO, P KANTA; MARTIN, A; Ceri um f l uori de
su p p o r t ed V
2
O
5
cat al yst s: p hysi co - ch emi cal
charact erizat ion and 3-picoline ammoxidat ion act ivit y
223(1-2) : 321-328
NARENDAR, M;REDDY, M SOMI;RAO, K RAMA; A mild and
efficient oxidat ive deprot ect ion of THP et hers wit h NBS
in t he presence of b-cyclodext rin in wat er
NARENDER, M;SURENDRA, K;KRISHNAVENI, NS;REDDY, M
SOMI;RAO, K. RAMA; A facile regioselect ive ring opening
of aziridines t o haloamines using t et rabut ylammonium
hal i d es i n t he p r esence of -cycl od ext r i n i n wat er
NARENDER, N;KRISHNA MOHAN, KVV;SRINIVASU,
P;KULKARNI, SJ;RAGHAVAN, KV; A simple, efficient and
regioselect ive oxychlorinat ion of aromat ic compounds
using ammonium chloride and oxone
Indian Journal of Chemist ry Sect ion B (2004) 43 (6) :
1335-1338
NARENDAR, P;GANGADASU, B;RAMESH, C;RAJU B
CHINNA;RAO, VJ; Faci l e an d sel ect i ve synt h esi s of
ch l or omet h yl p yr i d i n es an d ch l or op yr i d i n es u si n g
di phosgene/ t ri phosgene
NISHA, CK; MANORAMA, SV; GANGULI, M; MAITI, SOUVIK;
KIZHAKKEDATHU, JAYACHANDRAN N ; Compl exes of
pol y(et hyl ene gl ycol )-based cat i oni c random copol y
mer and cal f t hymus DNA: A comp l et e b i op hysi cal
charact eri zat i on
Langmuir (2004) 20(6) : 2386-2396
NISHA, CK;MANORAMA, SV;KIZHAKKEDATHU, JAYA
CHANDRAN N; MAITI, SOUVIK; Wat er-Soluble Complexes
f r om Rand om Cop ol ymer and Op p osi t el y Char ged
Surfact ant . 2. Complexes of Poly(et hylene glycol)-based
cat ionic random Copolymer and Bile Salt s
Langmuir: (2004) 20(20) : 8468-8475
NISHA, CK; MANORAMA, SV; MAITI, S; JAYACHANDRAN,
KN; ASWAL, VK; GOYAL, PS; Smal l - an g l e n eu t r on
scat t ering st udies on wat er soluble complexes of poly
(et hyl ene gl ycol )-based cat i oni c random copol ymer
and SDS - Pramana
Journal of Physics (2004) 63(2) : 315-320
NIVASU, M VENKATA;REDDY, THIMMA T;TAMMISHETTI, S;
In si t u pol ymeri zabl e pol yet hyl enegl ycol cont ai ni ng
pol yest erpol yol acryl at es for t i ssue seal ant appl i cant s
Biomat erials (2004) 25(16) : 3283-3291
NIVASU, M VENKATA;REDDY, THIMMA T;TAMMISHETTI, S;
In sit u polymerizable polyest er polyols for t issue sealant
applicat ions : Effect of choice of acid and diol on sealant
propert i es
Trends in Biomat erials and Art ificial Organs (2004)
18(1) : 52-59
NIVASU, M VENKATA;YARAPATHI, V REDDY;TAMMISHETTI,
S; Synt hesis, UV phot o-polymerizat ion and degradat ion
st udy of PEG cont aining polyest er polyol acrylat es
Polymers for Advanced Technologies (2004) 15(3)
128-133
NOORJAHAN, M;DURGA KUMARI, V;SUBRAHMANYAM,
M;BOULE, P ; A novel and efficient phot ocat alyst : TiO2-
HZSM-5 combinat e t hin film
209-213
PADMASRI, AH;VENUGOPAL, A;KUMAR, V SIVA;
SHASHIKALA, V;NAGARAJA, BM; SEETHARAMULU, P;
SREEDHAR, B;RAJU, B DAVID;RAO, P KANTA;RAO, KS
RAMA; Rol e of hydrot al ci t e precursors as support s for
Pd cat alyst s in hydrodechlorinat ion of CCl
2
F
2
223(1-2) : 329-337
Publications
186
PRASAD, TEV;ASWIN RAJ, ED;MAHENDER, G;REDDY, M
SAINATH;KUMAR, V SENHIL;SATISH GARAPATI;
PANTANJALI, V;PRASAD, DHL; Bu b b l e t emp er at u r e
Measurement s on some Bi nary Mi xt ures f ormed b y
t et rahydrofuran or Amylalcohol wit h Hydrocarbons or
Chlorohydrocarbons or But anols at 94.6 or 05.8 kPa
Journal of Chemical and Engineering Data (2004) 49(4) : 746-
749
PRASAD, TEV;BANERJEE, S;KISHORE BABU, J;PRASAD,
DHL; Boiling t emperat ure measurement s on t he binary
mi xt ures f ormed b y di met hyl carb onat e wi t h some
chl oroet hanes and chl oroet hyl enes at 95.8 kPa Fl ui d
Phase Equilibria (2004) 218(2) : 291-293
PRASAD, TEV;HARITHA, M;GEETHA, NB;PAVAN KUMAR,
YP;PRASAD, DHL; Bubbl e Temperat ure Measurement s
on t he Binary Mixt ures of Chlorobenzene wit h Met hanol,
n-propanol and sec-But anol at 94.6 kPa
Physics and Chemist ry of Liquids (2004) 42(4) : 385-
389
PRASAD, TEV; KUMAR, SS; GOUD, MBP; KUMAR, PA;
SRINIVAS, A; REDDY, PS; PRASAD, DHL; Errat um: Bubble
t emperat ure measurement s on binary mixt ures formed
by cycl ohexane at 94.7 kPa (Journal of Chemi cal and
Engineering Dat a (2003) 48 (351-353))
: 740
PRASAD, TEV; PATANJALI, V; SUDHAKAR, TA; RADHIKA,
BS;ARVIND, VM;PRASA, DHL; Bu b b l e t emp er at u r e
measurement s on t he binary mixt ures of n-hept ane or
n i t r o b en zen e o r ch l o r o b en zen e w i t h so me
chloroet hanes and chloroet hylenes at (94.6 t o 95.8) kPa
: 199-201
PRASAD, TEV;PRASAD, DHL;KALPANA, T; Bu b b l e
t emp er at u r es o f t h e b i n ar y mi xt u r es o f 1,2-
d i met h yl b en zen e w i t h 2- p r o p an o l , 1- b u t an o l , 2-
p r op an ol , 1-b u t an ol , 2-met h yl p r op an e-1-ol an d 2
met hypropane-2-ol at 95K Pa
Chemi cal Engi neer i ng Communi cat i ons ( 2 0 0 4 )
191(1) : 17-26
PALANIAPPAN, S; Benzoyl peroxi de oxi dat i on rout e t o
polyaniline salt s Part I
Polymers for Advanced Technologies (2004) 15(3)
111-117
PALANIAPPAN, SRINIVASAN;CHANDRA SHEKAR,
RAMPALLY; Synt hesis of 7-hydroxy-4-met hyl coumarin
using polyaniline support ed acid cat alyst
209(1-2) : 117-124
PALANIAPPAN, SRINIVASAN;CHANDRA SHEKAR,
RAMPALLY; Tr an sest er i f i cat i o n o f ket o est er s w i t h
alcohols using polyaniline salt s as cat alyst s
140-143
PALANIAPPAN, SRINIVASAN; JOHN, AMALRAJ; AMAR
NATH, CHELLACHAMY ANBALAGAN;RAO, V JAYA
THIRTHA; Man n i ch - t yp e r eact i o n i n so l ven t f r ee
condit ion using reusable polyaniline cat alyst
218(1) : 47-53
PALANIAPPAN, SRINIVASAN;SARAVARAN, C;AMARNATH,
CHELLACHAMY ANBALAGAN;RAO, V JAYATHIRTHA;
Polyaniline salt s and complexes as cat alyst in bisindole
synt hesi s
PALANIAKUMAR, M;VAIRAMANI, M;PRASADA RAJU,
N;LOBO, CHARMAINE; ANBUMANI, N;GIRISH KUMAR,
CP;MENON, THANGAM;SHANMUGASUNDARAM, S; Rapid
d i scr i mi nat i on b et ween st r ai ns of b et a haemol yt i c
st rept ococci by Cell mass spect romet ry
Indian Journal Medical Research (2004) 119(6) : 283-
288
PANDA, SIVA SANKAR;CHATTOPADHYAY;RAJU, KVSN;
Roof cool i ng mat er i al s and coat i ngs: An Emer gi ng
Technol ogy
Paint india (2004) : 65-74
PRABHAKAR, S; RADHA KISHAN, M; MIRZA, SP; RAGHA
VAN, KV; VAIRAMANI, M; Mass spect ral st udy of meso-
alkyl and meso-cycloalkyl calix(4) pyrroles under lect ron
i mpact condi t i ons
18(18) : 2077-2086
187
PRASAD, TEV;PRASAD, DHL;KISHORE BABU, J;BANERGEE,
S; Bubbl e Temperat ure Measurement s on t he Bi nar y
mi xt ures formed by 1,2-Di met hyl -benzene wi t h some
Chloroet hanes and Chloroet hylenes at 95.8 kPa
Chemi cal Engi neer i ng Communi cat i ons ( 2 0 0 4 )
191(10) : 1323-1328
PRASAD, TEV;PRASAD, DHL;NAVEEN, PG;KUMAR, B
SANTOSH; Bubble t emperat ure measurement s on t he
binary mixt ures of 1,4-Dimet hyl-benzene wit h iso-,sec-
and t ert -Buranols at 95 kPa:
Chemical Engineering Communications (2004) 191(7)
: 998-1002
PRASAD, TEV;RAVI PRASHANTH, P;KUMAR, D
SURESH;PRASAD, DHL; Bu b b l e t emp er at u r e
measur ement s on t he b i nar y mi xt ur es of Di met hyl
carbonat e wit h some Alcohols at 95.8 kPa
Journal of Chemical and Engineering Dat a (2004)
49(4) : 744-745
PREMSINGH, S;VENKATARAMANAN, NS;RAJAGOPAL,
S;MIRZA, SP;VAIRAMANI, M; El ect ron Transfer react i on
of Oxo(salen)chromium(V) ion wit h anilines
Inorganic Chemist ry (2004) 43(18) : 5744-5753
PRIYAKUMAR, UD;PUNNAGAI, M;KRISHNA MOHAN,
GP;SASTRY, G NARAHARI; A comput at i onal st ud y of
cat ion-int eract ions in polycyclic syst ems: exploring t he
dependence on t he curvat ure and elect ronic fact ors
Tet rahedron (2004) 60(13) : 3037-3043
PRIYAKUMAR, UD;REDDY, AS;SASTRY, G NARAHARI; The
design of molecules cont aining planar t et racoordinat e
carbon
PRIYAKUMAR, UD;SASTRY, G NARAHARI; Desi g n of
neut ral hydrocarbons having a planar t et racoordinat e
carbon
Indian Journal of Chemist ry Sect ion A-Inorganic Bio-
Inorganic Physical Theoretical & Analytical Chemistry
(2004) 43(3) : 455-457
PRIYAKUMAR, UD;SASTRY, G NARAHARI; A syst em wit h
t hree cont i guous pl anar t et racoordi nat e carbons i s
viable: a comput at ional st udy on a C6H62=isomer
PRIYAKUMAR, UD;PUNNAGAI, M;SASTRY, G NARAHARI;
Faci l e val en ce i so mer i zat i o n amo n g b i s(si l acycl o
propenyl), disila(Dewar benzene) and disilabenzvalene
Journal of Organomet allic Chemist ry (2004) 689(7) :
1284-1287
PRIYAKUMAR, UD;SASTRY, G NARAHARI; C21H9Z (Z=-3
t o +3): a t heoret ical st udy on t he redox behaviour of C3
symmet ric fragment of C60
674(1-3) : 69-75
PRIYAKUMAR, UD;SASTRY, G NARAHARI;MEHTA,
GOVERDHAN; Devel opment of predi ct i ve model s of -
facial select ivit y; a crit ical st udy of nucleophilic Addit ion
t o st eri cal l y unbi ased ket ones
Tet rahedron (2004) 60(15) : 3465-3472
PUNNAGAI, M;DINADAYALANE, TC;SASTRN, G
NARAHARI; Densi t y f unct i onal t heory st udy of t he Di el s-
Al der react i vi t i es of [ b] -annel at ed cycl i c f i ve-membered
d i en es
Journal of Physical Organic Chemist ry (2004) 17(2) :
152-161
PUNNAGAI, M;JOSEPH, S;SASTRY, GN; A t heoret ical st udy
of porphyrin isomers and t heir core-modified analogues:
Ci s- t r an s i so mer i sm, t au t o mer i sm an d r el at i ve
st abi l i t i es
PUNNAGAI, M;SASTRY, G NARAHARI; Theoret ical st udy
on t he st ruct ure and st abilit y of ring invert ed porphyrin
i somers
Journal of Molecular St ruct ure THEOCHEM (2004)
684(1-3) : 21-28
Publications
188
RADHA KRISHNA, P;KRISHNA RAO, LOPINTI;KANNAN,
V; Di ast ereosel ect i ve Bayl i sHi l l man react i on: fi rst use
of chiral 2,3-epoxy aldehydes as novel elect rophiles
RADHAKRISHNA, PALAKODETY; NARSINGAM,M;
KANNAN, V; Use of a Bayl i sHi l l man ad d uct i n t he
st er eo sel ect i ve syn t h esi s o f syr i b u t i n s vi a a RCM
prot ocol
RADHA KRISHNA, PALAKODETY;SEKHAR, ER;KANNAN, V;
N-met hyl morphol i ne and urot ropi ne as usef ul base
cat alyst s in Baylis-Hillman react ion
RADHA KRISHNA, P;GOVARDHAN REDDY, Ch;SHARMA,
GVM; Yb(Ot f )3 and ZrCl 4 medi at ed rearrangement of
alkoxybenzyl allyl et hers int o aldehydes
Let t ers in Organic Chemist ry (2004) 1(3) : 212-214
RADHA KRISHNA, P; RACHNA, SACHWANI; KANNAN,
V; Double asymmet ric induct ion as a novel t ool for high
st ereocont rol in Baylis-Hillman react ion
(2004) (22) : 2580-2581
RADHA KRISHNA, P;RAMANA REDDY, VV;SHARMA, GVM;
Fl exi b l e an d si mp l e r o u t e f o r t h e st er eo sel ect i ve
syn t h esi s of t r i sub st i t ut ed g -b ut yr ol act on es: Tot al
synt hesis of (+)-Blast omycinone and it s analogs
Synt hesis-St ut t gart (2004) (13): 2107-2114
RAGHAVAN, SADAGOPAN;KUMAR, Ch NAVEEN;TONY,
KA;REDDY, S RAMAKRISHNA;RAVI KUMAR, K; Regio-and
st ereoselect ive t ransfer of p-t oluenesulfonamido group
f rom sul phur t o carbon: preparat i on of ami noal cohol
deri vat i ves from al l yl al cohol s
Tet rahedron Let t ers, (2004) 45(39) : 7231-7234
RAGHAVAN, SADAGOPAN;RAJENDER, A; St ereoselect ive
synt hesi s of (-)-al l osedami ne
RACHEL, A;DURGA KUMARI, V;SUBRAMANIAN, R;CHARY,
KVR;RAO, PK ; A st udy of t he st ruct ural-charact erizat ion
and cycl ohexanol d ehyd r ogenat i on act i vi t y of CU/
GAMMA-AL
2
0
3
cat alyst s -
I ndian Journal of Chemist ry Sect ion A I norganic
Bioinorganic Physical Theoret ical and Analyt ical
Chemist ry (2004) 43(6) : 1172-1180
RADHAKRISHNA, M;RAO, C KAMESWARA; Axial vibrat ion
of U-shaped bel l ows wi t h el ast i cal l y rest rai ned end
condi t i ons
Thin Walled St ruct ures (2004) 42(3) : 415-426
RADHA KISHAN, M;RADHA RANI, V;MURTY, MRVS;SITA
DEVI, P;KULKARNI, SJ;RAGHAVAN, KV; Syn t h esi s of
cal i xp yr r ol es and p or p hyr i ns over mol ecul ar si eve
cat al yst s
223(1-2) : 263-267
RADHAKRISHNA, PALAKODETY;KANNAN, V;REDDY, PVN;
N-met hylprolinol cat alysed asymmet ric Baylis-Hillman
react i on
Advanced Synthesis and Catalysis (2004) 346(6) : 603-606
RADHAKRISHNA, PALAKODETY;KANNAN, V;SHARMA,
GVM; FeCl 3 and Yb(Ot f ) (3) medi at ed conversi on of
acet at es of t he Baylis-Hillman adduct s int o (Z) and (E)
t ri subst i t ut ed al kenes
RADHAKRISHNA, PALAKODETY;MANJUVANI, A;KANNAN,
V;SHARMA, GVM; Sul phol ane-A new sol vent f or t he
Baylis-Hillman react ion
RADHAKRISHNA, PALAKODETY;KANNAN, V;SHARMA,
GVM; Fi rst Di ast ereosel ect i ve Int ramol ecul ar Bayl i s-
Hi l l man React i on: An Easy Access t o Chi r al al p ha-
Met hyl ene-bet a-hydroxyl act ones
6467-6469
189
RAGHAVAN, SADAGOPAN;RAJENDER, A; JOSEPH, SUJU
C;RASHEED, M ABDUL;KUMAR, K RAVI; Reg i o - an d
st er eo sel ect i ve syn t h esi s o f 1,3- ami n o al co h o l
der i vat i ves f r om al l yl ami ne der i vat i ves vi a i nt er nal
sul fi nyl group part i ci pat i on
RAGHAVAN, SADAGOPAN;RASHEED, M ABDUL; Modular
and st er eosel ect i ve f or mal synt hesi s of MeBmt , an
u n u su al ami n o aci d co n st i t u en t o f cycl o sp o r i n - A
Tet rahedron (2004) 60(13) : 3059-3065
RAGHAVAN, SADAGOPAN;REDDY, S RAMAKRISHNA;
St ereoselect ive synt hesis of t he enant iomer of t he key
fragment of crocacin
RAGHAVAN, SADAGOPAN;SREEKANTH, T; Novel and
st ereosel ect i ve synt hesi s of (+)-l ent i gi nosi ne
RAGHAVAN, SADAGOPAN;TONY, KA; St er eosel ect i ve
synt hesis of (2R,3R) and 2R,3S)-3-hydroxyleucines
RAGHAVAN, SADAGOPAN;RAJENDER, A ; St ereoselect ive
synt hesis of ()-allosedamine and (1R,3R)-HPA-12 from
-p-t ol uenesul f onami do-,-unsat urat ed sul f oxi de
Tet rahedron (2004) 60(23) : 5059-5067
RAGHLUKUMAR, C;RAGHUKUMAR, S;SHEELU, G;GUPTA,
SM;NATH, BN;RAO, BR; Buri ed i n t i me-cul t urabl e f ungi
i n a deep-sea sedi ment core from t he chagos t rench,
Indian Ocean Deep-Sea Research Part I
Oceanographi c Research Papers (2004) 51(11) :
1759-1768
RAGHUNATH, P; BHANUPRAKASH, K; SRINIVAS,
R; Format ion of Silicon analogues of t hio-isocyanic acid,
HNSiS, and it s isomers by Neut ral-Neut ral react ions of
t he fragment s: A comput at ional st udy
Journal of Physical Chemist ry A (2004) 108(42) :
9218-9225
RAHMAN, MF;MAHBOOB;GROVER, P; In - Vi t r o
acet ylcholinest erase inhibit ion by novel of compounds
in various t issues of t he fish Channa-punct at us
Bul l et i n of Envi r onment al Cont ami nat i on and
Toxicology (2004) 72(1) : 38-44
RAHMAN, MF;MAHBOOB, M;GROVER, P; Comparat ive sensit ivit ies
o f i n vi t r o acet yl ch o l i n est er ase i n h i b i t i o n b y n o vel
organophosphorus compounds in broiler chicken
Toxicol. Internat ional (2004) 11(1) : 49-53
RAHMAN, MF;SIDDIQUI, MKJ; Bi ochemi cal ef f ect s of
vepacide (from Azadiracht a indica) on Wist ar rat s during
subchroni c exposure
Ecot oxi col ogy And Envi ronment al Saf et y (2004)
59(3) : 332-339
RAJU, B DAVID; RAO, KS RAMA;SALVAPATHI, GS;PRASAD,
PS SAI; RAO, P KANTA; Role of Suppor t and Promot er in
t he Select ive Conversion of Isophorone t o 3,5-Xylenol
over Chromi a Cat al yst s
Topics in Cat alysis (2004) 29(3-4) : 167-174
RAJU, B CHINA;NEELAKANTAN, PARVATHI;BHALERAO,
UT ; Qui none met hi de i ni t i at ed cycl i zat i on react i on:
synt hesi s of 4-aryl -1,2,3,4-t et rahydrooi soqui nol i nes
Tet rahedron Let ters (2004) 45(40) :7487-7489
RAJU, B CHINA;NEELAKANTAN, PARVATHI;BHALERAO,
UT; A facile and convenient met hod for t he synt hesis of
ni t ro phenol s and chl oropyri di nol s
RAM, MS;PALANIAPPAN, S; A process for t he preparat ion
of polyaniline salt doped wit h acid and surfact ant groups
using benzoyl peroxide
Journal of Mat erials Science (2004) 39(9) : 3069-3077
RAMARAO, VVVNS;REDDY, G VENKAT;MAITRAIE, D;
RAVIKANTH, S;YADLA, R;NARSAIAH, B;RAO, P SHANTHAN
One-p ot synt hesi s of f l uor i ne cont ai ni ng 3-cyano/
et hoxycarbonyl -2-met hyl -benzo[b]f urans
Tet rahedron (2004) 60(52) : 12231-12237
Publications
190
RANI, GN;AYACHIT, NH;NATH, KR; RAO, VJ; Preparat i on
and charact eri zat i on of Eu3+ dop ed p owder sp i nel
phosphors (MgAl1.8Y0.2-xO4)
Spect r ochi mi ca Act a - Par t A: Mol ecul ar and
Biomolecular Spect roscopy (2004) 60(11) :
RANI, K YAMUNA;PATWARDHAN, SC; Dat a-d r i ven
mod el i ng and op t i mi zat i on of semi -b at ch r eact or s
using Art ificial Neural Net works -
Industrial and Engineering Chemistry Research (2004)
43(23) : 7539-7551
RAO, A GANGAGNI;NAIDU, G VENKATA; PRASAD,K KRISHNA;
RAO, N CHANDRASEKHAR; MOHAN, S VENKATA; JETTY,
ANNAPURNA; SARMA, PN; Anaer ob i c t r eat ment of
wast ewat er wit h high suspended solids from a bulk drug
indust ry using fixed film react or (AFFR)
Bioresource Technology (2004) 93(3) : 241-247
RAO, DS;PRASAD, DHL; Act ivit y coefficient s for t he binary
mixt ures of met hyl-et hylket one wit h some chlorohydro
carbons at 94.8 kPa
Physics and Chemist ry of Liquids (2004) 42(6) : 585-588
RAO, I NAGESHWAR;BORUAH, A;KUMAR, SK;KUNWAR,
AC;DEVI, AS;VYAS, K; RAVIKUMAR, K;IQBAL, J; Synt hesi s
and conf ormat i onal st udi es of novel cycl i c pept i des
co n st r ai n ed i n t o a 3(10) h el i cal st r u ct u r e b y a
het erochiral D-pro-L-pro dipept ide t emplat e
The Journal of Organic Chemist ry (2004) 69(6) : 2181-
2184
RAO, J VENKATESWARA; Effect s of monocrot ophos and
i t s anal ogs i n acet yl chol i nest erase act i vi t ys i nhi bi t i on
an d i t s p at t er n o f r eco ver y o n eu r yh al i n e f i sh ,
Oreochromi s mossambi cus
Ecot oxicology and Environment al Safet y (2004) 59(2)
: 217-222
RAO, J VENKATESWARA; KAVITHA, P; Toxicit y of azodrin
on t he morphol ogy and acet yl chol i nest erase aci t i vi t y
of t he eart hworm Ei seni a foet i da
Environment al Research (2004) 96(3) : 323-327
RAMU, R;RAVINDRANATH, N;REDDY, MR; DAS, B; St udies
on novel synt het i c met hod ol og i es. Par t 31. Si l i ca-
support ed sodi um hydrogen sul f at e-cat al yzed f aci l e
t r an sf or mat i on of p -h yd r oxyb en zyl al coh ol s t o p -
hydroxybenzyl et hers and t hi oet hers
RAMU, SRIDARALA;LINGAIAH, N;PRABHAVATHI DEVI,
LBN;PRASAD, RBN; SURYANARAYANA, I;SAI PRASAD, PS;
Est er i f i cat i on of p al mi t i c aci d w i t h met hanol over
t u n g st en o xi d e su p p o r t ed o n zi r co n i a so l i d aci d
cat alyst s: effect of met hod of preparat ion of t he cat alyst
on it s st ruct ural st abilit y and react ivit y
Applied Cat alysis A: General (2004) 276(1-2) : 163-
168
RANGANATHAN, S;MURALEEDHARAN, KM;VAISH,
NARENDRA K; JAYARAMAN, NARAYANASWAMY; Hal o-
and sel enol act oni sat i on: t he t wo maj or st rat egi es f or
cycl of unct i onal i sat i on
Tet rahedron (2004) 60(25) : 5273-5308
RANGANATHAN, S;RAO, Ch C;VUDAYAGIRI, YBRD;
RAJESH;JAGADEESH; Solubilizat ion of silica: Synt hesis,
ch ar act er i zat i o n an d st u d y o f p en t a- co o r d i n at ed
pyridine N-oxide silicon complexes
RANGANATHAN, S;CHERUKU, PRADEEP; MADHU SUDANAN,
KP;GEORGE, KS; On e-st ep t r an sf o r mat i o n o f 2-o xa-3-
azab i cycl o [ 2.2.1] h ep t -5-en e an d met h yl 2,3-
diazabicyclo[2.2.1]hept ane-2-carboxylat e t o ion upt ake syst ems
ARKIVOC (Gainesville, FL, Unit ed St at es) (2004) (8) :
28-36
RANI, AS; JETTY, A;RAMAKRISHNA, SV; Kinet ic st udies of
penicillin product ion during bat ch and repeat ed bat ch
i n f l ui di zed bed bi oreact or wi t h agar i mmobi l i zed P.
chrysogenum cel l s
Indian Journal of Biot echnology (2004) 3(3) : 394-
399
RANI, AS;SATYAKALA, M;MURTY, US; St evia rebaudiana,
bio-sweet ener of t he fut ure: A review
Asian Journal of Microbiology, Biot echnology and
Environment al Sciences (2004) 6(3) : 453-460
191
RAO, J VENKATESWARA;PALLELA, R;JAKKA, NM;USMAN,
PK; Suscept ibilit y of Cul ex qui nquefasci at us larvae t o t he
l ar vi ci de, Fent hi on (Bayt ex) at Hyderabad Ci t y, Indi a
Pest ology (2004) 28(12) : 19-22
RAO, J VENKATESWARA;SRIKANTH, K;CHAKRA REDDY,
N;SRIDHAR, V; Ef f ect of i mi d acl op r i d on l ocomot or
b eh avi o u r an d acet yl ch o l i n est er ase act i vi t y o f
subt erranean t ermit es, Odont ot ermes obesus
Pest ology (2004) 28(9) : 13-18
RAO, K RAJESWAR;RAO, S VENKATESWAR;CHARY, V;
Est i mat i o n o f r i sk i n d i ces o f ch emi cal s d u r i n g
t ransport at i on
Process Safet y Progress (2004) 23(2) : 149-154
RAO, KVS;SUBRAHMANYAM, M;BOULE, P; Immobi l i zed
Ti O
2
phot ocat al yst duri ng l ong-t erm use: decrease of
i t s act i vi t y
Applied Catalysis B: Environmental (2004) 49 (4) : 239-
249
RAO, M MOHAN;JAYALAKSHMI, M; REDDY, R
SUDARSHAN; Time-select ive hydrot hermal synt hesis of
SnS nanorods and nanopart icles by t hiourea hydrolysis
RAO, R NAGESWARA;ALVI, SN; HPLC st udies on evaluat ion of purit y
of pest icide reference st andard mat erials
Journal of Met rological Societ y of India (2004) 19 :
121-126
RAO, R NAGESWARA;NAGARAJU, V; Separat ion and det erminat ion
of synt het ic impurit ies of norfloxacin by reversed-phase high
performance liquid chromat o graphy
(2004) 34(5) : 1049-1056
RAO, R NAGESWARA; NAGARAJU, V; Sep ar at i on and
det ermi nat i on of synt het i c i mpuri t i es of di fl oxaci n by
r ever sed -p hase hi gh-p er f or mance l i qui d chr omat o
graphy
(2004) 36(4) : 729-735
RAO, R NAGESWARA;PARIMALA, P;KHALID, S;ALVI, SN;
Det ect i on of t he adul t erat i on of t radi t i onal al cohol i c
b ever ages b y t he sep ar at i on and d et er mi nat i on of
al p r azo l am, ch l o r al h yd r at e an d d i azep am u si n g
r ever sed -p hase hi gh-p er f or mance l i q ui d chr omat o
graphy
Analyt ical Sciences: The Internat ional Journal Of The
Japan Society For Analytical Chemistry , (2004) 20(2)
: 383-386
RAO, R NAGESWARA;NAGARAJU, D;ALVI, SN;BHIRUD, SB;
Devel op ment and val i d at i on of a l i q ui d chr omat o
g r ap h i c met h o d f o r d et er mi n at i o n o f r el at ed -
sub st ances of mosap r i d e ci t r at e i n b ul k d r ugs and
pharmaceut i cal s
Journal Of pharmaceut ical And Biomedical Analysis
(2004) 36(4) : 759-767
RAO, R NAGESWARA;SHANKARAIAH, B;SUNDER, MS;
Separat i on and det ermi nat i on of di ast ereomers of l -
cyhal ot hri n by normal phase-l i qui d chromat ography
using a CN column
RAO, R SREENIVAS;PRAKASHAM, RS;KRISHNA PRASAD,
K;RAJESHAM, S; SARMA, PN;RAO, L VENKATESWAR; Xylit ol
product i on by Candi da sp.: paramet er opt i mi zat i on
using Taguchi approach
Process Biochemist ry (2004) 39(8) : 951-956
RATNAMALA, A; DURGAKUMARI, V;SUBRAHMANYAM, M;
ARCHANA, N; CeZSM-5-a designers cat alyst for select ive
synt hesi s of oct ahydroacri di ne
(2004) (23) : 2710-2711
RATNAMALA, A;SUBRAHMANYAM, M;DURGA KUMARI,
V; Highly select ive and single st ep vapor phase synt hesis
of 2,6-b i s(4-met hyl p henyl )p yri di ne over Al -MCM-41
mol ecul ar si eves
RAVIKANTH, S;REDDY, G VENKAT;MAITRAIE, D;RAMA RAO,
VVVNS;RAO, P SHANTHAN;NARSAIAH, B Synt hesi s of
novel 5-Trifluoromet hyl-2,4,7-t risub st it ut ed pyrido[2,3-
d] pyrimidines
Synt het ic Communicat ions (2004) : 34(24) : 4463-
4469
Publications
192
RAVIKUMAR, K;SELVANAYAGAM, S;GOUD, TV;
KRISHNAIAH, P;VENKATESWARLU, Y A f u r o d ysi n i n
l act one deri vat i ve f rom t he mari ne sponge dysi dea
fragi l i s
Acta Crystallographica Section E (Str. Reports Online)
(2004) 60(Part 1) : 0139-0141
RAVIKUMAR, K;MAHESH, M;NARAYANA REDDY, VV; Imino
Di el s- Al d er ad d u ct s. I. Tw o f u r o [ 3,2- c] q u i n o l i n e
di ast ereoi somers
Act a Cryst allographica. Sect ion C, Cryst al St ruct ure
Communicat ions (2004) 60(12) : o887-o889
RAVINDER, K;REDDY, AV;KRISHNAIAH, P; VENKATA
RAMANA, G;REDDY, VLN; VENKATESWARLU, Y; Can
cat alyzed one-pot synt hesis of -amino phosphonat es
from carbonyl compounds
RAVINDRANATH, NASI;REDDY, M RAVINDER;RAMESH,
CHIMMANI; RAMU, RAVIRALA;PRABHAKAR, ANA
BATHULA; JAGADEESH, BHARATAM;DAS, B; New
Lat h yr an e an d Po d o car p an e Di t er p en o i d s f r o m
Jat ropha curcas
608-611
RAVINDRANATH, N;REDDY, M RAVINDER;RAMESH, C;DAS,
B; Deoxypressmerins from Jat ropha curcas: Are t hey also
pl ant met abol i t es?
Phyt ochemist ry (2004) 65(16) : 2387-2390
REDDY, BM;GANESH, IBRAM;KHAN; ATAULLAH ;
St ab i l i zat i on of nanosi zed t i t ani a-anat ase f or hi g h
t emperat ure cat al yt i c appl i cat i ons
223(1-2) : 295-304
REDDY, BM;LAKSHMANAN, PANDIAN;KHAN, ATAULLAH;
Invest igat ion of sur face st ruct ures of dispersed V
2
O
5
on
CeO
2
-Si O
2
, CeO
2
-Ti O
2
, and CeO
2
-ZrO
2
mi xed oxi des by
XRD, Raman, and XPS t echniques
Journal of Physi cal Chemi st ry B (2004) 108(43) :
16855-16863
REDDY, BM;SREEKANTH, PM;KHAN, A; Facile synt hesis of
1,1-di acet at es f rom al dehydes usi ng envi ronment al l y
benign solid acid cat alyst under solvent -free condit ions
REDDY, B RAMACHANDRA;KUMAR, J RAJESH;RAJA, K
PHANI;REDDY, A VARADA; Sol vent ext ract i on of Hf (IV)
from acidic chloride solut ions using cyanex 302
Minerals Engineering (2004) 17(7-8) : 939-942
REDDY, B RAMACHANDRA;KUMAR, J RAJESH;REDDY, A
VARADA; Li q u i d - l i q u i d ex t r act i o n o f t et r aval en t
zirconium from acidic chloride solut ions using cyanex
272
Analyt ical Sciences The Internat ional Journal Of The
Japan Societ y For Analyt ical Chemist ry (2004) 20(3)
: 501-505
VARADA; Solvent ext ract ion of zirconium(IV) from acid
chloride solut ions using LIX 84-IC
Hydromet allurgy (2004) 74(1-2) : 173-177
VARADA; Solvent ext ract ion of zirconium(IV) from acidic
ch l o r i d e so l u t i o n s u si n g t h e t h i o su b st i t u t ed
organophosphorus acids Cyanex 301 and 302
Journal of Chemical Technology and Biot echnology
(2004) 79(11) : 1301-1307
VARADA;NEELA PRIYA, D; So l ven t ext r act i o n o f
zirconium(IV) from acidic chloride solut ions using 2-et hyl
hexyl phosphoni c aci d mono-2-et hyl hexyl est er (PC-
88A)
REDDY, B RAMACHANDRA;RADHIKA, P;KUMAR, J
RAJESH;NEELA PRIYA, D; RAJGOPAL, K; Ex t r act i ve
sp ect r op hot omet r i c d et er mi nat i on of cob al t (II) i n
synt het i c and pharmaceut i cal sampl es usi ng Cyanex
923
193
VARADA; Sol vent ext r act i on of t et r aval ent haf ni um
f r om aci d i c ch l or i d e sol ut i on s usi n g 2-et h yl h exyl
phosphoni c aci d mono-2-et hyl hexyl est er (PC-88A)
Minerals Engineering (2004) 17(4) : 553-556
REDDY, B RAMACHANDRA;NEELA PRIYA, D; Sol ven t
ext ract ion of Ni(II) from sulfat e solut ions wit h LIX 841:
Flow-sheet for t he separat ion of Cu(II), Ni(II) and Zn(II)
REDDY, B RAMACHANDRA;NEELA PRIYA, D;KUMAR, J
RAJESH; So l ven t ext r act i o n o f cad mi u m (II) f r o m
sul phat e sol ut i ons usi ng TOPS 99,PC 88A, Cyanex 272
and t heir mixt ures
REDDY, K MADHUSUDAN;SATYANARAYANA, SUNKARA,
V MANORAMA;MISRA, RDK; A Comparat ive st udy of t he
gas sensi ng behavi or of nanost ruct ured ni ckel f erri t e
syn t h esi zed b y h yd r o t h er mal an d r ever semi cel l e
t echni ques
Mat erial Research Bullet in (2004) 39(10) : 1491-1498
REDDY, K MADHUSUDAN;GUIN, DEBANJAN;SUNKARA, V
MANORAMA; Select ive synt hesis of nanosized TiO2 by
h yd r o t h er mal r o u t e: Ch ar act er i zat i o n , st r u ct u r e
propert y relat ion, and phot ochemical applicat ion
Journal of Mat erials Research (2004) 19(9) : 2567-
2575
REDDY, M NARENDER;REHANA, TASNEEM; RAMA
KRISHNA, S;CHOWDHARY, KPR;DIWAN, PV; Bet a-
cycl o d ext r i n co mp l exes o f cel eco xi b : mo l ecu l ar -
modeling, charact erizat ion and dissolut ion st udies
AAPS PharmSci [Elect ronic Resource] (2004) 6(1) : E7
REDDY, M PRATAP;SRINIVAS, B;DURGA KUMARI,
V;SUBRAHMANYAM, M;SHARMA, PN; An i nt eg r at ed
ap p r o ach o f so l ar p h o t o cat al yt i c an d b i o l o g i cal
t r eat men t of N-con t ai n i n g or g an i c comp oun d s i n
wast ewat er
Toxicological and Environment al Chemist ry (2004)
86(1-4) : 125-138
REDDY, M SOMI;NARENDER, M;RAO, K RAMA;
Regener at i on of car b onyl comp ounds b y oxi dat i ve
cl eavage of oxi mes wi t h NBS i n t he p resence of b -
cyclodext rin in wat er
REDDY, P NAGI;SRIKANTH, R;BHANUPRAKASH, K;
SRINIVAS, R; Generat i on and charact eri zat i on of i oni c
and neut ral met hyl ene i sot hi ocyanat e by a combi nes
t andem mass spect romet ry and comput at i onal st udy
Rapid Communicat ions In Mass Spect romet ry (2004)
18(17) : 1939-1946
REDDY, P NAGI;SRIKANTH, R;SWAMY, NS; BHANU
PRAKASH, K;SRINIVAS, R; Gen er at i o n an d
charact eri zat i on of i oni c and neut ral sel enocumul ene
HC3Se+ / . b y t an d em mass sp ect r o met r y an d
comput at i onal st udy
232(3) : 231-237
REDDY, SKVN;PRASAD, DHL;KRISHNAIAH, ABBURI; Vapor-
Li q u i d Eq u i l i b r i a f o r t h e Bi n ar y Syst ems o f
d i met h o xymet h an e w i t h so me f u el o xyg en at es -
Journal of Chemical and Engineering Dat a 49(6) :
1546-1549
REDDY, S VENKAT;PULLELA, V;SRINIVAS, B;PRAVEEN,
K;HARA KISHORE, B;CHINA RAJU; MURTHY, U
SURYANARAYANA; RAO,J MADHUSUDANA;
Ant i bact eri al const i t uent s f rom t he berri es of Pi per
ni grum
Phyt omedicine (2004) 11(7-8) : 697-700
REDDY, T JAGADESHWAR;PRABHAKAR, S;VIJAYA
SARADHI, UVR;RAO, VJ; VAIRAMANI, M; Mass sp ect ral
st udy on O,O-di al kyl N,N-di al kyl p hosp horami dat es
under elect ron impact condit ions
Jour nal Of The Amer i can Soci et y For M ass
Spect romet ry (2004) 15(4) : 547-557
REDDY, T JAGADESHWAR;VIJAYA SARADHI, UVR;
PRABHAKAR, S;VAIRAMANI, M; Trace level det ect ion and
i d ent i f i cat i on of chemi cal s r el at ed t o t he chemi cal
weapons convent ion from complex organic samples -
Journal of Chromat ography A (2004) 1038(1-2) : 225-
230
Publications
194
REDDY, T THIMMA; TAMMISHETTI, SHEKHARAM Free
radical degradat ion of guar gum
Polymer Degradation and Stability (2004) 86(3) : 455-
459
REDDY, V YARAPATHY;SAMBASIVUDU, K;TAMMISHETTI,
SHEKHARAM; Synt hesis of dihydropyrimidinones using
r eusab l e p ol y(4-vi n yl p yr i d i n e co d i vi n yl b en zen e)
Cu(II)complex
Cat alysis Communicat ions (2004) 5(9) 511-513
REDDY, V YARAPATHY ; Novel angular furanocoumarins:
Synt hesi s of 8-aroyl -9-st yryl f urobenzopyran-2-ones
Het erocyclic Communicat ions (2004) 10(1) : 59-62
SABITHA, G;REDDY, EV;SWAPNA, R;REDDY, NM;YADAV, JS;
Bi smut h(III) chl ori de cat al yzed ef f i ci ent and sel ect i ve
cleavage of t rit yl et hers
Synlet t (2004) (7) : 1276-1278
SABITHA, G;REDDY, GSKK;REDDY, KB;YADAV, JS; Iodot ri
met hyl si l ane-medi at ed cross-al dol condensat i on: A
f aci l e syn t h esi s o f al p h a, al p h a - b i s (su b st i t u t ed
benzyl i dene) cycl oal kanones
SABITHA, G;VENKATA REDDY, E;FATIMA, N;YADAV,
JS;RAMA KRISHNA, KVS; KUNWAR, AC;
Di ast ereosel ect i ve synt hesi s of chi ral ci s-annul at ed
p ol ycycl i c het er ocycl es f r om D-gl ucose b y domi no
Knoevenagel -het ero-Di el s Al der react i ons
SABITHA, G;KIRAN KUMAR, GS;REDDY, K BHASKAR;
REDDY, N MALLIKARJUNA;YADAV, JS; A new, efficient and
envi ronment al l y beni ng prot ocol f or t he synt hesi s of
1,5-benzodiazepines using cerium (III) chloride/ sodium
iodide support ed on silica gel
923
SALEHA BANU, B;ISHAQ, MOHD;DANADEVI, K;PADMA
VATHI, P;AHUJA, YR; DNA damage in leukocyt es of mice
t reat ed wit h copper sulfat e
Food And Chemical Toxicology: (2004) 42(12) : 1931-
1936
SASTRY, GSR;RAVI PRASAD, P; Det erminat ion of alcoholin
pet rol -al cohol mi xt ures
Indian Journal of Chemical Technology (2004) 11(5) :
323-325
SATYA KUMAR, DVR;KRISHNA, D;MURTY, US;SAI, KSK -
Imp act o f d i f f er en t h o u si n g st r u ct u r es o n f i l ar i al
t ransmission in rural areas of sout hern India
Sout heast Asian Journal of Tropical Medicine and
Public Healt h (2004) 35(3) : 587-590
SHAILAJA, M;MANJULA, A;RAO, BV;PARVATHI, N; Simple
p r ot ocol f or t he synt hesi s of 3,4-di hydr op yr i mi di n-
2(1H)-ones usi ng SnCl 22H2O-Li Cl as an i nexpensi ve
cat al yst syst em
Synt het ic Communicat ions (2004) 34 (9) : 1559-1564
SEKAR, R;AZHAGUVEL, S; Indi rect phot omet ri c assay
det erminat ion of gabapent in in bulk drug and capsules
by capi l l ary el ect rophoresi s
(2004) 36(3) : 663-667
D;RAVIKUMAR, K;SURESH BABU, AR;RAGHUNATH, R; 4-
(3- ch l o r o p h en yl )- 1- METHYL- 1H- i n d o l e- 3- sp i r o - 2 -
pyrrol i di ne-3-spi ro-2-i ndan-2,1,3-t ri one
Act a Cryst allographica Sect ion E (St ruct ure Report s
Online) (2004) 60(Part 1) : 051-053
D;RAVIKUMAR, K; SURESH BABU, AR;RAGHUNATH, R; 2-
(p-Chlorobenzoyl)-2,2,3,3,4,5,6,6-oct ahydro-1H-indan-
2-spi ro-3-(1H-pyrol i zi ne)1-spi ro-3-i ndol i ne-1,2 ,3-
t ri one
Online) (2004) 60(Part 1) : 0126-0128
5,7-dibromo-4 -(4-bromobenzoyl)-1 -met hyl-1H-indole-
3-spiro-2 -pyrrolidine-3 -spiro-3 -1H-indole-2,2 (3H,3
H)-dione met hanol solvat e
Online)(2004) 60(Part 5):O870-O872
195
5,7-d i b r omo-1 -met hyl -2 -(4-met hoxyb enzoyl )-1H-
indole-3-spiro-2 -pyrrolidine-3 -spiro-3 -1H-indole-2,2
(3H,3 H)-dione met hanol solvat e
Acta Crystallographica , Section E (Stru Reports Online)
(2004) 60(Part 4):O550-O552
SHARMA, GVM;KUMAR, K RAMAN; St ud i es d i r ect ed
t owards t he t ot al synt hesis of feigrisolide B
SHARMA, GVM; PENDEM, NAGENDAR; REDDY, K RAVINDER; RADHA
KRISHNA, PALAKODETY; NARSIMULU, K;KUNWAR, AC; The
st ereosel ect i ve synt hesi s of C-l i nked 42 -deoxy aza-
disaccharides from C-linked carbo--amino acids
SHARMA, GVM;PRASAD, TR;RAKESH;SRINIVAS, B; p -
met h o xy d i p h en yl met h an o l (MDPM), p - p h en yl
d i p h en yl met h an o l (PDPM) , an d p - p h en yl p h en yl
d i p h en ymet h an o l (PPDM Pr o t ect i n g g r o u p s f o r
alcohols- Prot ect ion and deprot ect ion
SHARMA, GVM;REDDY, Ch GOVARDHAN; A st er eo
sel ect i ve synt hesi s of verbal act one-det ermi nat i on of
absol ut e st ereochemi st ry
SHARMA, GVM;REDDY, J JANARDHAN;SREE LAKSHMI,
P;RADHAKRISHNA, P; Rap i d an d f aci l e Lew i s aci d
cat alyzed Boc prot ect ion of amines
SHARMA, GVM;REDDY;K LAXMA;SREE LAKSHMI, P;
RADHA KRISHNA, P; An ef f i ci en t p r o t o co l f o r t h e
p r ep ar at i on of MOM et her s and t hei r dep r ot ect i on
using zirconium(IV) chloride
SHARMA, GVM;REDDY, K RAVINDER;RADHA KRISHNA,
P;RAVI SHANKAR, A;JAYAPRAKASH, P;JAGANNADH,
B;KUNWAR, AC; Lef t handed helical t wist s in Mixed b-
Pept i des deri ved f rom al t ernat i ng C-Li nked Carb b
3
-
Amino acids and b-hGly unit s
Angewandt e Chemie Int ernat ional Edit ion (2004) 43 :
3961-3497
SHARMA, GVM; REDDY, J JANARDHAN;SREE LAKSHMI,
P;RADHA KRISHNA, P; A versat ile and pract ical synt hesis
of bi s(i ndol yl )met hanes/ bi s(i ndol yl )gl ycoconj ugat es
cat alyzed by t richloro-1,3,5-t riazine
SHARMA, GVM;BEGUM, ASRA;RAKESH;RADHA KRISHNA,
P; Zirconium(IV) chloride mediat ed cyclodehydrat ion of
1,2-di acyl hydrazi nes: a conveni ent synt hesi s of 2,5-
diaryl-1,3,4-oxadizole derivat ives
SHARMA, GVM;PUNNA, SREENIVAS;RATNAMALA,
A;DURGA KUMARI, V;SUBRAHMANYAM, M; Zeol i t e-
medi at ed conversi on of al cohol s t o p-met hoxybenzyl
et hers
(2004) 36(6) : 581-586
SHARMA, GVM;RADHA KRISHNA, P; Carbohydrat es: from
chi rons t o newgl ycosubst ance
Current Organic Chemist ry (2004) 8(13) : 1187-1209
SHARMA, GVM;SUBHASH CHANDER, A;RADHA KRISHNA,
P;KRISHNUDU, K; RAMANA, RAO, MHV;KUNWAR, AC;
Synt hesis of pseudo saccharide precursors t hrough Off
t emplat e sit e Michael Wit t ig react ion on sugar derived
enal
Arkivoc (2004) : 12
SHIREEN, KF;MAHBOOB, M;KHAN, AT; Ef f ect s of shor t
t erm mercury exposure on ant i oxi dant s enzymes and
lipid peroxidat ion in different organs of rat
Toxicology Int ernat ional (2004) 11(1) : 1-7
Publications
196
SINGH, HARJINDER;ARORA, KARUNESH;TAPADAR,
S;CHAKRABORTY, TK; Preferent i al pol ymeri zat i on of 5-
(Ami nomet hyl )2-Furancarboxyl i c aci d (AMFC) i nt o a
cyclic t ripept ide
Journal of Theoret ical and Comput at ional Chemist ry
(2004) 3(4) : 555-556
SMITHA, B;SRIDHAR, S;KHAN, AA; Po l yel ect r o l yt e
complexes of chit osan and poly(acrylic acid) as prot on
exchange membranes for fuel cells
Macromolecules (2004) 37(6) : 2233-2239
SMITHA, B;SRIDHAR, S;KHAN, AA; Syn t h esi s an d
charact erizat ion of Sulfonat ed PEEK membranes for fuel
cell applicat ions
SMITHA, B;SUHANYA, D;SRIDHAR, S;RAMAKRISHNA, M;
Sep ar at i o n o f o r g an i c- o r g an i c mi xt u r es b y
pervaporat ion -a review
Journal of Membrane Science (2004) 241(1) : 1-21
SREEDHAR, B;SWAPNA, V;SRIDHAR, CH; Bi smut h(III)
t riflat e: Novel and efficient cat alyst for Claisen and Fries
rearrangement s of allyl et hers and phenyl est ers
SRIDHAR, C; SUBBARAJU, GV; VENKATESWARLU, Y;
VENUGOPAL, RT; New acylat ed iridoid glucosides from
Vit ex alt issima
Journal of Natural Products (2004) 67(12) : 2012-2016
SRIDHAR, S;RAO, A GANGAGNI; Treat ing Effluent s in Bulk
Drug i ndust ry usi ng Reverse Osmosi s
Pharma Bio World (2004) Feb-Apr : 91-97
SRIDHAR, S;SMITHA, B; Perf ormance and Prospect s of
Nan o f i l t r at i o n f o r Sep ar at i o n s i n Ph ar maceu t i cal
manuf act ure
Journal of Mass Spect romet ry (2004) May-June : 77-83
SRIDHAR, S;SMITHA, B;MADHAVI LATHA, US; RAMA
KRISHNA; Pervaporat ion of 1,4-Dioxane/ Wat er mixt ures
using poly(vinyl alcohol) membranes crosslinked wit h
t ol uyl ene-2,4-di i socyanat e
SRIKANTH, R;BHANUPRAKASH, K;SRINIVAS, R;WONG,
CY;TERLOUW, JK; Prot onat ed si l anoi c aci d Hi s (OH) (2)
(+ ) an d i t s n eu t r al co u n t er p ar t : a t an d em mass
spect romet ri c and CBS-QB3 comput at i onal st udy
Journal of Mass Spect romet ry (2004) 39(3) : 303-311
SRIKANTH, R;REDDY, P NAGI;SRINIVAS, R;SHARMA,
GVM;REDDY, K RAVINDER; Mass spect ral st udy of alkali-
cat ionized Boc-Carbo-b3-pept ideselect rospray t andem
mass spect romet ry
18(24) : 3041-3050
SRIKANTH, R;SRINIVAS, R;SHARMA, GVM;RAVINDER
REDDY, K;RADHA KRISHNA, P; Mass spect ral st ud y of
Boc-carbo-3-pept i des: di f f erent i at i on of t wo pai rs of
posi t i onal and di ast ereomeri c i somers
Journal of Mass Spect romet ry (2004) 39(9) : 1068-
1074
SRILAXMI, Ch ;LINGAIAH, N;HUSSAIN, AHMAD;SAI
PRASAD, PS; NARAYANA, KV;MARTIN, A;LUCKE, B; In sit u
synt hesis and ammoxidat ion act ivit y of ammonium salt
of molybdophosphoric acid on VOPO4 cat alyst s
SRINIVAS, K;NAIR, CKS;RAMESH, S;PARDHASARADHI, M;
An improved synt hesis of 5-(2-flurophenyl)-1H-t et razole
Organic Preparat ions & Procedures I nt ernat ional
(2004) 36(1) : 69-71
SRINIVAS, K;NAIR, CKS;RAMESH, S;PARDHASARADHI, M;
A rapid and efficient synt hesis of 2-but yl-5-chloro-3H-
imidazole-4-carboxaldehyde
SRINIVAS, KVNS;DAS, B; Io d i n e cat al yzed o n e- p ot
syn t h esi s of 3,4-d i h yd r op yr i mi d i n -2(1H)-on es an d
t hi ones: A si mpl e and effi ci ent procedure for Bi gi nel l i
react i on
Synt hesis_St ut t gart (2004) (13) : 2091-2093
SRINIVAS, KVNS;DAS, B; An ef f i ci ent one-pot synt hesi s
of pyrano and furoquinolines employing t wo reusable
sol i d aci ds as het erogeneous cat al yst s
Synlet t (2004) (10) : 1715-1718
197
SRINIVAS, PV;REDDY, S VENKAT;SREELATHA, T; HARA
KISHORE, K;PRAVEEN, B;MURTHY, US;RAO, JM; A new
met h o d o f syn t h esi s an d an t i b act er i al aci t i vi t y
evaluat ion of piper amides
Nat ural Product Research (2004) 18(1) : 95-98
SUMAN, RAJ DS;CHARY, NS;BINDU, VH;REDDY, MRP;
ANJANEYULU, Y; Aerobic oxidat ion of common effluent
t reat ment pl ant wast ewat ers and sl udge charact er-i
zat i on st udi es
International Journal of Environmental Studies (2004)
64(1) : 99-111
SUMAN, N JOHN;REDDY, YARAPATHY, V;RAJU, KVSN; TAMMISHETTI,
SHEKHARAM; Ef f ect of epxoy resi n on cure behavi our and
t hermal propert ies of cyanat e est er resin
Int ernat ional Journal of Plast ics Technology (2004)
8(1) : 180
SUNIL SINGH, RAJKUMAR;CHAUDHURI, ARABINDA;
Single addit ional met hylene group in t he head-group
r eg i o n i mp ar t s h i g h g en e t r an sf er ef f i cacy t o a
t ransfect ion- incompet ent cat ionic lipid
FEBS Let t ers (2004) 556(1-3) : 86-90
SUNIL SINGH, RAJKUMAR;GONALVES, CHRISTINE;
SANDRIN PIERRE; PICHON, CHANTAL;MIDOUX, PATRICK;
CHAUDHURI, A; On t he gene delivery efficacies of pH-
Sensit ive Cat ionic Lipids via Endosomal Prot onat ion: A
Chemi cal Bi ol ogy Invest i gat i on
Chemist ry and Biology (2004) 11(5) : 713-723
SURENDRA, K;KRISHNAVENI, NS;RAO, K RAMA ; A new
and efficient met hod for t he synt hesis of t hiiranes from
oxirane-cyclodext rin complexes and t hiourea in wat er
SURENDRA, K;KRISHNAVENI, NS;RAO, K RAMA; A s5imple
biomimet ic prot ocol for t he oxidat ion of alcohols wit h
sodium hypochlorit e in t he presence of -cyclodext rin
in wat er
Canadian Journal of Chemist ry (2004) 82(7) : 1230-
1233
SURESH BABU, K;TIWARI, ASHOK K;SRINIVAS, PULLELA
V;ALI, AMTUL Z; RAJU, B CHINA;RAO, JM; Yeast and
mammal i an al pha-gl ucosi dase i nhi bi t ory const i t uent s
from Himalayan rhubarb Rheum emodi Wall.ex Meisson
14(14) : 3841-3845
SURESH BABU, K;RAJU, BC; RAO, AS; KUMAR, SP; RAO,
JM; Bi smut h t r i f l at e cat al yzed one-p ot synt hesi s of
t et rahydrochromanoqui nol i nes
SURESH, KI;OTHERGRAVEN, JENS;RAJU, KVSN;BARTSCH,
ECKHARD; Mechanist ic st udies on part icle nucleat ion in
t he bat ch emulsion polymerizat ion of n-but yl acrylat e
cont ai ni ng mul t i f unct i onal monomers
Colloid & Polymer Science (2004) 283(1) : 49-57
SWAMY, NR;GOUD, TV;REDDY, SM;KRISHNAIAH, P;
VENKATESWARLU, Y; Zi rconi um (IV) chl ori de cat al yzed
r i n g o p en i n g o f ep o xi d es w i t h a r o mat i c ami n es
SWAMY, NR;SRINIVASULU, M;REDDY, T SRIKANTH;GOUD,
TV;VENKATESWARLU, Y; Zirconium (IV) chloride cat alyzed
synt hesi s of 2,3-Unsat ur at ed C,N,O,S, and Het er oa-
romat i c gl ycosyl at i on i n t he Ferri er rearrangement
Journal of Carbohydrat e Chemist ry (2004) 23(6&7) :
435-441
M, ML;IWASAWA, Y ; Chiral self-dimerizat ion of vanadium
compl exes of a Si O
2
surf ace: t he f i rst het erogeneous
cat alyst s for asymmet ric coupling of napht hol
TIWARI, AK; Ant i oxi dant s: New-generat i on t herapeut i c
base for t reat ment of polygenic disorders [Review]
Current Science (2004) 86(8) : 1092-1102
USHA RANI, P ; Act ivit y of plant derived ext ract s and oils
agai nst f our gener a of b act er i a vi z St ap hyl ococcus
aureus, Bacillus cereus, Escherichia coli I and Escherichia
coli II
Journal of Applied Zoological Research (2004) 15(2)
Publications
198
USHA RANI, P; At t ract ion of leaf surface chemicals from
yel l o w st em b o r er i n f est ed r i ce p l an t s t o i t s eg g
parasit oid, Trichogramma j aponicum (Ashmead)
Egg Parasit oid News (2004) (15) : 19-20
USHA RANI, P; Ant en n al sen si l l a of Tr i ch o g r amma
j aponicum an egg parasit oid of rice yellow st em borer
and it s relat ion t o kairomone percept ion
Egg Parasit oid News (2004) (15) : 20
USHA RANI, P;LAKSHMINARAYANA, M;INDU KUMARI, S;
Short range kai romones and ovi posi t i on st i mul ant s
from t he host Achea j anat a (L) infest ed cast or plant s t o
Trichogramma chilonis and Trichogramma achaea
Egg Parasit oid News (2004) (15) : 19
VARALA, RAVI;RAMU, E;ALAM, M MUJAHID;ADAPA,
SRINIVAS R; Scope and ut ilit y of CsOHH
2
O in aminat ion
react i ons vi a di rect coupl i ng of aryl hal i des and sec-
alicyclic amines
Synlet t (2004) (10) : 1747-1750
VARALA, R;RAMU, E;ALAM, M MUJAHID;ADAPA,
SRINIVAS, R; CsOHH2O-p r omot ed syn t hesi s of ar yl
sul f i des vi a di rect coupl i ng of aryl hal i des and t hi ol s
Chemist ry Let t ers (2004) 33 (12) : 1614-1615
VEDARAMAN, N;BRUNNER, G;KANNAN, C
SRINIVASA;MURALIDHARAN, C;RAO, PG;RAGHAVAN, KV;
Ext r act i o n o f ch o l est er o l f r o m cat t l e b r ai n u si n g
supercrit ical carbon dioxide
The Journal of Supercrit ical Fluids (2004) 32(1-3) :
231-242
VENKAT NARSAIAH, A;BASAK, AK; NAGAIAH, K;
Cadmi um chl ori de: An ef f i ci ent cat al yst f or one-pot
synt hesi s of 3,4-di hydropyri mi di n-2(1H)-ones
VENKAT NARSAIAH, A;BASAK, AK;VISALI, B;NAGAIAH, K;
An eco f r i en d l y syn t h esi s of el ect r op h i l i c al ken es
cat al yzed by di met hyl ami nopyri di ne under sol vent -
free condi t i ons
Synt het ic Communicat ions (2004) 34(16) : 2893-
2901392.
VENKAT NARSAIAH, A;NAGAIAH, K; An ef f i ci ent and
improved met hod for t he preparat ion of nit rides from
primary amides and aldoximes
1271-1274
VENKAT NARSAIAH, A;NAGAIAH, K; An Eco-f r i end l y
synt hesis of diaryl et hers wit hout cat alyst under micro
wave i rradi at i on
Indian Journal of Chemist ry, Sect ion-B (2004) (11) :
2478-2481
VENKATESWARLU, CH; Advances in Monit oring and St at e
Est i mat i on of Bi oreact ors
Journal of Scient ific and Indust rial Research (2004)
63 : 491-498
VENKATESWARLU, CH;ANURADHA, R; Dynami c Fuzzy
Adapt ive Cont roller for pH
Chemical Engineering Communicat ions (2004) 191 :
1564-1588
VENKATESWARLU, CH;GANGIAH, K; Co n st r ai n ed
general i zed predi ct i ve cont rol of unst abl e nonl i near
processes
Chemical Engineering Research and Design (2004)
75(3) : 371-376
VENUGOPAL, A;SCURRELL, MS; Lo w t emp er at u r e
reduct ive pret reat ment of Au/ Fe
2
O
3
cat al yst s, TPR/ TPO
st udies and behaviour in t he wat er-gas shift react ion
VENUGOPAL, D;SRINIVAS, B;SHARMA, M VENKATA
PHANIKRISHNA;PANDA, LIPSA; ANIL KUMAR, PULLUR;
SUBRAHMANYAM, M;DURGA KUMARI, V; Hydrogenat i on of
acet ophenone over bifunct ional mult imet al oxide cat alyst s
React ion Kinet ics and Cat alysis Let t ers (2004) 83(1) :
63-70
VIJAY, DOLLY;PRIYAKUMAR, UD;SASTRY, G NARAHARI;
Bas9i s set and met hod dep endence of t he r el at i ve
energies of C2S2H2 isomers
Chemical Physics Let t ers (2004) 383(1-25) : 192-197
199
VIJAY NAIR;SMITHA M, NAIR;MATHAI, SINDHUJURGEN
LIEBSCHER, BURKHARD ZIEMER AND NARSIMULU, K; The
Rh(II) cat alyzed react ion of diet hyl diazomalonat e wit h
t hi et anes: a f aci l e synt hesi s of t et rahydrot hi ophene
derivat ives via sulfonium ylides
VIJEETA, T;REDDY, JRC;RAO, BVSK;KARUNA, MSL;PRASAD,
RBN; Ph o sp h o l i p ase- med i at ed p r ep ar at i o n o f 1-
ri ci nol eoyl -2-acyl -sn-gl ycero-3-phosphochol i ne f rom
soya and egg phosphat i dyl chol i ne
Biot echnology Let t ers (2004) 26(13) : 1077-1088
VINOD KUMAR, VALLURIPALLI;CHAUDHURI, ARABINDA;
On t he disulfide-linker st rat egy for designing efficacious
cat ionic t ransfect ion lipids: an unexpect ed t ransfect ion
profile
FEBS Let t ers (2004) 571(1-3) : 205-211
YADAV, JS;RAJAIAH, G; A convergent synt hesi s of t he
C31-C46 fragment of phorboxazoles
Synlet t (2004) (9) : 1537-1540
YADAV, JS;RAJAIAH, G; A convergent synt hesi s of t he
C31-C46 fragment of phorboxazoles
Synlet t (2004) (10) : 1743-1746
YADAV, JS;REDDY, BVS; BASAK, AK;NARSAIAH, A VENKAT;
Recyclable 2
nd
generat ion ionic liquids as green solvent s
f or t he oxi dat i on of al cohol s wi t h hyperval ent i odi ne
reagent s
Tet rahedron (2004) 60(9) : 2131-2135
YADAV, JS;REDDY, BVS;BASAK, AK;NARSAIAH, A VENKAT;
Baeyer -Vi l l i g er oxi d at i on s i n i on i c l i q ui d s. A f aci l e
conversion of ket ones t o est ers and lact ones
YADAV, JS;REDDY, BVS;BASAK, AK;VISALI, B;NARSAIAH,
AV;NAGAIAH, K; Phosp hane-cat al yzed knoevenagel
condensat ion: A facile synt hesis of alpha-cyanoacrylat es
and al pha-cyanoacryl oni t ri l es
European Journal of Organic Chemist ry (2004) (3) :
546-551
YADAV, JS;REDDY, BVS;BAISHYA, G;REDDY, PV; HARSHA
VARDHAN, SJ; Bi smut h t ri f l at e as novel and ef f i ci ent
cat al yst for t he synt hesi s of bet a-ami nosul fi des
YADAV, JS;REDDY, BVS;ESHWARAIAH, B;GUPTA, MANOJ
KUMAR; Bi (Ot f )3/ [ b mi m] BF
4
as novel and r eusab l e
cat alyt ic syst em for t he synt hesis of furan, pyrrole and
t hi ophene deri vat i ves
YADAV, JS;REDDY, BVS;ESHWARAIAH, B;SRINIVAS, M;
Mont mori l l oni t e KSF cl ay cat al yzed one-pot synt hesi s
of ami noni t ri l es
Tet rahedron (2004) 60(8) : 1767-1771
YADAV, JS;REDDY, BVS;GUPTA, MK;BISWAS, SK; Rapid and
ef f i ci ent p rot ocol f or t he synt hesi s of 4-chl orot et ra
hydro pyrans using niobium(V) chloride
YADAV, JS;REDDY, BVS;GUPTA, MK;PRABHAKAR, A;
JAGADEESH, B; Fi r st examp l e of r i ng exp ansi on of
act i vat ed q u i n o l i n es an d i so q u i n o l i n es: No vel
benzoazepi nes
Chemical Communicat ions (2004) 10(18) : 2124-2125
YADAV, JS;REDDY, BVS;NAVEENKUMAR, V;RAO,
RS;NAGAIAH, K; [Bmim] PF6/ CuBr: a novel and recyclable
cat alyt ic syst em for t he synt hesis of propargyl amines
YADAV, JS;NAIDU, JJ;SADASHIV, K ; NBCL5-cat al yzed
r ap i d an d ef f i ci en t syn t h esi s o f 3,4d i h yd r o
pyri mi di nones under ambi ent condi t i ons
YADAV, JS;REDDY, BVS;PADMAVANI, B; Incl 3-cat al yzed
t an d em Mi ch ael / Fr i ed el -cr af t s cycl i zat i on : a n ovel
p r o t o co l f o r ch i r al 2,4- d i su b st i t u t ed t et r a h yd r o
qui nol i nes
Publications
200
YADAV, JS;REDDY, BVS;PARIMALA, G;RAJU, A KRISHNAM;
Bi smut h t ri f l at e cat al yzed condensat i on of hydroxy-
unsat urat ed al dehydes wi t h aryl ami nes
YADAV, JS;REDDY, BVS;REDDY, Ch SRINIVAS; Select fluor
TM
: a novel and efficient reagent for t he synt hesis of
hydroxy t hi ocyanat es
YADAV, JS;REDDY, BVS;REDDY, KS;CHANDRAIAH,
L;SUNITHA, V; Bi(Ot f )
3
as novel and efficient cat alyst for
t h e st er eo sel ect i ve syn t h esi s o f C- p seu d o g l ycal s
YADAY, JS;REDDY, BVS;REDDY, RSR;BASAK, AK;
NARSAIAH, AV; Ef f i ci en t h al o g en at i on of ar omat i c
syst ems using N-halosuccinimides in ionic liquids
Advanced Synt hesis & Cat alysis (2004) 346(1) : 77-82
YADAV, JS; REDDY, BVS; SADASHIV, K; PADMAVANI, B; [4+2]
Cycl oaddi t i on of ort ho-qui none met hi des promot ed
by ionic liquids: An efficient and mild prot ocol for t he
synt hesi s of t et rahydropyranobenzopyrans
610
YADAV, JS;REDDY, BVS;SADASHIV, K;RAGHAVENDRA,
S;HARIKISHAN, K; Mont mori l l oni t e KSF/ Si O
2
as novel
an d r ecycl ab l e so l i d aci d s f o r t h e syn t h esi s o f -
ami nohal i des and-azi doami nes
YADAV, JS;REDDY, BVS;REDDY, MS;NIRANJAN, N; Eco-
f r i en d l y h et er o g en eo u s so l i d aci d s as n o vel an d
r ecycl ab l e cat al yst s i n i o n i c med i u m f o r
t et rahydropyranol s
210(1-2) : 99-103
YADAV, JS;REDDY, BVS;SATHEESH, G;NAGA LAKSHMI,
P;KIRAN KUMAR, S; KUNWAR, AC; Rapi d and ef f i ci ent
synt hesi s of opt i cal l y act i ve pyrazol es under sol vent -
free condi t i ons
YADAV, JS;REDDY, BVS;SREEDHAR, P;RAO, RS;NAGAIAH,
K; Si l ver p hosp hot ungst at e: A novel and recycl ab l e
het eropoly acid for Friedlander quinoline synt hesis
Synt hesis (2004) (14) : 2381-2385
YADAV, JS;REDDY, BVS;SRIDHAR, P;REDDY, JSS;NAGAIAH,
K;LINGAIAH, N;SAIPRASAD, PS; Green prot ocol for t he
biginelli t hree-component react ion: Ag3PW12040 as a
novel , wat er-t ol erant het eropol yaci d for t he synt hesi s
of 3,4-di hydropyri mi di nones
European Journal of Organic Chemist ry (2004) (3) :
552-557
YADAV, JS;REDDY, BVS;SRINIVAS, M;PADMAVANI, B;
CeCl
3
.H
2
0/ NaI-Promot ed st ereoselect ive synt hesis of 2,4-
di subst i t ut ed chi ral t et rahydroqui nol i nes
Tet rahedron (2004) 60(14) : 3261-3266
YADAV, JS;REDDY, BVS;SHUBASHREE, S;SADASHIV, K;
Iodine/ MeOH: a novel and efficient reagent syst em for
t hi ocyanat i on of aromat i cs and het eroaromat i cs
YADAV, JS;REDDY, BVS;SHUBASHREE, S;SADASHIV,
K;NAIDU, JJ; Ioni c l i qui ds-promot ed mul t i -component
r eact i on: Gr een Ap p r oach f or hi ghl y sub st i t ut ed 2-
ami nof uran deri vat i ves
Synt hesis (2004) (14) : 2376-2378
YADAV, JS;REDDY, BVS;SWAMY, T; In Br 3- cat al yzed
conj ugat e addit ion of Indoles t o p-quinones: An efficient
synt hesi s of 3-i ndol yl qui nones
201
YADAV, JS;REDDY, BVS;SWAMY, T;RAMIREDDY, N; Ioni c
l i qui ds-promot ed addi t i on of aryl sul f i ni c aci ds t o P-
quinones- A green synt hesis of diaryl sulfones
YADAV, JS;REDDY, BVS;SATHEESH, G; Mont mori l l oni t e
cl ay cat al yzed al kyl at i on of pyrrol es and i ndol es wi t h
cyclic hemi-acet als
YADAV, JS;REDDY, BVS;NARSIMHASWAMY, D;NAGA
LAKSHMI, P;NARSIMULU, K;SRINIVSULU, G;KUNWAR, AC;
Domi no Knoevenagel het ero-Di el sAl der react i ons: a
st er eo sel ect i ve syn t h esi s o f su g ar f u sed f u r o [ 3,2-
b]pyrano[4,3-d]pyran deri vat i ves
YADAV, JS;REDDY, BVS;REDDY, Ch SURESH; InCl
3
/ IBX: a
novel reagent syst em for t he conversion of glycals int o
,-unsat urat ed -l act ones
YADAV, JS;REDDY, BVS;PREMALATHA, K;Bi (OTf )(3)-
cat al yzed f r i ed l an d er h et er o - an n u l at i o n : A r ap i d
synt hesis of 2,3,4-t risubst it ut ed quinolines
Synlet t (2004) (6) : 963-966
YADAV, JS;REDDY, BVS;PRAVEENKUMAR, S;NAGAIAH,
K;LINGAIAH, N; SAIPRASAD, PS; Ag3PW12O40: A novel
and recyclable het eropoly acid for t he synt hesis of 1,5-
benzodiazepines under solvent -free condit ions
YADAV, JS;REDDY, BVS;REDDY, CS;RAJASEKHAR, K; Green
prot ocol f or t he synt hesi s of vi ci nal -hal ohydri ns f rom
oxi r an es usi n g t h e [ Bmi m] PF6/ Li X r eag en t syst em
YADAV, JS;REDDY, BVS;SADASHIV, K;HARIKISHAN,
K;NARSAIAH, AV; Acyl at i ve cl eavage of azi ri di nes wi t h
acid anhydrides cat alyzed by Scandium t riflat e
220(2) : 153-157
YADAV, JS;REDDY, BVS;SRINIVAS, M;PRABHAKAR,
A;JAGADEESH, B; Mont mori l l oni t e KSF cl ay-promot ed
syn t h esi s o f en an t i o mer i cal l y p u r e 5- su b st i t u t ed
pyrazol es from 2,3-di hydro-4H-pyran-4-ones
YADAV, JS;REDDY, BVS;SWAMY, T;RAO, K RAGHAVENDER;
Bi (Ot f )3-cat al yzed acyl at i on of p -qui nones: a f aci l e
synt hesi s of acyl at ed hydroqui nones
YADAV, JS;REDDY, BVS;VENUGOPAL, Ch;PADMAVANI, B;
In Cl 3/ Si O
2
- cat al yzed - ami n at i o n o f 1,3- d i car b o n yl
compounds under mi crowave i rradi at i on
YADAV, JS;REDDY, K BHASKAR;SABITHA, G; An ef f i ci ent
synt hesis of (+)-prelact one B;
YADAV, JS;REDDY, BVS;RAO, K VISHWESHWAR;RAJ, K
SARITA;RAO, P PURUSHOTHAMA;PRASAD, AR; GUNA
SEKAR, D; First example of molecular iodine-cat alyzed
allylat ion and alkynylat ion of cyclic allylic acet at es
YADAV, JS;SRIHARI, P; For mal t ot al syn t hesi s of (-)-
salicylihalamides A and B
Publications
202
YADAV, JS;REDDY, BVS;PADMAVANI, B;GUPTA, MANOJ
KUMAR; Gallium(III) halide-cat alyzed coupling of indoles
w i t h p h en yl acet yl en e: syn t h esi s o f b i s(i n d o l yl )
phenyl et hanes
YADAV, JS;PRAVEEN KUMAR, S;KONDAJI, G;SRINIVASA
RAO, R;NAGAIAH, K; A novel L-proline cat alyzed biginelli
react i on: one-pot synt hesi s of 3,4-di hydropyri mi di n-
2(1H)-ones under solvent free condit ions
YADAV, JS;REDDY, BVS;NAVEEN KUMAR, V;SRINIVASA
RAO, R;NAGAIAH, K; Fi r st examp l e of i oni c l i q ui d s-
p r omot ed d omi no knoevenag el het er o-d i el s-al d er
react ions: A facile synt hesis of pyrano[3,2-c] coumarins
YADAV, JS;REDDY, BVS;REDDY, P NARAYANA; Rh
2
(Oac)
4
i mmob i l i zed i n [ b mi m] PF
6
: a novel and r ecycl ab l e
cat alyt ic syst em for t he cyclopropanat ion of alkenes
Advanced Synt hesis and Cat alysis (2004) 346(1) : 53-
56
YADAV, JS;REDDY, BVS;REDDY, P NARAYANA; Bi (Ot f )3-
[Bmim]PF6: A novel and recyclable cat alyt ic syst em for
t he diast eroselect ive synt hesis of cis-fused pyrano and
f uranobenzopyrans
YADAV, JS;REDDY, BVS;GUPTA, MANOJ KUMAR; Ferric(III)
ch l o r i d e p r o mo t ed ef f i ci en t t h i o cyan at i o n o f
arylalkanes: A facile synt hesis of dit hiocyanat es
YADAV, JS;REDDY, BVS;SRINIVAS, M; A novel and efficient
met hod f or t he synt hesi s of a-Azi doket ones and a-
Ket ot hi ocyanat es
YADAV, JS;REDDY, BVS;REDDY, V SUNITHA;REDDY, K
SRINIVASA;RAMAKRISHNA, KVS; Mont mori l l oni t e KSF-
cat al yzed o n e- p o t syn t h esi s o f h exah yd r o - 1H-
pyrrol o[3,2-c]qui nol i ne deri vat i ves

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Tet rahedron Let t ers (2004) 45(43) : 8015-8018

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