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INDICATION
ADVERSE REACTION
CONTRAINDIC ATION
NURSING CONSIDERATION
Atorvastatin (Lipitor)
Antilipemics
Inhibits HMGCoA reductas e, an early (and rate limiting) step in cholester ol biosynthe sis.
- In patients with clinically evident coronary heart disease, to reduce the risk of nonfatal MI, fatal & nonfatal strokes, angina heart failure, & revascularization procedures
- Adjunct to diet to reduce LDL, total cholesterol, apolipoprotein B, & triglyceride levels & to increase HDL levels in patients with primary hypercholesterolemi a & mixed dyslipidemia
Contraindicated in patients hypersensitive to drug & in those with active liver disease or unexplained persistent elevations of transminase levels.
- Patient should follow a standard cholesterol lowering diet before & during therapy
GU: UTI
- Before treatment, assess patient for underlying causes for hypercholesterolemia & obtain a baseline lipid profile. Obtain periodic liver function test results & lipid levels before starting treatment & at 6 & 12 weeks after initiation, or after an increase in dosage & periodically thereafter
- Use cautiously
- Alone or as adjunct to lipid lowering treatments, such as LDL apheresis, to reduce total & LDL cholesterol in patients with homozygous familial hypercholesterolemi a
Respiratory: bronchitis
Skin: rash - Withhold or stop drug in patients at risk for renal failure caused by rhabdomyolysis resulting from trauma; in serious, acute conditions that suggest myopathy; & in major surgery, severe acute infection, hypotension, uncontrolled seizures, or severe metabolic, endocrine, or electrolyte
disorders.
- Limit use in children to those older than age 9 with homozygous familial hypercholesterol emia
DRUG NAME
MECHANI SM OF ACTION
INDICATION
ADVERSE REACTION
CONTRAINDICA TION
NURSING CONSIDERATION
Citicoline (Somazine)
Neurotonics, Nootropics
Citicoline is an interneuron al communica tion enhancer. It increases the neurotrans mission levels because it favors the synthesis and production speed of dopamine in the striatum, acting
- CVD in acute & recovery phase, symptoms & signs of cerebral insufficiency (dizziness, memory loss, poor concentration, disorientation, recent cranial trauma & their sequelae.)
- Fleeting and discrete hypotension effect, increased parasympathetic affects, low blood pressure
- Citicoline may be taken with or without food. Take it with or between meals.
- Itching or hives, swelling in face or hands, chest tightness, tingling in mouth and throat
- The supplement should not be taken in the late afternoon or at night because it can cause difficulty sleeping.
- Restlessness
- Women who are pregnant or trying to become pregnant should consult with their doctor before taking the supplements. Not enough is known about the use of
- Diarrhea
Parasympathetic hypertonia
Citicoline during pregnancy and breast-feeding. Stay on the safe side and avoid use.
- Low or high blood pressure, Tachycardia - Sleeping troubles or insomnia - Special attention should be paid for administration in the neonate, premature and children.
- Blurred vision
- Chest pains
- Contact the physician immediately if allergic reaction such as hives, rash, or itching, swelling in your face or hands, mouth or throat, chest tightness or trouble breathing are experienced.
will prescribe the correct dosage and the length of time it should be taken for a medical condition. Somazine must not be administered along with medicaments containing meclophenoxate