17R 6H

21R

24R

Polyflux R Dialyzer

All the benefits of Polyflux in a reusable version

Stability of performance
In addition to excellent solute transport characteristics, reprocessed high-flux Polyflux dialyzers resist transmembrane endotoxin passage and attenuate inflammatory markers.1 The Polyflux membrane maintains structural integrity throughout the reuse cycles. It retains the ability to clear large uremic toxins and ensures a predictable Kt/V. Reuse procedures do not alter the Polyflux membrane, but preserve albumin levels and continue to provide protection against endotoxin contamination.1

Enhanced design of Polyflux R

Advanced fiber distribution and geometry
- Homogenous fiber distribution for improved blood and dialysate flows - Designed to meet the demands of reuse

Reuse friendly header design

- Thorough distribution of blood to all fibers - No stagnant areas, reducing clotting potential

Quick and simple to use

- Easy set up, saving staff time - Non-removable headers and waterproof labeling for patient and staff safety - Thorough rinseback - Reduced priming solution volume

Reference: (1) Teehan G et al. Reprocessed (high-flux) Polyflux dialyzers resist transmembrane endotoxin passage and attenuate inflammatory markers. Blood Purif. 2004;22(4):329-37.

Polyflux R Dialyzer
Clearances in vitro
QB (ml/min) Urea Creatinine Phosphate Vitamin B12 KoA UF-coefficient in vitro (ml/h, mmHg) +/-20% Priming volume (ml) Maximum TMP (mmHg) Recommended QB (ml/min) Recommended QD (ml/min) Performance in vitro, after reuse QD=500 ml/min; UF=0 ml/min, clearance in vitro (ml/min) +/- 10%, variation for Vitamin B12 +/-20% measured according to ISO 8637 Hemodialysis (HD) 1 reuse QB (ml/min), UF=0 ml/min Clearance of urea Clearance of creatinine Clearance of vitamin B12 UF-coefficient*(ml/h. mmHg) +/-20% 5 reuses QB (ml/min), UF=0 ml/min Clearance of urea Clearance of creatinine Clearance of vitamin B12 UF-coefficient (ml/h. mmHg) +/-20% 15 reuses QB (ml/min), UF=0 ml/min Clearance of urea Clearance of creatinine Clearance of vitamin B12 UF-coefficient (ml/h. mmHg) +/-20% SPECIFICATIONS Membrane Effective surface area (m2) Fiber dimensions Wall thickness (m) Inner diameter (m) Component Membrane Potting material Housing and caps Sterile plugs Material Polyflux** Polyurethane (PUR) Polycarbonate (PC) Polypropylene (PP)

Clinical data
PERFORMANCES IN VITRO Measured according to EN 1283
Polyflux 17R
200 191 179 176 136 860 300 254 229 223 159 880 71 121 600 200-400 500-800 400 295 260 253 174 890 300 267 245 240 178 1080

(ml/min) +/-10%: QD=500 ml/min and UF=0 ml/min

Polyflux 21R
400 315 282 275 197 1100 83 152 600 200-500 500-800 500 346 308 299 209 1140 300 274 255 249 192 1240

Polyflux 24R
2008 Gambro Lundia AB 306150076 Rev H
Caution: Federal Law (USA) restricts this device to sale, by or on the order of a physician. Read Instructions For Use prior to patient application.

400 326 296 288 214 1260 77 165 600 300-500 500-800

500 360 322 314 229 1300

200 190 179 135

300 253 228 157 57

400 294 258 168

300 264 241 174

400 310 277 191 63

500 341 302 203

300 253 244 177

400 315 290 213 61

500 385 358 229

200 188 174 125

300 249 223 145 54

400 285 251 154

300 258 234 165

400 301 267 181 46

500 330 290 192

300 265 250 186

400 309 283 204 44

500 344 318 205

200 185 170 124

300 248 218 140 52

400 284 245 149

300 255 230 161

400 297 262 176 44

500 325 285 187

300 274 249 177

400 328 294 199 39

500 358 316 213

1.7 50 215 Sieving coefficient in vitro Sterile barrier

2.1 50 215 Sterilization agent Steam

2.4 40 190 Ordering information Polyflux 17R Polyflux 21R Polyflux 24R 16/case 16/case 16/case

Vitamin B12 1.0 Medical grade paper Inulin 0.99 2-Microglobulin 0.63 Albumin <0.01 in vitro according to EN 1283, +/- 20%

* Measured with bovine blood, Hematocrit=32%, Protein 60 g/l at 37C. ** Polyflux is a blend of Polyarylethersulfone, Polyvinylpyrrolidone, Polyamide. These specifications are subject to change without notice. For further information and operating instructions please refer to the Instructions for Use.

For Customer Support, call 800-525-2623

14143 Denver West Parkway, Lakewood, CO 80401

800-525-2623

visit us at www.gambro.com