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Amphetamine

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2006 MeSH

MeSH Descriptor Data


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MeSH Heading Tree Number Annotation

Amphetamine D02.092.471.683.152.110 a specific chem: do not confuse with AMPHETAMINES; d-amphetamine = DEXTROAMPHETAMINE; N-methylamphetamine = METHAMPHETAMINE A powerful central nervous system stimulant and sympathomimetic. Amphetamine has multiple mechanisms of action including blocking uptake of adrenergics and dopamine, stimulation of release of monamines, and inhibiting monoamine oxidase. Amphetamine is also a drug of abuse and a psychotomimetic. The l- and the d,l-forms are included here. The l-form has less central nervous system activity but stronger cardiovascular effects. The d-form is DEXTROAMPHETAMINE. Desoxynorephedrin Levoamphetamine Phenopromin l-Amphetamine Amfetamine Amphetamine Sulfate Amphetamine Sulfate (2:1) Centramina Fenamine Miquel Brand of Amfetamine Sulfate Mydrial Phenamine Thyramine levo-Amphetamine AD AE AG AI AN BL CF CH CL CS CT DU EC HI IM IP ME PD PK PO RE SD ST TO TU UR Adrenergic Agents Adrenergic Uptake Inhibitors Central Nervous System Stimulants Dopamine Agents

Scope Note

Entry Term Entry Term Entry Term Entry Term Entry Term Entry Term Entry Term Entry Term Entry Term Entry Term Entry Term Entry Term Entry Term Entry Term Allowable Qualifiers Pharm. Action Pharm. Action Pharm. Action Pharm.

http://www.nlm.nih.gov/cgi/mesh/2006/MB_cgi?mode=&term=AMPHETAMINE[9/8/2011 11:58:03 PM]

Amphetamine

Action Pharm. Action Pharm. Action CAS Type 1 Name Registry Number Related Number Related Number Dopamine Uptake Inhibitors Sympathomimetics Benzeneethanamine, alpha-methyl-, (+-)300-62-9 60-13-9 (sulfate (2:1)) 60-15-1

Entry analogs & derivatives:Amphetamines Combination Unique ID D000661

MeSH Tree Structures


Organic Chemicals [D02] Amines [D02.092] Ethylamines [D02.092.471] Phenethylamines [D02.092.471.683] Amphetamines [D02.092.471.683.152] Amphetamine [D02.092.471.683.152.110] Dextroamphetamine [D02.092.471.683.152.110.200] p-Chloroamphetamine [D02.092.471.683.152.200] 2,5-Dimethoxy-4-Methylamphetamine [D02.092.471.683.152.391] p-Hydroxyamphetamine [D02.092.471.683.152.500] Iofetamine [D02.092.471.683.152.535] Methamphetamine [D02.092.471.683.152.619] + 3,4-Methylenedioxyamphetamine [D02.092.471.683.152.660] N-Methyl-3,4-methylenedioxyamphetamine [D02.092.471.683.152.670] Phentermine [D02.092.471.683.152.766] + Return to Entry Page Link to NLM Cataloging Classification

http://www.nlm.nih.gov/cgi/mesh/2006/MB_cgi?mode=&term=AMPHETAMINE[9/8/2011 11:58:03 PM]

Amphetamine

http://www.nlm.nih.gov/cgi/mesh/2006/MB_cgi?mode=&term=AMPHETAMINE[9/8/2011 11:58:03 PM]

Amphetamines

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2006 MeSH

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MeSH Heading Tree Number Annotation Scope Note See Also See Also Allowable Qualifiers Registry Number Previous Indexing History Note

Amphetamines D02.092.471.683.152 GEN or unspecified; prefer specifics; do not confuse with AMPHETAMINE, a specific chem; Nmethylamphetamine = METHAMPHETAMINE Analogs or derivatives of AMPHETAMINE. Many are sympathomimetics and central nervous system stimulators causing excitation, vasopressin, bronchodilation, and to varying degrees, anorexia, analepsis, nasal decongestion, and some smooth muscle relaxation. Appetite Depressants Central Nervous System Stimulants AD AE AG AI AN BL CF CH CL CS CT DU EC HI IM IP ME PD PK PO RE SD ST TO TU UR 0 Amphetamine (1966-1975) 76; was NON MESH before 1976

Unique ID D000662

MeSH Tree Structures


Organic Chemicals [D02] Amines [D02.092] Ethylamines [D02.092.471] Phenethylamines [D02.092.471.683] Albuterol [D02.092.471.683.061] Amphetamines [D02.092.471.683.152] Amphetamine [D02.092.471.683.152.110] + p-Chloroamphetamine [D02.092.471.683.152.200] 2,5-Dimethoxy-4-Methylamphetamine [D02.092.471.683.152.391]
http://www.nlm.nih.gov/cgi/mesh/2006/MB_cgi?mode=&term=AMPHETAMINES[9/8/2011 11:58:17 PM]

Amphetamines

p-Hydroxyamphetamine [D02.092.471.683.152.500] Iofetamine [D02.092.471.683.152.535] Methamphetamine [D02.092.471.683.152.619] + 3,4-Methylenedioxyamphetamine [D02.092.471.683.152.660] N-Methyl-3,4-methylenedioxyamphetamine [D02.092.471.683.152.670] Phentermine [D02.092.471.683.152.766] + Butoxamine [D02.092.471.683.221] Dexfenfluramine [D02.092.471.683.338] Dimethoxyphenylethylamine [D02.092.471.683.386] Dobutamine [D02.092.471.683.410] Fendiline [D02.092.471.683.450] Fenfluramine [D02.092.471.683.467] + Hexoprenaline [D02.092.471.683.530] 2-Hydroxyphenethylamine [D02.092.471.683.545] Isoxsuprine [D02.092.471.683.560] Mescaline [D02.092.471.683.635] Methoxamine [D02.092.471.683.661] p-Methoxy-N-methylphenethylamine [D02.092.471.683.670] Nylidrin [D02.092.471.683.715] Octopamine [D02.092.471.683.725] Oxyfedrine [D02.092.471.683.775] Prenylamine [D02.092.471.683.825] Ritodrine [D02.092.471.683.870] Selegiline [D02.092.471.683.915] Suloctidil [D02.092.471.683.934] Verapamil [D02.092.471.683.953] + Return to Entry Page Link to NLM Cataloging Classification

http://www.nlm.nih.gov/cgi/mesh/2006/MB_cgi?mode=&term=AMPHETAMINES[9/8/2011 11:58:17 PM]

Amphetamines

http://www.nlm.nih.gov/cgi/mesh/2006/MB_cgi?mode=&term=AMPHETAMINES[9/8/2011 11:58:17 PM]

Dextroamphetamine

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MeSH Heading Tree Number Scope Note Entry Term Entry Term Entry Term Entry Term Entry Term Entry Term Entry Term Entry Term Entry Term Entry Term Entry Term Entry Term Entry Term

Dextroamphetamine D02.092.471.683.152.110.200 The d-form of AMPHETAMINE. It is a central nervous system stimulant and a sympathomimetic. It has also been used in the treatment of narcolepsy and of attention deficit disorders and hyperactivity in children. Dextroamphetamine has multiple mechanisms of action including blocking uptake of adrenergics and dopamine, stimulating release of monamines, and inhibiting monoamine oxidase. It is also a drug of abuse and a psychotomimetic. d-Amphetamine Celltech Brand of Dextroamphetamine Sulfate Curban Dexamfetamine Dexamphetamine Dexedrine Dextro-Amphetamine Sulfate DextroStat Dextroamphetamine Sulfate GlaxoSmithKline Brand of Dextroamphetamine Sulfate Mallinckrodt Brand of Dextroamphetamine Sulfate Oxydess Pasadena Brand of Dextroamphetamine

http://www.nlm.nih.gov/cgi/mesh/2006/MB_cgi?mode=&term=DEXTROAMPHETAMINE[9/8/2011 11:58:43 PM]

Dextroamphetamine

Entry Term Entry Term Entry Term Entry Term

Shire Brand of Dextroamphetamine Sulfate Vortech Brand of Dextroamphetamine Sulfate d-Amphetamine Sulfate dextro-Amphetamine

Allowable AA AD AE AG AI AN BL CF CH CL CS CT DU EC HI IM IP ME PD PK PO RE SD ST TO TU UR Qualifiers Pharm. Action Pharm. Action Pharm. Action Pharm. Action Pharm. Action Pharm. Action Adrenergic Agents Adrenergic Uptake Inhibitors Central Nervous System Stimulants Dopamine Agents Dopamine Uptake Inhibitors Sympathomimetics

CAS Type Benzeneethanamine, alpha-methyl-, (S)1 Name Registry Number Online Note History Note Unique ID 51-64-9 use DEXTROAMPHETAMINE to search DEXTRO AMPHETAMINE 1966-76 77; was DEXTRO AMPHETAMINE 1963-76 D003913

MeSH Tree Structures


Organic Chemicals [D02] Amines [D02.092] Ethylamines [D02.092.471] Phenethylamines [D02.092.471.683] Amphetamines [D02.092.471.683.152] Amphetamine [D02.092.471.683.152.110]

http://www.nlm.nih.gov/cgi/mesh/2006/MB_cgi?mode=&term=DEXTROAMPHETAMINE[9/8/2011 11:58:43 PM]

Dextroamphetamine

Dextroamphetamine [D02.092.471.683.152.110.200] Return to Entry Page Link to NLM Cataloging Classification

http://www.nlm.nih.gov/cgi/mesh/2006/MB_cgi?mode=&term=DEXTROAMPHETAMINE[9/8/2011 11:58:43 PM]

Methamphetamine

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2006 MeSH

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Methamphetamine D02.092.471.683.152.619 A central nervous system stimulant and sympathomimetic with actions and uses similar to DEXTROAMPHETAMINE. The smokable form is a drug of abuse and is referred to as crank, crystal, crystal meth, ice, and speed.

Annotation a CNS stimulant; smokable crystal methamphetamine, called "ice" by drug abusers, goes here

Entry Term Deoxyephedrine Entry Term Abbott Brand of Methamphetamine Hydrochloride Entry Term Desoxyephedrine Entry Term Desoxyn Entry Term Langly Brand of Methamphetamine Hydrochloride Entry Term Madrine Entry Term Metamfetamine Entry Term Methamphetamine Hydrochloride Entry Term Methylamphetamine Entry Term N-Methylamphetamine Allowable Qualifiers Pharm. Action Pharm. Action Pharm. Action Pharm. Action Pharm. Action Pharm. Action CAS Type 1 Name AA AD AE AG AI AN BL CF CH CL CS CT DU EC HI IM IP ME PD PK PO RE SD ST TO TU UR Adrenergic Agents Adrenergic Uptake Inhibitors Central Nervous System Stimulants Dopamine Agents Dopamine Uptake Inhibitors Sympathomimetics Benzeneethanamine, N,alpha-dimethyl-, (S)-

http://www.nlm.nih.gov/cgi/mesh/2006/MB_cgi?mode=&term=METHAMPHETAMINE[9/8/2011 11:59:17 PM]

Methamphetamine

Registry Number

537-46-2

Unique ID D008694

MeSH Tree Structures


Organic Chemicals [D02] Amines [D02.092] Ethylamines [D02.092.471] Phenethylamines [D02.092.471.683] Amphetamines [D02.092.471.683.152] Amphetamine [D02.092.471.683.152.110] + p-Chloroamphetamine [D02.092.471.683.152.200] 2,5-Dimethoxy-4-Methylamphetamine [D02.092.471.683.152.391] p-Hydroxyamphetamine [D02.092.471.683.152.500] Iofetamine [D02.092.471.683.152.535] Methamphetamine [D02.092.471.683.152.619] Benzphetamine [D02.092.471.683.152.619.307] 3,4-Methylenedioxyamphetamine [D02.092.471.683.152.660] N-Methyl-3,4-methylenedioxyamphetamine [D02.092.471.683.152.670] Phentermine [D02.092.471.683.152.766] + Return to Entry Page Link to NLM Cataloging Classification

http://www.nlm.nih.gov/cgi/mesh/2006/MB_cgi?mode=&term=METHAMPHETAMINE[9/8/2011 11:59:17 PM]

Methamphetamine

http://www.nlm.nih.gov/cgi/mesh/2006/MB_cgi?mode=&term=METHAMPHETAMINE[9/8/2011 11:59:17 PM]

Methamphetamine

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2006 MeSH

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MeSH Heading Tree Number Scope Note

Methamphetamine D02.092.471.683.152.619 A central nervous system stimulant and sympathomimetic with actions and uses similar to DEXTROAMPHETAMINE. The smokable form is a drug of abuse and is referred to as crank, crystal, crystal meth, ice, and speed.

Annotation a CNS stimulant; smokable crystal methamphetamine, called "ice" by drug abusers, goes here

Entry Term Deoxyephedrine Entry Term Abbott Brand of Methamphetamine Hydrochloride Entry Term Desoxyephedrine Entry Term Desoxyn Entry Term Langly Brand of Methamphetamine Hydrochloride Entry Term Madrine Entry Term Metamfetamine Entry Term Methamphetamine Hydrochloride Entry Term Methylamphetamine Entry Term N-Methylamphetamine Allowable Qualifiers Pharm. Action Pharm. Action Pharm. Action Pharm. Action Pharm. Action Pharm. Action CAS Type 1 Name AA AD AE AG AI AN BL CF CH CL CS CT DU EC HI IM IP ME PD PK PO RE SD ST TO TU UR Adrenergic Agents Adrenergic Uptake Inhibitors Central Nervous System Stimulants Dopamine Agents Dopamine Uptake Inhibitors Sympathomimetics Benzeneethanamine, N,alpha-dimethyl-, (S)-

http://www.nlm.nih.gov/cgi/mesh/2006/MB_cgi?mode=&term=Methamphetamine&field=entry[9/9/2011 12:00:07 AM]

Methamphetamine

Registry Number

537-46-2

Unique ID D008694

MeSH Tree Structures


Organic Chemicals [D02] Amines [D02.092] Ethylamines [D02.092.471] Phenethylamines [D02.092.471.683] Amphetamines [D02.092.471.683.152] Amphetamine [D02.092.471.683.152.110] + p-Chloroamphetamine [D02.092.471.683.152.200] 2,5-Dimethoxy-4-Methylamphetamine [D02.092.471.683.152.391] p-Hydroxyamphetamine [D02.092.471.683.152.500] Iofetamine [D02.092.471.683.152.535] Methamphetamine [D02.092.471.683.152.619] Benzphetamine [D02.092.471.683.152.619.307] 3,4-Methylenedioxyamphetamine [D02.092.471.683.152.660] N-Methyl-3,4-methylenedioxyamphetamine [D02.092.471.683.152.670] Phentermine [D02.092.471.683.152.766] + Return to Entry Page Link to NLM Cataloging Classification

http://www.nlm.nih.gov/cgi/mesh/2006/MB_cgi?mode=&term=Methamphetamine&field=entry[9/9/2011 12:00:07 AM]

Methamphetamine

http://www.nlm.nih.gov/cgi/mesh/2006/MB_cgi?mode=&term=Methamphetamine&field=entry[9/9/2011 12:00:07 AM]

Benzphetamine

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MeSH Heading Tree Number Scope Note

Benzphetamine D02.092.471.683.152.619.307 A sympathomimetic agent with properties similar to DEXTROAMPHETAMINE. It is used in the treatment of obesity. (From Martindale, The Extra Pharmacopoeia, 30th ed, p1222)

Entry Term Benzfetamine Entry Term Didrex Entry Term Pharmacia Brand of Benzfetamine Hydrochloride Allowable Qualifiers Pharm. Action Pharm. Action Pharm. Action Pharm. Action Pharm. Action Pharm. Action CAS Type 1 Name Registry Number History Note AA AD AE AG AI AN BL CF CH CL CS CT DU EC HI IM IP ME PD PK PO RE SD ST TO TU UR Adrenergic Agents Adrenergic Uptake Inhibitors Central Nervous System Stimulants Dopamine Agents Dopamine Uptake Inhibitors Sympathomimetics Benzeneethanamine, N,alpha-dimethyl-N-(phenylmethyl)-, (S)156-08-1 91(66); was see under PHENETHYLAMINES 1966-90

Unique ID D001589

MeSH Tree Structures

http://www.nlm.nih.gov/cgi/mesh/2006/MB_cgi?mode=&term=Benzphetamine&field=entry[9/9/2011 12:00:21 AM]

Benzphetamine

Organic Chemicals [D02] Amines [D02.092] Ethylamines [D02.092.471] Phenethylamines [D02.092.471.683] Amphetamines [D02.092.471.683.152] Methamphetamine [D02.092.471.683.152.619] Benzphetamine [D02.092.471.683.152.619.307] Return to Entry Page Link to NLM Cataloging Classification

http://www.nlm.nih.gov/cgi/mesh/2006/MB_cgi?mode=&term=Benzphetamine&field=entry[9/9/2011 12:00:21 AM]

Benzphetamine

http://www.nlm.nih.gov/cgi/mesh/2006/MB_cgi?mode=&term=Benzphetamine&field=entry[9/9/2011 12:00:21 AM]

2,5-Dimethoxy-4-Methylamphetamine

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MeSH Heading Tree Number Scope Note

2,5-Dimethoxy-4-Methylamphetamine D02.092.471.683.152.391 A psychedelic phenyl isopropylamine derivative, commonly called DOM, whose mood-altering effects and mechanism of action may be similar to those of LSD.

Annotation DF: 2 5 DOM

Entry Term 1-(2,5-Dimethoxy-4-Methylphenyl)-2-Aminopropane Entry Term 2 5 DOM Entry Term 2,5-Dimethoxy-4-Methylamphetamine Hydrochloride, (+,-)-Isomer Entry Term 2,5-Dimethoxy-4-Methylamphetamine Hydrochloride, (R)-Isomer Entry Term 2,5-Dimethoxy-4-Methylamphetamine Hydrochloride, (S)-Isomer Entry Term 2,5-Dimethoxy-4-Methylamphetamine, (+,-)-Isomer Entry Term 2,5-Dimethoxy-4-Methylamphetamine, (R)-Isomer Entry Term 2,5-Dimethoxy-4-Methylamphetamine, (S)-Isomer Entry Term 2,5-Dimethoxy-4-Methylamphetamine, Hydrochloride Entry Term DOM Allowable Qualifiers Pharm. Action Pharm. Action AA AD AE AG AI AN BL CF CH CL CS CT DU EC HI IM IP ME PD PK PO RE SD ST TO TU UR Hallucinogens Serotonin Agonists

CAS Type 1 Benzeneethanamine, 2,5-dimethoxy-alpha,4-dimethylName Registry Number Related Number Related Number Related Number 15588-95-1 15589-00-1 (HCl) 26011-50-7 ((+-)-isomer) 29243-80-9 ((+-)-isomer, HCl)

http://www.nlm.nih.gov/cgi/mesh/2006/MB_cgi?mode=&term=2,5-Dimethoxy-4-Methylamphetamine&field=entry[9/9/2011 12:01:01 AM]

2,5-Dimethoxy-4-Methylamphetamine

Related Number Related Number Related Number Related Number History Note Unique ID

43061-13-8 ((R)-isomer) 43061-14-9 ((S)-isomer) 50505-88-9 ((R)-isomer, HCl) 50505-89-0 ((S)-isomer, HCl) 2001(1973) D004290

MeSH Tree Structures


Organic Chemicals [D02] Amines [D02.092] Ethylamines [D02.092.471] Phenethylamines [D02.092.471.683] Amphetamines [D02.092.471.683.152] Amphetamine [D02.092.471.683.152.110] + p-Chloroamphetamine [D02.092.471.683.152.200] 2,5-Dimethoxy-4-Methylamphetamine [D02.092.471.683.152.391] p-Hydroxyamphetamine [D02.092.471.683.152.500] Iofetamine [D02.092.471.683.152.535] Methamphetamine [D02.092.471.683.152.619] + 3,4-Methylenedioxyamphetamine [D02.092.471.683.152.660] N-Methyl-3,4-methylenedioxyamphetamine [D02.092.471.683.152.670] Phentermine [D02.092.471.683.152.766] + Return to Entry Page Link to NLM Cataloging Classification

http://www.nlm.nih.gov/cgi/mesh/2006/MB_cgi?mode=&term=2,5-Dimethoxy-4-Methylamphetamine&field=entry[9/9/2011 12:01:01 AM]

2,5-Dimethoxy-4-Methylamphetamine

http://www.nlm.nih.gov/cgi/mesh/2006/MB_cgi?mode=&term=2,5-Dimethoxy-4-Methylamphetamine&field=entry[9/9/2011 12:01:01 AM]

p-Hydroxyamphetamine

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MeSH Heading Tree Number Scope Note Entry Term Entry Term Entry Term Entry Term Entry Term Entry Term Entry Term Entry Term Entry Term Entry Term Allowable Qualifiers Pharm. Action Pharm. Action CAS Type 1 Name Registry Number Related Number Previous Indexing Previous Indexing History Note

p-Hydroxyamphetamine D02.092.471.683.152.500 Amphetamine metabolite with sympathomimetic effects. It is sometimes called alphamethyltyramine, which may also refer to the meta isomer, gepefrine. Hydroxyphenylisopropylamine Methyltyramine Norpholedrin Oxyamphetamine para-Hydroxyamphetamine Hydroxyamfetamine Hydroxyamphetamin Hydroxyamphetamine Hydroxyamphetamine Hydrobromide Paredrine AA AD AE AG AI AN BL CF CH CL CS CT DU EC HI IM IP ME PD PK PO RE SD ST TO TU UR Mydriatics Sympathomimetics Phenol, 4-(2-aminopropyl)103-86-6 306-21-8 (HBr) Amphetamine (1973-1974) Phenols (1968-1974) 91(75); was see under AMPHETAMINES 1975-90

http://www.nlm.nih.gov/cgi/mesh/2006/MB_cgi?mode=&term=p-Hydroxyamphetamine&field=entry[9/9/2011 12:01:45 AM]

p-Hydroxyamphetamine

Unique ID

D010136

MeSH Tree Structures


Organic Chemicals [D02] Amines [D02.092] Ethylamines [D02.092.471] Phenethylamines [D02.092.471.683] Amphetamines [D02.092.471.683.152] Amphetamine [D02.092.471.683.152.110] + p-Chloroamphetamine [D02.092.471.683.152.200] 2,5-Dimethoxy-4-Methylamphetamine [D02.092.471.683.152.391] p-Hydroxyamphetamine [D02.092.471.683.152.500] Iofetamine [D02.092.471.683.152.535] Methamphetamine [D02.092.471.683.152.619] + 3,4-Methylenedioxyamphetamine [D02.092.471.683.152.660] N-Methyl-3,4-methylenedioxyamphetamine [D02.092.471.683.152.670] Phentermine [D02.092.471.683.152.766] + Return to Entry Page Link to NLM Cataloging Classification

http://www.nlm.nih.gov/cgi/mesh/2006/MB_cgi?mode=&term=p-Hydroxyamphetamine&field=entry[9/9/2011 12:01:45 AM]

p-Hydroxyamphetamine

http://www.nlm.nih.gov/cgi/mesh/2006/MB_cgi?mode=&term=p-Hydroxyamphetamine&field=entry[9/9/2011 12:01:45 AM]

Iofetamine

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2006 MeSH

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MeSH Heading Tree Number Scope Note

Iofetamine D02.092.471.683.152.535 An amphetamine analog that is rapidly taken up by the lungs and from there redistributed primarily to the brain and liver. It is used in brain radionuclide scanning with I-123.

Entry Term Iodine-123-IMP Entry Term N-Isopropyl-p-iodoamphetamine Entry Term Iofetamine Hydrochloride, I-123 Entry Term Iofetamine I-123 Entry Term N-Isopropyl-p-(Iodine-123)-Iodoamphetamine Entry Term N-Isopropyl-p-iodoamphetamine (I123) Hydrochloride Allowable Qualifiers Pharm. Action AA AD AE AG AI AN BL CF CH CL CS CT DU EC HI IM IP ME PD PK PO RE SD ST TO TU UR Radiopharmaceuticals

CAS Type 1 Benzeneethanamine, 4-iodo-alpha-methyl-N-(1-methylethyl)Name Registry Number Related Number Previous Indexing History Note 95896-48-3 85068-76-4 (123I labeled hydrochloride) Amphetamines (1980-1998) 99; use IOFETAMINE (NM) 1980-98

Unique ID D020367

MeSH Tree Structures


Organic Chemicals [D02] Amines [D02.092]
http://www.nlm.nih.gov/cgi/mesh/2006/MB_cgi?mode=&term=Iofetamine&field=entry[9/9/2011 12:02:19 AM]

Iofetamine

Ethylamines [D02.092.471] Phenethylamines [D02.092.471.683] Amphetamines [D02.092.471.683.152] Amphetamine [D02.092.471.683.152.110] + p-Chloroamphetamine [D02.092.471.683.152.200] 2,5-Dimethoxy-4-Methylamphetamine [D02.092.471.683.152.391] p-Hydroxyamphetamine [D02.092.471.683.152.500] Iofetamine [D02.092.471.683.152.535] Methamphetamine [D02.092.471.683.152.619] + 3,4-Methylenedioxyamphetamine [D02.092.471.683.152.660] N-Methyl-3,4-methylenedioxyamphetamine [D02.092.471.683.152.670] Phentermine [D02.092.471.683.152.766] + Return to Entry Page Link to NLM Cataloging Classification

http://www.nlm.nih.gov/cgi/mesh/2006/MB_cgi?mode=&term=Iofetamine&field=entry[9/9/2011 12:02:19 AM]

Iofetamine

http://www.nlm.nih.gov/cgi/mesh/2006/MB_cgi?mode=&term=Iofetamine&field=entry[9/9/2011 12:02:19 AM]

3,4-Methylenedioxyamphetamine

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2006 MeSH

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MeSH Heading Tree Number Scope Note

3,4-Methylenedioxyamphetamine D02.092.471.683.152.660 An amphetamine derivative that inhibits uptake of catecholamine neurotransmitters. It is a hallucinogen. It is less toxic than its methylated derivative but in sufficient doses may still destroy serotonergic neurons and has been used for that purpose experimentally.

Allowable AA AD AE AG AI AN BL CF CH CL CS CT DU EC HI IM IP ME PD PK PO RE SD ST TO TU UR Qualifiers Pharm. Action Pharm. Action Pharm. Action Adrenergic Uptake Inhibitors Hallucinogens Serotonin Agents

CAS Type 1,3-Benzodioxole-5-ethanamine, alpha-methyl1 Name Registry Number 4764-17-4

Previous Amphetamine (1973-1976) Indexing Previous Dioxoles (1974-1975) Indexing Previous Methyl Ethers (1973) Indexing History Note Unique ID 91(77); was see under AMPHETAMINES 1977-90 D015104

MeSH Tree Structures


Organic Chemicals [D02]
http://www.nlm.nih.gov/cgi/mesh/2006/MB_cgi?mode=&term=3,4-Methylenedioxyamphetamine&field=entry[9/9/2011 12:03:04 AM]

3,4-Methylenedioxyamphetamine

Amines [D02.092] Ethylamines [D02.092.471] Phenethylamines [D02.092.471.683] Amphetamines [D02.092.471.683.152] Amphetamine [D02.092.471.683.152.110] + p-Chloroamphetamine [D02.092.471.683.152.200] 2,5-Dimethoxy-4-Methylamphetamine [D02.092.471.683.152.391] p-Hydroxyamphetamine [D02.092.471.683.152.500] Iofetamine [D02.092.471.683.152.535] Methamphetamine [D02.092.471.683.152.619] + 3,4-Methylenedioxyamphetamine [D02.092.471.683.152.660] N-Methyl-3,4-methylenedioxyamphetamine [D02.092.471.683.152.670] Phentermine [D02.092.471.683.152.766] + Return to Entry Page Link to NLM Cataloging Classification

http://www.nlm.nih.gov/cgi/mesh/2006/MB_cgi?mode=&term=3,4-Methylenedioxyamphetamine&field=entry[9/9/2011 12:03:04 AM]

3,4-Methylenedioxyamphetamine

http://www.nlm.nih.gov/cgi/mesh/2006/MB_cgi?mode=&term=3,4-Methylenedioxyamphetamine&field=entry[9/9/2011 12:03:04 AM]

N-Methyl-3,4-methylenedioxyamphetamine

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MeSH Heading Tree Number Scope Note

N-Methyl-3,4-methylenedioxyamphetamine D02.092.471.683.152.670 An N-substituted amphetamine analog. It is a widely abused drug classified as a hallucinogen and causes marked, long-lasting changes in brain serotonergic systems. It is commonly referred to as MDMA or ecstasy.

Annotation street drug Ecstasy goes here; DF: note short X ref

Entry Term MDMA Entry Term Methylenedioxymethamphetamine Entry Term Ecstasy (Drug) Entry Term N-Methyl-3,4-methylenedioxyamphetamine Hydrochloride Allowable Qualifiers Pharm. Action Pharm. Action Pharm. Action CAS Type 1 Name Registry Number Related Number Previous Indexing Online Note History Note AA AD AE AG AI AN BL CF CH CL CS CT DU EC HI IM IP ME PD PK PO RE SD ST TO TU UR Adrenergic Uptake Inhibitors Hallucinogens Serotonin Agents 1,3-Benzodioxole-5-ethanamine, N,alpha-dimethyl42542-10-9 64057-70-1 (HCl) 3,4-Methylenedioxyamphetamine/analogs & derivatives (1984-1994) use N-METHYL-3,4-METHYLENEDIOXYAMPHETAMINE (NM) to search N-METHYL-3,4METHYLENEDIOXYAMPHETAMINE 1984-94 95; was N-METHYL-3,4-METHYLENEDIOXYAMPHETAMINE (NM) 1984-94

Unique ID D018817

http://www.nlm.nih.gov/cgi/mesh/2006/MB_cgi?mode=&term=N-Methyl-3,4-methylenedioxyamphetamine&field=entry[9/9/2011 12:03:25 AM]

N-Methyl-3,4-methylenedioxyamphetamine

MeSH Tree Structures


Organic Chemicals [D02] Amines [D02.092] Ethylamines [D02.092.471] Phenethylamines [D02.092.471.683] Amphetamines [D02.092.471.683.152] Amphetamine [D02.092.471.683.152.110] + p-Chloroamphetamine [D02.092.471.683.152.200] 2,5-Dimethoxy-4-Methylamphetamine [D02.092.471.683.152.391] p-Hydroxyamphetamine [D02.092.471.683.152.500] Iofetamine [D02.092.471.683.152.535] Methamphetamine [D02.092.471.683.152.619] + 3,4-Methylenedioxyamphetamine [D02.092.471.683.152.660] N-Methyl-3,4-methylenedioxyamphetamine [D02.092.471.683.152.670] Phentermine [D02.092.471.683.152.766] + Return to Entry Page Link to NLM Cataloging Classification

http://www.nlm.nih.gov/cgi/mesh/2006/MB_cgi?mode=&term=N-Methyl-3,4-methylenedioxyamphetamine&field=entry[9/9/2011 12:03:25 AM]

N-Methyl-3,4-methylenedioxyamphetamine

http://www.nlm.nih.gov/cgi/mesh/2006/MB_cgi?mode=&term=N-Methyl-3,4-methylenedioxyamphetamine&field=entry[9/9/2011 12:03:25 AM]

Phenethylamines

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2006 MeSH

MeSH Descriptor Data


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MeSH Heading Tree Number Scope Note Allowable Qualifiers Registry Number Online Note History Note Unique ID

Phenethylamines D02.092.471.683 A group of compounds that are derivatives of beta- aminoethylbenzene which is structurally and pharmacologically related to amphetamine. (From Merck Index, 11th ed) AD AE AG AI AN BL CF CH CL CS CT DU EC HI IM IP ME PD PK PO RE SD ST TO TU UR 0 use PHENETHYLAMINES to search PHENYLETHYLAMINES 1966-67 68; was PHENYLETHYLAMINES 1963-67 D010627

Entry Term Phenylethylamines

MeSH Tree Structures


Organic Chemicals [D02] Amines [D02.092] Ethylamines [D02.092.471] Cystamine [D02.092.471.200] Dibenzylchlorethamine [D02.092.471.245] Diethylamines [D02.092.471.302] Diethylpropion [D02.092.471.308] Diphenhydramine [D02.092.471.320] + Histamine [D02.092.471.440] + Mercaptoethylamines [D02.092.471.562] + Orphenadrine [D02.092.471.600] Phenethylamines [D02.092.471.683] Albuterol [D02.092.471.683.061]
http://www.nlm.nih.gov/cgi/mesh/2006/MB_cgi?mode=&term=Phenethylamines&field=entry[9/9/2011 12:04:18 AM]

Phenethylamines

Amphetamines [D02.092.471.683.152] + Butoxamine [D02.092.471.683.221] Dexfenfluramine [D02.092.471.683.338] Dimethoxyphenylethylamine [D02.092.471.683.386] Dobutamine [D02.092.471.683.410] Fendiline [D02.092.471.683.450] Fenfluramine [D02.092.471.683.467] + Hexoprenaline [D02.092.471.683.530] 2-Hydroxyphenethylamine [D02.092.471.683.545] Isoxsuprine [D02.092.471.683.560] Mescaline [D02.092.471.683.635] Methoxamine [D02.092.471.683.661] p-Methoxy-N-methylphenethylamine [D02.092.471.683.670] Nylidrin [D02.092.471.683.715] Octopamine [D02.092.471.683.725] Oxyfedrine [D02.092.471.683.775] Prenylamine [D02.092.471.683.825] Ritodrine [D02.092.471.683.870] Selegiline [D02.092.471.683.915] Suloctidil [D02.092.471.683.934] Verapamil [D02.092.471.683.953] + Phenoxybenzamine [D02.092.471.739] Return to Entry Page Link to NLM Cataloging Classification

http://www.nlm.nih.gov/cgi/mesh/2006/MB_cgi?mode=&term=Phenethylamines&field=entry[9/9/2011 12:04:18 AM]

Phenethylamines

http://www.nlm.nih.gov/cgi/mesh/2006/MB_cgi?mode=&term=Phenethylamines&field=entry[9/9/2011 12:04:18 AM]

Dextroamphetamine

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2006 MeSH

MeSH Descriptor Data


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MeSH Heading Tree Number Scope Note Entry Term Entry Term Entry Term Entry Term Entry Term Entry Term Entry Term Entry Term Entry Term Entry Term Entry Term Entry Term Entry Term

Dextroamphetamine D02.092.471.683.152.110.200 The d-form of AMPHETAMINE. It is a central nervous system stimulant and a sympathomimetic. It has also been used in the treatment of narcolepsy and of attention deficit disorders and hyperactivity in children. Dextroamphetamine has multiple mechanisms of action including blocking uptake of adrenergics and dopamine, stimulating release of monamines, and inhibiting monoamine oxidase. It is also a drug of abuse and a psychotomimetic. d-Amphetamine Celltech Brand of Dextroamphetamine Sulfate Curban Dexamfetamine Dexamphetamine Dexedrine Dextro-Amphetamine Sulfate DextroStat Dextroamphetamine Sulfate GlaxoSmithKline Brand of Dextroamphetamine Sulfate Mallinckrodt Brand of Dextroamphetamine Sulfate Oxydess Pasadena Brand of Dextroamphetamine

http://www.nlm.nih.gov/cgi/mesh/2006/MB_cgi?mode=&term=Dextroamphetamine&field=entry[9/9/2011 12:05:05 AM]

Dextroamphetamine

Entry Term Entry Term Entry Term Entry Term

Shire Brand of Dextroamphetamine Sulfate Vortech Brand of Dextroamphetamine Sulfate d-Amphetamine Sulfate dextro-Amphetamine

Allowable AA AD AE AG AI AN BL CF CH CL CS CT DU EC HI IM IP ME PD PK PO RE SD ST TO TU UR Qualifiers Pharm. Action Pharm. Action Pharm. Action Pharm. Action Pharm. Action Pharm. Action Adrenergic Agents Adrenergic Uptake Inhibitors Central Nervous System Stimulants Dopamine Agents Dopamine Uptake Inhibitors Sympathomimetics

CAS Type Benzeneethanamine, alpha-methyl-, (S)1 Name Registry Number Online Note History Note Unique ID 51-64-9 use DEXTROAMPHETAMINE to search DEXTRO AMPHETAMINE 1966-76 77; was DEXTRO AMPHETAMINE 1963-76 D003913

MeSH Tree Structures


Organic Chemicals [D02] Amines [D02.092] Ethylamines [D02.092.471] Phenethylamines [D02.092.471.683] Amphetamines [D02.092.471.683.152] Amphetamine [D02.092.471.683.152.110]

http://www.nlm.nih.gov/cgi/mesh/2006/MB_cgi?mode=&term=Dextroamphetamine&field=entry[9/9/2011 12:05:05 AM]

Dextroamphetamine

Dextroamphetamine [D02.092.471.683.152.110.200] Return to Entry Page Link to NLM Cataloging Classification

http://www.nlm.nih.gov/cgi/mesh/2006/MB_cgi?mode=&term=Dextroamphetamine&field=entry[9/9/2011 12:05:05 AM]

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