DRUG STUDY Generic name: Galantamine hydrobromide Brand name: Razadyne Classification: Cholinesterase inhibitor, Alzheimers disease drug

Dosage, route and frequency: 4 mg PO bid Mechanism of action: centrally acting, selective, long-acting, reversible cholinesterase inhibitor, causes elevated acetylcholine levels in the cortex, which is thought to slow the neuronal degradation that occurs in Alzheimers disease.

Contraindication: known allergy to drug severe hepatic impairment severe renal impairment Indication:
treat symptoms of mild to moderate Alzheimers disease Adverse effects: insomnia diarrhea dizziness nausea and vomiting headache abdominal pain Nursing Responsibilities Rationale

1. Check the doctors order. 1. Monitor the patients when drug is started.

To avoid committing error. To note the changes that may happen to the patient while taking the drug. To allow evaluation effectiveness. of drug

1. Establish baseline functional profile. 1. Advise the patient to take it with food. 1. Provide small frequent feeding. 1. Provide low fiber diet. 1. Provide calm environment.

To decrease GI discomfort. To minimize nausea and vomiting. To avoid aggravating the condition of the patient. To reduce experiencing of

headache.

Generic name: Donapezil hydrochloride Brand name: Articept Classification: Cholinesterase inhibitor, Alzheimers disease drug Dosage, route and frequency: 5 mg PO daily Mechanism of action: centrally acting, selective, long-acting, reversible cholinesterase inhibitor, causes elevated acetylcholine levels in the cortex, which is thought to slow the neuronal degradation that occurs in Alzheimers disease.

Contraindication: known allergy to donapezil Indication: treatment of dementia of the Alzheimers type, including severe dementia

Adverse effects: insomnia nausea vomiting diarrhea abdominal pain Nursing Responsibilities Rationale

1. Check the doctors order. 1. Monitor the patients when drug is started. 1. Establish baseline functional profile. 1. Advise the patient to take it with food. 1. Provide small frequent feeding. 1. Provide low fiber diet.

To avoid committing error. To note the changes that may happen to the patient while taking the drug. To allow evaluation effectiveness. of drug

To decrease GI discomfort. To minimize nausea and vomiting. To avoid aggravating the condition

of the patient. 1. Provide calm environment. To reduce headache. experiencing of