Int. J. Morphol., 28(2):405-408, 2010.

Anatomical Study of the Pterygospinous and Pterygoalar Bony Bridges and Foramens in Dried Crania and its Clinical Relevance
Estudio Anatmico de los Puentes seos y Formenes Pterigoespinoso y Pterigoalar en Crneos Secos y su Relevancia Clnica

Ivn Suazo Galdames; **Daniela Zavando Matamala & ***Ricardo Luiz Smith

SUAZO, G. I.; ZAVANDO, M. D.; SMITH, R. L. Anatomical study of the pterygospinous and pterygoalar bony bridges and foramens in dried crania and its clinical relevance. Int. J. Morphol., 28(2):405-408, 2010. SUMMARY: The ossification of the intrinsic ligaments of the sphenoid bone has been reported in the literature. The presence of bony bridges by ossification of the pterygospinous and pterygoalar ligaments has clinical significance in the infratemporal fossa contents. The purpose of this study is to analyze the prevalence of ossification of these ligaments and assess morphometrically the pterygospinous (Civininis) and pterygoalar (crotaphitico-buccinatorius) foramens. A total of 312 human skulls from the collection of Universidade Federal de So Paulo (UNIFESP) were used to assess the presence of total or partial ossification in pterygospinous (Types I and II) and pterygoalar (Types III and IV) ligaments. Of the sample, 37.18% had some degree of ossification; in Type I, ossification was found in 1.6%, while Types II, III and IV had 13.14, 3.84, and 22.43%, respectively. The pterygospinous foramen presented an average diameter between 10.6267.366 mm, whereas for the pterygoalar foramen it was between 5.2023.793 mm. The presence of these formations must be considered in the therapeutic procedures that are performed in the infratemporal region, in assessing pain affecting the territory innervated by the mandibular nerve. KEYWORDS: Pterygospinous ligament; Pterygoalar ligament; Infratemporal fossa; Foramen ovale; Porus crotaphiticobuccinatorius.

INTRODUCTION

The presence of ossification in the pterygospinous and pterygoalar ligaments have clinical significance as these ligaments establish relationships with the oval foramen and because of the effects that emerge from it, such as increasing difficulty in accessing the oval foramen in a therapeutic approach. In terms of its prevalence, Nayak et al. (2007) analyzed 416 Indian dried skulls; 9.61% of the samples presented the pterygospinous bony bridges, of which 5.76% was complete and 3.84% was incomplete. On the other hand, Kapur et al. (2000) in an earlier study obtained a lower prevalence of 1.31% of complete pterygospinous ligament ossification, from a sample of 305 Croats skulls. The pterygospinous ligament described by Civinini in 1835 (cited
* **

by Tebo, 1968) is directed from the spine of the sphenoid bone to the pterygospinous process when ossified, establishing the pterygospinous foramen. Rouvire & Delmas (1999) stated that the pterygospinous ligament divides the sphenomandibular ligament into two independent, of which the interpterygoid fascia is thin. Lateral to the interpterygoid fascia is another fibrous plate inserted in the greater wing of the sphenoid and in the superior segment of the posterior edge of lateral plate in the pterygoid process. Its superior edge becomes flat and forms an innominated ligament, described by Hyrtl in 1862 (Cited by Tebo), and posteriorly called pterygoalar ligament (Antonopoulou et al., 2008) which when it is ossified, mold the pterygoalar foramen (porus crotaphitico-buccinatorius).

Universidad de Talca, Chile. Universidad Autnoma de Chile, Chile. *** Department of Morphology and Genetic. Universidade Federal de So Paulo, Brazil.

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SUAZO, G. I.; ZAVANDO, M. D.; SMITH, R. L. Anatomical study of the pterygospinous and pterygoalar bony bridges and foramens in dried crania and its clinical relevance. Int. J. Morphol., 28(2):405-408, 2010.

These formations are related laterally with the oval foramen, from which the mandibular nerve emerges, and then enters in the infratemporal fossa. In this position, the mandibular nerve can be compressed as a result of the pterygoid muscle contraction causing pain (Krmpotic-Nemanic et al., 1999). Peuker et al. (2001) described a case in which the lingual nerve was trapped between the pterygospinous bony bridge and the medial pterygoid muscle; this variation is associated with pain and alterations in speech. It is known that the pterygospinous and pterygoalar bony bridges are of great importance to the anesthetic treatment of the mandibular nerve and for therapeutics for the trigeminal ganglion (Das & Paul, 2007; Singh et al., 1993), because their presence hinders access to the needle in the vicinity of the oval foramen. The purpose of this study was to determine the prevalence of pterygospinous and pterygoalar bony bridges and to analyze morphometricaly the homonyms foramen in a collection of contemporary skulls and discuss their clinical implications.

posterior edge of the lateral lamina of the pterygoid process and a process that emerges from the anterolateral area of the base of sphenoid spine. In this case, it is the pterygoalar foramen (crotaphiticobuccinatorius) (Fig. 3).

Fig. 1. Type I presented complete ossification of pterygospinous ligament. In this case, it is the pterygospinous or Civininis foramen. CF: Civinini foramen, SphS: Sphenoid spine.

MATERIAL AND METHOD

By nonprobability convenience sampling, 312 dry human skulls belonging to the collection of the UNIFESP with records of sex, age, and origin were selected. The ages of individuals up to the dates of death was between 18 and 100 years old, the average age of the sample was 42.32 (SD 14.842). Of the total sample, 212 (67.9%) were male skulls, whereas female skulls were 100 (32.1%). Of the 312 skulls, 284 represent Brazilians individuals, which constitute 91% of the group. The remaining 9% (n = 28) is distributed among 11 other nationalities. Skulls that showed visible evidence of abnormalities such as trauma or obvious morphological asymmetries were excluded from this study. The skulls were examined by one observer, in groups of 40 skulls and those that had complete or partial ossification of the pterygospinous and pterygoalar ligaments were identified. The following descriptions are given for ossification of the two ligaments: Type I: presented complete ossification of pterygospinous ligament: there is a bony bridge that leads from the pterygospinous process to the apex of the sphenoid spine. In this case, it is the pterygospinous foramen (Fig. 1). Type II: presented incomplete ossification of pterygospinous ligament: there is a lengthening of the pterygospinous process, but fails to contact the sphenoid spine. In this case, the pterygospinous foramen is partially formed (Fig. 2). Type III: presented complete ossification of pterygoalar ligament: there is a bony bridge between the superior segment of the

Fig. 2. Type II, incomplete ossification of pterygospinous ligament, there is a lengthening of the pterygospinous process. PtsP: Pterygospinous process, SphS: Sphenoid spine.

Type IV: presented incomplete ossification of pterygoalar ligament: there is an elongation of a process in spina shape that originates from the anterolateral area of the sphenoid spine base, but that does not reach sufficiently elongation to contact with the lateral lamina of the pterygoid process. This was an inclusion criteria for considering the elongated process that emerges from the sphenoid spine. It is a fact that in the lateral norma, at least half the foramen ovale is hidden (Fig. 4). In cases where there was complete ossification of the ligaments (Type I and III), the maximum and minimum diameter of the pterygospinous foramen and pterygoalar foramen were determined.

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SUAZO, G. I.; ZAVANDO, M. D.; SMITH, R. L. Anatomical study of the pterygospinous and pterygoalar bony bridges and foramens in dried crania and its clinical relevance. Int. J. Morphol., 28(2):405-408, 2010.

With the data obtained, prevalence rates for the four proposed types were estimated, differentiating the bilateral, right, and left presentations.

of 312 human dry skulls from the UNIFESP collection, the cases distribution of partial and complete pterygospinous and pterygoalar ligaments ossification are presented in Table I. Of the total sample, only five (1.6%) present complete ossification of the pterygospinous ligament, constituting the foramen of the same name (Civininis foramen) (Fig. 1). The maximum diameter of this foramen was 10.626 mm (SD 2.85) and the average minimum diameter was 7.366 mm (SD 1.29). The complete ossification of pterygoalar ligament was found in 12 cases (3.84%), which presents the formation of the pterygoalar foramen (crotaphiticobuccinatorius foramen) (Fig.3), whose maximum diameter was 5.202 mm (SD 1.005) and the minimum diameter was 3.793 mm (SD 1.54).

DISCUSSION
Fig. 3. Type III, complete ossification of pterygoalar ligament. In this case, it is the pterygoalar or crotaphiticobuccinatorius foramen. Cr-Bu: Crotaphitico-buccinatorius (white arrow).

The sphenoid bone presents a series of intrinsic ligaments: interclinoid, caroticoclinoid, pterygospinosus, and pterygoalar ligaments. Ossification process with different clinical implications has been reported for all. The present study analyzed the presence of total or partial pterygospinosus and pterygoalar ligaments ossification. These formations occupy a deep and high portion in the infratemporal fossa establishing important relationships with the mandibular nerve and its branches, the otic ganglion, the median meningeal artery and vein, the tympanic nerve, the medial and lateral pterygoideus muscles. These are compressed against the bone formations and are capable of generating clinically important alterations (Krmpotic-Nemanic et al.; Peuker et al.; von Ldinghausen et al., 2006).

Fig. 4. Type IV, incomplete ossification of pterygoalar ligament: there is an elongation of a process in spina shape that originates from the anterolateral area of the sphenoid spine base. PtaP: Pterygoalar process (white arrow).

RESULTS A total of 116 skulls (37.18%) had some kind of the variation; the most frequent was incomplete ossification of pterygoalar ligament. From the samples

The prevalence of pterygospinosus bony bridges has been reported by different authors with different results. For a sample, WoodJones (1931) reported an 8% pterygospinosus ligament ossification in Hawaiian skulls. Nayak et al. indicated that such bridges was completely ossified in 5.76% of the cases analyzed by them. Peker et al. (2002) reported the presence of this bridge in 8.8% in skulls of an Anatolian population. In this study, the prevalence of complete pterygospinosus ligament ossification was only 1.6%, much lower than those reported in the earlier studies. This could be attributed to the age of this sample (average 42.32 years), as the emergence of ossification process is associated with increasing age of subjects (Cammisa et al., 1998).

Type I n Bilateral Right Left Total 0 2 3 5 % 0.00 0.64 0.96 1.60 n 16 35 22 41

Type II % 5.12 11.21 7.05 13.14 n 4 8 8 12

Type III % 1.28 2.56 2.56 3.84 n 24 38 56 70

Type IV % 7.69 12.17 17.94 22.43

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SUAZO, G. I.; ZAVANDO, M. D.; SMITH, R. L. Anatomical study of the pterygospinous and pterygoalar bony bridges and foramens in dried crania and its clinical relevance. Int. J. Morphol., 28(2):405-408, 2010.

Most cited investigations related to the pterygospinosus ligament ossification and the formation of the homonym foramen did not mention the implications of these variations; however, from a clinical point of view the presence of ossification in the pterygoalar ligament is even more important for two reasons: (i) when pterygoalar ligament is partially ossified the bony prominence not mentioned in anatomical nomenclature, is projected anterolaterally to be a spine that partially covers the access to the oval foramen from a lateral

approach through the supra and the infrazygomatic via, decreasing the effectiveness of extraoral anesthetic treatment technique of the mandibular nerve; (ii) the complete ossification of the pterygoalar ligament determines the formation of the pterygoalar foramen (crotaphitico-buccinatorius), which is much smaller in diameter compared with the pterygospinosus foramen (Civininis). The pterygoalar ligament completely prevents access to the mandibular nerve or trigeminal ganglion from foramen ovale by the supra or infrazygomatic via.

SUAZO, G. I.; ZAVANDO, M. D.; SMITH, R. L. Estudio anatmico de los puentes seos y formenes pterigoespinoso y Pterigoalar en crneos secos y su relevancia clnica. Int. J. Morphol., 28(2):405-408, 2010.
RESUMEN: La osificacin de los ligamentos intrnsecos del hueso esfenoides ha sido reportada en la literatura. La presencia de puentes seos por osificacin de los ligamentos pterigoespinoso y pterigoalar tiene importancia clnica debido a las relaciones que stas formaciones establecen con el contenido de la fosa infratemporal. El propsito de este estudio fue analizar la prevalencia de la osificacin de estos ligamentos y evaluar morfomtricamente los formenes pterigoespinoso (Cinivini's) y pterigoalar (crotaphitico-buccinatorius). Se utilizaron 312 crneos humanos de la coleccin de la UNIFESP, se evalu la presencia de osificacin total o parcial de los ligamentos pterigoespinoso (Tipos I y II) y pterigoalar (Tipos III y IV). Un 37,18 % de la muestra present algn grado de osificacin, el tipo I se encontr en un 1,6%%, el tipo II en un 13,14%, el tipo III en un 3,84% % y el tipo IV en un 22,43%. El foramen pterigoespinoso present un dimetro medio de entre 10,626 7,366 mm, mientras que para el foramen pterigoalar estuvieron entre 5,202 3,793 mm. La presencia de estas formaciones debe ser considerada en los procedimientos teraputicos que se realicen en la regin infratemporal y en la evaluacin de cuadros dolorosos que afectan al territorio inervado por el nervio mandibular. PALABRAS CLAVE: Ligamento Pterigoespinoso; Ligamento Pterigoalar; Fosa infratemporal; Foramen oval; Foramen crotaphiticobuccinatorius.

REFERENCES

Peuker, E. T.; Fischer, G. & Filler, T. J. Entrapment of the lingual nerve due to an ossifed pterygospinous ligament. Clin. Anat. 14(4):282-4, 2001. Rouviere, H. & Delmas, A. Anatoma Humana Descriptiva, Topogrfica y Funcional. Barcelona, Masson, 1999. V. 3. Singh, B.; Srivastava, S. K.; Dang, R.; Gombar, K. K. & Gombar, S. Anatomic considerations in relation to the mandibular nerve block. Reg. Anesth., 18(3):181-3, 1993. Tebo, H. G. The pterygospinous bar in panoramic roentgenography. Oral Surg. Oral Med. Oral Pathol., 26(5):654-7, 1968. Von Ldinghausen, M.; Kageyama, I.; Miura, M. & Alkhatib, M. Morphological peculiarities of the deepinfratemporal fossa in advanced age Morphological peculiarities of the deep infratemporal fossa in advanced age. Surg. Radiol. Anat., 28(3):284-92, 2006. Wood-Jones, F. The non-metrical Morphological Characters of the Skull as Criteria for Racial Diagnosis: Part II: The non-metrical Morphological Characters of the Hawaiian Skull. J. Anat., 65(3):368-78, 1931. Correspondence to: Prof. Dr. Ivn Suazo Galdames Department of Normal Anatomy Avenida Lircay s/n oficina N 104 Universidad de Talca, CHILE Email: isuazo@utalca.cl Received: 09-04-2009 Accepted: 22-01-2010

Antonopoulou, M.; Piagou, M. & Anagnostopoulou, S. An anatomical study of the pterygospinous and pterygoalar bars and foramina their clinical relevance. J. Craniomaxillofac. Surg., 36(2):1048, 2008. Cammisa, M.; De Serio, A. & Guglielmi, G. Diffuse idiopathic skeletal hyperostosis. Eur. J. Radiol., 27(1):S711, 1998. Das, S. & Paul, S. Ossified pterygospinous ligament and its clinical implications. Bratisl. Lek. Listy, 108(3):141-3, 2007. Kapur, E.; Dilberovic, F.; Redzepagic, S. & Berhamovic, E. Variation in the lateral plate of the pterygoid process and the lateral subzygomatic approach to the mandibular nerve. Med. Arh., 54(3):133-7, 2000. Krmpotic-Nemanic, J.; Vinter, I.; Hat, J. & Jalsovec, D. Mandibular neuralgia due to anatomical variations. Eur. Arch. Otorhinolaryngol., 256(4):205-8, 1999. Nayak, S. R.; Saralaya, V.; Prabhu, L. V.; Pai, M. M.; Vadgaonkar, R. & D'Costa, S. Pterygospinous bar and foramina in Indian skulls: incidence and phylogenetic significance. Surg. Radiol. Anat., 29(1):5-7, 2007. Peker, T.; Karakose, M.; Anil, A.; Turgut, H. B. & Gulekon, N. The incidence of basal sphenoid bony bridges in dried crania and cadavers; their anthropological and clinical relevance. Eur. J. Morphol., 40(3):171-80, 2002.

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