1. Burrows, S.R., Elkington, R.A., Miles, J.J., Green, K.J., Walker, S., Haryana, S.M.

,
Moss, D.J., Dunckley, H., Burrows, J.M. and Khanna R. 2003. Promiscuous CTL
recognition of viral epitopes on multiple human leukocyte antigens: biological
validation of the proposed HLA A24 supertype. J. Immunol. 171: 1407-1412

2. Miles, J.J.,* Green, K.J.,* Tellam, J., van Zuylen, W.J.M.,Connolly, G. and Burrows,
S.R. 2004. Potent T cell response to a class-I-binding 13-mer viral epitope and the
influence of HLA micropolymorphism in controlling epitope length. Eur. J.
Immunol. 34(9): 2510-2519

3. Tellam, J., Connolly, G., Green, K.J., Miles, J.J., Moss, D.J., Khanna, R. and
Burrows, S.R. 2004. Endogenous presentation of CD8+ T cell epitopes from Epstein-
Barr virus encoded nuclear antigen 1. J. Exp. Med. 199: 1421-1431

(This article was featured on the cover and was the subject of a commentary in Nat
Immunol 2004 6(7):693 and J. Exp. Med.: C. Munz, Epstein-Barr virus nuclear
antigen 1: from immunologically invisible to a promising T cell target. J. Exp. Med.
2004. 199: 1301-1304

4. Lew A.E., Bock R.E., Miles J.J., Cuttell. L.B., Steer. P., and Nadin-Davis. S.A. 2004.
Sensitive and specific detection of bovine immunodeficiency virus and bovine
syncytial virus by 5' Taq nuclease assays with fluorescent 3' minor groove binder-
DNA probes. J. Virol. Methods. 1;116(1): 1-9

5. Borg N.A., Ely L.K., Beddoe T., Macdonald W.A., Reid H.H., Clements C.S., Purcell
A.W., Kjer-Nielsen L., Miles J.J., Burrows S.R., McCluskey J., and Rossjohn J. 2005
The CDR3 regions of an immunodominant T cell receptor dictate the 'energetic
landscape' of peptide-MHC recognition. Nat. Immunol. 6(2): 171-180

(This article was the subject of a commentary in Nature Immunology 2005 6(2): 130-
132)
6. Ely, L.K., Green, K.J., Beddoe, T., Clements, C.S., Miles, J.J., Bottomley, S.P., Kjer-
Nielsen, L., Purcell, A.W., McCluskey, J., Rossjohn, J. and Burrows, S.R. 2005.
Antagonism of antiviral and allogeneic activity of a human public CTL clonotype by
a single altered peptide ligand: implications for allograft rejection. J. Immunol.
174(9): 5593-5601

7. Tynan, F.E., Borg, N.A., Miles, J.J., Beddoe, T., Elhassen, D., Silins, S.L., van
Zuylen, W.J.M., Purcell, A.W., Kjer-Nielsen, L., McCluskey, J., Burrows, S.R., and
Rossjohn, J. 2005. T cell receptor immunodominance directed towards a highly
bulged viral epitope. J. Biol. Chem. 280(25): 23900-23909

(This article was featured on the cover of J Biol Chem, issue 280[25])

8. Miles, J.J.,* Borg, N.A.,* Elhassen, D., Silins, S.L., Tynan, F.E., Burrows, J.M.,
Purcell, A.W., Kjer-Nielsen, L., Rossjohn, J., Burrows, S.R., and McCluskey, J. 2005.
CTL Recognition of a Bulged Viral Peptide Involves Biased TCR Selection. J.
Immunol. 175(6): 3826-3834

9. Tynan, F.E., Burrows, S.R., Bucle. A.M., Clements, C.S., Borg, N.A., Miles, J.J.,
Beddoe, T., Whisstock, J.C., Wilce, M.C., Silins, S.L., Burrows, J.M., Kjer-Nielsen,
L., Kostenko, L., Purcell, A.W., Rossjohn, J., and McCluskey, J. 2005. T cell receptor
recognition of a super-bulged MHC-class I bound peptide. Nat. Immunol. 6: 1114-
1122

10. Tynan, F.E., Elhassen, D., Burrows. J.M., Miles, J.J., Borg, N.A., Green, K.J.,
Tellam. J., Purcell, A.W., Kjer-Nielsen, L., McCluskey. J., Rossjohn, J., and Burrows,
S.R. 2005. The immunogenicity of a viral cytotoxic T cell epitope is controlled by its
MHC-bound conformation. J. Exp. Med. 202(9): 1249-1260

11. Miles, J.J., Silins S.L., Brooks A.G., Davis J.E., Misko, I., and Burrows S.R. 2005. T
cell grit: large clonal expansions of virus-specific CD8+ T cells can dominate in the
peripheral circulation for at least 18 years. Blood. 106(13): 4412-4413
12. Miles, J.J.,* Borg, N.A.,* Brennan, R.M., Tynan, F.E., Kjer-Nielsen, L., Silins, S.L.,
Bell, M.J., Burrows, J.M., McCluskey, J., Rossjohn, J., and Burrows, S.R., 2006. The
role of T cell receptor alpha genes in directing human MHC restriction. J. Immunol.
15; 177(10): 6804-6814

13. Miles, J.J., Silins S.L., and Burrows S.R. 2006. Engineered T cell receptors and their
potential in molecular medicine. Current. Med. Chem. 13(23): 2725-2736

14. Archbold J.K., Macdonald W.A., Miles J.J., Brennan R.M., Kjer-Nielsen L.,
McCluskey J., Burrows S.R., Rossjohn J. 2006. Alloreactivity between disparate
cognate and allogeneic pMHC-I complexes is the result of highly focused, peptide-
dependent structural mimicry. J. Biol. Chem. 10;281(45): 34324-34332

15. Tynan F.E., Reid H.H., Kjer-Nielsen L., Miles J.J., Wilce M.C., Kostenko L., Borg
N.A., Williamson N.A., Beddoe T., Purcell A.W., Burrows S.R., McCluskey J.,
Rossjohn J. 2007. A T cell receptor flattens a bulged antigenic peptide presented by a
major histocompatibility complex class I molecule. Nat. Immunol. 8(3): 268-276

16. Burrows, J.M., Wynn, K.K., Tynan, F.E., Archbold, J., Miles, J.J., Bell, M.J.,
Brennan, R.M., Walker, S., McCluskey, J., Rossjohn, J., Khanna, R., and Burrows,
S.R. 2007. The impact of HLA micropolymorphism outside primary peptide anchor
pockets on the CTL response to CMV. Eur. J. Immunol. 37(4): 946-953

17. Miles, J.J.,* Brennan, R.M.,* Silins S.L., Burrows, J.M., Bell, M.J., Burrows, J.M.,
and Burrows, S.R. 2007. Predictable αβ T-Cell Receptor Selection towards a HLA-
B*3501-resticted pp65-derived HCMV antigen. J. Virol. 81(13): 7269-7273

18. Burrows, J.M., Bell, M.J., Brennan, R.M., Miles, J.J., Khanna, R., and Burrows, S.R.
2008. Preferential binding of unusually long peptides to MHC class I and its influence
on the selection of target peptides for T cell recognition. Mol. Immunol. 45(6): 1818-
24

19. Miles, J.J.,* Elliott, S.L., Suhrbier, A., Lawrence, G., Pye, S.J., Le, T, T.,
Rosenstengel, A., Nguyen, T, Allworth, A., Burrows, S.R., Cox, J., Pye, D., Moss,
 D.J., Bharadwaj, M. 2008. A Phase I trial of a CD8+ T Cell Peptide Epitope-based
Vaccine for Infectious Mononucleosis. J. Virol. 82(3): 1448-57

20. Wynn, K.K., Fulton, Z., Cooper, L., Silins, S.L., Gras, S., Archbold, J.K., Tynan,
F.E., Miles, J.J., McCluskey, J., Burrows, S.R., Rossjohn, J., Khanna, R. 2008
Impact of clonal competition for peptide-MHC complexes on the CD8+ T-cell
repertoire selection in a persistent viral infection. Blood. 111(8): 4283-4292

21. Bell, M.J., Brennan, R.M., Miles, J.J., Burrows, J.M., Moss, D.J., and Burrows, S.R.
2008. Widespread Sequence Variation in Epstein-Barr Nuclear Antigen 1 Influences
the Antiviral T cell Response. J. Infect. Dis. 197(11): 1594-1597

22. Archbold, J.K., Macdonald, W.A., Gras, S., Theodossis, A., Ely, L.K., Miles, J.J.,
Bell, M.J., Brennan, R.M., Beddoe, T., Reid, H.H., Wilce, M.C.J., Clements, C.S.,
Purcell, A.W., McCluskey J., Burrows S.R., and Rossjohn J. Natural
micropolymorphism in human leukocyte antigens provides a basis for genetic control
of antigen recognition. J. Exp. Med. 206(1): 209-219 2009)

23. Miles, J.J., Brennan, R.M., and Burrows, S.R. 2009. T cell receptor bias in humans.
Current Immunology Reviews. 5(1): 10-21

24. Bell, M.J., Burrows, J.M., Brennan, R.M., Miles, J.J., Tellam. J., McCluskey J.,
Rossjohn J., Khanna, R., and Burrows, S.R. 2009. The peptide length specificity of
some HLA class I alleles is very broad and includes peptides of up to 25 amino acids
in length. Mol Immunol. 46(8-9): 1911-1917

25. Cole, D.K., Yuan, F., Rizkallah, P.J., Miles, J.J., Gostick, E., Price, D.A., Gao, G.F.,
Jakobsen, B.K., and Sewell, A.K., 2009. Germ line-governed recognition of a cancer
epitope by an immunodominant human T-cell receptor. J Biol Chem. 2;284(40):
27281-27289

26. Wooldridge L., Clement M., Lissina A., Edwards E.S., Ladell K., Ekeruche J., Hewitt
R.E., Laugel B., Gostick E., Cole D.K., Debets R., Berrevoets C., Miles J.J., Burrows
S.R., Price D.A., and Sewell A.K. 2010. MHC class I molecules with Superenhanced
 CD8 binding properties bypass the requirement for cognate TCR recognition and
nonspecifically activate CTLs. J Immunol. 1;184(7): 3357-3366

27. Burrows S.R., Chen Z., Archbold J.K., Tynan F.E., Beddoe T., Kjer-Nielsen L., Miles
J.J., Khanna R., Moss D.J., Liu Y.C., Gras S., Kostenko L., Brennan R.M., Clements
C.S., Brooks A.G., Purcell A.W., McCluskey J., and Rossjohn J. 2010. Hard wiring of
T cell receptor specificity for the major histocompatibility complex is underpinned by
TCR adaptability. Proc. Natl. Acad. Sci. USA. 8;107(23): 10608-10613

28. Gras S., Chen Z., Miles J.J., Liu Y.C., Bell M.J., Sullivan L.C., Kjer-Nielsen L.,
Brennan R.M., Burrows J.M., Neller M.A., Khanna R., Purcell A.W., Brooks A.G.,
McCluskey J., Rossjohn J., and Burrows S.R. 2010. Allelic polymorphism in the T
cell receptor and its impact on immune responses. J. Exp. Med. 5;208(7): 1555-1567

29. Cole D.K., Edwards E.S., Wynn K., Clement M., Miles J.J., Ladell K., Ekeruche J.,
Gostick E., Adams K., Skowera A., Peakman M., Wooldridge L., Price D.A., and
Sewell A.K., 2010. Modification of MHC anchor residues generates heteroclitic
peptides that alter TCR binding and T cell recognition. J. Immunol. 185(4): 2600-
2610

30. Tarbe M., Azcune I., Balentová E., Miles J.J., Edwards E.E., Miles K.M., Do P.,
Baker B.M., Sewell A.K., Aizpurua J.M., Douat-Casassus C., and Quideau S. 2010.
Design, synthesis and evaluation of β-lactam antigenic peptide hybrids; unusual
opening of the β-lactam ring in acidic media. Org. Biomol. Chem. 8(23): 5345-5353

31. Miles J.J., Bulek A.M., Cole D.K., Gostick E., Schauenburg A.J., Dolton G., Venturi
V., Davenport M.P., Tan M.P., Burrows S.R., Wooldridge L., Price D.A., Rizkallah
P.J., and Sewell A.K. 2010. Genetic and structural basis for selection of a ubiquitous
T cell receptor deployed in Epstein-Barr virus infection. PLoS Pathog. 18;6(11)

32. Miles K.M., Miles J.J., Madura F., Sewell A.K., and Cole D.K. 2011. Real time
detection of peptide-MHC dissociation reveals that improvement of primary MHC-
binding residues can have a minimal, or no, effect on stability. Mol. Immunol. 48(4):
728-732
33. Miles J.J., Thammanichanond D., Moneer S., Nivarthi U.K., Kjer-Nielsen L., Tracy
S.L., Aitken C.K., Brennan R.M., Zeng W., Marquart L., Jackson D., Burrows S.R.,
Bowden D.S., Torresi J., Hellard M., Rossjohn J., McCluskey J., and Bharadwaj M.
2011. Antigen-Driven Patterns of TCR Bias Are Shared across Diverse Outcomes of
Human Hepatitis C Virus Infection. J. Immunol. 15;186(2): 901-912

34. Miles J.J., Douek, C.D., and Price D.A., 2011. Bias in the αβ T cell repertoire:
implications for disease pathogenesis and vaccination. Immunol. Cell. Biol.
89(3):375-387

35. Clement M., Ladell K., Ekeruche-Makinde, J., Miles J,J., Edwards E,S., Dolton G.,
Williams T., Schauenburg A,J., Cole D,K., Lauder S,N., Gallimore A,M., Godkin
A,J., Burrows S,R., Price D,A., Sewell A,K., Wooldridge L. 2011. Anti-CD8
Antibodies Can Trigger CD8+ T Cell Effector Function in the Absence of TCR
Engagement and Improve Peptide-MHCI Tetramer Staining. J. Immunol. 15;187(2):
654-663

36. Miles J.J.,* Smith C. and Khanna R., 2011. Advances in T cell alloreactivity;
function, avidity, biophysics and structure. Am. J. Transplant. (In Press)

37. Wooldridge L., Ekeruche-Makinde, J., van den Berg H, A., Skower, A., Miles J.J.,
Ping Tan M., Dolton D., Llewellyn-Lacey S., Price D,A., Peakman M. and Sewell,
A.K. 2011. A single autoimmune T cell receptor recognizes over a million different
peptides. J. Biol. Chem. (In press)

38. Bridgeman J., Sewell A.K., Miles, J.J., Price D.A. and Cole D.K. 2012. Structural
and biophysical determinants of αβ T-cell antigen recognition. Immunology. 135(1);
9-18

39. Bulek A.M., Cole D.K., Skowera A., Dolton G., Gras S., Madura F., Fuller A., Miles
J.J., Gostick E., Price D.A., Drijfhout J., Knight R.R., Lissin N., Molloy., Jakobsen
B.K., Rossjohn J., Peakman M., Rizkallah P.J and Sewell A.K. 2011. Structural basis
 of human β-cell killing by preproinsulin-specific CD8+ T-cells in Type 1 diabetes.
Nat Immunol. (In press)

40. Brennan R.M., Petersen J., Neller M.A., Miles J.J., Burrows J., McCluskey J.,
Khanna, R., Rossjohn J. and Burrows S.R. 2011. The Impact of a Large and Frequent
Deletion in the Human T cell Receptor β Locus on Antigen-specific Immunity. J.
Immunol. (In press)

* Indicates co-shared authorships