Dokumen Artikel Penelitian ini milik penulis/penelliti yang diserahkan sebagian (judul dan Abstrak) hak ciptanya kepada

Universitas Airlangga untuk digunakan referensi dalam penulisan artikel ilmiah. Penulis : MIA RATWITA ANDARSINI Fakultas : Kedokteran FADIL RULIAN, MARIA CHRISTINA SHANTY LARASATI, BAMBANG PERMONO ,

Tim Peneliti : I Dewa Gede Ugrasena, dr., SpA(K).,

HIV INFECTION IN HB E THALASSEMIA CHILD

Abstrak : <!-- /* Font Definitions */ @font-face {font-family:"Cambria Math"; panose-1:2 4 5 3 5 4 6 3 2 4; mso-font-charset:1; mso-generic-font-family:roman; mso-font-format:other; mso-font-pitch:variable; mso-font-signature:0 0 0 0 0 0;} @font-face {font-family:Calibri; panose-1:2 15 5 2 2 2 4 3 2 4; mso-font-charset:0; mso-generic-font-family:swiss; mso-font-pitch:variable; mso-font-signature:-520092929 1073786111 9 0 415 0;} /* Style Definitions */ p.MsoNormal, li.MsoNormal, div.MsoNormal {mso-style-unhide:no; mso-style-qformat:yes; mso-style-parent:""; margin-top:0in; margin-right:0in; margin-bottom:10.0pt; margin-left:0in; line-height:115%; mso-pagination:widow-orphan; font-size:11.0pt; font-family:"Calibri","sans-serif"; mso-ascii-font-family:Calibri; mso-ascii-theme-font:minor-latin; mso-fareast-font-family:Calibri; mso-fareast-theme-font:minor-latin; mso-hansi-font-family:Calibri; mso-hansi-theme-font:minor-latin; mso-bidi-font-family:"Times New Roman"; mso-bidi-theme-font:minor-bidi;} .MsoChpDefault {mso-style-type:export-only; mso-default-props:yes; mso-ascii-font-family:Calibri; mso-ascii-theme-font:minor-latin; mso-fareast-font-family:Calibri; mso-fareast-theme-font:minor-latin; mso-hansi-font-family:Calibri; mso-hansi-theme-font:minor-latin; mso-bidi-font-family:"Times New Roman"; mso-bidi-theme-font:minor-bidi;} .MsoPapDefault {mso-style-type:export-only; margin-bottom:10.0pt; line-height:115%;} @page Section1 {size:8.5in 11.0in; margin:1.0in 1.0in 1.0in 1.0in; mso-header-margin:.5in; mso-footer-margin:.5in; mso-paper-source:0;} div.Section1 {page:Section1;} --> Background:Children with thalassemia major survive mainly on regular blood transfusions, which may expose them to different transfusion-transmitted infections (TTIs), especially hepatitis B, hepatitis C, HIV, and Treponema pallidum. The risk of HIV transmission is estimated to be 1:1.930.000, although it is difficult to be precise with such a low incidence. Objective:To report a case of HIV infection in a child with Hb E Thalassemia Case Report:R, 14 year-old girl with Hb E Thalassemia, has received regular blood transfusion in Tulungagung and Surabaya hospital since she was 3 years old. She was planned to undergo splenectomy because of the massive enlargement of spleen which causes concern about possible splenic rupture. Preoperation laboratory examination for HIV infection using ELISA method was positive but CD4 absolut was normal and Hbs Ag or anti HCV were negative. The ELISA method for HIV infection examination for her parents was negative. There were no history of drug abuse, sexual intercourse, reuse of contaminated needles and syringe, and tattoing/traditional piercing. The antiviral drug has not been given because CD4 absolute level was more than 500 cell/uL and the patient was in a good condition. Conclusion:A case of HIV infection in a child with HbE Thalassemia, we assumed HIV infection was acquired through regular transfusion.

Keywords : thalassemia, blood transfusion, HIV infection Keyword : thalassemia, blood transfusion, HIV infection

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