Medical University - Sofia, Medical Faculty Department of Internal Medicine Synopsis of state examination On internal medicine for medical

students

I.Pulmonary Diseases 1.Acute bronchitis, tracheobronchitis, broncheolitis 2. Chronic bronchitis, pulmonary emphysema chronic obstructive pulmonary disease. 3.Respiratory failure pathophysiology, and clinical features 4. Bacteraial community acquired pneumonia 5. Nonbacterial community acquired pneumonia 6. Hospital acquired pneumonia and pneumonia in immunocompromised patients. 7. Bronchiaectasis. Pulmonary abscess 8.Pleural effusions 9.Pulmonary Tuberculosis 10. Pulmonary embolism 11.Astma

II. Cardiovascular diseases 1.Diseases of the mitral valve:mitral stenosis 2. Diseases of the mitral valve: mitral regurgitation 3. Diseases of the aortic valve: aortic stenosis 4.Diseases of the aortic valve: aortic insufficiency 5.Endocarditis 6.Pericardial diseases, classification.Pericardiac tamponade. 7.Pericarditis. 8.Myocardial diseases: myocarditis 9.Myocardial diseases: cardiomyopathies 10.Acute heart failure: cardiac asthma, pulmonary edema, cardiogenic shock etiology, haemodynamics, clinical features. 11. Treatment of the acute heart failure.

12.Chronic congestive heart failure etiology, pathogenesis, clinical features. 13. Cardiac function parameters in Chronic congestive heart failure(CCHF). Treatment of CCHF. 14. Ischemic heart disease:classification. Stable Angina pectorisclinical features , treatment. 15.Acute coronary artery syndromes: Acute myocardial infarction with -ST segment elevation. 16. Acute coronary artery syndromes without ST segment elevation: unstable angina pectoris, myocardial infarction without -ST segment elevation. 17.Treatment of conductive disturbances 18.Rhythm abnormalities: supraventricular arrhytmias, classification, haemodynamic, clinical features. 19.Treatment of supraventricular arrhytmias. 20. Rhythm abnormalities: ventricular arrhytmias, classification, haemodinamic, clinical features.. 21 Ventricular arrhytmias, treatment 22. Antiarrhytmic drugs: classification, dosage. 23. Hypertension: etiology, classification, clinical features complications. 24.Hypertension: treatment 25.Acute Rheumatic feaver. Rheumocarditis. 26. Chronic Cor pulmonale 27.Aortic diseases: aortic dissection, aortic aneurysm, Takayashu disease; III. Rheumatic diseases. 1.Rheumatoid arthritis 2. Ankylosing spondilitis (Bechterevs disease) 3.Reactive arthritis 4.Reiters disease 5.Rheumatic feaver 6.Psoriatic arthritis 7.Systemic lupus erythematosus(SLE). 8.Systemic sclerosis 9.Polymyosistis(PM), dermatomyosistis(DM). 10.Vasculitis clinical features and classification. 11.Henoch Schonlein purpura

12.Ostheoarthrosis 13.Gout 14.Ostheporosis 15.Soft tissue rheumatism classification. IV. Hematologic diseases 1.Iron deficiency anemia 2.Macrocytic and megaloblastic anemias 3. Haemolitic anemias. Hemolysis. 4.Aplastic anemia.Agranulocytosis. 5. Hodjkins disease 6. Non-Hodjkins lymphomas 7.Chronic lymphocytic leukemia 8.Myeloma multiplex 9.Chronic myelogenous leukemia 10.Polycytemia vera 11.Acute myeloid leukemia. 12.Acute lymphocytic leukemia(ALL) in adults. 13.Hemorrhagic diathesis - classification. Thrombocytopenia classification. Autoimmune thrombocytopenia. 14.Hemorrhagic diathesis classification. Haemophyllia. 15. Treatment with cytostatics and immunosuppressive drugs. 16.Thrombembolism. Anticoagulant treatment. V.Endocrine and metabolic diseases 1.Diabetes mellitus etiopathogenesis, clinical features. 2.Diabetes mellitus - treatment. 3. Diabetes mellitus -complications. 4.Obesity and Metabolic syndrome. 5. Dislipidemia 6.Hypothyreoidismus 7.Thyreotoxicosis. Hyperthyreoidismus. 8. Nodular goiter. Endemic and sporadic goiter. 9.Hyperproalctinemia. Prolactinom 10.Hypercalciemic states 11.Hypocalciemic states 12..Acromegalia and insipid diabetes. 13..Hypercorticism 14.Hypocorticism 15. Hypogonadism in male and female. Clinical feature.

16.Autoimmune disorders of thyreoid gland. 17. Polycystic ovary syndrome VI.Gastrointestinal diseases 1.Gastro-esophageal reflux disease (GERD) 2.Helicobacter pylori infection 3.Peptic ulcer 4.Malabsoption 5.Ulcerative colitis and Crohns disease 6.Other intestinal diseases 7.. Chronic viral hepatitis 8..Fatty liver. Alcoholic and nonalcoholic steatohepatitis 9..Primery billiary cirrhosis (PBC), primary sclerosing cholangitis 10.Autoimmune hepatitis 11.Liver cirrhosis etiology, pathogenesis, clinical features 12.Liver cirrhosis complications:esophageal varices, ascites, spontaneous bacterial peritonitis(SBP), hepato-renal syndrome, portal encephalopathy.(PE). 13.Ascites diagnosis, differential diagnosis, treatment 14.Cholelithiasis- etiology, pathogenesis, clinical features. 15. Cholelithiasis complications: cholecystitis, cholangitis. 16. Acute and chronic pancreatitis 17. Cholestasis /jaundice syndrome. VII. Renal Diseases 1.Acute postreptococcal glomerulonephritis(GN) 2.Idiopathic nephrotic syndrome 3.Membranous glomerulonephritis 4.IgA glomerulonephritis(Bergers disease). 5.Membranoprolipherative glomerulonephritis (MPGN) 6.Lupus nephritis 7.Kidney and diabetes. Renal amyloidosis 8.Acute urinary tract infections 9.Chronic pyelonephritis 10.Renal tuberculosis 11.Nephrolithiasis 12.Adult Polycystic Renal disease 13. Acute renal failure prerenal and renal parenchymal. 14.Chronic renal failure stages and clinical course.

VIII.Toxicology and allergic disorders. 1.Insect sting alergy 2.Anaphylaxis 3.Asthma 4.Allergy due to medications. 5.Serum disease 6.Methanol poisoning. 7. Poisoning with Nitrogen and its compounds. 8 Posoning with Chlorine and its compounds . 9.Carbon monoxide poisoning. 10. Mushrooms poisoning.. IX. Oncologic diseases I. Renal tumors II. Lung cancers. 3..Esopahgeal cancer 4 Gastric cancer 5.Tumors of the colon 6.Liver tumors 7.Pancreatic cancer 8.Carcinoma of the biliary ducts. 9.Tumor of the thyreoid gland X. Principals of treatment 1.Treatment of peptic diseases of the gastrointestinal tract. 2.Treatment of Helicobacter pylori infection. 3.Principles in treatment of chronic liver disease. 4.Treatment of chronic viral hepatitis. 5.Treatment of the liver cirrhosis complications: esophageal varices, ascites, spontaneous bacterial peritonitis, hepato-renal syndrome, encephalopathy. 6. Treatment of chronic cholestasis. 7.Antibacterial treatment of the billiary tract infection. 8,Treatment principles in poisoning. 9.Treatment of urinary tract infection 10.Treatment in glomerulonephritis 11..Diabetes mellitus - treatment with insulin and oral medications 12. Treatment of diabetic complications. 13. Treatment with NSADS

14.Treatment in predialysis period of chronic renal failure and indications for dialysis. 15,Clinical and pharmacological approach in pain control medication therapy. 16. Treatment of bacterial infection. 17. Treatment with diuretics 18. Treatment with steroids. 19.Treatment with immunomodulators 20.Treatment with cytostatics. 21. Treatment of the thrombembolism. 22. Treatment of pneumonia 23. Treatment of asthma. VAS