Drug Information

INTRODUCTION Physicians must be up-to-date with relevant drug-related literature in order to provide the most current drug information. The drug information may include information on essential drug list, pharmacology profile of the drug, indication, recommended dosage and some drug administrations, contraindication, side effect, possible drug interaction, adverse drug reaction and including how to report the adverse-drug-reaction The physicians must have advanced literature search and assessment skills to searching the information related to medicines. Today, the internet provides a plethora of drug information for both health care professionals and their patients. Many practitioners probably use the internet when seeking answers to questions. However, there is no quality control for these types of information sources on the internet, and practitioners may be jeopardizing their own credibility when using these resources. Therefore, with so many websites retrieving information from drug information references, the medical students should know which information should be able to use to support their knowledge on drug information. PRACTICAL WORK a. The aim of the practical work 1) To develop skill in identification and retrieval of drug information 2) To developing drug monographs 3) To develop skill in making report the adverse drug event b. Instruments and data 1) Personal computer and internet 2) Documents of drug information a) Indonesian essential drug list

b) Hospitals drug formulary 3) Internet website of drug information a) Drug and supplements information : http://www.nlm.nih.gov/medlineplus/ b) Drug interaction : http://www.drugs.com/ c) MIMS : http://www.mims.com/ d) WHO Anatomical Therapeutical Chemical (ATC) Code & Defined Daily Dose (DDD) : http://www.whocc.no/atcddd/ e) Medical subjects heading : http://www.nlm.nih.gov/mesh/MBrowser.html f) WHO essential drug list : http://www.who.int/medicines/publications/essentialmedicines/en/ 4) Form of reporting of the adverse drug event 5) Data on epidemiology of drug use c. Procedure Using the some data of drug use, the students identify 1) Generic name of the drugs 2) Drug classes, indication, pharmacokinetic and pharmacodynamic profile of the drugs 3) Recommended dosage and administration of the drugs 4) Potential side effect and contraindications of the drugs 5) Potential drug-drug interaction and its potential effect etc Fill the monograph

MONOGRAPH OF DRUG INFORMATION Generic Name: ATC Code: Trade Name: Manufacturer: Similar Drugs: Indications: Clinical Pharmacology: Pharmacokinetics: Parameters Peak Trough Distribution (Vd) Protein Binding T1/2 Metabolism Excretion

Renal: Hepatic: Renal: Feces:

Therapeutic Efficacy (clinical trials): Adverse Effects: Drug Interactions: Contraindications, Warnings, and Precautions: Monitoring: FEMA (Failure Modes & Effects Analysis) Pregnancy Category Overdose/Toxicity Specific Monitoring Availability and dosing Cost evaluation Drug

Usual Dosage

Cost/Month (Rp)

Summary and recommendation Monograph prepared by: References: