CURRICULUM VITAE A neuroradiologist by training, I specialized in Magnetic Resonance Imaging (MRI).

Introducing the technique in India in 1987 after coming back from the USA where I underwent a fellowship programme at the Beth Israel Hospital, New York. I was instrumental in setting up the First MR centers in various cities in India such as Bombay, Ahmedabad etc. and in abroad such as Sultanate of Oman and continued consulting for numerous other centres all over India and abroad. The result was a spurt in use of this technology at over 500 centers now operating in India & the Middle East. I was the Chief Consultant at the First MR Centre in India at Breach Candy Hospital and at Al Afaq in Oman for more than 15 years. I also started the First Lithotripsy centre in Gujarat in the year 1989. Recently started G. T. Hospital Imaging Centre (MRI & CT Scan) a first PublicPrivate-Partnership with Government of Maharashtra. The enterpreunial urge facilitated me to start a unique preventive & diagnostic clinic called Spectrum Healthcare in Bombay which is also a pioneer and leader in its field. I am the Medical Director of Spectrum Clinical Research (SCR), as a one-of-its-kind patient focused Clinical Research Organization (CRO), providing a wide spectrum of clinical research services viz. Pre Study, Study Management and Post Study Services for Phase I, II, III and IV Global Trials with a strong presence in India. I am also the Chairman of Medsphere Technologies Pvt. Ltd., which is a global teleradiology and PACS solution provider which develops teleradiology and PACS products and services for customers around the world. I am also the Director of Exemplar Lifecare Pvt. Ltd., a healthcare marketing company, which started a web-portal CHEENYKUM, for diabetes care in India using a proprietary mobile & web-based technology.

My detailed curriculum vitae is attached. VIRAL CHITTARANJAN SHAH Address : 2601 A, Vikas Towers 105/106 Walkeshwar Road, Malabar Hill, Bombay 400 006 Hospital : +91 22 23667850 Clinic : +91 22 22846357 Office : +91-22-40645100 / 66155565 Residence : +91 22 23640284 Mobile : +9198670-42277 Email : vshah@spectrumcr.com / vshah@spectrumhealthcare.co.in

EDUCATIONAL:

Bachelor of Medicine & Bachelor of Surgery (M.B.B.S.) from Lokmanya Tilak Medical College University of Bombay Passed November 1978 - 1st attempt. Diploma in Medical Radiological Diagnosis (D.M.R.D.) from Lokmanya Tilak Medical College University of Bombay Passed November 1980 - 1st attempt. Diploma in Medical Radiology & Electrology (D.M.R.E.) from College of Physicians & Surgeons Passed November 1980 - 1st attempt. Doctor of Medicine (M.D.) in Radio Diagnosis & Therapy from Lokmanya Tilak Medical College University of Bombay Passed November 1981 - stood 3rd in University. Fellowship in Computerized Axial Tomography - Ultrasound Neuro-radiology at Beth Israel Medical Centre, Mount Sinai University 10, Nathan D. Perlman Plaza, New York, N.Y. 100002, U.S.A.. Maharashtra Medical Council - Registration No. 41090 PROFESSIONAL EXPERIENCE: MEDICAL DIRECTOR 2004 to present SPECTRUM CLINICAL RESEARCH PVT. LTD. 401, Kshamalaya, 37 New Marine Lines Mumbai 400 020 MEDICAL DIRECTOR 1995 to present SPECTRUM HEALTHCARE 81-84, Lady Ratan Tata Medical & Research Centre M. Karve Road, Cooperage Mumbai 400 021 CHAIRMAN 2007 to present MEDSPHERE TECHNOLOGIES PVT. LTD. GF, B-18, 2nd Main, KEB Layout BTM 1st Stage, Bangalore - 560 076, Karnataka DIRECTOR 2009 to present EXEMPLAR LIFECARE PVT. LTD. (CHEENYKUM.COM) 401, Kshamalaya, 37 New Marine Lines Mumbai - 400020
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CHIEF CONSULTANT 2010 to present G.T. HOSPITAL IMAGING CENTRE Lokmanya Tilak Marg, Mumbai - 400001 CONSULTANT IN-CHARGE for the Magnetic Resonance Imaging (MRI) facilities 1988 to 2008. BREACH CANDY HOSPITAL AND RESEARCH CENTRE 60, Bhulabhai Desai Road Bombay-400 026. CONSULTANT IN-CHARGE for the Magnetic Resonance Imaging (MRI) and Extracorporeal Shockwave Lithotripsy (ESWL) facilities - 1988 to 1998
THE GUJARAT CANCER & RESEARCH INSTITUTE

Gujarat Cancer Society Civil Hospital Complex, Asarwa Ahmedabad-380 01 BETH ISRAEL MEDICAL CENTRE Mount Sinai University 10, Nathan D. Perlman Plaza New York, N.Y. 100002, U.S.A. a. b. c. d. Fellowship Observer in C.A.T. Scanning (Head & Body) from March 1, 1983 to September 30, 1983. Fellowship in C.A.T. scanning - Ultrasound (Neuroradiology) from July 1, 1983 to June 30, 1984. NMR Experience at Long Island NMR from July 1, 1984 to December 1, 1984. Evaluator at Fonar Corporation, Melville, New York for Federal Drug Administration.

LOKMANYA TILAK MEDICAL COLLEGE AND HOSPITAL Department of Radiology Sion, Bombay-400 022 a. b. c. House Officer from April 1, 1979 to February 20, 1980. Registrar from March 1, 1980 to August 31, 1981. Tutor from September 1, 1981 to December 31, 1981.

CLINICAL TRIAL EXPERIENCE: Conducted Clinical Trial as a Evaluator for Medical Device at Fonar Corporation, Melville, New York for submission to US-FDA. Conducted Clinical Trial for Contrast Media Trials in MR/CT. Conducted a Multi-Centre, Double-Blinded, Randomized, Placebo-Controlled, Parallel Group, Flexible Dose Titration, Add-On of Study Drug in the Treatment of study drug for Major Depressive Disorder. Conducted a Multi-Centre, Standard of Care-Controlled Study to Evaluate the Long-Term
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Safety of the study drug for the Treatment of Chronic Low Back Pain. Conducted a Randomized, Double-Blind, Placebo Control, Parallel Assignment, Safety/Efficacy of Study drug for treatment of Acute Schizophrenia. Conducted a Comparison Study to detect Respiratory Infectious Disease by Smear, Culture, and Nucleic Acid Amplification by Specimen Processing. ONGOING CLINICAL TRIALS: 1. 2. 3. Managing a Pilot Study to evaluate the validity and cultural equivalence of three psychometric scales in subjects with mild to moderate Alzheimers Disease and Vascular Dementia. Managing a Multi-Centric, Phase III, Double-Blind, Randomized, Parallel Group, PlaceboControlled Study of Intravenous Study Drug in the Treatment of Post Operative Ileus. Managing a 54 week, Double-Blind, Randomized, Placebo-Controlled, Parallel Group, Study to Investigate the Effects of Study drug as adjunctive therapy to ACE-Inhibitors in subjects with Mild to Moderate Alzheimers Disease. 4. Managing a Multicenter, Phase III, Double-blind, Randomized Study to Compare the Safety and Efficacy of the study drug versus placebo in the treatment of acute gastroenteritis in adult travelers. 5. 6. Managing a Multi-Centre, Randomized, Double-Blind, Placebo-Control, Study to evaluate efficacy and safety of the study drug on Sleep Maintenance Insomnia. Managing an international, multicenter, randomized, double-blind, double dummy, parallel group, study of 3-month or 6-month treatment with the study drug in the treatment of patients with symptomatic pulmonary embolism with or without symptomatic deep venous thrombosis. 7. Managing a Randomized, Phase III-b, Multi-centre, Open-label, Parallel study of the study drug given concomitantly with chemotherapy vs chemotherapy alone in patients with inoperable gastric and gastro-oesophageal cancer" study. 8. Managing a Randomized, Double-Blind, Placebo And Active Comparator-Controlled, ParallelGroup Study Of The Efficacy And Safety Of the study drug As Monotherapy Treatment Of Type 2 Diabetes Mellitus. 9. Managing a Double-Masked, Randomized Study of the Safety and Effectiveness of the study drug as an Agent for Selective Staining of the Anterior Capsule during Cataract Surgery. 10. Managing a multicenter, randomized, double-blind, parallel, placebo-controlled clinical study
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will assess the efficacy and safety of the study drug in adult and pediatric burn patients with fevers greater than or equal to 100.4F (38.0C). 11. Open-Label, clinical trial to assess the efficacy of Saffola atta pre mix added to regular wheat flour along with dietary modification and exercise on LDL cholesterol of patients with Hyperlipidemia. 12. A multi-center, prospective, open-label, clinical trial to assess the safety and the efficacy of a new intravenous immune globulin (IGIV3I Grifols10%) in patients with idiopathic (immune) thrombocytopenic purpura. 13. Randomized, double-blind study comparing the immunogenicity of two different brands of human insulin for the treatment of diabetes. 14. A Multi-Center, Randomized, Open-Label, Parallel, Active-Comparator, Multiple Dose Trial to determine the Efficacy, Safety, and Pharmacokinetics of Intravenous Ibuprofen in Pediatric Patients. 15. A Multi-Center, Randomized, Open-Label, Parallel, Active-Comparator, Multiple Dose Trial to determine the Efficacy, Safety, and Pharmacokinetics of Intravenous Ibuprofen in Pediatric Patients. 16. Study for the Safety and Efficacy Evaluation of the Electro muscular Stimulation Device. 17. Randomized, parallel-group, open-label clinical study to assess the strong heart and fit body claim in the Hyperlipidemic subjects with oats, diet & exercise compared with diet and exercise alone. 18. Openlabel, Crossover, clinical study to assess the strong heart and fit body claim in unfit population (overweight and/ or with Pre-diabetes and/or mild to moderate hypertensive) prescribed with oats, diet & exercise comparative to the diet and exercise alone. 19. A randomized, single-blind, parallel group study to compare the IOP lowering effect of Forskolin 2% QAM v/s Xalatan 0.005% QHS and Forskolin 2% BID v/s Timolol 0.5% BID in patients with ocular hypertension or mild open angle glaucoma. 20. A single-center, randomized, controlled study to evaluate the safety and effectiveness of the electro muscular stimulation device to improve skin elasticity, firmness and to reduce the signs of facial Aging in healthy adults after 8 weeks of product use. 21. Efficacy of Therapie Vs Minoxidil in the treatment of Male Pattern Hair loss. 22. A prospective, controlled, randomized study to evaluate the glycemic index of 4 rice samples in healthy volunteers. 23. A randomized, comparative, reference controlled study to evaluate the glycemic index of 4 rice
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samples in type 2 diabetic subjects. 24. A single-center study to evaluate the safety and effectiveness of the electro muscular stimulation device to improve skin fairness and blood circulation of facial ageing in healthy adults after application of the product use.
THESIS:

"Carotid Angiography & Intracranial Tumors" written under guidance of Prof. O.J. Tavri, Bombay University - Accepted November 1981.
AWARDS:

1.

NMR Imaging in Malignancies of the Upper Aerodigestive Tract. Presentation and Scientific Exhibit at RSNA - 1983 (Honorable Mention). Imaging of the Larynx. Presented at the American Roentgen Ray Society Meeting, Las Vegas - 1984. Certificate of Merit for Scientific Exhibit. Comparative Study of Plain MRI & Gadolinium DTPA enhanced MRI in C.N.S. Presented at the XLIII Annual Congress of Radiology & Imaging organized Indian Radiological & Imaging Association at Hyderabad from January 4 to 7, 1990. Awarded the "Dr. Ashoke Mukherjee Memorial Award".

2.

3.

PAPERS AND PRESENTATIONS: 1. 2. Desmoid Tumor of the Neck (Case Report) American Journal of Neuroradiology - July/August, 1984. NMR Imaging of the Malignancies of Larynx and Tongue Base. Presented at the second Annual Scientific Meeting of the Society of Magnetic Resonance in Medicine. Participated in the XIV World Congress of Neurosurgery at New Delhi from October 22 to 27, 1989 and presented a paper on MRI of Cranio vertebral junction. Presented a paper on Future of MRI in India at the PMB-Industry-Agency Meeting held at the Bhabha Atomic Research Centre, Bombay on October 25, 1989. MRI - the Diagnostic Modality for Cerebello Pontine Tumors - Evaluation of 3000 MRI's. Presented at the XLIII Annual Congress of Radiology & Imaging organized by the Indian Radiological and Imaging Association at Hyderabad from January 4 to 7, 1990. Differentiation of Idiopathic and Obstructive Syringomyelia with MR. Presented at the XLIII Annual Congress of Radiology & Imaging organized by the Indian Radiological and Imaging Association at Hyderabad from January 4 to 7, 1990.
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3. 4. 5.

6.

7.

Evaluation of Cranio-Vertebral Junction by MRI Presented at the XLIII Annual Congress of Radiology & Imaging organized by the Indian Radiological and Imaging Association at Hyderabad from January 4 to 7, 1990. Evaluation of Spinal Cord Lesions with MRI. Presented at the XLIII Annual Congress of Radiology & Imaging organized by the Indian Radiological and Imaging Association at Hyderabad from January 4 to 7, 1990. Evaluation of Lumbar Disc Diseases with MRI. Presented at the XLIII Annual Congress of Radiology & Imaging organized by the Indian Radiological and Imaging Association at Hyderabad from January 4 to 7, 1990. MRI - Knee - A better alternative to Arthroscopy. Presented at the XLIII Annual Congress of Radiology & Imaging organized by the Indian Radiological and Imaging Association at Hyderabad from January 4 to 7, 1990. CNS Tuberculosis - MRI & CT Evaluation. Presented at the XLIII Annual Congress of Radiology & Imaging organized by the Indian Radiological and Imaging Association at Hyderabad from January 4 to 7, 1990. Neurocysticercosis - Cerebral & Spinal - Comparison of CT Scanning & MRI - A study of 35 Cases. Presented at the XLIII Annual Congress of Radiology & Imaging organized by the Indian Radiological and Imaging Association at Hyderabad from January 4 to 7, 1990. MRI of Multiple Sclerosis - Indian Experience. Presented at the XLIII Annual Congress of Radiology & Imaging organized by the Indian Radiological and Imaging Association at Hyderabad from January 4 to 7, 1990. Craniopharyngioma in Children Presented at the Conference of Indian Society of Paediatric Neurosurgery held at Bombay Hospital on July 21, 1990. Presented a paper on "MRI more specific than CT in cranial Tuberculosis" at XIV International Neuroradiology Conference held at London, U.K. in August 1990. Published in the journal - "Neuroradiology" - Volume 331 - March 1991. Presented a paper on "Spinal Arachnoiditis - MR appearances and evaluation" at XIV International Neuroradiology Conference held at London, U.K. in August 1990. Published in the journal - "Neuroradiology" - Volume 331 March 1991. Presented a paper on "Cranial Neurocysticercosis - MRI V/S CT - study of 35 cases" at XIV International Neuroradiology Conference held at London, U.K. in August 1990. Published the journal - "Neuroradiology" - Volume 331 March 1991 Presented a paper on "MRI in Multiple Sclerosis - Indian Experience" at XIV International Neuroradiology Conference held at London, U.K. in August 1990 . Published in the journal "Neuroradiology"- March 1991
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8.

9.

10.

11.

12.

13.

14.

15.

16.

17.

18.

19.

Comparative Study of Plain MRI & Gadolinium DTPA enhanced MRI in Craniospinal Lesions - An Analysis of 7500 cases. Presented at the Annual Conference of Neurological Society of India, December 1990 at Indore. Spinal Localization using Vitamin 'E' Capsules - Presented at the 44th National Congress of Indian Radiological & Imaging Association held at Pune in January, 1991 MR Imaging of Orbits - Presented at the 44th National Congress of Indian Radiological & Imaging Association held at Pune in January, 1991 Mediastinal MR Imaging - Presented at the 44th National Congress of Indian Radiological & Imaging Association held at Pune in January, 1991 MR of Congenital Cranio-Cerebral Anomalies - Presented at the 44th National Congress of Indian Radiological & Imaging Association held at Pune in January, 1991 MR Imaging of Tuberculous Spondylitis - Presented at the 10th Annual Meeting of the Society Magnetic Resonance Imaging held at Chicago, USA - April, 1991. Extradural and Intramedullary Tuberculous Granulomas - MR Specificity and Signal Characteristics - Evaluation of 30 patients - Presented at the XVIth World Congress of European Society of Neuroradiology at Zurich, October, 1991. Correlation of MR Cord Signal Intensity in Tuberculous Spondylitis to Patient Prognosis Its Impact on Decision of Surgical Intervention and Approach - study of 40 cases Presented at the XVIth World Congress of European Society of Neuroradiology at Zurich, October, 1991. MRI in Cerebral Malaria - Analysis of 11 Cases - Poster at the XVIth World Congress of European Society of Neuroradiology at Zurich, October, 1991. Tuberculous Osteitis without Discitis - MR Evaluation - Presented at the XVIth World Congress of European Society of Neuroradiology at Zurich, October, 1991. Giant Cerebral Tuberculomas - CT v/s MR - Analysis of 21 Cases - Presented at the XVIth World Congress of European Society of Neuroradiology at Zurich, October, 1991. Magnetic Resonance Imaging of Suprasellar lesions with special reference of Craniopharyngioma - Published in Neurology India, Volume 39, 1991 MR in Lesions of the Spinal Cord - Presented at the Neurological Society of India at Madras on December 19, 1993. MR Imaging of Infratentorial Tumors in Children - Presented at Indian Society for Paediatric Neurosurgery at Madras on 20th December 1993. Conference: Poster Presentation - Aneurysmal Bone Cysts of Axial Skeleton; Findings with Magnetic Resonance Imaging. Annual Congress of American Roentgen Ray Society, New Orleans, LA. April 25-30, 1994.
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20. 21. 22. 23. 24. 25.

26.

27. 28. 29. 30. 31. 32. 33.

34. 35.

Cost Effectiveness of MR in Specific Situations In India - Oxford, England, August 2-6, 1995. Written a chapter on MRCP in the book Looking into learning thing through magnetic resonance imaging by Prof. Ramesh Choughule, 2005

MEMBERSHIP: Association of Clinical Research Professionals (ACRP) Drug Information Association (DIA). Radiological Society of North America (RSNA). European Society of Neuroradiology. Society of Magnetic Resonance. Indian Radiological & Imaging Association (IRIA). Indian Society of Magnetic Resonance Imaging. US-India Business Council. The Indo-US Entrepreuners (TiE). Federation of Indian Chamber of Commerce and Industry (FICCI) Biotech Consortium India Limited (BCIL) European Business Group (EBG)

CONTINUING EDUCATION: 1. 2. 3. 4. 5. 6. 7. 8. 9. 10. Attended Beth Israel Medical Centre for Ultrasound from January 1986 to March 1986. Attended NMR at Long Island NMR, Hillside, New York from April 1986 to July 1986. Participated in the 13th International Symposium - Neuroradiological - held at Stockholm, Sweden from July 21, 1986 to July 26, 1987. Visited various Magnetic Resonance site in Germany in August/October 1986. Attended the RSNA conference in Chicago, U.S.A. - 1986,1987 and 1988. Conducted CME on "Imaging In Orthopaedics" for the Maharashtra Orthopaedic Association at Breach Candy Hospital & Research Centre, on December 14, 1989. Conducted CME on MRI for Regional Conference of Gujarat State Branch of Indian Radiological & Imaging Association at Ahmedabad - February, 90. Attended International Workshop on Contrast Media in MRI at Berlin, West Germany from February 1 to 3, 1990. Attended XIV Symposium Neuroradiologicum from June 17 to 23, 1990 at London. a). Magnetic Resonance Imaging of Brain and Spinal Cord. b). Magnetic Resonance Imaging in Body Imaging
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Presented at the Frontiers in Medical Imaging seminar organized by the Indian Radiological & Imaging Association's Kerala state branch on July 15, 1990. 11. Course Co-ordinator - "Imaging Update - 90" Organized by Maharashtra State Branch of Indian Radiology & Imaging Association, held at Bombay from October 31 to November 4, 1990 Editor-in-Chief of MRI-Newsletter - a publication of Breach Candy Hospital and Research Centre. Organised and attended Course on Good Clinical Practices in February 2006 in accordance with Association of Clinical Research Professionals (ACRP) guidelines. Organised a Raters Training Programme for MMSE, ADCS-ADL and ADAS-COG Scales certified by i3 Research.

12. 13. 14.

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