This audio program discusses severe mood dysregulation and bipolar disorder in children; a longitudinal study of cortical development in children with varying degrees of hyperactivity; whether gray matter volume in adults being treated for alcohol dependence is related to the time until relapse; a schizophrenia study comparing mortality rates for ziprasidone and olanzapine; use of technology to obtain real-time assessments of symptoms and substance use in schizophrenia patients. Articles can be viewed online at www.ajp.psychiatryonline.org.