This podcast was developed by Lucy Duan, Stephanie Erdle and Dr. Vy Kim for PedsCases.com. After listening to this podcast, the listener should be able to: differentiate allergic drug reactions from other adverse drug reactions, develop an approach to drug allergy diagnosis, understand the four main categories of drug allergies and their clinical manifestations, develop a differential diagnosis of other conditions to consider, and understand a general treatment approach to drug allergies.