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Chronic illnesses
Asthma
Chronic inflammatory disorder of the lungs
Cause is multiple
Subject to acute flare-ups Genetic predisposition Environmental exposures Viral infections
Classification of Asthma
Stepwise approach to managing asthma Based on
Frequency of symptoms Frequency/severity of exacerbations Lung function
P. 881-882 in text
Patho
Inflammation leads to airway hyperresponsiveness which results in physiologic manifestations
Respiratory Tree
Triggers
Stimulus which initiates the asthmatic episode
More patho
Antigen deposited on respiratory mucosa Lysozymes digest outer coating Foreign protein is released Immune sequence initiated IgE Release of chemical mediators Increased permeability of blood vessels
Contraction of smooth muscle Stimulation of mucus secretions Mucosal edema Airway remodeling leads to decreased lung function
Prolonged expiratory phase with wheezing, restlessness, anxiety Tripod position Speaks in short, panting phrases Secretions increase and cough becomes rattling
Drug therapy
SABA quick relief ICS Long-term control must be used with ICS
Anti-inflammatory
Cromolyn, ICS, leukotriene modifiers
LABA associated with increased death in adults so Salmeterol (serevent) and Formoterol are no longer approved in children (Only approved for COPD). Advair & Symbicort are still OK
Hydration
IV fluids ?NPO
Plan
teaching
Xolair
Monoclonal antibody (Omalizumab) Reserved for refractory asthma, must be over 12 years old. Lowers free IgE so only helpful if allergy is the trigger.(Check Serum IgE first). Expensive; risk of anaphylaxis (given subcu)
Murine monoclonal AB
Home management
Peak flow meter or symptom monitoring
Determine need for intervention Confirms effectiveness of tx
Allergen control
GREEN
80-100% of best Signals all is clear. Asthma is under good control No symptoms are present and routine treatment plan for maintaining control can be followed
Yellow
50-79% of best Signals caution Asthma is not well controlled. An acute exacerbation may be present. Maintenance therapy may need to be increased. Call physician if the child stays in this zone Red
Red
Below 50% of best Signals medical alert. Severe airway narrowing may be occurring. A short-acting bronchodilator should be administered. Notify physician if level does not return immediately and stay in the yellow or green zone.
Nursing Diagnoses
Ineffective airway clearance related to bronchoconstriction and edema AEB cough or wheeze. Impaired gas exchange related to airway obstruction and CO2 retention. Risk for Deficient Fluid Volume related to difficulty in drinking.
Anxiety/Fear (child and parental) r/t difficulty breathing and change in health status. Ineffective therapeutic regimen management (family) r/t lack of understanding about and need for daily mgt of a chronic disease.
Hygiene Hypothesis
There is a school of thought that in the USA we fail to challenge the newborns immune system with normal bacteria (Obsession with sterilizing, etc). Third world countries have almost no asthma Farm and rural environments have minimal asthma
Exposure to farm animals (even dogs) to a newborn seem to lessen the chance of asthma Soare we too clean?
Cystic Fibrosis
Chronic, genetic disorder affecting the exocrine glands Autosomal recessive Located on chromosome 7 Sodium transport problems Median survival 38.6 years (4/2006)
Thick, sticky mucous
Genetics 1 in 29 caucasians
carry the gene (in USA)
Diagnosis of CF
Positive sweat test with
+ family history /or Clinical signs Not reliable in children < 3 weeks
DNA
Genetic carrier Prenatally siblings
Clinical manifestations of CF
Meconium ileus (7-10%), late meconium passage. Growth failure Frothy, foul-smelling stools (steatorrhea) Salty taste Recurrent respiratory symptoms
Later manifestations of CF
Clubbing barrel-shaped chest portal hypertension frequent respiratory infections cough
Management of CF
Facilitate airway clearance and gas exchange Prevent/treat infection
Antibiotics
Prophylactic Treatment Inhaled TOBI
nebs Exercise/CPT
Meds for CF
Nebs
Bronchodilators Pulmozyme (dornase alfa) Hypertonic saline, TOBI
Nursing Care
Supportive and encouraging
Meds Nutrition
High cal/high protein Supplemental feedings
Bronchopulmonary dysplasia
Chronic lung disease (CLD) Primarily ELBW and VLBW
Patho of BPD
Immature lung is injured and develops chronic inflammation
Mechanical ventilation Prenatal/postnatal infection Oxygen therapy Increased pulmonary blood flow
Prevention of BPD
Surfactant Prenatal steroids Lowest possible pressures Lowest possible O2 concentration Bubble CPAP
Intermittent bronchospasms and mucous plugging Barrel shaped chest FTT O2 dependence; chronic CO2 retention
Management of BPD
Maintain oxygenation Control interstitial fluid Adequate nutrition Avoid infection
Nutrition
Ensure adequate calories Oral-motor stimulation
Nursing Diagnoses
Alteration in respiratory function Alteration in nutrition Anxiety Fluid volume deficit Activity intolerance Knowledge deficit Alteration in thermoregulation
Alteration in Nutrition
Calculate calorie needs Provide adequate calories Accurate I and O Daily weight Measure to encourage intake
Fourteen year old John is admitted with LRI and CF. This is his 20th admission. What abnormal physical assessment findings would you expect to see? What orders would you expect? What are developmental issues at this age? How would you adapt your nursing interventions to an adolescent
A child with CF is receiving Tobramycin 75 mg IV q 8 h. Safe dose is 2.5-3.3 mg/kg/dose Patient weighs 50 lb Is this a safe dose?
A baby with CF weighs 20 lb 3 oz Calorie needs are 120 cal/kg/day How many ounces of 27 cal formula would the child need per day?
A 6 year old child is being admitted from the MDs office with asthma. When he gets to the floor, what will you do first? VS weight O2 sat oxygen start IV neb treatment
What do you think about these? What do you think his breath sounds are like? How is he acting? What other systems do you want to assess closely?
Which statement indicates that parents have understood teaching about prevention of asthma attacks?
We will replace the carpet in our childs bedroom with tile Were glad the dog can still sleep in our childs room Well be sure to use the fireplace to keep the house warm. Well keep the plants in our childs room dusted