Hardy-Weinberg law was discovered by physicist W. Weinberg and mathematician G.H. Hardy in 1908.

Both experts were from the UK (Noor, 1996). According to Campbell (2000), HardyWeinberg law states that allele frequencies in a set of genes and genotif a population remain constant over generations unless there who act as agents selainan sexual recombination. In other words, sexual shift alleles caused miosis and random fertilization would not affect the genetic structure of a population (Prasetyo, Agus and Supratman, 2011).

Hardy-Weinberg law serves as a parameter evolution in a population. If the gene frequencies in a population remain constant from generation to generation, the population did not undergo evolution. If any one condition is not met then the gene frequency change, which means the population has been and is undergoing evolution (Biology Media Center, 2011).
Hardy-Weinberg law formulation can be explained as follows:

p + q = 1, then p = 1 - q and q = 1 - p
or 2PQ + P2 + q2 = 1

Authority further added that the condition of validity HardyWeinberg principle: a. Each gene has the same viability and fertility b. Mating occurs at random c. No mutation or gene mutation frequencies, as large d.Tidak migration e.Jumlah individuals in a population are always great
There are two things to note with respect to the law of Hardy - Weinberg: 1. The number of dominant and recessive gene frequency (p + q) is 1 2. The proportion of the three kinds of genotypes (p2 + q2 + 2PQ) is 1

Example 1. In a population of students of the Faculty of Animal Husbandry, consisting of students from the inner city, while 51% of students from out of town (tt) 49%. Compute: a. How many students from the gene frequency in the city (T) and gene students from out of town (t) in the population? b. What is the ratio genotifnya?
a. Gen students from out of town = tt = 49% tt = 40% = 0.7 then t == T+t=1 T = 1 - 0.7 = 0.3 Gene frequency T = 0.3 = 30% Gene frequency t = 0.7 = 70% b. TT = (0.3) 2 = 0.09 = 9% Tt = 2TT = 2 x 0.3 x 0.7 = 0.42 = 42% Tt = (0.7) x 2 = 0.49 = 49% So the comparison of genotype TT: Tt: tt = 9:42:49

Gene frequency is squared allele frequencies responsible for the genotipnya. The frequency can be calculated from the gene frequencies of alleles or genes with dominant action complete, with only two of tigamacam genotype phenotype. Her method of calculating the square root method. To find the gene and genotype frequencies of a population, used Hardy-Weinberg Law. Gene frequency is the frequency of an allele at a particular locus. Is calculated using the formula:
The number of specific alleles (with a copy) in the population Gene frequency = _____________________________________ The total number of alleles in the population

The frequency of the gene with a pair of alleles To calculate the frequency of a gene consists of a pair of alleles (eg, A and a), use the formula:
(2 X number of individuals AA) + (number of individuals Aa) p = f (A) = ___________________________________ (2 X total number of individuals)
(2 X number of individuals aa) + (number of individuals Aa) q = f (a) = ____________________________________ (2 X total number of individuals)

 For

example, we calculate the gene frequency of three alleles A, B and C. The number of each genotype were: AA = 10, AB = 35, B = 75, AC = 30, BC = 35, CC = 35 The total number is 220 The frequency of each allele are: f (A) = p = (2 x 10) + 35 + 30 = 0.193 (2 x 220) f (B) = q = (2 x 75) + 35 + 35 = 0.5 (2 x 220) f (B) = r = (2 x 35) + 30 + 35 = 0.306 (2 x 220)