Escolar Documentos
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MAGNÉTICA
TRANSCRANEAL
stucchi@amauta.rcp.net.pe
Noviembre 2009
Antecedentes
Efectos conductuales:
- Cambios en las estrategias de manejo del
estrés agudo.
- Disminución en el tiempo de inmovilidad
durante el estrés.
Efectos neuroendocrinos:
- Atenuación de la respuesta del eje
hipotálamo-hipofisiario-adrenocortical al
- estrés agudo.
Disminución en la síntesis de CRH y de
- vasopresina.
Aumento en los niveles de taurina, serina y
- aspartato.
Incremento en la liberación de dopamina en
- el hipocampo y en los núcleos accumbens y
estriado.
Incremento en los niveles de serotonina en el
hipocampo.
Franco López JA. Estimulación magnética transcraneal: su uso actual en neuropsiquiatría. MedUNAB 2004; 7:89-98.
EMT en la investigación
Lesiones cerebrales.
Hipertensión endocraneana.
Embarazo.
Niños.
Cohen H, et al. Repetitive transcranial magnetic stimulation of the right dorsolateral prefrontal
cortex in posttraumatic stress disorder: a double-blind, placebo-controlled study. Am J
Psychiatry 2004; 161(3): 515-24.
Daskalakis ZJ, et al. Repetitive transcranial magnetic stimulation for major depressive disorder:
a review. Can J Psychiatry 2008; 53(9): 555–566.
Epstein CM, et al. An open study of repetitive transcranial magnetic stimulation in treatment-
resistant depression with Parkinson's disease. Clin Neurophysiol 2007; 118(10): 2189-2194.
Fitzgerald PB, Daskalakis ZJ. A review of repetitive transcranial magnetic stimulation use in the
treatment of schizophrenia. Can J Psychiatry 2008; 53(9): 567–576.
Fitzgerald PB, et al. A randomized trial of anti-depressant effects of low and high frequency
transcranial magnetic stimulation in treatment resistant depression. Depression and Anxiety
2009; 26:229–234.
Franco López JA. Estimulación magnética transcraneal: su uso actual en neuropsiquiatría.
MedUNAB 2004; 7: 89-98.
George MS, et al. Transcranial magnetic stimulation: a neuropsychiatric tool for the 21st
century. J Neuropsychiatry Clin Neurosc 1996; 8(4): 373-382.
Hemond CC, Fregni F. Transcranial magnetic stimulation in neurology: What we have learned
from randomized controlled studies. International Neuromodulation Society 2007; 10(4): 333-
344.
Kaptsan A, et al. Right prefrontal TMS versus sham treatment of mania: a controlled study.
Bipolar Disord 2003; 5(1): 36-39.
Khedr EM, et al. One-year follow up of patients with chronic tinnitus treated with left
temporoparietal rTMS. Eur J Neurol 2009; 16(3): 404-408.
Kito S, et al. Regional cerebral blood flow changes after low-frequency transcranial magnetic
stimulation of the right dorsolateral prefrontal cortex in treatment-resistant depression.
Neuropsychobiology 2008; 58: 29–36.
Koppi S, et al. Repetitive transcranial magnetic stimulation in a patient with atypical Todd’s
postepileptic paralysis. Psychiatry Clin Neurosci 2008; 62(3): 368.
Lam RW, et al. Repetitive transcranial magnetic stimulation for treatment-resistant depression:
a systematic review and metaanalysis. Can J Psychiatry 2008; 53(9): 621–631.
Leung A, et al. rTMS for suppressing neuropathic pain: a meta-analysis. J Pain 2009 May 21.
[Epub ahead of print]
Loo CK, et al. A review of the safety of repetitive transcranial magnetic stimulation as a clinical
treatment for depression. Intl J Neuropsychopharmacology 2008; 11: 131–147.
Marcondes RA, et al. Repetitive transcranial magnetic stimulation improve tinnitus in normal
hearing patients: a double-blind controlled, clinical and neuroimaging outcome study. Eur J
Neurol 2009 Jul 9. [Epub ahead of print]
Maslenikov N, et al. Repetitive transcranial magnetic stimulation (rTMS) for the treatment of
depression in schizophrenia patients. Annals Genl Psychiatry 2008; 7(Suppl 1):S3-12.
McLoughlin D, Mogg A. Transcranial magnetic stimulation. In: Gelder MG, et al (ed). New
Oxford Textbook of Psychiatry. Second edition. Oxford University Press, 2009: 1263-1266.
O’Reardon JP, et al. Long-term maintenance therapy for major depressive disorder with rTMS.
J Clin Psychiatry 2005; 66(12): 1524-1528.
O’Reardon JP, et al. Efficacy and safety of transcranial magnetic stimulation in the acute
treatment of major depression: a multisite randomized controlled trial. Biol Psychiatry 2007;
62(11): 1208–1216.
Politi E, et al. Daily sessions of transcranial magnetic stimulation to the left prefrontal cortex
gradually reduce cocaine craving. Am J Addictions 2008; 17: 345-346.
Prasko J, et al. The effect of repetitive transcranial magnetic stimulation (rTMS) on symptoms
in obsessive compulsive disorder. A randomized, double blind, sham controlled study. Neuro
Endocrinol Lett 2006; 27(3): 327-332.
Sachdev PS, et al. Repetitive transcranial magnetic stimulation for the treatment of obsessive
compulsive disorder: a double-blind controlled investigation. Psychol Med 2007; 37(11): 1645-
1649.
Tranulis C, et al. Should we treat auditory hallucinations with repetitive transcranial magnetic
stimulation? A metaanalysis. Can J Psychiatry 2008; 53(9): 577–586.
Walsh V, Cowey A. Transcranial magnetic stimulation and cognitive neuroscience. Nat Rev
Neurosci 2000; 1: 73-79.