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Dr. I Gusti Ayu Widianti, M.Biomed



ANATOMY DEPARTMENT
UDAYANA UNIVERSITY
Scientist / ilmuwan:
Lifelong study Internet international
communication
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Bagian Anatomi FK UNUD
Leading causes of death
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Heart disease
Malignant neoplasms
Cerebrovascular diseases,
Chronic obstructive pulmonary disease
Pneumonia and influenza
Accidents
Diabetes mellitus
Suicide, nephritis, chronic liver disease, etc
etc



National Health Statistics, 1999
Major disorders
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The heart: Coronary artery disease
ischemic heart disease
myocardial infarction
The blood vessels: atherosclerosis
hypertension
varicose vein
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GENETIC PREDISPOSITION
EXCESSIVE CHOLESTEROL
SEDENTARY LIFE
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LARGE QUANTITIES OF CHOLESTEROL
DEPOSITED BENEATH THE ENDOTHELIUM AT
MANY POINTS IN ARTERIES
INVADED BY FIBROUS TISSUE AND
FREQUENTLY CALCIFIED
NET RESULT IS DEVELOPMENT OF
ATHEROSCLEROTIC PLAQUES
BLOCK OR PARTIALLY BLOCK BLOOD FLOW
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Weight reduction
Dietary sodium
Rich in vegetables & fruits
Physical activities
Stop smoking
Moderation alcohol
consumption
LIFE STYLE CHANGES

Circulatory System

1.Cardiovascular system

The heart (cor)
System of blood vessel

2. System of lymphatics
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The site of exchange
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Capillary Capillary
Cell
Arteriole Venule
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Stroke volume: 70 ml
5 liter/minute
7,200 liters/day
216,000 liters/month
2,628,000 liters/year

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Two major components:
The heart and system of blood vessels
Major functions:
Transport of oxygen and nutrients
Transport of CO
2
and waste products
Two major divisions
Major or systemic circulation
Lesser or pulmonary circulation

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Oxygenated blood
(O
2
& nutrients)
Deoxygenated blood
(CO
2
& waste products)
Systemic circulation
Pulmonary
circulation
Oxygenated blood

Deoxygenated blood
RV
LA
RA LV
RA=right atrium, LA=left atrium, RV=right ventricle, LV=left
ventricle
Lungs
Heart
Whole body
Heart

Veins Arteries
15mmHg
Venules
Arterioles 60 mmHg

Capillaries
35 mmHg




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Circulation
Venules=very small veins; arterioles=very small arteries
Aorta
120mmHg
Vena cava
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OVERVIEW OF THE CARDIOVASCULAR SYSTEM
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PULMONARY
CIRCULATION
SYSTEMIC
CIRCULATION
VALVE
VEIN
LYMPH NODE
LYMPH
CAPILLARIES
HEART
THORACICUS
DUCT
CAPILLARIES
ARTERIES
LYMPH NODE
LYMPH
CAPILLARIES
20 l / day
BLOOD
7200 l
/day
LYMPH
BLOOD
CAPILLARIES
3 l / day
17 l /day
The Heart

A four-chamber, powerful, muscular pump
Divided into two halves: left heart & right
heart.

Left heart: left atrium & left ventricle
Receives oxygenated blood (arterial
blood) from the lungs
Distributes it to the whole body.

Right heart: right atrium & right ventricle
Receives deoxygenated blood (venous
blood) from the whole body, sends it to the
lungs.

The walls of the left ventricle is the thickest.
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Boundaries:
left and right pleural cavities,
diaphragm,
anterior and posterior leaves of fibrous
pericardium, and
superior aspect of the left and right pulmonary
arteries

Contents:
Heart and pericardium
Roots of the great vessels
Arch of azygos vein
Main bronchi


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Double-walled fibroserous sac, encloses the
heart and the roots of its great vessels
Pericardial cavity:
The potential space between the opposing
layers of the parietal and visceral of serous
pericardium
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The wall consist of three layers:
Epicardium
Myocardium
Endocardium

The fibrous skeleton of the heart
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A special system for generating rhytmical
electrical impuls to cause rhytmical contraction
of the heart muscle and conducting these
impulses rapidly through the heart
Allow all portions of the ventricles to contract
simultaneously which essential for most
effective pressure generation in the ventricular
chamber
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A-V node (atrioventricular
node)
Conduction through the atrial wall
Sinoatrial node (sinus node)
A-V bundle (bundle of His)
Right & left branches
Purkinje fibers
PACE-MAKER
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A GROUP OF CELLS AS S-A NODE THAT SERVES
TO ESTABLISH AND MAINTAINING A
RHYTHMIC ACTIVITY
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Number of heart beats per minute
Classification of heart rate
Normal heart rate; 60 100/minute
Bradycardia: 60 beats per minute
Tachycardia: 100 beats per minute

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Two most common sites:
In the side of the neck: carotid pulse by
palpating the common carotid artery
At the wrist: radial pulse by palpating the
radial artery
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Normal and optimal: 120/80 (adults)

Abnormal high: Hypertension

Systolic Hypertension (wide pulse pressure)

Systolic and diastolic hypertension: Increased
peripheral vascular resistance
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THE FUNCTIONS OF LYMPHATICS
DRAINAGE OF TISSUE FLUID, COLLECTION OF
LYMPH PLASMA AND TRANSPORT OF LYMPH
TO THE VENOUS SYSTEM
ABSORPTION AND TRANSPORT OF FAT FROM
THE INTESTINE.
FORMATION OF A DEFENCE MECHANISM

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Right lymphatic duct (ductus lymphaticus
dexter):
The right halves of head, neck and thorax,
and the right upper limb
The thoracic duct (ductus lymphaticus
sinister):
The remainder of the body
Both duct eventually open into the
corresponding subclavian veins (venous
angles)
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Lymphatic plexuses (lymphatic capillary)
Lymphatics vessels
Lymph nodes
Lymphocytes
Lymphoid tissue
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Vascularization of head
and neck.

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