Copyright 2014 Wolters Kluwer Health | Lippincott Williams & Wilkins
Chapter 20: The
Muscular System Copyright 2014 Wolters Kluwer Health | Lippincott Williams & Wilkins Learning Objectives Compare the location and function of smooth, cardiac, and skeletal muscle. Describe the typical structure of a skeletal muscle. Briefly describe the mechanism of muscle contraction. Explain how muscles work together to produce movement. Describe the main types of movements produced by muscles. Copyright 2014 Wolters Kluwer Health | Lippincott Williams & Wilkins Learning Objectives (contd) List some of the criteria for naming muscles and give examples of each. Identify and use the roots pertaining to the muscular system. Describe at least seven disorders that affect muscles. Interpret abbreviations pertaining to muscles. Copyright 2014 Wolters Kluwer Health | Lippincott Williams & Wilkins Pretest 1. The neuromuscular junction is between a muscle and a: (a) gland (b) neuron (c) bone (d) gonad
Copyright 2014 Wolters Kluwer Health | Lippincott Williams & Wilkins Pretest 1. The neuromuscular junction is between a muscle and a : (a) gland (b) neuron (c) bone (d) gonad
Copyright 2014 Wolters Kluwer Health | Lippincott Williams & Wilkins Pretest 2. In the muscular system, the opposite of the origin is the: (a) counterorigin (b) agonist (c) diaphragm (d) insertion Copyright 2014 Wolters Kluwer Health | Lippincott Williams & Wilkins Pretest 2. In the muscular system, the opposite of the origin is the: (a) counterorigin (b) agonist (c) diaphragm (d) insertion Copyright 2014 Wolters Kluwer Health | Lippincott Williams & Wilkins Pretest 3. The quadriceps femoris muscle forms the anterior part of the: (a) neck (b) back (c) thigh (d) abdomen Copyright 2014 Wolters Kluwer Health | Lippincott Williams & Wilkins Pretest 3. The quadriceps femoris muscle forms the anterior part of the: (a) neck (b) back (c) thigh (d) abdomen Copyright 2014 Wolters Kluwer Health | Lippincott Williams & Wilkins Pretest 4. The opposite of flexion is: (a) rotation (b) antiflexion (c) relaxation (d) extension Copyright 2014 Wolters Kluwer Health | Lippincott Williams & Wilkins Pretest 4. The opposite of flexion is: (a) rotation (b) antiflexion (c) relaxation (d) extension Copyright 2014 Wolters Kluwer Health | Lippincott Williams & Wilkins Pretest 5. The opposite of abduction is: (a) adduction (b) circumduction (c) periduction (d) pronation Copyright 2014 Wolters Kluwer Health | Lippincott Williams & Wilkins Pretest 5. The opposite of abduction is: (a) adduction (b) circumduction (c) periduction (d) pronation Copyright 2014 Wolters Kluwer Health | Lippincott Williams & Wilkins Pretest 6. The band of connective tissue that attaches a muscle to a bone is a: (a) cartilage (b) bursa (c) tendon (d) diaphysis Copyright 2014 Wolters Kluwer Health | Lippincott Williams & Wilkins Pretest 6. The band of connective tissue that attaches a muscle to a bone is a: (a) cartilage (b) bursa (c) tendon (d) diaphysis Copyright 2014 Wolters Kluwer Health | Lippincott Williams & Wilkins Pretest 7. Polymyositis is inflammation of many: (a) sense organs (b) muscles (c) glands (d) bones Copyright 2014 Wolters Kluwer Health | Lippincott Williams & Wilkins Pretest 7. Polymyositis is inflammation of many: (a) sense organs (b) muscles (c) glands (d) bones Copyright 2014 Wolters Kluwer Health | Lippincott Williams & Wilkins Pretest 8. The word kinesis means: (a) movement (b) bending (c) stretching (d) pain Copyright 2014 Wolters Kluwer Health | Lippincott Williams & Wilkins Pretest 8. The word kinesis means: (a) movement (b) bending (c) stretching (d) pain Copyright 2014 Wolters Kluwer Health | Lippincott Williams & Wilkins Roots Pertaining to Muscles Root Meaning Example Definition of Example my/o muscle myositis* inflammation of muscle muscul/o muscle musculature muscle arrangement in a part or the whole body in/o fiber inotropic acting on (muscle) fibers fasci/o fascia fasciodesis
binding (suture) of a fascia to a tendon or other fascia * Note addition of s to this root before the suffix itis. Copyright 2014 Wolters Kluwer Health | Lippincott Williams & Wilkins Roots Pertaining to Muscles (contd) Root Meaning Example Definition of Example ten/o, tendin/o tendon tenostosis ossification of a tendon ton/o tone cardiotonic
having a strengthening action on the heart erg/o work ergonomics study of the efficient use of energy during work kin/o-, kine, kinesi/o, kinet/o movement kinesis
movement (adjective: kinetic) Copyright 2014 Wolters Kluwer Health | Lippincott Williams & Wilkins Types of Muscles Smooth Walls of hollow organs and ducts Operates involuntarily Responsible for peristalsis Cardiac Myocardium of heart wall Functions involuntarily Responsible for pumping of heart
Copyright 2014 Wolters Kluwer Health | Lippincott Williams & Wilkins Types of Muscles (contd) Skeletal Attaches to bones Responsible for voluntary movement Maintains posture Generates large portion of body heat Copyright 2014 Wolters Kluwer Health | Lippincott Williams & Wilkins Muscle Structure Fibers held together in fascicles Fascia covers muscle Tendons attach muscles to bones
Copyright 2014 Wolters Kluwer Health | Lippincott Williams & Wilkins Copyright 2014 Wolters Kluwer Health | Lippincott Williams & Wilkins Muscle Action Skeletal muscles stimulated by motor neurons of nervous system Acetylcholine released Prompts contraction Requires actin and myosin to interact ATP and calcium needed for this response Partial contraction = tonus
Copyright 2014 Wolters Kluwer Health | Lippincott Williams & Wilkins Muscle Action (contd) Muscles work in pairs at joints to produce movement Agonist = contraction Antagonist = relaxation Point of origin = muscle attachment point to stable part of skeleton Point of insertion = muscle attachment point to moving part of skeleton
Copyright 2014 Wolters Kluwer Health | Lippincott Williams & Wilkins Neuromuscular Junction Copyright 2014 Wolters Kluwer Health | Lippincott Williams & Wilkins Copyright 2014 Wolters Kluwer Health | Lippincott Williams & Wilkins Origins and Insertions Copyright 2014 Wolters Kluwer Health | Lippincott Williams & Wilkins Copyright 2014 Wolters Kluwer Health | Lippincott Williams & Wilkins Naming of Muscles Named by: Location Direction of fibers Size Shape Number of attachment heads Indicated by suffix -ceps Its action Indicated by suffix -or
Copyright 2014 Wolters Kluwer Health | Lippincott Williams & Wilkins Superficial Muscles, Anterior Copyright 2014 Wolters Kluwer Health | Lippincott Williams & Wilkins Copyright 2014 Wolters Kluwer Health | Lippincott Williams & Wilkins Superficial Muscles, Posterior Copyright 2014 Wolters Kluwer Health | Lippincott Williams & Wilkins Copyright 2014 Wolters Kluwer Health | Lippincott Williams & Wilkins Key Terms Normal Structure and Function Term Meaning acetylcholine (ACh) A neurotransmitter that stimulates contraction of skeletal muscles actin One of the two contractile proteins in muscle cells; the other is myosin agonist The muscle that carries out a given movement; prime mover antagonist The muscle that opposes an agonist (prime mover); it must relax when the agonist contracts cardiac muscle Involuntary muscle that makes up the wall of the heart fascia The fibrous sheath of connective tissue that covers a muscle; called deep fascia to differentiate it from the superficial fascia that underlies the skin (root: fasci/o); plural: fasciae fascicle A small bundle, as of muscle or nerve fibers insertion In a given movement, the point where a muscle is attached to a moving part of the skeleton muscle An organ that produces movement by contracting; also the tissue that composes such organs (root: my/o, muscul/o) Copyright 2014 Wolters Kluwer Health | Lippincott Williams & Wilkins Key Terms Normal Structure and Function (contd) Term Meaning myosin One of the two contractile proteins in muscle cells; the other is actin neuromuscular junction (NMJ) The point of contact, or synapse, between a branch of a motor neuron and a muscle cell origin In a given movement, the point where a muscle is attached to a stable part of the skeleton skeletal muscle Voluntary muscle that moves the skeleton and maintains posture smooth muscle Involuntary muscle that makes up the wall of the hollow organs, vessels, and ducts; visceral muscle synergist A muscle that assists an agonist to produce a given movement tendon A fibrous band of connective tissue that attaches a muscle to a bone (root: ten/o, tendin/o) tonus A state of steady, partial contraction of muscle that maintains firmness; muscle tone (root: ton/o) Copyright 2014 Wolters Kluwer Health | Lippincott Williams & Wilkins Clinical Aspects of the Muscular System Myopathy is a disorder of the muscles Techniques for diagnosing: Study of muscle in action Electromyography (EMG) Serum assay of enzymes released in damaged muscles Creatine kinase
Copyright 2014 Wolters Kluwer Health | Lippincott Williams & Wilkins Muscular Dystrophy Group of hereditary diseases Most common is Duchenne muscular dystrophy Progressive, noninflammatory degeneration of muscles Muscle tissue weakens and wastes away Gradually replaced with connective tissue and fat May co-exist with: Cardiomyopathy (disease of cardiac muscle) Mental impairment
Copyright 2014 Wolters Kluwer Health | Lippincott Williams & Wilkins Polymyositis Inflammation of skeletal muscle leading to weakness Dysphagia Cardiac problems Cause unknown May be related to viral infection or autoimmunity Often associated with other systemic diseases Rheumatoid arthritis Lupus erythematosus Copyright 2014 Wolters Kluwer Health | Lippincott Williams & Wilkins Polymyositis (contd) If skin is involved it is known as dermatomyositis Symptoms Erythema Dermatitis Lilac-colored rash Diagnosis Enzyme studies EMG Muscle biopsy
Copyright 2014 Wolters Kluwer Health | Lippincott Williams & Wilkins Fibromyalgia Syndrome Often associated with: Widespread muscle aches Tenderness Stiffness Fatigue Sleep disorders Difficult to diagnose Treatment Exercise program Pain relievers, muscle relaxants, antidepressants
Copyright 2014 Wolters Kluwer Health | Lippincott Williams & Wilkins Chronic Fatigue Syndrome Persistent fatigue of no known cause Associated with: Impaired memory Sore throat Painful lymph nodes Muscle and joint pain Headaches Sleep problems Immune disorders Often occurs after viral infection No consistent successful treatments
Copyright 2014 Wolters Kluwer Health | Lippincott Williams & Wilkins Myasthenia Gravis Acquired autoimmune disease Antibodies interfere with muscle stimulation at neuromuscular junction Progressive loss of muscle power Especially in: External eye muscles Other facial muscles Copyright 2014 Wolters Kluwer Health | Lippincott Williams & Wilkins Amyotrophic Lateral Sclerosis Lou Gehrig disease Progressive degeneration of motor neurons, leads to muscular atrophy Signs: Weakness Cramping Muscle twitching Eventually leads to death
Copyright 2014 Wolters Kluwer Health | Lippincott Williams & Wilkins Stress Injuries Include: Accidental injuries Damage caused by overexertion or repetitive motion (RSI) Damage to soft tissue: Muscle strain Inflammation Tearing of ligaments and tendons Bursitis
Copyright 2014 Wolters Kluwer Health | Lippincott Williams & Wilkins Stress Injuries (contd) Tendonitis is an inflammation of tendon, tendon sheath, and synovial membrane at joint Signs: pain, fatigue, weakness, stiffness, numbness, range of motion (ROM) Treatment: rest, elevation, ice packs, bracing, medications If more severe: steroid injections, ultrasound for deep heat, strength exercises, surgery, PT
Copyright 2014 Wolters Kluwer Health | Lippincott Williams & Wilkins Common Upper Extremity Conditions
Copyright 2014 Wolters Kluwer Health | Lippincott Williams & Wilkins Carpal Tunnel Syndrome Copyright 2014 Wolters Kluwer Health | Lippincott Williams & Wilkins Copyright 2014 Wolters Kluwer Health | Lippincott Williams & Wilkins Common Lower Extremity Conditions
Hamstring strain Shin splint Achilles tendonitis
Copyright 2014 Wolters Kluwer Health | Lippincott Williams & Wilkins Key Terms Disorders Term Meaning amyotrophic lateral sclerosis (ALS) A disease caused by degeneration of motor neurons resulting in muscular weakness and atrophy; Lou Gehrig disease chronic fatigue syndrome (CFS) A disease of unknown cause that involves persistent fatigue, along with muscle and joint pain and other symptoms; may be virally induced dermatomyositis A disease of unknown origin involving inflammation of muscles as well as dermatitis and skin rashes fibromyalgia syndrome (FMS) A disorder associated with widespread muscular aches and stiffness and having no known cause muscular dystrophy A group of hereditary muscular disorders marked by progressive weakness and atrophy of muscles myasthenia gravis (MG) A disease characterized by progressive muscular weakness; an autoimmune disease affecting the neuromuscular junction Copyright 2014 Wolters Kluwer Health | Lippincott Williams & Wilkins Key Terms Disorders (contd) Term Meaning polymyositis A disease of unknown cause involving muscle inflammation and weakness repetitive strain injury Tissue damage caused by repeated motion, usually overuse of the arm or hand in occupational activities such as writing, typing, painting, or using hand tools; also called repetitive motion injury, cumulative trauma injury, overuse syndrome sprain Injury to a ligament caused by abnormal or excessive force at a joint, but without bone dislocation or fracture strain Trauma to a muscle because of overuse or excessive stretch; if severe, may involve tearing of muscle, bleeding, or separation of muscle from its tendon or separation of a tendon from bone tendinitis Inflammation of a tendon, usually caused by injury or overuse; the shoulder, elbow, and hip are common sites; also spelled tendonitis tenosynovitis Inflammation of a tendon sheath Copyright 2014 Wolters Kluwer Health | Lippincott Williams & Wilkins Key Terms Diagnosis Term Meaning creatine kinase (CK) An enzyme found in muscle tissue; the serum level of CK increases in cases of muscle damage; creatine phosphokinase (CPK) electromyography (EMG) Study of the electrical activity of muscles during contraction Copyright 2014 Wolters Kluwer Health | Lippincott Williams & Wilkins Supplementary Terms Normal Structure and Function Term Meaning aponeurosis A flat, white, sheetlike tendon that connects a muscle with the part that it moves creatine A substance in muscle cells that stores energy for contraction glycogen A complex sugar that is stored for energy in muscles and in the liver isometric Pertaining to a muscle action in which the muscle tenses but does not shorten (literally: same measurement) isotonic Pertaining to a muscle action in which the muscle shortens to accomplish movement (literally: same tone) kinesthesia Awareness of movement; perception of the weight, direction, and degree of movement (-esthesia means sensation) Copyright 2014 Wolters Kluwer Health | Lippincott Williams & Wilkins Supplementary Terms Normal Structure and Function (contd) Term Meaning lactic acid An acid produced in muscle cells that accumulates in muscle cells functioning without enough oxygen (anaerobically), as in times of great physical exertion motor unit A single motor neuron and all of the muscle cells that its branches stimulate myoglobin A pigment similar to hemoglobin that stores oxygen in muscle cells Copyright 2014 Wolters Kluwer Health | Lippincott Williams & Wilkins Supplementary Terms Symptoms and Conditions Term Meaning asterixis Rapid, jerky movements, especially in the hands, caused by intermittent loss of muscle tone asthenia Weakness (prefix a- meaning without with root sthen/o meaning strength) ataxia Lack of muscle coordination (from root tax/o meaning order, arrangement); adjective: ataxic athetosis A condition marked by slow, irregular, twisting movements, especially in the hands and fingers; adjective: athetotic atrophy A wasting away; a decrease in the size of a tissue or organ, such as the wasting of muscle from disuse avulsion Forcible tearing away of a part clonus Alternating spasmodic contraction and relaxation in a muscle; adjective: clonic contracture Permanent contraction of a muscle Copyright 2014 Wolters Kluwer Health | Lippincott Williams & Wilkins Supplementary Terms Symptoms and Conditions (contd) Term Meaning fasciculation Involuntary small contractions or twitching of muscle fiber groups (fasciculi) fibromyositis A nonspecific term for pain, tenderness, and stiffness in muscles and joints fibrositis Inflammation of fibrous connective tissue, especially the muscle fasciae; marked by pain and stiffness restless legs syndrome (RLS) Uneasiness, twitching, or restlessness in the legs that occurs after going to bed and often leading to insomnia; may be caused by poor circulation or drug side effects rhabdomyolysis An acute disease involving diffuse destruction of skeletal muscle cells (root rhabd/o means rod, referring to the long, rodlike muscle cells) rhabdomyoma A benign tumor of skeletal muscle rhabdomyosarcoma A highly malignant tumor of skeletal muscle Copyright 2014 Wolters Kluwer Health | Lippincott Williams & Wilkins Supplementary Terms Symptoms and Conditions (contd) Term Meaning rheumatism A general term for inflammation, soreness, and stiffness of muscles associated with pain in joints (adjective: rheumatic, rheumatoid) spasm A sudden, involuntary muscle contraction; may be clonic (contraction alternating with relaxation) or tonic (sustained); a strong and painful spasm may be called a cramp (adjectives, spastic, spasmodic) spasticity Increased tone or contractions of muscles causing stiff and awkward movements tetanus An acute infectious disease caused by the anaerobic bacillus Clostridium tetani. It is marked by persistent painful spasms of voluntary muscles; lockjaw tetany A condition marked by spasms, cramps, and muscle twitching caused by a metabolic imbalance, such as low blood calcium caused by underactivity of the parathyroid glands torticollis Spasmodic contraction of the neck muscles causing stiffness and twisting of the neck; wryneck Copyright 2014 Wolters Kluwer Health | Lippincott Williams & Wilkins Supplementary Terms Diagnosis and Treatment Term Meaning Chvostek sign Spasm of facial muscles after a tap over the facial nerve; evidence of tetany occupational therapy Health profession concerned with increasing function and preventing disability through work and play activities. The goal of occupational therapy is to increase the patient's independence and quality of daily life physical therapy Health profession concerned with physical rehabilitation and prevention of disability. Exercise, massage, and other therapeutic methods are used to restore proper movement rheumatology The study and treatment of rheumatic diseases Trousseau sign Spasmodic contractions caused by pressing the nerve supplying a muscle; seen in tetany Copyright 2014 Wolters Kluwer Health | Lippincott Williams & Wilkins Supplementary Terms Drugs Term Meaning antiinflammatory agent Drug that reduces inflammation; includes steroids, such as cortisone, and nonsteroidal antiinflammatory drugs COX-2 inhibitor Nonsteroidal antiinflammatory drug that does not cause the stomach problems associated with other NSAIDs. Inhibits the cyclooxygenase (COX)-2 enzyme without affecting the COX-1 enzyme, a lack of which can cause stomach ulcers. Some of these drugs have been withdrawn from the market because of cardiac risk. Example is celecoxib (Celebrex) muscle relaxant A drug that reduces muscle tension; different forms may be used to relax muscles during surgery, to control spasticity, or to relieve musculoskeletal pain nonsteroidal antiinflammatory drug (NSAID) Drug that reduces inflammation but is not a steroid; examples include aspirin, ibuprofen, naproxen, and other inhibitors of prostaglandins, naturally produced substances that promote inflammation Copyright 2014 Wolters Kluwer Health | Lippincott Williams & Wilkins Abbreviations Ach Acetylcholine ALS Amyotrophic lateral sclerosis CFS Chronic fatigue syndrome C(P)K Creatine (phospho)kinase CTS Carpal tunnel syndrome EMG Electromyography, electromyogram FMS Fibromyalgia syndrome MG Myasthenia gravis MMT Manual muscle test(ing) Copyright 2014 Wolters Kluwer Health | Lippincott Williams & Wilkins Abbreviations (contd) NMJ Neuromuscular junction OT Occupational therapy/therapist PT Physical therapy/therapist RICE Rest, ice, compression, elevation RLS Restless legs syndrome ROM Range of motion RSI Repetitive strain injury RTC Rotator cuff SITS Supraspinatus, infraspinatus, teres minor, subscapularis (muscles) Copyright 2014 Wolters Kluwer Health | Lippincott Williams & Wilkins Post Test Underline the term that best fits the definition: 1. Movement away from the midline of the body: (abduction, adduction) 2. Fibrous band of connective tissue that connects muscle to bone: (tendon, fascia) 3. Muscle that carries out a given movement: (antagonist, agonist) Copyright 2014 Wolters Kluwer Health | Lippincott Williams & Wilkins Post Test Underline the term that best fits the definition: 1. Movement away from the midline of the body: (abduction, adduction) 2. Fibrous band of connective tissue that connects muscle to bone: (tendon, fascia) 3. Muscle that carries out a given movement or a prime mover: (antagonist, agonist) Copyright 2014 Wolters Kluwer Health | Lippincott Williams & Wilkins Post Test Fill in the blank with the best term. 4. ____________ is an acquired autoimmune disease in which antibodies interfere with muscle stimulation at the NMJ. 5. Injury to a ligament caused by abnormal or excessive force at a joint, but without bone dislocation or fracture is known as a(n) ____________.
Copyright 2014 Wolters Kluwer Health | Lippincott Williams & Wilkins Post Test Fill in the blank with the best term. 4. Myasthenia gravis is an acquired autoimmune disease in which antibodies interfere with muscle stimulation at the NMJ. 5. Injury to a ligament caused by abnormal or excessive force at a joint, but without bone dislocation or fracture is known as a(n) sprain.