Escolar Documentos
Profissional Documentos
Cultura Documentos
Learning Outcomes
Discuss how the evolutionary race between
pathogens and their hosts has resulted in
sophisticated evasion mechanisms in Human
Immunodeficiency Virus (HIV)
Transcription vs Translation
Transcription = synthesis of mRNA from a DNA template
Translation = Ribosomes use mRNA to synthesise new
proteins
Sort cards into correct order to remind yourself of protein
synthesis
Protein Synthesis
(again!)
Translation
Reverse Transcription
The Virus uses an enzyme called reverse transcriptase to copy viral RNA into
viral DNA
Integrase then inserts viral DNA into host DNA which enters the host nucleus
In the nucleus viral DNA produces viral mRNA
Reverse transcription
Integrase
Protein synthesis Viral envelope
Viral RNAmRNA
Viral DNACD4 receptors
Budding gp120 receptors
Integration
Infection
Reverse transcriptase
Home learning
1.
2.
3.
4.
5.
6.
7.
BINGO!
Transcription
Disease phase
Degenerative code
Acute phase
Amino acids
Translation
RNA Polymerase
Codon
tRNA
Reverse
Transcriptase
T helper cell
Condensation
reaction
CD4 receptors
Chronic phase
mRNA
Integrase