Escolar Documentos
Profissional Documentos
Cultura Documentos
Learning Objectives
Discuss common medication errors that
occur in pediatric and neonatal patient care
Describe error reduction strategies for the
pediatric and neonatal populations
Explain limitations of automated medication
error reduction devices in these
populations
Describe the role of the interdisciplinary
team in preventing medication errors
Incidence of
Adverse Drug Events
Medication error rate: pediatric error rates
approximately equal to adult error rates
Errors in pediatrics are 3 times more likely to
be associated with a potential ADE
Neonatal ICU: patient group with highest
error and potential ADE rate
74% of errors and 79% of potential ADEs
occur in ordering phase
Fortescue E, et al. Pediatrics. 2003;111(4 pt 1):7229.
Kaushal R, et al. JAMA. 2001;285:211420.
Market limitations
Cost of testing may outweigh expected market
Market share typically less than in adult market
Less financial incentive to manufacturers for most
disease states
Sources of Errors
Confusion between adult and pediatric
formulations
Confusion among oral liquid
concentrations
Look-alike and sound-alike packaging
and names
Multiple dosing styles
Look-Alike, Sound-Alike
Medication names
Medication packaging
Confusion between IV and oral products
This problem has increased in pediatrics as
practice of using IV medication for oral
administration has increased
Additional Information on
Look-Alike and Sound-Alike
Medications and Packaging
Available in Slide Deck for
Chapters 6 and 7
Calculation Errors
Misuse of decimals
Wrong
Right
.1 mg
0.1 mg
1.0 mg
1 mg
Way to remember: if the decimal is not seen,
10-fold error might be made
Calculation Errors
Single dose divided by frequency
3 mg/kg every 8 hours
Example: 10 kg patient
Example: 10 kg patient
Calculation Errors
Errors in unit conversion
Miscalculation of body surface area
Misplaced decimals
Compounded errors: 10-fold errors
Insulin Dilution
For insulin doses 5 units
May use the 100 units/mL concentration
Rule of 6
The Rule of 6 is an equation used to
calculate the amount of drug to add to
100 mL of IV fluid so that an infusion rate
of 1 mL/hr will deliver 1 mcg/kg/min
6 x weight (kg) = amount of drug (mg)
100 mL of solution
Drug waste
Strategies for
Medication Error Reduction
Staff Competencies
Require math competencies for all staff
Develop competencies for entire team before
new service is implemented
Provide resources for maintaining competency
for pediatric and neonatal pharmacology
Ensure competency on all staffing shifts
Patient Information
Provide patient age and date of birth
Decreases risk of confusing age in years versus
months
0.1 (right)
.1 (wrong)
1 (right)
1.0 (wrong)
Reduction of
Administration Errors
Oral liquids
Dispense in unit of use
Oral syringes
Dispensing bottles
Reduction of
At-Home Administration Errors
Dispense appropriate measuring device with
each prescription and refill
Review dosing instructions with caregivers
Suggest a 1 caregiver administration policy
Prevents overdoses by well-meaning multiple
caregivers administering doses
Medication Safety in
Pediatric Emergencies
Broselow tape
Measuring tape placed next to a supine child
Based on childs length, tape estimates childs weight
Medication Safety in
Pediatric Emergencies
Provide age-appropriate code trays
Adult, pediatric, neonatal
Set appropriate par levels
Pre-Procedure Sedation
Often prescribed for administration at home
prior to arrival at physicians office
Chloral hydrate and benzodiazepines most
common
Automation
Automated Dispensing Cabinets (ADC)
Bar Code Point of Care (BPOC)
Computerized Prescriber Order Entry
(CPOE)
Smart Infusion Pumps
Role of Automation in
Pediatric and Neonatal Services
Safety
CPOE: Ability to check prescribed doses
against patient weight
ADCs make dosages available for emergent
or after hours use
Bar coding checks for correct patient, drug,
dose, dosage form, and time at point of drug
administration
Smart infusion pumps allow for safety checks
on standard concentrations prior to infusion
Pitfalls of Automation in
Pediatric and Neonatal Services
CPOE
Data are only as accurate as information
entered
Correct patient weight may not be in system
Labels may not be appropriate for pediatric
dosage forms
Pitfalls of Automation in
Pediatric and Neonatal Services
ADCs
Medications requiring further preparation or measurement by the
nurse may be stored in ADC
Drugs may be obtained before pharmacist review (override)
When accessing one particular drug, nurse may have access to
other drugs
Additional Information on
Automation
Available in Slide Deck for
Chapter 15
References
Cohen MR. Medication Errors. Causes, Prevention, and
Risk Management; 11.111.16.
Fortescue E, Kaushal R, Landrigan CP, et al. Prioritizing
strategies for preventing medication errors and adverse
drug events in pediatric inpatients. Pediatrics.
2003;111(4 pt 1):7229.
Institute for Safe Medication Practices. Safety briefs. ISMP
Medication Safety Alert! February 26, 1997;2:1.
Kaushal R, Bates DW, Landrigan C, et al. Medication errors
and adverse drug events in pediatric inpatients. JAMA.
2001;285:211420.