SAHS BIOSTATISTICS

TUTORIALS

DNA
In a study of iron deficiency among
infants,
random samples of infants
following different
feeding programs were compared.
One group
contained breast-fed infants, while
the children
in another group were fed by a
standard baby
formula without any iron
supplements.
Here are summary results of blood
hemoglobin levels at 12 months of
age.

Group N X SD
Breast-fed 8 13.3 1.7
Formula-fed 10 12.4 1.8
1.State the null hypothesis
2.State the alternate hypothesis
3.State the appropriate test
statistic to use
4.Test at 95% level of significance
whether the two feeding
Trace metals in drinking water wells
affect the flavor
of the water and unusually high
concentrations can
pose a health hazard. Furthermore,
the water in well
may vary in the concentration of the
trace metals depending upon from
where it is drawn. Trace metal
concentrations (mg/L) on zinc were
found from
water drawn from the bottom and the
Location Bottom Top
1 .430 .415
2 .266 .
238
3 .567 .
390
4 .531 .
410
5 .707 .
605
1.State the null hypothesis
2.State the alternate
hypothesis
3.State the appropriate test
statistic to use
4.Test at 95% level of
significance whether the
trace metal concentration of
zinc at the two levels be
significantly different.
A survey was conducted to
investigate the
severity of rodent problems in egg
and poultry
operations. A random sample of
operators was
selected, and the operators were
classified
according to the type of operation
and the extent
of the rodent population. A total of
78 egg
1.State the null hypothesis
2.State the alternate hypothesis
3.State the appropriate test statistic
to use
4.Test at 95% whether there is any
association between the type of
operation and the extent of
rodent population.
Restenosis– narrowing of the blood
vessels – frequently occurs after
coronary angioplasty, but accurate
prediction of which individuals will
have this problem is problematic. In a
study conducted in 1993, the
investigators hypothesized that
restenosisis more likely to occur if
activated smooth-muscle cells in
coronary lesions at the time of
surgery are present. They used the
number of reactive nuclei in the
coronary lesions as an indicator of the
presence of the activated smooth-
Patient Degree of Stenosis (%) at Number of Reactive Nuclei
Follow-up at Initial Surgery
1 28 5
2 15 3
3 22 2
4 93 10
5 60 12
6 90 25
7 42 8
8 53 3
9 72 15
10 0 13
11 79 17
12 28 0
13 82 13
14 28 14
15 100 17
16 21 1
1. Construct a scatter plot for these
data.
2. Using the least squares method,
find the best fitting linear relationship
between number of reactive nuclei in
the lesions and the degree of
stenosis.
3. Interpret the slope and intercept in
terms of the problem.
4. What is R2 for this regression and
interpret your results.
5. What is the expected degree of
stenosis for a new subject who
presents with number of reactive
nuclei in the coronary lesions equal to
33?