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Gastritis
Result of a breakdown in gastric
mucosal barrier
Stomach tissue unprotected
from autodigestion by HCl acid
and pepsin
Copyright 2007, 2004, 2000, Mosby, Inc., an affiliate of Elsevier Inc. All Rights Reserved.
Gastritis
Tissue edema results
Disruption of capillary walls
With loss of plasma into gastric
lumen
Possible hemorrhage
Copyright 2007, 2004, 2000, Mosby, Inc., an affiliate of Elsevier Inc. All Rights Reserved.
Gastritis
Etiology and Pathophysiology
Risk factors
Drugs
Direct irritating effect on gastric
mucosa
Aspirin, NSAIDs, and
corticosteroids
Diet
Alcohol, spicy food
Copyright 2007, 2004, 2000, Mosby, Inc., an affiliate of Elsevier Inc. All Rights Reserved.
Gastritis
Etiology and Pathophysiology
Risk factors (contd)
Microorganisms
Helicobacter pylori
Important cause of chronic gastritis
Promotes breakdown of gastric
mucosal barrier
Staphylococcus organisms
Copyright 2007, 2004, 2000, Mosby, Inc., an affiliate of Elsevier Inc. All Rights Reserved.
Gastritis
Etiology and Pathophysiology
Risk factors (contd)
Environmental factors
Radiation, smoking
Pathophysiologic conditions
Burns, renal failure, sepsis
Other factors
Psychologic stress, NG tube
Copyright 2007, 2004, 2000, Mosby, Inc., an affiliate of Elsevier Inc. All Rights Reserved.
Gastritis
Etiology and Pathophysiology
Risk factors (contd)
Autoimmune atrophic gastritis
Affects fundus and body of stomach
Associated with increased risk of
gastric cancer
May be link to presence of H. pylori
and development of autoimmune
chronic gastritis
Copyright 2007, 2004, 2000, Mosby, Inc., an affiliate of Elsevier Inc. All Rights Reserved.
Acute Gastritis
Clinical Manifestations
Self-limiting
Lasts few hours to a few days
Complete healing of mucosa
expected
Copyright 2007, 2004, 2000, Mosby, Inc., an affiliate of Elsevier Inc. All Rights Reserved.
Acute Gastritis
Clinical Manifestations
Anorexia
Nausea
Vomiting
Epigastric tenderness
Feeling of fullness
Hemorrhage
Common with alcohol abuse
May be only symptom
Copyright 2007, 2004, 2000, Mosby, Inc., an affiliate of Elsevier Inc. All Rights Reserved.
Chronic Gastritis
Clinical Manifestations
Symptoms are similar to acute
gastritis
Loss of intrinsic factor can occur
when acid-secreting cells are lost
or are nonfunctioning
Essential for absorption of
cobalamin (vitamin B12)
Copyright 2007, 2004, 2000, Mosby, Inc., an affiliate of Elsevier Inc. All Rights Reserved.
Gastritis
Diagnostic Studies
Acute gastritis
Diagnosis most often based on
Chronic gastritis
Diagnosis may be delayed or
Gastritis
Diagnostic Studies
Endoscopic examination with
biopsy
Necessary for definitive diagnosis
Copyright 2007, 2004, 2000, Mosby, Inc., an affiliate of Elsevier Inc. All Rights Reserved.
Gastritis
Diagnostic Studies
Radiologic studies not helpful
CBC
Confirm presence of anemia
Copyright 2007, 2004, 2000, Mosby, Inc., an affiliate of Elsevier Inc. All Rights Reserved.
Gastritis
Diagnostic Studies
Gastric analysis
Determines achlorhydria (lack of acid
secretion)
Associated with severe atrophic
gastritis
Copyright 2007, 2004, 2000, Mosby, Inc., an affiliate of Elsevier Inc. All Rights Reserved.
Gastritis
Diagnostic Studies
Tissue biopsy with cytologic
examination
Rule out gastric carcinoma
Copyright 2007, 2004, 2000, Mosby, Inc., an affiliate of Elsevier Inc. All Rights Reserved.
Acute Gastritis
Collaborative Care
Supportive care similar to N/V
If vomiting
NPO
Fluids
Dehydration can occur rapidly
Rest
Antiemetics
Copyright 2007, 2004, 2000, Mosby, Inc., an affiliate of Elsevier Inc. All Rights Reserved.
Acute Gastritis
Collaborative Care
NG tubeif severe symptoms
Observe for bleeding
Lavage of precipitating agent from
stomach
Keep stomach empty and free of
noxious stimuli
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Acute Gastritis
Collaborative Care
If hemorrhage likely
Frequent VS
Testing vomitus for blood
Copyright 2007, 2004, 2000, Mosby, Inc., an affiliate of Elsevier Inc. All Rights Reserved.
Acute Gastritis
Collaborative Care
Drug therapy
Focused on reducing irritation of
mucosa
Providing symptomatic relief
Copyright 2007, 2004, 2000, Mosby, Inc., an affiliate of Elsevier Inc. All Rights Reserved.
Acute Gastritis
Collaborative Care
Drug therapy
Antacids, H2R blockers, PPIs,
combinations
Nurse must teach patient about
medications and side effects
Copyright 2007, 2004, 2000, Mosby, Inc., an affiliate of Elsevier Inc. All Rights Reserved.
Chronic Gastritis
Collaborative Care
Focuses on evaluating and
eliminating cause
H. pyloriantibiotics
Pernicious anemiacobalamin
supplements
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Chronic Gastritis
Collaborative Care
Lifestyle changes
Diet
Alcohol
Smoking
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Nursing Diagnosis
1.
-the nurse can help the client identify food that stimulate development of gastritis&
incourage the client to avoid these agent*
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