than 2.5 standard deviations (SDs) below the mean for age. The penis grows very little until puberty when testosterone levels begin to rise.
PATHOPHYSIOLOGI
Fetal production of testosterone and its
peripheral conversion to dihydrotestosterone (DHT) is necessary for normal male development. After birth, gonadotropin (luteinizing hormone [LH] and follicle stimulating hormone [FSH]) and testosterone production decrease.
Beginning at about age 1 week, gonadotropin
and testosterone levels begin to rise again to pubertal levels, peaking at age 1-3 months Decreasing to prepubertal levels by age 6 months.
Genetic syndromes in which micropenis may
be a feature include Prader-Willi, Klinefelter, and Noonan syndromes
TREATMENT
Testosterone therapy in the form of 3-6
monthly intramuscular (IM) injections Testosterone therapy has generally been found effective in treating micropenis due to testosterone deficiency.