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Injectable
Medications
Heather Fackelman
Regular Insulin
Humulin R, Novolin R
Onset: 30-60 minutes
Peak: 2-5 hours
Duration: 3-6 hours
Mealtime Insulin
Background Insulin
NPH (Neutral Protamine Hagedorn) (Humulin N,
Novolin N)
Onset: 2-4 hours
Peak: 4-10 hours
Duration: 10-16 hours
Background Insulin
Amylin Analogue
Pramlintide (Symlin)
Mechanism of Action: slows gastric emptying,
inhibits glucagon secretion, and raises the acute
first-phase insulin response threshold after meals
Side Effects: nausea, headache, increased risk of
hypoglycemia