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Current Methods
Full or partial removal of wound pad
Visual Observation
Skin Irritation
Increased chances of infection
Only qualitative information
Collecting biochemical information
Highly invasive
Expensive
The Business Case
Non-invasive
detector detector
Sensing layer
pH
Wound
The Team
1.5
exc. 460 nm / exc. 405 nm
1.0
Intensity ratio
0.5
Ion pair:
Pyranine-benzalkonium
HPTS-BZK on PVDF membrane
0.0
5.5 6.0 6.5 7.0 7.5 8.0 8.5
pH
Concept 2: dyeing
Perylene bisanhydride
+
Branched polyethyleneimine
The functional pad - I
Textile wound-pad
The functional pad - II
Dye solution
Dots with the fluorescent dyes
Textile wound-pad
Fluorescent detector
Dimensions: 30x30x10
mm3
Anodized aluminum
body
Interface / GUI
GRS proposal (TheranOptics Sarl, Empa, and CSEM, together with EPFL):
Development of a fully integrated lab-on-fiber fluorescence
platform for point-of-care testing of chronic wounds
pH = 5.9
Wound is ok
pH = 7.3
Go to
doctor
Thanks!