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ACUTE CORONARY

SYNDROME

Dr. Novita SpJP


MI is definined as myocardial
cell death due to prolonged
ischemia
20 mnt : cell death
histologically
Several hours : myocardial
necrosis
2 4 hours: complete
necrosis of myocardial cells
Risk Factors for
MODIFIABLE NON-MODIFIABLE
Cardiovascular PERSONAL
SMOKING Disease HISTORY OF CAD
DISLIPIDEMIA FAMILY HISTORY OF CAD
RAISED LDL AGE
CHOLESTEROL GENDER
LOW HDL CHOLESTEROL
RAISED TRIGLYCERIDE
RAISED BLOOD PRESSURE
DIABETES MELLITUS
OBESITY
DIETARY FACTORS
THROMBOGENIC FACTORS
LACK OF EXERCISE
EXCESS ALCOHOL
CONSUMPTION
Assessing Chest Pain
(Classic Angina)
LOCATION
RADIATION
CHARACTER
TIME OF ONSET, DURATION,
FREQUENCY
EXACERBATING AND
ALLEVIATING FACTORS
ASSOCIATED SYMPTOMS
Possible presentation of
Angina
Angina at rest, with pain
episodes lasting > 20 min
New onset ( within 2
months )exertional angina of
at least CCSC II
Recent increase (< 2
months ) in anginal severity
to at least CCSC III
Angina post MCI
Angina Pectoris
Stable : there is no
substantial deterioration in
symptom over several weeks.
Stability or quiescence of an
atherosclerotic plaque,
depending on increased
oxygen demand

Unstable : symptom pattern


worsen abruptly without an
obvious caused of increased
Angina Pectoris

Non Anginal caused of
chest pain
Musculosceletal disorders
GI disorders ( peptic ulcers )
Aortic dissection
Thoracic aneurysm
Esophageal spasm
Pneumonia
Pericarditis
Neuropsychiatric causes (eg.
Panic disorder )
Thank
You

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