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ALLERGIC RHINITIS

IN CHILDREN
Literature Reading
Rhinology

By
Rina Desdwi Utami S

Supervisor :
dr. Arif Dermawan, M.Kes, Sp.THT-KL(K)

Dept of Otorhinolaryngology - Head and Neck Surgery


Faculty of Medicine Universita Padjadjaran / Hasan Sadikin
General Hospital
Bandung
2017
INTRODUCTION

Allergic rhinitis (AR) is common in children

The prevalence has been reported to be 10-40% in


the pediatric population worldwide

AR is commonly under-diagnosed, with symptoms


frequently attributed to a recurrent common cold

Turner, Kemp. Allergic Rhinitis in Children. Journal of Paediatrics and Child Health. November 2010: 302-310

2
INTRODUCTION

Although allergic rhinitis is seldom a severe or life


threatening disease, it can have profound effects on
daily living and development of a child

AR has multiple comorbidities and is closely related


to asthma

Thomas S. Rhinitis in Children : Diagnosis of AR relles on history and physical exam; antigen testing confirms diagnosis
and directs treatment. SLU Care The Physicians of Saint Louis University. Missouri Medicine. Vol. 105. May/June 2008
3
INTRODUCTION

Often the childs parents will concentrate on


comorbid diseases only and will not mention or be
concerned by symptoms of their childs allergic
rhinitis

Diagnosis of AR is made by a combination of history


and physical exam

Thomas S. Rhinitis in Children : Diagnosis of AR relles on history and physical exam; antigen testing confirms diagnosis
and directs treatment. SLU Care The Physicians of Saint Louis University. Missouri Medicine. Vol. 105. May/June 2008
4
INTRODUCTION

Treatment of AR can include allergen avoidance,


pharmacotherapy and immunotherapy

All three therapies are effective and safe in children

Thomas S. Rhinitis in Children : Diagnosis of AR relles on history and physical exam; antigen testing confirms diagnosis
and directs treatment. SLU Care The Physicians of Saint Louis University. Missouri Medicine. Vol. 105. May/June 2008
5
INTRODUCTION

Nasal symptoms are one of the most common


complaints in the pediatric population. It is
estimated that about 50% of rhinitis is atopic in
nature

AR is the most common atopic disease and one of


the most frequent chronic conditions of children

Thomas S. Rhinitis in Children : Diagnosis of AR relles on history and physical exam; antigen testing confirms diagnosis
and directs treatment. SLU Care The Physicians of Saint Louis University. Missouri Medicine. Vol. 105. May/June 2008
6
INTRODUCTION

It is interesting that these figures are found


primarily in industrial nations and are less evident in
developing countries

The factors that cause these differences are not clear,


but likely involve genetic and environmental
mechanisms

Thomas S. Rhinitis in Children : Diagnosis of AR relles on history and physical exam; antigen testing confirms diagnosis
and directs treatment. SLU Care The Physicians of Saint Louis University. Missouri Medicine. Vol. 105. May/June 2008
7
INTRODUCTION

One possible explanation for the differences in these


respective populations is the Hygiene hypothesis

Thomas S. Rhinitis in Children : Diagnosis of AR relles on history and physical exam; antigen testing confirms diagnosis
and directs treatment. SLU Care The Physicians of Saint Louis University. Missouri Medicine. Vol. 105. May/June 2008
8
Patogenesis Allergic Rhinitis:
9

Scadding. Allergic Rhinitis in Children. Paediatrics and Child Health. 2008; 18:7,323-29

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DEFINITION

Rhinitis an inflammation of the lining of the nose and is


characterized by nasal symptoms including anterior or
posterior rhinorhoea, sneezing, nasal blockage and/or itching
of the nose.

Allergic rhinitis the most common form of


noninfectious rhinitis and is associated with an IgE-mediated
immune response against allergens associated with ocular
symptoms.

Updated ARIA Recomendation 2008

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CLASSIFICATION
Of Allergic Rhinitis
Intermittent Persistent
Symptoms Symptoms
< 4 days per week > 4 days per week
or < 4 weeks at a time and > 4 weeks at a time

Moderate-severe
Mild one or more items
normal sleep abnormal sleep
no impairment of daily activities, impairment of daily activities, sport,
sport, leisure leisure
normal work and abnormal work and school
school troublesome symptoms
no troublesome symptoms

Updated ARIA Recomendation 2008


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Diagnosis in Primary Care Setting

Updated ARIA Recomendation 2008


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DIAGNOSIS

Clinical Course of Atopy and Rhinitis

One of the most common reasons for a child to


visit the physician is for chronic nasal airway
symptoms
The challenge for the physician is to find the
underlining cause and therapy for the child
Infections are the most common cause of acute
rhinitis in children

Sanford T. Rhinitis in Children : Diagnosis of AR relles on history and physical exam; antigen testing confirms diagnosis
and directs treatment. SLU Care The Physicians of Saint Louis University. Missouri Medicine. Vol. 105. May/June 2008
13
DIAGNOSIS

Clinical Course of Atopy and Rhinitis

Between the ages of 2-6 the average child has six


infections per year each lasting 7-10 days
Secondary infection occurs it can last 2-3 week
Recurrent infections can mimic the chronic
process of AR
Immunologic deficiencies can increase the
number and length of rhinology infections

Sanford T. Rhinitis in Children : Diagnosis of AR relles on history and physical exam; antigen testing confirms diagnosis
and directs treatment. SLU Care The Physicians of Saint Louis University. Missouri Medicine. Vol. 105. May/June 2008
14
DIAGNOSIS

Clinical Course of Atopy and Rhinitis

Sanford T. Rhinitis in Children : Diagnosis of AR relles on history and physical exam; antigen testing confirms diagnosis
and directs treatment. SLU Care The Physicians of Saint Louis University. Missouri Medicine. Vol. 105. May/June 2008
15
DIAGNOSIS

Clinical Course of Atopy and Rhinitis

Sanford T. Rhinitis in Children : Diagnosis of AR relles on history and physical exam; antigen testing confirms diagnosis
and directs treatment. SLU Care The Physicians of Saint Louis University. Missouri Medicine. Vol. 105. May/June 2008
16
DIAGNOSIS

Clinical Course of Atopy and Rhinitis

It is useful to keep in mind the age related


manifestations of AR and atopy in children; this
is often referred to as the Allergic March.

Children with atopy will often express the disease


in a progressive manor starting with eczema,
then asthma and finally AR

Sanford T. Rhinitis in Children : Diagnosis of AR relles on history and physical exam; antigen testing confirms diagnosis
and directs treatment. SLU Care The Physicians of Saint Louis University. Missouri Medicine. Vol. 105. May/June 2008
17
DIAGNOSIS
Allergic March

Weinberg E.G. The Allergic March. CME Vol 8, No 2. February 2010

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DIAGNOSIS

History

A complete history is integral to the diagnosis of


allergic rhinitis

To diagnose AR in children the physician should


evaluate the symptoms and comorbidities of the
child

Sanford T. Rhinitis in Children : Diagnosis of AR relles on history and physical exam; antigen testing confirms diagnosis
and directs treatment. SLU Care The Physicians of Saint Louis University. Missouri Medicine. Vol. 105. May/June 2008
19
DIAGNOSIS

History

Sanford T. Rhinitis in Children : Diagnosis of AR relles on history and physical exam; antigen testing confirms diagnosis
and directs treatment. SLU Care The Physicians of Saint Louis University. Missouri Medicine. Vol. 105. May/June 2008
20
DIAGNOSIS

History

Sanford T. Rhinitis in Children : Diagnosis of AR relles on history and physical exam; antigen testing confirms diagnosis
and directs treatment. SLU Care The Physicians of Saint Louis University. Missouri Medicine. Vol. 105. May/June 2008
21
DIAGNOSIS

History

A set of questions directed at these areas can be


used as a screening device to raise the suspicion
of AR diagnosis

Children with AR frequently miss school days,


have disruption of sleep with associated fatigue
and impaired concentration

Sanford T. Rhinitis in Children : Diagnosis of AR relles on history and physical exam; antigen testing confirms diagnosis
and directs treatment. SLU Care The Physicians of Saint Louis University. Missouri Medicine. Vol. 105. May/June 2008
22
DIAGNOSIS

History

Their ability to perform well in school and


extracurricular activities is also effected by AR

These challenges can cause emotional problems,


isolation and poor self-esteem.

Sanford T. Rhinitis in Children : Diagnosis of AR relles on history and physical exam; antigen testing confirms diagnosis
and directs treatment. SLU Care The Physicians of Saint Louis University. Missouri Medicine. Vol. 105. May/June 2008
23
DIAGNOSIS

History

Family history can also support the diagnosis of


AR. If both parents are affected by atopic disease
there is a 50% chance that the child will have AR

The percentage risk increases to 70% if the


parents symptoms are of the same type and
greater severity

Sanford T. Rhinitis in Children : Diagnosis of AR relles on history and physical exam; antigen testing confirms diagnosis
and directs treatment. SLU Care The Physicians of Saint Louis University. Missouri Medicine. Vol. 105. May/June 2008
24
DIAGNOSIS

History

Updated ARIA Recomendation 2008

25
DIAGNOSIS

Physical Exam

The physical exam of the AR child can be


variable but often some of the following are
identified

Children with AR often clear their throats and


develop a habit of rubbing their nose and eyes

Sanford T. Rhinitis in Children : Diagnosis of AR relles on history and physical exam; antigen testing confirms diagnosis
and directs treatment. SLU Care The Physicians of Saint Louis University. Missouri Medicine. Vol. 105. May/June 2008
26
DIAGNOSIS

Physical Exam

Their voice is often hyponasal and mildly hoarse.

Allergic salute

Dennies-lines

Allergic shiners

Sanford T. Rhinitis in Children : Diagnosis of AR relles on history and physical exam; antigen testing confirms diagnosis
and directs treatment. SLU Care The Physicians of Saint Louis University. Missouri Medicine. Vol. 105. May/June 2008
27
DIAGNOSIS

Physical Exam

Sanford T. Rhinitis in Children : Diagnosis of AR relles on history and physical exam; antigen testing confirms diagnosis
and directs treatment. SLU Care The Physicians of Saint Louis University. Missouri Medicine. Vol. 105. May/June 2008
28
DIAGNOSIS

Diagnostic Tests

The causative allergens are identified by allergy


testing. Allergy testing is done in vivo (skin
testing ) or in vitro (Rast testing)

Sanford T. Rhinitis in Children : Diagnosis of AR relles on history and physical exam; antigen testing confirms diagnosis
and directs treatment. SLU Care The Physicians of Saint Louis University. Missouri Medicine. Vol. 105. May/June 2008
29
DIAGNOSIS

Diagnostic Tests

Sanford T. Rhinitis in Children : Diagnosis of AR relles on history and physical exam; antigen testing confirms diagnosis
and directs treatment. SLU Care The Physicians of Saint Louis University. Missouri Medicine. Vol. 105. May/June 2008
30
THERAPY

Environmental Therapy

Avoidance of allergens is a first line therapy for


children with AR

The common allergens (pollen, mold, danders


and dust mites) are often ubiquitous and
therefore hard to avoid

Sanford T. Rhinitis in Children : Diagnosis of AR relles on history and physical exam; antigen testing confirms diagnosis
and directs treatment. SLU Care The Physicians of Saint Louis University. Missouri Medicine. Vol. 105. May/June 2008
32
THERAPY

Environmental Therapy

The general approach to avoidance is to establish


a safe zone within the childs home

This room should have minimal cloth and


carpeting to decrease collection of antigens and
minimize habitat for dust mites

Sanford T. Rhinitis in Children : Diagnosis of AR relles on history and physical exam; antigen testing confirms diagnosis
and directs treatment. SLU Care The Physicians of Saint Louis University. Missouri Medicine. Vol. 105. May/June 2008
33
THERAPY

Pharmacotherapy

The drug therapy of AR can be quite effective

antihistamines, intranasal steroids, leukotriene


inhibitors, decongestants.

Sanford T. Rhinitis in Children : Diagnosis of AR relles on history and physical exam; antigen testing confirms diagnosis
and directs treatment. SLU Care The Physicians of Saint Louis University. Missouri Medicine. Vol. 105. May/June 2008
34
THERAPY

Pharmacotherapy

Sanford T. Rhinitis in Children : Diagnosis of AR relles on history and physical exam; antigen testing confirms diagnosis
and directs treatment. SLU Care The Physicians of Saint Louis University. Missouri Medicine. Vol. 105. May/June 2008
35
THERAPY

Pharmacotherapy

Sanford T. Rhinitis in Children : Diagnosis of AR relles on history and physical exam; antigen testing confirms diagnosis
and directs treatment. SLU Care The Physicians of Saint Louis University. Missouri Medicine. Vol. 105. May/June 2008
36
THERAPY

Pharmacotherapy

Sanford T. Rhinitis in Children : Diagnosis of AR relles on history and physical exam; antigen testing confirms diagnosis
and directs treatment. SLU Care The Physicians of Saint Louis University. Missouri Medicine. Vol. 105. May/June 2008
37
THERAPY
Immunotherapy

KKrouse J., Derebery J., Chadwick S., Managing the allergic patient, Elsevier,
2008
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HIGHLIGHT

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Thank You

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