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Endogenous factors
Regional Sites of Predilection
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What is contact dermatitis?
Chemical
Detergents
Solvents
Wet work
Pot washing
Wet food preparation
Types of Contact Dermatitis
Irritant Contact Dermatitis
An inflammatory reaction in the skin resulting
from exposure to a substance that causes an
eruption in most people who come in contact
with it
Allergic Contact Dermatitis
An acquired delayed sensitivity to various
substances that produce inflammatory
reactions in only those who have been
previously sensitized to the allergen
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Irritant Contact Dermatitis
Pathogenesis
The irritants cause cell damage if applied
for sufficient time and in adequate
concentration. Inflammatory response
occurs because of the inability of the skin
to defend and repair its integrity and
function from penetrating chemicals.
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Irritant Contact Dermatitis
Etiologic Agents
Water, soaps, detergents, bleaches, lye, drain pipe
cleaners, toilet bowl and oven cleansers
Acids and Alkalis
Solvents and Hydrocarbons
Fiberglass, dust, capsaicin, teargas, metal salts
Predisposing Factors
History of atopic dermatitis
Occupational exposure/ Repeated exposure
Low temperature/ Low humidity
Condition of the skin 10
Irritant contact dermatitis
Skin damaged directly by the irritant
soaps, detergents, water, solvents, dry
atmosphere etc
very, very common
atleast 5% of the population suffer from
hand dermatitis
Treat with emollients/moisturisers
Contact Dermatitis
The generic term applied to acute and chronic inflammatory
reactions to substances that come in contact with the skin
Acute dermatitis: pruritus, erythema, and vesiculation
Chronic dermatitis: pruritus, xerosis, lichenification,
hyperkeratosis, and/or fissuring
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Irritant Contact Dermatitis
Irritant contact dermatitis occurs when chemicals or physical agents damage
the surface of the skin faster than the skin is able to repair the damage.
47-year-old housekeeper
was the result of chronic
hand washing combined
with surfactant and other
solvent exposures
Irritant Contact Dermatitis
Acute Irritant Contact Dermatitis
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Irritant Contact Dermatitis
Acute Irritant Contact Dermatitis
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Irritant Contact Dermatitis
Acute Irritant Contact Dermatitis
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Irritant Contact Dermatitis
Acute Irritant Contact Dermatitis
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Irritant Contact Dermatitis
Chronic Irritant Contact Dermatitis
Prolonged and repeated exposures of the skin to
irritants results to a chronic disturbance of the
barrier function, subsequently, elicit a chronic
inflammatory response.
Stinging and itching, pain as fissures develop
LESION
Dryness chapping erythema hyperkeratosis
and scaling fissures and crusting
Lichenification, vesicles, pustules, and erosions
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Irritant Contact Dermatitis
Chronic Irritant Contact
Dermatitis
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Allergic Contact Dermatitis
Acute Allergic Contact Dermatitis
Well-demarcated erythema and edema on
which are superimposed closely spaced,
nonumbilicated vesicles, and/or papules
LESION:
Erythema Papules vesicles erosions
crusts scaling.
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Allergic Contact Dermatitis
Pathogenesis
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Allergic Contact Dermatitis
Acute Allergic Contact Dermatitis
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Allergic Contact Dermatitis
Acute Allergic Contact Dermatitis
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Allergic Contact Dermatitis
Chronic Allergic Contact Dermatitis
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Allergic Contact Dermatitis
Chronic Allergic Contact Dermatitis
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Tests for Sensitivity
Provocative Use Test
Confirms a positive closed patch test reaction
to ingredients of a substance; to test products
that are made to stay on the skin once applied
Photopatch Test
To evaluate for contact photoallergy to such
substances as sulfonamides, phenothiazines,
PABA, oxybenzone, musk ambrette
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Tests for Sensitivity
PATCH TEST
To detect hypersensitivity to a substance that is in
contact with skin so that the allergen may be
determined and corrective measures taken
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How to prevent contact dermatitis?
Avoid contact
No contact No dermatitis
Make people aware of dermatitis
and its causes
Where possible
Use automation (eg. mixing or peeling)
Handle food with tools (eg tongs)
Buy in ready prepared ingredients
Use a dishwasher
Use tools for cleaning and pot
washing
Management for Contact Dermatitis
Prevention
Avoid exposure to potential allergen
Avoid repeated and prolonged exposure to
irritants
Wear protective clothing
Check skin reactions to cosmetics before
applying
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Protect the skin
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Allergic Contact Dermatitis
Chronic Allergic Contact Dermatitis
Plaques of lichenification (thickening of the
epidermis with deepening of the skin lines in
parallel or rhomboidal pattern), scaling with
satellite, small, firm, rounded or flat-topped
papules, excoriations, erythema, and
pigmentation
LESION
Papules scaling lichenification excoriations
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How to prevent contact dermatitis?
Avoid contact
No contact No dermatitis
Make people aware of dermatitis
and its causes
Where possible
Use automation (eg. mixing or peeling)
Handle food with tools (eg tongs)
Buy in ready prepared ingredients
Use a dishwasher
Use tools for cleaning and pot
washing
Protect the skin
Prevention
Avoid exposure to potential allergen
Avoid repeated and prolonged exposure to
irritants
Wear protective clothing
Check skin reactions to cosmetics before
applying
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