DEFINITION

Leukemia is a cancer of blood. It is a group of

malignant disorders affecting the blood and tissue
forming the blood such as:
Bone marrow
Lymph system
Spleen
Leukemic cells replace white blood cells and
makes the body very weaker and vulnerable to
any infection

Leukemia may affect females and males of all

age groups
TYPES OF LEUKEMIA

Acute
Acute Lymphoblastic Leukemia(ALL)
Acute Myeloid Leukemia(AML)

Chronic
Chronic Myeloid Leukemia(CML)
Chronic Lymphocytic Leukemia(CLL)
DIFFERENCES BETWEEN ACUTE
AND CHRONIC LEUKEMIA
ACUTE
Progress rapidly
Severely ill
Heals without complication
Common in younger age
groups
Need immediate treatment
It is prominent
Prognosis is predictable
Normal growth factor levels
Normal level of inflammatory
cytokines
CHRONIC
Progress slowly
Can be asymptomatic
Complication arises
Common in older age groups
Treatment can be delayed
It is mild
Prognosis is unpredictable
Lower growth factor levels
Increased level of pro
inflammatory cytokines
PATHOPHYSIOLOGY
 ETIOLOGY
Heredity
Environmental factors
Infections
Consumption of alcohol
and drugs
Smoking
Radiation exposure
Association with diseases
of immunity
DIAGNOSIS
Blood test
Bone marrow test
Biopsy
Physical test
Blood cell examination
Cytogenetic
 TREATMENTS
Chemotherapy
Biological Therapy
Targeted Therapy
Radiation Therapy
Stem Cell Therapy
Watchful Waiting
Bone Marrow Transplantation
 GRAPH REPRESENTING
PERCENTAGE OF LEUKEMIA
PATIENTS BASED ON AGE