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Chapter 13
The Endocrine System
Principles of Endocrinology
Homeostasis
Growth and development
Reproduction
Energy production, storage, and use
Behavior
The Human
Endocrine System
• Target cells contain receptors for
specific hormones.
Dwarfism Giantism
Thyroid Stimulating
Hormone (TSH)
•Main function is
stimulating the
breakdown of glucose.
Adrenocorticotropic Hormone
(ACTH)
Prolactin Secretion
The posterior pituitary
secretes two
hormones.
1. Antidiuretic
hormone increases
the water
absorption in the
kidney.
– Oxytocin facilitates
birth and stimulates
milk let-down.
The Thyroid Gland
Thyroxine (T4)
Triiodothyronine
Calcitonin
• Thyroxine and triiodothyronine accelerate the
breakdown of glucose and stimulate growth and
development.
• Glucagon increases
blood levels of glucose,
thus opposing the
actions of insulin.
• Diabetes mellitus is a disease resulting
from an insulin deficiency or a decrease
in tissue sensitivity to insulin.
– Diabetes has two principal forms:
• Type I, or early-onset diabetes, may be
caused by an autoimmune reaction that
destroys the beta cells of the pancreas. It can
be treated by insulin injections.
• Type II, or late-onset diabetes, results from a
reduction in the number of insulin receptors on
target cells. It is caused by obesity and genetic
factors and can often be treated successfully by
dietary management.
The Adrenal Glands