Escolar Documentos
Profissional Documentos
Cultura Documentos
• GROUND SUBSTANCE
– Glycosaminoglycans
(chondroitin sulfates, keratin
sulfate, hyaluronic acid)
– Proteoglycans: GAGs + core
protein
– Water
• Basophilic
• Territorial matrix - high [ ] of
sulfated proteoglycans
CARTILAGE GROWTH
• Appositional
– Increasing in WIDTH;
chondroblasts deposit
matrix on surface of
pre-existing cartilage
• Interstitial
– Increasing in
LENGTH;
chondrocytes divide
and secrete matrix
from w/in lacunae
TYPES OF CARTILAGE
• HYALINE
• ELASTIC
• FIBROUS
HYALINE CARTILAGE
• FUNCTION
– Support tissue and organs
– Model for bone
development
• MATRIX
– Type II collagen (thin
fibrils)
– Chondroitin sulfate, keratin
sulfate, hyaluronic acid
– Water
• LOCATION
– Tracheal rings, nasal
septum, larynx, articular
surfaces of joints
ELASTIC CARTILAGE
• FUNCTION
– Support with flexibility
• MATRIX
– Normal components of hyaline
matrix plus ELASTIC fibers
• LOCATION
– External ear, external auditory
canal, epiglottis
• STAINS perichondrium
– Elastic fibers stain BLACK
with Weigert stain
FIBROCARTILAGE
• FUNCTION
– Support with great
tensile strength
• MATRIX
– Type I collagen -
Oriented parallel to
stress plane
• LOCATION
– Intervertebral disks,
pubic symphysis
FIBROCARTILAGE
• Chondrocytes align
between collagen fibers
• Collagen fibers lie
parallel to lines of stress
How many types of cartilage do
you see?
SYNOVIAL (DIARTHRODIAL)
JOINTS
JOINT DEFINITIONS
• SYNOVIAL CAVITY
– Fluid filled space b/t 2 bones
• SYNOVIAL FLUID
– Water and GAGs; provides
nutrients for cartilage
• SYNOVIAL MEMBRANE
– Continuous with the
perichondrium
SYNOVIAL “MEMBRANE”
Not a true membrane -
Why?
• Specialized secretory CT
• Loose (areolar) CT
• Formed by layers of
collagen and fibroblasts
• Highly vascular
• No perichondrium
• Joint capsule
composed of DIACT
C
B
C
Questions 2 and 3:
4. What cartilage
nourishing
tissue is
missing at the
interface
shown?
a. Synovial fluid
b. Perichondrium
c. Synovial
membrane
d. Chondroblasts