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Prevent Recurrence. Provide Reassurance.

www.techtronic.com
12/3/2013 Techtronic Medical Devices 1
Breast Cancer
❏ Breast Cancer: 39,500 deaths/year
❏ 12% risks of breast cancer diagnosis for a woman during her life
❏ Surgery nearly always necessary (30% mastectomy, 70% lumpectomy)
❏ Mastectomy requires reconstruction; lumpectomy often requires second surgery
because of incomplete removal

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Breast Cancer Relapse
❏ 1 in 5 women see a recurrence of cancer within 5 years.

❏ Recurrence of tumor may lead to more surgeries

and significant health problems.

➢ Depends on the woman’s initial treatment.

➢ Sophisticated and very expensive method.

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Current Treatments/Drugs

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Side Effects/ Risks

..and of course, very expensive to go for the second time.


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Novel approach
❏ Based on research from Brown
university

❏ Nanoscale - Bed of Nails

❏ Prevents cancerous cells from


growing

❏ Doesn’t impede growth of healthy


breast tissue

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Implants details
❏ Protected by U.S. Patent #6,991,652.

❏ FDA approved polymer used to build the


nanoscale surface

❏ Therapy based on physical nature of device rather


than drug.

❏ Class 3 Medical Device (requires FDA and CE


clearance).

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Why choose our implants ?
❏ High-tech scaffolds are an area of ongoing research – the time is now!

❏ The preventative nature of the implants makes it attractive for customers and will
help us capture a huge market share!
Others
❏ Reduce the cost of treatment. competitors
Prevent cancer recurrence

Reduced side effects

Help breast reconstruction

Help breast recovery


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Why choose our implants ?
❏ High-tech scaffolds are an area of ongoing research – the time is now!

❏ The preventative nature of the implants makes it attractive for customers and will
help us capture a huge market share!
Others
❏ Reduce the cost of treatment. competitors
Prevent cancer recurrence

We save lives! Reduced side effects

Help breast reconstruction

Help breast recovery


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Market
In 2012, 264,000 implants were use for
reconstruction.
-> Selling price : $4,000. Evolution of breast cancer
100
-> Manufacturing cost : $1500
80

Rate per 100,000


 Potential market : 1Billion$
60
 Margins : 62.5% 40

20

0
1975 1980 1985 1990 1995 2000 2005 2010 2015
Year

Age 50 + All ages

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Strategy
❏ Certification in Europe first.

❏ EU regulatory process
Easier
Faster
More chances of success

❏ Access to the 2nd medical device market


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Strategy
Once we have the Mark

Can start to sell in Europe

Value added milestone Increase our valuation

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Strategy
Clinical trials in the US

FDA approval

Value added milestone Increase our valuation (again)

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Financial plan overview
Seed Series A Series B Series C
2014
2015 2016 2017 2018 2019 2020 2021
Q1 Q2 Q3 Q4
European patent application
Prototype production
Pre-clinical trials
Clinical trials outside of the US
CE certification
FDA approval
Clinical trials inside the US
35
Millions

30

25

20

15

10

0
Q1 Q2 Q3 Q4 2015 2016 2017 2018 2019 2020 2021

Revenue Expenses Cash flow


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Challenges to increase our value !

Market to the US

FDA Approval

Market to Europe first

Physician and patient adoption


Health insurance reimbursement
CE Mark
Clinical trial

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The team
Senior staff : R&D Team :

❏ Dr. Karen BURG ❏ World class multidisciplinary research team coming


from leading research institutes
Inventor of the technology
Chief Technical Officer
Advisory Board :

❏ Dr. Jiss John


❏ Alexandre Guelaud
Oncologist, Yale Medical School
Company's business and corporate development

❏ Dr. Vedanth Pullagurla ❏ Dr. Jessy Corbier


VP of Research and Development Senior advisor

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Questions

Objective Techtronic Medical Devices develop a breast implant able to highly


reduce the risk of breast cancer recurrence
Business plan • Prototype manufacturing
scope • Clinical trial
• CE mark
• FDA approval
What’s in it • Invest in a disruptive technology able to capture a huge market share
for you • Help to save lives
• Continued involvement with the company

Email : contact@techtronic.com

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