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Product Dose Mode of Administration

PO administered approximately 12
Dexamethasone 20 mg and 6 hours before paclitaxel
injection

Diphenhydramine (or its IV 30 to 60 minutes prior to

50 mg paclitaxel injection
equivalent)

Cimetidine/Ranitidine
300 mg / 50 IV 30 to 60 minutes before
mg paclitaxel injection
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Preparation For Intravenous
XELPAC
Administration
Paclitaxel Injection must be diluted prior to infusion

Paclitaxel Injection should be diluted in 0.9% NS, USP; 5% Dextrose Injection, USP or
5% Dextrose in Ringer's Injection to a final concentration of 0.3 to 1.2 mg/mL

The solutions are physically and chemically stable for up to 27 hours at ambient
temperature (approximately 25° C) and room lighting conditions.

Upon preparation, solutions may show haziness, which is attributed to the formulation
vehicle. No significant losses in potency have been noted following simulated delivery of
the solution through IV tubing containing an in-line (0.22 micron) filter.
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In general, Paclitaxel is administered as 3 hour infusion for 3

weeks/Weekly
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Features XELPAC

PVC & DEHP Free

• Plasticizer (Carcinogenic)
Features XELPAC

0.22 micron filter

•Removes Micro
Particles/Residues
Features XELPAC

Non-Toxic

•Inert nature diminishes

chemical reaction
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Pyrogen Free

•Anti Fever
•Anti Bacterial
Features XELPAC

EO Sterile

•Ensures Safety
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Automatic Air Venting

•Minimizes Air Lock during

infusion
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PLATINEX
CARBOPLAT
PEMETREX
XELPAC
Benefits XELPAC

Ensures Safe
Distribution & Protects from
Protects vial up to a
Handling of Moisture, Heat & Sun
30 feet drop
chemotherapeutic Light
drugs

Avoids dermal Ensures both

Open top allows
exposure during personal &
easy needle
preparation & environmental
insertion
administration safety
Indications XELPAC

Non-Small Gastric-
Ovarian Cell Lung Esophagus
Cancer Cancer Cancer

Breast Head- Cervical

Cancer Neck Cancer
Cancer
Thank
You