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Endothelial
cell
Diameter 4-9
um
Basement membrane
dr abdelaziz Hussein, Mansoura Faculty
of Medicine
dr abdelaziz Hussein, Mansoura Faculty
of Medicine
•Blood in capillary is not continuous, but it is
intermittent
Cause:
• It is due to intermittent contraction of the
metarterioles and precapillary sphincters (
Vasomotion)
• There is a cycle of constriction and relaxation for 5 to
10 times per min, so only about 10-20% of the
capillaries are opened at a time.
dr abdelaziz Hussein, Mansoura Faculty
of Medicine
Regulation of capillary Vasomotion:
• Vasomotion is controlled by the O2 concentration in
the tissues.
• When the O2 concentration is very low→ the
intermittent periods of blood flow occur more often
and the duration of each period of flow lasts for a long
time, thereby allowing the blood to carry ↑ed
quantities of O2 to the tissues.
Low O2 tension
High O2 tension
Arteriolar ↓ capillary
Constriction B.P.
dr abdelaziz Hussein, Mansoura Faculty
of Medicine
↑ capillary ↑ venous
B.P. B.P.
↓ capillary ↓ Venous
B.P. B.P.
T=Pxr