Escolar Documentos
Profissional Documentos
Cultura Documentos
elbow partner:
What physical traits did you inherit and from
whom?
What traits can be inherited?
Definition – diagram of family relationships that
use symbols to represent people and lines to
represent genetic relationships. (genotypes &
phenotypes)
Example :
h Hh (Huntington’s) hh
h Hh (Huntington’s) hh
Parent 1 = Normal
h h
Parent 2 = Normal
h hh hh
h hh hh
H Hh (Huntington’s) Hh (Huntington’s)
h Hh (Huntington’s) Hh (Huntington’s)
Partner 1, tell Partner 2 some of the
characteristics of an Autosomal Dominant
disorder.
Males & females are equally likely to have the
trait
Trait often skips generations
Only homozygous individuals have the trait
Parents who have children with the trait must
be heterozygous
If a parent has the trait, their offspring who
do not have it are heterozygous carriers for
the trait
Parent 1 = Carrier
F f
Parent 2 = Normal
F FF Ff (Carrier)
F FF Ff (Carrier)
Parent 1 = Carrier
F f
Parent 2 = Carrier
F FF Ff (Carrier)
Parent 1 = Cystic
Fibrosis f f
Parent 2 = Carrier
F Ff (Carrier) Ff (Carrier)
Mom = Normal
X X
Dad = Normal
X XX XX
Y XY XY
Partner 1, tell Partner 2 explain some of the
characteristics of an X-link Dominant
disorder.
Trait is coded for on the X chromosome
Trait more common in males than females
If a male has the trait, all of his daughters will be
heterozygous carriers
Sons of female carriers have a 50% chance of
having the trait
Males can not pass the trait to their sons
A male inherits the trait from his mother who is a
carrier
Daughters of female carriers have a 50% chance
of being a carrier
Mom=Carrier
X0 X
Dad = Normal
X X0X (Carrier) XX
Y X0Y (DMD) XY
Mom = Normal
X X
Dad = Normal
X XX XX
Y XY XY
Partner 2, tell Partner 1 some characteristics
of an X-link Recessive disorder.
With a partner, determine whether the
pedigree is an example of a AR, AD, XR, or
XD.
Write the answers in on your graphic
organizer.
Does alkaptonuria
appear to be caused by a
dominant or recessive
allele?
What are the genotypes
of the following
individuals?
◦ George
◦ Carla
◦ Tom
◦ Arlene
◦ Michael
Work through question 18 with your elbow
partner. Be prepared to share your answers
with the class.
Bob = Aa
Barb = aa
Charlie = Aa
Ethan = aa
Candice = Aa
Isabelle = aa
Candice = A a
Huntington’s
50% Chance
Parker = Normal
a Aa aa
a Aa aa
Answer the questions for question 19
individually. Be prepared to share out to the
class.
Edward VII = XY
Alice = XhX
Queen Victoria = XhX
Leopold = XhY
Beatrice = XhX
Henry of Prussia = XY
Leopold = Xh Y
Hemophilia 0% Chance of
Wife = Non-Carrier Hemophilia
100% Chance o
X XhX XY
being a carrier
X XhX XY
Working with a partner, read through the case
study of the Grouch family.
Answer 20 a and 20 b with your partner.
Hemoglobin is the iron-
containing oxygen-
transport protein in red
blood cells.
Methemoglobin is a form
of a hemoglobin that
can’t bind oxygen. When
excess methemoglobin is
present, the blood
becomes abnormally
dark and can cause some
skin discoloration.
Read paragraphs 1-20. Stop and write a
short summary.
Read paragraphs 21-40. Stop and write a
short summary.
Read paragraphs 41-58. Stop and write a
short summary.
Answer the following questions about your reading
with your partner on your graphic organizer:
What is the name of the disorder described in the
article?
Describe the group of people effected by this
disorder.
Is the disorder autosomal or x-linked?
Is the disorder recessive or dominant?
Where did this population reside?
Describe the symptoms of the disorder?
How was this disorder inherited?
Why was the disorder isolated to this population?
Draw a pedigree chart of your family
including yourself, your parents and siblings,
your parents.
◦ Identify and color the symbols accordingly for one
of the following traits:
Right or left handed
Freckles
Free/attached earlobes
Widows peak
Tongue roller/non-roller