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CH 19 (pp 731-747)
March 19, 2015
http://www.science-groove.org/Now/Oxidative.html
Case Study
Overall:
2 Cr2O72- + 3 C2H5OH + 16 H+ -->
4 Cr3+ + 3 CH3COOH + 11 H2O
Higher tendency
Half Reactions
for reduction
In general,
Reduced Oxidized
Lower tendency
for reduction
Half Reactions
In general,
Reduced Oxidized
DG’ = -nF’cell
In-Class Problem
Electron
transport chain
sets up an H+
gradient (proton
motive force).
Energy of the
pmf is harnessed
to make ATP.
Fig 19-2
Mitochondrion
Mobile
electron
carrier within
the bilayer
1- or 2-
electron Fig 19-3
acceptor
ETC carriers: FMN
Prosthetic group
of ETC protein
(complex I)
1- or 2-electron
acceptor
ETC carriers: Cytochromes
Heme proteins
Cytochrome c is a
soluble peripheral
protein
ETC carriers: Iron-sulfur proteins
Fig 19-5
ETC carriers: Copper centers
~Fig 19-16
Complex I
Alternate Entries
Fig 19-8
Alternate Entries
Complex II
(aka succinate
dehydrogenase)
Alternate Entries
Fig 19-8
Alternate Entries
Fig 19-8
Electron Transport Chain
Complex III
Complex III
Fig 19-11
Electron Transport Chain
Complex IV
Fig 19-14
Complex IV
Electron Transport Chain
Succinate
dehydrogenase
Succinate
dehydrogenase
4 H+ in 4 H+ out
2 H+ in 2 H+ out
Flow direction
Flow direction
Inhibitors of electron transport
Fig 19-6
Case Study
Inhibitor a b c d
1 + + - +
2 - - - +
3 + - - +
Substrate added
Substrate
consumed
Data can be
reported as O2
concentration
or O2
consumption.
Coupling of electron transport
and ATP synthesis
Fig 19-20
Coupling of electron transport
and ATP synthesis
Fig 19-20