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Journal Reading

The importance of blood lipids


in the association between BMI
and blood pressure among
Chinese overweight and obese
children
British Journal Of Nutrition · May 2016

Idham Muhammad
Dept./SMF Ilmu Kesehatan Anak
FK UNPAD/RSHS
PENDAHULUAN
Peneliti menghipotesis 
Asosiasi obesitas dan hipertensi sebagian dimediasi oleh lipid
darah abnormal

Pada penelitian ini menilai :


Asosiasi langsung BMI dan Tekanan darah
Peran lipid darah pada asosiasi BMI dan tekanan
darah
Hasil dipresentasikan berdasarkan jenis kelamin dan
potential covariat terkontrol
METODE
Alur Analisis
HASIL
Karakteristik Umum

Signifikan : TB, BB, BMI, SBP


Asosiasi BMI, Kadar Lipid, Tekanan Darah Sistolik
Asosiasi BMI, Kadar Lipid, Tekanan Darah Diastolik
Terdapat Asosiasi
langsung Tekanan
darah dan Profil Lipid
DISKUSI
Data pada anak
masih sedikit

Perbedaan jenis kelamin berkaitan dengan kadar lipid dan tekanan darah

Penelitian sebelumnya  Trigliserida berkaitan dengan


HIPERTENSI

Penelitian ini menunjukkan


terdapat asosiasi signifikan TC, TAG, LDL pada Tekanan
darah Sistolik/Diastolik
(setelah penyesuaian BMI dan usia)
Pengaruh Jenis Kelamin
KELEBIHAN &
KEKURANGAN
KESIMPULAN
CRITICAL
APPRAISAL

2
1
◆ METHOD : CROSS SECTIONAL
◆ Level of evidence : IV B
INTRODUCTION YES NO DON’T
KNOW/COMMENT
Were the aims/objectives of the study clear? Y
METHODS
Was the study design appropriate for the stated aim(s)? Y
Was the sample size justified? Y
Was the target/reference population clearly defined? (Is it clear who the Y
research was about?)
Was the sample frame taken from an appropriate population base so that Y
it closely represented the target/reference population under investigation?
Was the selection process likely to select subjects/participants that were Y
representative of the target/reference population under investigation?
Were measures undertaken to address and categorise non-responders? DK
Were the risk factor and outcome variables measured appropriate to the Y
aims of the study?
Were the risk factor and outcome variables measured correctly using DK
instruments/measurements that had been trialled, piloted or published
previously?
Is it clear what was used to determined statistical significance and/or Y
precision estimates? (e.g. p-values, confidence intervals)
Were the methods (including statistical methods) sufficiently described to Y
enable them to be repeated?

Downes MJ, Brennan ML, Williams HC, Dean RS. 2016 https://bmjopen.bmj.com/content/6/12/e011458
RESULTS YES NO DON’T
KNOW/COMMENT
Were the basic data adequately described? Y
Does the response rate raise concerns about non-response bias? Y
If appropriate, was information about non-responders described? Y
Were the results internally consistent? Y
Were the results presented for all the analyses described in the methods? Y
DISCUSSION
Were the authors' discussions and conclusions justified by the results? Y
Were the limitations of the study discussed? Y
OTHER
Were there any funding sources or conflicts of interest that may affect the N
authors’ interpretation of the results?
Was ethical approval or consent of participants attained? Y

Downes MJ, Brennan ML, Williams HC, Dean RS. 2016 https://bmjopen.bmj.com/content/6/12/e011458
Applicability

Can the results be applied to your organization?

YES.
With the modified setting.
TERIMA
KASIH
Subtitle

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