pharmacodynamics of antibiotics To know the concepts about drug resistance, hypersensitivity and superinfection To describe the most common uses of antibiotics To summarize the importance of health teaching with each antibiotics Facts • are medications that destroy or slow down the growth of bacteria. • Alexander Fleming discovered Pennicillin, the first natural antibiotic, in 1928. • Antibiotics cannot fight viral infections. • Fleming predicted the rise of antibiotic resistance. • Antibiotics either kill or slow the growth of bacteria. • Side effects can include diarrhea, GI upset, and nausea. Infection Not all Microorganism are Harmful Pathogens Produce Infection and disease Immunity External Immune System Internal Immune System Immunization ADMINISTRATION CONSIDERATION 1. Condition of the patients defense system 2. Type of infection and its cause Blue staining microbes – Gram positive Red staining microbes – Gram negative 3. Type of drug and its effects Broad spectrum antibiotics Narrow spectrum antibiotics Hypersensitity - exaggerated immune response Superinfection – secondary infection, another microbial agent penicillin Largest group of antibiotics, most effective and least toxic Natural penicilllins are made from mold that grows from bread and fruit ex. Penicillin G potassium & Penicillin V for strepthroat and syphillis ex. Amoxicillin – may be given preventively for Major Types of Antibiotics Penicillins and Penicillin resistant Antibiotics - Arizza Cephalophosporins - Tonee Tetracylines - Yomi Aminoglycosides - Anne Sulfonamides - Jeff Quilonones - Michael Carbapenems - Maynard Other Antibiotics: Macrolides - Ira Lyncosamindes - Princess Lipoglycopeptides – Rinz Monobactam - Aina Ketolides - Louise