Escolar Documentos
Profissional Documentos
Cultura Documentos
• 1984 : 15.5%
• 1985 : 14.9%
• 1986 : 16%
• 1987 : 30.9% ( 파주 , 여주 )
Microbiology and distribution
• Mainly serogroup ictohemorrhagiae an
d canicola
• 전북 , 서울 , 강원 , 충북 , 충남
• CH-48 : 춘천지방 , 혈청형 미상
• Serovar : mainly lai
Pathogenesis
• Entry sites : skin wounds or abrasions in hand and
feet and mucous membranes, conjunctiva, nasal, o
ral
• Bacteremia involving the entire body including ey
e, CSF
• Systemic effect and vasculitis due to endotoxin (hy
aluronidase) and burrowing motility
• Hemorrhagic necrosis esp. in liver, lung, and kidn
eys jaundice, ARF, hemorrhages
Clinical types
Types 1986 1987
Pneumonitis 33% 57.7%
Rash type 17%
Weil’s disease 15%
Renal failure 13% 53.8%
“Flue-like” 15% 13.5%
Acute Hepatitis 8%
Combination 86.5%
Phase I (Septicemic)