DR.

MUHAMMAD IJAZ
Assistant Professor
Clinical Medicine & Surgery
• Foot and Mouth Disease
• Haemorrhagic Septicemia
• Clostridium
• Brucella
• Bovine Viral diarrhea
• Bovine Rhinotracheitis
• Bovine Respiratory Syncytial Virus
• Parainfluenza
• Leptospira
• Rabies
• Black Leg
 Vaccination Schedule for Commercial Dairy Farming

Age of Animals Name of Vaccine Time of Vaccination Time of Booster Need

Pre-Calving E. coli (k-199) + Priming 6 weeks before

3 weeks before calving Optional
vaccination Rota+ Corona Virus vaccine calving

Booster 3 week later

Clostridial Combo vaccine
1-4 weeks
like (Covexine-10, Toxipra)
1-3 months FMD (O, A, Asia-1) + HS
Triangle-10 vaccine or
4 month
Elite-9 vaccine
Any time but Preferably in
Repeat every year till age Optional
February & September
of 3years
Booster 3 week later
-do- Required
Repeat every year
Booster 3 week later
-do- Required
Repeat every year

Bovi-shot vaccine (RB-51)

4-5 month -do- ? Once a life Required
against Brucella abortus

4-5 month Bovine Ephemeral Fever Repeat every year Optional

04 Years Black quarters + *Anthrax Repeat every year Required

* in endemic areas
 Brucella Vaccine
Company Trade Availability
Name Name in Pakistan Dosage Route Price (Rs.)
CAVAC BoviShot® S/C in neck 6000/10ml
(S. Korea) Brucel Yes 1.0 ml region vial

RB 51 strain
 Bovine Ephemeral Fever
Company Availability
Name Trade Name in Pakistan Dosage Route Price (Rs.)
CAVAC BoviShot ®
(S. Korea) Ephemer Yes 2.0 ml S/C 2000/5ml vial

Attenuated Bovine
Ephemeral fever
virus culture fluid
 Black Quarter Vaccine
Company Availability
Name Trade Name in Pakistan Dosage Route Price
VRI
(Pakistan) Black Quarter® Yes 5ml S/C -
Pfizer £13.49/50ml
(USA) Black Leg®Vaccine Yes 2ml S/C vial

Composition:
Clostridium chauvoei
 Bar-Vac CD Vaccine

Company Name Trade Availability in Dosage Route Price($)

Name Pakistan
Boehringer Ingelheim Bar-Vac® No 5ml S/C 21.19/250 ml
(USA) CD

Clostridium perfringens( Type C & D)

Clostridium tetani
 TOXIPRA

Company Availability in
Name Trade Name Pakistan Dosage Route Price (Rs. )

HIPRA TOXIPRA ® 4.0 ml/Large 8500/250ml

(Spain) PLUS Yes 2.0ml/sucklers S/C vial

HIPRA TOXIPRA ® 4.0ml/Large 8300/250ml

(Spain) S7 Yes 2.0ml/sucklers S/C vial
 •Clostridium perfringens (B,C,D)
•Clostridium perfringens (B,C,D)
•Cl. septicum
•Cl. septicum
•Cl.novyi
•Cl. novyi
•Cl.chauvoei
•Cl. chauvoei
•Cl.sordelli
•Cl. sordelli
•Cl.tetani
 COVEXIN 10

Company Availability in
Name Trade Name Pakistan Dosage Route Price (€)
CAVAC
(Ireland) Covexin® 10 No 2.0 ml S/C 66.0 /100ml vial

•Clostridium perfringens(A, B, C, D)
•Cl. chauvoei
•Cl. novyi
•Cl. septicum
•Cl. tetani
•Cl. sordellii
•Cl. haemolyticum
 Foot & Mouth Disease Vaccine
Company Trade Name Availability Dosage Route Price
Name in Pakistan (Rs./vial )
FAO Foot & Mouth Yes 2.0ml S/C -
Disease Vaccine®

Merial Aftovaxpur® Yes 2.0 ml S/C 4600/50ml

(France) 2000/20ml
FGBI Foot & Mouth Yes 2.0ml S/C 6000/50ml
(Russia) Disease Vaccine®
VRI FMD® Vaccine Yes 5.0 ml S/C -
(Pakistan)
Intervet Decivac® Yes 2.0ml S/C 250/2ml
(S. Africa)
Foot & Mouth Disease Aftovaxpur FMD Vaccine Decivac Vaccine
Vaccine A, O Asia I types A, O Asia I types
A,O Asia I
 Hemorrhagic Septicemia
Company Trade Name Availability Dosage Route Price
Name in Pakistan (Rs./vial)
VRI HS Vaccine® Yes 2ml I/M -
(Pakistan)
Sana Lab. Pamusan®HS Yes 5ml/300kg S/C 180/25ml
(Pakistan) Vaccine
Syva Neo bacterina® Yes 2 ml S/C 2300/100 ml
(Spain)
Intervac INTERVAC®HS Yes 3ml S/C or 145/30ml
(Pakistan) I/M
NIAB HS® vaccine Yes 5 ml IM 10/5ml
(Pakistan)
 Pasteurella multocida

Pasteurella
multocida Pasteurella
haemolytica biotypes
A1, A2 and T10
Pasteurella multocida

NIAB HS- Vaccine

VRI HS- Vaccine
 HIPRABOVIS

Company Availability
Name Trade Name in Pakistan Dosage Route Price (£)

HIPRA 62.5/25
(Spain) HIPRABOVIS®4 Yes 3ml I/M or S/C Doses

•Infectious bovine rhinotracheitis (IBR)

•Bovine virus diarrhea (BVD)
•Parainfluenza 3 (PI3)
•Bovine respiratory syncytial virus (BRSV)
 Elite 9
Company Trade Availability
Name Name in Pakistan Dosage Route Price (Rs./vial)
Boehringer
Ingelheim
(USA) Elite® 9 No 5ml I/M or S/C 17000/ 250 ml

•Infectious bovine rhinotracheitis (IBR)

•Bovine virus diarrhea (BVD types 1)
•Parainfluenza 3 (PI3)
•Bovine respiratory syncytial virus (BRSV)
•Leptospira pomona
•L. hardjo
•L. grippotyphosa
•L. canicola
•L. icterohaemorrhagiae
 Triangle 9
Company
Name Trade Availability in
Name Pakistan Dosage Route Price($)
Boehringer
Ingelheim 20.0/
(USA) Triangle® 9 No 5ml I/M or S/C 50ml

•Infectious bovine rhinotracheitis (IBR)

•Bovine virus diarrhea (BVD types 1)
•Parainfluenza 3 (PI3)
•Bovine respiratory syncytial virus (BRSV)
•Leptospira pomona
•L. hardjo
•L. grippotyphosa
•L. canicola
•L. icterohaemorrhagiae
 Triangle 10
Company Availability
Name Trade Name in Pakistan Dosage Route Price ($/vial)
Boehringer
Ingelheim $ 20/ 50ml
(USA) Triangle® 10 No 5ml I/M or S/C $ 92 / 250ml

•Infectious bovine rhinotracheitis (IBR)

•Bovine viral diarrhea (BVD types 1 & 2)
•Parainfluenza 3 (PI3)
•Bovine respiratory syncytial virus (BRSV)
•Leptospira pomona
•L. hardjo
•L. grippotyphosa
•L. canicola
•L. icterohaemorrhagiae
 Bovine Rota Corona Vaccine
Company Availability in
Name Trade Name Pakistan Dosage Route Price($)
Zoetis Bovine Rota No 3 mL in Orally in 94.89 for 25
(USA) corona virus® calves calves vials(3 mL
vaccine 3mL in IM in each)
pregnant pregnant
bovines bovines

Composition:
•Rotavirus and Corona virus
 Bovine Rota Corona Vaccine

Company Availability
Name Trade Name in Pakistan Dosage Route Price (£/vial)
Intervet I/M during
(S.Africa) Rotavec®Corona No 2ml pregnancy 196.60/40ml

Composition:
•Bovine RotaVirus
•E.Coli F5 (K99)
•Bovine CoronaVirus
 Rabies
Company Availability in
Name Trade Name Pakistan Dosage Route Price (Rs.)
Merial
(France) Rabisin® Yes 1ml S/C 180/ml
Dyntec
(Denmark) Canvac® R Yes 1 ml S/C 137/ml
Bioveta Biocan® R Yes 1 ml S/C 125/ml

Composition:
Inactivated Rabies Antigen