Atorvastatin (Lipitor) is a cholesterol-lowering medication that blocks the production of

cholesterol in the body.

Atorvastatin reduces low-density lipoprotein (LDL) cholesterol and total cholesterol in the blood.
Lowering your cholesterol can help prevent heart disease and hardening of the arteries, conditions
that can lead to heart attack, stroke, and vascular disease.

Atorvastatin is used to treat high cholesterol. Atorvastatin is also used to lower the risk of
stroke, heart attack, or other heart complications in people with coronary heart disease or type 2
diabetes.

Atorvastatin may be used in combination with bile acid resins. It is not recommended to combine
statin treatment with fibrates because of the increaesed risk of myopathy related adverse
reactions.

Initial dose: 10 to 80 mg orally once a day (usual adult dose for prevention of cardiovascular
disease)

Initial dose: 10,20 or 40 mg orally once a day (usual adult dose for hyperlipidemia)

Initial dose: 10 mg per day (for 10 to 17 years old; usual pediatric dose for heterozygous familial
hypercholesterolemia)
Adverse reactions have usually been mild and transient. In controlled clinical studies of 2502 patients, <2% patients were discontinued to
adverse experiences attributable to atorvastatin. The most frequent adverse events thought to be related to atorvastatin were
constipation, flatulence, dyspepsia, and abdominal pain

The following are some of the adverse reactions of atorvastatin:

Body as whole: Infection, headache, accidental injury, flu syndrome, abdominal pain, back pain, allergic reaction, and asthenia

Digestive system: constipation, diarrhea, dyspepsia, and flatulence

Respiratory system: sinusitis, and pharyngitis

Skin and appendages: rash

Muscoloskeletal system: arthritis, leg cramps, and bursitis

Urogenital system: UTI, hematuria, albuminuria, kidney failure

Nervous system: insomnia, dizziness, abnormal dreams, depression

Cardiovascular system: palpitation, hypertension

Prepared by:

Angela Marie M. Baroña

2APH