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¢ßa
exerts
point-to-point control through
nerves, similar to sending
messages by conventional
telephone. Nervous control is
electrical in nature and fast.
R
¢ßa
broadcasts its
hormonal messages to essentially all
cells by secretion into blood and
extracellular fluid. Like a radio
broadcast, it requires a receiver to get
the message - in the case of endocrine
messages, cells must bear a
for the hormone being broadcast in
order to respond.
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[ 1,25-dihydroxy Vitamin D3 is also derived
from cholesterol and is lipid soluble
[ Not really a ³vitamin´ as it can be
synthesized de novo
[ Acts as a true hormone
#ëV. 00
V
¢ a
a
aa Stores of
arachadonic acid are present in membrane lipids
and released through the action of various lipases.
The specific eicosanoids synthesized by a cell are
dictated by the battery of processing enzymes
expressed in that cell.
¢ These hormones are rapidly inactivated by being
metabolized, and are typically active for only a
few seconds.
#ëV. 00
V
¢ |
are a large group of molecules
derived from polyunsaturated fatty acids.
¢ The principal groups of hormones of this
class are prostaglandins, prostacyclins,
leukotrienes and thromboxanes.
Õ
[ Sensing and signalingÚ a biological need is sensed,
the endocrine system sends out a signal to a target
cell whose action addresses the biological need.
Key features of this stimulus response system areÚ
receipt of stimulus
synthesis and secretion of hormone
delivery of hormone to target cell
evoking target cell response
degradation of hormone
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