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G.Grazziotin
produo:
glndulas endcrinas ou tecido neurossecretor
Hormnios
atuao:
nas clulas-alvo (com receptor)
degradao: transporte:
no sangue: livres ou ligados s protenas plasmticas pelo fgado (fezes) e excreo renal
Mecanismos de ao:
Reproduo
Hormnios
ativao direta do gene
H. derivados da Tirosina
two polypeptide chains: 21aa, 30aa
http://cwx.prenhall.com/bookbind/pubbooks/mcmurrygob/medialib/media_portfolio/20.html
http://www.people.virginia.edu/~rjh9u/campanim.html
Activation of cyclic-AMP as a second messenger. (a) The hormone receptor, inactive G protein, and inactive adenylate cyclase enzyme reside in the cell membrane. (b) Formation of the hormone-receptor complex causes the guanosine diphosphate (GDP) on G protein to be replaced with guanosine triphosphate (GTP). (c) The active G protein-GTP complex activates adenylate cyclase, resulting in production of cyclic AMP inside
http://www.owensboro.kctcs.edu/gcaplan/anat2/notes/notes.htm
http://www.owensboro.kctcs.edu/gcaplan/anat2/notes/notes.htm
http://cwx.prenhall.com/bookbind/pubbooks/mcmurrygob/medialib/media_portfolio/20.html
http://www.owensboro.kctcs.edu/gcaplan/anat2/notes/notes.htm
MECANISMOS DE AO HORMONAL
Second Messenger
Cyclic AMP
Epinephrine and norepinephrine, glucagon, luteinizing hormone, follicle stimulating hormone, thyroid-stimulating hormone, calcitonin, parathyroid hormone, antidiuretic hormone,
Calcium and/or
phosphoinositides
Epinephrine and norepinephrine, angiotensin II, antidiuretic hormone, gonadotropin-releasing hormone, thyroid-releasing hormone. Atrial naturetic hormone, nitric oxide
Cyclic GMP