PCP-Disso-v3

Program developed by Anant Ketkar, Vinay Patil and A.R. Paradkar, Dept. of Pharmaceutics, Bharati Vidyapeeth Deemed University, Poona College of Pharmacy, Pune- 38, Maharashtra, India.

% Release (Average with Flux))

Name of the Drug = Batch = Loading Dose in mg = 0 Total no. of Readings, including 'Zero-time' reading = Diffusion Medium = RPM = Volume of Dissolution Medium (ml) = Volume of Sample removed (ml) = Dilution Factor = Slope of Calibration curve = Constant of Calibration curve = R of Calibration curve =
Skin/Membrane used = 0

Date = Done by =

1 29.5900 0.9990 0.1950

Area for diffusion studies (cm2) = 0

RESULTS Sr.No. 1

Time

Avg. %R

SD

Avg. Time Avg. Flux (mcg/cm^2/min) 0.00 0.00

PCP Disso v3

Add values only in SKY BLUE coloured cells.

Extra Tools >>>

It is a must to add the data in the fields marked with ##.

Date Name of the Drug Batch Code Done by (Initials) Unit used for calibration curve Total No. of Readings, including 'Zero-time' reading Dissolution Medium RPM Volume of Dissolution Medium Volume of Sample removed (if Fixed) Dilution Factor (if Fixed) Time in Slope Constant Abs3 0

## ##

## ## ##
29.59 1 Abs4 0

Loading dose in mg ## Dose 1 Dose 2 Dose 3

Sr.No. 1

Time 0

Abs1 0

Abs2 0

Abs5 0

Abs6 0

Extra Tools >>>

Calculator Unit Convertor

Loading dose in mg ## Dose 4 Dose 5 Dose 6

PCP-Disso-v3
Program developed by Anant Ketkar, Vinay Patil and A.R. Paradkar, Dept. of Pharmaceutics, Bharati Vidyapeeth Deemed University, Poona College of Pharmacy, Pune- 38, Maharashtra, India.

% Release (Average) with model fitting

Name of the Drug = Batch = Date = Loading Dose in mg = 0 Total no. of Readings, including 'Zero-time' reading = Done by = Dissolution Medium = RPM = Volume of Dissolution Medium (ml) = Volume of Sample removed (ml) = Dilution Factor = 1 Slope of Calibration curve = 29.5900 Constant of Calibration curve = 0.9990 R of Calibration curve = 0.1950 Model Fitting (Average)R k Zero order #DIV/0! #DIV/0! 0 t-Table at P0.05 (Two Tails), DF=n-2:T-test #VALUE! #VALUE! 1st order #DIV/0! #DIV/0! Best fit model#DIV/0! T-test #VALUE! #VALUE! Matrix #DIV/0! #DIV/0! Parameters for T-test #VALUE! #VALUE! Korsmeyer-Peppas EquationPeppas #DIV/0! #DIV/0! n= #DIV/0! T-test #VALUE! #VALUE! k= #DIV/0! Hix.Crow. #DIV/0! #DIV/0! T-test #VALUE! #VALUE! MODEL FITTING: Residual Sum of Squares RESULTS Zero 1st order Matrix Peppas Hix.Crow. Sr.No. Time Avg. %R SD 0 0 0 0 0 1 -

#DIV/0!

PCP-Disso-v3
Program developed by Anant Ketkar, Vinay Patil and A.R. Paradkar, Dept. of Pharmaceutics, Bharati Vidyapeeth Deemed University, Poona College of Pharmacy, Pune- 38, Maharashtra, India.

% Release (Average) with model fitting, Q(t) and t(x%)

Name of the Drug = Batch = Loading Dose in mg = 0 Total no. of Readings, including 'Zero-time' reading = Dissolution Medium = RPM = Volume of Dissolution Medium (ml) = Volume of Sample removed (ml) = Dilution Factor = Slope of Calibration curve = Constant of Calibration curve = R of Calibration curve = Model Fitting (Average)R k Zero order #DIV/0! #DIV/0! T-test #VALUE! #VALUE! 1st order #DIV/0! #DIV/0! T-test #VALUE! #VALUE! Matrix #DIV/0! #DIV/0! T-test #VALUE! #VALUE! Peppas #DIV/0! #DIV/0! T-test #VALUE! #VALUE! Hix.Crow. #DIV/0! #DIV/0! T-test #VALUE! #VALUE! 0 t-Table at P0.05 (Two Tails), DF=n-2:RESULTS Sr.No. 1 Zero 0 Date = Done by =

1 29.5900 0.9990 0.1950 Best fit modelParameters calculated byQ (t) Time %Released
min

#DIV/0!
0

t (x%)
min

Parameters for Korsmeyer-Peppas Equation#DIV/0! n= #DIV/0! k= 1st order 0 Matrix 0 Peppas Hix.Crow. 0 0 -

MODEL FITTING: Residual Sum of Squares

Time

Avg. %R

SD

PCP-Disso-v3
Program developed by Anant Ketkar, Vinay Patil and A.R. Paradkar, Dept. of Pharmaceutics, Bharati Vidyapeeth Deemed University, Poona College of Pharmacy, Pune- 38, Maharashtra, India.

% Release (Average) with Q(t)

Name of the Drug = Batch = Loading Dose in mg = 0 Total no. of Readings, including 'Zero-time' reading = Dissolution Medium = RPM = Volume of Dissolution Medium (ml) = Volume of Sample removed (ml) = Dilution Factor = Slope of Calibration curve = Constant of Calibration curve = R of Calibration curve = %Released at Time:Time Q (t) min Date = Done by =

1 29.5900 0.9990 0.1950

RESULTS Sr.No. 1

Time

Avg. %R

SD

SE-mean

RSD

PCP-Disso-v3
Program developed by Anant Ketkar, Vinay Patil and A.R. Paradkar, Dept. of Pharmaceutics, Bharati Vidyapeeth Deemed University, Poona College of Pharmacy, Pune- 38, Maharashtra, India.

% Release (Average)
Name of the Drug = Batch = Loading Dose in mg = 0 Total no. of Readings, including 'Zero-time' reading = Dissolution Medium = RPM = Volume of Dissolution Medium (ml) = Volume of Sample removed (ml) = Dilution Factor = Slope of Calibration curve = Constant of Calibration curve = R of Calibration curve = RESULTS Sr.No. 1 Date = Done by =

1 29.5900 0.9990 0.1950

Time

Avg. %R

SD

SE-mean

RSD

PCP-Disso-v3
Program developed by Anant Ketkar, Vinay Patil and A.R. Paradkar, Dept. of Pharmaceutics, Bharati Vidyapeeth Deemed University, Poona College of Pharmacy, Pune- 38, Maharashtra, India.

% Release (Average with %Dissolution Efficiency & Mean Dissolution Time)

Name of the Drug = Batch = Loading Dose in mg = 0 Total no. of Readings, including 'Zero-time' reading = Dissolution Medium = RPM = Volume of Dissolution Medium (ml) = Volume of Sample removed (ml) = Dilution Factor = Slope of Calibration curve = Constant of Calibration curve = R of Calibration curve = RESULTS Sr.No. 1 Date = Done by =

1 29.5900 0.9990 0.1950

Time

Avg. %R

SD

SE-mean Amt. (mg)

% DE 0.00

MDT 0.00

RSD

PCP-Disso-v3
Program developed by Anant Ketkar, Vinay Patil and A.R. Paradkar, Dept. of Pharmaceutics, Bharati Vidyapeeth Deemed University, Poona College of Pharmacy, Pune- 38, Maharashtra, India.

% Release (Average) & model fitting (with constraints) with Q(t) & t(x%)
Name of the Drug = Batch = Loading Dose in mg = 0 Total no. of Readings, including 'Zero-time' reading = Dissolution Medium = RPM = Volume of Dissolution Medium (ml) = Volume of Sample removed (ml) = Dilution Factor = Slope of Calibration curve = Constant of Calibration curve = R of Calibration curve = Model Fitting (Average)R k Zero order #VALUE! #VALUE! T-test #VALUE! #VALUE! 1st order #VALUE! #VALUE! T-test #VALUE! #VALUE! Matrix #VALUE! #VALUE! T-test #VALUE! #VALUE! Peppas #VALUE! #VALUE! T-test #VALUE! #VALUE! Hix.Crow. #VALUE! #VALUE! T-test #VALUE! #VALUE! 0 t-Table at P0.05 (Two Tails), DF=n-2:RESULTS Sr.No. 1 Zero 0 Date = Done by =

1 Constraints for model fitting 29.5900 Lower (%R) = 0 0.9990 Upper (%R) = 0 0.1950 Best fit model#VALUE! Parameters calculated by0 Q (t) t (x%) Time %Released
min
min

Parameters for Korsmeyer-Peppas Equation#VALUE! n= #VALUE! k= 1st order 0 Matrix 0 Peppas Hix.Crow. 0 0 -

MODEL FITTING: Residual Sum of Squares

Time

Avg. %R

SD

PCP-Disso-v3
Program developed by Anant Ketkar, Vinay Patil and A.R. Paradkar, Dept. of Pharmaceutics, Bharati Vidyapeeth Deemed University, Poona College of Pharmacy, Pune- 38, Maharashtra, India.

% Release (Average) & model fitting (with constraints)

Name of the Drug = Batch = Loading Dose in mg = 0 Total no. of Readings, including 'Zero-time' reading = Dissolution Medium = RPM = Volume of Dissolution Medium (ml) = Volume of Sample removed (ml) = Dilution Factor = Slope of Calibration curve = Constant of Calibration curve = R of Calibration curve = Model Fitting (Average)R k Zero order #VALUE! #VALUE! T-test #VALUE! #VALUE! 1st order #VALUE! #VALUE! T-test #VALUE! #VALUE! Matrix #VALUE! #VALUE! T-test #VALUE! #VALUE! Peppas #VALUE! #VALUE! T-test #VALUE! #VALUE! Hix.Crow. #VALUE! #VALUE! T-test #VALUE! #VALUE! 0 t-Table at P0.05 (Two Tails), DF=n-2:RESULTS Sr.No. 1 Zero 0 Date = Done by =

1 29.5900 0.9990 0.1950 Constraints for model fitting Lower (%R) = 0 Upper (%R) = 0

Best fit model-

#VALUE!

Parameters for Korsmeyer-Peppas Equationn= #VALUE! k= #VALUE! 1st order 0 Matrix 0 Peppas Hix.Crow. 0 0 -

MODEL FITTING: Residual Sum of Squares

Time

Avg. %R

SD