"Vezanjem na FcRn receptor monoklonsko protutijelo se reciklira, odnosno odgađa se

razgradnja i produljuje vrijeme poluživota."

https://webcache.googleusercontent.com/search?q=cache:B3m0ws6TXRIJ:https://
repozitorij.pharma.unizg.hr/islandora/object/pharma%253A462/datastream/PDF/
view&cd=16&hl=en&ct=clnk&gl=rs

"Efgartigimod je "prva u klasi" terapija ciljanje FcRn, dizajniran za smanjenje

patogenih IgG antitijela i blokirati IgG recikliranje proces. Uloga FcRn receptora
je spriječiti razgradnju IgG. Stoga, sprečavanjem vezivanja IgG i FcRn, IgG
antitijela koja posreduju autoimune bolesti mogu se brže iscrpiti, čime se smanjuju
simptomi bolesti."
http://hr.hsp-pharma.com/info/67-of-patients-have-significantly-improved-sy-
46349492.html

"FcRn functions as a recycling or transcytosis receptor that is responsible for

maintaining IgG and albumin in the circulation, and bidirectionally transporting
these two ligands across polarized cellular barriers."
https://pubmed.ncbi.nlm.nih.gov/31354709/